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Center for Computational Systems Medicine
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Gene summary

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Gene structure and Gene expression level

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Sex-biased somatic mutation

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DNA methylation with beta values in gene

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Exon skipping events with PSI in TCGA

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RNA A-to-I editing events in TCGA

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Sex-biased TF-Gene network of gene

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Sex-biased RBP-ES network of gene

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Sex-biased CeRNA regulation of gene

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Sex-biased eQTL regulation of gene

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Sex-biased eQTM regulation of gene

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Sex-biased sQTL regulation of gene

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Sex-biased sQTM regulation of gene

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Related disease information of gene

Gene: ENSG00000151882

Summary for CCL28

check button Gene summary

Gene informationEnsembl ID

ENSG00000151882

Gene symbol

CCL28

Gene nameC-C motif chemokine ligand 28
HGNC

17700

Entrez ID

56477

Gene typeprotein_coding
SynonymsCCL28|SCYA28|MEC|CCK1
UniProtAcc

Q9NRJ3


check buttonDrugs associated with this gene(DrugBank).
Gene IDGene SymbolDrug IDDrug NameDrug Type

check buttonCancer therapeutic drugs associated with this gene(NCI).
Gene IDGene NameDrug IDDrug NameDrug TypeCancer

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Structure and expression level for CCL28

check buttonAS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.
UCSC result

check buttonLandscape of gene expressions across multiple cancer types.
gene expression analysis

check buttonDifferentially expressed gene analysis between tumor male and tumor female samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
CCL281.75e+03-1.75e+005.37e-01-3.25e+001.15e-031.26e-02BRCA

check buttonDifferentially expressed gene analysis between tumor male and normal male samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
CCL282.23e+03-1.11e+003.62e-01-3.08e+002.08e-035.35e-03STAD
CCL281.79e+032.36e+003.60e-016.55e+005.78e-113.90e-10KIRP

check buttonDifferentially expressed gene analysis between tumor female and normal female samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
CCL286.84e+021.08e+002.45e-014.43e+009.42e-062.46e-05LUAD
CCL282.48e+03-2.43e+001.80e-01-1.35e+011.54e-411.17e-40BRCA
CCL281.23e+03-2.29e+005.50e-01-4.16e+003.14e-051.76e-04READ

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Sex-biased somatic mutation for CCL28

∗For more information on exon skipping events please check the ExonskipDB database.
Gene IDCancer TypeHugo SymbolMaleFemalepvalorci.upci.lowadjPval

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DNA methylation with beta values for CCL28

check buttonLandscape of DNA methylation across multiple cancer types.
methylation heatmap

check buttonDifferentially expressed CpG sites between male tumor and female tumor patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta

check buttonDifferentially expressed CpG sites between male tumor and male normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
KIRCcg14076417chr5:43412499CGI:chr5:43396795-43397262promoter7.54e-018.74e-01-3.36e+007.76e-041.24e-03-1.20e-01
LUADcg26237003chr5:43413107CGI:chr5:43396795-43397262promoter7.28e-018.54e-01-2.01e+004.43e-024.53e-02-1.27e-01
HNSCcg14076417chr5:43412499CGI:chr5:43396795-43397262promoter5.40e-017.10e-01-3.52e+004.33e-048.92e-04-1.70e-01
HNSCcg26237003chr5:43413107CGI:chr5:43396795-43397262promoter6.87e-018.19e-01-2.79e+005.26e-037.42e-03-1.32e-01
BLCAcg23863670chr5:43411827CGI:chr5:43396795-43397262promoter,gene body7.01e-018.30e-01-2.68e+007.35e-031.11e-02-1.30e-01
KIRPcg26237003chr5:43413107CGI:chr5:43396795-43397262promoter8.95e-017.88e-016.05e+001.49e-095.40e-081.07e-01
CHOLcg03326188chr5:43412363CGI:chr5:43396795-43397262UTR,promoter,exon,gene body4.75e-016.89e-01-2.14e+003.25e-023.87e-02-2.15e-01

check buttonDifferentially expressed CpG sites between female tumor and female normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
BRCAcg26237003chr5:43413107CGI:chr5:43396795-43397262promoter7.18e-018.27e-01-3.55e+003.86e-045.36e-04-1.09e-01
HNSCcg03326188chr5:43412363CGI:chr5:43396795-43397262UTR,promoter,exon,gene body4.59e-013.13e-012.76e+005.78e-031.42e-021.46e-01
COADcg03077492chr5:43412993CGI:chr5:43396795-43397262promoter6.64e-015.06e-012.30e+002.16e-022.75e-021.59e-01
COADcg26237003chr5:43413107CGI:chr5:43396795-43397262promoter5.25e-013.74e-012.33e+001.98e-022.59e-021.50e-01

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Exon skipping events with PSI in TCGA for CCL28

∗Please access ExonSkipDB for exon skipping annotation.
check buttonLandscape of exon skipping events across multiple cancer types.
AS event heatmap

check buttonDifferentially expressed exon skipping events between male tumor and female tumor patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between male tumor and male normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between female tumor and female normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

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RNA A-to-I editing events in TCGA for CCL28

∗Please access CAeditome for RNA editing annotation.
check buttonLandscape of RNA editing events across multiple cancer types.
ED heatmap

check buttonDifferentially expressed RNA editing events between male tumor and female tumor patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre
KIRCCCL28-001chr5_43377370_-1.87e-012.21e-01-2.34e+001.93e-024.45e-02-3.35e-02
KIRCCCL28-001chr5_43377380_-2.88e-012.52e-012.54e+001.12e-024.20e-023.57e-02
KIRCCCL28-001chr5_43377392_-1.94e-012.23e-01-2.30e+002.15e-024.55e-02-2.91e-02
KIRCCCL28-001chr5_43377440_-3.39e-013.14e-012.38e+001.72e-024.41e-022.46e-02
KIRCCCL28-001chr5_43378852_-2.13e-011.90e-012.17e+003.00e-024.67e-022.24e-02
KIRCCCL28-003chr5_43381556_-1.31e-011.73e-01-1.97e+004.84e-024.97e-02-4.21e-02
LUADCCL28-001chr5_43378839_-1.75e-012.28e-01-2.32e+002.01e-023.80e-02-5.31e-02
THCACCL28-001chr5_43378839_-2.03e-011.55e-012.24e+002.50e-024.91e-024.76e-02
THCACCL28-001chr5_43380707_-1.88e-011.42e-012.15e+003.19e-024.91e-024.65e-02
THCACCL28-003chr5_43381559_-1.88e-011.63e-012.80e+005.18e-034.77e-022.52e-02
THCACCL28-003chr5_43381597_-3.21e-012.92e-012.40e+001.64e-024.91e-022.88e-02
THCACCL28-003chr5_43381606_-3.14e-012.82e-012.35e+001.89e-024.91e-023.26e-02
HNSCCCL28-001chr5_43378861_-3.21e-012.42e-012.07e+003.84e-024.59e-027.92e-02
LUSCCCL28-001chr5_43380806_-1.79e-012.46e-01-2.69e+007.11e-034.91e-02-6.72e-02
SKCMCCL28-001chr5_43377335_-1.88e-011.23e-011.97e+004.92e-024.95e-026.52e-02
SKCMCCL28-001chr5_43378849_-4.15e-013.79e-011.98e+004.80e-024.91e-023.67e-02
SKCMCCL28-001chr5_43380584_-1.28e-011.84e-01-2.76e+005.70e-034.90e-02-5.58e-02
SKCMCCL28-003chr5_43381511_-2.21e-012.47e-01-1.99e+004.65e-024.90e-02-2.62e-02
STADCCL28-001chr5_43380621_-1.81e-012.16e-01-2.20e+002.78e-024.96e-02-3.45e-02
LIHCCCL28-001chr5_43377409_-2.28e-011.47e-012.13e+003.29e-024.63e-028.09e-02
LIHCCCL28-003chr5_43381462_-2.52e-013.04e-01-2.42e+001.57e-024.30e-02-5.18e-02
LIHCCCL28-003chr5_43381559_-2.60e-011.91e-012.02e+004.29e-024.82e-026.89e-02
KIRPCCL28-001chr5_43378849_-4.13e-013.33e-013.59e+003.37e-042.82e-027.93e-02
KIRPCCL28-003chr5_43381639_-3.71e-013.36e-012.14e+003.20e-024.72e-023.47e-02
SARCCCL28-001chr5_43377286_-2.06e-012.96e-01-2.25e+002.48e-024.85e-02-9.03e-02
PAADCCL28-001chr5_43377392_-1.52e-012.39e-01-2.79e+005.26e-034.66e-02-8.65e-02
PAADCCL28-001chr5_43377440_-2.92e-013.96e-01-3.76e+001.71e-044.66e-02-1.03e-01
PAADCCL28-003chr5_43381497_-1.31e-011.81e-01-3.13e+001.73e-034.66e-02-5.03e-02
READCCL28-003chr5_43381462_-2.01e-011.58e-012.41e+001.59e-024.85e-024.28e-02
ESCACCL28-001chr5_43377380_-2.52e-013.13e-01-2.12e+003.38e-024.99e-02-6.09e-02
UVMCCL28-001chr5_43377286_-1.73e-012.35e-01-2.24e+002.50e-024.93e-02-6.21e-02

check buttonDifferentially expressed RNA editing events between male tumor and male normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre
KIRCCCL28-003chr5_43381498_-2.13e-011.68e-013.16e+001.57e-035.07e-034.53e-02
KIRCCCL28-003chr5_43381606_-3.33e-012.74e-012.88e+003.94e-039.67e-035.87e-02
THCACCL28-001chr5_43378861_-2.41e-011.69e-012.58e+009.92e-031.89e-027.22e-02
THCACCL28-001chr5_43378878_-2.35e-011.64e-012.88e+004.01e-031.08e-027.12e-02
HNSCCCL28-001chr5_43377286_-2.57e-011.70e-013.11e+001.86e-033.69e-038.75e-02
HNSCCCL28-001chr5_43377288_-2.78e-011.20e-012.84e+004.48e-037.42e-031.58e-01
HNSCCCL28-001chr5_43377383_-2.77e-011.38e-012.19e+002.83e-023.19e-021.39e-01
HNSCCCL28-001chr5_43378852_-2.80e-011.60e-012.87e+004.14e-036.95e-031.20e-01
HNSCCCL28-001chr5_43378861_-3.21e-011.97e-013.19e+001.42e-033.00e-031.24e-01
HNSCCCL28-001chr5_43378874_-2.37e-011.52e-012.72e+006.43e-039.87e-038.55e-02
HNSCCCL28-001chr5_43380635_-2.67e-011.74e-012.62e+008.75e-031.27e-029.30e-02
HNSCCCL28-001chr5_43380716_-2.47e-011.88e-012.67e+007.48e-031.11e-025.87e-02
HNSCCCL28-001chr5_43380806_-1.84e-011.25e-012.16e+003.07e-023.40e-025.89e-02
LUSCCCL28-001chr5_43380598_-1.82e-013.04e-01-2.99e+002.80e-038.80e-03-1.22e-01
LUSCCCL28-003chr5_43381462_-2.13e-012.72e-01-2.55e+001.08e-022.03e-02-5.92e-02
LUSCCCL28-003chr5_43381511_-2.46e-013.87e-01-3.01e+002.61e-038.42e-03-1.40e-01
COADCCL28-001chr5_43378874_-2.38e-011.68e-012.51e+001.20e-021.94e-027.06e-02
COADCCL28-001chr5_43378878_-2.17e-011.43e-013.35e+008.15e-043.78e-037.39e-02
COADCCL28-001chr5_43380715_-2.46e-011.79e-012.05e+004.08e-024.33e-026.69e-02
COADCCL28-001chr5_43380719_-3.36e-012.66e-012.72e+006.43e-031.34e-026.98e-02
COADCCL28-001chr5_43380720_-2.43e-011.82e-012.89e+003.91e-039.61e-036.08e-02
STADCCL28-001chr5_43380583_-2.26e-011.65e-012.05e+004.00e-024.51e-026.13e-02
STADCCL28-001chr5_43380716_-2.96e-012.06e-012.71e+006.64e-031.96e-029.00e-02
KIRPCCL28-001chr5_43377440_-3.11e-014.55e-01-2.65e+008.07e-032.00e-02-1.43e-01
KIRPCCL28-001chr5_43380719_-2.53e-013.62e-01-2.67e+007.61e-031.95e-02-1.08e-01
ESCACCL28-001chr5_43380719_-3.97e-012.81e-012.09e+003.69e-024.19e-021.16e-01

check buttonDifferentially expressed RNA editing events between female tumor and female normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre
BRCACCL28-001chr5_43377286_-2.51e-012.04e-014.98e+006.35e-072.47e-064.78e-02
BRCACCL28-001chr5_43377287_-1.74e-011.24e-013.63e+002.80e-046.31e-044.96e-02
BRCACCL28-001chr5_43377288_-2.04e-011.52e-015.18e+002.21e-079.31e-075.20e-02
BRCACCL28-001chr5_43377308_-1.92e-011.27e-016.61e+003.91e-112.98e-106.49e-02
BRCACCL28-001chr5_43377344_-1.67e-011.26e-013.31e+009.37e-041.84e-034.11e-02
BRCACCL28-001chr5_43377370_-1.92e-011.32e-014.88e+001.06e-063.99e-066.01e-02
BRCACCL28-001chr5_43377380_-2.76e-011.98e-016.93e+004.07e-123.54e-117.83e-02
BRCACCL28-001chr5_43377383_-2.41e-011.47e-018.35e+006.88e-171.15e-159.42e-02
BRCACCL28-001chr5_43377392_-2.34e-011.74e-015.22e+001.82e-077.83e-075.90e-02
BRCACCL28-001chr5_43377409_-1.74e-011.24e-012.39e+001.67e-022.13e-025.02e-02
BRCACCL28-001chr5_43377440_-3.27e-012.67e-014.96e+006.96e-072.69e-065.99e-02
BRCACCL28-001chr5_43377448_-1.66e-011.22e-012.56e+001.05e-021.46e-024.36e-02
BRCACCL28-001chr5_43377473_-2.36e-011.44e-017.99e+001.37e-151.96e-149.19e-02
BRCACCL28-001chr5_43377478_-2.50e-011.82e-015.61e+001.97e-081.00e-076.72e-02
BRCACCL28-001chr5_43377486_-1.81e-011.17e-012.10e+003.59e-023.87e-026.36e-02
BRCACCL28-001chr5_43378086_-1.95e-011.20e-012.35e+001.88e-022.33e-027.56e-02
BRCACCL28-001chr5_43378098_-4.06e-012.35e-017.47e+007.93e-148.89e-131.71e-01
BRCACCL28-001chr5_43378099_-3.20e-011.51e-016.03e+001.59e-099.45e-091.69e-01
BRCACCL28-001chr5_43378151_-2.75e-011.65e-014.16e+003.24e-058.99e-051.10e-01
BRCACCL28-001chr5_43378171_-4.40e-012.70e-017.55e+004.19e-144.91e-131.70e-01
BRCACCL28-001chr5_43378229_-3.08e-012.18e-015.89e+003.85e-092.18e-089.06e-02
BRCACCL28-001chr5_43378239_-2.13e-011.75e-013.19e+001.41e-032.62e-033.77e-02
BRCACCL28-001chr5_43378256_-2.79e-011.97e-016.31e+002.72e-101.83e-098.19e-02
BRCACCL28-001chr5_43378264_-1.94e-011.16e-013.02e+002.55e-034.39e-037.74e-02
BRCACCL28-001chr5_43378345_-3.89e-012.54e-017.96e+001.70e-152.42e-141.36e-01
BRCACCL28-001chr5_43378849_-3.84e-013.32e-013.34e+008.37e-041.67e-035.20e-02
BRCACCL28-001chr5_43378852_-2.34e-011.66e-016.07e+001.29e-097.81e-096.89e-02
BRCACCL28-001chr5_43378861_-2.84e-012.50e-012.04e+004.11e-024.31e-023.40e-02
BRCACCL28-001chr5_43378874_-2.51e-011.92e-015.46e+004.76e-082.26e-075.90e-02
BRCACCL28-001chr5_43378878_-2.36e-011.70e-016.01e+001.80e-091.06e-086.53e-02
BRCACCL28-001chr5_43380583_-1.95e-011.19e-013.33e+008.80e-041.75e-037.58e-02
BRCACCL28-001chr5_43380598_-1.83e-011.31e-014.92e+008.83e-073.36e-065.13e-02
BRCACCL28-001chr5_43380635_-2.48e-011.33e-019.82e+009.30e-233.49e-211.15e-01
BRCACCL28-001chr5_43380715_-2.52e-011.50e-016.65e+002.96e-112.29e-101.02e-01
BRCACCL28-001chr5_43380716_-2.68e-011.47e-011.10e+014.14e-283.58e-261.21e-01
BRCACCL28-001chr5_43380719_-3.67e-012.51e-018.33e+008.20e-171.35e-151.16e-01
BRCACCL28-001chr5_43380720_-2.71e-011.44e-019.38e+006.37e-211.76e-191.28e-01
BRCACCL28-001chr5_43380806_-1.97e-011.36e-014.20e+002.63e-057.46e-056.14e-02
BRCACCL28-003chr5_43381462_-2.27e-011.40e-011.00e+011.47e-236.10e-228.65e-02
BRCACCL28-003chr5_43381497_-1.76e-011.37e-013.98e+006.97e-051.80e-043.86e-02
BRCACCL28-003chr5_43381498_-2.25e-011.43e-017.18e+007.22e-137.03e-128.10e-02
BRCACCL28-003chr5_43381511_-2.67e-011.93e-017.48e+007.44e-148.41e-137.44e-02
BRCACCL28-003chr5_43381559_-2.06e-011.28e-017.74e+009.81e-151.24e-137.82e-02
BRCACCL28-003chr5_43381597_-3.23e-012.24e-018.62e+006.63e-181.25e-169.91e-02
BRCACCL28-003chr5_43381606_-3.21e-012.16e-019.66e+004.51e-221.54e-201.05e-01
KIRCCCL28-003chr5_43381511_-2.77e-011.91e-012.31e+002.07e-023.34e-028.61e-02
THCACCL28-001chr5_43377286_-2.59e-012.09e-013.03e+002.46e-036.49e-034.94e-02
THCACCL28-001chr5_43377409_-1.76e-011.43e-012.07e+003.84e-024.22e-023.32e-02
THCACCL28-001chr5_43377440_-3.09e-012.67e-012.65e+007.97e-031.47e-024.12e-02
THCACCL28-001chr5_43377473_-2.24e-011.91e-012.34e+001.90e-022.61e-023.34e-02
THCACCL28-001chr5_43378268_-2.60e-011.37e-013.37e+007.54e-042.78e-031.23e-01
THCACCL28-001chr5_43378345_-3.88e-013.13e-012.32e+002.03e-022.72e-027.49e-02
THCACCL28-001chr5_43380583_-1.80e-011.27e-012.21e+002.68e-023.32e-025.25e-02
THCACCL28-001chr5_43380715_-2.41e-011.72e-013.18e+001.49e-034.56e-036.83e-02
THCACCL28-001chr5_43380716_-2.46e-011.62e-014.49e+007.03e-068.71e-058.39e-02
THCACCL28-001chr5_43380719_-3.14e-012.41e-013.78e+001.60e-048.79e-047.29e-02
THCACCL28-001chr5_43380720_-2.22e-011.70e-012.98e+002.86e-037.21e-035.17e-02
THCACCL28-001chr5_43380806_-1.91e-011.40e-013.41e+006.54e-042.52e-035.06e-02
THCACCL28-003chr5_43381497_-1.53e-011.19e-012.34e+001.91e-022.62e-023.37e-02
THCACCL28-003chr5_43381498_-2.02e-011.51e-013.38e+007.23e-042.71e-035.11e-02
HNSCCCL28-001chr5_43377440_-3.03e-012.27e-012.08e+003.73e-024.09e-027.54e-02
COADCCL28-001chr5_43377288_-2.21e-011.60e-012.12e+003.43e-024.01e-026.07e-02
COADCCL28-001chr5_43377380_-3.33e-012.14e-012.00e+004.54e-024.70e-021.19e-01
COADCCL28-001chr5_43377392_-2.74e-011.91e-012.36e+001.84e-022.82e-028.35e-02
COADCCL28-001chr5_43377409_-1.93e-011.24e-012.89e+003.81e-031.20e-026.95e-02
COADCCL28-001chr5_43377478_-2.93e-012.02e-012.06e+003.93e-024.26e-029.07e-02
STADCCL28-003chr5_43381559_-2.42e-011.64e-012.09e+003.68e-024.45e-027.80e-02
READCCL28-003chr5_43381597_-3.45e-012.33e-012.31e+002.09e-024.19e-021.12e-01

check buttonProtein coding RNA editing(s).
Editing PositionVariant TypeGene SymbolTranscript IDNTchangeAAchange

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Sex-biased TF-Gene network for CCL28

check buttonTFs related to CCL28.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
TF Gene
Cancer TypeTFTarget GeneMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType
CHOLZNF418CCL283.03e+002.12e-034.35e+009.91e-01Female-biased
CHOLZNF716CCL283.63e+001.34e-024.48e+009.81e-01Female-biased
CHOLZNF879CCL282.80e+004.10e-033.94e+009.82e-01Female-biased
PAADBARX1CCL285.08e+009.88e-014.22e+008.79e-03Male-biased
PAADBPTFCCL284.46e+009.92e-013.23e+001.27e-03Male-biased
PAADCDX2CCL284.77e+009.92e-013.71e+003.25e-03Male-biased
PAADEVX2CCL284.79e+009.92e-013.76e+003.73e-03Male-biased
PAADFEZF1CCL284.13e+009.85e-013.08e+003.16e-03Male-biased
PAADHSFY1CCL285.50e+009.83e-014.76e+001.56e-02Male-biased
PAADHSFY2CCL285.43e+009.89e-014.57e+008.91e-03Male-biased
PAADMSX1CCL285.15e+009.92e-014.18e+005.07e-03Male-biased
PAADMSX2CCL285.10e+009.91e-014.17e+006.27e-03Male-biased
PAADNKX6-1CCL284.49e+009.90e-013.43e+003.17e-03Male-biased
PAADPOU2F2CCL284.92e+009.93e-013.88e+003.49e-03Male-biased
PAADPOU5F1CCL284.92e+009.93e-013.89e+003.78e-03Male-biased
PAADTBX6CCL284.55e+009.84e-013.70e+009.48e-03Male-biased
PAADYY1CCL284.72e+009.87e-013.85e+008.38e-03Male-biased
PAADZFP82CCL284.61e+009.92e-013.50e+002.50e-03Male-biased
PAADZNF33BCCL284.97e+009.95e-013.74e+001.35e-03Male-biased
PAADZNF433CCL285.58e+009.82e-014.84e+001.64e-02Male-biased
PAADZNF442CCL284.36e+009.82e-013.52e+009.72e-03Male-biased
PAADZNF716CCL284.67e+009.92e-013.57e+002.62e-03Male-biased
PAADZNF730CCL284.27e+009.82e-013.40e+008.36e-03Male-biased
PCPGNKX6-1CCL283.20e+006.84e-034.08e+009.81e-01Female-biased
PCPGZFP82CCL283.26e+006.94e-034.14e+009.82e-01Female-biased
PCPGZNF33BCCL283.70e+009.33e-034.52e+009.85e-01Female-biased
SKCMZNF418CCL283.93e+006.82e-035.04e+009.87e-01Female-biased
THYMCDX2CCL284.27e+008.53e-035.00e+009.88e-01Female-biased
THYMEVX2CCL284.29e+009.19e-035.00e+009.87e-01Female-biased
THYMHSFY2CCL284.91e+001.53e-025.50e+009.83e-01Female-biased
THYMMSX1CCL284.76e+009.57e-035.47e+009.89e-01Female-biased
THYMMSX2CCL284.76e+001.20e-025.41e+009.86e-01Female-biased
THYMNKX6-1CCL284.31e+006.55e-035.11e+009.90e-01Female-biased
THYMPOU2F2CCL284.39e+009.93e-035.08e+009.87e-01Female-biased
THYMPOU5F1CCL284.47e+001.31e-025.10e+009.84e-01Female-biased
THYMZFP82CCL284.12e+005.73e-034.95e+009.90e-01Female-biased
THYMZNF33BCCL284.25e+003.92e-035.17e+009.93e-01Female-biased
THYMZNF418CCL284.27e+001.38e-035.46e+009.97e-01Female-biased
THYMZNF716CCL283.98e+003.49e-034.93e+009.92e-01Female-biased
THYMZNF879CCL283.91e+003.26e-034.88e+009.92e-01Female-biased

check buttonCCL28 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for CCL28

check buttonRBPs related to ES in CCL28.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
Cancer TypeRBPTarget ESMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType

check buttonCCL28 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

check buttonSex-biased CeRNA regulation of gene.
Gene IDceRNA(lncRNA-miRNA-mRNA)GroupCancer Type

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Sex-biased eQTL regulation of gene

check buttonSex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
eQTLDescription

check buttonMale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type
rs11742761chr5:44301065:A:G-0.1476152610101310.0430786141384477READFemale-baised eQTL
rs17316984chr5:44315272:C:T-0.1476152610101310.0430786141384477READFemale-baised eQTL
rs17234191chr5:44347482:G:A-0.1476152610101310.0430786141384477READFemale-baised eQTL
rs11743802chr5:44351052:T:C-0.1476152610101310.0430786141384477READFemale-baised eQTL
rs10512849chr5:44384121:C:T-0.1476152610101310.0430786141384477READFemale-baised eQTL
rs72750760chr5:52688575:C:T-0.1393736613243630.000135565948509336LIHCFemale-baised eQTL
rs140773865chr5:52643388:A:G-0.1282600642801270.000350980450974262LIHCFemale-baised eQTL
rs2648732chr5:52776330:A:G--0.1241982365464920.000908843547828471LIHCFemale-baised eQTL
rs79743638chr5:52814738:A:G-0.1239670356984530.000950613658643421LIHCFemale-baised eQTL
rs3096173chr5:52780456:A:G--0.1170104816215380.00230130988872328LIHCFemale-baised eQTL
rs76255385chr5:52815327:G:A-0.1170104816215380.00230130988872328LIHCFemale-baised eQTL
rs16880238chr5:52786729:A:C-0.1110851469801480.00456054044481931LIHCFemale-baised eQTL
rs1363958chr5:52775763:T:C--0.1055832370600790.00861970002431557LIHCFemale-baised eQTL
rs2648733chr5:52775826:A:G--0.1055832370600790.00861970002431557LIHCFemale-baised eQTL
rs72752550chr5:52725159:G:A-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752556chr5:52727951:G:A-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752560chr5:52729807:C:T-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752561chr5:52731100:G:A-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752562chr5:52732635:C:T-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs56926375chr5:52733211:G:T-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs55673164chr5:52736089:C:T-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752564chr5:52736654:A:G-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752565chr5:52737196:C:T-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs72752567chr5:52738202:G:T-0.1039536057611810.00863147985167186LIHCFemale-baised eQTL
rs2548504chr5:52775155:A:G--0.1055385975319680.00875565526989584LIHCFemale-baised eQTL
rs2548503chr5:52775205:T:C--0.1055385975319680.00875565526989584LIHCFemale-baised eQTL
rs1363961chr5:52775365:G:A--0.1055385975319680.00875565526989584LIHCFemale-baised eQTL
rs1363960chr5:52775390:G:A--0.1055385975319680.00875565526989584LIHCFemale-baised eQTL
rs1363959chr5:52775537:C:A--0.1055385975319680.00875565526989584LIHCFemale-baised eQTL
rs72752532chr5:52705921:A:G-0.1039551106673180.00875565526989584LIHCFemale-baised eQTL
rs61561406chr5:52711757:A:G-0.1039551106673180.00875565526989584LIHCFemale-baised eQTL
rs58717249chr5:52717716:G:C-0.1039551106673180.00875565526989584LIHCFemale-baised eQTL
rs184643180chr5:52719768:C:T-0.1039551106673180.00875565526989584LIHCFemale-baised eQTL
rs140681849chr5:52721177:C:T-0.1038980253209930.00878594268660163LIHCFemale-baised eQTL
rs111276746chr5:52723169:A:T-0.1038980253209930.00878594268660163LIHCFemale-baised eQTL
rs1833884chr5:52774720:G:A--0.09543341700383350.0199129856560898LIHCFemale-baised eQTL
rs1833883chr5:52774727:T:C--0.09543341700383350.0199129856560898LIHCFemale-baised eQTL
rs2548506chr5:52775081:G:A--0.08759461808100640.0418257908519705LIHCFemale-baised eQTL
rs2548505chr5:52775096:A:G--0.08754571446987450.042217476298172LIHCFemale-baised eQTL
rs840390chr5:34018518:G:A-0.1177046712298260.00276544308273112BLCAFemale-baised eQTL
rs253190chr5:33994759:G:A-0.1183356189192840.005656168078036BLCAFemale-baised eQTL
rs183670chr5:33992156:G:A-0.1206401471941620.00593327465558692BLCAFemale-baised eQTL
rs171681chr5:33992349:T:C-0.1206401471941620.00593327465558692BLCAFemale-baised eQTL
rs253197chr5:34010407:A:G-0.1075016729612810.00855953644767437BLCAFemale-baised eQTL
rs253199chr5:34011568:G:A-0.1075016729612810.00855953644767437BLCAFemale-baised eQTL
rs253201chr5:34013155:G:C-0.1075016729612810.00855953644767437BLCAFemale-baised eQTL
rs34677chr5:33998663:C:A-0.09925627275160020.0232504643042119BLCAFemale-baised eQTL
rs253193chr5:34009916:C:T-0.08691603502623990.0307626768478443BLCAFemale-baised eQTL
rs253194chr5:34009949:A:G-0.08691603502623990.0307626768478443BLCAFemale-baised eQTL
rs253195chr5:34010201:T:C-0.08691603502623990.0307626768478443BLCAFemale-baised eQTL
rs253196chr5:34010211:G:A-0.08691603502623990.0307626768478443BLCAFemale-baised eQTL
rs253198chr5:34010534:T:C-0.08691603502623990.0307626768478443BLCAFemale-baised eQTL
rs190418chr5:34011251:G:T-0.08691603502623990.0307626768478443BLCAFemale-baised eQTL
rs12520359chr5:33930369:T:A-0.08541236646312070.017429530045676LUADFemale-baised eQTL
rs13177154chr5:35667805:C:A-0.03256642935596740.0482064939728021LUADFemale-baised eQTL
rs17393674chr5:37075819:A:T-0.15145332519260.00556820982905452COADFemale-baised eQTL

check buttonFemale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type
rs62360370chr5:37814387:G:A-0.09955845928427030.00860782388078635BLCAMale-baised eQTL
rs150738565chr5:42933305:G:A-0.07777166820814750.0104567568076511BLCAMale-baised eQTL
rs34426657chr5:42935009:C:T-0.07777166820814750.0104567568076511BLCAMale-baised eQTL
rs79956724chr5:42936078:C:A-0.07777166820814750.0104567568076511BLCAMale-baised eQTL
rs62360373chr5:37820639:G:A-0.09331484735382750.0142660823825799BLCAMale-baised eQTL
rs62360371chr5:37816932:C:T-0.09312064350611770.0147075652871509BLCAMale-baised eQTL
rs2603624chr5:42911303:T:G-0.05516907157049920.0159829372171188BLCAMale-baised eQTL
rs16903732chr5:37811999:G:A-0.0914736780068580.0169347092894264BLCAMale-baised eQTL
rs62360369chr5:37812047:G:C-0.0914736780068580.0169347092894264BLCAMale-baised eQTL
rs11747340chr5:37840346:G:A-0.0985221211674020.0194014966323052BLCAMale-baised eQTL
rs62360376chr5:37854586:A:T-0.0985221211674020.0194014966323052BLCAMale-baised eQTL
rs75220215chr5:37860836:G:T-0.09826122971139740.0200792792561004BLCAMale-baised eQTL
rs62360378chr5:37860899:G:C-0.09826122971139740.0200792792561004BLCAMale-baised eQTL
rs2253157chr5:42906470:A:C-0.05484070095702630.0227433150852177BLCAMale-baised eQTL
rs2603622chr5:42912329:A:G-0.05503534028755390.0244276182930175BLCAMale-baised eQTL
rs421514chr5:42872367:T:G-0.05610591423306590.0278973855432502BLCAMale-baised eQTL
rs2548364chr5:42918380:T:C-0.05756219876999910.0279521761112175BLCAMale-baised eQTL
rs378235chr5:42867900:T:A-0.05568857113914310.0302459283943785BLCAMale-baised eQTL
rs388214chr5:42872369:G:A-0.05568857113914310.0302459283943785BLCAMale-baised eQTL
rs315253chr5:42874399:A:G-0.05568857113914310.0302459283943785BLCAMale-baised eQTL
rs309932chr5:42875352:C:T-0.05568857113914310.0302459283943785BLCAMale-baised eQTL
rs114353553chr5:42859705:A:T-0.05571224282012230.0307263442270741BLCAMale-baised eQTL
rs7701142chr5:42860108:T:C-0.05571224282012230.0307263442270741BLCAMale-baised eQTL
rs315261chr5:42887992:A:G-0.1051804829126110.0316378454965365BLCAMale-baised eQTL
rs9885101chr5:42913209:C:A-0.0532097127932040.0317522178393608BLCAMale-baised eQTL
rs78899997chr5:37833581:G:A-0.09328780589573990.0329141733678173BLCAMale-baised eQTL
rs315246chr5:42884125:A:G-0.05548126353723930.0355854002533155BLCAMale-baised eQTL
rs56000387chr5:37831431:T:C-0.09165946815399360.0361708293525875BLCAMale-baised eQTL
rs17386472chr5:37832696:C:T-0.09165946815399360.0361708293525875BLCAMale-baised eQTL
rs13156119chr5:42911361:A:C-0.05206123862680790.0398748284751468BLCAMale-baised eQTL
rs10044301chr5:42908236:C:A-0.05200745953350980.0399233852020329BLCAMale-baised eQTL
rs4513706chr5:42909188:G:C-0.05175191741720760.0415596943593046BLCAMale-baised eQTL
rs12659760chr5:42909923:C:T-0.05175191741720760.0415596943593046BLCAMale-baised eQTL
rs12655096chr5:42907283:T:C-0.05463111819069330.0441609768767915BLCAMale-baised eQTL
rs75236196chr5:40488557:T:C-0.09658128259303010.000220106989565323LUADMale-baised eQTL
rs77091262chr5:40494051:G:A-0.09658128259303010.000220106989565323LUADMale-baised eQTL
rs78870278chr5:40498079:C:T-0.09768436253107360.00022084930768166LUADMale-baised eQTL
rs149137776chr5:40498229:G:A-0.09768436253107360.00022084930768166LUADMale-baised eQTL
rs113700968chr5:40549520:G:A-0.0898173496299850.000609286017005282LUADMale-baised eQTL
rs10512738chr5:40428699:A:G-0.07949249406623480.0196173557826521LUADMale-baised eQTL
rs73750647chr5:38251076:T:C-0.08783579335688880.0382874094602916LUADMale-baised eQTL
rs73750649chr5:38252643:A:C-0.08783579335688880.0382874094602916LUADMale-baised eQTL
rs73750645chr5:38248397:A:T-0.08473414393699880.0470376506509053LUADMale-baised eQTL
rs73750646chr5:38248982:G:C-0.08473414393699880.0470376506509053LUADMale-baised eQTL

check buttonOpposite sex-biased eQTL regulation.
SNP IDSNP InfoPosition to GeneMale EffectMale FDRFemale EffectFemale FDRSex-biased Gene in CancerCancer Type

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Sex-biased eQTM regulation of gene

check buttonSex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).
eQTMDescription
eQTM boxplot analysisGene ID: ENSG00000151882
CpG Site: cg03326188
Position to Gene: gene,exon,promoter,UTR
Male Effect: -0.412868107714997
Female Effect: -
eQTM boxplot analysisGene ID: ENSG00000151882
CpG Site: cg03326188
Position to Gene: gene,exon,promoter,UTR
Male Effect: -0.0834311502207436
Female Effect: -

check buttonMale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type
cg03326188chr5:43412363gene,exon,promoter,UTR-0.4128681077149973.49559115404865e-15-0.54751912373488217.6740145595780485e-19LUAD
cg03326188chr5:43412363gene,exon,promoter,UTR-0.08343115022074365.48309621201451e-05-0.313986753125998163.413249730589733e-07LIHC

check buttonFemale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type

check buttonOpposite sex-biased eQTM regulation.
CpG SiteCpG PostionCpG IslandPosition to GeneMale EffectMale FDRFemale EffectFemale FDRMale CorMale P-valueFemale CorFemale P-valueSex-biased Coding GeneCancer Type

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Sex-biased sQTL regulation of gene

check buttonSex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTLDescription

check buttonMale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonFemale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonOpposite sex-biased sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESMale EffectMale FDRFemale EffectFemale FDRCancer Type

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Sex-biased sQTM regulation of gene

check buttonSex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTMDescription

check buttonMale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonFemale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonOpposite sex-biased sQTM regulation.
EX IDEX InfoSkipped ExonCPG SiteCPG PositionCPG IslandPosition to EX EventsMale EffectMale FDRFemale EffectFemale FDRMale CorrelationMale P-valueFemale CorrelationFemale P-valueORF_annoCancer Type

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Related disease information of CCL28

check buttonDiseases associated with this gene (DisGeNET).
Gene IDGene SymbolDisease IDDisease NameNumber of PMIDSource