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Gene: ENSG00000148606 |
Summary for POLR3A |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000148606 | Gene symbol | POLR3A |
| Gene name | RNA polymerase III subunit A | |
| HGNC | 30074 | |
| Entrez ID | 11128 | |
| Gene type | protein_coding | |
| Synonyms | POLR3A|RPC1|RPC155|hRPC155|C160 | |
| UniProtAcc | O14802 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for POLR3A |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for POLR3A |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for POLR3A |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg13431682 | chr10:78028842 | CGI:chr10:78029380-78029683 | promoter,gene body | 3.69e-01 | 5.68e-01 | -2.64e+00 | 8.21e-03 | 2.48e-02 | -1.99e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg13431682 | chr10:78028842 | CGI:chr10:78029380-78029683 | promoter,gene body | 3.80e-01 | 2.55e-01 | 3.71e+00 | 2.06e-04 | 3.85e-04 | 1.26e-01 |
| HNSC | cg08340277 | chr10:78030381 | CGI:chr10:78029380-78029683 | promoter | 4.17e-01 | 5.25e-01 | -3.97e+00 | 7.30e-05 | 1.99e-04 | -1.08e-01 |
| LUSC | cg08340277 | chr10:78030381 | CGI:chr10:78029380-78029683 | promoter | 4.21e-01 | 6.57e-01 | -4.09e+00 | 4.34e-05 | 5.42e-04 | -2.36e-01 |
| COAD | cg08340277 | chr10:78030381 | CGI:chr10:78029380-78029683 | promoter | 3.92e-01 | 5.23e-01 | -3.54e+00 | 4.05e-04 | 1.08e-03 | -1.31e-01 |
| BLCA | cg08289782 | chr10:78030227 | CGI:chr10:78029380-78029683 | promoter | 2.63e-01 | 3.86e-01 | -3.33e+00 | 8.73e-04 | 2.04e-03 | -1.23e-01 |
| KIRP | cg08340277 | chr10:78030381 | CGI:chr10:78029380-78029683 | promoter | 6.15e-01 | 7.25e-01 | -2.61e+00 | 9.05e-03 | 1.18e-02 | -1.10e-01 |
| CHOL | cg08340277 | chr10:78030381 | CGI:chr10:78029380-78029683 | promoter | 4.19e-01 | 5.28e-01 | -2.06e+00 | 3.90e-02 | 4.26e-02 | -1.09e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg08340277 | chr10:78030381 | CGI:chr10:78029380-78029683 | promoter | 4.24e-01 | 6.06e-01 | -1.10e+01 | 2.52e-28 | 3.02e-27 | -1.82e-01 |
Top |
Exon skipping events with PSI in TCGA for POLR3A |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for POLR3A |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for POLR3A |
| TFs related to POLR3A. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| POLR3A related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for POLR3A |
| RBPs related to ES in POLR3A. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | SAMD4A | exon_skip_51414 | 6.60e+00 | 9.83e-01 | 5.52e+00 | 6.91e-05 | Male-biased |
| READ | PCBP1 | exon_skip_51407 | 9.08e+00 | 4.20e-03 | 9.49e+00 | 9.93e-01 | Female-biased |
| THCA | PCBP1 | exon_skip_51407 | 9.49e+00 | 9.87e-01 | 9.21e+00 | 1.06e-02 | Male-biased |
| POLR3A related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10740341 | chr10:70375577:C:G | - | -0.221540203781264 | 0.00252775903155523 | READ | Female-baised eQTL |
| rs17099306 | chr10:82063533:A:C | - | 0.177731656150068 | 0.00632698818988252 | READ | Female-baised eQTL |
| rs76589414 | chr10:80317198:C:T | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs114457204 | chr10:80321631:C:T | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs76820872 | chr10:80325289:T:C | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs116240977 | chr10:80325427:G:A | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs75419717 | chr10:80341567:C:A | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs77958190 | chr10:80347752:T:G | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs114097582 | chr10:80348187:T:A | - | 0.261588602171653 | 0.0476514402535045 | PAAD | Female-baised eQTL |
| rs77129501 | chr10:80314634:T:G | - | 0.2611674337879 | 0.0492718631347129 | PAAD | Female-baised eQTL |
| rs7901055 | chr10:74655271:C:A | - | 0.105968476456269 | 0.0477774315190957 | SARC | Female-baised eQTL |
| rs16933614 | chr10:76523524:C:G | - | 0.16044727076346 | 7.83866879637437e-05 | STAD | Female-baised eQTL |
| rs11815658 | chr10:76449614:A:G | - | 0.147462705372416 | 0.00847595966360869 | STAD | Female-baised eQTL |
| rs73292569 | chr10:76492285:G:C | - | 0.146446954729707 | 0.0094376960694093 | STAD | Female-baised eQTL |
| rs73292572 | chr10:76495130:T:C | - | 0.146446954729707 | 0.0094376960694093 | STAD | Female-baised eQTL |
| rs16933647 | chr10:76544093:A:G | - | 0.184652185737764 | 0.0121537883808001 | STAD | Female-baised eQTL |
| rs1907346 | chr10:76417694:T:A | - | 0.10538950698504 | 0.0131030081844601 | STAD | Female-baised eQTL |
| rs73292541 | chr10:76433210:C:G | - | 0.120556078186312 | 0.0329694167886637 | STAD | Female-baised eQTL |
| rs112452474 | chr10:76437813:A:T | - | 0.120556078186312 | 0.0329694167886637 | STAD | Female-baised eQTL |
| rs73292524 | chr10:76420368:A:G | - | 0.12028180631736 | 0.03418964047127 | STAD | Female-baised eQTL |
| rs57716415 | chr10:70266964:A:G | - | 0.0513954017414143 | 0.0192292229848552 | LUAD | Female-baised eQTL |
| rs57893993 | chr10:70264874:T:C | - | 0.0506688970700497 | 0.0206313857036329 | LUAD | Female-baised eQTL |
| rs59741815 | chr10:70264593:G:A | - | 0.0503152524667941 | 0.0223018681250065 | LUAD | Female-baised eQTL |
| rs55993119 | chr10:70265552:A:G | - | 0.0503152524667941 | 0.0223018681250065 | LUAD | Female-baised eQTL |
| rs74139291 | chr10:70261874:T:G | - | 0.0512195832218195 | 0.0243953948991336 | LUAD | Female-baised eQTL |
| rs58896152 | chr10:70258816:C:T | - | 0.0505414583547113 | 0.0257751148552527 | LUAD | Female-baised eQTL |
| rs11002437 | chr10:78184854:G:A | - | 0.0395647310338791 | 0.0277453260837585 | LUAD | Female-baised eQTL |
| rs58023772 | chr10:70270583:A:C | - | 0.048584454933872 | 0.0296955745291907 | LUAD | Female-baised eQTL |
| rs16935637 | chr10:78176080:G:A | - | 0.0415288888700951 | 0.0323834434239662 | LUAD | Female-baised eQTL |
| rs72806077 | chr10:78178002:C:A | - | 0.0410216707625632 | 0.0399827490817196 | LUAD | Female-baised eQTL |
| rs10509393 | chr10:78167228:G:A | - | 0.0395433598501845 | 0.0493281898495121 | LUAD | Female-baised eQTL |
| rs17546494 | chr10:71309362:G:A | - | 0.0739335913020218 | 0.0367248456903553 | COAD | Female-baised eQTL |
| rs61851310 | chr10:71309380:A:T | - | 0.0739335913020218 | 0.0367248456903553 | COAD | Female-baised eQTL |
| rs7076474 | chr10:77621798:G:A | - | 0.0513639576082275 | 0.0488299531533062 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2355015 | chr10:86616718:G:A | - | 0.144306258255719 | 0.00569502879233491 | SARC | Male-baised eQTL |
| rs2736692 | chr10:86657761:G:A | - | 0.143842729036601 | 0.00573441704500849 | SARC | Male-baised eQTL |
| rs2254548 | chr10:86659533:C:A | - | 0.143842729036601 | 0.00573441704500849 | SARC | Male-baised eQTL |
| rs2803553 | chr10:86665051:G:A | - | 0.133322777458293 | 0.00713030530722962 | SARC | Male-baised eQTL |
| rs2675698 | chr10:86662240:C:T | - | 0.135355349244503 | 0.0135752928273353 | SARC | Male-baised eQTL |
| rs2803550 | chr10:86662550:G:A | - | 0.135355349244503 | 0.0135752928273353 | SARC | Male-baised eQTL |
| rs2675693 | chr10:86667386:C:T | - | 0.114268396391669 | 0.0357953630189874 | SARC | Male-baised eQTL |
| rs2803556 | chr10:86668546:G:A | - | 0.114268396391669 | 0.0357953630189874 | SARC | Male-baised eQTL |
| rs74984130 | chr10:72032563:C:T | - | 0.0891455412303482 | 0.0102031899788189 | KIRC | Male-baised eQTL |
| rs77657537 | chr10:72032643:A:G | - | 0.0891455412303482 | 0.0102031899788189 | KIRC | Male-baised eQTL |
| rs67368539 | chr10:71539275:C:G | - | -0.0849747085875697 | 0.0156346860316036 | KIRC | Male-baised eQTL |
| rs34887603 | chr10:82525302:A:G | - | 0.108705069801521 | 0.0170325000161528 | KIRC | Male-baised eQTL |
| rs140293303 | chr10:82541528:A:G | - | 0.108705069801521 | 0.0170325000161528 | KIRC | Male-baised eQTL |
| rs67277557 | chr10:71537918:A:G | - | -0.0843793783333447 | 0.0171636775104208 | KIRC | Male-baised eQTL |
| rs56986584 | chr10:72021154:C:T | - | 0.0783513974445862 | 0.0242634953205366 | KIRC | Male-baised eQTL |
| rs111534085 | chr10:72022661:C:T | - | 0.0783513974445862 | 0.0242634953205366 | KIRC | Male-baised eQTL |
| rs10999867 | chr10:71532976:C:T | - | -0.0799161699741408 | 0.0271769056674482 | KIRC | Male-baised eQTL |
| rs75519116 | chr10:72016648:C:G | - | 0.0793421462209155 | 0.031262995625418 | KIRC | Male-baised eQTL |
| rs16929561 | chr10:72017117:G:A | - | 0.0793421462209155 | 0.031262995625418 | KIRC | Male-baised eQTL |
| rs11001014 | chr10:74369074:C:T | - | 0.0512394003152089 | 0.00135900261649307 | BLCA | Male-baised eQTL |
| rs11001020 | chr10:74379459:A:G | - | 0.0445559249457261 | 0.00548982136605991 | BLCA | Male-baised eQTL |
| rs10824118 | chr10:74223915:C:G | - | 0.0470136714067145 | 0.00865667243249674 | BLCA | Male-baised eQTL |
| rs11000912 | chr10:74188719:A:C | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824102 | chr10:74189157:C:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824103 | chr10:74189657:A:T | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824104 | chr10:74192308:A:G | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs12220238 | chr10:74192912:G:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824105 | chr10:74193123:C:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs7073227 | chr10:74193289:G:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs7073432 | chr10:74193592:C:T | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs11000917 | chr10:74196424:C:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824106 | chr10:74198650:A:G | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824111 | chr10:74208798:G:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs11000922 | chr10:74209547:T:G | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs11000923 | chr10:74210244:G:A | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs11000926 | chr10:74215769:C:T | - | 0.047262230627143 | 0.00874203015140717 | BLCA | Male-baised eQTL |
| rs10824115 | chr10:74217639:C:A | - | 0.0470713521098397 | 0.00900239775554887 | BLCA | Male-baised eQTL |
| rs139403509 | chr10:74220344:C:A | - | 0.0470713521098397 | 0.00900239775554887 | BLCA | Male-baised eQTL |
| rs145023314 | chr10:74220373:A:C | - | 0.0470713521098397 | 0.00900239775554887 | BLCA | Male-baised eQTL |
| rs11000901 | chr10:74160213:A:G | - | 0.045575492692494 | 0.0101062967361299 | BLCA | Male-baised eQTL |
| rs12217890 | chr10:74264738:G:A | - | 0.046603690132314 | 0.010179455309571 | BLCA | Male-baised eQTL |
| rs11000945 | chr10:74270981:G:A | - | 0.046603690132314 | 0.010179455309571 | BLCA | Male-baised eQTL |
| rs138188015 | chr10:74133091:A:G | - | 0.0451438978525286 | 0.0106001642830259 | BLCA | Male-baised eQTL |
| rs11000887 | chr10:74137784:C:T | - | 0.0451438978525286 | 0.0106001642830259 | BLCA | Male-baised eQTL |
| rs11000891 | chr10:74144820:G:A | - | 0.0452535821377579 | 0.0106915170448924 | BLCA | Male-baised eQTL |
| rs11000893 | chr10:74146238:T:C | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs12358614 | chr10:74146415:C:T | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs11000894 | chr10:74146840:G:A | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs75467340 | chr10:74147560:C:T | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs11000895 | chr10:74147782:C:T | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs11000897 | chr10:74151518:C:A | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs10824086 | chr10:74152910:T:C | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs11000899 | chr10:74153297:G:A | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs10430521 | chr10:74153832:G:A | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs142855721 | chr10:74159622:T:A | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs10824088 | chr10:74161732:G:C | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs11000905 | chr10:74165774:A:G | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs12357530 | chr10:74168896:C:A | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs2395077 | chr10:74172243:A:G | - | 0.044821645866131 | 0.0122790905251597 | BLCA | Male-baised eQTL |
| rs10740421 | chr10:74181244:T:G | - | 0.0453260647850587 | 0.0124758501077737 | BLCA | Male-baised eQTL |
| rs10430473 | chr10:74155689:C:T | - | 0.0440953409560289 | 0.014865968999845 | BLCA | Male-baised eQTL |
| rs7897778 | chr10:74156347:T:G | - | 0.0440953409560289 | 0.014865968999845 | BLCA | Male-baised eQTL |
| rs11000900 | chr10:74158682:T:A | - | 0.0440953409560289 | 0.014865968999845 | BLCA | Male-baised eQTL |
| rs10824099 | chr10:74183867:T:A | - | 0.0445703309540196 | 0.0150564474108468 | BLCA | Male-baised eQTL |
| rs11000909 | chr10:74185070:A:G | - | 0.0445703309540196 | 0.0150564474108468 | BLCA | Male-baised eQTL |
| rs10824101 | chr10:74187680:T:C | - | 0.0445703309540196 | 0.0150564474108468 | BLCA | Male-baised eQTL |
| rs10824096 | chr10:74177796:G:A | - | 0.0447355588724517 | 0.0154510073783715 | BLCA | Male-baised eQTL |
| rs12359456 | chr10:74178236:C:G | - | 0.0447355588724517 | 0.0154510073783715 | BLCA | Male-baised eQTL |
| rs10824074 | chr10:74116699:T:A | - | 0.0422300169270502 | 0.0168785299327695 | BLCA | Male-baised eQTL |
| rs11000942 | chr10:74265498:G:A | - | 0.0445711598814785 | 0.0169882687120601 | BLCA | Male-baised eQTL |
| rs7083534 | chr10:74195914:C:G | - | 0.0427533706780386 | 0.0209608002454758 | BLCA | Male-baised eQTL |
| rs7894697 | chr10:74217185:C:T | - | 0.0426106457822143 | 0.0213765078376014 | BLCA | Male-baised eQTL |
| rs10824116 | chr10:74217722:A:G | - | 0.0426106457822143 | 0.0213765078376014 | BLCA | Male-baised eQTL |
| rs7898976 | chr10:74218133:C:T | - | 0.0426106457822143 | 0.0213765078376014 | BLCA | Male-baised eQTL |
| rs11000902 | chr10:74160725:G:A | - | 0.0445934867271107 | 0.0225723054572973 | BLCA | Male-baised eQTL |
| rs8255 | chr10:74119992:G:A | - | 0.0412000187837922 | 0.0226805996900082 | BLCA | Male-baised eQTL |
| rs11000890 | chr10:74144315:A:G | - | 0.0411904184810205 | 0.0237823707552819 | BLCA | Male-baised eQTL |
| rs10824082 | chr10:74144322:C:T | - | 0.0411904184810205 | 0.0237823707552819 | BLCA | Male-baised eQTL |
| rs11000936 | chr10:74232625:A:T | - | 0.0422175803162823 | 0.0242590891865732 | BLCA | Male-baised eQTL |
| rs10824122 | chr10:74235238:A:G | - | 0.0422175803162823 | 0.0242590891865732 | BLCA | Male-baised eQTL |
| rs10824077 | chr10:74127280:T:C | - | 0.0394616575443519 | 0.0247577551249305 | BLCA | Male-baised eQTL |
| rs7096553 | chr10:74198077:A:G | - | 0.0420497466001012 | 0.025039111920824 | BLCA | Male-baised eQTL |
| rs10824076 | chr10:74127198:G:A | - | 0.0407525620700352 | 0.0251896514969376 | BLCA | Male-baised eQTL |
| rs11000896 | chr10:74149129:T:C | - | 0.0407586033957203 | 0.0270611850618644 | BLCA | Male-baised eQTL |
| rs12256105 | chr10:74149876:G:A | - | 0.0407586033957203 | 0.0270611850618644 | BLCA | Male-baised eQTL |
| rs10824083 | chr10:74151584:C:G | - | 0.0407586033957203 | 0.0270611850618644 | BLCA | Male-baised eQTL |
| rs10824084 | chr10:74151657:T:C | - | 0.0407586033957203 | 0.0270611850618644 | BLCA | Male-baised eQTL |
| rs10824085 | chr10:74152226:T:C | - | 0.0407586033957203 | 0.0270611850618644 | BLCA | Male-baised eQTL |
| rs7900915 | chr10:78843403:G:A | - | 0.038796415492915 | 0.0272036488047838 | BLCA | Male-baised eQTL |
| rs7905536 | chr10:74237451:G:C | - | 0.0415289614797764 | 0.0287439229258756 | BLCA | Male-baised eQTL |
| rs4746177 | chr10:74153275:G:A | - | 0.0401068690265602 | 0.0318039561755543 | BLCA | Male-baised eQTL |
| rs10824090 | chr10:74163688:C:T | - | 0.0401068690265602 | 0.0318039561755543 | BLCA | Male-baised eQTL |
| rs12252705 | chr10:74225105:A:G | - | 0.0405581151109559 | 0.0345813897559265 | BLCA | Male-baised eQTL |
| rs111704178 | chr10:74197493:G:A | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs6480723 | chr10:74206608:A:G | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs10824112 | chr10:74209245:T:C | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs10824114 | chr10:74210745:T:A | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs10762583 | chr10:74211091:A:G | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs11000924 | chr10:74212553:T:A | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs11000925 | chr10:74212843:G:A | - | 0.0406370404478621 | 0.0358037744346043 | BLCA | Male-baised eQTL |
| rs7922519 | chr10:74216815:G:C | - | 0.0405082272318298 | 0.036389876634812 | BLCA | Male-baised eQTL |
| rs7081350 | chr10:74230570:A:G | - | 0.0405221899019267 | 0.0365088970682946 | BLCA | Male-baised eQTL |
| rs4746187 | chr10:74230840:T:C | - | 0.0405221899019267 | 0.0365088970682946 | BLCA | Male-baised eQTL |
| rs1908334 | chr10:74231963:C:T | - | 0.0405221899019267 | 0.0365088970682946 | BLCA | Male-baised eQTL |
| rs4745740 | chr10:74182711:G:A | - | 0.0397761938310776 | 0.0381670331653274 | BLCA | Male-baised eQTL |
| rs12356618 | chr10:74166434:C:T | - | 0.038780887805717 | 0.0442043773800859 | BLCA | Male-baised eQTL |
| rs145061509 | chr10:74172478:T:C | - | 0.038780887805717 | 0.0442043773800859 | BLCA | Male-baised eQTL |
| rs10824192 | chr10:74491815:G:A | - | 0.0420357778827789 | 0.0451025944783976 | BLCA | Male-baised eQTL |
| rs11000931 | chr10:74225042:C:A | - | 0.0387985398019809 | 0.0464355196045016 | BLCA | Male-baised eQTL |
| rs10824193 | chr10:74502001:G:T | - | 0.0418738347743984 | 0.0471061836915808 | BLCA | Male-baised eQTL |
| rs10824197 | chr10:74523035:T:C | - | 0.0418738347743984 | 0.0471061836915808 | BLCA | Male-baised eQTL |
| rs10824208 | chr10:74597876:A:T | - | 0.0421074756959104 | 0.0472567632934004 | BLCA | Male-baised eQTL |
| rs9665468 | chr10:74179080:C:G | - | 0.0402430923135392 | 0.0481649468624966 | BLCA | Male-baised eQTL |
| rs17655804 | chr10:82062857:A:G | - | 0.144298026585025 | 0.0243206824878072 | LUAD | Male-baised eQTL |
| rs10823496 | chr10:70224806:C:T | - | 0.101027682806743 | 0.0411946071186407 | LUAD | Male-baised eQTL |
| rs1247754 | chr10:77038818:A:G | - | -0.0782538052053701 | 0.000100895653935574 | COAD | Male-baised eQTL |
| rs1247761 | chr10:77063779:T:G | - | -0.073796796831917 | 0.00149599497259632 | COAD | Male-baised eQTL |
| rs12245471 | chr10:76158489:A:T | - | 0.0348671106595044 | 0.00254601613735394 | COAD | Male-baised eQTL |
| rs1720319 | chr10:78287162:C:T | - | 0.0717754531933601 | 0.00637208038127134 | COAD | Male-baised eQTL |
| rs17106475 | chr10:80524550:A:G | - | 0.0614411553251185 | 0.00729633241648645 | COAD | Male-baised eQTL |
| rs72817364 | chr10:80907463:C:T | - | 0.0510408319503642 | 0.00927422695570515 | COAD | Male-baised eQTL |
| rs61851406 | chr10:80908888:A:G | - | 0.0500525473900888 | 0.011105069074168 | COAD | Male-baised eQTL |
| rs57472722 | chr10:80904356:C:T | - | 0.0503312465510146 | 0.0111983709496682 | COAD | Male-baised eQTL |
| rs10887710 | chr10:80270029:T:C | - | 0.0358456300280885 | 0.0286116423110119 | COAD | Male-baised eQTL |
| rs11202403 | chr10:80270068:C:T | - | 0.0358456300280885 | 0.0286116423110119 | COAD | Male-baised eQTL |
| rs149610022 | chr10:80244644:T:C | - | 0.0362572440005228 | 0.0292594144422733 | COAD | Male-baised eQTL |
| rs35213726 | chr10:80252021:G:A | - | 0.0359516543620394 | 0.0317168395920006 | COAD | Male-baised eQTL |
| rs199754007 | chr10:80242887:T:A | - | 0.035813982100408 | 0.0333720210605496 | COAD | Male-baised eQTL |
| rs3851057 | chr10:80260289:G:A | - | 0.0346714668545107 | 0.0396516550146066 | COAD | Male-baised eQTL |
| rs3851058 | chr10:80260477:G:A | - | 0.0346714668545107 | 0.0396516550146066 | COAD | Male-baised eQTL |
| rs11202165 | chr10:80218635:C:T | - | 0.0349747053978127 | 0.0424257182108433 | COAD | Male-baised eQTL |
| rs11202363 | chr10:80259318:A:G | - | 0.0344618549458952 | 0.042648204035573 | COAD | Male-baised eQTL |
| rs200789160 | chr10:80230414:G:A | - | 0.0346702802312497 | 0.0452485591753721 | COAD | Male-baised eQTL |
| rs11202248 | chr10:80231719:G:T | - | 0.0346702802312497 | 0.0452485591753721 | COAD | Male-baised eQTL |
| rs11202256 | chr10:80233733:C:T | - | 0.0346702802312497 | 0.0452485591753721 | COAD | Male-baised eQTL |
| rs150951263 | chr10:80234038:G:C | - | 0.0346702802312497 | 0.0452485591753721 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000148606 |
| CpG Site: cg08340277 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.215350293848227 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg08340277 | chr10:78030381 | promoter | -0.215350293848227 | 5.87122455682483e-12 | -0.4674060303768777 | 3.4392415781318263e-15 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of POLR3A |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000148606 | POLR3A | C2676243 | Leukodystrophy, Hypomyelinating, with Hypodontia and Hypogonadotropic Hypogonadism | 1 | CTD_human |
