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Gene: ENSG00000148426 |
Summary for PROSER2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000148426 | Gene symbol | PROSER2 |
| Gene name | proline and serine rich 2 | |
| HGNC | 23728 | |
| Entrez ID | 254427 | |
| Gene type | protein_coding | |
| Synonyms | PROSER2|MGC35403 | |
| UniProtAcc | Q86WR7 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PROSER2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PROSER2 | 1.37e+03 | -1.04e+00 | 3.64e-01 | -2.86e+00 | 4.29e-03 | 1.20e-02 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PROSER2 | 4.53e+02 | 1.25e+00 | 3.28e-01 | 3.80e+00 | 1.45e-04 | 6.61e-04 | READ |
Top |
Sex-biased somatic mutation for PROSER2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PROSER2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KICH | cg22819767 | chr10:11824911 | CGI:chr10:11823126-11823985 | promoter,gene body | 7.93e-01 | 6.05e-01 | 3.44e+00 | 5.79e-04 | 3.32e-03 | 1.88e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg17989313 | chr10:11824972 | CGI:chr10:11823126-11823985 | promoter,gene body | 7.25e-01 | 8.49e-01 | -2.68e+00 | 7.38e-03 | 1.04e-02 | -1.24e-01 |
| LUSC | cg22819767 | chr10:11824911 | CGI:chr10:11823126-11823985 | promoter,gene body | 7.60e-01 | 8.67e-01 | 2.49e+00 | 1.29e-02 | 1.69e-02 | -1.07e-01 |
| LUSC | cg17989313 | chr10:11824972 | CGI:chr10:11823126-11823985 | promoter,gene body | 6.93e-01 | 8.52e-01 | -2.68e+00 | 7.46e-03 | 1.11e-02 | -1.59e-01 |
| CHOL | cg17989313 | chr10:11824972 | CGI:chr10:11823126-11823985 | promoter,gene body | 7.15e-01 | 5.39e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 1.77e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg17989313 | chr10:11824972 | CGI:chr10:11823126-11823985 | promoter,gene body | 7.50e-01 | 8.60e-01 | -5.78e+00 | 7.44e-09 | 1.68e-08 | -1.10e-01 |
| COAD | cg03411288 | chr10:11823806 | CGI:chr10:11823126-11823985 | promoter,gene body | 2.24e-01 | 1.11e-01 | 2.65e+00 | 7.98e-03 | 1.34e-02 | 1.13e-01 |
| LIHC | cg22819767 | chr10:11824911 | CGI:chr10:11823126-11823985 | promoter,gene body | 6.21e-01 | 3.06e-01 | 2.14e+00 | 3.24e-02 | 3.54e-02 | 3.15e-01 |
Top |
Exon skipping events with PSI in TCGA for PROSER2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PROSER2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PROSER2 |
| TFs related to PROSER2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PROSER2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PROSER2 |
| RBPs related to ES in PROSER2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | SRSF7 | exon_skip_39604 | 8.65e+00 | 1.40e-02 | 9.01e+00 | 9.81e-01 | Female-biased |
| KIRP | SRSF7 | exon_skip_39604 | 8.46e+00 | 7.04e-03 | 8.82e+00 | 9.88e-01 | Female-biased |
| PROSER2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1856582 | chr10:20486502:A:C | - | 0.188195467513097 | 0.0303195382870124 | PAAD | Female-baised eQTL |
| rs16920547 | chr10:20487401:A:G | - | 0.188195467513097 | 0.0303195382870124 | PAAD | Female-baised eQTL |
| rs12358819 | chr10:20489014:G:C | - | 0.188195467513097 | 0.0303195382870124 | PAAD | Female-baised eQTL |
| rs12355916 | chr10:20489122:C:T | - | 0.188195467513097 | 0.0303195382870124 | PAAD | Female-baised eQTL |
| rs148281619 | chr10:5003508:A:G | - | 0.0890818092972291 | 0.0307059645388444 | SARC | Female-baised eQTL |
| rs1000135 | chr10:10812856:T:C | - | 0.122048229088956 | 0.000937149818968438 | BLCA | Female-baised eQTL |
| rs9424104 | chr10:10878030:G:A | - | 0.120295195909878 | 0.00192560770400252 | BLCA | Female-baised eQTL |
| rs9423836 | chr10:10878101:G:A | - | 0.120295195909878 | 0.00192560770400252 | BLCA | Female-baised eQTL |
| rs11256888 | chr10:10878203:A:C | - | 0.120295195909878 | 0.00192560770400252 | BLCA | Female-baised eQTL |
| rs9424105 | chr10:10878449:C:T | - | 0.120295195909878 | 0.00192560770400252 | BLCA | Female-baised eQTL |
| rs9424103 | chr10:10877799:G:C | - | 0.120151565423851 | 0.00203318419635881 | BLCA | Female-baised eQTL |
| rs56184180 | chr10:10792056:A:G | - | 0.118020960841313 | 0.00204803041068189 | BLCA | Female-baised eQTL |
| rs55914802 | chr10:10792060:A:G | - | 0.118020960841313 | 0.00204803041068189 | BLCA | Female-baised eQTL |
| rs11256882 | chr10:10869289:C:T | - | 0.116097228428772 | 0.00210401619082991 | BLCA | Female-baised eQTL |
| rs11256884 | chr10:10870968:G:A | - | 0.115966452905353 | 0.00223164032798152 | BLCA | Female-baised eQTL |
| rs12412835 | chr10:2126831:T:C | - | 0.111593552592916 | 0.0029974750286151 | BLCA | Female-baised eQTL |
| rs9424109 | chr10:10891312:G:A | - | 0.108406069850509 | 0.00301312272567175 | BLCA | Female-baised eQTL |
| rs11256889 | chr10:10879488:T:G | - | 0.115343556935792 | 0.00339886515382563 | BLCA | Female-baised eQTL |
| rs11256883 | chr10:10869337:G:A | - | 0.11086197437633 | 0.00412846043077688 | BLCA | Female-baised eQTL |
| rs17817315 | chr10:2141720:C:T | - | 0.107881378011313 | 0.0046820439748574 | BLCA | Female-baised eQTL |
| rs17520345 | chr10:10816740:A:G | - | 0.105685111036113 | 0.00581641719190275 | BLCA | Female-baised eQTL |
| rs11256844 | chr10:10817189:T:G | - | 0.105685111036113 | 0.00581641719190275 | BLCA | Female-baised eQTL |
| rs11256862 | chr10:10846867:A:T | - | 0.10329178622363 | 0.00694768896696207 | BLCA | Female-baised eQTL |
| rs11256881 | chr10:10866813:G:A | - | 0.102500088365394 | 0.00799386916383248 | BLCA | Female-baised eQTL |
| rs35414759 | chr10:10864084:T:C | - | 0.102283273592364 | 0.00840613779709064 | BLCA | Female-baised eQTL |
| rs12355354 | chr10:10864665:C:T | - | 0.102283273592364 | 0.00840613779709064 | BLCA | Female-baised eQTL |
| rs11256880 | chr10:10866738:C:T | - | 0.102283273592364 | 0.00840613779709064 | BLCA | Female-baised eQTL |
| rs10905836 | chr10:10818593:G:A | - | 0.101880091918499 | 0.00879807366019485 | BLCA | Female-baised eQTL |
| rs7903084 | chr10:10819135:A:T | - | 0.101880091918499 | 0.00879807366019485 | BLCA | Female-baised eQTL |
| rs11256847 | chr10:10820216:G:A | - | 0.101880091918499 | 0.00879807366019485 | BLCA | Female-baised eQTL |
| rs11256841 | chr10:10810069:A:T | - | 0.101802377157379 | 0.00892465007777497 | BLCA | Female-baised eQTL |
| rs9424098 | chr10:10811360:G:C | - | 0.101802377157379 | 0.00892465007777497 | BLCA | Female-baised eQTL |
| rs12777508 | chr10:18513625:T:A | - | 0.124427268971126 | 0.00952510167851983 | BLCA | Female-baised eQTL |
| rs10905830 | chr10:10805637:G:T | - | 0.100175130869975 | 0.00962028501536586 | BLCA | Female-baised eQTL |
| rs11511683 | chr10:10841730:C:A | - | 0.0995138786498433 | 0.0106399259637301 | BLCA | Female-baised eQTL |
| rs12783460 | chr10:10844549:C:T | - | 0.0995138786498433 | 0.0106399259637301 | BLCA | Female-baised eQTL |
| rs11256861 | chr10:10846561:G:T | - | 0.0995138786498433 | 0.0106399259637301 | BLCA | Female-baised eQTL |
| rs12413439 | chr10:2126206:G:T | - | 0.0983300231622539 | 0.0116800919168527 | BLCA | Female-baised eQTL |
| rs12357348 | chr10:10867634:G:A | - | 0.0989926771726695 | 0.0117238140312179 | BLCA | Female-baised eQTL |
| rs12778667 | chr10:10832066:G:A | - | 0.0967832347964589 | 0.013937100193916 | BLCA | Female-baised eQTL |
| rs12783907 | chr10:10832255:G:A | - | 0.0967832347964589 | 0.013937100193916 | BLCA | Female-baised eQTL |
| rs35017521 | chr10:2134000:G:T | - | 0.0929972257604343 | 0.0141481481478068 | BLCA | Female-baised eQTL |
| rs117723189 | chr10:10833945:A:T | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs35098646 | chr10:10834261:A:G | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs34951594 | chr10:10834389:A:C | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs34831777 | chr10:10835154:T:A | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs35423781 | chr10:10835170:G:T | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs12769642 | chr10:10836104:G:A | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs11256856 | chr10:10839053:G:A | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs35566900 | chr10:10840141:G:A | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs34460043 | chr10:10840426:T:C | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs11256866 | chr10:10850441:C:G | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs11256867 | chr10:10850864:G:C | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs7082830 | chr10:10853390:G:A | - | 0.0962282088254539 | 0.0151116889449629 | BLCA | Female-baised eQTL |
| rs12360379 | chr10:10858252:A:T | - | 0.0960077196904017 | 0.0158484331914064 | BLCA | Female-baised eQTL |
| rs34065807 | chr10:10834204:C:G | - | 0.093669960935877 | 0.0193023836243786 | BLCA | Female-baised eQTL |
| rs12766343 | chr10:18474943:C:T | - | 0.103128474879481 | 0.0211732409415256 | BLCA | Female-baised eQTL |
| rs68090620 | chr10:2115256:C:T | - | 0.106313743256733 | 0.0211840652432197 | BLCA | Female-baised eQTL |
| rs12763782 | chr10:10856074:A:G | - | 0.0922188257640491 | 0.0242504505653592 | BLCA | Female-baised eQTL |
| rs12354869 | chr10:10856817:G:A | - | 0.0922188257640491 | 0.0242504505653592 | BLCA | Female-baised eQTL |
| rs2182345 | chr10:18478632:A:G | - | 0.103373581542312 | 0.0260432948509379 | BLCA | Female-baised eQTL |
| rs1113372 | chr10:18478905:G:T | - | 0.103373581542312 | 0.0260432948509379 | BLCA | Female-baised eQTL |
| rs11592112 | chr10:18481134:C:G | - | 0.102115823012346 | 0.0303569264700796 | BLCA | Female-baised eQTL |
| rs9424107 | chr10:10886120:C:A | - | 0.0841888789479378 | 0.0308776786242365 | BLCA | Female-baised eQTL |
| rs3905378 | chr10:18478972:G:A | - | 0.104781697664531 | 0.0322491948405426 | BLCA | Female-baised eQTL |
| rs7099477 | chr10:10888247:A:G | - | -0.0830021842961281 | 0.036417511255647 | BLCA | Female-baised eQTL |
| rs9424108 | chr10:10886938:G:C | - | 0.083002184296128 | 0.036417511255647 | BLCA | Female-baised eQTL |
| rs9424106 | chr10:10883673:C:T | - | 0.0839640138823936 | 0.0401069891880141 | BLCA | Female-baised eQTL |
| rs10905851 | chr10:10866875:A:G | - | 0.0866556182528525 | 0.0421538204676985 | BLCA | Female-baised eQTL |
| rs17148998 | chr10:10867438:G:A | - | 0.0866556182528525 | 0.0421538204676985 | BLCA | Female-baised eQTL |
| rs11599318 | chr10:18477239:A:T | - | 0.100668292713777 | 0.0436150449282981 | BLCA | Female-baised eQTL |
| rs12416359 | chr10:2122265:T:A | - | 0.091502867094444 | 0.0446128650130917 | BLCA | Female-baised eQTL |
| rs7096526 | chr10:18482021:C:T | - | 0.0975798808897665 | 0.0452681611579188 | BLCA | Female-baised eQTL |
| rs10905848 | chr10:10859671:G:C | - | 0.084585588267811 | 0.0495358494501847 | BLCA | Female-baised eQTL |
| rs11009788 | chr10:19406331:G:A | - | -0.0556012823085476 | 0.0298488353673212 | LUAD | Female-baised eQTL |
| rs7908607 | chr10:6899665:C:T | - | 0.0811608583020174 | 0.00481666098446818 | COAD | Female-baised eQTL |
| rs7904733 | chr10:6899127:C:T | - | 0.0808463879596979 | 0.0051217949492512 | COAD | Female-baised eQTL |
| rs7907552 | chr10:6899591:G:T | - | 0.0808463879596979 | 0.0051217949492512 | COAD | Female-baised eQTL |
| rs1243967 | chr10:8130161:G:A | - | -0.0431179653694282 | 0.0256108331843155 | COAD | Female-baised eQTL |
| rs10905528 | chr10:9206783:T:C | - | 0.0427546453497589 | 0.0266766549546055 | COAD | Female-baised eQTL |
| rs7908616 | chr10:6899710:C:T | - | 0.078726762879302 | 0.0296410776647426 | COAD | Female-baised eQTL |
| rs12221287 | chr10:8120803:A:G | - | -0.0414291192355477 | 0.0298365770244257 | COAD | Female-baised eQTL |
| rs1242965 | chr10:9199487:C:T | - | 0.0419212903904524 | 0.0302355267267001 | COAD | Female-baised eQTL |
| rs1242976 | chr10:9196047:G:A | - | 0.0418785003135822 | 0.0306088410662091 | COAD | Female-baised eQTL |
| rs1618145 | chr10:8116711:C:A | - | -0.042942589727023 | 0.031359004703576 | COAD | Female-baised eQTL |
| rs1778072 | chr10:8116806:G:A | - | -0.042942589727023 | 0.031359004703576 | COAD | Female-baised eQTL |
| rs2018086 | chr10:8117577:T:G | - | -0.0419674353052223 | 0.0328307004452067 | COAD | Female-baised eQTL |
| rs1704270 | chr10:8119255:G:T | - | -0.0409317290954876 | 0.0408594562024525 | COAD | Female-baised eQTL |
| rs12774241 | chr10:9222861:T:C | - | 0.0522635652472133 | 0.0418329967966983 | COAD | Female-baised eQTL |
| rs1561361 | chr10:9201852:C:T | - | 0.0399514947024595 | 0.043672097274961 | COAD | Female-baised eQTL |
| rs17148481 | chr10:10609205:C:T | - | 0.0818312267998 | 0.0475007142055218 | COAD | Female-baised eQTL |
| rs72784642 | chr10:8120852:C:T | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs12218090 | chr10:8121159:G:A | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1243985 | chr10:8123821:A:G | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs7907085 | chr10:8123874:T:A | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1243984 | chr10:8124373:C:G | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1704279 | chr10:8126522:T:C | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1704278 | chr10:8126985:A:G | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs7087348 | chr10:8127199:G:T | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs996836 | chr10:8128557:A:T | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs996835 | chr10:8128670:T:G | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1778073 | chr10:8128859:A:G | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1704275 | chr10:8128910:T:C | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs1079484 | chr10:8129345:C:T | - | -0.0399364652936442 | 0.0498624982094401 | COAD | Female-baised eQTL |
| rs7901847 | chr10:8122252:T:C | - | -0.0399290487000088 | 0.0499604268659736 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10764584 | chr10:18546396:T:C | - | -0.0499406577554905 | 0.000294348929366574 | BLCA | Male-baised eQTL |
| rs7077786 | chr10:18603453:C:T | - | -0.0505973544702506 | 0.00173553066591071 | BLCA | Male-baised eQTL |
| rs4747348 | chr10:18506126:G:A | - | -0.0463497516301612 | 0.01267900470461 | BLCA | Male-baised eQTL |
| rs12412932 | chr10:14071283:T:C | - | 0.0619790150892614 | 0.0134008379164278 | BLCA | Male-baised eQTL |
| rs61840399 | chr10:6459762:A:T | - | 0.067117823302133 | 0.021301630500475 | BLCA | Male-baised eQTL |
| rs1917823 | chr10:18528184:G:A | - | -0.0441071785082652 | 0.0257079675040895 | BLCA | Male-baised eQTL |
| rs61840398 | chr10:6459630:G:A | - | 0.063676358614004 | 0.0269816094001236 | BLCA | Male-baised eQTL |
| rs79214873 | chr10:18563610:T:A | - | -0.0387282318357665 | 0.0278272612314623 | BLCA | Male-baised eQTL |
| rs137882235 | chr10:6452234:C:G | - | 0.0648863765711267 | 0.028487930963872 | BLCA | Male-baised eQTL |
| rs187973398 | chr10:6452239:A:G | - | 0.0648863765711267 | 0.028487930963872 | BLCA | Male-baised eQTL |
| rs61840395 | chr10:6454374:C:T | - | 0.0647785142892929 | 0.02902596273606 | BLCA | Male-baised eQTL |
| rs10764587 | chr10:18548901:C:G | - | -0.0384511760524497 | 0.0296786015340082 | BLCA | Male-baised eQTL |
| rs114004025 | chr10:18555116:A:G | - | -0.0384511760524497 | 0.0296786015340082 | BLCA | Male-baised eQTL |
| rs1917209 | chr10:18543631:G:A | - | -0.0382003393232181 | 0.0311287756127857 | BLCA | Male-baised eQTL |
| rs61840396 | chr10:6458087:G:A | - | 0.0643299614426723 | 0.0342492762108856 | BLCA | Male-baised eQTL |
| rs74434289 | chr10:6457968:C:T | - | 0.0640981950992407 | 0.0356904424630236 | BLCA | Male-baised eQTL |
| rs12767068 | chr10:18558322:A:G | - | -0.0377715208679838 | 0.036004920677058 | BLCA | Male-baised eQTL |
| rs11595746 | chr10:6453854:A:G | - | 0.0627997942849429 | 0.0368661336234516 | BLCA | Male-baised eQTL |
| rs199684931 | chr10:6450001:A:C | - | 0.0627187392181916 | 0.0374465315239866 | BLCA | Male-baised eQTL |
| rs150331123 | chr10:6452155:A:G | - | 0.0627187392181916 | 0.0374465315239866 | BLCA | Male-baised eQTL |
| rs142396085 | chr10:6452315:A:G | - | 0.0627187392181916 | 0.0374465315239866 | BLCA | Male-baised eQTL |
| rs10828906 | chr10:18552866:C:T | - | -0.036989572033702 | 0.0407730497493854 | BLCA | Male-baised eQTL |
| rs151317298 | chr10:18566287:C:T | - | -0.0366078588515615 | 0.0442164966061508 | BLCA | Male-baised eQTL |
| rs4747353 | chr10:18548028:C:T | - | -0.0363556019691295 | 0.0467410896124009 | BLCA | Male-baised eQTL |
| rs116555594 | chr10:18557947:G:T | - | -0.0363556019691295 | 0.0467410896124009 | BLCA | Male-baised eQTL |
| rs74135368 | chr10:10625260:A:G | - | 0.0785350105902851 | 0.00496540926908501 | LUAD | Male-baised eQTL |
| rs74135321 | chr10:10618099:T:A | - | 0.0785145023617842 | 0.00496955463903994 | LUAD | Male-baised eQTL |
| rs11250964 | chr10:1963359:A:G | - | 0.0938448001299459 | 0.00904258332052268 | LUAD | Male-baised eQTL |
| rs11813043 | chr10:10624855:A:G | - | 0.0710316832274503 | 0.0129839235990253 | LUAD | Male-baised eQTL |
| rs10508409 | chr10:10628210:C:T | - | 0.0628374583854017 | 0.0302392916177821 | LUAD | Male-baised eQTL |
| rs10218944 | chr10:9945167:G:A | - | 0.057040399139328 | 0.0345597876325715 | LUAD | Male-baised eQTL |
| rs7910874 | chr10:12540690:G:T | - | 0.046894636753105 | 0.0405901513077719 | LUAD | Male-baised eQTL |
| rs11258651 | chr10:13825888:T:C | - | 0.057795344971325 | 0.0284426572263196 | COAD | Male-baised eQTL |
| rs12772400 | chr10:13829153:T:C | - | 0.0567398403748373 | 0.0333264733346244 | COAD | Male-baised eQTL |
| rs11258653 | chr10:13827156:G:A | - | 0.0567867964403019 | 0.0388090164294785 | COAD | Male-baised eQTL |
| rs10508467 | chr10:13827090:T:C | - | 0.0571613161800335 | 0.039089125894319 | COAD | Male-baised eQTL |
| rs10752011 | chr10:5351973:C:T | - | 0.0588431940728109 | 0.0392863161618508 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000148426 |
| CpG Site: cg17989313 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.444540923208939 | |
| Female Effect: - | |
 | Gene ID: ENSG00000148426 |
| CpG Site: cg12377641 | |
| Position to Gene: gene,enhancer | |
| Male Effect: -0.457702685699714 | |
| Female Effect: - | |
 | Gene ID: ENSG00000148426 |
| CpG Site: cg01472043 | |
| Position to Gene: gene,enhancer | |
| Male Effect: -0.457702685699714 | |
| Female Effect: - | |
 | Gene ID: ENSG00000148426 |
| CpG Site: cg01346596 | |
| Position to Gene: gene,enhancer | |
| Male Effect: -0.0757379380211624 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg17989313 | chr10:11824972 | gene,promoter | -0.444540923208939 | 1.41396774705423e-27 | -0.6774376079361945 | 2.6385070737260075e-31 | LUAD |
| cg12377641 | chr10:11826180 | gene,enhancer | -0.457702685699714 | 3.08198733472786e-20 | -0.6070753667214317 | 1.5251451758534982e-23 | STAD |
| cg01472043 | chr10:11826184 | gene,enhancer | -0.457702685699714 | 3.08198733472786e-20 | -0.6070753667214317 | 1.5251451758534982e-23 | STAD |
| cg01346596 | chr10:11826147 | gene,enhancer | -0.0757379380211624 | 9.8261413447333e-07 | -0.3051904016066691 | 2.377230153611345e-09 | HNSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of PROSER2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
