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Gene: ENSG00000145349 |
Summary for CAMK2D |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000145349 | Gene symbol | CAMK2D |
| Gene name | calcium/calmodulin dependent protein kinase II delta | |
| HGNC | 1462 | |
| Entrez ID | 817 | |
| Gene type | protein_coding | |
| Synonyms | CAMK2D| | |
| UniProtAcc | Q13557 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000145349 | CAMK2D | DB07853 | 2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile | SmallMoleculeDrug |
| ENSG00000145349 | CAMK2D | DB08039 | (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE | SmallMoleculeDrug |
| ENSG00000145349 | CAMK2D | DB12010 | Fostamatinib | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for CAMK2D |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CAMK2D | 1.79e+03 | -1.08e+00 | 2.67e-01 | -4.02e+00 | 5.73e-05 | 2.73e-04 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CAMK2D | 1.65e+03 | -1.28e+00 | 2.39e-01 | -5.37e+00 | 8.00e-08 | 9.52e-07 | READ |
Top |
Sex-biased somatic mutation for CAMK2D |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for CAMK2D |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg13975660 | chr4:113760684 | CGI:chr4:113760913-113761730 | promoter,gene body | 2.38e-01 | 9.69e-02 | 2.17e+00 | 2.99e-02 | 3.11e-02 | 1.41e-01 |
Top |
Exon skipping events with PSI in TCGA for CAMK2D |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| COAD | exon_skip_431914 | 4.02e-02 | 1.44e-01 | -4.24e+00 | 2.27e-05 | 1.79e-04 | -1.04e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| READ | exon_skip_431914 | 4.33e-02 | 2.56e-01 | -3.29e+00 | 1.01e-03 | 7.09e-03 | -2.12e-01 |
Top |
RNA A-to-I editing events in TCGA for CAMK2D |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for CAMK2D |
| TFs related to CAMK2D. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | ALX1 | CAMK2D | 3.94e+00 | 1.26e-02 | 4.74e+00 | 9.82e-01 | Female-biased |
| BLCA | ALX3 | CAMK2D | 4.34e+00 | 1.46e-02 | 5.11e+00 | 9.83e-01 | Female-biased |
| BLCA | FOXA3 | CAMK2D | 3.52e+00 | 8.26e-03 | 4.42e+00 | 9.83e-01 | Female-biased |
| BLCA | HESX1 | CAMK2D | 3.94e+00 | 1.28e-02 | 4.73e+00 | 9.82e-01 | Female-biased |
| BLCA | HOXA9 | CAMK2D | 4.02e+00 | 1.22e-02 | 4.83e+00 | 9.83e-01 | Female-biased |
| BLCA | PRRX1 | CAMK2D | 4.02e+00 | 1.04e-02 | 4.86e+00 | 9.85e-01 | Female-biased |
| BLCA | UNCX | CAMK2D | 3.91e+00 | 1.13e-02 | 4.73e+00 | 9.83e-01 | Female-biased |
| DLBC | ZNF418 | CAMK2D | 4.26e+00 | 9.89e-01 | 2.54e+00 | 4.32e-04 | Male-biased |
| LAML | ALX1 | CAMK2D | 3.01e+00 | 2.54e-03 | 4.25e+00 | 9.85e-01 | Female-biased |
| LAML | ALX3 | CAMK2D | 3.70e+00 | 5.75e-03 | 4.75e+00 | 9.88e-01 | Female-biased |
| LAML | HESX1 | CAMK2D | 3.25e+00 | 4.90e-03 | 4.32e+00 | 9.84e-01 | Female-biased |
| LAML | HMBOX1 | CAMK2D | 4.87e+00 | 1.67e-02 | 5.63e+00 | 9.82e-01 | Female-biased |
| LAML | HOXA9 | CAMK2D | 3.24e+00 | 5.05e-03 | 4.31e+00 | 9.84e-01 | Female-biased |
| LAML | MEF2B | CAMK2D | 3.69e+00 | 1.17e-02 | 4.54e+00 | 9.80e-01 | Female-biased |
| LAML | PRRX1 | CAMK2D | 3.33e+00 | 4.26e-03 | 4.45e+00 | 9.86e-01 | Female-biased |
| LAML | SOX14 | CAMK2D | 3.14e+00 | 5.54e-03 | 4.19e+00 | 9.81e-01 | Female-biased |
| LAML | SOX15 | CAMK2D | 2.96e+00 | 3.95e-03 | 4.09e+00 | 9.80e-01 | Female-biased |
| LAML | UNCX | CAMK2D | 3.02e+00 | 3.60e-03 | 4.17e+00 | 9.82e-01 | Female-biased |
| LAML | ZNF211 | CAMK2D | 4.38e+00 | 1.15e-02 | 5.25e+00 | 9.86e-01 | Female-biased |
| UVM | ZNF418 | CAMK2D | 5.17e+00 | 9.83e-01 | 3.88e+00 | 1.06e-02 | Male-biased |
| CAMK2D related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for CAMK2D |
| RBPs related to ES in CAMK2D. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KIRP | SRSF2 | exon_skip_431917 | 8.80e+00 | 7.18e-03 | 9.16e+00 | 9.89e-01 | Female-biased |
| READ | SRSF2 | exon_skip_431917 | 9.13e+00 | 9.90e-01 | 8.76e+00 | 6.62e-03 | Male-biased |
| THCA | SRSF2 | exon_skip_431917 | 9.14e+00 | 9.93e-01 | 8.76e+00 | 2.88e-03 | Male-biased |
| CAMK2D related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs78119990 | chr4:111315913:T:G | - | 0.147300959429749 | 0.0221836377648061 | BLCA | Female-baised eQTL |
| rs4698775 | chr4:109669323:G:T | - | -0.0553813152088178 | 0.00462369108490607 | LUAD | Female-baised eQTL |
| rs6824542 | chr4:109675124:C:A | - | 0.0525142117009607 | 0.00969345533289632 | LUAD | Female-baised eQTL |
| rs1448798 | chr4:110702029:A:G | - | 0.0495716684473255 | 0.0108883477388673 | LUAD | Female-baised eQTL |
| rs6533446 | chr4:109656726:A:G | - | 0.0516554033825984 | 0.0115159333345089 | LUAD | Female-baised eQTL |
| rs62327660 | chr4:109647274:G:A | - | 0.0508944144562441 | 0.0136070517236124 | LUAD | Female-baised eQTL |
| rs6858416 | chr4:109649835:A:G | - | 0.0508944144562441 | 0.0136070517236124 | LUAD | Female-baised eQTL |
| rs6824270 | chr4:109652183:C:T | - | 0.0508944144562441 | 0.0136070517236124 | LUAD | Female-baised eQTL |
| rs2158204 | chr4:109658379:A:C | - | -0.0489959724542588 | 0.0165926899655667 | LUAD | Female-baised eQTL |
| rs1543812 | chr4:109658928:G:T | - | -0.0489959724542588 | 0.0165926899655667 | LUAD | Female-baised eQTL |
| rs13128388 | chr4:109647000:T:C | - | -0.0490487676748902 | 0.0173380264372511 | LUAD | Female-baised eQTL |
| rs16997169 | chr4:110707925:C:T | - | 0.0489652182124783 | 0.0179995205028832 | LUAD | Female-baised eQTL |
| rs10033935 | chr4:122803102:G:A | - | 0.0874089169914415 | 0.0249677384075093 | LUAD | Female-baised eQTL |
| rs9998081 | chr4:122804294:A:G | - | 0.0874089169914415 | 0.0249677384075093 | LUAD | Female-baised eQTL |
| rs9990935 | chr4:122805491:T:C | - | 0.0869924422403677 | 0.0262603956883403 | LUAD | Female-baised eQTL |
| rs10005572 | chr4:122801479:A:G | - | 0.0861847695290558 | 0.0290605867424891 | LUAD | Female-baised eQTL |
| rs7690921 | chr4:109657590:T:A | - | -0.0461355931909762 | 0.0291207633408252 | LUAD | Female-baised eQTL |
| rs11734973 | chr4:109626758:A:C | - | 0.0492067717648709 | 0.0311884335545641 | LUAD | Female-baised eQTL |
| rs2346835 | chr4:109641087:A:G | - | -0.0471321877698883 | 0.0318730893091598 | LUAD | Female-baised eQTL |
| rs7658262 | chr4:109655818:C:G | - | 0.0473538670768545 | 0.0366045221413466 | LUAD | Female-baised eQTL |
| rs72674829 | chr4:109642939:G:A | - | 0.0468492718659276 | 0.0381996635420148 | LUAD | Female-baised eQTL |
| rs4527540 | chr4:110707982:T:C | - | 0.0448108083991516 | 0.0443924705868375 | LUAD | Female-baised eQTL |
| rs62326058 | chr4:109636260:C:A | - | 0.0463260154082638 | 0.0447083610153366 | LUAD | Female-baised eQTL |
| rs10031371 | chr4:122802608:G:A | - | 0.0807599578668076 | 0.0460966851874444 | LUAD | Female-baised eQTL |
| rs62326057 | chr4:109628294:A:G | - | 0.0471275579639297 | 0.0478267413283079 | LUAD | Female-baised eQTL |
| rs1026156 | chr4:122772858:T:C | - | -0.0801548682258762 | 0.0491189963095023 | LUAD | Female-baised eQTL |
| rs17006127 | chr4:122770970:A:G | - | 0.0801548682258762 | 0.0491189963095023 | LUAD | Female-baised eQTL |
| rs1116224 | chr4:122793076:A:G | - | 0.0801548682258762 | 0.0491189963095023 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs9307373 | chr4:111676761:C:G | - | 0.0971935901694342 | 1.7918025377275e-06 | KIRC | Male-baised eQTL |
| rs67495319 | chr4:115599330:T:A | - | 0.0836524903462721 | 0.00165080741790124 | KIRC | Male-baised eQTL |
| rs67718438 | chr4:115600758:A:T | - | 0.0836524903462721 | 0.00165080741790124 | KIRC | Male-baised eQTL |
| rs72676138 | chr4:115599484:A:G | - | 0.0819870338231561 | 0.00187076350299257 | KIRC | Male-baised eQTL |
| rs72676130 | chr4:115590557:T:C | - | 0.0807865082970849 | 0.00365194765528333 | KIRC | Male-baised eQTL |
| rs72676133 | chr4:115591761:A:G | - | 0.0807865082970849 | 0.00365194765528333 | KIRC | Male-baised eQTL |
| rs12512423 | chr4:110598463:T:C | - | 0.0531996157003638 | 0.00559185769476133 | KIRC | Male-baised eQTL |
| rs17048021 | chr4:115608770:C:T | - | 0.0713722533209203 | 0.00609667996613191 | KIRC | Male-baised eQTL |
| rs59561207 | chr4:121685071:T:C | - | 0.0681444744885003 | 0.00646040458097287 | KIRC | Male-baised eQTL |
| rs62319820 | chr4:121697217:G:A | - | 0.0708325756053252 | 0.00840529131707232 | KIRC | Male-baised eQTL |
| rs9995591 | chr4:121694605:G:A | - | 0.0695089945388761 | 0.00847635355366137 | KIRC | Male-baised eQTL |
| rs62319818 | chr4:121689341:C:T | - | 0.0685398627029401 | 0.00964249341840739 | KIRC | Male-baised eQTL |
| rs1448809 | chr4:110594718:C:T | - | 0.0484912010936471 | 0.0103207950072132 | KIRC | Male-baised eQTL |
| rs6840832 | chr4:115677855:G:A | - | 0.072081821294172 | 0.0156639420721319 | KIRC | Male-baised eQTL |
| rs112597960 | chr4:115682988:C:T | - | 0.072081821294172 | 0.0156639420721319 | KIRC | Male-baised eQTL |
| rs76996764 | chr4:110611624:G:T | - | 0.0489426753543005 | 0.0178617188761862 | KIRC | Male-baised eQTL |
| rs76310795 | chr4:121268729:G:A | - | 0.0637001762464716 | 0.0188783967949624 | KIRC | Male-baised eQTL |
| rs79389743 | chr4:118944601:G:A | - | 0.0438596491223368 | 0.020856670480299 | KIRC | Male-baised eQTL |
| rs75490158 | chr4:110611474:C:G | - | 0.0476651962120395 | 0.0243948713413864 | KIRC | Male-baised eQTL |
| rs10050264 | chr4:115671250:A:G | - | 0.0640804283627612 | 0.0264047982127024 | KIRC | Male-baised eQTL |
| rs7660246 | chr4:110611909:G:A | - | 0.0456496060819686 | 0.0386370434581404 | KIRC | Male-baised eQTL |
| rs7688577 | chr4:110264037:T:C | - | 0.0591605242429222 | 0.0419093172937866 | BLCA | Male-baised eQTL |
| rs6847521 | chr4:110264611:T:C | - | 0.0591605242429222 | 0.0419093172937866 | BLCA | Male-baised eQTL |
| rs13107009 | chr4:110262328:C:T | - | 0.0587686195054124 | 0.047268453862392 | BLCA | Male-baised eQTL |
| rs13109022 | chr4:110263775:T:C | - | 0.0587686195054124 | 0.047268453862392 | BLCA | Male-baised eQTL |
| rs17041821 | chr4:110471807:C:T | - | 0.138744112186452 | 0.000154024827570073 | LUAD | Male-baised eQTL |
| rs203723 | chr4:107397536:C:T | - | -0.0967250959249974 | 0.00811614515398395 | LUAD | Male-baised eQTL |
| rs28657379 | chr4:117016794:T:C | - | 0.131589894059732 | 0.04241584205147 | LUAD | Male-baised eQTL |
| rs17048079 | chr4:115768351:T:G | - | 0.151963961711131 | 0.000170056288192357 | COAD | Male-baised eQTL |
| rs147954254 | chr4:105412823:T:C | - | 0.217012511483402 | 0.000440705633325072 | COAD | Male-baised eQTL |
| rs17257590 | chr4:105404697:T:A | - | 0.215236199783329 | 0.000521817389791764 | COAD | Male-baised eQTL |
| rs141867660 | chr4:105412926:G:A | - | 0.215236199783329 | 0.000521817389791764 | COAD | Male-baised eQTL |
| rs6854580 | chr4:115767828:C:A | - | 0.137283872772821 | 0.00092815060920801 | COAD | Male-baised eQTL |
| rs72679065 | chr4:115769456:C:G | - | 0.137633106029515 | 0.00181060795437367 | COAD | Male-baised eQTL |
| rs62315057 | chr4:113622567:C:A | gene | 0.156804538465971 | 0.00264509173722199 | COAD | Male-baised eQTL |
| rs11098394 | chr4:117374522:T:A | - | 0.0951943894821556 | 0.00389764725072154 | COAD | Male-baised eQTL |
| rs11729280 | chr4:117353404:A:G | - | -0.0945035716090663 | 0.00457184537283629 | COAD | Male-baised eQTL |
| rs1476545 | chr4:109610643:T:A | - | -0.0872604156436587 | 0.0123935746407264 | COAD | Male-baised eQTL |
| rs13136336 | chr4:120606039:A:G | - | 0.136867426195288 | 0.013220747877042 | COAD | Male-baised eQTL |
| rs72674276 | chr4:115510113:C:T | - | 0.137796037541474 | 0.01483137501495 | COAD | Male-baised eQTL |
| rs6534033 | chr4:117404900:G:T | - | -0.0785241816461218 | 0.0160814025285167 | COAD | Male-baised eQTL |
| rs62317380 | chr4:115509498:T:C | - | 0.139558993618004 | 0.0166706674427442 | COAD | Male-baised eQTL |
| rs6815377 | chr4:109625960:C:G | - | -0.0839372194630242 | 0.0168655825852743 | COAD | Male-baised eQTL |
| rs11098472 | chr4:119034921:G:C | - | 0.0819630353864024 | 0.019093179897907 | COAD | Male-baised eQTL |
| rs1490612 | chr4:105489698:G:T | - | 0.160402270135304 | 0.0192907799960404 | COAD | Male-baised eQTL |
| rs7678410 | chr4:115529078:C:T | - | 0.131333190035515 | 0.0195704646299114 | COAD | Male-baised eQTL |
| rs80041647 | chr4:118959312:G:T | - | 0.120889790062744 | 0.0205018908504462 | COAD | Male-baised eQTL |
| rs2635240 | chr4:117528197:C:G | - | -0.0751480587907919 | 0.0214384913607699 | COAD | Male-baised eQTL |
| rs79970578 | chr4:116348706:A:T | - | -0.102459686115371 | 0.0217859842697226 | COAD | Male-baised eQTL |
| rs62317384 | chr4:115521054:C:A | - | 0.133929249620985 | 0.023526400871783 | COAD | Male-baised eQTL |
| rs996890 | chr4:115769706:T:C | - | 0.102734062664802 | 0.0240701178649109 | COAD | Male-baised eQTL |
| rs11723566 | chr4:121648885:C:A | - | 0.0783043571529643 | 0.024837445425892 | COAD | Male-baised eQTL |
| rs197221 | chr4:109598607:G:C | - | -0.0804567828816822 | 0.0260872911991213 | COAD | Male-baised eQTL |
| rs148853476 | chr4:117519380:T:C | - | 0.0729328596979901 | 0.0275064829418267 | COAD | Male-baised eQTL |
| rs11562897 | chr4:117508253:T:G | - | 0.0722605065071915 | 0.0292777287125092 | COAD | Male-baised eQTL |
| rs62317382 | chr4:115514974:A:C | - | 0.126116765352645 | 0.0297465159255925 | COAD | Male-baised eQTL |
| rs114744099 | chr4:115510584:A:T | - | 0.12815165316234 | 0.0298603060120843 | COAD | Male-baised eQTL |
| rs71608349 | chr4:118189857:T:C | - | 0.122893590736052 | 0.0306785818340826 | COAD | Male-baised eQTL |
| rs6533209 | chr4:105561730:A:G | - | -0.07418123463602 | 0.0318996785529213 | COAD | Male-baised eQTL |
| rs7667819 | chr4:113581404:G:T | gene | -0.085161246427111 | 0.0329227176844833 | COAD | Male-baised eQTL |
| rs728061 | chr4:113581573:C:G | gene | -0.085161246427111 | 0.0329227176844833 | COAD | Male-baised eQTL |
| rs728060 | chr4:113581665:C:T | gene | -0.085161246427111 | 0.0329227176844833 | COAD | Male-baised eQTL |
| rs1978130 | chr4:113575945:C:T | gene | -0.0849635421194092 | 0.0340479142321947 | COAD | Male-baised eQTL |
| rs2068108 | chr4:113577540:G:A | gene | -0.0849635421194092 | 0.0340479142321947 | COAD | Male-baised eQTL |
| rs4286610 | chr4:117373044:G:A | - | -0.0774743241381265 | 0.0347824118735707 | COAD | Male-baised eQTL |
| rs197231 | chr4:109593791:A:T | - | -0.0784604848930617 | 0.035087131929022 | COAD | Male-baised eQTL |
| rs10488894 | chr4:113583162:G:C | gene | -0.0796458438732262 | 0.0352691468984315 | COAD | Male-baised eQTL |
| rs6848104 | chr4:113093668:C:T | - | -0.0932041690871928 | 0.0354685242455259 | COAD | Male-baised eQTL |
| rs2635334 | chr4:117505165:C:A | - | -0.0715469538278767 | 0.0359221277348731 | COAD | Male-baised eQTL |
| rs55787490 | chr4:115508007:G:A | - | 0.127499180626419 | 0.0362295869804158 | COAD | Male-baised eQTL |
| rs17861774 | chr4:117349493:G:C | - | 0.0774156759975475 | 0.0366548162337057 | COAD | Male-baised eQTL |
| rs9992793 | chr4:105404743:C:T | - | 0.0743512031872662 | 0.0375801702177867 | COAD | Male-baised eQTL |
| rs2635190 | chr4:117512484:C:T | - | -0.0725599150205066 | 0.0376558429533112 | COAD | Male-baised eQTL |
| rs17861773 | chr4:117348028:C:T | - | 0.0750939295683358 | 0.0378987682577091 | COAD | Male-baised eQTL |
| rs62317969 | chr4:115556570:C:G | - | 0.129626059881912 | 0.0380461616039749 | COAD | Male-baised eQTL |
| rs6851826 | chr4:113578074:C:T | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs11731920 | chr4:113578261:G:A | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs11731896 | chr4:113578411:C:G | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs13121973 | chr4:113578745:C:T | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs10461193 | chr4:113579144:C:A | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs1978132 | chr4:113579750:A:G | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs28456003 | chr4:113580701:T:C | gene | -0.0835870189722908 | 0.0385557460528723 | COAD | Male-baised eQTL |
| rs75979367 | chr4:118112482:C:T | - | 0.119716064628416 | 0.0387166366112324 | COAD | Male-baised eQTL |
| rs62317965 | chr4:115545541:C:T | - | 0.124299143125514 | 0.0392927514818874 | COAD | Male-baised eQTL |
| rs2635218 | chr4:117517355:A:T | - | -0.0717850756811191 | 0.0402013518119895 | COAD | Male-baised eQTL |
| rs10461150 | chr4:113579397:G:A | gene | -0.0832353686478616 | 0.0404657445246514 | COAD | Male-baised eQTL |
| rs62317962 | chr4:115537995:C:G | - | 0.127251709472593 | 0.0416507296206163 | COAD | Male-baised eQTL |
| rs71608355 | chr4:118230345:G:A | - | 0.11865954155184 | 0.0418482736993044 | COAD | Male-baised eQTL |
| rs13130953 | chr4:118231999:T:C | - | 0.11865954155184 | 0.0418482736993044 | COAD | Male-baised eQTL |
| rs2969625 | chr4:117510252:A:G | - | -0.0709275510243412 | 0.0421366455027063 | COAD | Male-baised eQTL |
| rs6533700 | chr4:113577873:C:T | gene | -0.0829827543235762 | 0.0425009152889592 | COAD | Male-baised eQTL |
| rs62317963 | chr4:115540333:C:T | - | 0.126882748854996 | 0.0425812266117594 | COAD | Male-baised eQTL |
| rs62317968 | chr4:115550207:G:A | - | 0.126882748854996 | 0.0425812266117594 | COAD | Male-baised eQTL |
| rs13126087 | chr4:120051784:A:G | - | 0.0775173919358504 | 0.0434779632778143 | COAD | Male-baised eQTL |
| rs2635239 | chr4:117527511:T:G | - | -0.0719846834062011 | 0.0441612664723385 | COAD | Male-baised eQTL |
| rs2635329 | chr4:117522752:T:C | - | -0.0712145419035034 | 0.0443083908315198 | COAD | Male-baised eQTL |
| rs2635331 | chr4:117525639:A:G | - | -0.0712145419035034 | 0.0443083908315198 | COAD | Male-baised eQTL |
| rs71608356 | chr4:118237486:A:T | - | 0.117520089171916 | 0.0455629142495068 | COAD | Male-baised eQTL |
| rs17594257 | chr4:118239320:T:C | - | 0.117520089171916 | 0.0455629142495068 | COAD | Male-baised eQTL |
| rs13125461 | chr4:118254664:T:A | - | 0.117520089171916 | 0.0455629142495068 | COAD | Male-baised eQTL |
| rs2635341 | chr4:117545155:C:T | - | -0.0690098893062434 | 0.0457011183837328 | COAD | Male-baised eQTL |
| rs2969622 | chr4:117552276:C:G | - | -0.0711784954666013 | 0.0458341892092875 | COAD | Male-baised eQTL |
| rs1984616 | chr4:117546614:G:T | - | -0.0687239916627167 | 0.0461070306888686 | COAD | Male-baised eQTL |
| rs2635342 | chr4:117547353:G:A | - | -0.0687239916627167 | 0.0461070306888686 | COAD | Male-baised eQTL |
| rs2130237 | chr4:117547961:C:T | - | -0.0687239916627167 | 0.0461070306888686 | COAD | Male-baised eQTL |
| rs2247228 | chr4:117548018:G:A | - | -0.0687239916627167 | 0.0461070306888686 | COAD | Male-baised eQTL |
| rs1352574 | chr4:117515828:A:G | - | -0.0713553484828481 | 0.0461828384104675 | COAD | Male-baised eQTL |
| rs1906859 | chr4:117518049:C:G | - | -0.0713553484828481 | 0.0461828384104675 | COAD | Male-baised eQTL |
| rs2635326 | chr4:117518538:A:G | - | -0.0713553484828481 | 0.0461828384104675 | COAD | Male-baised eQTL |
| rs17626479 | chr4:118208300:C:A | - | 0.118373934880786 | 0.0463131858776276 | COAD | Male-baised eQTL |
| rs1948254 | chr4:117544884:A:G | - | -0.0686780729795298 | 0.0463759172813835 | COAD | Male-baised eQTL |
| rs1948252 | chr4:117545460:G:C | - | -0.0686780729795298 | 0.0463759172813835 | COAD | Male-baised eQTL |
| rs6533702 | chr4:113594094:A:G | gene | -0.080353924664283 | 0.0465867608804781 | COAD | Male-baised eQTL |
| rs1948217 | chr4:117553684:T:C | - | -0.0686765571709558 | 0.0469454914803704 | COAD | Male-baised eQTL |
| rs1948240 | chr4:117506392:T:C | - | -0.0701823234788239 | 0.0473873059073231 | COAD | Male-baised eQTL |
| rs2635361 | chr4:117508720:T:C | - | -0.0701187048802685 | 0.0477339232825546 | COAD | Male-baised eQTL |
| rs4131849 | chr4:117477239:A:G | - | -0.0735269726043282 | 0.0477981618801484 | COAD | Male-baised eQTL |
| rs1948246 | chr4:117534962:A:G | - | -0.0687928515446544 | 0.0485563985612032 | COAD | Male-baised eQTL |
| rs10029516 | chr4:113089932:G:T | - | -0.0720025568099554 | 0.0489094928467302 | COAD | Male-baised eQTL |
| rs1298631 | chr4:110871381:C:G | - | -0.0818711495834825 | 0.049541786529209 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000145349 |
| CpG Site: cg16503611 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.418960747092333 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg16503611 | chr4:113758605 | gene | -0.418960747092333 | 5.11249941833089e-08 | -0.40154241145453595 | 4.354901667941827e-10 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9307401 | chr4:114239320:T:C | Distant upstream | 0.0183432763209694 | 0.0042031879561922 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1603621 | chr4:114242063:G:A | Distant upstream | 0.0183432763209694 | 0.0042031879561922 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2646652 | chr4:114245268:T:C | Distant upstream | 0.0183432763209694 | 0.0042031879561922 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13435251 | chr4:114237534:C:T | Distant upstream | 0.0182050628783518 | 0.00441723521328253 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670209 | chr4:114233164:A:G | Distant upstream | -0.0207454586320481 | 0.00542432273510569 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670264 | chr4:114233569:G:T | Distant upstream | -0.0207454586320481 | 0.00542432273510569 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670268 | chr4:114234727:T:G | Distant upstream | -0.0207458886439509 | 0.00548410238071121 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12649732 | chr4:114233781:A:G | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670267 | chr4:114234080:G:A | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs56392133 | chr4:114235323:G:T | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9790616 | chr4:114236830:C:T | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9790617 | chr4:114236898:G:A | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9790350 | chr4:114236907:A:G | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs60339288 | chr4:114237812:C:T | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs55972564 | chr4:114237912:G:A | Distant upstream | -0.0206690069470388 | 0.0056962346270187 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497592 | chr4:114238106:T:A | Distant upstream | 0.0178993732622834 | 0.00590042222821114 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1603622 | chr4:114240824:A:G | Distant upstream | 0.0178345645808456 | 0.00661472669165488 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670263 | chr4:114233374:A:G | Distant upstream | -0.0205085725602149 | 0.00664389646972295 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12650827 | chr4:114233652:T:G | Distant upstream | -0.020431896557258 | 0.00697256980568824 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12641578 | chr4:114233676:A:T | Distant upstream | -0.020431896557258 | 0.00697256980568824 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12650835 | chr4:114233689:T:G | Distant upstream | -0.020431896557258 | 0.00697256980568824 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670276 | chr4:114240141:C:T | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs57570419 | chr4:114240286:C:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs201813771 | chr4:114240314:G:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs58998981 | chr4:114240355:A:G | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs61195404 | chr4:114240463:C:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9790773 | chr4:114241449:G:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9790774 | chr4:114241568:G:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670280 | chr4:114241861:G:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs55938981 | chr4:114242145:A:C | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs56386416 | chr4:114242310:T:G | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs55651417 | chr4:114242349:A:G | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670284 | chr4:114243119:G:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670285 | chr4:114243636:T:C | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs74889587 | chr4:114243691:G:A | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670286 | chr4:114243802:C:T | Distant upstream | -0.0203669638358643 | 0.00747233914629002 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs10023121 | chr4:114139321:C:A | Distant upstream | 0.0175046448595885 | 0.00831956943612015 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs6840229 | chr4:114143455:G:A | Distant upstream | 0.0175046448595885 | 0.00831956943612015 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1112494 | chr4:114154887:T:A | Distant upstream | 0.0169292654274894 | 0.0085755640809202 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7670719 | chr4:114159203:A:T | Distant upstream | 0.0171540827734241 | 0.0103122927748965 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497591 | chr4:114137962:A:G | Distant upstream | 0.0169784894109312 | 0.0116026994762901 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs28728398 | chr4:114133815:A:G | Distant upstream | 0.0171720529580395 | 0.0116299900561414 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs10029688 | chr4:114134544:A:G | Distant upstream | 0.0171720529580395 | 0.0116299900561414 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2173251 | chr4:114136048:C:A | Distant upstream | 0.0171720529580395 | 0.0116299900561414 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7670220 | chr4:114155697:T:C | Distant upstream | 0.0169706492143919 | 0.0116767077201431 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497590 | chr4:114157138:T:C | Distant upstream | 0.0169706492143919 | 0.0116767077201431 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7683312 | chr4:114157667:T:C | Distant upstream | 0.0169706492143919 | 0.0116767077201431 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs4446395 | chr4:114137070:G:A | Distant upstream | 0.0169504383728729 | 0.0126770803100752 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9790468 | chr4:114298377:G:C | Distant upstream | 0.0202602412637808 | 0.0127370654797012 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1846091 | chr4:114131035:G:A | Distant upstream | 0.0168423601823488 | 0.0127945056798949 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs6854583 | chr4:114132729:A:C | Distant upstream | 0.0166386302807103 | 0.0130441683754083 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1391183 | chr4:114172562:C:T | Distant upstream | 0.0167537914260347 | 0.0134717370704657 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13120257 | chr4:114163499:G:A | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2088413 | chr4:114164831:A:T | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1472418 | chr4:114165014:A:G | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1909020 | chr4:114170003:T:C | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs10857023 | chr4:114170344:G:C | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497588 | chr4:114171585:C:T | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7681305 | chr4:114172906:G:T | Distant upstream | 0.016740659472123 | 0.0135914670979134 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs28502715 | chr4:114305096:T:G | Distant upstream | 0.0204480319116123 | 0.0139132961150581 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs28592242 | chr4:114245609:A:G | Distant upstream | 0.0169180963805649 | 0.0143543836523669 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs36045069 | chr4:114139153:G:A | Distant upstream | 0.016882753704783 | 0.0148962041136664 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs111315176 | chr4:114231138:A:C | Distant upstream | -0.0196144558480028 | 0.0151394032735588 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670205 | chr4:114231391:A:G | Distant upstream | -0.0196144558480028 | 0.0151394032735588 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670206 | chr4:114231790:G:A | Distant upstream | -0.0196144558480028 | 0.0151394032735588 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs57993822 | chr4:114232058:T:A | Distant upstream | -0.0196144558480028 | 0.0151394032735588 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13144118 | chr4:114195781:T:G | Distant upstream | 0.0166288031778268 | 0.0151457057456097 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9684974 | chr4:114107131:G:A | Distant upstream | 0.0163867802688047 | 0.015477892870147 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9684256 | chr4:114110665:A:G | Distant upstream | 0.0163867802688047 | 0.015477892870147 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1553064 | chr4:114116462:G:A | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs34643012 | chr4:114117652:G:A | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs17046836 | chr4:114118593:C:G | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12499066 | chr4:114119023:G:A | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497599 | chr4:114122422:T:C | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs35432805 | chr4:114123047:C:T | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2892642 | chr4:114133102:A:G | Distant upstream | 0.0163749697410702 | 0.0156247105287381 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12499744 | chr4:114125011:C:T | Distant upstream | 0.0163594819151828 | 0.0158325193522118 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12503964 | chr4:114104525:C:G | Distant upstream | 0.0165398661919101 | 0.01595469441706 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs140008710 | chr4:114151152:G:A | Distant upstream | 0.0163480863531822 | 0.0162195916795226 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2388935 | chr4:114099471:C:G | Distant upstream | 0.0165456958291152 | 0.0162206384636995 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs17484977 | chr4:114160538:T:C | Distant upstream | 0.0161288271501699 | 0.0176761068997044 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2388934 | chr4:114099472:C:T | Distant upstream | 0.0164393546202609 | 0.0186587681854242 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs28812617 | chr4:114300346:C:T | Distant upstream | 0.0200056244268329 | 0.0188127803772136 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs62316089 | chr4:114152490:C:T | Distant upstream | 0.0161605843641243 | 0.0217432950808116 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs4499760 | chr4:114151746:G:A | Distant upstream | 0.016196819822707 | 0.0223861470689624 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13105870 | chr4:114124307:G:A | Distant upstream | 0.0158909303014428 | 0.0228771145899208 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9307402 | chr4:114248280:A:G | Distant upstream | 0.0161923733781046 | 0.0233207068603823 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9992414 | chr4:114154394:G:A | Distant upstream | 0.0166315680442861 | 0.0240917465477629 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2388973 | chr4:114164840:T:C | Distant upstream | 0.0166309025933496 | 0.0241035427159878 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497589 | chr4:114171545:T:C | Distant upstream | 0.0166309025933496 | 0.0241035427159878 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2132932 | chr4:114107996:C:G | Distant upstream | 0.0165065750738532 | 0.0250582899654267 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2388933 | chr4:114106060:A:G | Distant upstream | 0.0156794772239062 | 0.0261002313686792 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs9684970 | chr4:114107095:G:A | Distant upstream | 0.0156794772239062 | 0.0261002313686792 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs17581982 | chr4:114117258:C:G | Distant upstream | 0.0156648245563947 | 0.0264098147228208 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497604 | chr4:114126400:T:G | Distant upstream | 0.0155873982037504 | 0.0265121920810278 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497606 | chr4:114126659:C:A | Distant upstream | 0.0155873982037504 | 0.0265121920810278 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497605 | chr4:114126423:A:C | Distant upstream | 0.0156458131390698 | 0.0268058292110683 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13107713 | chr4:114149335:C:T | Distant upstream | 0.0159068754384474 | 0.0268906142720981 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs870413 | chr4:114096351:T:A | Distant upstream | 0.0157541557422658 | 0.0272399648379222 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2055231 | chr4:114160223:G:A | Distant upstream | 0.0153999100876262 | 0.0295482989755893 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs6819210 | chr4:114140382:C:A | Distant upstream | 0.0158507236756508 | 0.0295482989755893 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs55729205 | chr4:114142756:G:A | Distant upstream | 0.0158507236756508 | 0.0295482989755893 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13112771 | chr4:114146144:T:C | Distant upstream | 0.0158507236756508 | 0.0295482989755893 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12503476 | chr4:114146418:A:T | Distant upstream | 0.0158507236756508 | 0.0295482989755893 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12499956 | chr4:114146536:T:G | Distant upstream | 0.0158507236756508 | 0.0295482989755893 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497586 | chr4:114174020:G:A | Distant upstream | 0.0155600420596649 | 0.0332039345574586 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670291 | chr4:114247215:C:T | Distant upstream | -0.0177615318979148 | 0.0337635504674613 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs72670292 | chr4:114247380:C:A | Distant upstream | -0.0177615318979148 | 0.0337635504674613 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2646645 | chr4:114248092:C:T | Distant upstream | -0.0177615318979148 | 0.0337635504674613 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2646646 | chr4:114248105:T:C | Distant upstream | -0.0177615318979148 | 0.0337635504674613 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2725524 | chr4:114248127:T:G | Distant upstream | -0.0177615318979148 | 0.0337635504674613 | LUAD | Female-baised sQTL |
| exon_skip_431905 | chr4:113455725:113455821 | 5CDS-5UTR | rs10026877 | chr4:113708786:G:A | Distant upstream | -0.0307693542367469 | 0.0337830724881774 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7675296 | chr4:114104866:C:T | Distant upstream | 0.015339126547932 | 0.0340900358722741 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs35086286 | chr4:114151980:C:G | Distant upstream | 0.015278724299684 | 0.0346120606943341 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13110634 | chr4:114232627:A:T | Distant upstream | 0.0154409673282253 | 0.0350768935041382 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13434807 | chr4:114240153:A:G | Distant upstream | 0.0155482183641072 | 0.035305923355132 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs10000836 | chr4:114248290:T:C | Distant upstream | 0.0155482183641072 | 0.035305923355132 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs35796752 | chr4:114175771:A:G | Distant upstream | 0.0154575370418841 | 0.0353224277054761 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs996109 | chr4:114246586:T:C | Distant upstream | -0.0176663808214397 | 0.0363008150266662 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs996108 | chr4:114246611:C:A | Distant upstream | -0.0176663808214397 | 0.0363008150266662 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs996107 | chr4:114246682:G:A | Distant upstream | -0.0176663808214397 | 0.0363008150266662 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2725520 | chr4:114246792:A:C | Distant upstream | -0.0176663808214397 | 0.0363008150266662 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs36041177 | chr4:114235482:C:T | Distant upstream | 0.0156508002723567 | 0.0364620867729084 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs6813945 | chr4:114197705:G:T | Distant upstream | 0.0154023688297625 | 0.0373324964437222 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2388971 | chr4:114162471:C:G | Distant upstream | 0.0161686921602249 | 0.0382388105408039 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2388972 | chr4:114162472:C:G | Distant upstream | 0.0161686921602249 | 0.0382388105408039 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs6832117 | chr4:114163010:T:C | Distant upstream | 0.0161686921602249 | 0.0382388105408039 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2646643 | chr4:114247791:C:T | Distant upstream | -0.0176087903760387 | 0.0387767431206362 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12503807 | chr4:114229056:G:A | Distant upstream | 0.0153085112051207 | 0.0405793213419148 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497585 | chr4:114178002:G:A | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs6850855 | chr4:114180154:C:A | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497584 | chr4:114180617:A:G | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1391182 | chr4:114188320:G:A | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7685626 | chr4:114189499:G:T | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs12499813 | chr4:114189958:G:A | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2036168 | chr4:114190938:C:T | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2036167 | chr4:114191213:T:C | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2036166 | chr4:114192446:G:A | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497583 | chr4:114193527:A:G | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1497581 | chr4:114193617:G:A | Distant upstream | 0.0152108299836529 | 0.040750628533671 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs13117364 | chr4:114195745:G:C | Distant upstream | 0.0153212459980845 | 0.0413548826527744 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs10014146 | chr4:114248851:A:G | Distant upstream | -0.0170953320674339 | 0.0441279656703662 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs4624720 | chr4:114224430:A:G | Distant upstream | 0.0151841349091253 | 0.0492595272744695 | LUAD | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs73843474 | chr4:113676899:T:C | Distant upstream | -0.034229258640997 | 0.0268625172184018 | LGG | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs1029469 | chr4:113683116:T:C | Distant upstream | -0.034229258640997 | 0.0268625172184018 | LGG | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs7678109 | chr4:113670907:A:G | Distant upstream | -0.0321858839252351 | 0.0465055544025217 | LGG | Female-baised sQTL |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs56249002 | chr4:113679143:T:C | Distant upstream | -0.0320325310566402 | 0.0495177097458789 | LGG | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_431911 | chr4:113500462:113500511 | Frame-shift | rs2888764 | chr4:113927620:C:T | Distant upstream | -0.0392348320810819 | 0.0290206656402741 | LUAD | Male-baised sQTL |
| exon_skip_431905 | chr4:113455725:113455821 | 5CDS-5UTR | rs11936521 | chr4:113207919:C:A | Distant downstream | 0.0321598615962485 | 0.0416576351579937 | LUAD | Male-baised sQTL |
| exon_skip_431905 | chr4:113455725:113455821 | 5CDS-5UTR | rs56703021 | chr4:113681798:C:T | Distant upstream | 0.047931784124807 | 0.00792644064273057 | LGG | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of CAMK2D |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000145349 | CAMK2D | C0004238 | Atrial Fibrillation | 2 | CTD_human |
| ENSG00000145349 | CAMK2D | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| ENSG00000145349 | CAMK2D | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| ENSG00000145349 | CAMK2D | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| ENSG00000145349 | CAMK2D | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
| ENSG00000145349 | CAMK2D | C1136382 | Sclerocystic Ovaries | 1 | CTD_human |
| ENSG00000145349 | CAMK2D | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
| ENSG00000145349 | CAMK2D | C3468561 | familial atrial fibrillation | 2 | CTD_human |
