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Gene: ENSG00000143514 |
Summary for TP53BP2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000143514 | Gene symbol | TP53BP2 |
| Gene name | tumor protein p53 binding protein 2 | |
| HGNC | 12000 | |
| Entrez ID | 7159 | |
| Gene type | protein_coding | |
| Synonyms | TP53BP2|PPP1R13A|ASPP2|53BP2 | |
| UniProtAcc | Q13625 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TP53BP2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for TP53BP2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for TP53BP2 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg02526551 | chr1:223844093 | CGI:chr1:223845383-223846561 | promoter,gene body | 7.27e-01 | 6.10e-01 | 2.85e+00 | 4.38e-03 | 7.39e-03 | 1.18e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRP | cg02526551 | chr1:223844093 | CGI:chr1:223845383-223846561 | promoter,gene body | 6.78e-01 | 8.84e-01 | -2.11e+00 | 3.53e-02 | 3.93e-02 | -2.06e-01 |
Top |
Exon skipping events with PSI in TCGA for TP53BP2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for TP53BP2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| STAD | TP53BP2-005 | chr1_223790742_- | 8.13e-01 | 6.53e-01 | 1.99e+00 | 4.63e-02 | 4.96e-02 | 1.60e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for TP53BP2 |
| TFs related to TP53BP2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| MESO | ZNF418 | TP53BP2 | 2.43e+00 | 2.54e-03 | 4.10e+00 | 9.85e-01 | Female-biased |
| PAAD | BARX1 | TP53BP2 | 4.09e+00 | 9.85e-01 | 2.93e+00 | 1.77e-03 | Male-biased |
| PAAD | BARX2 | TP53BP2 | 4.45e+00 | 9.92e-01 | 3.17e+00 | 1.00e-03 | Male-biased |
| PAAD | DMRT2 | TP53BP2 | 4.56e+00 | 9.93e-01 | 3.31e+00 | 1.18e-03 | Male-biased |
| PAAD | DMRT3 | TP53BP2 | 4.47e+00 | 9.91e-01 | 3.31e+00 | 1.84e-03 | Male-biased |
| PAAD | DMRTA1 | TP53BP2 | 4.45e+00 | 9.92e-01 | 3.19e+00 | 1.06e-03 | Male-biased |
| PAAD | DMRTA2 | TP53BP2 | 4.50e+00 | 9.92e-01 | 3.31e+00 | 1.62e-03 | Male-biased |
| PAAD | FOXD3 | TP53BP2 | 3.99e+00 | 9.85e-01 | 2.43e+00 | 2.16e-04 | Male-biased |
| PAAD | FOXE1 | TP53BP2 | 3.84e+00 | 9.81e-01 | 2.57e+00 | 9.51e-04 | Male-biased |
| PAAD | FOXO1 | TP53BP2 | 4.04e+00 | 9.83e-01 | 3.01e+00 | 3.38e-03 | Male-biased |
| PAAD | FOXP1 | TP53BP2 | 4.18e+00 | 9.84e-01 | 3.21e+00 | 4.89e-03 | Male-biased |
| PAAD | HOXB7 | TP53BP2 | 4.00e+00 | 9.83e-01 | 2.91e+00 | 2.65e-03 | Male-biased |
| PAAD | HOXB8 | TP53BP2 | 4.25e+00 | 9.85e-01 | 3.28e+00 | 4.85e-03 | Male-biased |
| PAAD | MEIS1 | TP53BP2 | 4.24e+00 | 9.85e-01 | 3.28e+00 | 5.11e-03 | Male-biased |
| PAAD | MYNN | TP53BP2 | 4.03e+00 | 9.85e-01 | 2.81e+00 | 1.25e-03 | Male-biased |
| PAAD | NKX3-1 | TP53BP2 | 4.32e+00 | 9.91e-01 | 2.89e+00 | 4.41e-04 | Male-biased |
| PAAD | POU1F1 | TP53BP2 | 4.23e+00 | 9.84e-01 | 3.28e+00 | 5.58e-03 | Male-biased |
| PAAD | POU4F3 | TP53BP2 | 4.11e+00 | 9.86e-01 | 2.93e+00 | 1.66e-03 | Male-biased |
| PAAD | POU5F1B | TP53BP2 | 4.18e+00 | 9.87e-01 | 3.00e+00 | 1.67e-03 | Male-biased |
| PAAD | SOX10 | TP53BP2 | 4.02e+00 | 9.84e-01 | 2.87e+00 | 1.88e-03 | Male-biased |
| PAAD | SOX8 | TP53BP2 | 4.01e+00 | 9.84e-01 | 2.86e+00 | 1.88e-03 | Male-biased |
| PAAD | SOX9 | TP53BP2 | 4.08e+00 | 9.86e-01 | 2.81e+00 | 9.81e-04 | Male-biased |
| PAAD | ZKSCAN2 | TP53BP2 | 4.01e+00 | 9.85e-01 | 2.74e+00 | 9.84e-04 | Male-biased |
| PAAD | ZNF232 | TP53BP2 | 4.46e+00 | 9.87e-01 | 3.51e+00 | 5.45e-03 | Male-biased |
| PAAD | ZNF25 | TP53BP2 | 3.91e+00 | 9.83e-01 | 2.22e+00 | 9.73e-05 | Male-biased |
| PAAD | ZNF250 | TP53BP2 | 3.99e+00 | 9.82e-01 | 2.95e+00 | 3.32e-03 | Male-biased |
| PAAD | ZNF317 | TP53BP2 | 3.94e+00 | 9.81e-01 | 2.86e+00 | 2.80e-03 | Male-biased |
| PAAD | ZNF33B | TP53BP2 | 4.04e+00 | 9.86e-01 | 2.71e+00 | 7.21e-04 | Male-biased |
| PAAD | ZNF418 | TP53BP2 | 4.30e+00 | 9.91e-01 | 2.26e+00 | 1.27e-05 | Male-biased |
| PAAD | ZNF580 | TP53BP2 | 4.32e+00 | 9.90e-01 | 3.00e+00 | 7.95e-04 | Male-biased |
| PAAD | ZNF716 | TP53BP2 | 3.90e+00 | 9.82e-01 | 2.64e+00 | 1.05e-03 | Male-biased |
| PAAD | ZNF879 | TP53BP2 | 3.82e+00 | 9.81e-01 | 2.19e+00 | 1.40e-04 | Male-biased |
| SARC | BARX2 | TP53BP2 | 4.68e+00 | 9.82e-01 | 4.16e+00 | 1.27e-02 | Male-biased |
| SARC | DMRT2 | TP53BP2 | 4.80e+00 | 9.84e-01 | 4.26e+00 | 1.15e-02 | Male-biased |
| SARC | DMRT3 | TP53BP2 | 4.71e+00 | 9.84e-01 | 4.17e+00 | 1.11e-02 | Male-biased |
| SARC | DMRTA2 | TP53BP2 | 4.71e+00 | 9.80e-01 | 4.20e+00 | 1.46e-02 | Male-biased |
| SARC | FOXD3 | TP53BP2 | 4.25e+00 | 9.86e-01 | 3.51e+00 | 3.39e-03 | Male-biased |
| SARC | FOXO1 | TP53BP2 | 4.40e+00 | 9.86e-01 | 3.75e+00 | 5.86e-03 | Male-biased |
| SARC | MEIS1 | TP53BP2 | 4.50e+00 | 9.84e-01 | 3.92e+00 | 8.93e-03 | Male-biased |
| SARC | NKX3-1 | TP53BP2 | 4.59e+00 | 9.83e-01 | 4.05e+00 | 1.11e-02 | Male-biased |
| SARC | POU4F3 | TP53BP2 | 4.51e+00 | 9.90e-01 | 3.77e+00 | 3.26e-03 | Male-biased |
| SARC | POU5F1B | TP53BP2 | 4.39e+00 | 9.83e-01 | 3.79e+00 | 7.94e-03 | Male-biased |
| SARC | SOX9 | TP53BP2 | 4.33e+00 | 9.84e-01 | 3.71e+00 | 6.79e-03 | Male-biased |
| SARC | TLX3 | TP53BP2 | 5.44e+00 | 9.90e-01 | 4.84e+00 | 7.95e-03 | Male-biased |
| SARC | ZKSCAN2 | TP53BP2 | 4.25e+00 | 9.81e-01 | 3.66e+00 | 8.06e-03 | Male-biased |
| SARC | ZNF232 | TP53BP2 | 4.64e+00 | 9.85e-01 | 4.07e+00 | 9.41e-03 | Male-biased |
| SARC | ZNF25 | TP53BP2 | 4.25e+00 | 9.81e-01 | 3.67e+00 | 8.34e-03 | Male-biased |
| SARC | ZNF33B | TP53BP2 | 4.29e+00 | 9.86e-01 | 3.59e+00 | 4.17e-03 | Male-biased |
| SARC | ZNF418 | TP53BP2 | 4.35e+00 | 9.83e-01 | 3.74e+00 | 7.49e-03 | Male-biased |
| TP53BP2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for TP53BP2 |
| RBPs related to ES in TP53BP2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | YBX2 | exon_skip_37320 | 1.47e+01 | 9.94e-01 | 1.42e+01 | 5.98e-03 | Male-biased |
| UVM | YBX2 | exon_skip_37320 | 1.42e+01 | 1.00e+00 | 1.36e+01 | 2.16e-04 | Male-biased |
| UVM | ZFP36 | exon_skip_37318 | 7.36e+00 | 9.32e-03 | 7.67e+00 | 9.81e-01 | Female-biased |
| COAD | PPRC1 | exon_skip_37318 | 1.28e+01 | 9.96e-01 | 1.24e+01 | 3.87e-03 | Male-biased |
| DLBC | YBX2 | exon_skip_37320 | 1.40e+01 | 1.76e-04 | 1.48e+01 | 1.00e+00 | Female-biased |
| KIRP | YBX2 | exon_skip_37320 | 1.39e+01 | 4.08e-03 | 1.44e+01 | 9.96e-01 | Female-biased |
| ESCA | YBX2 | exon_skip_37320 | 1.37e+01 | 4.26e-03 | 1.43e+01 | 9.96e-01 | Female-biased |
| MESO | YBX2 | exon_skip_37320 | 1.36e+01 | 1.42e-04 | 1.44e+01 | 1.00e+00 | Female-biased |
| GBM | YBX2 | exon_skip_37320 | 1.37e+01 | 6.97e-04 | 1.43e+01 | 9.99e-01 | Female-biased |
| KIRC | YB-1 | exon_skip_37329 | 7.26e+00 | 5.93e-03 | 7.62e+00 | 9.84e-01 | Female-biased |
| KICH | PPRC1 | exon_skip_37318 | 1.25e+01 | 9.97e-01 | 1.20e+01 | 2.53e-03 | Male-biased |
| BLCA | ZFP36 | exon_skip_37318 | 7.05e+00 | 7.84e-03 | 7.43e+00 | 9.81e-01 | Female-biased |
| HNSC | FXR2 | exon_skip_37324 | 7.08e+00 | 9.84e-01 | 6.62e+00 | 3.20e-03 | Male-biased |
| HNSC | YBX2 | exon_skip_37320 | 1.39e+01 | 3.72e-03 | 1.43e+01 | 9.96e-01 | Female-biased |
| SARC | YBX2 | exon_skip_37320 | 1.38e+01 | 3.39e-03 | 1.43e+01 | 9.96e-01 | Female-biased |
| TP53BP2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2030078 | chr1:219968291:C:G | - | 0.103836745413043 | 0.0225842590876371 | BLCA | Female-baised eQTL |
| rs12409750 | chr1:219965176:T:G | - | 0.103868490754901 | 0.0243451573423825 | BLCA | Female-baised eQTL |
| rs2027504 | chr1:219967372:T:C | - | 0.102123201821132 | 0.0308361998376095 | BLCA | Female-baised eQTL |
| rs11118477 | chr1:219967727:T:C | - | 0.102123201821132 | 0.0308361998376095 | BLCA | Female-baised eQTL |
| rs2030079 | chr1:219968191:A:G | - | 0.102086841704465 | 0.0309594073155868 | BLCA | Female-baised eQTL |
| rs28473426 | chr1:219956483:A:C | - | 0.100889992428584 | 0.0327426196809574 | BLCA | Female-baised eQTL |
| rs4385715 | chr1:219963214:A:C | - | 0.100779754928962 | 0.0331890992897367 | BLCA | Female-baised eQTL |
| rs11811258 | chr1:219964391:A:G | - | 0.100779754928962 | 0.0331890992897367 | BLCA | Female-baised eQTL |
| rs1982986 | chr1:219972242:C:T | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs1982984 | chr1:219972313:C:T | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs34309222 | chr1:219972604:T:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs949866 | chr1:219973001:A:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs10779391 | chr1:219974003:G:A | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs12045445 | chr1:219974311:G:A | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs12126940 | chr1:219974482:C:A | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs7521388 | chr1:219974748:C:T | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs7535650 | chr1:219974911:T:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs7521682 | chr1:219975010:C:T | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs7535767 | chr1:219975044:T:A | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs7535773 | chr1:219975058:T:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs1846255 | chr1:219975447:T:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs1846254 | chr1:219975458:T:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs1498394 | chr1:219975837:T:C | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs201242785 | chr1:219975845:T:A | - | 0.102238008835769 | 0.0368409712837351 | BLCA | Female-baised eQTL |
| rs12049352 | chr1:219970992:A:C | - | 0.100983229661596 | 0.038986361256287 | BLCA | Female-baised eQTL |
| rs1061248 | chr1:219968681:C:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs1061242 | chr1:219968728:C:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs2270712 | chr1:219969270:C:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs3816993 | chr1:219969329:T:C | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs12098052 | chr1:219969600:T:C | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs1874814 | chr1:219969884:T:A | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs1874813 | chr1:219969967:G:A | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs1874812 | chr1:219970141:C:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs12726890 | chr1:219970345:T:C | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs12032866 | chr1:219970818:C:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs12032898 | chr1:219970881:C:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs4536003 | chr1:219971640:A:T | - | 0.100963214527814 | 0.0390833125723766 | BLCA | Female-baised eQTL |
| rs7536968 | chr1:219976532:A:G | - | 0.101184218164012 | 0.0415776730571969 | BLCA | Female-baised eQTL |
| rs7527659 | chr1:219976664:C:G | - | 0.101184218164012 | 0.0415776730571969 | BLCA | Female-baised eQTL |
| rs7527749 | chr1:219976737:C:G | - | 0.101184218164012 | 0.0415776730571969 | BLCA | Female-baised eQTL |
| rs2270710 | chr1:219978350:A:G | - | 0.101180932357576 | 0.0415986018225665 | BLCA | Female-baised eQTL |
| rs11118474 | chr1:219962334:A:G | - | 0.099692488095689 | 0.0425987198602291 | BLCA | Female-baised eQTL |
| rs11118476 | chr1:219966396:C:T | - | 0.099692488095689 | 0.0425987198602291 | BLCA | Female-baised eQTL |
| rs10746394 | chr1:219963899:A:G | - | 0.099179318344596 | 0.0432880443711437 | BLCA | Female-baised eQTL |
| rs7553236 | chr1:219978302:G:A | - | 0.0996947135263452 | 0.045015762806379 | BLCA | Female-baised eQTL |
| rs3816994 | chr1:219968509:T:G | - | 0.10015368519193 | 0.0472897130452921 | BLCA | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs265121 | chr1:217423360:G:T | - | 0.0677080684365739 | 0.0465754302646819 | BLCA | Male-baised eQTL |
| rs4536002 | chr1:219729660:A:G | - | -0.0874711605740094 | 0.031988233566539 | LUAD | Male-baised eQTL |
| rs1766403 | chr1:219749092:C:T | - | -0.0827660157523371 | 0.0375565333734582 | LUAD | Male-baised eQTL |
| rs9729514 | chr1:219727713:A:G | - | -0.0832593665298908 | 0.0416858361011955 | LUAD | Male-baised eQTL |
| rs10746391 | chr1:219735295:A:C | - | -0.0852239094230513 | 0.0431719546522252 | LUAD | Male-baised eQTL |
| rs6669717 | chr1:219739427:C:T | - | -0.0852239094230513 | 0.0431719546522252 | LUAD | Male-baised eQTL |
| rs2795467 | chr1:232794311:A:G | - | 0.0584746093315113 | 0.00608412560345466 | COAD | Male-baised eQTL |
| rs2814509 | chr1:232782860:T:C | - | 0.0597586232789166 | 0.00775772395177272 | COAD | Male-baised eQTL |
| rs4846288 | chr1:219234794:T:C | - | -0.0591146459022227 | 0.0196242530965151 | COAD | Male-baised eQTL |
| rs869543 | chr1:219242937:A:C | - | -0.0576743897548847 | 0.0227203689608473 | COAD | Male-baised eQTL |
| rs4846542 | chr1:219257725:G:A | - | -0.0576743897548847 | 0.0227203689608473 | COAD | Male-baised eQTL |
| rs2105465 | chr1:219262143:C:G | - | -0.0576743897548847 | 0.0227203689608473 | COAD | Male-baised eQTL |
| rs17049139 | chr1:219198816:G:A | - | 0.0599942842895637 | 0.0240165046067922 | COAD | Male-baised eQTL |
| rs12125703 | chr1:219205370:A:C | - | 0.0599942842895637 | 0.0240165046067922 | COAD | Male-baised eQTL |
| rs61824005 | chr1:223777629:C:T | - | 0.0760733661280658 | 0.0262844900195768 | COAD | Male-baised eQTL |
| rs12137855 | chr1:219275036:C:T | - | 0.0610166370389432 | 0.0264995829021246 | COAD | Male-baised eQTL |
| rs61836091 | chr1:219275396:G:A | - | 0.0610166370389432 | 0.0264995829021246 | COAD | Male-baised eQTL |
| rs12088254 | chr1:223779649:C:T | - | 0.0726093941560293 | 0.0286359025981567 | COAD | Male-baised eQTL |
| rs10863436 | chr1:219194709:A:G | - | -0.0545590412133893 | 0.032303905282355 | COAD | Male-baised eQTL |
| rs4846537 | chr1:219204067:G:T | - | -0.0557131617782171 | 0.0324436122956886 | COAD | Male-baised eQTL |
| rs113720073 | chr1:223777989:T:C | - | 0.0666070801385907 | 0.0442684156944995 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TP53BP2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000143514 | TP53BP2 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| ENSG00000143514 | TP53BP2 | C0027626 | Neoplasm Invasiveness | 1 | CTD_human |
| ENSG00000143514 | TP53BP2 | C0206692 | Carcinoma, Lobular | 1 | CTD_human |
| ENSG00000143514 | TP53BP2 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| ENSG00000143514 | TP53BP2 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| ENSG00000143514 | TP53BP2 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| ENSG00000143514 | TP53BP2 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
