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Gene: ENSG00000139193 |
Summary for CD27 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000139193 | Gene symbol | CD27 |
| Gene name | CD27 molecule | |
| HGNC | 11922 | |
| Entrez ID | 939 | |
| Gene type | protein_coding | |
| Synonyms | CD27|S152|Tp55 | |
| UniProtAcc | P26842 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for CD27 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CD27 | 3.46e+02 | -1.66e+00 | 4.51e-01 | -3.69e+00 | 2.25e-04 | 3.86e-03 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CD27 | 3.32e+02 | 1.10e+00 | 2.90e-01 | 3.90e+00 | 9.40e-05 | 2.50e-04 | HNSC |
| CD27 | 5.47e+02 | -1.54e+00 | 3.30e-01 | -4.67e+00 | 3.01e-06 | 1.54e-05 | STAD |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CD27 | 1.67e+02 | 1.42e+00 | 5.09e-01 | 2.80e+00 | 5.12e-03 | 1.89e-02 | KIRP |
| CD27 | 3.32e+02 | 1.04e+00 | 1.50e-01 | 6.93e+00 | 4.07e-12 | 9.66e-12 | BRCA |
| CD27 | 1.23e+02 | -1.55e+00 | 4.61e-01 | -3.37e+00 | 7.41e-04 | 2.69e-03 | READ |
Top |
Sex-biased somatic mutation for CD27 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for CD27 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg18849517 | chr12:6443926 | CGI:chr12:6470389-6471263 | promoter | 5.33e-01 | 6.44e-01 | -2.13e+00 | 3.30e-02 | 4.26e-02 | -1.11e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg06495803 | chr12:6444323 | CGI:chr12:6470389-6471263 | promoter | 6.20e-01 | 7.69e-01 | -4.32e+00 | 1.55e-05 | 5.48e-05 | -1.49e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg03724640 | chr12:6443979 | CGI:chr12:6470389-6471263 | promoter | 6.29e-01 | 7.44e-01 | -2.32e+00 | 2.04e-02 | 2.79e-02 | -1.14e-01 |
| COAD | cg18849517 | chr12:6443926 | CGI:chr12:6470389-6471263 | promoter | 4.53e-01 | 5.56e-01 | -2.35e+00 | 1.86e-02 | 2.47e-02 | -1.03e-01 |
| BLCA | cg03724640 | chr12:6443979 | CGI:chr12:6470389-6471263 | promoter | 6.98e-01 | 5.71e-01 | 2.82e+00 | 4.82e-03 | 1.12e-02 | 1.28e-01 |
| BLCA | cg11384427 | chr12:6444419 | CGI:chr12:6470389-6471263 | promoter | 8.68e-01 | 7.67e-01 | 2.92e+00 | 3.55e-03 | 9.35e-03 | 1.01e-01 |
Top |
Exon skipping events with PSI in TCGA for CD27 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for CD27 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for CD27 |
| TFs related to CD27. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CD27 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for CD27 |
| RBPs related to ES in CD27. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CD27 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs4763280 | chr12:9708809:A:G | - | -0.233127263823273 | 0.0144486891151972 | HNSC | Female-baised eQTL |
| rs74524411 | chr12:13481831:A:G | - | 0.123415221635962 | 0.0187999373198862 | SARC | Female-baised eQTL |
| rs11055390 | chr12:13376702:T:C | - | 0.19789263964776 | 0.0264606397899446 | KIRP | Female-baised eQTL |
| rs11055391 | chr12:13377516:C:T | - | 0.19789263964776 | 0.0264606397899446 | KIRP | Female-baised eQTL |
| rs76863902 | chr12:13378314:C:T | - | 0.19789263964776 | 0.0264606397899446 | KIRP | Female-baised eQTL |
| rs11055393 | chr12:13379054:G:A | - | 0.19789263964776 | 0.0264606397899446 | KIRP | Female-baised eQTL |
| rs2087052 | chr12:13036813:C:T | - | 0.45224382049484 | 0.0380781270101249 | KIRP | Female-baised eQTL |
| rs117928580 | chr12:577762:G:T | - | 0.19048017318743 | 2.32410726178023e-05 | LIHC | Female-baised eQTL |
| rs374618530 | chr12:590969:G:A | - | 0.157710642268471 | 0.000974244263026513 | LIHC | Female-baised eQTL |
| rs79507080 | chr12:591920:A:G | - | 0.157710642268471 | 0.000974244263026513 | LIHC | Female-baised eQTL |
| rs79021866 | chr12:572091:C:T | - | 0.155078393599652 | 0.00158480927196933 | LIHC | Female-baised eQTL |
| rs61916660 | chr12:604511:A:G | - | 0.117376986708634 | 0.0291267755592419 | LIHC | Female-baised eQTL |
| rs73041069 | chr12:1178808:C:T | - | 0.163169706561259 | 0.0487512300171565 | LIHC | Female-baised eQTL |
| rs73041065 | chr12:1174145:G:C | - | 0.163154553903808 | 0.0489636534398114 | LIHC | Female-baised eQTL |
| rs55762607 | chr12:1175267:G:A | - | 0.163154553903808 | 0.0489636534398114 | LIHC | Female-baised eQTL |
| rs56099313 | chr12:1175350:G:A | - | 0.163154553903808 | 0.0489636534398114 | LIHC | Female-baised eQTL |
| rs11053497 | chr12:9884116:G:A | - | 0.120201276952903 | 0.000550906321378744 | STAD | Female-baised eQTL |
| rs11053498 | chr12:9886057:G:A | - | 0.120201276952903 | 0.000550906321378744 | STAD | Female-baised eQTL |
| rs58882780 | chr12:9795319:C:G | - | 0.118299172497877 | 0.000598241363418645 | STAD | Female-baised eQTL |
| rs4519177 | chr12:13173927:T:C | - | 0.10151860937227 | 0.00163176273134178 | STAD | Female-baised eQTL |
| rs12228747 | chr12:13173433:G:A | - | 0.103363273930536 | 0.00163667423475589 | STAD | Female-baised eQTL |
| rs11055263 | chr12:13174439:A:G | - | 0.10325118109626 | 0.00167894144103766 | STAD | Female-baised eQTL |
| rs79975967 | chr12:13175291:A:G | - | 0.10325118109626 | 0.00167894144103766 | STAD | Female-baised eQTL |
| rs11055266 | chr12:13176448:G:T | - | 0.10325118109626 | 0.00167894144103766 | STAD | Female-baised eQTL |
| rs11055260 | chr12:13172387:G:A | - | 0.102871580992778 | 0.0018035471917197 | STAD | Female-baised eQTL |
| rs11055261 | chr12:13172462:G:C | - | 0.102871580992778 | 0.0018035471917197 | STAD | Female-baised eQTL |
| rs74063255 | chr12:13176679:G:A | - | 0.102760472931302 | 0.00185381173569929 | STAD | Female-baised eQTL |
| rs11055267 | chr12:13176921:A:G | - | 0.102760472931302 | 0.00185381173569929 | STAD | Female-baised eQTL |
| rs11053499 | chr12:9895466:A:C | - | 0.0969347357977811 | 0.00635853429312958 | STAD | Female-baised eQTL |
| rs77242821 | chr12:13143794:C:T | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs78144644 | chr12:13143896:G:A | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs79050792 | chr12:13144012:A:G | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs79175222 | chr12:13144405:T:C | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs75466685 | chr12:13144628:T:C | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs76770299 | chr12:13147056:C:T | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs78221069 | chr12:13148879:T:C | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs78320209 | chr12:13149070:T:A | - | 0.155799840023349 | 0.00699614302462861 | STAD | Female-baised eQTL |
| rs11055268 | chr12:13177313:T:C | - | 0.0784519215585455 | 0.0157857201328467 | STAD | Female-baised eQTL |
| rs73300822 | chr12:13145588:C:G | - | 0.133005604119681 | 0.0180571585593883 | STAD | Female-baised eQTL |
| rs57144794 | chr12:9798132:A:C | - | 0.0849726148302987 | 0.0196873273991885 | STAD | Female-baised eQTL |
| rs78155120 | chr12:9798139:A:G | - | 0.0849726148302987 | 0.0196873273991885 | STAD | Female-baised eQTL |
| rs16907191 | chr12:9796640:C:G | - | 0.0832619927517454 | 0.0275062103392412 | STAD | Female-baised eQTL |
| rs56053011 | chr12:9800927:C:G | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs145440602 | chr12:9801243:A:G | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs116257121 | chr12:9801687:A:G | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs57451228 | chr12:9806006:A:G | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs79925841 | chr12:9806925:C:T | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs74062765 | chr12:9808145:G:A | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs56400313 | chr12:9808394:A:G | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs61361909 | chr12:9809556:G:A | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs7139009 | chr12:9809875:G:T | - | 0.0812515134170781 | 0.0308169222333566 | STAD | Female-baised eQTL |
| rs1558907 | chr12:13947259:G:T | - | 0.0865158641387038 | 0.0314226381597322 | STAD | Female-baised eQTL |
| rs17459247 | chr12:9807355:C:T | - | 0.0803390928521117 | 0.0365993522603783 | STAD | Female-baised eQTL |
| rs60183299 | chr12:9808738:A:G | - | 0.0803390928521117 | 0.0365993522603783 | STAD | Female-baised eQTL |
| rs58848817 | chr12:9806176:A:C | - | 0.0782855370865818 | 0.0423894015987073 | STAD | Female-baised eQTL |
| rs17807354 | chr12:9810889:T:A | - | 0.0780105455027345 | 0.0438769849653933 | STAD | Female-baised eQTL |
| rs10845863 | chr12:13926005:C:T | - | 0.0813308173041236 | 0.0453432091108409 | STAD | Female-baised eQTL |
| rs1558906 | chr12:13947100:T:C | - | 0.0824552555654777 | 0.0474543968428339 | STAD | Female-baised eQTL |
| rs1558908 | chr12:13947503:C:T | - | 0.0824552555654777 | 0.0474543968428339 | STAD | Female-baised eQTL |
| rs118178196 | chr12:10896764:A:G | - | 0.100900830406007 | 0.0321604574851739 | BLCA | Female-baised eQTL |
| rs55748583 | chr12:10987113:T:C | - | 0.0906214578832073 | 0.0477268124574615 | BLCA | Female-baised eQTL |
| rs73051630 | chr12:10994589:G:A | - | 0.0906214578832073 | 0.0477268124574615 | BLCA | Female-baised eQTL |
| rs73053768 | chr12:11003148:A:G | - | 0.0906214578832073 | 0.0477268124574615 | BLCA | Female-baised eQTL |
| rs73053785 | chr12:11009812:T:C | - | 0.0906214578832073 | 0.0477268124574615 | BLCA | Female-baised eQTL |
| rs3911150 | chr12:11049649:C:T | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs116607079 | chr12:11109445:C:T | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs73066828 | chr12:11118055:A:C | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs73066852 | chr12:11123942:A:G | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs117212341 | chr12:11129957:C:G | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs115781584 | chr12:11151961:C:T | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs73051387 | chr12:11161864:A:T | - | 0.0904398069243822 | 0.0493171067632483 | BLCA | Female-baised eQTL |
| rs55783481 | chr12:3613373:G:A | - | 0.14042592050656 | 0.0133589845534047 | COAD | Female-baised eQTL |
| rs56349377 | chr12:3620143:C:T | - | 0.129797646198379 | 0.0396130896048317 | COAD | Female-baised eQTL |
| rs55714330 | chr12:3620160:G:C | - | 0.129797646198379 | 0.0396130896048317 | COAD | Female-baised eQTL |
| rs73045254 | chr12:3617313:T:G | - | 0.126108168225481 | 0.0411374736048267 | COAD | Female-baised eQTL |
| rs55837225 | chr12:3613241:G:C | - | 0.127191393317532 | 0.0484452862845401 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12311224 | chr12:4949794:T:A | - | 0.208606695950059 | 0.0218281053296384 | READ | Male-baised eQTL |
| rs11063422 | chr12:4950184:T:C | - | 0.208606695950059 | 0.0218281053296384 | READ | Male-baised eQTL |
| rs10492066 | chr12:4951104:T:C | - | 0.208074083392262 | 0.023405322697451 | READ | Male-baised eQTL |
| rs12315875 | chr12:4949704:G:A | - | 0.200037717092014 | 0.0315232124078197 | READ | Male-baised eQTL |
| rs10849180 | chr12:4949470:A:T | - | 0.197664703943912 | 0.0380012809604146 | READ | Male-baised eQTL |
| rs10849179 | chr12:4948832:C:T | - | 0.197898226293829 | 0.0381712639803329 | READ | Male-baised eQTL |
| rs11063421 | chr12:4949227:T:C | - | 0.197898226293829 | 0.0381712639803329 | READ | Male-baised eQTL |
| rs17819589 | chr12:12963446:T:C | - | 0.194406780832945 | 0.00184777535100004 | SARC | Male-baised eQTL |
| rs78082571 | chr12:4953984:A:G | - | 0.130411232054154 | 0.0269707646034295 | SARC | Male-baised eQTL |
| rs4766316 | chr12:4954614:T:A | - | 0.130411232054154 | 0.0269707646034295 | SARC | Male-baised eQTL |
| rs77530592 | chr12:4963871:G:C | - | 0.127868860086663 | 0.0350299707137024 | SARC | Male-baised eQTL |
| rs80226380 | chr12:4963136:C:T | - | 0.127946557009353 | 0.0350538026319888 | SARC | Male-baised eQTL |
| rs3764028 | chr12:13982130:T:G | - | -0.286350477343923 | 0.0427302232878529 | SARC | Male-baised eQTL |
| rs3983616 | chr12:10371938:T:A | - | 0.0599129793428083 | 0.0062733779532018 | LIHC | Male-baised eQTL |
| rs253844 | chr12:15482801:T:C | - | 0.0659969048367613 | 0.0073749332701301 | LIHC | Male-baised eQTL |
| rs6488287 | chr12:10462042:A:G | - | -0.0532141281877199 | 0.0351628367541211 | LIHC | Male-baised eQTL |
| rs139351716 | chr12:10465503:A:T | - | -0.0532141281877199 | 0.0351628367541211 | LIHC | Male-baised eQTL |
| rs7134846 | chr12:10462200:A:G | - | -0.0529140581884424 | 0.0373336827915893 | LIHC | Male-baised eQTL |
| rs56052449 | chr12:15013482:G:A | - | 0.0416682322866341 | 0.0210996100022133 | BLCA | Male-baised eQTL |
| rs34615955 | chr12:15016329:C:T | - | 0.0415548061558044 | 0.0219292665607679 | BLCA | Male-baised eQTL |
| rs75100711 | chr12:15011879:T:C | - | 0.0405899069967748 | 0.0232915172744535 | BLCA | Male-baised eQTL |
| rs12814190 | chr12:15011852:C:A | - | 0.0406008246639561 | 0.0233540752639583 | BLCA | Male-baised eQTL |
| rs1981755 | chr12:15014243:G:A | - | 0.0404885974094992 | 0.0242723691540546 | BLCA | Male-baised eQTL |
| rs7966737 | chr12:15017195:T:C | - | 0.0404885974094992 | 0.0242723691540546 | BLCA | Male-baised eQTL |
| rs35201625 | chr12:15017498:T:C | - | 0.0404885974094992 | 0.0242723691540546 | BLCA | Male-baised eQTL |
| rs7977086 | chr12:15010378:G:T | - | 0.0402451997441236 | 0.0247092595766577 | BLCA | Male-baised eQTL |
| rs73070150 | chr12:15009959:G:A | - | 0.0405178157024347 | 0.0270638681769331 | BLCA | Male-baised eQTL |
| rs968655 | chr12:15007824:G:T | - | 0.0397603907281687 | 0.0323677195073332 | BLCA | Male-baised eQTL |
| rs1558788 | chr12:15015938:C:T | - | -0.0391430793340613 | 0.0334548189925525 | BLCA | Male-baised eQTL |
| rs1468851 | chr12:15016483:C:G | - | -0.0391430793340613 | 0.0334548189925525 | BLCA | Male-baised eQTL |
| rs112843795 | chr12:10152217:G:A | - | 0.0476998158828029 | 0.0360965063153114 | BLCA | Male-baised eQTL |
| rs11053639 | chr12:10153459:A:G | - | 0.047615509450959 | 0.0366199007717737 | BLCA | Male-baised eQTL |
| rs11053640 | chr12:10153600:C:T | - | 0.047615509450959 | 0.0366199007717737 | BLCA | Male-baised eQTL |
| rs12305247 | chr12:10148755:A:G | - | 0.0475954194937737 | 0.0370838921323564 | BLCA | Male-baised eQTL |
| rs12300193 | chr12:10149574:C:T | - | 0.0475954194937737 | 0.0370838921323564 | BLCA | Male-baised eQTL |
| rs76675771 | chr12:10150220:T:C | - | 0.0475954194937737 | 0.0370838921323564 | BLCA | Male-baised eQTL |
| rs58564240 | chr12:10150963:T:C | - | 0.0475954194937737 | 0.0370838921323564 | BLCA | Male-baised eQTL |
| rs79161256 | chr12:10151903:C:T | - | 0.0475954194937737 | 0.0370838921323564 | BLCA | Male-baised eQTL |
| rs11053642 | chr12:10153692:T:C | - | 0.0475285782456431 | 0.0374477684972209 | BLCA | Male-baised eQTL |
| rs1468852 | chr12:15014590:G:T | - | -0.0380188172954159 | 0.0429361813720859 | BLCA | Male-baised eQTL |
| rs12099751 | chr12:15020900:G:A | - | 0.038552614593762 | 0.0437950209118538 | BLCA | Male-baised eQTL |
| rs12099620 | chr12:15020907:A:G | - | 0.038552614593762 | 0.0437950209118538 | BLCA | Male-baised eQTL |
| rs12372791 | chr12:9351698:C:G | - | 0.084653003447073 | 0.0381157183034204 | COAD | Male-baised eQTL |
| rs11050397 | chr12:9349694:G:C | - | 0.0844871733391362 | 0.0385413293074882 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000139193 |
| CpG Site: cg18849517 | |
| Position to Gene: promoter | |
| Male Effect: -0.428056266185771 | |
| Female Effect: - | |
 | Gene ID: ENSG00000139193 |
| CpG Site: cg03724640 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.487221750658308 | |
 | Gene ID: ENSG00000139193 |
| CpG Site: cg11384427 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.487113855439516 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg18849517 | chr12:6443926 | promoter | -0.428056266185771 | 3.69983656330913e-05 | -0.33870403405925875 | 2.1772279222463598e-07 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg03724640 | chr12:6443979 | promoter | -0.487221750658308 | 2.79029798691276e-53 | -0.944361411656193 | 2.2848762567473973e-57 | STAD |
| cg11384427 | chr12:6444419 | promoter | -0.487113855439516 | 3.32136009941978e-53 | -0.9444885290183959 | 6.146241164437201e-57 | STAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of CD27 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000139193 | CD27 | C0006625 | Cachexia | 1 | CTD_human |
| ENSG00000139193 | CD27 | C3554540 | LYMPHOPROLIFERATIVE SYNDROME 2 | 1 | CTD_human |
