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Gene: ENSG00000140553 |
Summary for UNC45A |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000140553 | Gene symbol | UNC45A |
| Gene name | unc-45 myosin chaperone A | |
| HGNC | 30594 | |
| Entrez ID | 55898 | |
| Gene type | protein_coding | |
| Synonyms | UNC45A|SMAP-1|GC-UNC45 | |
| UniProtAcc | Q9H3U1 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for UNC45A |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for UNC45A |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for UNC45A |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| PCPG | cg08939371 | chr15:90929829 | CGI:chr15:90930084-90930362 | promoter | 3.69e-01 | 2.61e-01 | 2.58e+00 | 9.82e-03 | 2.28e-02 | 1.08e-01 |
| ACC | cg20750528 | chr15:90931226 | CGI:chr15:90930084-90930362 | promoter,exon,gene body | 5.62e-01 | 6.83e-01 | -2.50e+00 | 1.24e-02 | 2.85e-02 | -1.20e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg05878630 | chr15:90931659 | CGI:chr15:90932396-90932696 | promoter,gene body | 6.43e-01 | 8.22e-01 | -3.94e+00 | 8.01e-05 | 1.68e-04 | -1.79e-01 |
| LUSC | cg05878630 | chr15:90931659 | CGI:chr15:90932396-90932696 | promoter,gene body | 3.88e-01 | 6.20e-01 | -3.22e+00 | 1.30e-03 | 3.09e-03 | -2.32e-01 |
| BLCA | cg08939371 | chr15:90929829 | CGI:chr15:90930084-90930362 | promoter | 1.07e-01 | 2.88e-01 | -4.39e+00 | 1.13e-05 | 1.02e-04 | -1.81e-01 |
| BLCA | cg18724928 | chr15:90929861 | CGI:chr15:90930084-90930362 | promoter | 8.67e-02 | 1.97e-01 | -4.29e+00 | 1.76e-05 | 1.29e-04 | -1.10e-01 |
| BLCA | cg18472881 | chr15:90929873 | CGI:chr15:90930084-90930362 | promoter | 1.08e-01 | 2.49e-01 | -4.26e+00 | 2.08e-05 | 1.42e-04 | -1.41e-01 |
| BLCA | cg08551047 | chr15:90930339 | CGI:chr15:90930084-90930362 | promoter,gene body | 1.58e-01 | 2.91e-01 | -3.72e+00 | 1.99e-04 | 6.61e-04 | -1.33e-01 |
| BLCA | cg20750528 | chr15:90931226 | CGI:chr15:90930084-90930362 | promoter,exon,gene body | 6.28e-01 | 7.84e-01 | -2.99e+00 | 2.76e-03 | 5.07e-03 | -1.56e-01 |
| BLCA | cg05878630 | chr15:90931659 | CGI:chr15:90932396-90932696 | promoter,gene body | 3.72e-01 | 7.79e-01 | -4.45e+00 | 8.44e-06 | 8.84e-05 | -4.07e-01 |
| ESCA | cg08551047 | chr15:90930339 | CGI:chr15:90930084-90930362 | promoter,gene body | 1.43e-01 | 2.72e-01 | -2.19e+00 | 2.82e-02 | 4.32e-02 | -1.29e-01 |
| CHOL | cg05878630 | chr15:90931659 | CGI:chr15:90932396-90932696 | promoter,gene body | 3.65e-01 | 7.52e-01 | -2.88e+00 | 4.04e-03 | 1.47e-02 | -3.87e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg05878630 | chr15:90931659 | CGI:chr15:90932396-90932696 | promoter,gene body | 3.08e-01 | 5.19e-01 | -8.80e+00 | 1.40e-18 | 6.74e-18 | -2.11e-01 |
| KIRC | cg08939371 | chr15:90929829 | CGI:chr15:90930084-90930362 | promoter | 8.98e-02 | 2.03e-01 | -3.53e+00 | 4.19e-04 | 3.23e-03 | -1.14e-01 |
| KIRC | cg18724928 | chr15:90929861 | CGI:chr15:90930084-90930362 | promoter | 9.57e-02 | 2.10e-01 | -3.21e+00 | 1.33e-03 | 5.18e-03 | -1.14e-01 |
| KIRC | cg18472881 | chr15:90929873 | CGI:chr15:90930084-90930362 | promoter | 1.25e-01 | 2.33e-01 | -3.21e+00 | 1.33e-03 | 5.18e-03 | -1.09e-01 |
Top |
Exon skipping events with PSI in TCGA for UNC45A |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for UNC45A |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for UNC45A |
| TFs related to UNC45A. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | NHLH1 | UNC45A | 3.18e+00 | 6.97e-03 | 4.51e+00 | 9.83e-01 | Female-biased |
| BRCA | NR1H4 | UNC45A | 3.17e+00 | 4.91e-03 | 4.60e+00 | 9.87e-01 | Female-biased |
| BRCA | PLAG1 | UNC45A | 3.16e+00 | 5.77e-03 | 4.54e+00 | 9.85e-01 | Female-biased |
| BRCA | SNAI1 | UNC45A | 3.20e+00 | 7.49e-03 | 4.50e+00 | 9.82e-01 | Female-biased |
| BRCA | TCF3 | UNC45A | 3.20e+00 | 5.39e-03 | 4.61e+00 | 9.86e-01 | Female-biased |
| BRCA | TFAP2A | UNC45A | 3.36e+00 | 9.91e-03 | 4.57e+00 | 9.81e-01 | Female-biased |
| BRCA | TFAP2B | UNC45A | 3.31e+00 | 8.90e-03 | 4.56e+00 | 9.82e-01 | Female-biased |
| BRCA | TFAP2C | UNC45A | 3.31e+00 | 1.00e-02 | 4.52e+00 | 9.80e-01 | Female-biased |
| BRCA | ZFX | UNC45A | 3.24e+00 | 5.57e-03 | 4.64e+00 | 9.87e-01 | Female-biased |
| BRCA | ZIC2 | UNC45A | 3.08e+00 | 4.21e-03 | 4.56e+00 | 9.87e-01 | Female-biased |
| BRCA | ZNF101 | UNC45A | 3.21e+00 | 6.81e-03 | 4.54e+00 | 9.84e-01 | Female-biased |
| BRCA | ZNF141 | UNC45A | 3.34e+00 | 6.70e-03 | 4.68e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF320 | UNC45A | 2.95e+00 | 5.48e-03 | 4.35e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF331 | UNC45A | 3.19e+00 | 6.60e-03 | 4.53e+00 | 9.84e-01 | Female-biased |
| BRCA | ZNF415 | UNC45A | 3.11e+00 | 7.77e-03 | 4.40e+00 | 9.80e-01 | Female-biased |
| BRCA | ZNF431 | UNC45A | 3.18e+00 | 8.62e-03 | 4.44e+00 | 9.80e-01 | Female-biased |
| BRCA | ZNF454 | UNC45A | 3.21e+00 | 6.37e-03 | 4.56e+00 | 9.85e-01 | Female-biased |
| BRCA | ZNF692 | UNC45A | 3.35e+00 | 5.95e-03 | 4.73e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF891 | UNC45A | 3.16e+00 | 6.74e-03 | 4.50e+00 | 9.83e-01 | Female-biased |
| PAAD | GABPA | UNC45A | 2.61e+00 | 8.97e-04 | 3.86e+00 | 9.83e-01 | Female-biased |
| UNC45A related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for UNC45A |
| RBPs related to ES in UNC45A. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | HNRNPH2 | exon_skip_125055 | 6.00e+00 | 1.99e-04 | 6.81e+00 | 9.85e-01 | Female-biased |
| ACC | SAMD4A | exon_skip_125051 | 7.32e+00 | 9.85e-01 | 6.70e+00 | 2.52e-03 | Male-biased |
| COAD | SAMD4A | exon_skip_125051 | 6.76e+00 | 1.83e-03 | 7.26e+00 | 9.86e-01 | Female-biased |
| DLBC | SAMD4A | exon_skip_125051 | 7.03e+00 | 9.85e-01 | 6.45e+00 | 1.06e-03 | Male-biased |
| DLBC | ZC3H10 | exon_skip_125051 | 7.69e+00 | 9.86e-01 | 7.27e+00 | 4.17e-03 | Male-biased |
| CHOL | G3BP2 | exon_skip_125063 | 9.37e+00 | 9.82e-01 | 9.00e+00 | 1.42e-02 | Male-biased |
| KIRP | ZC3H10 | exon_skip_125051 | 7.56e+00 | 9.86e-01 | 7.13e+00 | 3.41e-03 | Male-biased |
| BRCA | SAMD4A | exon_skip_125051 | 6.42e+00 | 2.10e-03 | 7.55e+00 | 9.88e-01 | Female-biased |
| BRCA | ZC3H10 | exon_skip_125051 | 7.27e+00 | 4.35e-03 | 8.15e+00 | 9.88e-01 | Female-biased |
| READ | SAMD4A | exon_skip_125051 | 6.50e+00 | 2.64e-03 | 6.94e+00 | 9.83e-01 | Female-biased |
| PCPG | G3BP2 | exon_skip_125063 | 8.97e+00 | 4.87e-03 | 9.35e+00 | 9.92e-01 | Female-biased |
| MESO | G3BP2 | exon_skip_125063 | 8.99e+00 | 1.07e-02 | 9.33e+00 | 9.86e-01 | Female-biased |
| KIRC | SAMD4A | exon_skip_125051 | 6.86e+00 | 9.83e-01 | 6.43e+00 | 2.04e-03 | Male-biased |
| SARC | ZC3H10 | exon_skip_125051 | 7.36e+00 | 1.01e-02 | 7.72e+00 | 9.80e-01 | Female-biased |
| UNC45A related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs8025979 | chr15:90234035:G:A | - | 0.167454633342899 | 0.037877352964306 | GBM | Female-baised eQTL |
| rs8027716 | chr15:91243056:G:T | - | 0.138828363714302 | 0.038429073633682 | LUSC | Female-baised eQTL |
| rs719176 | chr15:91242063:G:A | - | 0.141829673457834 | 0.0391230883320367 | LUSC | Female-baised eQTL |
| rs16945429 | chr15:91242728:C:T | - | 0.141829673457834 | 0.0391230883320367 | LUSC | Female-baised eQTL |
| rs11853153 | chr15:91242762:C:T | - | 0.141829673457834 | 0.0391230883320367 | LUSC | Female-baised eQTL |
| rs1586569 | chr15:93376172:C:A | - | 0.136010381874458 | 0.0182688606914074 | STAD | Female-baised eQTL |
| rs11631361 | chr15:95219052:T:C | - | 0.0666699115896689 | 0.00465826721968983 | LUAD | Female-baised eQTL |
| rs28442044 | chr15:95200035:A:G | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs6496095 | chr15:95200397:C:T | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs62019695 | chr15:95201236:C:T | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs60303264 | chr15:95203121:T:A | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs8040473 | chr15:95204332:T:C | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs8024488 | chr15:95205325:A:G | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs8025385 | chr15:95205589:G:A | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs2218461 | chr15:95207112:A:G | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs2197421 | chr15:95207418:G:T | - | 0.0579437180815628 | 0.00588748294464803 | LUAD | Female-baised eQTL |
| rs8037525 | chr15:95191693:T:C | - | 0.0544125396969995 | 0.00669208713221074 | LUAD | Female-baised eQTL |
| rs7163735 | chr15:95196895:G:A | - | 0.0567247288024124 | 0.00706602068087137 | LUAD | Female-baised eQTL |
| rs62019666 | chr15:95178363:A:G | - | 0.0525138145669228 | 0.00780967277906941 | LUAD | Female-baised eQTL |
| rs58316131 | chr15:88980664:A:C | - | 0.0619884125472679 | 0.0080898908747623 | LUAD | Female-baised eQTL |
| rs7181394 | chr15:86171352:C:T | - | 0.0614372462549848 | 0.00997064854848176 | LUAD | Female-baised eQTL |
| rs60862734 | chr15:95203701:C:T | - | 0.0549420286572119 | 0.0126526196620096 | LUAD | Female-baised eQTL |
| rs12324318 | chr15:95234486:C:T | - | 0.0473540396579093 | 0.0177776201062896 | LUAD | Female-baised eQTL |
| rs1579803 | chr15:86180342:T:C | - | 0.0537859793637131 | 0.0270442976105369 | LUAD | Female-baised eQTL |
| rs56805258 | chr15:86172150:T:C | - | 0.0524529090269418 | 0.0352942921719775 | LUAD | Female-baised eQTL |
| rs72759027 | chr15:88980031:G:T | - | 0.0480303699979677 | 0.0483283835148003 | LUAD | Female-baised eQTL |
| rs111419948 | chr15:88980064:T:C | - | 0.0480303699979677 | 0.0483283835148003 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6496742 | chr15:90979806:C:T | - | 0.04179355135109 | 0.0374600219655596 | HNSC | Male-baised eQTL |
| rs4611420 | chr15:86199991:G:A | - | 0.0393661399677981 | 0.0169586221542099 | KIRC | Male-baised eQTL |
| rs12917495 | chr15:85286330:G:A | - | 0.0440066477855904 | 0.0365932062620172 | KIRC | Male-baised eQTL |
| rs10163035 | chr15:85329038:A:G | - | 0.0399232706489831 | 0.0399291709595028 | KIRC | Male-baised eQTL |
| rs12441698 | chr15:85310470:G:A | - | 0.0400407011070281 | 0.0430277908928652 | KIRC | Male-baised eQTL |
| rs6497006 | chr15:85330306:T:C | - | 0.0395668811329733 | 0.0435386969768324 | KIRC | Male-baised eQTL |
| rs1986595 | chr15:85862473:A:G | - | 0.0910316289469643 | 0.0351761427945175 | BLCA | Male-baised eQTL |
| rs73445838 | chr15:85860532:G:A | - | 0.0898806060687545 | 0.0380940571006217 | BLCA | Male-baised eQTL |
| rs4843123 | chr15:85860925:G:A | - | 0.0898806060687545 | 0.0380940571006217 | BLCA | Male-baised eQTL |
| rs4842904 | chr15:85861103:C:A | - | 0.0898806060687545 | 0.0380940571006217 | BLCA | Male-baised eQTL |
| rs10152888 | chr15:85861724:C:G | - | 0.0898806060687545 | 0.0380940571006217 | BLCA | Male-baised eQTL |
| rs8024866 | chr15:85862845:G:A | - | 0.0898806060687545 | 0.0380940571006217 | BLCA | Male-baised eQTL |
| rs16945393 | chr15:85863050:G:A | - | 0.0898806060687545 | 0.0380940571006217 | BLCA | Male-baised eQTL |
| rs61066917 | chr15:85863456:G:A | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs8032095 | chr15:85863621:A:G | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs8032211 | chr15:85863647:A:G | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs8032224 | chr15:85863673:A:G | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs8031852 | chr15:85863838:C:G | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs73445847 | chr15:85864070:C:A | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs73445849 | chr15:85864270:C:A | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs57010492 | chr15:85864506:G:A | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs56091151 | chr15:85864647:C:T | - | 0.0897495174884512 | 0.0388022917731826 | BLCA | Male-baised eQTL |
| rs1483581 | chr15:85521678:T:C | - | 0.085012726284332 | 0.00265542163134254 | LUAD | Male-baised eQTL |
| rs66739423 | chr15:85522752:T:A | - | 0.085012726284332 | 0.00265542163134254 | LUAD | Male-baised eQTL |
| rs7162739 | chr15:85521798:T:A | - | 0.0846819254703641 | 0.00292114985074269 | LUAD | Male-baised eQTL |
| rs1994158 | chr15:85521096:A:G | - | 0.0785736501702776 | 0.0359285581017439 | LUAD | Male-baised eQTL |
| rs6496051 | chr15:85526545:A:T | - | 0.0721173190271615 | 0.0361374453861608 | LUAD | Male-baised eQTL |
| rs67853723 | chr15:94798787:A:C | - | 0.0927654551864795 | 0.0419368044444885 | LUAD | Male-baised eQTL |
| rs72752108 | chr15:86190691:C:T | - | -0.0869269109058814 | 0.0450266076084393 | LUAD | Male-baised eQTL |
| rs8037636 | chr15:85520214:G:A | - | 0.0733196391265776 | 0.0463266831440709 | LUAD | Male-baised eQTL |
| rs28630816 | chr15:94798827:G:A | - | 0.091880358680685 | 0.0469476601621411 | LUAD | Male-baised eQTL |
| rs3743447 | chr15:91007723:C:G | - | 0.0707850770288863 | 0.0480070108198447 | LUAD | Male-baised eQTL |
| rs756426 | chr15:85509439:G:T | - | 0.0747776036647997 | 0.0488636195948336 | LUAD | Male-baised eQTL |
| rs6496994 | chr15:92840510:T:A | - | -0.048014217491988 | 0.00730285322325422 | COAD | Male-baised eQTL |
| rs8029814 | chr15:100317536:C:G | - | -0.109645987040945 | 0.0111593563350508 | COAD | Male-baised eQTL |
| rs783528 | chr15:82600340:G:A | - | -0.0551362406216818 | 0.0155404807651425 | COAD | Male-baised eQTL |
| rs6496825 | chr15:91545988:C:G | - | -0.0467050239136995 | 0.0228347979094583 | COAD | Male-baised eQTL |
| rs12907047 | chr15:99472096:C:T | - | -0.0631478437975522 | 0.027130405385512 | COAD | Male-baised eQTL |
| rs11856487 | chr15:93883968:G:C | - | -0.044325128473558 | 0.0294612471956655 | COAD | Male-baised eQTL |
| rs11852436 | chr15:86890490:C:T | - | 0.0540321070145983 | 0.0298270861648088 | COAD | Male-baised eQTL |
| rs17645592 | chr15:86853291:C:T | - | -0.0856651376578773 | 0.0375662037689216 | COAD | Male-baised eQTL |
| rs11073822 | chr15:84934053:C:A | - | 0.0647429114176772 | 0.03993542320037 | COAD | Male-baised eQTL |
| rs8024609 | chr15:99471203:C:T | - | -0.0612509665023781 | 0.0447577087117857 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000140553 |
| CpG Site: cg00526711 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.0577946071481062 | |
 | Gene ID: ENSG00000140553 |
| CpG Site: cg06480138 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.415663723972095 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg00526711 | chr15:90934668 | gene,enhancer | -0.0577946071481062 | 1.39402154976661e-05 | -0.3451422735633933 | 1.9741178520143142e-08 | LUAD |
| cg06480138 | chr15:90933918 | gene,enhancer | -0.415663723972095 | 2.93473831307017e-15 | -0.6017157540031749 | 5.208070541204126e-19 | SKCM |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of UNC45A |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
