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Gene: ENSG00000146038 |
Summary for DCDC2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000146038 | Gene symbol | DCDC2 |
| Gene name | doublecortin domain containing 2 | |
| HGNC | 18141 | |
| Entrez ID | 51473 | |
| Gene type | protein_coding | |
| Synonyms | DCDC2|RU2|KIAA1154|DCDC2A|NPHP19 | |
| UniProtAcc | Q9UHG0 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for DCDC2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DCDC2 | 1.61e+03 | -1.63e+00 | 2.30e-01 | -7.09e+00 | 1.39e-12 | 2.24e-10 | LIHC |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DCDC2 | 4.20e+02 | 2.99e+00 | 4.59e-01 | 6.51e+00 | 7.51e-11 | 1.11e-09 | STAD |
| DCDC2 | 1.59e+02 | 1.95e+00 | 4.65e-01 | 4.20e+00 | 2.66e-05 | 8.04e-05 | COAD |
| DCDC2 | 8.79e+03 | 4.14e+00 | 6.54e-01 | 6.33e+00 | 2.49e-10 | 3.99e-09 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DCDC2 | 2.49e+03 | 2.92e+00 | 5.00e-01 | 5.84e+00 | 5.21e-09 | 4.34e-08 | LIHC |
| DCDC2 | 5.90e+02 | -1.18e+00 | 2.01e-01 | -5.89e+00 | 3.78e-09 | 7.64e-09 | BRCA |
Top |
Sex-biased somatic mutation for DCDC2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for DCDC2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg13833328 | chr6:24356870 | CGI:chr6:24357491-24358081 | promoter,gene body | 6.75e-01 | 7.88e-01 | -3.17e+00 | 1.55e-03 | 5.04e-03 | -1.13e-01 |
| LIHC | cg08126211 | chr6:24357492 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 4.07e-01 | 5.09e-01 | -3.59e+00 | 3.37e-04 | 1.73e-03 | -1.03e-01 |
| LIHC | cg04515001 | chr6:24358008 | CGI:chr6:24357491-24358081 | UTR,promoter,exon,gene body | 4.29e-01 | 5.64e-01 | -3.74e+00 | 1.87e-04 | 1.12e-03 | -1.35e-01 |
| LIHC | cg16306115 | chr6:24358078 | CGI:chr6:24357491-24358081 | promoter | 3.98e-01 | 4.99e-01 | -3.02e+00 | 2.56e-03 | 7.11e-03 | -1.01e-01 |
| LIHC | cg07054208 | chr6:24358338 | CGI:chr6:24357491-24358081 | promoter | 4.75e-01 | 6.13e-01 | -2.18e+00 | 2.95e-02 | 3.58e-02 | -1.39e-01 |
| READ | cg04945158 | chr6:24358453 | CGI:chr6:24357491-24358081 | promoter | 6.50e-01 | 2.94e-01 | 6.09e+00 | 1.11e-09 | 8.57e-09 | 3.56e-01 |
| ESCA | cg04945158 | chr6:24358453 | CGI:chr6:24357491-24358081 | promoter | 4.24e-01 | 5.28e-01 | 2.14e+00 | 3.21e-02 | 4.47e-02 | -1.05e-01 |
| MESO | cg07054208 | chr6:24358338 | CGI:chr6:24357491-24358081 | promoter | 3.03e-01 | 4.31e-01 | -2.38e+00 | 1.71e-02 | 3.65e-02 | -1.27e-01 |
| CHOL | cg04945158 | chr6:24358453 | CGI:chr6:24357491-24358081 | promoter | 2.43e-01 | 4.34e-01 | 2.29e+00 | 2.19e-02 | 3.45e-02 | -1.91e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg21552319 | chr6:24356768 | CGI:chr6:24357491-24358081 | promoter,gene body | 4.59e-01 | 3.48e-01 | 4.11e+00 | 3.95e-05 | 9.04e-05 | 1.11e-01 |
| KIRC | cg13833328 | chr6:24356870 | CGI:chr6:24357491-24358081 | promoter,gene body | 4.73e-01 | 2.98e-01 | 5.51e+00 | 3.54e-08 | 2.07e-07 | 1.75e-01 |
| LUAD | cg21552319 | chr6:24356768 | CGI:chr6:24357491-24358081 | promoter,gene body | 6.51e-01 | 5.47e-01 | 2.17e+00 | 3.00e-02 | 3.30e-02 | 1.04e-01 |
| LUSC | cg03960072 | chr6:24357757 | CGI:chr6:24357491-24358081 | UTR,promoter,exon,gene body | 2.96e-01 | 1.42e-01 | 2.81e+00 | 4.92e-03 | 8.06e-03 | 1.54e-01 |
| LUSC | cg07791578 | chr6:24358080 | CGI:chr6:24357491-24358081 | promoter | 1.76e-01 | 3.69e-02 | 3.41e+00 | 6.38e-04 | 1.94e-03 | 1.39e-01 |
| LUSC | cg21729798 | chr6:24356850 | CGI:chr6:24357491-24358081 | promoter,gene body | 5.16e-01 | 3.46e-01 | 2.68e+00 | 7.46e-03 | 1.11e-02 | 1.70e-01 |
| LUSC | cg13833328 | chr6:24356870 | CGI:chr6:24357491-24358081 | promoter,gene body | 6.78e-01 | 5.31e-01 | 2.52e+00 | 1.17e-02 | 1.57e-02 | 1.47e-01 |
| LUSC | cg08126211 | chr6:24357492 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 3.62e-01 | 1.55e-01 | 3.68e+00 | 2.34e-04 | 1.06e-03 | 2.07e-01 |
| LUSC | cg10090650 | chr6:24357504 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 5.02e-01 | 3.10e-01 | 3.44e+00 | 5.75e-04 | 1.81e-03 | 1.93e-01 |
| LUSC | cg14069965 | chr6:24357588 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 3.89e-01 | 1.95e-01 | 3.64e+00 | 2.77e-04 | 1.16e-03 | 1.94e-01 |
| COAD | cg13833328 | chr6:24356870 | CGI:chr6:24357491-24358081 | promoter,gene body | 4.21e-01 | 5.67e-01 | -2.59e+00 | 9.64e-03 | 1.40e-02 | -1.46e-01 |
| BLCA | cg07054208 | chr6:24358338 | CGI:chr6:24357491-24358081 | promoter | 3.02e-01 | 1.86e-01 | -1.97e+00 | 4.94e-02 | 4.95e-02 | 1.16e-01 |
| LIHC | cg03960072 | chr6:24357757 | CGI:chr6:24357491-24358081 | UTR,promoter,exon,gene body | 4.73e-01 | 2.83e-01 | 4.25e+00 | 2.14e-05 | 5.32e-05 | 1.90e-01 |
| LIHC | cg27252395 | chr6:24358099 | CGI:chr6:24357491-24358081 | promoter | 4.30e-01 | 1.00e-01 | 4.24e+00 | 2.22e-05 | 5.49e-05 | 3.30e-01 |
| LIHC | cg08126211 | chr6:24357492 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 5.09e-01 | 2.56e-01 | 4.96e+00 | 7.18e-07 | 2.80e-06 | 2.54e-01 |
| LIHC | cg10090650 | chr6:24357504 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 6.30e-01 | 4.93e-01 | 3.99e+00 | 6.59e-05 | 1.43e-04 | 1.37e-01 |
| LIHC | cg14069965 | chr6:24357588 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 5.51e-01 | 3.27e-01 | 4.50e+00 | 6.95e-06 | 1.99e-05 | 2.24e-01 |
| LIHC | cg04515001 | chr6:24358008 | CGI:chr6:24357491-24358081 | UTR,promoter,exon,gene body | 5.64e-01 | 1.86e-01 | 4.45e+00 | 8.74e-06 | 2.43e-05 | 3.78e-01 |
| LIHC | cg05347898 | chr6:24358076 | CGI:chr6:24357491-24358081 | promoter | 4.76e-01 | 1.15e-01 | 4.31e+00 | 1.66e-05 | 4.25e-05 | 3.61e-01 |
| LIHC | cg16306115 | chr6:24358078 | CGI:chr6:24357491-24358081 | promoter | 4.99e-01 | 1.54e-01 | 4.56e+00 | 5.03e-06 | 1.50e-05 | 3.44e-01 |
| LIHC | cg07054208 | chr6:24358338 | CGI:chr6:24357491-24358081 | promoter | 6.13e-01 | 2.77e-01 | 4.23e+00 | 2.39e-05 | 5.85e-05 | 3.36e-01 |
| LIHC | cg04945158 | chr6:24358453 | CGI:chr6:24357491-24358081 | promoter | 7.23e-01 | 4.23e-01 | 2.97e+00 | 3.00e-03 | 4.20e-03 | 3.00e-01 |
| CHOL | cg03960072 | chr6:24357757 | CGI:chr6:24357491-24358081 | UTR,promoter,exon,gene body | 1.31e-01 | 2.70e-01 | -2.95e+00 | 3.19e-03 | 1.32e-02 | -1.39e-01 |
| CHOL | cg13833328 | chr6:24356870 | CGI:chr6:24357491-24358081 | promoter,gene body | 4.47e-01 | 8.02e-01 | -2.73e+00 | 6.38e-03 | 1.82e-02 | -3.55e-01 |
| CHOL | cg10090650 | chr6:24357504 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 2.62e-01 | 4.42e-01 | -3.10e+00 | 1.96e-03 | 1.07e-02 | -1.79e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg07791578 | chr6:24358080 | CGI:chr6:24357491-24358081 | promoter | 1.90e-01 | 5.83e-02 | 9.29e+00 | 1.50e-20 | 8.47e-20 | 1.31e-01 |
| LUAD | cg08126211 | chr6:24357492 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 2.76e-01 | 1.70e-01 | 2.46e+00 | 1.38e-02 | 1.98e-02 | 1.05e-01 |
| LUAD | cg10090650 | chr6:24357504 | CGI:chr6:24357491-24358081 | promoter,exon,CDS,gene body | 4.14e-01 | 3.07e-01 | 2.30e+00 | 2.17e-02 | 2.74e-02 | 1.06e-01 |
Top |
Exon skipping events with PSI in TCGA for DCDC2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for DCDC2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for DCDC2 |
| TFs related to DCDC2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| GBM | FOXR2 | DCDC2 | 4.22e+00 | 9.82e-01 | 2.96e+00 | 5.93e-03 | Male-biased |
| GBM | PLAG1 | DCDC2 | 2.00e+00 | 1.07e-03 | 3.88e+00 | 9.80e-01 | Female-biased |
| GBM | TFAP2A | DCDC2 | 2.43e+00 | 2.14e-03 | 4.06e+00 | 9.85e-01 | Female-biased |
| GBM | TFAP2B | DCDC2 | 2.55e+00 | 2.17e-03 | 4.18e+00 | 9.88e-01 | Female-biased |
| GBM | TFAP2C | DCDC2 | 2.46e+00 | 2.51e-03 | 4.03e+00 | 9.84e-01 | Female-biased |
| GBM | ZFP69B | DCDC2 | 2.58e+00 | 3.99e-03 | 3.97e+00 | 9.80e-01 | Female-biased |
| GBM | ZNF334 | DCDC2 | 4.53e+00 | 9.88e-01 | 3.22e+00 | 5.20e-03 | Male-biased |
| GBM | ZNF35 | DCDC2 | 4.57e+00 | 9.84e-01 | 3.47e+00 | 9.58e-03 | Male-biased |
| GBM | ZNF418 | DCDC2 | 4.20e+00 | 9.87e-01 | 2.40e+00 | 1.01e-03 | Male-biased |
| GBM | ZNF563 | DCDC2 | 2.57e+00 | 2.01e-03 | 4.23e+00 | 9.89e-01 | Female-biased |
| GBM | ZNF674 | DCDC2 | 2.58e+00 | 3.78e-03 | 4.00e+00 | 9.81e-01 | Female-biased |
| GBM | ZSCAN30 | DCDC2 | 2.04e+00 | 1.00e-03 | 3.95e+00 | 9.83e-01 | Female-biased |
| MESO | ZNF121 | DCDC2 | 2.59e+00 | 4.23e-03 | 4.11e+00 | 9.83e-01 | Female-biased |
| MESO | ZNF496 | DCDC2 | 2.60e+00 | 4.20e-03 | 4.12e+00 | 9.83e-01 | Female-biased |
| PAAD | FOXC2 | DCDC2 | 4.06e+00 | 9.85e-01 | 2.92e+00 | 1.99e-03 | Male-biased |
| PAAD | FOXL1 | DCDC2 | 4.70e+00 | 9.94e-01 | 3.49e+00 | 1.52e-03 | Male-biased |
| PAAD | FOXR2 | DCDC2 | 4.55e+00 | 9.92e-01 | 3.34e+00 | 1.41e-03 | Male-biased |
| PAAD | ZNF334 | DCDC2 | 4.89e+00 | 9.96e-01 | 3.40e+00 | 3.27e-04 | Male-biased |
| PAAD | ZNF35 | DCDC2 | 4.81e+00 | 9.89e-01 | 3.89e+00 | 6.36e-03 | Male-biased |
| PAAD | ZNF418 | DCDC2 | 4.31e+00 | 9.91e-01 | 2.80e+00 | 2.88e-04 | Male-biased |
| PAAD | ZNF879 | DCDC2 | 4.04e+00 | 9.86e-01 | 2.70e+00 | 7.05e-04 | Male-biased |
| SARC | ZNF100 | DCDC2 | 2.40e+00 | 7.22e-05 | 3.97e+00 | 9.85e-01 | Female-biased |
| SARC | ZNF30 | DCDC2 | 2.26e+00 | 7.51e-05 | 3.82e+00 | 9.80e-01 | Female-biased |
| SARC | ZNF519 | DCDC2 | 2.51e+00 | 1.35e-04 | 3.96e+00 | 9.85e-01 | Female-biased |
| SARC | ZNF571 | DCDC2 | 2.50e+00 | 1.23e-04 | 3.97e+00 | 9.85e-01 | Female-biased |
| DCDC2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for DCDC2 |
| RBPs related to ES in DCDC2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DCDC2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000146038 | AC144831.1,hsa-mir-372,DCDC2 | Tumor-specific sex-biased ceRNA | TCGA-LIHC |
| ENSG00000146038 | LINC01011,hsa-mir-454,DCDC2 | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000146038 | SNHG14,hsa-mir-454,DCDC2 | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000146038 | AC004812.2,hsa-mir-454,DCDC2 | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000146038 | MCM3AP-AS1,hsa-mir-454,DCDC2 | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000146038 | Z95331.1,hsa-mir-454,DCDC2 | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000146038 | KCNQ1OT1,hsa-mir-373,DCDC2 | Male-specific ceRNA | TCGA-STAD |
| ENSG00000146038 | KCNQ1OT1,hsa-mir-373,DCDC2 | Male-specific ceRNA | TCGA-STAD |
| ENSG00000146038 | KCNQ1OT1,hsa-mir-500b,DCDC2 | Male-specific ceRNA | TCGA-STAD |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs72837366 | chr6:23829758:C:T | - | 0.282891867238363 | 0.0278314132784019 | KIRP | Female-baised eQTL |
| rs75046260 | chr6:23789810:A:G | - | 0.251957902376983 | 0.0308187913802299 | LIHC | Female-baised eQTL |
| rs59818821 | chr6:23794641:A:G | - | 0.251821257298761 | 0.0310593026269899 | LIHC | Female-baised eQTL |
| rs376937075 | chr6:31132465:T:G | - | 0.128917665526575 | 0.0327749894058119 | STAD | Female-baised eQTL |
| rs2905760 | chr6:29958684:A:C | - | 0.087114729819583 | 0.0365129285118626 | STAD | Female-baised eQTL |
| rs12662717 | chr6:33878019:C:G | - | 0.0792695537648649 | 0.0493658056026918 | STAD | Female-baised eQTL |
| rs1807914 | chr6:22313016:C:A | - | -0.143479149939594 | 0.00207621683412759 | KIRC | Female-baised eQTL |
| rs2655418 | chr6:22322027:T:G | - | -0.133956899338349 | 0.00326593553935768 | KIRC | Female-baised eQTL |
| rs2744111 | chr6:22313667:C:G | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2744109 | chr6:22313740:G:T | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2185590 | chr6:22314293:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2744107 | chr6:22314559:C:T | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2744106 | chr6:22314797:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs718783 | chr6:22315065:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2655448 | chr6:22315375:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs1935022 | chr6:22315384:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs1883372 | chr6:22316229:A:T | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs1569544 | chr6:22316713:A:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs717157 | chr6:22317286:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs717156 | chr6:22317393:C:A | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2744103 | chr6:22318214:C:G | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2143001 | chr6:22318754:C:T | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2179333 | chr6:22318885:G:T | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2655414 | chr6:22319019:G:A | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2744100 | chr6:22319688:A:G | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2744099 | chr6:22319936:T:C | - | -0.132350474024945 | 0.00522204423704279 | KIRC | Female-baised eQTL |
| rs2473121 | chr6:22312189:T:G | - | -0.107507639008533 | 0.00730809423296306 | KIRC | Female-baised eQTL |
| rs2143002 | chr6:22318571:G:A | - | -0.127116389420408 | 0.00884415926855201 | KIRC | Female-baised eQTL |
| rs2473122 | chr6:22312058:A:G | - | -0.0996642940027248 | 0.0127316567523885 | KIRC | Female-baised eQTL |
| rs2504809 | chr6:22312170:A:C | - | -0.0996642940027248 | 0.0127316567523885 | KIRC | Female-baised eQTL |
| rs2655433 | chr6:22312033:T:C | - | -0.0973846241829709 | 0.0168953896000524 | KIRC | Female-baised eQTL |
| rs2655415 | chr6:22320093:A:G | - | -0.110681843632451 | 0.0371646599764264 | KIRC | Female-baised eQTL |
| rs13193106 | chr6:16374716:T:C | - | 0.0711351384585986 | 0.017758843949473 | LUAD | Female-baised eQTL |
| rs12199579 | chr6:17301455:A:G | - | 0.0465162789365044 | 0.0232869313988575 | LUAD | Female-baised eQTL |
| rs7752524 | chr6:25310357:A:G | - | 0.0624354647990412 | 0.0388359705556617 | LUAD | Female-baised eQTL |
| rs3890904 | chr6:29815714:T:C | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs58075773 | chr6:29816533:G:A | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs61609080 | chr6:29816766:A:C | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs115920041 | chr6:29816992:T:C | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs114181339 | chr6:29817206:G:A | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs17179017 | chr6:29817894:C:T | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs17179038 | chr6:29818181:C:G | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs17185440 | chr6:29818280:G:T | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs17185447 | chr6:29818437:C:T | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs17179066 | chr6:29818488:T:A | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs113998437 | chr6:29818569:C:T | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs115128443 | chr6:29818575:G:A | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs62394682 | chr6:29818632:C:G | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs56067910 | chr6:29818989:G:A | - | 0.0721124942759641 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs55729140 | chr6:29819755:T:G | - | 0.07197458983609 | 0.0403436803870362 | LUAD | Female-baised eQTL |
| rs55970611 | chr6:29819872:G:A | - | 0.07197458983609 | 0.0403436803870362 | LUAD | Female-baised eQTL |
| rs3873245 | chr6:29820760:C:T | - | 0.07197458983609 | 0.0403436803870362 | LUAD | Female-baised eQTL |
| rs56324548 | chr6:29821017:T:G | - | 0.07197458983609 | 0.0403436803870362 | LUAD | Female-baised eQTL |
| rs2394172 | chr6:29789023:C:T | - | 0.0660054500430204 | 0.0463755515451545 | LUAD | Female-baised eQTL |
| rs7745262 | chr6:16380141:C:T | - | 0.0638580322183545 | 0.0487343643025314 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11759478 | chr6:15351477:C:G | - | 0.100894318897822 | 0.00189942209946947 | KIRP | Male-baised eQTL |
| rs73386612 | chr6:27841001:A:T | - | 0.068899572557027 | 0.0163070356674198 | KIRP | Male-baised eQTL |
| rs707833 | chr6:15341144:G:A | - | -0.0433502742023081 | 0.0434436864605277 | KIRC | Male-baised eQTL |
| rs4122198 | chr6:29777816:T:C | - | 0.126796471111862 | 0.00101577980283859 | LUAD | Male-baised eQTL |
| rs9258303 | chr6:29775153:C:T | - | 0.133684224455598 | 0.00193983515259814 | LUAD | Male-baised eQTL |
| rs762324 | chr6:30488109:G:A | - | 0.131306856053044 | 0.00203368431451672 | LUAD | Male-baised eQTL |
| rs9258302 | chr6:29773561:T:C | - | 0.133279202709116 | 0.00207718170194627 | LUAD | Male-baised eQTL |
| rs12176594 | chr6:30469003:A:T | - | 0.120829424920873 | 0.00287847066130745 | LUAD | Male-baised eQTL |
| rs77072171 | chr6:30473416:A:G | - | 0.120829424920873 | 0.00287847066130745 | LUAD | Male-baised eQTL |
| rs9404933 | chr6:30475552:A:C | - | 0.120829424920873 | 0.00287847066130745 | LUAD | Male-baised eQTL |
| rs12174433 | chr6:30477699:G:A | - | 0.120829424920873 | 0.00287847066130745 | LUAD | Male-baised eQTL |
| rs74223639 | chr6:30479094:T:C | - | 0.120829424920873 | 0.00287847066130745 | LUAD | Male-baised eQTL |
| rs78311904 | chr6:30476340:G:A | - | 0.120481929496922 | 0.00306732302368831 | LUAD | Male-baised eQTL |
| rs61410672 | chr6:30426894:G:A | - | 0.13699963191427 | 0.00436019396370638 | LUAD | Male-baised eQTL |
| rs16897572 | chr6:30485936:C:T | - | 0.119542555833655 | 0.00731616400524027 | LUAD | Male-baised eQTL |
| rs16884319 | chr6:20959776:T:G | - | 0.116557020086009 | 0.00957948465445521 | LUAD | Male-baised eQTL |
| rs1324565 | chr6:18495502:C:T | - | -0.0881564939314014 | 0.010288297860257 | LUAD | Male-baised eQTL |
| rs1324566 | chr6:18495916:G:A | - | -0.0881564939314014 | 0.010288297860257 | LUAD | Male-baised eQTL |
| rs6906622 | chr6:18488077:T:C | - | -0.0874690134079802 | 0.0115789695984199 | LUAD | Male-baised eQTL |
| rs4716268 | chr6:18490264:A:C | - | -0.0873299095832693 | 0.0124318795267698 | LUAD | Male-baised eQTL |
| rs1359339 | chr6:18498297:T:G | - | -0.0837357735794614 | 0.0132392580987036 | LUAD | Male-baised eQTL |
| rs6928004 | chr6:18489411:G:A | - | -0.0859957130043814 | 0.0148554304644116 | LUAD | Male-baised eQTL |
| rs4716270 | chr6:18493354:T:C | - | -0.0855774987612797 | 0.0160997131916611 | LUAD | Male-baised eQTL |
| rs2057556 | chr6:18494146:C:T | - | -0.0849671976400796 | 0.0166601693103066 | LUAD | Male-baised eQTL |
| rs6899634 | chr6:18492755:A:C | - | -0.084135638453198 | 0.019856229717779 | LUAD | Male-baised eQTL |
| rs9371065 | chr6:18492899:A:T | - | -0.084135638453198 | 0.019856229717779 | LUAD | Male-baised eQTL |
| rs6920708 | chr6:18493005:C:T | - | -0.084135638453198 | 0.019856229717779 | LUAD | Male-baised eQTL |
| rs72825578 | chr6:16640059:A:G | - | 0.0728205910676099 | 0.0234815483046645 | LUAD | Male-baised eQTL |
| rs77461267 | chr6:16641149:G:C | - | 0.0737448406153064 | 0.0249795626472011 | LUAD | Male-baised eQTL |
| rs184084677 | chr6:28035444:C:T | - | 0.133588743645243 | 0.0294841078117112 | LUAD | Male-baised eQTL |
| rs1324564 | chr6:18495218:C:T | - | -0.0808298575387059 | 0.0295203628104445 | LUAD | Male-baised eQTL |
| rs7740716 | chr6:16968924:G:A | - | -0.0670508035863968 | 0.0295282432082065 | LUAD | Male-baised eQTL |
| rs17875358 | chr6:30486948:C:A | - | 0.107286462381422 | 0.0333177564337273 | LUAD | Male-baised eQTL |
| rs9380178 | chr6:30446130:C:T | - | 0.100487498374382 | 0.0405843990361496 | LUAD | Male-baised eQTL |
| rs115411850 | chr6:30428189:T:C | - | 0.100486900753282 | 0.0407018258198037 | LUAD | Male-baised eQTL |
| rs9356959 | chr6:25041763:A:G | - | 0.131773429596389 | 0.0409249255180739 | LUAD | Male-baised eQTL |
| rs9393999 | chr6:30273337:A:G | - | 0.0842298546189308 | 0.0417873774718777 | LUAD | Male-baised eQTL |
| rs2394779 | chr6:30284829:A:C | - | 0.0842298546189308 | 0.0417873774718777 | LUAD | Male-baised eQTL |
| rs9368632 | chr6:30287728:G:A | - | 0.0842298546189308 | 0.0417873774718777 | LUAD | Male-baised eQTL |
| rs78860372 | chr6:30412589:A:T | - | 0.100150990698234 | 0.042341579611805 | LUAD | Male-baised eQTL |
| rs9394000 | chr6:30298368:G:A | - | 0.0841003298913452 | 0.0424974975503263 | LUAD | Male-baised eQTL |
| rs76262765 | chr6:21099259:T:C | - | 0.132396814452796 | 0.0457176113980883 | LUAD | Male-baised eQTL |
| rs4715963 | chr6:15075626:G:C | - | 0.0647947082574325 | 0.0463946144265809 | LUAD | Male-baised eQTL |
| rs11963150 | chr6:21110478:C:G | - | 0.132070742517676 | 0.0468575214772297 | LUAD | Male-baised eQTL |
| rs4712249 | chr6:15087667:G:C | - | 0.0614339952806957 | 0.0498425810092891 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000146038 |
| CpG Site: cg23906876 | |
| Position to Gene: gene | |
| Male Effect: -0.457284940445249 | |
| Female Effect: - | |
 | Gene ID: ENSG00000146038 |
| CpG Site: cg21552319 | |
| Position to Gene: gene,promoter | |
| Male Effect: - | |
| Female Effect: -0.47709640639104 | |
 | Gene ID: ENSG00000146038 |
| CpG Site: cg22469020 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.154463489340636 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg23906876 | chr6:24324546 | gene | -0.457284940445249 | 5.32572049905985e-25 | -0.6571716065621462 | 3.1527965853770685e-26 | KIRP |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg21552319 | chr6:24356768 | gene,promoter | -0.47709640639104 | 8.51701418571968e-24 | -0.6211170138760326 | 5.701060798570093e-25 | LUAD |
| cg22469020 | chr6:24240707 | gene | -0.154463489340636 | 4.63447200412605e-05 | -0.445177944158097 | 6.946609567676728e-07 | STAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of DCDC2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000146038 | DCDC2 | C0036341 | Schizophrenia | 1 | PSYGENET |
| ENSG00000146038 | DCDC2 | C1857750 | DEAFNESS, AUTOSOMAL RECESSIVE 66 | 1 | CTD_human |
| ENSG00000146038 | DCDC2 | C4015542 | NEPHRONOPHTHISIS 19 | 1 | CTD_human |
| ENSG00000146038 | DCDC2 | C4479344 | SCLEROSING CHOLANGITIS, NEONATAL | 1 | CTD_human |
