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Gene: ENSG00000145979 |
Summary for TBC1D7 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000145979 | Gene symbol | TBC1D7 |
| Gene name | TBC1 domain family member 7 | |
| HGNC | 21066 | |
| Entrez ID | 51256 | |
| Gene type | protein_coding | |
| Synonyms | TBC1D7|dJ257A7.3|FLJ32666 | |
| UniProtAcc | Q9P0N9 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TBC1D7 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TBC1D7 | 1.03e+03 | 1.53e+00 | 2.14e-01 | 7.16e+00 | 8.30e-13 | 2.94e-11 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TBC1D7 | 1.08e+03 | 1.01e+00 | 7.06e-02 | 1.43e+01 | 3.63e-46 | 3.24e-45 | BRCA |
Top |
Sex-biased somatic mutation for TBC1D7 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for TBC1D7 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg09258965 | chr6:13329393 | CGI:chr6:13328355-13328864 | promoter | 7.37e-01 | 9.01e-01 | -3.45e+00 | 5.65e-04 | 1.79e-03 | -1.64e-01 |
| LIHC | cg09258965 | chr6:13329393 | CGI:chr6:13328355-13328864 | promoter | 6.80e-01 | 8.35e-01 | -3.92e+00 | 8.77e-05 | 1.84e-04 | -1.55e-01 |
| ESCA | cg09258965 | chr6:13329393 | CGI:chr6:13328355-13328864 | promoter | 7.84e-01 | 6.60e-01 | 2.18e+00 | 2.90e-02 | 4.34e-02 | 1.24e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for TBC1D7 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| KICH | exon_skip_456313 | 7.43e-01 | 8.48e-01 | -3.14e+00 | 1.68e-03 | 6.93e-03 | -1.05e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for TBC1D7 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for TBC1D7 |
| TFs related to TBC1D7. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ESCA | NRF1 | TBC1D7 | 4.31e+00 | 9.85e-01 | 3.53e+00 | 7.14e-03 | Male-biased |
| TBC1D7 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for TBC1D7 |
| RBPs related to ES in TBC1D7. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | FXR2 | exon_skip_456313 | 9.31e+00 | 9.44e-03 | 9.63e+00 | 9.88e-01 | Female-biased |
| READ | KHDRBS1 | exon_skip_456280 | 7.68e+00 | 9.03e-03 | 8.03e+00 | 9.83e-01 | Female-biased |
| THCA | ELAVL2 | exon_skip_456280 | 6.88e+00 | 9.81e-01 | 6.53e+00 | 4.21e-03 | Male-biased |
| THCA | KHDRBS1 | exon_skip_456280 | 8.01e+00 | 9.86e-01 | 7.68e+00 | 5.95e-03 | Male-biased |
| HNSC | KHDRBS1 | exon_skip_456280 | 8.12e+00 | 9.83e-01 | 7.76e+00 | 8.63e-03 | Male-biased |
| TBC1D7 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12214515 | chr6:18041561:T:G | - | 0.234378003129798 | 0.0479336522840343 | GBM | Female-baised eQTL |
| rs73386546 | chr6:20543664:C:G | - | 0.0832993166700905 | 0.00522201064785564 | KIRC | Female-baised eQTL |
| rs12527686 | chr6:21214307:G:A | - | 0.0558082218075721 | 0.0215660799270292 | KIRC | Female-baised eQTL |
| rs7743314 | chr6:20624008:A:G | - | 0.054541390619337 | 0.0452295419568088 | KIRC | Female-baised eQTL |
| rs16884003 | chr6:20624755:A:T | - | 0.054541390619337 | 0.0452295419568088 | KIRC | Female-baised eQTL |
| rs11966052 | chr6:16098759:A:G | - | 0.0456278011567279 | 0.00238538150526927 | LUAD | Female-baised eQTL |
| rs9969015 | chr6:16099298:G:A | - | 0.0456278011567279 | 0.00238538150526927 | LUAD | Female-baised eQTL |
| rs78406021 | chr6:16212143:G:A | - | 0.060376714111326 | 0.00456854804844257 | LUAD | Female-baised eQTL |
| rs80324576 | chr6:16212176:C:T | - | 0.060376714111326 | 0.00456854804844257 | LUAD | Female-baised eQTL |
| rs150341740 | chr6:16215101:C:T | - | 0.0603740028381904 | 0.00462757665258972 | LUAD | Female-baised eQTL |
| rs146218333 | chr6:18929034:G:A | - | 0.0633110779361288 | 0.00520156248068871 | LUAD | Female-baised eQTL |
| rs17138843 | chr6:4784195:T:A | - | 0.0582545534043297 | 0.00662808397419206 | LUAD | Female-baised eQTL |
| rs75076424 | chr6:16562560:T:G | - | 0.0584682334512206 | 0.00876229171725301 | LUAD | Female-baised eQTL |
| rs114349054 | chr6:12094696:T:C | - | 0.0516890880758909 | 0.0126885429460902 | LUAD | Female-baised eQTL |
| rs111582969 | chr6:16211008:A:G | - | 0.0527308952138918 | 0.0134942999086197 | LUAD | Female-baised eQTL |
| rs113088754 | chr6:16212691:A:C | - | 0.0527308952138918 | 0.0134942999086197 | LUAD | Female-baised eQTL |
| rs147845031 | chr6:16214996:A:C | - | 0.0526208941714775 | 0.0139004720554253 | LUAD | Female-baised eQTL |
| rs115181853 | chr6:12102267:A:T | - | 0.0544783074884541 | 0.0162643253467074 | LUAD | Female-baised eQTL |
| rs9368392 | chr6:22020673:G:T | - | -0.0407236835615389 | 0.0177472824151103 | LUAD | Female-baised eQTL |
| rs9379142 | chr6:7873445:C:G | - | 0.0533379195754759 | 0.0187035774964501 | LUAD | Female-baised eQTL |
| rs79548802 | chr6:12116092:A:G | - | 0.0520918833935583 | 0.0242480069759542 | LUAD | Female-baised eQTL |
| rs114837894 | chr6:12134294:G:A | - | 0.0556903885075063 | 0.0244199097963985 | LUAD | Female-baised eQTL |
| rs111758821 | chr6:12142354:A:C | - | 0.0556903885075063 | 0.0244199097963985 | LUAD | Female-baised eQTL |
| rs75220612 | chr6:11568420:A:G | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs12199315 | chr6:11569367:C:T | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs10456073 | chr6:11570244:C:T | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs12204093 | chr6:11576700:C:G | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs12192607 | chr6:11578317:G:T | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs12194504 | chr6:11579431:G:T | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs16871482 | chr6:11580963:G:T | - | 0.0523809964416532 | 0.0254595447788964 | LUAD | Female-baised eQTL |
| rs11759478 | chr6:15351477:C:G | - | 0.051375484971463 | 0.0259321961194386 | LUAD | Female-baised eQTL |
| rs9392904 | chr6:7555621:G:C | - | 0.046897772859187 | 0.030833929970205 | LUAD | Female-baised eQTL |
| rs2744146 | chr6:22342418:C:T | - | 0.0444320392713604 | 0.0314607512076759 | LUAD | Female-baised eQTL |
| rs12207526 | chr6:11571512:G:T | - | 0.048854124187521 | 0.0350957403706825 | LUAD | Female-baised eQTL |
| rs17764967 | chr6:11490622:G:C | - | 0.0427924337531834 | 0.0387994349982787 | LUAD | Female-baised eQTL |
| rs12203104 | chr6:11571985:T:G | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs12212790 | chr6:11577233:T:C | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs12211376 | chr6:11577339:A:G | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs12191269 | chr6:11579545:T:G | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs12209963 | chr6:11580044:C:T | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs12196157 | chr6:11580092:G:A | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs16871481 | chr6:11580752:A:G | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs12193579 | chr6:11581362:T:G | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs10947419 | chr6:11581757:A:G | - | 0.0430415508297228 | 0.0394833656161097 | LUAD | Female-baised eQTL |
| rs1042054 | chr6:12164379:C:G | - | 0.049563341444922 | 0.0429609439910362 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs77140603 | chr6:6051781:A:C | - | 0.0802933940314888 | 0.000770554169552255 | LGG | Male-baised eQTL |
| rs1969912 | chr6:6044046:A:G | - | 0.0524628799741918 | 0.00882045206492534 | LGG | Male-baised eQTL |
| rs12182813 | chr6:6045516:G:A | - | 0.0517063881932115 | 0.00931314325050738 | LGG | Male-baised eQTL |
| rs9502396 | chr6:6047016:T:C | - | 0.0517063881932115 | 0.00931314325050738 | LGG | Male-baised eQTL |
| rs9502397 | chr6:6047283:G:A | - | 0.0517063881932115 | 0.00931314325050738 | LGG | Male-baised eQTL |
| rs9504636 | chr6:6049742:A:G | - | 0.0517063881932115 | 0.00931314325050738 | LGG | Male-baised eQTL |
| rs17142071 | chr6:6342144:C:T | - | 0.0825258391846219 | 0.0108269379402551 | LGG | Male-baised eQTL |
| rs9504767 | chr6:6337032:G:C | - | 0.0844115410004238 | 0.0115698970053738 | LGG | Male-baised eQTL |
| rs9504637 | chr6:6049745:A:C | - | 0.0485855005616311 | 0.0189774230489585 | LGG | Male-baised eQTL |
| rs9504638 | chr6:6049756:A:G | - | 0.0485855005616311 | 0.0189774230489585 | LGG | Male-baised eQTL |
| rs75751949 | chr6:8189393:A:G | - | 0.0631708038451676 | 0.0264288336898204 | LGG | Male-baised eQTL |
| rs7768905 | chr6:8184252:G:A | - | 0.0644888042842928 | 0.0387673737139145 | LGG | Male-baised eQTL |
| rs412787 | chr6:13280257:T:C | gene | -0.0569213652593071 | 0.00572955659836433 | KIRC | Male-baised eQTL |
| rs384730 | chr6:13280205:T:A | gene | -0.0561375184924138 | 0.00743802308973399 | KIRC | Male-baised eQTL |
| rs442614 | chr6:13280222:G:A | gene | -0.0561375184924138 | 0.00743802308973399 | KIRC | Male-baised eQTL |
| rs1832023 | chr6:8109882:G:A | - | 0.0548833629250271 | 0.00788357439673246 | KIRC | Male-baised eQTL |
| rs9379166 | chr6:8110933:T:C | - | 0.0544796222710336 | 0.00895000650265568 | KIRC | Male-baised eQTL |
| rs9406090 | chr6:8077649:G:T | - | 0.0550343432732106 | 0.0101637408265544 | KIRC | Male-baised eQTL |
| rs3757098 | chr6:8103593:A:G | - | 0.0542058553356615 | 0.0104400401642302 | KIRC | Male-baised eQTL |
| rs9392962 | chr6:8102257:T:C | - | 0.0552625274737288 | 0.0109089188173832 | KIRC | Male-baised eQTL |
| rs3757096 | chr6:8102815:G:T | - | 0.0547233928661958 | 0.013083733800771 | KIRC | Male-baised eQTL |
| rs1413902 | chr6:8103270:C:T | - | 0.0547233928661958 | 0.013083733800771 | KIRC | Male-baised eQTL |
| rs7768137 | chr6:8101174:C:T | - | 0.0531835995331085 | 0.0137671854967541 | KIRC | Male-baised eQTL |
| rs9379162 | chr6:8077189:C:T | - | 0.0537149454363511 | 0.0145178279041688 | KIRC | Male-baised eQTL |
| rs9502681 | chr6:8089907:G:A | - | 0.0521922313893894 | 0.0171723311433244 | KIRC | Male-baised eQTL |
| rs9406094 | chr6:8107374:G:A | - | 0.0510609910190227 | 0.0203957990829711 | KIRC | Male-baised eQTL |
| rs12209171 | chr6:8092774:A:G | - | 0.0529305274113203 | 0.0205458221508206 | KIRC | Male-baised eQTL |
| rs72496782 | chr6:8100582:G:A | - | 0.0529305274113203 | 0.0205458221508206 | KIRC | Male-baised eQTL |
| rs1316319 | chr6:8105795:T:C | - | 0.0514142285006836 | 0.0211786346407398 | KIRC | Male-baised eQTL |
| rs12197549 | chr6:8085645:C:G | - | 0.0525609103669913 | 0.022267092959872 | KIRC | Male-baised eQTL |
| rs12199241 | chr6:8086267:C:T | - | 0.0525609103669913 | 0.022267092959872 | KIRC | Male-baised eQTL |
| rs1136044 | chr6:8090037:T:G | - | 0.0525609103669913 | 0.022267092959872 | KIRC | Male-baised eQTL |
| rs398151 | chr6:13281396:A:C | gene | -0.0521761630583378 | 0.0234021057965042 | KIRC | Male-baised eQTL |
| rs12215113 | chr6:8104869:C:T | - | 0.0506614853685012 | 0.0247600783633897 | KIRC | Male-baised eQTL |
| rs12195465 | chr6:8075433:A:G | - | 0.0514840579361393 | 0.0248393322848502 | KIRC | Male-baised eQTL |
| rs12196862 | chr6:8075441:T:C | - | 0.0514840579361393 | 0.0248393322848502 | KIRC | Male-baised eQTL |
| rs9378519 | chr6:8071439:A:T | - | 0.0506799000688498 | 0.0256589086673705 | KIRC | Male-baised eQTL |
| rs6909962 | chr6:8076953:T:G | - | 0.0506506383547876 | 0.0278570368110381 | KIRC | Male-baised eQTL |
| rs9392960 | chr6:8095062:T:C | - | 0.0516328885208332 | 0.0285650665198733 | KIRC | Male-baised eQTL |
| rs9392963 | chr6:8108974:C:A | - | 0.0502705940204652 | 0.0318889324417067 | KIRC | Male-baised eQTL |
| rs421057 | chr6:13278696:G:A | gene | -0.0499691448261438 | 0.0328030182153169 | KIRC | Male-baised eQTL |
| rs6923256 | chr6:8109698:T:C | - | 0.0453323976227645 | 0.0378204812879926 | KIRC | Male-baised eQTL |
| rs9328454 | chr6:8082380:C:T | - | 0.0479598114651071 | 0.0404887719357433 | KIRC | Male-baised eQTL |
| rs1932018 | chr6:8109119:T:G | - | 0.04466611383241 | 0.0415586561284717 | KIRC | Male-baised eQTL |
| rs9392961 | chr6:8095396:G:A | - | 0.0492215280769649 | 0.0462855567235307 | KIRC | Male-baised eQTL |
| rs6597299 | chr6:8108774:G:A | - | 0.0431839268589043 | 0.0487194504774146 | KIRC | Male-baised eQTL |
| rs183950792 | chr6:16686961:G:T | - | 0.0434656951313081 | 0.00833124444443029 | BLCA | Male-baised eQTL |
| rs188035817 | chr6:16686963:T:C | - | 0.0434656951313081 | 0.00833124444443029 | BLCA | Male-baised eQTL |
| rs17606174 | chr6:16687314:C:T | - | 0.0434656951313081 | 0.00833124444443029 | BLCA | Male-baised eQTL |
| rs68096947 | chr6:16690089:G:T | - | 0.0440678449619663 | 0.00903335594774264 | BLCA | Male-baised eQTL |
| rs72826614 | chr6:20186386:A:G | - | 0.0586484563958101 | 0.0189665561997039 | BLCA | Male-baised eQTL |
| rs1911 | chr6:11184951:A:G | - | 0.070676716998811 | 0.0410183501300338 | LUAD | Male-baised eQTL |
| rs6456473 | chr6:22221695:C:G | - | -0.0681492858682095 | 0.0134922424626506 | COAD | Male-baised eQTL |
| rs2179551 | chr6:20536507:C:T | - | -0.0790521363541254 | 0.0198347700866319 | COAD | Male-baised eQTL |
| rs7771234 | chr6:9919818:C:A | - | -0.0729283506698773 | 0.033982415901311 | COAD | Male-baised eQTL |
| rs9465800 | chr6:20546657:T:G | - | -0.0722169100442766 | 0.0373952767012889 | COAD | Male-baised eQTL |
| rs9460520 | chr6:20553859:A:G | - | -0.0722169100442766 | 0.0373952767012889 | COAD | Male-baised eQTL |
| rs1474720 | chr6:20575025:T:C | - | -0.0713813947557841 | 0.0418574467141554 | COAD | Male-baised eQTL |
| rs9350255 | chr6:20543805:T:C | - | -0.071060167264992 | 0.0434968290903589 | COAD | Male-baised eQTL |
| rs6918457 | chr6:20566225:G:A | - | -0.071060167264992 | 0.0434968290903589 | COAD | Male-baised eQTL |
| rs2064320 | chr6:20569911:A:G | - | -0.0709112959561598 | 0.0441545841754036 | COAD | Male-baised eQTL |
| rs4712518 | chr6:20608047:G:A | - | -0.0712520759091631 | 0.0446151704517357 | COAD | Male-baised eQTL |
| rs4712517 | chr6:20607984:T:C | - | -0.0703497487852166 | 0.0478904076690506 | COAD | Male-baised eQTL |
| rs1012625 | chr6:20577538:A:G | - | -0.0703005262996179 | 0.0479470961517664 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000145979 |
| CpG Site: cg11807143 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.465754878499186 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg11807143 | chr6:13326073 | gene | -0.465754878499186 | 2.016925690272e-45 | -0.7926011197014996 | 1.47013896709391e-54 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs7754430 | chr6:13763099:T:C | Distant upstream | 0.0417892678667969 | 0.0132394263342053 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs4512225 | chr6:13763556:G:T | Distant upstream | 0.0417892678667969 | 0.0132394263342053 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9382515 | chr6:13767484:C:A | Distant upstream | 0.0402242982736303 | 0.018465215166863 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs7750770 | chr6:13766841:G:A | Distant upstream | 0.0403620635768151 | 0.0190118955567977 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs7775408 | chr6:13766716:T:C | Distant upstream | 0.0400740691376132 | 0.0218967288857399 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6924124 | chr6:13764614:A:G | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs12527304 | chr6:13764771:C:T | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs12523818 | chr6:13764849:G:A | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs12527333 | chr6:13764948:C:T | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs12529434 | chr6:13764966:T:G | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs12527334 | chr6:13765015:C:T | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9367643 | chr6:13765304:A:G | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9382509 | chr6:13765453:T:A | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6907267 | chr6:13765772:G:C | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9382511 | chr6:13766230:C:A | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9382512 | chr6:13766534:A:G | Distant upstream | 0.0397480886207263 | 0.0233226082346741 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6459098 | chr6:13775675:C:T | Distant upstream | 0.0417461491142856 | 0.0265050397182734 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6918597 | chr6:13763915:A:G | Distant upstream | 0.0390973775339161 | 0.0297516758524935 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6923354 | chr6:13764015:T:C | Distant upstream | 0.0390973775339161 | 0.0297516758524935 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6923922 | chr6:13764296:T:C | Distant upstream | 0.0390973775339161 | 0.0297516758524935 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6919448 | chr6:13764327:A:G | Distant upstream | 0.0390973775339161 | 0.0297516758524935 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6939239 | chr6:13764366:G:A | Distant upstream | 0.0390973775339161 | 0.0297516758524935 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9367645 | chr6:13766161:T:G | Distant upstream | 0.037596941450155 | 0.0360624827558143 | KIRC | Female-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs577267 | chr6:13758347:T:G | Distant upstream | -0.0358522340907042 | 0.0438512106984486 | KIRC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6938519 | chr6:12529855:A:G | Distant downstream | -0.0600530386050075 | 0.0359316381524625 | LUAD | Male-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs6925906 | chr6:12359070:G:A | Distant downstream | 0.0405647129418629 | 0.0478627594596968 | LUAD | Male-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs2494770 | chr6:13460654:G:A | Distant upstream | -0.026697747792806 | 0.0406387090176472 | HNSC | Male-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs9394840 | chr6:12413707:T:C | Distant downstream | 0.0240021616316199 | 0.00897446738493326 | LUSC | Male-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs1556386 | chr6:14202816:A:T | Distant upstream | -0.0739623406262362 | 0.00743475435889386 | STAD | Male-baised sQTL |
| exon_skip_456313 | chr6:13325093:13325174 | In-frame | rs73726404 | chr6:14197727:C:T | Distant upstream | -0.0700986873553446 | 0.00753706445615139 | STAD | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TBC1D7 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
