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Gene: ENSG00000143799 |
Summary for PARP1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000143799 | Gene symbol | PARP1 |
| Gene name | poly(ADP-ribose) polymerase 1 | |
| HGNC | 270 | |
| Entrez ID | 142 | |
| Gene type | protein_coding | |
| Synonyms | PARP1|PARP|ARTD1|Poly-PARP|PARS | |
| UniProtAcc | P09874 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000143799 | PARP1 | DB00277 | Theophylline | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB01593 | Zinc | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB02498 | Carba-nicotinamide-adenine-dinucleotide | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB02690 | NU1025 | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB02701 | Nicotinamide | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB03072 | 2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB03073 | 3-Methoxybenzamide | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB03509 | 2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB03722 | 3,4-Dihydro-5-Methyl-Isoquinolinone | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB04010 | 2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB07096 | 6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB07232 | Veliparib | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB07330 | A-620223 | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB07787 | 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB09074 | Olaparib | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB11760 | Talazoparib | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB11793 | Niraparib | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB12332 | Rucaparib | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB13877 | Iniparib | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB14487 | Zinc acetate | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB14533 | Zinc chloride | SmallMoleculeDrug |
| ENSG00000143799 | PARP1 | DB14548 | Zinc sulfate, unspecified form | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
| ENSG00000143799 | PARP1 | DB09074 | Olaparib | SmallMoleculeDrug | Treat Breast Cancer,Ovarian, Fallopian Tube, or Primary Peritoneal Cancer,Pancreatic Cancer,Prostate Cancer |
| ENSG00000143799 | PARP1 | DB11760 | Talazoparib | SmallMoleculeDrug | Treat Breast Cancer |
| ENSG00000143799 | PARP1 | DB11793 | Niraparib | SmallMoleculeDrug | Ovarian, Fallopian Tube, or Primary Peritoneal Cancer |
| ENSG00000143799 | PARP1 | DB12332 | Rucaparib | SmallMoleculeDrug | Ovarian, Fallopian Tube, or Primary Peritoneal Cancer |
Top |
Structure and expression level for PARP1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PARP1 | 1.67e+04 | 1.18e+00 | 5.51e-02 | 2.14e+01 | 8.01e-102 | 3.25e-100 | BRCA |
Top |
Sex-biased somatic mutation for PARP1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PARP1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg18764804 | chr1:226408967 | CGI:chr1:226407632-226408238 | promoter | 7.25e-01 | 6.04e-01 | 2.37e+00 | 1.79e-02 | 3.35e-02 | 1.21e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg18764804 | chr1:226408967 | CGI:chr1:226407632-226408238 | promoter | 7.14e-01 | 8.49e-01 | -3.33e+00 | 8.58e-04 | 1.59e-03 | -1.35e-01 |
| LUSC | cg02088626 | chr1:226408721 | CGI:chr1:226407632-226408238 | promoter | 7.59e-01 | 9.67e-01 | -3.73e+00 | 1.91e-04 | 9.47e-04 | -2.08e-01 |
| LUSC | cg18764804 | chr1:226408967 | CGI:chr1:226407632-226408238 | promoter | 7.06e-01 | 9.12e-01 | -4.10e+00 | 4.09e-05 | 5.36e-04 | -2.06e-01 |
| COAD | cg18764804 | chr1:226408967 | CGI:chr1:226407632-226408238 | promoter | 6.73e-01 | 7.87e-01 | -2.32e+00 | 2.05e-02 | 2.52e-02 | -1.14e-01 |
| BLCA | cg02088626 | chr1:226408721 | CGI:chr1:226407632-226408238 | promoter | 7.05e-01 | 9.41e-01 | -2.12e+00 | 3.42e-02 | 3.72e-02 | -2.36e-01 |
| BLCA | cg18764804 | chr1:226408967 | CGI:chr1:226407632-226408238 | promoter | 6.18e-01 | 8.51e-01 | -3.75e+00 | 1.75e-04 | 5.99e-04 | -2.33e-01 |
| LIHC | cg17127702 | chr1:226406622 | CGI:chr1:226407632-226408238 | promoter,gene body | 1.56e-01 | 2.64e-01 | -6.42e+00 | 1.40e-10 | 3.08e-09 | -1.08e-01 |
| KIRP | cg17127702 | chr1:226406622 | CGI:chr1:226407632-226408238 | promoter,gene body | 3.28e-01 | 4.80e-01 | -2.89e+00 | 3.87e-03 | 5.73e-03 | -1.52e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02088626 | chr1:226408721 | CGI:chr1:226407632-226408238 | promoter | 7.98e-01 | 9.04e-01 | 3.05e+00 | 2.32e-03 | 2.89e-03 | -1.06e-01 |
| BRCA | cg17127702 | chr1:226406622 | CGI:chr1:226407632-226408238 | promoter,gene body | 2.00e-01 | 4.62e-01 | -1.45e+01 | 1.29e-47 | 3.44e-44 | -2.63e-01 |
| BRCA | cg18764804 | chr1:226408967 | CGI:chr1:226407632-226408238 | promoter | 7.25e-01 | 8.66e-01 | -9.66e+00 | 4.68e-22 | 3.02e-21 | -1.40e-01 |
Top |
Exon skipping events with PSI in TCGA for PARP1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PARP1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PARP1 |
| TFs related to PARP1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| READ | ZNF235 | PARP1 | 4.02e+00 | 9.82e-01 | 1.64e+00 | 1.96e-05 | Male-biased |
| PARP1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PARP1 |
| RBPs related to ES in PARP1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ESRP2 | exon_skip_37638 | 8.69e+00 | 9.86e-01 | 8.24e+00 | 8.33e-03 | Male-biased |
| LUSC | ESRP2 | exon_skip_37638 | 8.35e+00 | 1.19e-02 | 8.69e+00 | 9.83e-01 | Female-biased |
| READ | ESRP2 | exon_skip_37638 | 8.32e+00 | 6.75e-03 | 8.69e+00 | 9.88e-01 | Female-biased |
| SARC | ESRP2 | exon_skip_37638 | 8.57e+00 | 9.84e-01 | 8.21e+00 | 1.02e-02 | Male-biased |
| PARP1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs74688907 | chr1:227380537:T:C | - | 0.0910518280825597 | 0.0134896016665988 | STAD | Female-baised eQTL |
| rs113442694 | chr1:227381406:A:T | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs75790780 | chr1:227381759:C:T | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs111314111 | chr1:227382137:C:T | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs75813302 | chr1:227384669:A:T | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs185245936 | chr1:227384678:A:C | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs79578285 | chr1:227385804:T:C | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs75322809 | chr1:227386120:T:C | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs78707022 | chr1:227387064:A:G | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs78469866 | chr1:227387323:G:A | - | 0.0907465773767496 | 0.0143183692542069 | STAD | Female-baised eQTL |
| rs111996994 | chr1:227379508:A:G | - | 0.0905830856875777 | 0.0145998365941117 | STAD | Female-baised eQTL |
| rs149129195 | chr1:227391118:C:T | - | 0.0905686460276687 | 0.0150050208230507 | STAD | Female-baised eQTL |
| rs143404897 | chr1:227391121:G:A | - | 0.0905686460276687 | 0.0150050208230507 | STAD | Female-baised eQTL |
| rs55643926 | chr1:227387928:C:T | - | 0.0872574804508896 | 0.0218335795650437 | STAD | Female-baised eQTL |
| rs73102394 | chr1:227388451:C:T | - | 0.0872574804508896 | 0.0218335795650437 | STAD | Female-baised eQTL |
| rs77116170 | chr1:227390016:C:A | - | 0.0870796628521429 | 0.0227091773079044 | STAD | Female-baised eQTL |
| rs115847858 | chr1:227390534:T:C | - | 0.0870796628521429 | 0.0227091773079044 | STAD | Female-baised eQTL |
| rs79505001 | chr1:227390601:C:T | - | 0.0870796628521429 | 0.0227091773079044 | STAD | Female-baised eQTL |
| rs6690332 | chr1:228750359:A:G | - | 0.105424861386812 | 0.0121640930536542 | LGG | Female-baised eQTL |
| rs79274749 | chr1:219327412:C:T | - | 0.113092780970233 | 0.0165392756474711 | LGG | Female-baised eQTL |
| rs75128958 | chr1:219309876:G:A | - | 0.111918502036106 | 0.0166406966827466 | LGG | Female-baised eQTL |
| rs76877325 | chr1:219310532:G:A | - | 0.111918502036106 | 0.0166406966827466 | LGG | Female-baised eQTL |
| rs115981387 | chr1:219316152:A:G | - | 0.111918502036106 | 0.0166406966827466 | LGG | Female-baised eQTL |
| rs76956800 | chr1:219316336:A:G | - | 0.111918502036106 | 0.0166406966827466 | LGG | Female-baised eQTL |
| rs72750036 | chr1:228705988:T:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs9725857 | chr1:228712499:T:C | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs60587333 | chr1:228716750:G:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs56119951 | chr1:228716766:G:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs72750044 | chr1:228720149:G:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs59441010 | chr1:228722597:G:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs61244026 | chr1:228723408:T:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs56232469 | chr1:228724483:G:A | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs113590475 | chr1:228726537:C:T | - | 0.104694726065333 | 0.0170751153900242 | LGG | Female-baised eQTL |
| rs78240542 | chr1:219380403:C:T | - | 0.107292932786522 | 0.0214196470390197 | LGG | Female-baised eQTL |
| rs17526867 | chr1:219384855:G:C | - | 0.107292932786522 | 0.0214196470390197 | LGG | Female-baised eQTL |
| rs79171852 | chr1:219390644:T:G | - | 0.107292932786522 | 0.0214196470390197 | LGG | Female-baised eQTL |
| rs79222190 | chr1:219392037:C:T | - | 0.107292932786522 | 0.0214196470390197 | LGG | Female-baised eQTL |
| rs79121954 | chr1:219399307:G:C | - | 0.10682575558903 | 0.026280841668025 | LGG | Female-baised eQTL |
| rs115428817 | chr1:219396934:G:A | - | 0.106510607125337 | 0.0273251893739507 | LGG | Female-baised eQTL |
| rs6675267 | chr1:228750274:C:T | - | 0.0971685772321938 | 0.0300428633268577 | LGG | Female-baised eQTL |
| rs75573203 | chr1:219396565:C:T | - | 0.103173254714444 | 0.0326835566854951 | LGG | Female-baised eQTL |
| rs78898838 | chr1:219396726:C:A | - | 0.103173254714444 | 0.0326835566854951 | LGG | Female-baised eQTL |
| rs74351907 | chr1:219380664:A:G | - | 0.100420147582767 | 0.0372503025021983 | LGG | Female-baised eQTL |
| rs72750037 | chr1:228706023:C:A | - | 0.0975064502072062 | 0.0377241124179731 | LGG | Female-baised eQTL |
| rs76430412 | chr1:219403518:C:T | - | 0.101333036034385 | 0.0464670965861618 | LGG | Female-baised eQTL |
| rs2273271 | chr1:228740687:G:A | - | 0.092638029628157 | 0.0487320146531524 | LGG | Female-baised eQTL |
| rs7545235 | chr1:228742541:G:A | - | 0.092638029628157 | 0.0487320146531524 | LGG | Female-baised eQTL |
| rs6426514 | chr1:228744368:G:A | - | 0.092638029628157 | 0.0487320146531524 | LGG | Female-baised eQTL |
| rs73113431 | chr1:231654602:T:C | - | 0.102959281276767 | 0.00108115848347917 | KIRC | Female-baised eQTL |
| rs9651121 | chr1:231671548:T:C | - | 0.0910368348193616 | 0.00504173091870564 | KIRC | Female-baised eQTL |
| rs518032 | chr1:233647965:G:T | - | 0.122887928240081 | 0.00317448501382699 | LUAD | Female-baised eQTL |
| rs521777 | chr1:233654106:G:T | - | 0.115656124482607 | 0.00827684461971626 | LUAD | Female-baised eQTL |
| rs10495278 | chr1:228126649:C:G | - | 0.115940341568869 | 0.0253552097399996 | LUAD | Female-baised eQTL |
| rs4653914 | chr1:228176857:A:T | - | 0.104001358586332 | 0.0333933259892333 | LUAD | Female-baised eQTL |
| rs28587961 | chr1:228179499:C:T | - | 0.103055268930757 | 0.0423894772473083 | LUAD | Female-baised eQTL |
| rs10916266 | chr1:228115347:A:C | - | 0.101948358353576 | 0.0465249345948349 | LUAD | Female-baised eQTL |
| rs78249617 | chr1:228116909:A:C | - | 0.101948358353576 | 0.0465249345948349 | LUAD | Female-baised eQTL |
| rs72742466 | chr1:218675403:A:G | - | 0.0409907463662251 | 0.0497853238036859 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7519548 | chr1:226449394:G:A | - | 0.0602543834634857 | 7.72081383359186e-05 | LGG | Male-baised eQTL |
| rs12743954 | chr1:217063637:T:C | - | 0.0676941213235309 | 0.000102612664233964 | LGG | Male-baised eQTL |
| rs7540059 | chr1:217063854:C:A | - | 0.0675280317799591 | 0.00011136799997735 | LGG | Male-baised eQTL |
| rs7530089 | chr1:236364941:A:G | - | 0.0609530113312578 | 0.000167703672218438 | LGG | Male-baised eQTL |
| rs12029336 | chr1:229152115:G:T | - | 0.0411475186742779 | 0.0034421476589916 | LGG | Male-baised eQTL |
| rs12066930 | chr1:219689589:C:A | - | 0.0524111002005838 | 0.00442528777347306 | LGG | Male-baised eQTL |
| rs12075578 | chr1:224355356:A:T | - | 0.0449142667448783 | 0.00468838666905316 | LGG | Male-baised eQTL |
| rs73093147 | chr1:229151702:G:A | - | 0.0395568663439571 | 0.00476885472796283 | LGG | Male-baised eQTL |
| rs9793447 | chr1:229151524:G:A | - | 0.0390210871142372 | 0.00559225437254726 | LGG | Male-baised eQTL |
| rs112543486 | chr1:229151832:C:G | - | 0.0390210871142372 | 0.00559225437254726 | LGG | Male-baised eQTL |
| rs10047091 | chr1:225899359:T:C | - | 0.047884875219101 | 0.00624692811335113 | LGG | Male-baised eQTL |
| rs12140423 | chr1:224375229:T:G | - | 0.0426333093282348 | 0.00901094318016197 | LGG | Male-baised eQTL |
| rs12128292 | chr1:224363891:G:A | - | 0.0426375769357007 | 0.00908723894514333 | LGG | Male-baised eQTL |
| rs12134167 | chr1:224369125:T:G | - | 0.0426375769357007 | 0.00908723894514333 | LGG | Male-baised eQTL |
| rs12120702 | chr1:224356329:G:A | - | 0.0399781689918792 | 0.00967592743862205 | LGG | Male-baised eQTL |
| rs10495220 | chr1:224387270:C:G | - | 0.0418893152680166 | 0.0107230955730336 | LGG | Male-baised eQTL |
| rs6684878 | chr1:224390685:C:T | - | 0.0418893152680166 | 0.0107230955730336 | LGG | Male-baised eQTL |
| rs12121977 | chr1:224412275:G:T | - | 0.0418893152680166 | 0.0107230955730336 | LGG | Male-baised eQTL |
| rs12124686 | chr1:224417394:C:T | - | 0.0418893152680166 | 0.0107230955730336 | LGG | Male-baised eQTL |
| rs12067076 | chr1:219010791:T:C | - | 0.0355300473150834 | 0.0112313223680355 | LGG | Male-baised eQTL |
| rs11118191 | chr1:218993024:G:A | - | 0.0334690685076496 | 0.0193056339225336 | LGG | Male-baised eQTL |
| rs7556027 | chr1:218993781:A:G | - | 0.0334690685076496 | 0.0193056339225336 | LGG | Male-baised eQTL |
| rs2184887 | chr1:218994496:A:G | - | 0.0334690685076496 | 0.0193056339225336 | LGG | Male-baised eQTL |
| rs11804604 | chr1:227838907:G:A | - | 0.0402134583381815 | 0.0195631518585095 | LGG | Male-baised eQTL |
| rs12567098 | chr1:227839542:C:T | - | 0.0402134583381815 | 0.0195631518585095 | LGG | Male-baised eQTL |
| rs12565154 | chr1:227839609:G:A | - | 0.0402134583381815 | 0.0195631518585095 | LGG | Male-baised eQTL |
| rs16848158 | chr1:227839863:T:C | - | 0.0402134583381815 | 0.0195631518585095 | LGG | Male-baised eQTL |
| rs34778535 | chr1:225161491:C:A | - | 0.034356091156755 | 0.0236826940750036 | LGG | Male-baised eQTL |
| rs10916435 | chr1:229150902:C:G | - | 0.0341425010497061 | 0.0237238017997104 | LGG | Male-baised eQTL |
| rs61851479 | chr1:225176967:G:A | - | 0.0329987252087038 | 0.0310403217515708 | LGG | Male-baised eQTL |
| rs80045052 | chr1:225173858:T:C | - | 0.0329791863769847 | 0.031309232350731 | LGG | Male-baised eQTL |
| rs1847906 | chr1:225163942:G:C | - | 0.0329528146776052 | 0.0314685746954396 | LGG | Male-baised eQTL |
| rs12403778 | chr1:225168512:C:A | - | 0.0329528146776052 | 0.0314685746954396 | LGG | Male-baised eQTL |
| rs34436845 | chr1:225177607:G:A | - | 0.0329528146776052 | 0.0314685746954396 | LGG | Male-baised eQTL |
| rs34407424 | chr1:225198363:C:T | - | 0.0329528146776052 | 0.0314685746954396 | LGG | Male-baised eQTL |
| rs61851518 | chr1:225210186:C:T | - | 0.0329528146776052 | 0.0314685746954396 | LGG | Male-baised eQTL |
| rs61851520 | chr1:225210339:C:T | - | 0.0329528146776052 | 0.0314685746954396 | LGG | Male-baised eQTL |
| rs34517951 | chr1:225153152:C:T | - | 0.0329429629263319 | 0.0317538813751027 | LGG | Male-baised eQTL |
| rs1466468 | chr1:225206943:A:T | - | 0.0326095695913643 | 0.0326600415009718 | LGG | Male-baised eQTL |
| rs12740067 | chr1:225154299:G:A | - | 0.0326949556550709 | 0.033045052845029 | LGG | Male-baised eQTL |
| rs7516304 | chr1:220316704:G:A | - | 0.0427464925826964 | 0.0330956865242259 | LGG | Male-baised eQTL |
| rs12754230 | chr1:225204550:C:T | - | 0.0325494194474429 | 0.0332380052902532 | LGG | Male-baised eQTL |
| rs35553993 | chr1:225179286:C:A | - | 0.0326481169048076 | 0.0340409796204397 | LGG | Male-baised eQTL |
| rs1842332 | chr1:225152539:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34468096 | chr1:225154386:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12408302 | chr1:225158491:A:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs1480101 | chr1:225159273:C:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12736406 | chr1:225161587:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34766551 | chr1:225162218:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4653607 | chr1:225163488:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs1847907 | chr1:225163824:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs16844408 | chr1:225165401:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs35181350 | chr1:225165686:C:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12733373 | chr1:225165785:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12758819 | chr1:225165931:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12090119 | chr1:225166454:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs10915791 | chr1:225166715:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12410491 | chr1:225166916:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs55680010 | chr1:225167233:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12754116 | chr1:225167823:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12411172 | chr1:225168625:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12411174 | chr1:225168665:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs6666735 | chr1:225168864:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs150409953 | chr1:225169375:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs116165238 | chr1:225169521:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs149177808 | chr1:225169687:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs35852721 | chr1:225170969:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs143291577 | chr1:225171389:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs115930902 | chr1:225171675:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs75536924 | chr1:225171955:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs148158993 | chr1:225172484:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12073257 | chr1:225172652:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs74505783 | chr1:225173715:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs72748625 | chr1:225173800:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851475 | chr1:225173976:C:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851476 | chr1:225174117:T:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12403292 | chr1:225174374:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs59700867 | chr1:225175832:G:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs59493468 | chr1:225175833:C:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34764920 | chr1:225176238:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs9887975 | chr1:225176270:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851478 | chr1:225176545:C:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs9887766 | chr1:225177984:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34305765 | chr1:225178240:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851481 | chr1:225179578:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4653608 | chr1:225180141:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4653610 | chr1:225180473:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11583479 | chr1:225180532:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11578729 | chr1:225181662:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12068189 | chr1:225181756:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12068193 | chr1:225181778:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs35150136 | chr1:225181979:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34256167 | chr1:225182033:A:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12064555 | chr1:225182133:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11580638 | chr1:225182761:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs35948433 | chr1:225183015:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11585032 | chr1:225183161:C:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851487 | chr1:225185370:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12077966 | chr1:225186234:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851489 | chr1:225186837:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12729289 | chr1:225187766:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs57650955 | chr1:225188146:A:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs55738724 | chr1:225188155:G:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34304596 | chr1:225188454:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4623662 | chr1:225190666:G:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4319288 | chr1:225190704:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4653413 | chr1:225191539:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs10799296 | chr1:225193832:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11583802 | chr1:225193948:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11582482 | chr1:225194216:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs7541259 | chr1:225196003:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34524645 | chr1:225196412:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4653614 | chr1:225197045:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs35161243 | chr1:225197478:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34051059 | chr1:225197926:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs34248528 | chr1:225198252:G:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs4653616 | chr1:225198967:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs116772638 | chr1:225199993:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11585124 | chr1:225201379:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs10915797 | chr1:225201563:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs10915798 | chr1:225202166:T:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12410126 | chr1:225202531:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12406388 | chr1:225202632:A:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs11584486 | chr1:225203032:T:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12733733 | chr1:225203231:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12740354 | chr1:225204921:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12758681 | chr1:225205619:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12097990 | chr1:225205885:C:T | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12077485 | chr1:225206300:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs1480107 | chr1:225207509:T:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs56280792 | chr1:225208130:G:A | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs61851519 | chr1:225210272:T:C | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs10915802 | chr1:225210756:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs10915803 | chr1:225210918:A:G | - | 0.0325869318276034 | 0.0344963818894946 | LGG | Male-baised eQTL |
| rs12403752 | chr1:225168337:C:T | - | 0.0325643849518017 | 0.0352426501188989 | LGG | Male-baised eQTL |
| rs7536245 | chr1:225154579:A:C | - | 0.0325341665889423 | 0.0354957072987558 | LGG | Male-baised eQTL |
| rs36053633 | chr1:225155716:A:G | - | 0.0325341665889423 | 0.0354957072987558 | LGG | Male-baised eQTL |
| rs55770610 | chr1:225156025:T:C | - | 0.0325341665889423 | 0.0354957072987558 | LGG | Male-baised eQTL |
| rs11582452 | chr1:234516109:C:T | - | 0.039441384574474 | 0.0369605598155398 | LGG | Male-baised eQTL |
| rs9793832 | chr1:229151372:G:A | - | 0.032316018681847 | 0.0381231280488491 | LGG | Male-baised eQTL |
| rs2035302 | chr1:225165913:G:A | - | 0.0321174158944996 | 0.0396488991587064 | LGG | Male-baised eQTL |
| rs9726077 | chr1:229136743:G:A | - | 0.0347716875637734 | 0.0443977106153861 | LGG | Male-baised eQTL |
| rs9724867 | chr1:229140969:C:G | - | 0.0347716875637734 | 0.0443977106153861 | LGG | Male-baised eQTL |
| rs9725734 | chr1:232349233:A:G | - | 0.0382373554340218 | 0.0450565819725578 | LGG | Male-baised eQTL |
| rs61824031 | chr1:232341950:G:A | - | 0.0381836321024758 | 0.0465517117951876 | LGG | Male-baised eQTL |
| rs11118396 | chr1:219721510:A:G | - | 0.0337675700849114 | 0.0484467174842322 | LGG | Male-baised eQTL |
| rs4011943 | chr1:219754519:C:T | - | 0.0489714312943151 | 0.0364099259314108 | KIRC | Male-baised eQTL |
| rs10779382 | chr1:219757296:T:G | - | 0.0483677530021426 | 0.0364227389924888 | KIRC | Male-baised eQTL |
| rs6662037 | chr1:219757835:T:C | - | 0.0483677530021426 | 0.0364227389924888 | KIRC | Male-baised eQTL |
| rs61824824 | chr1:230464961:G:A | - | 0.061898333505499 | 0.00670778267976885 | BLCA | Male-baised eQTL |
| rs112179983 | chr1:221356403:G:A | - | 0.0499158187119357 | 0.0116798320016825 | BLCA | Male-baised eQTL |
| rs12121936 | chr1:221374731:A:G | - | 0.0521557835041025 | 0.0138438046193382 | BLCA | Male-baised eQTL |
| rs7512505 | chr1:224998449:C:T | - | 0.05385513380529 | 0.0152377298717674 | BLCA | Male-baised eQTL |
| rs1110204 | chr1:224913645:G:T | - | 0.0499860326126406 | 0.0205463680473203 | BLCA | Male-baised eQTL |
| rs76778398 | chr1:224889045:T:C | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs79726643 | chr1:224889622:C:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs140839185 | chr1:224891167:T:C | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs112450372 | chr1:224895338:C:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs77601427 | chr1:224896879:G:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs79427096 | chr1:224897166:C:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs75583666 | chr1:224906948:G:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs76324917 | chr1:224908054:G:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs74228664 | chr1:224909238:T:C | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs113164052 | chr1:224909723:G:A | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs78740218 | chr1:224909846:C:T | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs111484883 | chr1:224915639:A:G | - | 0.0497433059032652 | 0.0215184681810092 | BLCA | Male-baised eQTL |
| rs74228665 | chr1:224910862:C:T | - | 0.0497248557199428 | 0.0217057124177926 | BLCA | Male-baised eQTL |
| rs77392783 | chr1:224951574:C:T | - | 0.0506410806118054 | 0.022848536026115 | BLCA | Male-baised eQTL |
| rs74326665 | chr1:224930087:T:C | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs78999641 | chr1:224930102:C:T | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs74228668 | chr1:224930403:G:A | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs78493197 | chr1:224932520:A:G | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs79251588 | chr1:224935739:T:A | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs112711608 | chr1:224945322:G:A | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs77496799 | chr1:224949204:T:C | - | 0.0504511383209465 | 0.023872378937242 | BLCA | Male-baised eQTL |
| rs78483898 | chr1:224923910:C:T | - | 0.0498609978679226 | 0.0240287078755923 | BLCA | Male-baised eQTL |
| rs76273985 | chr1:224920905:G:A | - | 0.0504004435333334 | 0.024105923820206 | BLCA | Male-baised eQTL |
| rs77963990 | chr1:224921133:C:T | - | 0.0504004435333334 | 0.024105923820206 | BLCA | Male-baised eQTL |
| rs75332115 | chr1:224922191:G:C | - | 0.0504004435333334 | 0.024105923820206 | BLCA | Male-baised eQTL |
| rs79602683 | chr1:224922493:G:C | - | 0.0504004435333334 | 0.024105923820206 | BLCA | Male-baised eQTL |
| rs75297900 | chr1:224928854:A:G | - | 0.0504004435333334 | 0.024105923820206 | BLCA | Male-baised eQTL |
| rs186268880 | chr1:225124003:T:A | - | 0.0507457953111915 | 0.0254774447236752 | BLCA | Male-baised eQTL |
| rs190342028 | chr1:225124004:C:T | - | 0.0507457953111915 | 0.0254774447236752 | BLCA | Male-baised eQTL |
| rs41267347 | chr1:224955008:A:T | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs74589226 | chr1:224962323:T:C | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs77345779 | chr1:224969295:G:A | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs74699857 | chr1:224973268:A:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs72470459 | chr1:224974175:A:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs75625634 | chr1:224976448:C:T | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs111669697 | chr1:224978109:C:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs78820667 | chr1:224979733:C:T | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs76032339 | chr1:224983461:A:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs75254122 | chr1:224993512:C:A | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs78638349 | chr1:224994422:A:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs80016617 | chr1:225001436:G:A | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs79257893 | chr1:225003562:G:T | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs78139584 | chr1:225004178:C:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs111324438 | chr1:225008070:C:T | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs77414544 | chr1:225008896:C:T | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs111862721 | chr1:225012408:G:A | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs75044318 | chr1:225014734:A:G | - | 0.0486243396401514 | 0.031699181715882 | BLCA | Male-baised eQTL |
| rs113684846 | chr1:225079766:C:T | - | 0.0491029192338414 | 0.0324733259160464 | BLCA | Male-baised eQTL |
| rs113766704 | chr1:225069790:C:T | - | 0.0489471641990149 | 0.0335939150477044 | BLCA | Male-baised eQTL |
| rs79661750 | chr1:225015423:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs72470460 | chr1:225015966:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76393468 | chr1:225016791:G:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76243018 | chr1:225021743:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs77066564 | chr1:225021827:C:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs77680089 | chr1:225022380:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs75568712 | chr1:225023720:T:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs74799385 | chr1:225024092:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79494650 | chr1:225029206:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs78820939 | chr1:225029569:G:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs75691563 | chr1:225031074:A:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs113323495 | chr1:225033731:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76072081 | chr1:225035451:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs111633780 | chr1:225040196:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs112144323 | chr1:225043202:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76646941 | chr1:225045077:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79624101 | chr1:225046389:T:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79257940 | chr1:225051120:C:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs140027400 | chr1:225056306:A:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs146406213 | chr1:225056541:C:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs138345197 | chr1:225059110:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76209482 | chr1:225064159:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76152480 | chr1:225065232:T:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs112138802 | chr1:225067993:T:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79980731 | chr1:225073124:G:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs111356544 | chr1:225074219:T:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76325262 | chr1:225085105:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs75627582 | chr1:225086098:C:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs78045355 | chr1:225087664:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs111353306 | chr1:225089440:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79881018 | chr1:225092720:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs74592028 | chr1:225094738:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs77125869 | chr1:225095958:T:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs186655426 | chr1:225098215:C:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs77726744 | chr1:225098319:C:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76045707 | chr1:225101315:G:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs111304225 | chr1:225102292:G:C | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs142371261 | chr1:225106395:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79244146 | chr1:225112054:C:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs112170648 | chr1:225112793:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs78714220 | chr1:225113161:T:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs75509747 | chr1:225116209:G:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs78378295 | chr1:225120670:T:A | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs79298703 | chr1:225121065:C:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs76946626 | chr1:225123610:C:T | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs375213673 | chr1:225129820:A:G | - | 0.0487540437410438 | 0.0347944759451899 | BLCA | Male-baised eQTL |
| rs78134977 | chr1:225150941:C:A | - | 0.048741486009129 | 0.0349470087520482 | BLCA | Male-baised eQTL |
| rs189815590 | chr1:225103149:A:C | - | 0.048713625516618 | 0.035157744060053 | BLCA | Male-baised eQTL |
| rs113723992 | chr1:224924633:G:A | - | 0.0458052681148887 | 0.0442685830558332 | BLCA | Male-baised eQTL |
| rs28359726 | chr1:230795030:A:C | - | 0.127247858504566 | 0.0340823141824033 | LUAD | Male-baised eQTL |
| rs7547759 | chr1:218466247:G:T | - | 0.0861421316604851 | 0.0344061931064356 | COAD | Male-baised eQTL |
| rs7526672 | chr1:218472531:T:G | - | 0.0861421316604851 | 0.0344061931064356 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg24937136 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.226494323150009 | |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg18590995 | |
| Position to Gene: gene,exon | |
| Male Effect: - | |
| Female Effect: -0.455989846727302 | |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg23712594 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.274169040259974 | |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg24937136 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.205559457586866 | |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg18590995 | |
| Position to Gene: gene,exon | |
| Male Effect: -0.45070711155785 | |
| Female Effect: - | |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg23712594 | |
| Position to Gene: gene | |
| Male Effect: -0.45070711155785 | |
| Female Effect: - | |
 | Gene ID: ENSG00000143799 |
| CpG Site: cg24937136 | |
| Position to Gene: gene | |
| Male Effect: -0.141031037084697 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg18590995 | chr1:226370795 | gene,exon | -0.45070711155785 | 2.80574128721653e-43 | -0.7058480543071727 | 2.743501885071689e-47 | BLCA |
| cg23712594 | chr1:226404189 | gene | -0.45070711155785 | 2.80574128721653e-43 | -0.7058480543071727 | 2.743501885071689e-47 | BLCA |
| cg24937136 | chr1:226405645 | gene | -0.141031037084697 | 7.82076456694021e-13 | -0.4395948206556245 | 7.647664478473024e-16 | BLCA |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg24937136 | chr1:226405645 | gene | -0.226494323150009 | 3.01513417395336e-06 | -0.3613301201146502 | 2.7874382137134943e-09 | LUAD |
| cg18590995 | chr1:226370795 | gene,exon | -0.455989846727302 | 8.74781799787215e-26 | -0.8172894921971501 | 1.5257075632819238e-29 | STAD |
| cg23712594 | chr1:226404189 | gene | -0.274169040259974 | 9.53675137833028e-15 | -0.6993526290217706 | 2.508668433355714e-18 | STAD |
| cg24937136 | chr1:226405645 | gene | -0.205559457586866 | 1.14173273938937e-06 | -0.5173432187812811 | 1.992199379710224e-09 | STAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of PARP1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000143799 | PARP1 | C0002170 | Alopecia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0002871 | Anemia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0004096 | Asthma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0004153 | Atherosclerosis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0007786 | Brain Ischemia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0009402 | Colorectal Carcinoma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0011603 | Dermatitis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0014518 | Toxic Epidermal Necrolysis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0015697 | Arterial Fatty Streak | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0019158 | Hepatitis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0020796 | Profound Mental Retardation | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0021368 | Inflammation | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0022658 | Kidney Diseases | 2 | CTD_human |
| ENSG00000143799 | PARP1 | C0022821 | Kyphosis deformity of spine | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0025202 | melanoma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0025363 | Mental Retardation, Psychosocial | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0026764 | Multiple Myeloma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0028754 | Obesity | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0032285 | Pneumonia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0032300 | Lobar Pneumonia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0033141 | Cardiomyopathies, Primary | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0034069 | Pulmonary Fibrosis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0036529 | Myocardial Diseases, Secondary | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0038325 | Stevens-Johnson Syndrome | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0042842 | Vitamin A Deficiency | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0086873 | Pseudopelade | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0162311 | Androgenetic Alopecia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0242422 | Parkinsonian Disorders | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0242423 | Ramsay Hunt Paralysis Syndrome | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0263477 | Female pattern alopecia (disorder) | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0264956 | Atheroma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0752097 | Autosomal Dominant Juvenile Parkinson Disease | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0752098 | Autosomal Dominant Parkinsonism | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0752100 | Autosomal Recessive Parkinsonism | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0752101 | Parkinsonism, Experimental | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0752104 | Familial Juvenile Parkinsonism | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0752105 | Parkinsonism, Juvenile | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0878544 | Cardiomyopathies | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0887898 | Experimental Lung Inflammation | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0917798 | Cerebral Ischemia | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C0917816 | Mental deficiency | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C1274933 | Drug-Induced Stevens Johnson Syndrome | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C1563937 | Atherogenesis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C1868675 | PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C2931673 | Ceroid lipofuscinosis, neuronal 1, infantile | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C2936350 | Plaque, Atherosclerotic | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C2936351 | Fibroatheroma | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C3658301 | Mycoplasma-Induced Stevens-Johnson Syndrome | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C3658302 | Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C3714636 | Pneumonitis | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C3714756 | Intellectual Disability | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C4083212 | Alopecia, Male Pattern | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
| ENSG00000143799 | PARP1 | C4721507 | Alveolitis, Fibrosing | 1 | CTD_human |
