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Gene: ENSG00000144354 |
Summary for CDCA7 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000144354 | Gene symbol | CDCA7 |
| Gene name | cell division cycle associated 7 | |
| HGNC | 14628 | |
| Entrez ID | 83879 | |
| Gene type | protein_coding | |
| Synonyms | CDCA7|FLJ14736|JPO1 | |
| UniProtAcc | Q9BWT1 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for CDCA7 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CDCA7 | 6.63e+02 | -1.84e+00 | 5.14e-01 | -3.57e+00 | 3.54e-04 | 5.33e-03 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CDCA7 | 1.49e+03 | 1.05e+00 | 1.86e-01 | 5.66e+00 | 1.50e-08 | 7.38e-08 | HNSC |
| CDCA7 | 4.16e+03 | 1.96e+00 | 3.82e-01 | 5.14e+00 | 2.72e-07 | 8.13e-06 | ESCA |
| CDCA7 | 3.27e+02 | 5.03e+00 | 6.31e-01 | 7.97e+00 | 1.58e-15 | 7.15e-14 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CDCA7 | 2.74e+02 | 3.30e+00 | 5.06e-01 | 6.51e+00 | 7.45e-11 | 4.39e-09 | KIRP |
| CDCA7 | 6.31e+02 | 1.37e+00 | 1.71e-01 | 8.05e+00 | 8.50e-16 | 2.41e-15 | BRCA |
| CDCA7 | 5.36e+03 | 1.79e+00 | 2.72e-01 | 6.59e+00 | 4.44e-11 | 1.34e-09 | READ |
Top |
Sex-biased somatic mutation for CDCA7 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for CDCA7 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| THCA | cg21583565 | chr2:173354608 | CGI:chr2:173354805-173355640 | promoter | 1.44e-01 | 4.37e-02 | 2.74e+00 | 6.14e-03 | 1.17e-02 | 1.00e-01 |
| LIHC | cg24776469 | chr2:173354620 | CGI:chr2:173354805-173355640 | promoter | 2.68e-01 | 1.06e-01 | 2.30e+00 | 2.17e-02 | 2.40e-02 | 1.62e-01 |
| LIHC | cg24937696 | chr2:173354806 | CGI:chr2:173354805-173355640 | promoter | 2.32e-01 | 5.35e-02 | 2.80e+00 | 5.18e-03 | 6.81e-03 | 1.78e-01 |
| LIHC | cg21583565 | chr2:173354608 | CGI:chr2:173354805-173355640 | promoter | 3.94e-01 | 2.42e-01 | 2.13e+00 | 3.30e-02 | 3.47e-02 | 1.51e-01 |
| LIHC | cg13484295 | chr2:173355358 | CGI:chr2:173354805-173355640 | promoter,gene body | 2.68e-01 | 9.16e-02 | 2.68e+00 | 7.35e-03 | 9.27e-03 | 1.76e-01 |
| CHOL | cg07302848 | chr2:173354774 | CGI:chr2:173354805-173355640 | promoter | 1.33e-01 | 2.57e-01 | -2.58e+00 | 9.87e-03 | 2.15e-02 | -1.24e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg24776469 | chr2:173354620 | CGI:chr2:173354805-173355640 | promoter | 1.45e-01 | 3.66e-02 | 3.02e+00 | 2.51e-03 | 3.11e-03 | 1.08e-01 |
| BRCA | cg21583565 | chr2:173354608 | CGI:chr2:173354805-173355640 | promoter | 1.93e-01 | 3.77e-02 | 2.52e+00 | 1.17e-02 | 1.30e-02 | 1.55e-01 |
Top |
Exon skipping events with PSI in TCGA for CDCA7 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for CDCA7 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for CDCA7 |
| TFs related to CDCA7. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | ZNF879 | CDCA7 | 3.81e+00 | 9.80e-01 | 2.61e+00 | 3.83e-03 | Male-biased |
| DLBC | ZNF418 | CDCA7 | 2.87e+00 | 4.21e-03 | 3.99e+00 | 9.81e-01 | Female-biased |
| LAML | ZNF334 | CDCA7 | 4.36e+00 | 9.81e-01 | 3.39e+00 | 7.93e-03 | Male-biased |
| PAAD | EMX1 | CDCA7 | 4.52e+00 | 9.81e-01 | 3.72e+00 | 1.20e-02 | Male-biased |
| PAAD | EMX2 | CDCA7 | 4.41e+00 | 9.81e-01 | 3.59e+00 | 1.06e-02 | Male-biased |
| PAAD | FOXF2 | CDCA7 | 4.55e+00 | 9.83e-01 | 3.74e+00 | 1.10e-02 | Male-biased |
| PAAD | HOXC10 | CDCA7 | 4.12e+00 | 9.82e-01 | 3.18e+00 | 5.64e-03 | Male-biased |
| PAAD | POU6F2 | CDCA7 | 4.68e+00 | 9.88e-01 | 3.79e+00 | 7.23e-03 | Male-biased |
| PAAD | ZNF334 | CDCA7 | 4.04e+00 | 9.86e-01 | 2.71e+00 | 7.13e-04 | Male-biased |
| PAAD | ZNF418 | CDCA7 | 3.87e+00 | 9.81e-01 | 2.57e+00 | 8.41e-04 | Male-biased |
| CDCA7 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for CDCA7 |
| RBPs related to ES in CDCA7. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| COAD | G3BP2 | exon_skip_331265 | 9.29e+00 | 9.82e-01 | 8.99e+00 | 1.52e-02 | Male-biased |
| CDCA7 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000144354 | AC106037.2,hsa-mir-93,CDCA7 | Male-specific ceRNA | TCGA-HNSC |
| ENSG00000144354 | LINC01409,hsa-mir-93,CDCA7 | Male-specific ceRNA | TCGA-HNSC |
| ENSG00000144354 | AL022322.2,hsa-mir-93,CDCA7 | Male-specific ceRNA | TCGA-HNSC |
| ENSG00000144354 | AC004943.2,hsa-mir-93,CDCA7 | Male-specific ceRNA | TCGA-HNSC |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17701274 | chr2:173443917:T:C | - | 0.140724214481449 | 0.0032342581374678 | LIHC | Female-baised eQTL |
| rs72946199 | chr2:177299036:T:C | - | 0.11205914508272 | 0.0019232934061484 | KIRC | Female-baised eQTL |
| rs72948115 | chr2:177302358:C:T | - | 0.11205914508272 | 0.0019232934061484 | KIRC | Female-baised eQTL |
| rs55945003 | chr2:177343779:C:T | - | 0.103266271307901 | 0.0059750702642873 | KIRC | Female-baised eQTL |
| rs2120687 | chr2:177174306:A:C | - | 0.111173421719857 | 0.0117496247944507 | KIRC | Female-baised eQTL |
| rs56239626 | chr2:177171622:G:A | - | 0.112861980103406 | 0.0173636076102542 | KIRC | Female-baised eQTL |
| rs3109082 | chr2:177155719:T:G | - | 0.105755387264547 | 0.0193155933662801 | KIRC | Female-baised eQTL |
| rs155087 | chr2:181476947:T:C | - | -0.0455114249523338 | 0.0289374119397775 | LUAD | Female-baised eQTL |
| rs155088 | chr2:181476990:C:G | - | -0.0455114249523338 | 0.0289374119397775 | LUAD | Female-baised eQTL |
| rs155090 | chr2:181477185:G:C | - | -0.0455114249523338 | 0.0289374119397775 | LUAD | Female-baised eQTL |
| rs155096 | chr2:181480662:A:G | - | -0.0433585043120853 | 0.045187058312697 | LUAD | Female-baised eQTL |
| rs155095 | chr2:181478551:A:G | - | -0.0429967263250731 | 0.0455195890894011 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs77607489 | chr2:169480335:T:A | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs12614103 | chr2:169482171:A:G | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs75246169 | chr2:169487436:T:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs116869010 | chr2:169487683:T:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs77749686 | chr2:169495149:T:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs115874575 | chr2:169497184:G:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs114452964 | chr2:169500083:C:G | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs12615476 | chr2:169501683:C:T | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs181495249 | chr2:169505191:G:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs189448631 | chr2:169505372:G:A | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs182027521 | chr2:169505686:C:T | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs186068899 | chr2:169505786:G:A | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs370773265 | chr2:169505900:C:G | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs142813498 | chr2:169506403:G:T | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs3754922 | chr2:169507725:T:G | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs114403621 | chr2:169508106:T:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs3769772 | chr2:169512185:T:C | - | 0.121250298326041 | 0.047269331792837 | LIHC | Male-baised eQTL |
| rs78198178 | chr2:169493440:A:G | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs114404270 | chr2:169495941:T:C | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs190280661 | chr2:169496786:G:A | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs74715514 | chr2:169497486:C:G | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs80312049 | chr2:169500250:T:G | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs116729322 | chr2:169502485:T:G | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs58194973 | chr2:169503467:A:G | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs7587839 | chr2:169503887:C:T | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs183253343 | chr2:169506344:C:T | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs17524024 | chr2:169508867:T:C | - | 0.121027446284127 | 0.0482406595827083 | LIHC | Male-baised eQTL |
| rs75945667 | chr2:170202904:A:G | - | 0.0680433027436163 | 0.0499249220157854 | LIHC | Male-baised eQTL |
| rs7602862 | chr2:165267504:T:C | - | 0.0645933427905142 | 0.0271673723391008 | LGG | Male-baised eQTL |
| rs35513078 | chr2:165248177:A:G | - | 0.0623883747147452 | 0.0400532879545251 | LGG | Male-baised eQTL |
| rs4667799 | chr2:165233603:A:G | - | 0.0613357182823201 | 0.046776315271646 | LGG | Male-baised eQTL |
| rs12468801 | chr2:165246030:C:T | - | 0.0613357182823201 | 0.046776315271646 | LGG | Male-baised eQTL |
| rs11896706 | chr2:166136524:T:C | - | 0.0318659840697212 | 0.0367425238003557 | KIRC | Male-baised eQTL |
| rs11897944 | chr2:175630998:C:A | - | 0.0372327623261515 | 0.0408399293467363 | KIRC | Male-baised eQTL |
| rs2390319 | chr2:165964896:A:G | - | 0.0520060844899664 | 0.00870202513346984 | LUAD | Male-baised eQTL |
| rs56269580 | chr2:165972379:G:C | - | 0.0520060844899664 | 0.00870202513346984 | LUAD | Male-baised eQTL |
| rs10201659 | chr2:165977160:G:A | - | 0.0509536961960168 | 0.0106668770658067 | LUAD | Male-baised eQTL |
| rs10166902 | chr2:165977302:T:G | - | 0.0509536961960168 | 0.0106668770658067 | LUAD | Male-baised eQTL |
| rs28363818 | chr2:165959150:A:G | - | 0.0502862190430667 | 0.015305115781878 | LUAD | Male-baised eQTL |
| rs76128279 | chr2:172446275:T:C | - | 0.0716893561759229 | 0.0156361962474677 | LUAD | Male-baised eQTL |
| rs113283900 | chr2:170420012:A:G | - | 0.055462969649166 | 0.0157989826590201 | LUAD | Male-baised eQTL |
| rs10221583 | chr2:165957859:G:A | - | 0.0503361503096788 | 0.0158025507472223 | LUAD | Male-baised eQTL |
| rs17607736 | chr2:170427218:C:T | - | 0.0553799380534995 | 0.0159236665263194 | LUAD | Male-baised eQTL |
| rs60384579 | chr2:170415769:C:G | - | 0.0556557526018833 | 0.0160871901034669 | LUAD | Male-baised eQTL |
| rs9711634 | chr2:172445372:G:A | - | 0.0693290527627182 | 0.0175506268332602 | LUAD | Male-baised eQTL |
| rs4993283 | chr2:172445603:T:C | - | 0.0693290527627182 | 0.0175506268332602 | LUAD | Male-baised eQTL |
| rs4993282 | chr2:172445628:G:A | - | 0.0693290527627182 | 0.0175506268332602 | LUAD | Male-baised eQTL |
| rs4480959 | chr2:172445817:C:T | - | 0.0693290527627182 | 0.0175506268332602 | LUAD | Male-baised eQTL |
| rs10197251 | chr2:172452682:C:A | - | 0.0697939413829068 | 0.0190669355637319 | LUAD | Male-baised eQTL |
| rs75397932 | chr2:172446361:A:G | - | 0.0694075585139104 | 0.0204408429418585 | LUAD | Male-baised eQTL |
| rs6737259 | chr2:175478576:T:G | - | 0.0428016204841864 | 0.0209670115621892 | LUAD | Male-baised eQTL |
| rs1375180 | chr2:176502699:A:C | - | 0.0411349997285621 | 0.0209968901071992 | LUAD | Male-baised eQTL |
| rs10930752 | chr2:176768076:G:T | - | 0.0378423015265788 | 0.0214580606503992 | LUAD | Male-baised eQTL |
| rs994398 | chr2:166049259:C:G | - | 0.0520778379537899 | 0.0230630316030751 | LUAD | Male-baised eQTL |
| rs12470105 | chr2:166049775:A:G | - | 0.0520778379537899 | 0.0230630316030751 | LUAD | Male-baised eQTL |
| rs13408393 | chr2:176504050:G:A | - | 0.0399301120080976 | 0.0244463592557111 | LUAD | Male-baised eQTL |
| rs13408200 | chr2:176504051:C:T | - | 0.0399301120080976 | 0.0244463592557111 | LUAD | Male-baised eQTL |
| rs7568419 | chr2:176505791:A:C | - | 0.0399301120080976 | 0.0244463592557111 | LUAD | Male-baised eQTL |
| rs16822821 | chr2:166057955:C:T | - | 0.0470204357899182 | 0.0250236323796952 | LUAD | Male-baised eQTL |
| rs57251863 | chr2:175427217:C:T | - | 0.0427152043070511 | 0.025074941049217 | LUAD | Male-baised eQTL |
| rs4668259 | chr2:170430014:T:G | - | 0.0526162846347449 | 0.026928483379118 | LUAD | Male-baised eQTL |
| rs1370934 | chr2:170408317:T:C | - | -0.0612413105403746 | 0.0284872662097339 | LUAD | Male-baised eQTL |
| rs16863187 | chr2:175443909:A:C | - | 0.0421018607636015 | 0.0289520991284756 | LUAD | Male-baised eQTL |
| rs10460370 | chr2:175427132:T:C | - | 0.0420052930644551 | 0.0297635943726259 | LUAD | Male-baised eQTL |
| rs58999795 | chr2:175434705:C:G | - | 0.0420296682496654 | 0.0297913147563773 | LUAD | Male-baised eQTL |
| rs73973834 | chr2:175435283:T:C | - | 0.0420296682496654 | 0.0297913147563773 | LUAD | Male-baised eQTL |
| rs73973835 | chr2:175435297:T:G | - | 0.0420296682496654 | 0.0297913147563773 | LUAD | Male-baised eQTL |
| rs10497276 | chr2:166000490:C:A | - | 0.0504689940536165 | 0.0323991594029569 | LUAD | Male-baised eQTL |
| rs16851356 | chr2:166004124:T:C | - | 0.0504689940536165 | 0.0323991594029569 | LUAD | Male-baised eQTL |
| rs12464461 | chr2:170406200:A:C | - | -0.0414488528425101 | 0.0362210865121014 | LUAD | Male-baised eQTL |
| rs4088148 | chr2:170406416:T:C | - | -0.0414488528425101 | 0.0362210865121014 | LUAD | Male-baised eQTL |
| rs4893874 | chr2:176516057:G:A | - | 0.0396616845446127 | 0.0380494724868796 | LUAD | Male-baised eQTL |
| rs16851327 | chr2:165985037:A:C | - | 0.0493195194955582 | 0.0400930641735842 | LUAD | Male-baised eQTL |
| rs79907501 | chr2:165987175:C:G | - | 0.0493195194955582 | 0.0400930641735842 | LUAD | Male-baised eQTL |
| rs10497275 | chr2:165990220:A:G | - | 0.0493195194955582 | 0.0400930641735842 | LUAD | Male-baised eQTL |
| rs4243394 | chr2:176525139:A:G | - | 0.0397062794757888 | 0.0402279400332859 | LUAD | Male-baised eQTL |
| rs143662035 | chr2:165975454:T:C | - | 0.0501987491521657 | 0.0407301945393434 | LUAD | Male-baised eQTL |
| rs2217195 | chr2:165975554:A:T | - | 0.0501987491521657 | 0.0407301945393434 | LUAD | Male-baised eQTL |
| rs57244097 | chr2:165948274:G:A | - | 0.0513135545479775 | 0.042452593213002 | LUAD | Male-baised eQTL |
| rs6758766 | chr2:176765880:T:G | - | 0.0354299655856215 | 0.0436220555257304 | LUAD | Male-baised eQTL |
| rs4600700 | chr2:176766136:G:T | - | 0.0354299655856215 | 0.0436220555257304 | LUAD | Male-baised eQTL |
| rs11680819 | chr2:165956405:T:C | - | 0.0499053343109178 | 0.048691811425368 | LUAD | Male-baised eQTL |
| rs12614431 | chr2:166031502:A:G | - | 0.0494806587444232 | 0.0490980795302758 | LUAD | Male-baised eQTL |
| rs113164940 | chr2:169738337:C:T | - | -0.0824486101915507 | 0.0283798247050443 | COAD | Male-baised eQTL |
| rs67500252 | chr2:169733592:G:A | - | -0.0818448720530896 | 0.0290896275595639 | COAD | Male-baised eQTL |
| rs72891403 | chr2:169737391:C:T | - | -0.0818448720530896 | 0.0290896275595639 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000144354 |
| CpG Site: cg21622202 | |
| Position to Gene: gene,CDS,UTR,exon,enhancer | |
| Male Effect: -0.470126007442241 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg21622202 | chr2:173359434 | gene,CDS,UTR,exon,enhancer | -0.470126007442241 | 2.69394788245075e-28 | -0.6890518689338303 | 9.670319431708808e-33 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of CDCA7 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000144354 | CDCA7 | C2931456 | Prostate cancer, familial | 1 | CTD_human |
| ENSG00000144354 | CDCA7 | C4310799 | IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME 3 | 1 | CTD_human |
| ENSG00000144354 | CDCA7 | C4722327 | PROSTATE CANCER, HEREDITARY, 1 | 1 | CTD_human |
