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Gene: ENSG00000150756 |
Summary for FAM173B |
Gene summary |
| Gene information | Ensembl ID | ENSG00000150756 | Gene symbol | FAM173B |
| Gene name | ATP synthase c subunit lysine N-methyltransferase | |
| HGNC | 27029 | |
| Entrez ID | 134145 | |
| Gene type | protein_coding | |
| Synonyms | ATPSCKMT|JS-2 | |
| UniProtAcc | Q6P4H8 |
Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for FAM173B |
AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
Landscape of gene expressions across multiple cancer types. |
Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for FAM173B |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for FAM173B |
Landscape of DNA methylation across multiple cancer types. |
Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| SARC | cg17315844 | chr5:10249001 | CGI:chr5:10249648-10250888 | promoter,gene body | 6.26e-01 | 7.26e-01 | -2.18e+00 | 2.94e-02 | 3.66e-02 | -1.00e-01 |
Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg17315844 | chr5:10249001 | CGI:chr5:10249648-10250888 | promoter,gene body | 7.72e-01 | 9.24e-01 | -3.64e+00 | 2.71e-04 | 4.91e-04 | -1.53e-01 |
| LUSC | cg17315844 | chr5:10249001 | CGI:chr5:10249648-10250888 | promoter,gene body | 4.34e-01 | 9.06e-01 | -4.37e+00 | 1.26e-05 | 5.26e-04 | -4.72e-01 |
| COAD | cg17315844 | chr5:10249001 | CGI:chr5:10249648-10250888 | promoter,gene body | 4.27e-01 | 5.88e-01 | -3.36e+00 | 7.74e-04 | 1.83e-03 | -1.61e-01 |
Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg17315844 | chr5:10249001 | CGI:chr5:10249648-10250888 | promoter,gene body | 6.57e-01 | 9.06e-01 | -8.58e+00 | 9.20e-18 | 4.15e-17 | -2.49e-01 |
Top |
Exon skipping events with PSI in TCGA for FAM173B |
| ∗Please access ExonSkipDB for exon skipping annotation. |
Landscape of exon skipping events across multiple cancer types. |
Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| HNSC | exon_skip_441064 | 7.79e-01 | 8.92e-01 | -3.61e+00 | 3.09e-04 | 1.41e-03 | -1.13e-01 |
| BLCA | exon_skip_441064 | 7.03e-01 | 8.93e-01 | -2.70e+00 | 6.87e-03 | 1.71e-02 | -1.90e-01 |
| STAD | exon_skip_441064 | 8.39e-01 | 9.46e-01 | -4.09e+00 | 4.30e-05 | 6.56e-04 | -1.08e-01 |
| ESCA | exon_skip_441064 | 7.87e-01 | 9.61e-01 | -3.53e+00 | 4.16e-04 | 8.10e-03 | -1.74e-01 |
Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for FAM173B |
| ∗Please access CAeditome for RNA editing annotation. |
Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for FAM173B |
TFs related to FAM173B.∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | ZNF235 | FAM173B | 3.33e+00 | 5.62e-03 | 4.73e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF287 | FAM173B | 3.17e+00 | 7.91e-03 | 4.45e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF334 | FAM173B | 3.31e+00 | 9.01e-03 | 4.55e+00 | 9.82e-01 | Female-biased |
| BRCA | ZNF879 | FAM173B | 3.31e+00 | 9.27e-03 | 4.55e+00 | 9.82e-01 | Female-biased |
| CHOL | ELK4 | FAM173B | 4.92e+00 | 9.92e-01 | 3.77e+00 | 5.28e-03 | Male-biased |
| CHOL | NRF1 | FAM173B | 4.57e+00 | 9.84e-01 | 3.63e+00 | 1.14e-02 | Male-biased |
| MESO | ZNF182 | FAM173B | 4.00e+00 | 9.82e-01 | 2.47e+00 | 3.19e-03 | Male-biased |
| MESO | ZNF22 | FAM173B | 3.97e+00 | 9.82e-01 | 2.42e+00 | 2.94e-03 | Male-biased |
| MESO | ZNF235 | FAM173B | 4.20e+00 | 9.86e-01 | 2.65e+00 | 3.06e-03 | Male-biased |
| MESO | ZNF287 | FAM173B | 4.00e+00 | 9.81e-01 | 2.57e+00 | 4.48e-03 | Male-biased |
FAM173B related gene.∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for FAM173B |
RBPs related to ES in FAM173B.∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LUAD | RBM46 | exon_skip_441070 | 8.09e+00 | 4.52e-03 | 8.51e+00 | 9.89e-01 | Female-biased |
| KIRP | RBM46 | exon_skip_441070 | 8.26e+00 | 3.06e-03 | 8.69e+00 | 9.91e-01 | Female-biased |
| PCPG | RBM46 | exon_skip_441070 | 8.59e+00 | 9.88e-01 | 8.23e+00 | 5.94e-03 | Male-biased |
FAM173B related ES.∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7715544 | chr5:6284050:G:A | - | -0.0879369756005665 | 0.0402600024776142 | HNSC | Female-baised eQTL |
| rs6555307 | chr5:4671361:A:T | - | -0.144054484916263 | 0.00222672431449293 | SARC | Female-baised eQTL |
| rs4543236 | chr5:4672454:C:T | - | -0.153284908934153 | 0.00428099215898519 | SARC | Female-baised eQTL |
| rs13163068 | chr5:4671932:C:A | - | -0.145485773009139 | 0.0049830615223634 | SARC | Female-baised eQTL |
| rs6869159 | chr5:4672142:G:A | - | -0.145485773009139 | 0.0049830615223634 | SARC | Female-baised eQTL |
| rs6555308 | chr5:4671485:C:T | - | -0.137851116784109 | 0.00823447334874858 | SARC | Female-baised eQTL |
| rs4552562 | chr5:4671630:C:T | - | -0.137429654387252 | 0.00838245000030761 | SARC | Female-baised eQTL |
| rs7724465 | chr5:4670751:A:G | - | -0.154269239901315 | 0.0124350161640231 | SARC | Female-baised eQTL |
| rs4329003 | chr5:4672502:A:C | - | -0.138830542528105 | 0.0156543703420801 | SARC | Female-baised eQTL |
| rs6555306 | chr5:4671270:T:C | - | -0.13221503300852 | 0.0169042286418782 | SARC | Female-baised eQTL |
| rs7723123 | chr5:4669845:T:C | - | -0.135353807946397 | 0.0302441117148896 | SARC | Female-baised eQTL |
| rs7737642 | chr5:4669872:C:A | - | -0.135353807946397 | 0.0302441117148896 | SARC | Female-baised eQTL |
| rs6865739 | chr5:10106599:G:A | - | -0.168142866886675 | 0.0119284369552278 | KIRP | Female-baised eQTL |
| rs3849673 | chr5:18160364:G:A | - | 0.10210209617165 | 0.00745447602596038 | LGG | Female-baised eQTL |
| rs7729078 | chr5:18160477:A:G | - | 0.0999419591978966 | 0.010364954799525 | LGG | Female-baised eQTL |
| rs3896348 | chr5:18168447:A:G | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs10037793 | chr5:18168836:A:G | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs12515969 | chr5:18168984:A:G | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs62349769 | chr5:18169397:A:G | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs62349770 | chr5:18169680:C:A | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs6880498 | chr5:18169923:T:C | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs6452120 | chr5:18170288:C:T | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs2386690 | chr5:18170898:C:T | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs2892094 | chr5:18170977:C:T | - | 0.103490783279895 | 0.012935632902888 | LGG | Female-baised eQTL |
| rs13178879 | chr5:18164568:T:C | - | 0.0999182001107343 | 0.0147492130985982 | LGG | Female-baised eQTL |
| rs2892161 | chr5:18165602:C:A | - | 0.0999182001107343 | 0.0147492130985982 | LGG | Female-baised eQTL |
| rs6894110 | chr5:18166513:A:G | - | 0.0980881441288122 | 0.0211554310638765 | LGG | Female-baised eQTL |
| rs6452117 | chr5:18163485:C:T | - | 0.100509103218757 | 0.026180792664853 | LGG | Female-baised eQTL |
| rs2386691 | chr5:18171530:A:C | - | 0.0979321471489455 | 0.0275331700615135 | LGG | Female-baised eQTL |
| rs35150229 | chr5:18169354:T:C | - | 0.100153349126862 | 0.0278771193150995 | LGG | Female-baised eQTL |
| rs13188761 | chr5:18166070:T:C | - | 0.100601839304774 | 0.0285060778199159 | LGG | Female-baised eQTL |
| rs6863113 | chr5:18166772:T:C | - | 0.100246861176635 | 0.0301475299120676 | LGG | Female-baised eQTL |
| rs3911212 | chr5:18162341:G:C | - | 0.0896761799846672 | 0.0311227603607237 | LGG | Female-baised eQTL |
| rs169251 | chr5:6461316:C:T | - | 0.0710162599766897 | 0.00127175093194865 | LUAD | Female-baised eQTL |
| rs272473 | chr5:6460921:C:T | - | 0.0716593980387543 | 0.00177300903584186 | LUAD | Female-baised eQTL |
| rs10076316 | chr5:6456877:G:A | - | 0.0652787332593293 | 0.00332228752864816 | LUAD | Female-baised eQTL |
| rs10076321 | chr5:6456880:G:C | - | 0.0652787332593293 | 0.00332228752864816 | LUAD | Female-baised eQTL |
| rs2657020 | chr5:6456802:G:A | - | 0.0639877586383395 | 0.00389330616665015 | LUAD | Female-baised eQTL |
| rs1174918 | chr5:5905997:G:A | - | 0.0541534133882473 | 0.00719042106949667 | LUAD | Female-baised eQTL |
| rs1175369 | chr5:5908557:T:G | - | 0.0541534133882473 | 0.00719042106949667 | LUAD | Female-baised eQTL |
| rs569786 | chr5:18002966:T:C | - | 0.0570808464508708 | 0.00839772528001061 | LUAD | Female-baised eQTL |
| rs6865222 | chr5:18642563:C:G | - | -0.0642332427801216 | 0.0233301320315366 | LUAD | Female-baised eQTL |
| rs6896565 | chr5:5903520:G:C | - | 0.0491319898077135 | 0.0240655454231297 | LUAD | Female-baised eQTL |
| rs11134131 | chr5:5902613:C:T | - | 0.048623357297177 | 0.028516947550835 | LUAD | Female-baised eQTL |
| rs7708248 | chr5:5901965:A:C | - | 0.0484542378636558 | 0.0296914621996756 | LUAD | Female-baised eQTL |
| rs1174931 | chr5:5893142:C:T | - | 0.0484987099603942 | 0.0354710937066859 | LUAD | Female-baised eQTL |
| rs1175370 | chr5:5907948:A:T | - | 0.0463121454473252 | 0.035853121258008 | LUAD | Female-baised eQTL |
| rs4337858 | chr5:18659471:G:C | - | -0.0625077251291412 | 0.0363608114412329 | LUAD | Female-baised eQTL |
| rs4296806 | chr5:18659481:A:G | - | -0.0625077251291412 | 0.0363608114412329 | LUAD | Female-baised eQTL |
| rs4376269 | chr5:18647237:A:G | - | -0.062609916565393 | 0.0367178999741767 | LUAD | Female-baised eQTL |
| rs4264948 | chr5:18647057:C:T | - | -0.0625071866116865 | 0.0370914773843666 | LUAD | Female-baised eQTL |
| rs7445872 | chr5:18653593:A:G | - | -0.0625071866116865 | 0.0370914773843666 | LUAD | Female-baised eQTL |
| rs7446641 | chr5:18653594:T:C | - | -0.0625071866116865 | 0.0370914773843666 | LUAD | Female-baised eQTL |
| rs10472652 | chr5:18660941:T:C | - | -0.0623426349332925 | 0.0373526729624204 | LUAD | Female-baised eQTL |
| rs10472138 | chr5:18660946:A:G | - | -0.0623426349332925 | 0.0373526729624204 | LUAD | Female-baised eQTL |
| rs10472139 | chr5:18660960:C:T | - | -0.0623426349332925 | 0.0373526729624204 | LUAD | Female-baised eQTL |
| rs7718272 | chr5:18646446:A:C | - | -0.0621639501017263 | 0.0396639921358444 | LUAD | Female-baised eQTL |
| rs2256373 | chr5:5895623:C:A | - | 0.0476067349104208 | 0.0397166597437775 | LUAD | Female-baised eQTL |
| rs883465 | chr5:5893862:T:G | - | 0.0476177109188008 | 0.0399132842009851 | LUAD | Female-baised eQTL |
| rs2243577 | chr5:5894157:A:C | - | 0.0476177109188008 | 0.0399132842009851 | LUAD | Female-baised eQTL |
| rs4538611 | chr5:18655861:T:C | - | -0.0618862074312044 | 0.0411478808365268 | LUAD | Female-baised eQTL |
| rs10056718 | chr5:18657456:T:G | - | -0.0618862074312044 | 0.0411478808365268 | LUAD | Female-baised eQTL |
| rs10077422 | chr5:18657610:C:T | - | -0.0618862074312044 | 0.0411478808365268 | LUAD | Female-baised eQTL |
| rs4866114 | chr5:18658462:A:G | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4576150 | chr5:18658953:T:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4621562 | chr5:18659271:T:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4397135 | chr5:18659399:G:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4397136 | chr5:18659714:G:A | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4509026 | chr5:18659851:A:G | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs10940744 | chr5:18659907:A:G | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs9292282 | chr5:18660562:C:T | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs10472140 | chr5:18661186:A:G | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs10472653 | chr5:18661250:A:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4470767 | chr5:18661952:C:T | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs13167044 | chr5:18662174:T:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs13163337 | chr5:18662403:A:G | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs13180575 | chr5:18662480:G:A | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs13167620 | chr5:18662516:T:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4645333 | chr5:18662913:C:A | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4986757 | chr5:18663110:T:A | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4418106 | chr5:18663153:C:T | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4470768 | chr5:18663201:A:G | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4527608 | chr5:18663384:G:T | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs7723606 | chr5:18663469:C:A | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs6450631 | chr5:18663539:C:T | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs6450632 | chr5:18663659:A:C | - | -0.0613727910372902 | 0.0424105471839995 | LUAD | Female-baised eQTL |
| rs4354047 | chr5:18652965:G:A | - | -0.0583294484551538 | 0.0436635718975118 | LUAD | Female-baised eQTL |
| rs4521478 | chr5:18652970:A:G | - | -0.0583294484551538 | 0.0436635718975118 | LUAD | Female-baised eQTL |
| rs4529196 | chr5:18655144:A:C | - | -0.0583294484551538 | 0.0436635718975118 | LUAD | Female-baised eQTL |
| rs4371760 | chr5:18655279:G:A | - | -0.0583294484551538 | 0.0436635718975118 | LUAD | Female-baised eQTL |
| rs4532365 | chr5:18655395:A:T | - | -0.0583294484551538 | 0.0436635718975118 | LUAD | Female-baised eQTL |
| rs257753 | chr5:15823750:A:G | - | -0.0458065835673591 | 0.0454242316607851 | LUAD | Female-baised eQTL |
| rs79780959 | chr5:18988428:T:C | - | 0.0716619124150907 | 0.0468237991005606 | LUAD | Female-baised eQTL |
| rs75056621 | chr5:18989076:G:A | - | 0.0716619124150907 | 0.0468237991005606 | LUAD | Female-baised eQTL |
| rs4421105 | chr5:18992053:T:C | - | 0.0716619124150907 | 0.0468237991005606 | LUAD | Female-baised eQTL |
| rs4317323 | chr5:18655904:G:A | - | -0.0577059154651303 | 0.0486670187823171 | LUAD | Female-baised eQTL |
| rs10056787 | chr5:18657540:T:C | - | -0.0577059154651303 | 0.0486670187823171 | LUAD | Female-baised eQTL |
| rs1496284 | chr5:18658352:C:T | - | -0.0573579839514676 | 0.0495719235724183 | LUAD | Female-baised eQTL |
| rs4866029 | chr5:18660116:C:T | - | -0.0573579839514676 | 0.0495719235724183 | LUAD | Female-baised eQTL |
| rs9292281 | chr5:18660506:T:A | - | -0.0573579839514676 | 0.0495719235724183 | LUAD | Female-baised eQTL |
| rs329887 | chr5:18702527:G:A | - | -0.0566378735988055 | 0.0490805643850674 | COAD | Female-baised eQTL |
Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11133912 | chr5:1821252:T:C | - | -0.0820989116584174 | 0.00336584750039987 | LGG | Male-baised eQTL |
| rs2291944 | chr5:1799207:T:C | - | -0.0816460105933222 | 0.00551007641538707 | LGG | Male-baised eQTL |
| rs7702843 | chr5:1795263:A:G | - | -0.0811630998575985 | 0.00771977632769415 | LGG | Male-baised eQTL |
| rs972891 | chr5:1800698:G:T | - | -0.0796021446490853 | 0.00793276796417599 | LGG | Male-baised eQTL |
| rs2242412 | chr5:1801575:A:C | - | -0.0796021446490853 | 0.00793276796417599 | LGG | Male-baised eQTL |
| rs4147770 | chr5:1803634:T:C | - | -0.0796021446490853 | 0.00793276796417599 | LGG | Male-baised eQTL |
| rs3776146 | chr5:1807798:A:G | - | -0.0796021446490853 | 0.00793276796417599 | LGG | Male-baised eQTL |
| rs3776144 | chr5:1808747:A:G | - | -0.0796021446490853 | 0.00793276796417599 | LGG | Male-baised eQTL |
| rs6555012 | chr5:1812881:T:C | - | -0.0796021446490853 | 0.00793276796417599 | LGG | Male-baised eQTL |
| rs2276986 | chr5:1797621:A:G | - | -0.0803875710607548 | 0.00817788264233253 | LGG | Male-baised eQTL |
| rs2101721 | chr5:1828950:T:C | - | -0.0779198182508078 | 0.00936555335600167 | LGG | Male-baised eQTL |
| rs34233926 | chr5:1826338:G:A | - | -0.0761182531275032 | 0.0155570579434587 | LGG | Male-baised eQTL |
| rs6554691 | chr5:1248758:T:A | - | -0.0737252747534294 | 0.00389830276575005 | KIRC | Male-baised eQTL |
| rs983856 | chr5:9140736:A:G | - | -0.114908666156968 | 0.0231753793181472 | KIRC | Male-baised eQTL |
| rs12513872 | chr5:1248239:G:A | - | -0.0597226586282377 | 0.0411687481055003 | KIRC | Male-baised eQTL |
| rs1366431 | chr5:4959166:G:A | - | 0.0413188210675433 | 0.0477434138678395 | BLCA | Male-baised eQTL |
| rs10447125 | chr5:19206063:C:T | - | 0.0831171248222035 | 0.0257973154079552 | LUAD | Male-baised eQTL |
| rs168817 | chr5:9089925:G:A | - | -0.062087788243001 | 0.00968695215147623 | COAD | Male-baised eQTL |
| rs253635 | chr5:9092530:G:T | - | -0.0603326175828404 | 0.010091122933455 | COAD | Male-baised eQTL |
| rs253645 | chr5:9099944:T:C | - | -0.0603326175828404 | 0.010091122933455 | COAD | Male-baised eQTL |
| rs253647 | chr5:9101164:A:G | - | -0.0603326175828404 | 0.010091122933455 | COAD | Male-baised eQTL |
| rs2456237 | chr5:9105171:T:C | - | -0.0603326175828404 | 0.010091122933455 | COAD | Male-baised eQTL |
| rs253636 | chr5:9093082:A:C | - | -0.0606876306405811 | 0.0111423601722568 | COAD | Male-baised eQTL |
| rs253639 | chr5:9095283:G:A | - | -0.0606876306405811 | 0.0111423601722568 | COAD | Male-baised eQTL |
| rs253646 | chr5:9100345:T:C | - | -0.0604149066377108 | 0.0118147175005683 | COAD | Male-baised eQTL |
| rs253633 | chr5:9091026:C:G | - | -0.0605307488087784 | 0.0123945519460212 | COAD | Male-baised eQTL |
| rs10941364 | chr5:19570822:C:T | - | 0.0555600822466702 | 0.0200773492070795 | COAD | Male-baised eQTL |
| rs2938063 | chr5:3801033:A:G | - | 0.0731222829926747 | 0.0227685176660345 | COAD | Male-baised eQTL |
| rs253652 | chr5:9115155:T:C | - | -0.0540926280983599 | 0.0232091012163599 | COAD | Male-baised eQTL |
| rs253649 | chr5:9116717:C:T | - | -0.0540926280983599 | 0.0232091012163599 | COAD | Male-baised eQTL |
| rs253648 | chr5:9120276:C:T | - | -0.0539881132115647 | 0.0236845122220021 | COAD | Male-baised eQTL |
| rs253653 | chr5:9114159:A:G | - | -0.0529540284105693 | 0.0300578448335633 | COAD | Male-baised eQTL |
| rs1354572 | chr5:9114464:T:C | - | -0.0529540284105693 | 0.0300578448335633 | COAD | Male-baised eQTL |
| rs975096 | chr5:9114465:T:G | - | -0.052636528904179 | 0.0305125751978371 | COAD | Male-baised eQTL |
| rs2657031 | chr5:9111928:T:C | - | -0.0525147386591451 | 0.0359278005446141 | COAD | Male-baised eQTL |
| rs410514 | chr5:16585126:G:C | - | 0.0521167616152579 | 0.0415846388413661 | COAD | Male-baised eQTL |
| rs272196 | chr5:5053225:A:G | - | -0.0515874919094019 | 0.0439784036729855 | COAD | Male-baised eQTL |
| rs6865569 | chr5:8289477:T:C | - | -0.0575538245906449 | 0.0453425541214226 | COAD | Male-baised eQTL |
| rs7707217 | chr5:8290215:A:C | - | -0.0571726663612996 | 0.0472641882230012 | COAD | Male-baised eQTL |
| rs28751904 | chr5:8290712:A:G | - | -0.0571726663612996 | 0.0472641882230012 | COAD | Male-baised eQTL |
| rs9654460 | chr5:8291303:A:G | - | -0.0571726663612996 | 0.0472641882230012 | COAD | Male-baised eQTL |
| rs12522855 | chr5:8291993:C:T | - | -0.0571726663612996 | 0.0472641882230012 | COAD | Male-baised eQTL |
| rs272188 | chr5:5050367:G:A | - | -0.0515067110504202 | 0.0483011658511166 | COAD | Male-baised eQTL |
| rs272191 | chr5:5050763:G:C | - | -0.0513823458590425 | 0.0491086783512372 | COAD | Male-baised eQTL |
| rs272193 | chr5:5051052:C:T | - | -0.0513282466863062 | 0.0497004442396933 | COAD | Male-baised eQTL |
Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2673896 | chr5:10462020:C:T | Distant upstream | -0.0398810111755031 | 0.00160519134738541 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs1092913 | chr5:10467590:G:A | Distant upstream | -0.0392153815666537 | 0.00247405699207312 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2567573 | chr5:10463685:A:G | Distant upstream | -0.0387914958450445 | 0.00272418248699322 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2648812 | chr5:10463830:T:C | Distant upstream | -0.0387914958450445 | 0.00272418248699322 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2673894 | chr5:10463937:C:T | Distant upstream | -0.0387914958450445 | 0.00272418248699322 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2967951 | chr5:10463995:C:T | Distant upstream | -0.0387914958450445 | 0.00272418248699322 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs7706728 | chr5:10465524:C:A | Distant upstream | -0.0387914958450445 | 0.00272418248699322 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2245638 | chr5:10465817:A:G | Distant upstream | -0.0387914958450445 | 0.00272418248699322 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2648811 | chr5:10463831:A:G | Distant upstream | -0.0386231204662323 | 0.00297680711545835 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2648809 | chr5:10466391:A:G | Distant upstream | -0.0386231204662323 | 0.00297680711545835 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2567574 | chr5:10462632:G:A | Distant upstream | -0.0383276167740332 | 0.00363397116774114 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs12520289 | chr5:10467145:C:A | Distant upstream | -0.0381319246836018 | 0.00399447523158801 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2648813 | chr5:10462657:T:G | Distant upstream | -0.0373188103910514 | 0.00487352827053334 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs814597 | chr5:10468817:C:T | Distant upstream | -0.03737374752879 | 0.00494706939808858 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2589664 | chr5:10462364:A:G | Distant upstream | -0.0325442788038668 | 0.0153737287813378 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs40234 | chr5:9977309:C:T | Distant downstream | -0.0256475688367956 | 0.0229822499565977 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs58045379 | chr5:9980243:C:T | Distant downstream | -0.0252228499793984 | 0.0245029225094371 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs38074 | chr5:9980512:C:G | Distant downstream | -0.0252228499793984 | 0.0245029225094371 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs40233 | chr5:9979013:A:G | Distant downstream | -0.024877204542241 | 0.0279970893474477 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs38076 | chr5:9978960:C:T | Distant downstream | -0.0251222845795248 | 0.0285711251099574 | KIRC | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs12518777 | chr5:11059964:G:A | Distant upstream | 0.0227727417506869 | 0.0128722896509885 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2973510 | chr5:11097748:A:C | Distant upstream | 0.0216196734747988 | 0.029795249725883 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs1024498 | chr5:11097998:T:C | Distant upstream | 0.0213965484047077 | 0.0312954277825873 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs2973504 | chr5:11106002:G:A | Distant upstream | 0.0215524134181917 | 0.0333471548608 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs6898629 | chr5:11101767:G:A | Distant upstream | 0.0236899072386195 | 0.0333976176357148 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs1468305 | chr5:11103878:G:T | Distant upstream | 0.0232652502457489 | 0.0370422759190508 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs75975104 | chr5:11109245:G:A | Distant upstream | 0.0228955834610629 | 0.0485453676984553 | LGG | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs10866482 | chr5:10797425:G:A | Distant upstream | -0.0502936764284201 | 0.043314738502271 | THCA | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs12656313 | chr5:10797520:T:C | Distant upstream | -0.0502936764284201 | 0.043314738502271 | THCA | Male-baised sQTL |
| exon_skip_441064 | chr5:10235210:10235261 | In-frame | rs77662267 | chr5:10798485:T:C | Distant upstream | -0.0502936764284201 | 0.043314738502271 | THCA | Male-baised sQTL |
Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| EX ID: exon_skip_441064 | |
| CpG Site: cg24894783 | |
| Position to EX: Distant upstream | |
| Male Effect: 0.228430065161735 | |
| Female Effect: - |
Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| exon_skip_441064 | chr5:10235210:10235261 | cg24894783 | chr5:10576919 | Distant upstream | 0.228430065161735 | 1.56268057408018e-05 | 0.3041126043194579 | 8.393495229688257e-06 | In-frame | LUAD |
Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of FAM173B |
Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |