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Gene: ENSG00000145569 |
Summary for FAM105A |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000145569 | Gene symbol | FAM105A |
| Gene name | OTU deubiquitinase with linear linkage specificity like | |
| HGNC | 25629 | |
| Entrez ID | 54491 | |
| Gene type | protein_coding | |
| Synonyms | OTULINL|FLJ11127|NET20 | |
| UniProtAcc | Q9NUU6 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for FAM105A |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FAM105A | 2.04e+03 | -1.22e+00 | 2.28e-01 | -5.36e+00 | 8.19e-08 | 2.83e-07 | LUAD |
| FAM105A | 4.38e+02 | -1.05e+00 | 2.92e-01 | -3.62e+00 | 2.98e-04 | 1.94e-03 | KIRP |
Top |
Sex-biased somatic mutation for FAM105A |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for FAM105A |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg01809941 | chr5:14581295 | CGI:chr5:14581388-14582460 | promoter | 4.25e-01 | 3.25e-01 | 2.96e+00 | 3.05e-03 | 4.16e-03 | 1.00e-01 |
| LIHC | cg04267590 | chr5:14581833 | CGI:chr5:14581388-14582460 | UTR,promoter,exon,gene body | 1.29e-01 | 1.87e-02 | 2.31e+00 | 2.11e-02 | 2.34e-02 | 1.11e-01 |
| LIHC | cg24806126 | chr5:14581511 | CGI:chr5:14581388-14582460 | promoter | 4.51e-01 | 2.98e-01 | 2.97e+00 | 2.98e-03 | 4.17e-03 | 1.52e-01 |
| LIHC | cg18547611 | chr5:14581590 | CGI:chr5:14581388-14582460 | promoter | 2.47e-01 | 8.74e-02 | 2.87e+00 | 4.05e-03 | 5.47e-03 | 1.60e-01 |
| CHOL | cg03600516 | chr5:14581542 | CGI:chr5:14581388-14582460 | promoter | 1.63e-01 | 3.11e-01 | -2.29e+00 | 2.23e-02 | 3.24e-02 | -1.48e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for FAM105A |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for FAM105A |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for FAM105A |
| TFs related to FAM105A. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DLBC | PRDM6 | FAM105A | 1.94e+00 | 2.69e-04 | 3.90e+00 | 9.82e-01 | Female-biased |
| DLBC | ZNF182 | FAM105A | 2.08e+00 | 4.44e-04 | 3.87e+00 | 9.81e-01 | Female-biased |
| DLBC | ZNF225 | FAM105A | 2.17e+00 | 3.89e-04 | 4.00e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF235 | FAM105A | 1.82e+00 | 1.50e-04 | 3.98e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF287 | FAM105A | 1.96e+00 | 2.34e-04 | 3.97e+00 | 9.84e-01 | Female-biased |
| DLBC | ZNF418 | FAM105A | 2.07e+00 | 1.23e-04 | 4.31e+00 | 9.91e-01 | Female-biased |
| DLBC | ZNF487 | FAM105A | 2.00e+00 | 2.33e-04 | 4.01e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF492 | FAM105A | 2.30e+00 | 6.89e-04 | 3.95e+00 | 9.83e-01 | Female-biased |
| DLBC | ZNF613 | FAM105A | 2.24e+00 | 7.14e-04 | 3.87e+00 | 9.81e-01 | Female-biased |
| DLBC | ZNF879 | FAM105A | 2.10e+00 | 2.12e-04 | 4.15e+00 | 9.88e-01 | Female-biased |
| DLBC | ZNF98 | FAM105A | 2.27e+00 | 5.74e-04 | 3.98e+00 | 9.84e-01 | Female-biased |
| READ | FOXB1 | FAM105A | 2.96e+00 | 2.99e-03 | 4.10e+00 | 9.82e-01 | Female-biased |
| READ | ZNF418 | FAM105A | 1.83e+00 | 8.63e-05 | 4.03e+00 | 9.84e-01 | Female-biased |
| SKCM | FOXB1 | FAM105A | 4.23e+00 | 1.21e-02 | 5.15e+00 | 9.82e-01 | Female-biased |
| SKCM | FOXL1 | FAM105A | 3.80e+00 | 8.71e-03 | 4.83e+00 | 9.83e-01 | Female-biased |
| SKCM | NKX6-1 | FAM105A | 3.88e+00 | 9.75e-03 | 4.87e+00 | 9.82e-01 | Female-biased |
| SKCM | ZNF418 | FAM105A | 3.76e+00 | 1.91e-03 | 5.26e+00 | 9.94e-01 | Female-biased |
| FAM105A related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for FAM105A |
| RBPs related to ES in FAM105A. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| FAM105A related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs75838927 | chr5:14716211:C:T | - | 0.179203650348847 | 0.000899787760214013 | STAD | Female-baised eQTL |
| rs116452229 | chr5:14716239:C:A | - | 0.179203650348847 | 0.000899787760214013 | STAD | Female-baised eQTL |
| rs78622564 | chr5:14717686:G:C | - | 0.164484299331634 | 0.00243902139392466 | STAD | Female-baised eQTL |
| rs73046737 | chr5:14616125:T:C | - | 0.139297061900967 | 0.0150241610403972 | STAD | Female-baised eQTL |
| rs116803888 | chr5:14581949:C:G | gene,CDS,exon,promoter | 0.132098859872265 | 0.0216443665169267 | STAD | Female-baised eQTL |
| rs73046720 | chr5:14578327:T:G | - | 0.131833194854826 | 0.0224488007460024 | STAD | Female-baised eQTL |
| rs13152969 | chr5:11110193:T:C | - | 0.107793304511002 | 0.02450062379212 | STAD | Female-baised eQTL |
| rs13170756 | chr5:11110237:C:A | - | 0.107793304511002 | 0.02450062379212 | STAD | Female-baised eQTL |
| rs6886163 | chr5:14697740:A:G | - | 0.12215067506166 | 0.0366286343436057 | STAD | Female-baised eQTL |
| rs60501770 | chr5:14698363:G:T | - | 0.12215067506166 | 0.0366286343436057 | STAD | Female-baised eQTL |
| rs10065032 | chr5:14699926:G:A | - | 0.12215067506166 | 0.0366286343436057 | STAD | Female-baised eQTL |
| rs3045 | chr5:14711166:T:C | - | 0.12215067506166 | 0.0366286343436057 | STAD | Female-baised eQTL |
| rs58936946 | chr5:14711921:A:G | - | 0.12215067506166 | 0.0366286343436057 | STAD | Female-baised eQTL |
| rs17363158 | chr5:14668056:G:A | - | 0.122091931637647 | 0.0367401066932887 | STAD | Female-baised eQTL |
| rs80088960 | chr5:14678359:G:C | - | 0.122091931637647 | 0.0367401066932887 | STAD | Female-baised eQTL |
| rs9885040 | chr5:14658890:C:T | - | 0.122014593950469 | 0.0370498016612246 | STAD | Female-baised eQTL |
| rs10038397 | chr5:14661936:G:A | - | 0.122014593950469 | 0.0370498016612246 | STAD | Female-baised eQTL |
| rs17296475 | chr5:14611855:C:G | gene,exon,UTR | 0.123461512528622 | 0.0373395522204981 | STAD | Female-baised eQTL |
| rs35259796 | chr5:11109762:A:T | - | 0.102132943759168 | 0.0408169721503282 | STAD | Female-baised eQTL |
| rs13155993 | chr5:11108043:C:T | - | 0.101920917621205 | 0.0416582122995508 | STAD | Female-baised eQTL |
| rs7721147 | chr5:8254485:G:T | - | 0.080516323271845 | 0.0497455209479426 | STAD | Female-baised eQTL |
| rs55924288 | chr5:20981167:C:T | - | 0.165885697627326 | 0.000410464031496929 | BLCA | Female-baised eQTL |
| rs74528453 | chr5:20984152:C:A | - | 0.154110698902983 | 0.00098833117300086 | BLCA | Female-baised eQTL |
| rs17238567 | chr5:20964107:G:A | - | 0.147068846210006 | 0.00172944867761578 | BLCA | Female-baised eQTL |
| rs73070114 | chr5:20977525:T:G | - | 0.1470633119512 | 0.00191158485419681 | BLCA | Female-baised eQTL |
| rs10037215 | chr5:20978131:G:A | - | 0.1470633119512 | 0.00191158485419681 | BLCA | Female-baised eQTL |
| rs10045749 | chr5:20978185:A:G | - | 0.1470633119512 | 0.00191158485419681 | BLCA | Female-baised eQTL |
| rs56150014 | chr5:20980344:A:C | - | 0.146649812746727 | 0.00208249597502356 | BLCA | Female-baised eQTL |
| rs55852555 | chr5:20981144:G:A | - | 0.146649812746727 | 0.00208249597502356 | BLCA | Female-baised eQTL |
| rs11951167 | chr5:20982417:A:G | - | 0.146649812746727 | 0.00208249597502356 | BLCA | Female-baised eQTL |
| rs10037400 | chr5:20976659:A:G | - | 0.145884954536714 | 0.00224272704079745 | BLCA | Female-baised eQTL |
| rs73070112 | chr5:20976816:T:C | - | 0.145884954536714 | 0.00224272704079745 | BLCA | Female-baised eQTL |
| rs10473455 | chr5:20972070:A:G | - | 0.147342067800463 | 0.00274658822043594 | BLCA | Female-baised eQTL |
| rs2173589 | chr5:20970703:G:A | - | 0.138963480239852 | 0.00424757264164938 | BLCA | Female-baised eQTL |
| rs28549902 | chr5:20970841:C:A | - | 0.138963480239852 | 0.00424757264164938 | BLCA | Female-baised eQTL |
| rs59877941 | chr5:20965282:C:T | - | 0.138428287309685 | 0.0044899617524805 | BLCA | Female-baised eQTL |
| rs73064163 | chr5:20966552:C:T | - | 0.138428287309685 | 0.0044899617524805 | BLCA | Female-baised eQTL |
| rs73064164 | chr5:20966912:G:A | - | 0.138428287309685 | 0.0044899617524805 | BLCA | Female-baised eQTL |
| rs6859971 | chr5:9725646:C:A | - | 0.163108454007621 | 0.00645762498937991 | BLCA | Female-baised eQTL |
| rs17239680 | chr5:21027887:A:G | - | 0.125790474700831 | 0.010588625686699 | BLCA | Female-baised eQTL |
| rs390181 | chr5:21083802:G:T | - | 0.125790474700831 | 0.010588625686699 | BLCA | Female-baised eQTL |
| rs62337717 | chr5:4883158:G:A | - | 0.0541650191554667 | 0.000758242030249606 | LUAD | Female-baised eQTL |
| rs7722501 | chr5:21764787:G:A | - | 0.0509182653588998 | 0.000860403466403816 | LUAD | Female-baised eQTL |
| rs80302401 | chr5:6136697:C:T | - | 0.0515724150226111 | 0.00204784648139703 | LUAD | Female-baised eQTL |
| rs4391167 | chr5:19087674:A:G | - | 0.0465434899710809 | 0.00333973357528131 | LUAD | Female-baised eQTL |
| rs12189140 | chr5:6851100:C:T | - | 0.0485601513864574 | 0.003749839802177 | LUAD | Female-baised eQTL |
| rs728452 | chr5:4807912:T:G | - | 0.0436873813505471 | 0.00430328238975773 | LUAD | Female-baised eQTL |
| rs12054808 | chr5:19085872:G:A | - | 0.045832737763938 | 0.00432239632638897 | LUAD | Female-baised eQTL |
| rs3913374 | chr5:4884896:C:T | - | 0.0467261238224643 | 0.00443859843288774 | LUAD | Female-baised eQTL |
| rs71597582 | chr5:9384709:T:C | - | 0.0460505543665392 | 0.00464266735513632 | LUAD | Female-baised eQTL |
| rs2526125 | chr5:9384713:T:C | - | 0.0460505543665392 | 0.00464266735513632 | LUAD | Female-baised eQTL |
| rs57261486 | chr5:21759775:C:A | - | 0.0441135305638602 | 0.00473257171221084 | LUAD | Female-baised eQTL |
| rs1173215 | chr5:4825685:T:C | - | 0.0426366966963742 | 0.00552002834273443 | LUAD | Female-baised eQTL |
| rs190429072 | chr5:22155443:A:T | - | 0.041738244328936 | 0.00926900249078855 | LUAD | Female-baised eQTL |
| rs2937518 | chr5:18754346:G:C | - | 0.0366095179108076 | 0.0106027319019051 | LUAD | Female-baised eQTL |
| rs7700562 | chr5:14539377:G:A | - | 0.0325984410304848 | 0.0113138660705091 | LUAD | Female-baised eQTL |
| rs12055070 | chr5:14540576:C:T | - | 0.0322907814415121 | 0.0121756178910917 | LUAD | Female-baised eQTL |
| rs6881132 | chr5:14547016:T:C | - | 0.0322869576913306 | 0.01227142504687 | LUAD | Female-baised eQTL |
| rs3911958 | chr5:14544711:T:C | - | 0.0320782675271011 | 0.0125317624735052 | LUAD | Female-baised eQTL |
| rs3866213 | chr5:14544775:C:T | - | 0.0320782675271011 | 0.0125317624735052 | LUAD | Female-baised eQTL |
| rs7448492 | chr5:14545723:A:G | - | 0.0320782675271011 | 0.0125317624735052 | LUAD | Female-baised eQTL |
| rs13163800 | chr5:14541436:G:A | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs13163912 | chr5:14541453:G:A | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs12514881 | chr5:14541635:A:G | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs10077816 | chr5:14542040:T:C | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs34595880 | chr5:14542734:C:T | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs7722299 | chr5:14543721:G:A | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs7722451 | chr5:14543808:G:C | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs10074133 | chr5:14543868:C:T | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs10060805 | chr5:14544194:A:T | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs4141697 | chr5:14544313:T:C | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs4141696 | chr5:14544508:C:T | - | 0.0320480845742639 | 0.0127683387662972 | LUAD | Female-baised eQTL |
| rs2401903 | chr5:14545854:C:T | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs2401904 | chr5:14545970:A:G | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs2401905 | chr5:14545995:T:C | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs10079996 | chr5:14546193:C:T | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs66866482 | chr5:14546348:C:A | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs6880407 | chr5:14546587:T:C | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs6858903 | chr5:14546698:A:T | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs6859539 | chr5:14546811:G:A | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs11133790 | chr5:14546967:T:C | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs11740449 | chr5:14547415:A:G | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs11133791 | chr5:14547515:C:T | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs10474698 | chr5:14547520:G:A | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs10474699 | chr5:14547565:C:G | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs10474700 | chr5:14547907:G:A | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs11747299 | chr5:14548150:G:A | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs11747884 | chr5:14548155:C:T | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs4702040 | chr5:14548292:A:G | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs4701611 | chr5:14548712:T:C | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs66799950 | chr5:14548992:A:T | - | 0.0321563203774799 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs2937517 | chr5:18751399:G:C | - | 0.0362399531957389 | 0.0133713421404479 | LUAD | Female-baised eQTL |
| rs2102147 | chr5:18750131:G:A | - | 0.0352432340335852 | 0.0145870155551701 | LUAD | Female-baised eQTL |
| rs11133789 | chr5:14540287:A:G | - | 0.0318242046926615 | 0.0146801133696286 | LUAD | Female-baised eQTL |
| rs3993996 | chr5:14545789:C:T | - | 0.0311704060273569 | 0.0163795370142875 | LUAD | Female-baised eQTL |
| rs78135265 | chr5:8875022:C:G | - | 0.032861641165445 | 0.0172036370494001 | LUAD | Female-baised eQTL |
| rs78873547 | chr5:9856749:A:C | - | 0.0405958938623538 | 0.0173983795295165 | LUAD | Female-baised eQTL |
| rs17304135 | chr5:8874912:A:G | - | 0.0327983586712025 | 0.0177011892138964 | LUAD | Female-baised eQTL |
| rs67206926 | chr5:14548357:C:T | - | 0.030427966769401 | 0.0199355036170821 | LUAD | Female-baised eQTL |
| rs2082007 | chr5:14548857:C:T | - | 0.0302269388662878 | 0.0207633623432489 | LUAD | Female-baised eQTL |
| rs2962213 | chr5:18749989:A:G | - | 0.0343124597799563 | 0.0208423517150104 | LUAD | Female-baised eQTL |
| rs2962215 | chr5:18750144:G:A | - | 0.0343124597799563 | 0.0208423517150104 | LUAD | Female-baised eQTL |
| rs55949239 | chr5:4881301:C:G | - | 0.0357050898914422 | 0.0231974406986736 | LUAD | Female-baised eQTL |
| rs56127936 | chr5:4882189:C:T | - | 0.0357050898914422 | 0.0231974406986736 | LUAD | Female-baised eQTL |
| rs2962212 | chr5:18746725:T:C | - | 0.0327151998634496 | 0.0240413840539837 | LUAD | Female-baised eQTL |
| rs6452064 | chr5:22162618:A:G | - | -0.0335896837808572 | 0.0297652150341136 | LUAD | Female-baised eQTL |
| rs17752940 | chr5:4886494:A:G | - | 0.0348446342263132 | 0.032969876429108 | LUAD | Female-baised eQTL |
| rs16877578 | chr5:6572245:G:A | - | 0.0370618523591051 | 0.0372477842071186 | LUAD | Female-baised eQTL |
| rs2962220 | chr5:18756585:G:A | - | 0.03110057681449 | 0.0392377108720353 | LUAD | Female-baised eQTL |
| rs4582273 | chr5:14545898:A:G | - | 0.0265258046866079 | 0.0393610753918895 | LUAD | Female-baised eQTL |
| rs58454749 | chr5:10156474:G:A | - | 0.0341076181274463 | 0.0411210579983493 | LUAD | Female-baised eQTL |
| rs12653595 | chr5:19099573:T:C | - | 0.0319573842466591 | 0.0427473910195855 | LUAD | Female-baised eQTL |
| rs72745539 | chr5:19101924:C:A | - | 0.0319181277158441 | 0.0434339512231758 | LUAD | Female-baised eQTL |
| rs16883661 | chr5:9837974:A:G | - | 0.0349401830225543 | 0.0441739069663764 | LUAD | Female-baised eQTL |
| rs16878072 | chr5:6850502:G:A | - | 0.0362323986227892 | 0.0442244930246143 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12655266 | chr5:19923682:A:G | - | -0.105612084491437 | 0.00231926436524421 | HNSC | Male-baised eQTL |
| rs7726481 | chr5:6832973:C:A | - | 0.109315009653607 | 0.0355980890660951 | STAD | Male-baised eQTL |
| rs10061520 | chr5:12099977:T:C | - | 0.0806198870954763 | 0.00184046360384315 | KIRC | Male-baised eQTL |
| rs7379155 | chr5:22166823:A:G | - | -0.0621170915021644 | 0.0310069093481895 | KIRC | Male-baised eQTL |
| rs75413814 | chr5:8044845:G:C | - | -0.0434454910967105 | 0.0236113163295764 | BLCA | Male-baised eQTL |
| rs13176871 | chr5:8036742:C:T | - | -0.0431523973560729 | 0.0264064495875424 | BLCA | Male-baised eQTL |
| rs1006152 | chr5:7150919:G:A | - | 0.0480767328179301 | 0.0417750729028868 | BLCA | Male-baised eQTL |
| rs2962172 | chr5:18284849:G:A | - | 0.0961528116989426 | 0.00155695097003851 | LUAD | Male-baised eQTL |
| rs314020 | chr5:18283968:C:A | - | 0.095554984178986 | 0.00173218572569297 | LUAD | Male-baised eQTL |
| rs35029754 | chr5:5561976:G:A | - | 0.15565387513234 | 0.0107996150288408 | LUAD | Male-baised eQTL |
| rs35694069 | chr5:5562698:G:T | - | 0.15565387513234 | 0.0107996150288408 | LUAD | Male-baised eQTL |
| rs34153128 | chr5:5563584:G:C | - | 0.15565387513234 | 0.0107996150288408 | LUAD | Male-baised eQTL |
| rs13181500 | chr5:5561177:T:C | - | 0.149179528299021 | 0.0111053312003904 | LUAD | Male-baised eQTL |
| rs2102063 | chr5:18312757:C:A | - | 0.0800403193769084 | 0.0153723923486071 | LUAD | Male-baised eQTL |
| rs1697112 | chr5:18290261:A:G | - | 0.0851871350802479 | 0.0188729510230435 | LUAD | Male-baised eQTL |
| rs17788422 | chr5:5567477:G:A | - | 0.145450785733759 | 0.0208697009851733 | LUAD | Male-baised eQTL |
| rs12516489 | chr5:18274750:G:A | - | 0.0814020818189162 | 0.0267256789642644 | LUAD | Male-baised eQTL |
| rs314019 | chr5:18281918:A:G | - | 0.0803992713332994 | 0.0294735369054391 | LUAD | Male-baised eQTL |
| rs1393264 | chr5:15956884:C:G | - | 0.116517019049183 | 0.0210574559286 | COAD | Male-baised eQTL |
| rs484418 | chr5:6608764:A:G | - | -0.0611692040240232 | 0.0346775629260011 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000145569 |
| CpG Site: cg26330063 | |
| Position to Gene: gene,exon | |
| Male Effect: -0.210298649662469 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg26330063 | chr5:14614626 | gene,exon | -0.210298649662469 | 1.15511854605058e-05 | -0.3595380945964808 | 3.2999540869841754e-08 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of FAM105A |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
