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Gene: ENSG00000146648 |
Summary for EGFR |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000146648 | Gene symbol | EGFR |
| Gene name | epidermal growth factor receptor | |
| HGNC | 3236 | |
| Entrez ID | 1956 | |
| Gene type | protein_coding | |
| Synonyms | EGFR|ERBB1|ERRP | |
| UniProtAcc | P00533 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000146648 | EGFR | DB00002 | Cetuximab | BiotechDrug |
| ENSG00000146648 | EGFR | DB00281 | Lidocaine | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB00317 | Gefitinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB00530 | Erlotinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB01259 | Lapatinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB01269 | Panitumumab | BiotechDrug |
| ENSG00000146648 | EGFR | DB03496 | Alvocidib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB04988 | IGN311 | BiotechDrug |
| ENSG00000146648 | EGFR | DB05101 | Matuzumab | BiotechDrug |
| ENSG00000146648 | EGFR | DB05294 | Vandetanib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB05374 | Rindopepimut | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB05424 | Canertinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB05524 | Pelitinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB05944 | Varlitinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB06021 | AV-412 | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB07602 | S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB07662 | PD-168393 | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB08916 | Afatinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB09330 | Osimertinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB09559 | Necitumumab | BiotechDrug |
| ENSG00000146648 | EGFR | DB10772 | Foreskin keratinocyte (neonatal) | BiotechDrug |
| ENSG00000146648 | EGFR | DB11731 | Depatuxizumab mafodotin | BiotechDrug |
| ENSG00000146648 | EGFR | DB11737 | Icotinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB11828 | Neratinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB11963 | Dacomitinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB12010 | Fostamatinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB12202 | Zalutumumab | BiotechDrug |
| ENSG00000146648 | EGFR | DB12267 | Brigatinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB13164 | Olmutinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB15035 | Zanubrutinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB15327 | Abivertinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB16390 | Mobocertinib | SmallMoleculeDrug |
| ENSG00000146648 | EGFR | DB16695 | Amivantamab | BiotechDrug |
| ENSG00000146648 | EGFR | DB16640 | Almonertinib | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
| ENSG00000146648 | EGFR | DB00002 | Cetuximab | BiotechDrug | Colon Cancer,Rectal Cancer,Head and Neck Cancer |
| ENSG00000146648 | EGFR | DB00317 | Gefitinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB00530 | Erlotinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer,Pancreatic Cancer |
| ENSG00000146648 | EGFR | DB01259 | Lapatinib | SmallMoleculeDrug | Treat Breast Cancer |
| ENSG00000146648 | EGFR | DB01269 | Panitumumab | BiotechDrug | Colon Cancer,Rectal Cancer |
| ENSG00000146648 | EGFR | DB05294 | Vandetanib | SmallMoleculeDrug | Thyroid Cancer |
| ENSG00000146648 | EGFR | DB08916 | Afatinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB09330 | Osimertinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB09559 | Necitumumab | BiotechDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB11828 | Neratinib | SmallMoleculeDrug | Treat Breast Cancer |
| ENSG00000146648 | EGFR | DB11963 | Dacomitinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB12267 | Brigatinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB15035 | Zanubrutinib | SmallMoleculeDrug | Non-Hodgkin Lymphoma |
| ENSG00000146648 | EGFR | DB16390 | Mobocertinib | SmallMoleculeDrug | Non-Small Cell Lung Cancer |
| ENSG00000146648 | EGFR | DB16695 | Amivantamab | BiotechDrug | Non-Small Cell Lung Cancer |
Top |
Structure and expression level for EGFR |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EGFR | 2.78e+03 | -2.18e+00 | 4.52e-01 | -4.83e+00 | 1.37e-06 | 7.77e-05 | BRCA |
| EGFR | 4.52e+04 | -1.31e+00 | 3.47e-01 | -3.78e+00 | 1.59e-04 | 2.08e-02 | ESCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EGFR | 4.66e+03 | -1.46e+00 | 3.66e-01 | -3.99e+00 | 6.61e-05 | 3.04e-04 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EGFR | 4.38e+03 | -1.85e+00 | 1.68e-01 | -1.11e+01 | 2.10e-28 | 1.01e-27 | BRCA |
Top |
Sex-biased somatic mutation for EGFR |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| TCGA-LUAD |
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| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
| ENSG00000146648 | LUAD | EGFR | 17 | 48 | 1.15e-03 | 3.82e-01 | 7.03e-01 | 1.99e-01 | 4.93e-01 |
Top |
DNA methylation with beta values for EGFR |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg22396409 | chr7:55018453 | CGI:chr7:55018448-55020412 | promoter | 2.12e-01 | 9.81e-02 | 3.41e+00 | 6.49e-04 | 1.96e-03 | 1.14e-01 |
| ESCA | cg22396409 | chr7:55018453 | CGI:chr7:55018448-55020412 | promoter | 2.48e-01 | 1.35e-01 | 2.20e+00 | 2.75e-02 | 4.30e-02 | 1.13e-01 |
| CHOL | cg16751451 | chr7:55018398 | CGI:chr7:55018448-55020412 | promoter | 5.30e-01 | 2.77e-01 | 3.46e+00 | 5.30e-04 | 8.63e-03 | 2.53e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg22396409 | chr7:55018453 | CGI:chr7:55018448-55020412 | promoter | 3.20e-01 | 1.55e-01 | 1.01e+01 | 4.88e-24 | 3.79e-23 | 1.65e-01 |
| BRCA | cg03860890 | chr7:55018595 | CGI:chr7:55018448-55020412 | promoter | 3.21e-01 | 1.27e-01 | 1.19e+01 | 7.00e-33 | 1.49e-31 | 1.93e-01 |
| BRCA | cg25311271 | chr7:55019826 | CGI:chr7:55018448-55020412 | promoter,gene body | 1.91e-01 | 7.29e-02 | 9.60e+00 | 7.95e-22 | 5.03e-21 | 1.18e-01 |
| BRCA | cg11849717 | chr7:55020411 | CGI:chr7:55018448-55020412 | promoter,gene body | 3.32e-01 | 9.39e-02 | 9.10e+00 | 8.99e-20 | 4.77e-19 | 2.38e-01 |
| HNSC | cg22396409 | chr7:55018453 | CGI:chr7:55018448-55020412 | promoter | 2.15e-01 | 1.03e-01 | 2.96e+00 | 3.04e-03 | 1.10e-02 | 1.12e-01 |
| HNSC | cg03860890 | chr7:55018595 | CGI:chr7:55018448-55020412 | promoter | 2.13e-01 | 1.11e-01 | 2.97e+00 | 2.93e-03 | 1.09e-02 | 1.01e-01 |
| LIHC | cg16751451 | chr7:55018398 | CGI:chr7:55018448-55020412 | promoter | 4.83e-01 | 3.06e-01 | 3.88e+00 | 1.06e-04 | 4.02e-04 | 1.77e-01 |
Top |
Exon skipping events with PSI in TCGA for EGFR |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for EGFR |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LUAD | EGFR-008 | chr7_55114300_+ | 3.14e-01 | 2.97e-01 | 2.11e+00 | 3.48e-02 | 4.44e-02 | 1.67e-02 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for EGFR |
| TFs related to EGFR. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | BARX1 | EGFR | 3.24e+00 | 5.18e-03 | 4.34e+00 | 9.87e-01 | Female-biased |
| CHOL | FOXA1 | EGFR | 2.65e+00 | 9.95e-04 | 4.13e+00 | 9.89e-01 | Female-biased |
| CHOL | FOXA3 | EGFR | 2.77e+00 | 1.66e-03 | 4.14e+00 | 9.88e-01 | Female-biased |
| CHOL | FOXB1 | EGFR | 2.74e+00 | 1.20e-03 | 4.18e+00 | 9.90e-01 | Female-biased |
| CHOL | FOXD3 | EGFR | 2.61e+00 | 1.05e-03 | 4.08e+00 | 9.88e-01 | Female-biased |
| CHOL | FOXK2 | EGFR | 2.95e+00 | 5.07e-03 | 4.04e+00 | 9.83e-01 | Female-biased |
| CHOL | FOXR2 | EGFR | 2.38e+00 | 6.16e-04 | 3.95e+00 | 9.86e-01 | Female-biased |
| CHOL | LMX1B | EGFR | 2.82e+00 | 3.85e-03 | 3.98e+00 | 9.83e-01 | Female-biased |
| CHOL | MSX1 | EGFR | 2.99e+00 | 3.12e-03 | 4.21e+00 | 9.88e-01 | Female-biased |
| CHOL | MSX2 | EGFR | 2.97e+00 | 3.59e-03 | 4.15e+00 | 9.87e-01 | Female-biased |
| CHOL | NANOG | EGFR | 2.80e+00 | 4.09e-03 | 3.94e+00 | 9.82e-01 | Female-biased |
| CHOL | NKX6-1 | EGFR | 2.40e+00 | 1.02e-03 | 3.87e+00 | 9.84e-01 | Female-biased |
| CHOL | ONECUT3 | EGFR | 3.39e+00 | 5.10e-03 | 4.50e+00 | 9.89e-01 | Female-biased |
| CHOL | POU6F2 | EGFR | 3.48e+00 | 5.73e-03 | 4.55e+00 | 9.89e-01 | Female-biased |
| CHOL | UNCX | EGFR | 3.36e+00 | 6.54e-03 | 4.40e+00 | 9.87e-01 | Female-biased |
| CHOL | ZFP82 | EGFR | 2.68e+00 | 1.61e-03 | 4.05e+00 | 9.87e-01 | Female-biased |
| CHOL | ZNF33B | EGFR | 3.04e+00 | 5.76e-03 | 4.10e+00 | 9.84e-01 | Female-biased |
| CHOL | ZNF418 | EGFR | 2.16e+00 | 5.87e-05 | 4.21e+00 | 9.91e-01 | Female-biased |
| CHOL | ZNF433 | EGFR | 3.88e+00 | 1.41e-02 | 4.73e+00 | 9.82e-01 | Female-biased |
| CHOL | ZNF620 | EGFR | 2.74e+00 | 3.83e-03 | 3.90e+00 | 9.81e-01 | Female-biased |
| LAML | BARX1 | EGFR | 4.60e+00 | 9.91e-01 | 3.22e+00 | 1.75e-03 | Male-biased |
| LAML | FOXA1 | EGFR | 4.24e+00 | 9.87e-01 | 2.45e+00 | 2.78e-04 | Male-biased |
| LAML | FOXA3 | EGFR | 4.22e+00 | 9.86e-01 | 2.57e+00 | 5.22e-04 | Male-biased |
| LAML | FOXB1 | EGFR | 4.23e+00 | 9.86e-01 | 2.52e+00 | 4.01e-04 | Male-biased |
| LAML | FOXD3 | EGFR | 4.34e+00 | 9.89e-01 | 2.57e+00 | 3.16e-04 | Male-biased |
| LAML | FOXR2 | EGFR | 4.17e+00 | 9.86e-01 | 2.12e+00 | 8.31e-05 | Male-biased |
| LAML | LMX1B | EGFR | 4.34e+00 | 9.88e-01 | 2.70e+00 | 5.63e-04 | Male-biased |
| LAML | MSX1 | EGFR | 4.38e+00 | 9.88e-01 | 2.99e+00 | 1.61e-03 | Male-biased |
| LAML | MSX2 | EGFR | 4.34e+00 | 9.87e-01 | 2.90e+00 | 1.34e-03 | Male-biased |
| LAML | NKX6-1 | EGFR | 4.12e+00 | 9.84e-01 | 2.27e+00 | 2.17e-04 | Male-biased |
| LAML | ONECUT3 | EGFR | 4.61e+00 | 9.90e-01 | 3.30e+00 | 2.22e-03 | Male-biased |
| LAML | POU6F2 | EGFR | 4.60e+00 | 9.90e-01 | 3.26e+00 | 2.05e-03 | Male-biased |
| LAML | UNCX | EGFR | 4.57e+00 | 9.90e-01 | 3.22e+00 | 1.96e-03 | Male-biased |
| LAML | ZBTB33 | EGFR | 5.58e+00 | 9.81e-01 | 4.81e+00 | 1.76e-02 | Male-biased |
| LAML | ZFP82 | EGFR | 4.21e+00 | 9.86e-01 | 2.53e+00 | 4.60e-04 | Male-biased |
| LAML | ZNF33B | EGFR | 4.15e+00 | 9.83e-01 | 2.79e+00 | 1.80e-03 | Male-biased |
| LAML | ZNF418 | EGFR | 4.58e+00 | 9.92e-01 | 1.63e+00 | 1.14e-06 | Male-biased |
| LAML | ZNF433 | EGFR | 4.80e+00 | 9.82e-01 | 3.94e+00 | 1.22e-02 | Male-biased |
| LAML | ZNF620 | EGFR | 4.07e+00 | 9.80e-01 | 2.77e+00 | 2.28e-03 | Male-biased |
| LAML | ZNF879 | EGFR | 3.99e+00 | 9.80e-01 | 1.61e+00 | 1.89e-05 | Male-biased |
| READ | ZNF418 | EGFR | 3.22e+00 | 2.47e-03 | 4.42e+00 | 9.89e-01 | Female-biased |
| THYM | FOXR2 | EGFR | 3.40e+00 | 5.79e-03 | 4.22e+00 | 9.82e-01 | Female-biased |
| THYM | NKX6-1 | EGFR | 3.37e+00 | 6.14e-03 | 4.18e+00 | 9.81e-01 | Female-biased |
| THYM | ZNF418 | EGFR | 3.54e+00 | 1.32e-03 | 4.73e+00 | 9.93e-01 | Female-biased |
| THYM | ZNF879 | EGFR | 3.27e+00 | 3.20e-03 | 4.23e+00 | 9.85e-01 | Female-biased |
| EGFR related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for EGFR |
| RBPs related to ES in EGFR. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LUSC | ZC3H10 | exon_skip_466202 | 9.58e+00 | 9.93e-01 | 9.11e+00 | 4.05e-03 | Male-biased |
| ESCA | ZC3H10 | exon_skip_466202 | 9.08e+00 | 1.62e-02 | 9.47e+00 | 9.81e-01 | Female-biased |
| EGFR related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs4947967 | chr7:55071644:T:C | gene | 0.165280172293225 | 0.0144173022570818 | HNSC | Female-baised eQTL |
| rs666800 | chr7:54600051:C:T | - | 0.269342607143099 | 0.000916162295311259 | GBM | Female-baised eQTL |
| rs6963695 | chr7:49198644:T:C | - | -0.205789188246893 | 0.0330530705303923 | GBM | Female-baised eQTL |
| rs883117 | chr7:55239852:G:A | gene | 0.129033578511672 | 0.0304435076814222 | LUSC | Female-baised eQTL |
| rs9649830 | chr7:53575597:C:A | - | 0.126124805291447 | 0.0435978219746254 | LUSC | Female-baised eQTL |
| rs10264027 | chr7:53544205:T:C | - | -0.105949811225728 | 0.0285819539324212 | STAD | Female-baised eQTL |
| rs10251337 | chr7:52535502:A:G | - | 0.0788309107038694 | 0.0339473369516969 | STAD | Female-baised eQTL |
| rs17705151 | chr7:53715524:C:T | - | 0.105235821757757 | 0.0427934477328133 | STAD | Female-baised eQTL |
| rs77619583 | chr7:45644336:C:A | - | 0.0791356398775238 | 0.00153004562662574 | LUAD | Female-baised eQTL |
| rs75112838 | chr7:45642337:T:C | - | 0.0773574412655963 | 0.00202103700081344 | LUAD | Female-baised eQTL |
| rs4523202 | chr7:52130283:C:T | - | 0.0473127894789035 | 0.00228670461734042 | LUAD | Female-baised eQTL |
| rs4358763 | chr7:52130796:T:A | - | 0.0473127894789035 | 0.00228670461734042 | LUAD | Female-baised eQTL |
| rs12155496 | chr7:52132697:C:T | - | 0.0471331319898364 | 0.00240845211151913 | LUAD | Female-baised eQTL |
| rs2465793 | chr7:52119297:A:T | - | 0.0461340043488164 | 0.00281972067802255 | LUAD | Female-baised eQTL |
| rs4947696 | chr7:52115183:C:T | - | 0.0458726045156261 | 0.00325167496873925 | LUAD | Female-baised eQTL |
| rs2465789 | chr7:52116469:C:A | - | 0.0453066030110925 | 0.00345706057320576 | LUAD | Female-baised eQTL |
| rs2465792 | chr7:52118580:G:A | - | 0.0453368855609612 | 0.0034706748962373 | LUAD | Female-baised eQTL |
| rs2464942 | chr7:52125539:G:A | - | 0.0463995806345237 | 0.00370305251308671 | LUAD | Female-baised eQTL |
| rs2953433 | chr7:52126749:C:T | - | 0.0463174705210906 | 0.00394139729520065 | LUAD | Female-baised eQTL |
| rs2953435 | chr7:52127045:G:C | - | 0.0463174705210906 | 0.00394139729520065 | LUAD | Female-baised eQTL |
| rs2953432 | chr7:52120859:G:A | - | 0.0459772505345042 | 0.00404642730223564 | LUAD | Female-baised eQTL |
| rs2465791 | chr7:52117904:T:C | - | 0.0436833768373965 | 0.00484938124514883 | LUAD | Female-baised eQTL |
| rs12718601 | chr7:52140887:T:C | - | 0.0444804779902453 | 0.0051749722035945 | LUAD | Female-baised eQTL |
| rs12718603 | chr7:52141286:A:G | - | 0.0444804779902453 | 0.0051749722035945 | LUAD | Female-baised eQTL |
| rs4273801 | chr7:52141999:C:T | - | 0.0444804779902453 | 0.0051749722035945 | LUAD | Female-baised eQTL |
| rs13243863 | chr7:52143819:A:G | - | 0.0444804779902453 | 0.0051749722035945 | LUAD | Female-baised eQTL |
| rs7459086 | chr7:52144932:C:T | - | 0.0444804779902453 | 0.0051749722035945 | LUAD | Female-baised eQTL |
| rs2953430 | chr7:52115745:T:C | - | 0.0438695776272019 | 0.00617288987094358 | LUAD | Female-baised eQTL |
| rs2952747 | chr7:52115828:T:C | - | 0.0438695776272019 | 0.00617288987094358 | LUAD | Female-baised eQTL |
| rs2953429 | chr7:52115670:C:T | - | 0.0437713502261836 | 0.00634165993575056 | LUAD | Female-baised eQTL |
| rs2952748 | chr7:52115719:T:C | - | 0.0438785231191378 | 0.00637323062794208 | LUAD | Female-baised eQTL |
| rs1357111 | chr7:45644945:G:A | - | 0.063193735463438 | 0.0128609648852013 | LUAD | Female-baised eQTL |
| rs35541134 | chr7:52264024:C:T | - | 0.0532836800310387 | 0.0135549518728477 | LUAD | Female-baised eQTL |
| rs4613946 | chr7:52148810:T:C | - | 0.0407696029172439 | 0.0203813235701386 | LUAD | Female-baised eQTL |
| rs62463184 | chr7:52257734:C:G | - | 0.0483499611867071 | 0.0311829701218785 | LUAD | Female-baised eQTL |
| rs12669343 | chr7:52239748:T:C | - | 0.0483507744526269 | 0.0374927334245674 | LUAD | Female-baised eQTL |
| rs2464943 | chr7:52123744:T:G | - | 0.0455572292642524 | 0.0417456697530183 | LUAD | Female-baised eQTL |
| rs7349972 | chr7:52246609:G:C | - | 0.0468518216587059 | 0.041754443132346 | LUAD | Female-baised eQTL |
| rs34154333 | chr7:45639422:A:G | - | 0.0492401916376134 | 0.0442730800933008 | LUAD | Female-baised eQTL |
| rs2215542 | chr7:52249090:G:A | - | 0.0465396890554377 | 0.0445067441532689 | LUAD | Female-baised eQTL |
| rs59345161 | chr7:52257155:C:A | - | 0.0461758411540475 | 0.0472013146060598 | LUAD | Female-baised eQTL |
| rs73100342 | chr7:47086037:T:C | - | 0.0597353133555186 | 0.00873432330858705 | COAD | Female-baised eQTL |
| rs10487763 | chr7:47084225:T:G | - | 0.0595516541485277 | 0.00921659346114315 | COAD | Female-baised eQTL |
| rs73100337 | chr7:47084281:A:G | - | 0.0595516541485277 | 0.00921659346114315 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11238144 | chr7:51887096:C:T | - | 0.134092237239 | 0.0225011594630548 | GBM | Male-baised eQTL |
| rs11238145 | chr7:51887128:G:A | - | 0.134092237239 | 0.0225011594630548 | GBM | Male-baised eQTL |
| rs13241879 | chr7:54583079:C:T | - | 0.107042424166766 | 2.63318341153746e-07 | LUSC | Male-baised eQTL |
| rs143821544 | chr7:55964880:C:T | - | 0.0795873113140665 | 0.00297757771399952 | LUSC | Male-baised eQTL |
| rs118175268 | chr7:55970055:G:A | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs34874704 | chr7:55975558:G:A | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs75703490 | chr7:55977029:T:C | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs71543773 | chr7:55979919:G:A | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs13232756 | chr7:55980139:C:T | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs13239795 | chr7:55987634:C:T | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs142097271 | chr7:55990490:C:T | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs35092795 | chr7:55995921:T:C | - | 0.0788411708231647 | 0.00305267197938821 | LUSC | Male-baised eQTL |
| rs3813504 | chr7:55962527:T:C | - | 0.0772182759870583 | 0.00407498196383735 | LUSC | Male-baised eQTL |
| rs13226699 | chr7:56079044:G:A | - | 0.0678644486686596 | 0.00762995910200652 | LUSC | Male-baised eQTL |
| rs35046650 | chr7:56081432:C:T | - | 0.0678644486686596 | 0.00762995910200652 | LUSC | Male-baised eQTL |
| rs13238521 | chr7:56082246:G:A | - | 0.0678644486686596 | 0.00762995910200652 | LUSC | Male-baised eQTL |
| rs13238899 | chr7:56072925:T:G | - | 0.0660451471802649 | 0.0101294088212015 | LUSC | Male-baised eQTL |
| rs28498258 | chr7:55958399:C:T | - | 0.0708867151848507 | 0.0109850127248903 | LUSC | Male-baised eQTL |
| rs13236894 | chr7:56099258:C:T | - | 0.069353886852191 | 0.0227676667612445 | LUSC | Male-baised eQTL |
| rs3735066 | chr7:56078311:G:A | - | 0.0673033343109997 | 0.0284572022627998 | LUSC | Male-baised eQTL |
| rs76519777 | chr7:56072855:T:C | - | 0.0666330047866064 | 0.0295865571501132 | LUSC | Male-baised eQTL |
| rs35307785 | chr7:56082414:G:A | - | 0.0675299249526126 | 0.0301877592087342 | LUSC | Male-baised eQTL |
| rs2242510 | chr7:56084123:C:G | - | 0.0675299249526126 | 0.0301877592087342 | LUSC | Male-baised eQTL |
| rs35829286 | chr7:56120348:A:G | - | 0.0704613251477933 | 0.0309517753516644 | LUSC | Male-baised eQTL |
| rs35630212 | chr7:56126137:C:A | - | 0.0704613251477933 | 0.0309517753516644 | LUSC | Male-baised eQTL |
| rs13233028 | chr7:56128436:C:T | - | 0.0704613251477933 | 0.0309517753516644 | LUSC | Male-baised eQTL |
| rs34337311 | chr7:56129885:A:G | - | 0.0704613251477933 | 0.0309517753516644 | LUSC | Male-baised eQTL |
| rs13241227 | chr7:56054722:A:G | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs13238152 | chr7:56057127:C:T | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs35704704 | chr7:56057366:G:T | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs74786312 | chr7:56064982:G:A | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs139342133 | chr7:56068066:G:A | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs71543784 | chr7:56069955:C:G | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs71543785 | chr7:56070238:A:T | - | 0.0668040731609198 | 0.0317197592357535 | LUSC | Male-baised eQTL |
| rs78864849 | chr7:56040878:A:G | - | 0.0666375246896737 | 0.033020740890863 | LUSC | Male-baised eQTL |
| rs35210477 | chr7:56044524:A:G | - | 0.0666375246896737 | 0.033020740890863 | LUSC | Male-baised eQTL |
| rs75544428 | chr7:56085846:T:C | - | 0.0656743433366659 | 0.040168373463695 | LUSC | Male-baised eQTL |
| rs78640831 | chr7:45214985:C:G | - | 0.0580440891407405 | 0.0406079224044492 | LUSC | Male-baised eQTL |
| rs62459185 | chr7:45213031:G:A | - | 0.05792635030024 | 0.0418893606758308 | LUSC | Male-baised eQTL |
| rs610861 | chr7:54671679:A:T | - | -0.131323218678166 | 0.000117906531045973 | STAD | Male-baised eQTL |
| rs815947 | chr7:55446873:G:A | - | -0.0618906691897398 | 0.00191613253919408 | LGG | Male-baised eQTL |
| rs1534130 | chr7:55242039:A:G | gene | -0.0687423063770281 | 0.0019416733351065 | LGG | Male-baised eQTL |
| rs2017011 | chr7:52754441:T:C | - | 0.0981246488202916 | 0.0143983459177492 | LGG | Male-baised eQTL |
| rs35197677 | chr7:52747681:T:G | - | 0.0939272408353501 | 0.0221374201990103 | LGG | Male-baised eQTL |
| rs80167410 | chr7:52749053:C:A | - | 0.0939272408353501 | 0.0221374201990103 | LGG | Male-baised eQTL |
| rs117645905 | chr7:52756342:C:T | - | 0.0939272408353501 | 0.0221374201990103 | LGG | Male-baised eQTL |
| rs17683100 | chr7:52760645:G:A | - | 0.0939272408353501 | 0.0221374201990103 | LGG | Male-baised eQTL |
| rs9691864 | chr7:54824378:G:A | - | 0.039480670176401 | 0.0223488943545323 | LGG | Male-baised eQTL |
| rs17682796 | chr7:52743232:C:T | - | 0.0919698228427893 | 0.0238582981047456 | LGG | Male-baised eQTL |
| rs17135301 | chr7:52764325:T:G | - | 0.0914394104090643 | 0.0259962258374299 | LGG | Male-baised eQTL |
| rs79358636 | chr7:52765709:G:A | - | 0.0908434135627322 | 0.028396286056844 | LGG | Male-baised eQTL |
| rs78017602 | chr7:52773527:C:T | - | 0.0908434135627322 | 0.028396286056844 | LGG | Male-baised eQTL |
| rs17683499 | chr7:52774498:C:T | - | 0.0908434135627322 | 0.028396286056844 | LGG | Male-baised eQTL |
| rs77406914 | chr7:52778583:C:T | - | 0.090798546442322 | 0.0285101983327423 | LGG | Male-baised eQTL |
| rs17683977 | chr7:52785147:G:A | - | 0.090798546442322 | 0.0285101983327423 | LGG | Male-baised eQTL |
| rs55901705 | chr7:52759260:G:T | - | 0.0898838589751887 | 0.0326976894851689 | LGG | Male-baised eQTL |
| rs77915711 | chr7:52736121:G:C | - | 0.0882576489222864 | 0.0339456849444674 | LGG | Male-baised eQTL |
| rs116849600 | chr7:52737595:C:T | - | 0.0882576489222864 | 0.0339456849444674 | LGG | Male-baised eQTL |
| rs76055955 | chr7:52739191:A:T | - | 0.0882576489222864 | 0.0339456849444674 | LGG | Male-baised eQTL |
| rs1919535 | chr7:52743555:G:A | - | 0.0882576489222864 | 0.0339456849444674 | LGG | Male-baised eQTL |
| rs11767796 | chr7:54824262:T:C | - | 0.0383899907248254 | 0.0351118387199988 | LGG | Male-baised eQTL |
| rs35823199 | chr7:54823171:C:T | - | 0.0381258567245574 | 0.0439574889999832 | LGG | Male-baised eQTL |
| rs34618200 | chr7:54831612:A:T | - | 0.037209328251993 | 0.047639688451756 | LGG | Male-baised eQTL |
| rs12538089 | chr7:54821721:T:C | - | 0.0378653501842873 | 0.0478084896378519 | LGG | Male-baised eQTL |
| rs66780336 | chr7:47701121:C:A | - | 0.0381808525559353 | 0.0298267201632823 | KIRC | Male-baised eQTL |
| rs67344873 | chr7:47700653:T:C | - | 0.0375810140343856 | 0.0350780339048606 | KIRC | Male-baised eQTL |
| rs67853780 | chr7:47700868:C:T | - | 0.0375810140343856 | 0.0350780339048606 | KIRC | Male-baised eQTL |
| rs66979603 | chr7:47700915:G:A | - | 0.0375810140343856 | 0.0350780339048606 | KIRC | Male-baised eQTL |
| rs73107278 | chr7:47700944:C:A | - | 0.0375810140343856 | 0.0350780339048606 | KIRC | Male-baised eQTL |
| rs116924468 | chr7:47700968:A:G | - | 0.0375810140343856 | 0.0350780339048606 | KIRC | Male-baised eQTL |
| rs10245342 | chr7:64627050:A:G | - | 0.0371760282635518 | 0.00626535909009104 | BLCA | Male-baised eQTL |
| rs6460204 | chr7:64883223:T:C | - | -0.0606613282352645 | 0.024072811210604 | BLCA | Male-baised eQTL |
| rs6460207 | chr7:64888699:G:C | - | -0.0606613282352645 | 0.024072811210604 | BLCA | Male-baised eQTL |
| rs74622139 | chr7:64843888:G:A | - | -0.0466509841210955 | 0.0432141805337094 | BLCA | Male-baised eQTL |
| rs146868961 | chr7:54501648:G:A | - | 0.134754741067968 | 3.11134872697168e-05 | LUAD | Male-baised eQTL |
| rs73395815 | chr7:54394945:T:C | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs186867698 | chr7:54395423:A:T | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs184332427 | chr7:54395479:T:G | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs73395819 | chr7:54398205:T:C | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs112469387 | chr7:54401076:G:A | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs17172337 | chr7:54401795:C:G | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs73395889 | chr7:54407832:T:C | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs73395890 | chr7:54409066:T:C | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs73395897 | chr7:54411262:T:C | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs73395898 | chr7:54411334:A:G | - | 0.1183463788233 | 8.41302869245573e-05 | LUAD | Male-baised eQTL |
| rs142336730 | chr7:54397539:T:C | - | 0.118253396611561 | 8.67113099301004e-05 | LUAD | Male-baised eQTL |
| rs494536 | chr7:54486359:A:G | - | 0.117201389011026 | 8.87122542913307e-05 | LUAD | Male-baised eQTL |
| rs73395900 | chr7:54411604:C:T | - | 0.118124886608978 | 8.9787497491827e-05 | LUAD | Male-baised eQTL |
| rs6952229 | chr7:54416412:A:G | - | 0.118124886608978 | 8.9787497491827e-05 | LUAD | Male-baised eQTL |
| rs73393989 | chr7:54381161:G:A | - | 0.118081712472879 | 9.20177903176196e-05 | LUAD | Male-baised eQTL |
| rs73391881 | chr7:54352986:A:G | - | 0.112867200917301 | 0.000170141899930744 | LUAD | Male-baised eQTL |
| rs78205168 | chr7:54370753:G:T | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs1080137 | chr7:54371805:A:G | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs10428906 | chr7:54375092:T:C | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs112985282 | chr7:54376047:C:T | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs10428994 | chr7:54376188:G:A | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs73393982 | chr7:54378905:T:A | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs73393988 | chr7:54380723:C:T | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs73393992 | chr7:54383649:G:A | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs73393996 | chr7:54385720:G:T | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs73394001 | chr7:54387391:A:G | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs61142952 | chr7:54389287:C:T | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs112100535 | chr7:54389708:C:T | - | 0.113729197683999 | 0.000193309327328643 | LUAD | Male-baised eQTL |
| rs73395807 | chr7:54390526:A:G | - | 0.110123448593851 | 0.000337446493606088 | LUAD | Male-baised eQTL |
| rs113791324 | chr7:54390935:T:C | - | 0.110123448593851 | 0.000337446493606088 | LUAD | Male-baised eQTL |
| rs571748 | chr7:54487700:G:A | - | 0.10587218009534 | 0.000537910563344705 | LUAD | Male-baised eQTL |
| rs596738 | chr7:54493018:G:A | - | 0.10587218009534 | 0.000537910563344705 | LUAD | Male-baised eQTL |
| rs73403205 | chr7:54483413:C:T | - | 0.111689864398447 | 0.000652811660493554 | LUAD | Male-baised eQTL |
| rs73403206 | chr7:54483474:G:A | - | 0.108077195022443 | 0.00104264050433372 | LUAD | Male-baised eQTL |
| rs17172333 | chr7:54361257:A:C | - | 0.0985096049586973 | 0.00139482805406852 | LUAD | Male-baised eQTL |
| rs73391899 | chr7:54362153:G:T | - | 0.0985096049586973 | 0.00139482805406852 | LUAD | Male-baised eQTL |
| rs73391901 | chr7:54362545:T:C | - | 0.0985096049586973 | 0.00139482805406852 | LUAD | Male-baised eQTL |
| rs7805217 | chr7:54369275:G:A | - | 0.0985096049586973 | 0.00139482805406852 | LUAD | Male-baised eQTL |
| rs480777 | chr7:54490704:G:A | - | 0.0907051690288971 | 0.00348995699026512 | LUAD | Male-baised eQTL |
| rs34477367 | chr7:56030574:C:G | - | 0.0929246899398141 | 0.00738592475429271 | LUAD | Male-baised eQTL |
| rs491461 | chr7:49816699:A:G | - | -0.0718413920933282 | 0.014992980671656 | LUAD | Male-baised eQTL |
| rs34319969 | chr7:56026933:C:T | - | 0.081729193192316 | 0.0237512096416158 | LUAD | Male-baised eQTL |
| rs36049923 | chr7:56030507:C:A | - | 0.081729193192316 | 0.0237512096416158 | LUAD | Male-baised eQTL |
| rs13228321 | chr7:56009461:G:C | - | 0.078888643638138 | 0.0262392399588163 | LUAD | Male-baised eQTL |
| rs9656599 | chr7:49823172:G:A | - | -0.0692597874639962 | 0.0269102522153772 | LUAD | Male-baised eQTL |
| rs1483797 | chr7:49823351:G:A | - | -0.0692597874639962 | 0.0269102522153772 | LUAD | Male-baised eQTL |
| rs4948004 | chr7:55287077:T:C | - | 0.0728120592909665 | 0.0377289271782701 | LUAD | Male-baised eQTL |
| rs73391840 | chr7:54342514:A:G | - | 0.0859642663380367 | 0.0450485680963938 | LUAD | Male-baised eQTL |
| rs671767 | chr7:54527637:C:T | - | 0.0663295872656196 | 0.0497640453808865 | LUAD | Male-baised eQTL |
| rs58464352 | chr7:49645479:C:T | - | 0.0838470685127559 | 0.000339739798727949 | COAD | Male-baised eQTL |
| rs145800823 | chr7:49652453:A:C | - | 0.0822299658379135 | 0.000407284658675981 | COAD | Male-baised eQTL |
| rs61282811 | chr7:49661046:T:A | - | 0.0877080722326711 | 0.000651322275299127 | COAD | Male-baised eQTL |
| rs115613048 | chr7:49643176:A:T | - | 0.0855849713325229 | 0.000807710795561052 | COAD | Male-baised eQTL |
| rs148745454 | chr7:49664181:T:G | - | 0.084066593285013 | 0.000887159025570496 | COAD | Male-baised eQTL |
| rs141458868 | chr7:49650075:A:G | - | 0.0838451800311788 | 0.000930983306287628 | COAD | Male-baised eQTL |
| rs55939748 | chr7:49642735:G:C | - | 0.081793021026126 | 0.0014923232743552 | COAD | Male-baised eQTL |
| rs73343914 | chr7:49643165:A:G | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs58694095 | chr7:49643578:T:C | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs73343917 | chr7:49643668:G:A | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs61090971 | chr7:49643873:T:C | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs7807208 | chr7:49643946:T:C | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs59867796 | chr7:49644781:G:T | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs60639449 | chr7:49644794:C:G | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs59672568 | chr7:49645875:G:A | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs7782750 | chr7:49646923:A:T | - | 0.0735346822405667 | 0.00172485562605412 | COAD | Male-baised eQTL |
| rs73343919 | chr7:49643837:C:A | - | 0.0791212857877626 | 0.00172773557275239 | COAD | Male-baised eQTL |
| rs138409752 | chr7:49647141:G:A | - | 0.0791212857877626 | 0.00172773557275239 | COAD | Male-baised eQTL |
| rs73343936 | chr7:49647734:C:T | - | 0.0791212857877626 | 0.00172773557275239 | COAD | Male-baised eQTL |
| rs73343938 | chr7:49647931:T:A | - | 0.0791212857877626 | 0.00172773557275239 | COAD | Male-baised eQTL |
| rs376042553 | chr7:49653598:A:G | - | 0.0777108029769795 | 0.00191221907607329 | COAD | Male-baised eQTL |
| rs191734204 | chr7:49654398:A:C | - | 0.0777108029769795 | 0.00191221907607329 | COAD | Male-baised eQTL |
| rs1108270 | chr7:54796943:A:G | - | 0.0421328896004153 | 0.0180142473837175 | COAD | Male-baised eQTL |
| rs1112565 | chr7:54796379:A:G | - | 0.0414275393721093 | 0.0214545725710064 | COAD | Male-baised eQTL |
| rs1108433 | chr7:54804591:C:T | - | 0.0391059686483936 | 0.0322986391689368 | COAD | Male-baised eQTL |
| rs1108434 | chr7:54804701:C:T | - | 0.0391059686483936 | 0.0322986391689368 | COAD | Male-baised eQTL |
| rs2037795 | chr7:45346521:C:T | - | 0.0768903792526835 | 0.0324972709793761 | COAD | Male-baised eQTL |
| rs6944408 | chr7:54795253:G:A | - | 0.0402487021022528 | 0.0329055806810334 | COAD | Male-baised eQTL |
| rs4947940 | chr7:54799482:C:T | - | 0.0389582644556616 | 0.0331101522787486 | COAD | Male-baised eQTL |
| rs7798440 | chr7:54804426:C:T | - | 0.0387111204952536 | 0.0347792301611147 | COAD | Male-baised eQTL |
| rs67121927 | chr7:54794540:C:T | - | 0.0398030747023625 | 0.0356565520202047 | COAD | Male-baised eQTL |
| rs11771485 | chr7:51819924:T:C | - | 0.0574592378052848 | 0.0367122576023373 | COAD | Male-baised eQTL |
| rs9656664 | chr7:50594275:A:G | - | 0.057067900124736 | 0.0374428740902234 | COAD | Male-baised eQTL |
| rs146082648 | chr7:51807220:T:A | - | 0.0568325584533709 | 0.0379090358031892 | COAD | Male-baised eQTL |
| rs1230541 | chr7:52726505:T:A | - | 0.0334823855005759 | 0.0380206748564914 | COAD | Male-baised eQTL |
| rs113769262 | chr7:54794814:G:A | - | 0.0384420807500797 | 0.0431869690957736 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000146648 |
| CpG Site: cg17319788 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.374605368317063 | |
 | Gene ID: ENSG00000146648 |
| CpG Site: cg23757825 | |
| Position to Gene: gene | |
| Male Effect: -0.255514800347091 | |
| Female Effect: - | |
 | Gene ID: ENSG00000146648 |
| CpG Site: cg17319788 | |
| Position to Gene: gene | |
| Male Effect: -0.180962257880625 | |
| Female Effect: - | |
 | Gene ID: ENSG00000146648 |
| CpG Site: cg16956218 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.461193984691813 | |
 | Gene ID: ENSG00000146648 |
| CpG Site: cg02166842 | |
| Position to Gene: gene | |
| Male Effect: -0.121866297532572 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg23757825 | chr7:55024578 | gene | -0.255514800347091 | 1.34056407337889e-06 | -0.3815293759865529 | 5.794755684733252e-09 | LIHC |
| cg17319788 | chr7:55053708 | gene | -0.180962257880625 | 1.6435888279886e-07 | -0.3671936979774159 | 3.0975406304954726e-10 | LUSC |
| cg02166842 | chr7:55111778 | gene | -0.121866297532572 | 2.6649807938412e-08 | -0.331635747432553 | 6.762680177709543e-11 | HNSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg17319788 | chr7:55053708 | gene | -0.374605368317063 | 7.15206600913027e-10 | -0.41658551410236205 | 3.9885166229193634e-12 | LUAD |
| cg16956218 | chr7:55250717 | gene | -0.461193984691813 | 7.2016835121593e-08 | -0.6127863317455517 | 3.232035752939924e-11 | LUSC |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of EGFR |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000146648 | EGFR | C0001418 | Adenocarcinoma | 5 | CTD_human |
| ENSG00000146648 | EGFR | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| ENSG00000146648 | EGFR | C0003865 | Arthritis, Adjuvant-Induced | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0005396 | Bile Duct Neoplasms | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0005684 | Malignant neoplasm of urinary bladder | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0005695 | Bladder Neoplasm | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0006142 | Malignant neoplasm of breast | 6 | CTD_human |
| ENSG00000146648 | EGFR | C0007097 | Carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0007102 | Malignant tumor of colon | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0007113 | Rectal Carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0007131 | Non-Small Cell Lung Carcinoma | 16 | CTD_human |
| ENSG00000146648 | EGFR | C0007137 | Squamous cell carcinoma | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0007193 | Cardiomyopathy, Dilated | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0007873 | Uterine Cervical Neoplasm | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0009375 | Colonic Neoplasms | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0009402 | Colorectal Carcinoma | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0009404 | Colorectal Neoplasms | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0011603 | Dermatitis | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0014175 | Endometriosis | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0014859 | Esophageal Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0016978 | gallbladder neoplasm | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0017636 | Glioblastoma | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0018671 | Head and Neck Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0018675 | Head Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0021655 | Insulin Resistance | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0022660 | Kidney Failure, Acute | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0024121 | Lung Neoplasms | 7 | CTD_human |
| ENSG00000146648 | EGFR | C0024623 | Malignant neoplasm of stomach | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0024668 | Mammary Neoplasms, Experimental | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0024809 | Marijuana Abuse | 1 | PSYGENET |
| ENSG00000146648 | EGFR | C0025500 | Mesothelioma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0027439 | Nasopharyngeal Neoplasms | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0027533 | Neck Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0027626 | Neoplasm Invasiveness | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0027627 | Neoplasm Metastasis | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0027643 | Neoplasm Recurrence, Local | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0029463 | Osteosarcoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0030297 | Pancreatic Neoplasm | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0030354 | Papilloma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0032580 | Adenomatous Polyposis Coli | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0033578 | Prostatic Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0034885 | Rectal Neoplasms | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0038356 | Stomach Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0041696 | Unipolar Depression | 1 | PSYGENET |
| ENSG00000146648 | EGFR | C0085548 | Autosomal Recessive Polycystic Kidney Disease | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0085762 | Alcohol abuse | 1 | PSYGENET |
| ENSG00000146648 | EGFR | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0152013 | Adenocarcinoma of lung (disorder) | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0153452 | Malignant neoplasm of gallbladder | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0205641 | Adenocarcinoma, Basal Cell | 5 | CTD_human |
| ENSG00000146648 | EGFR | C0205642 | Adenocarcinoma, Oxyphilic | 5 | CTD_human |
| ENSG00000146648 | EGFR | C0205643 | Carcinoma, Cribriform | 5 | CTD_human |
| ENSG00000146648 | EGFR | C0205644 | Carcinoma, Granular Cell | 5 | CTD_human |
| ENSG00000146648 | EGFR | C0205645 | Adenocarcinoma, Tubular | 5 | CTD_human |
| ENSG00000146648 | EGFR | C0205696 | Anaplastic carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0205697 | Carcinoma, Spindle-Cell | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0205698 | Undifferentiated carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0205699 | Carcinomatosis | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0205874 | Papilloma, Squamous Cell | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0205875 | Papillomatosis | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0206686 | Adrenocortical carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0206698 | Cholangiocarcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0235874 | Disease Exacerbation | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0238301 | Cancer of Nasopharynx | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0242379 | Malignant neoplasm of lung | 7 | CTD_human |
| ENSG00000146648 | EGFR | C0263454 | Chloracne | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0269102 | Endometrioma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0278996 | Malignant Head and Neck Neoplasm | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0334588 | Giant Cell Glioblastoma | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0345905 | Intrahepatic Cholangiocarcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0346647 | Malignant neoplasm of pancreas | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0376358 | Malignant neoplasm of prostate | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0546837 | Malignant neoplasm of esophagus | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0678222 | Breast Carcinoma | 6 | CTD_human |
| ENSG00000146648 | EGFR | C0740277 | Bile duct carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0746787 | Cancer of Neck | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0751177 | Cancer of Head | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0887900 | Upper Aerodigestive Tract Neoplasms | 3 | CTD_human |
| ENSG00000146648 | EGFR | C0919267 | ovarian neoplasm | 2 | CTD_human |
| ENSG00000146648 | EGFR | C0920563 | Insulin Sensitivity | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0971858 | Arthritis, Collagen-Induced | 1 | CTD_human |
| ENSG00000146648 | EGFR | C0993582 | Arthritis, Experimental | 1 | CTD_human |
| ENSG00000146648 | EGFR | C1140680 | Malignant neoplasm of ovary | 2 | CTD_human |
| ENSG00000146648 | EGFR | C1257925 | Mammary Carcinoma, Animal | 1 | CTD_human |
| ENSG00000146648 | EGFR | C1257931 | Mammary Neoplasms, Human | 6 | CTD_human |
| ENSG00000146648 | EGFR | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
| ENSG00000146648 | EGFR | C1449563 | Cardiomyopathy, Familial Idiopathic | 1 | CTD_human |
| ENSG00000146648 | EGFR | C1458155 | Mammary Neoplasms | 6 | CTD_human |
| ENSG00000146648 | EGFR | C1565662 | Acute Kidney Insufficiency | 1 | CTD_human |
| ENSG00000146648 | EGFR | C1621958 | Glioblastoma Multiforme | 3 | CTD_human |
| ENSG00000146648 | EGFR | C1708349 | Hereditary Diffuse Gastric Cancer | 3 | CTD_human |
| ENSG00000146648 | EGFR | C2239176 | Liver carcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C2609414 | Acute kidney injury | 1 | CTD_human |
| ENSG00000146648 | EGFR | C2713442 | Polyposis, Adenomatous Intestinal | 1 | CTD_human |
| ENSG00000146648 | EGFR | C2713443 | Familial Intestinal Polyposis | 1 | CTD_human |
| ENSG00000146648 | EGFR | C3805278 | Extrahepatic Cholangiocarcinoma | 1 | CTD_human |
| ENSG00000146648 | EGFR | C4015130 | INFLAMMATORY SKIN AND BOWEL DISEASE, NEONATAL, 2 | 1 | CTD_human |
| ENSG00000146648 | EGFR | C4048328 | cervical cancer | 3 | CTD_human |
| ENSG00000146648 | EGFR | C4704874 | Mammary Carcinoma, Human | 6 | CTD_human |
