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Gene: ENSG00000146197 |
Summary for SCUBE3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000146197 | Gene symbol | SCUBE3 |
| Gene name | signal peptide, CUB domain and EGF like domain containing 3 | |
| HGNC | 13655 | |
| Entrez ID | 222663 | |
| Gene type | protein_coding | |
| Synonyms | SCUBE3|FLJ34743 | |
| UniProtAcc | Q8IX30 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SCUBE3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SCUBE3 | 3.40e+02 | 1.26e+00 | 2.24e-01 | 5.65e+00 | 1.59e-08 | 1.49e-06 | HNSC |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SCUBE3 | 3.76e+02 | 2.76e+00 | 4.30e-01 | 6.41e+00 | 1.46e-10 | 9.63e-10 | HNSC |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SCUBE3 | 1.31e+03 | 2.88e+00 | 1.86e-01 | 1.55e+01 | 3.65e-54 | 4.20e-53 | BRCA |
Top |
Sex-biased somatic mutation for SCUBE3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SCUBE3 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| READ | cg00347904 | chr6:35214731 | CGI:chr6:35213318-35214770 | promoter,gene body | 5.78e-01 | 4.31e-01 | 2.25e+00 | 2.45e-02 | 3.93e-02 | 1.48e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg00347904 | chr6:35214731 | CGI:chr6:35213318-35214770 | promoter,gene body | 2.50e-01 | 8.00e-02 | 2.73e+00 | 6.30e-03 | 9.71e-03 | 1.70e-01 |
| LUSC | cg17510121 | chr6:35215133 | CGI:chr6:35213318-35214770 | promoter,gene body | 7.15e-01 | 6.11e-01 | 2.21e+00 | 2.72e-02 | 3.05e-02 | 1.04e-01 |
| COAD | cg21604042 | chr6:35213624 | CGI:chr6:35213318-35214770 | promoter | 3.20e-01 | 1.47e-01 | 2.89e+00 | 3.84e-03 | 6.68e-03 | 1.73e-01 |
| BLCA | cg00347904 | chr6:35214731 | CGI:chr6:35213318-35214770 | promoter,gene body | 2.24e-01 | 7.72e-02 | 2.80e+00 | 5.12e-03 | 8.29e-03 | 1.47e-01 |
| BLCA | cg08799655 | chr6:35215613 | CGI:chr6:35213318-35214770 | promoter,gene body | 8.66e-01 | 7.52e-01 | 3.64e+00 | 2.75e-04 | 8.40e-04 | 1.14e-01 |
| ESCA | cg17510121 | chr6:35215133 | CGI:chr6:35213318-35214770 | promoter,gene body | 7.32e-01 | 5.30e-01 | 2.71e+00 | 6.73e-03 | 3.51e-02 | 2.03e-01 |
| CHOL | cg27426442 | chr6:35213336 | CGI:chr6:35213318-35214770 | promoter | 7.31e-01 | 5.78e-01 | 2.65e+00 | 7.96e-03 | 1.92e-02 | 1.53e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg13364903 | chr6:35213771 | CGI:chr6:35213318-35214770 | promoter | 1.36e-01 | 3.64e-02 | 6.26e+00 | 3.94e-10 | 9.88e-10 | 1.00e-01 |
| BRCA | cg00347904 | chr6:35214731 | CGI:chr6:35213318-35214770 | promoter,gene body | 3.40e-01 | 9.51e-02 | 9.32e+00 | 1.16e-20 | 6.66e-20 | 2.45e-01 |
| BRCA | cg21604042 | chr6:35213624 | CGI:chr6:35213318-35214770 | promoter | 3.63e-01 | 1.69e-01 | 9.63e+00 | 6.11e-22 | 3.91e-21 | 1.94e-01 |
| HNSC | cg13364903 | chr6:35213771 | CGI:chr6:35213318-35214770 | promoter | 1.45e-01 | 3.20e-02 | 2.33e+00 | 1.98e-02 | 2.74e-02 | 1.13e-01 |
| KIRP | cg27426442 | chr6:35213336 | CGI:chr6:35213318-35214770 | promoter | 7.29e-01 | 5.98e-01 | 2.87e+00 | 4.17e-03 | 9.48e-03 | 1.31e-01 |
| KIRP | cg00347904 | chr6:35214731 | CGI:chr6:35213318-35214770 | promoter,gene body | 1.92e-01 | 6.58e-02 | 2.79e+00 | 5.34e-03 | 1.11e-02 | 1.26e-01 |
| KIRP | cg21604042 | chr6:35213624 | CGI:chr6:35213318-35214770 | promoter | 2.72e-01 | 1.32e-01 | 2.96e+00 | 3.07e-03 | 7.80e-03 | 1.40e-01 |
| KIRP | cg08799655 | chr6:35215613 | CGI:chr6:35213318-35214770 | promoter,gene body | 8.61e-01 | 7.31e-01 | 3.51e+00 | 4.41e-04 | 2.42e-03 | 1.29e-01 |
Top |
Exon skipping events with PSI in TCGA for SCUBE3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for SCUBE3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for SCUBE3 |
| TFs related to SCUBE3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LAML | BARX2 | SCUBE3 | 5.33e+00 | 9.88e-01 | 4.39e+00 | 9.22e-03 | Male-biased |
| LAML | ZNF225 | SCUBE3 | 4.56e+00 | 9.82e-01 | 3.63e+00 | 9.43e-03 | Male-biased |
| PCPG | BARX2 | SCUBE3 | 4.48e+00 | 9.85e-01 | 3.60e+00 | 7.10e-03 | Male-biased |
| UVM | ZNF320 | SCUBE3 | 4.00e+00 | 1.36e-02 | 5.15e+00 | 9.81e-01 | Female-biased |
| SCUBE3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SCUBE3 |
| RBPs related to ES in SCUBE3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SCUBE3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000146197 | LINC00839,hsa-mir-454,SCUBE3 | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000146197 | MIAT,hsa-mir-642a,SCUBE3 | Female-specific ceRNA | TCGA-LIHC |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs112417354 | chr6:31482790:G:A | - | 0.153991118830172 | 0.000845786972472465 | SARC | Female-baised eQTL |
| rs113551020 | chr6:31489063:T:C | - | 0.153991118830172 | 0.000845786972472465 | SARC | Female-baised eQTL |
| rs77349273 | chr6:31461210:C:T | - | 0.133620637859469 | 0.00452671382411571 | SARC | Female-baised eQTL |
| rs75640364 | chr6:31465789:G:C | - | 0.133620637859469 | 0.00452671382411571 | SARC | Female-baised eQTL |
| rs79501286 | chr6:31475135:G:A | - | 0.133664333498041 | 0.00453727439982628 | SARC | Female-baised eQTL |
| rs17200593 | chr6:31477699:G:A | - | 0.128352144312528 | 0.00714737436923291 | SARC | Female-baised eQTL |
| rs17206973 | chr6:31477787:C:T | - | 0.128352144312528 | 0.00714737436923291 | SARC | Female-baised eQTL |
| rs75303729 | chr6:31479710:G:A | - | 0.128272854886212 | 0.00727791485987293 | SARC | Female-baised eQTL |
| rs28732082 | chr6:31036744:G:A | - | 0.126575318638824 | 0.0029738677602333 | LUSC | Female-baised eQTL |
| rs28732087 | chr6:31044773:C:T | - | 0.126575318638824 | 0.0029738677602333 | LUSC | Female-baised eQTL |
| rs13194580 | chr6:31017238:C:T | - | 0.110129869734807 | 0.00512705135520273 | LUSC | Female-baised eQTL |
| rs9391701 | chr6:31015486:G:A | - | 0.10974064968461 | 0.00540971859042474 | LUSC | Female-baised eQTL |
| rs3869096 | chr6:31016627:T:G | - | 0.10974064968461 | 0.00540971859042474 | LUSC | Female-baised eQTL |
| rs28732089 | chr6:31048110:A:G | - | 0.118738136241133 | 0.00642886618250237 | LUSC | Female-baised eQTL |
| rs9378112 | chr6:31011275:C:T | - | 0.106594569368346 | 0.0066310301795564 | LUSC | Female-baised eQTL |
| rs9391700 | chr6:31011301:G:A | - | 0.106594569368346 | 0.0066310301795564 | LUSC | Female-baised eQTL |
| rs9378113 | chr6:31011321:C:T | - | 0.106594569368346 | 0.0066310301795564 | LUSC | Female-baised eQTL |
| rs9378151 | chr6:31011395:C:A | - | 0.106594569368346 | 0.0066310301795564 | LUSC | Female-baised eQTL |
| rs9394025 | chr6:31011702:C:T | - | 0.106594569368346 | 0.0066310301795564 | LUSC | Female-baised eQTL |
| rs9380204 | chr6:31012156:T:C | - | 0.106594569368346 | 0.0066310301795564 | LUSC | Female-baised eQTL |
| rs113657606 | chr6:26160785:C:T | - | 0.121355383184783 | 0.00704327694510451 | LUSC | Female-baised eQTL |
| rs140058581 | chr6:26169042:A:G | - | 0.121355383184783 | 0.00704327694510451 | LUSC | Female-baised eQTL |
| rs9368652 | chr6:31017226:A:G | - | 0.105316425163445 | 0.00869027408175458 | LUSC | Female-baised eQTL |
| rs3871466 | chr6:31015906:T:C | - | 0.104921028126884 | 0.00918008784029729 | LUSC | Female-baised eQTL |
| rs9348846 | chr6:31016941:C:G | - | 0.104921028126884 | 0.00918008784029729 | LUSC | Female-baised eQTL |
| rs3873343 | chr6:31001550:C:T | - | 0.105678518178141 | 0.0104385994060952 | LUSC | Female-baised eQTL |
| rs2894050 | chr6:31001580:G:T | - | 0.105678518178141 | 0.0104385994060952 | LUSC | Female-baised eQTL |
| rs9366764 | chr6:31012016:G:A | - | 0.102110032326028 | 0.0107978251921965 | LUSC | Female-baised eQTL |
| rs4713407 | chr6:31013195:C:T | - | 0.102110032326028 | 0.0107978251921965 | LUSC | Female-baised eQTL |
| rs13198748 | chr6:31379772:C:T | - | 0.108895688316013 | 0.0190195597069637 | LUSC | Female-baised eQTL |
| rs115378916 | chr6:31379991:A:T | - | 0.108895688316013 | 0.0190195597069637 | LUSC | Female-baised eQTL |
| rs28732083 | chr6:31040553:T:C | - | 0.1022984268442 | 0.0205169431217023 | LUSC | Female-baised eQTL |
| rs28732084 | chr6:31043406:T:C | - | 0.1022984268442 | 0.0205169431217023 | LUSC | Female-baised eQTL |
| rs28732086 | chr6:31043625:T:A | - | 0.1022984268442 | 0.0205169431217023 | LUSC | Female-baised eQTL |
| rs28894977 | chr6:31035924:T:C | - | 0.1021601047182 | 0.0210404300083003 | LUSC | Female-baised eQTL |
| rs117486637 | chr6:31358156:T:C | - | 0.102351067588413 | 0.0330164640255463 | LUSC | Female-baised eQTL |
| rs35267732 | chr6:31359002:T:A | - | 0.102351067588413 | 0.0330164640255463 | LUSC | Female-baised eQTL |
| rs116579023 | chr6:31363918:C:A | - | 0.102351067588413 | 0.0330164640255463 | LUSC | Female-baised eQTL |
| rs4463302 | chr6:31375890:T:C | - | 0.102351067588413 | 0.0330164640255463 | LUSC | Female-baised eQTL |
| rs13202464 | chr6:31376806:A:G | - | 0.102351067588413 | 0.0330164640255463 | LUSC | Female-baised eQTL |
| rs28626544 | chr6:31374398:A:G | - | 0.102237894985236 | 0.0336767438385635 | LUSC | Female-baised eQTL |
| rs35863921 | chr6:44641073:A:G | - | 0.100568958734841 | 0.0380779209062046 | LUSC | Female-baised eQTL |
| rs73440405 | chr6:44641382:C:T | - | 0.100568958734841 | 0.0380779209062046 | LUSC | Female-baised eQTL |
| rs34881204 | chr6:44641855:T:C | - | 0.100568958734841 | 0.0380779209062046 | LUSC | Female-baised eQTL |
| rs28732085 | chr6:31043501:C:G | - | 0.0899664200614572 | 0.0440738649221947 | LUSC | Female-baised eQTL |
| rs2395769 | chr6:41256457:A:G | - | -0.0823135170160585 | 0.0488218394056814 | LUSC | Female-baised eQTL |
| rs2263333 | chr6:41259190:C:T | - | -0.0823135170160585 | 0.0488218394056814 | LUSC | Female-baised eQTL |
| rs6920532 | chr6:43825693:T:C | - | -0.0523839000319386 | 0.0236965209965885 | LUAD | Female-baised eQTL |
| rs9470259 | chr6:36368266:C:G | - | 0.0595700973916719 | 0.0357479562000196 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs58177962 | chr6:38544527:G:A | - | 0.149406179743256 | 0.0256050286697066 | SARC | Male-baised eQTL |
| rs78142593 | chr6:42095873:C:T | - | 0.0932144218445725 | 0.00102013278105883 | LUAD | Male-baised eQTL |
| rs28780107 | chr6:30487172:C:T | - | 0.104570185138786 | 0.00943431486221762 | LUAD | Male-baised eQTL |
| rs6923796 | chr6:42109778:T:C | - | 0.0762752602613876 | 0.0128212279757021 | LUAD | Male-baised eQTL |
| rs11968604 | chr6:37839231:A:T | - | 0.0712570281991119 | 0.0203427854433504 | LUAD | Male-baised eQTL |
| rs11970017 | chr6:37841394:A:G | - | 0.0712570281991119 | 0.0203427854433504 | LUAD | Male-baised eQTL |
| rs11970145 | chr6:37841943:A:G | - | 0.0712570281991119 | 0.0203427854433504 | LUAD | Male-baised eQTL |
| rs16890194 | chr6:37845507:T:C | - | 0.0712570281991119 | 0.0203427854433504 | LUAD | Male-baised eQTL |
| rs34611895 | chr6:37854008:A:G | - | 0.0712570281991119 | 0.0203427854433504 | LUAD | Male-baised eQTL |
| rs2645115 | chr6:38027451:A:G | - | -0.0711973772713048 | 0.0205780328376133 | LUAD | Male-baised eQTL |
| rs2842498 | chr6:38030424:A:G | - | -0.0711973772713048 | 0.0205780328376133 | LUAD | Male-baised eQTL |
| rs7757560 | chr6:38039711:G:A | - | -0.0711973772713048 | 0.0205780328376133 | LUAD | Male-baised eQTL |
| rs35248825 | chr6:37865318:A:G | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs13207526 | chr6:37869145:C:G | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs7760770 | chr6:37869916:C:T | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs141753844 | chr6:37874313:C:T | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs6912250 | chr6:37874804:G:A | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs13211881 | chr6:37876048:G:A | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs74324775 | chr6:37879441:C:A | - | 0.0710921215497759 | 0.0210940230510883 | LUAD | Male-baised eQTL |
| rs6911481 | chr6:37809686:A:G | - | 0.0715347622058276 | 0.0213938132493525 | LUAD | Male-baised eQTL |
| rs56391784 | chr6:37828955:G:A | - | 0.0723219004138108 | 0.0219054338756899 | LUAD | Male-baised eQTL |
| rs7742379 | chr6:37869684:T:A | - | 0.0707499538498263 | 0.0226327242894558 | LUAD | Male-baised eQTL |
| rs9348827 | chr6:29340616:G:T | - | 0.0653675173343822 | 0.0239306641589749 | LUAD | Male-baised eQTL |
| rs78229895 | chr6:42094193:G:C | - | 0.0782898991391499 | 0.024636116038271 | LUAD | Male-baised eQTL |
| rs2645104 | chr6:38012180:G:A | - | -0.0694910206089709 | 0.0260163004560178 | LUAD | Male-baised eQTL |
| rs6918802 | chr6:37893187:C:A | - | 0.0692259408306489 | 0.0271740096200236 | LUAD | Male-baised eQTL |
| rs71569395 | chr6:37895037:G:T | - | 0.0692259408306489 | 0.0271740096200236 | LUAD | Male-baised eQTL |
| rs35953900 | chr6:37895973:G:A | - | 0.0692259408306489 | 0.0271740096200236 | LUAD | Male-baised eQTL |
| rs6910837 | chr6:37897132:A:T | - | 0.0692259408306489 | 0.0271740096200236 | LUAD | Male-baised eQTL |
| rs2645123 | chr6:37981906:C:T | - | -0.0634198836733697 | 0.04569338332971 | LUAD | Male-baised eQTL |
| rs2842516 | chr6:37953059:G:C | - | -0.0637894688102555 | 0.0486572686934649 | LUAD | Male-baised eQTL |
| rs2842514 | chr6:37944706:A:G | - | -0.0637593142807961 | 0.049091795855341 | LUAD | Male-baised eQTL |
| rs2645098 | chr6:37950144:A:T | - | -0.0637593142807961 | 0.049091795855341 | LUAD | Male-baised eQTL |
| rs2453882 | chr6:37950787:C:G | - | -0.0637593142807961 | 0.049091795855341 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000146197 |
| CpG Site: cg17510121 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.273765940336311 | |
| Female Effect: - | |
 | Gene ID: ENSG00000146197 |
| CpG Site: cg17510121 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.481591075787229 | |
| Female Effect: - | |
 | Gene ID: ENSG00000146197 |
| CpG Site: cg11562411 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.264889956656043 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg17510121 | chr6:35215133 | gene,promoter | -0.273765940336311 | 2.15310098115679e-21 | -0.6234081137882289 | 2.0771671397980677e-25 | LUAD |
| cg17510121 | chr6:35215133 | gene,promoter | -0.481591075787229 | 4.11488646539578e-17 | -0.5072481210280494 | 1.6937309285794094e-20 | SKCM |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg11562411 | chr6:35238841 | gene | -0.264889956656043 | 1.27586270485373e-06 | -0.4282010597203046 | 2.2406549613747844e-09 | SKCM |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of SCUBE3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
