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Gene: ENSG00000138356 |
Summary for AOX1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000138356 | Gene symbol | AOX1 |
| Gene name | aldehyde oxidase 1 | |
| HGNC | 553 | |
| Entrez ID | 316 | |
| Gene type | protein_coding | |
| Synonyms | AOX1|AO|AOH1 | |
| UniProtAcc | Q06278 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000138356 | AOX1 | DB00924 | Cyclobenzaprine | SmallMoleculeDrug |
| ENSG00000138356 | AOX1 | DB03516 | Eniluracil | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for AOX1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| AOX1 | 4.43e+03 | 1.05e+00 | 1.43e-01 | 7.30e+00 | 2.91e-13 | 3.47e-11 | KIRC |
| AOX1 | 4.28e+03 | 1.76e+00 | 2.41e-01 | 7.28e+00 | 3.24e-13 | 4.31e-11 | KIRP |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| AOX1 | 5.69e+02 | -2.86e+00 | 7.29e-01 | -3.92e+00 | 8.68e-05 | 8.97e-04 | ESCA |
| AOX1 | 2.86e+04 | -5.15e+00 | 5.80e-01 | -8.88e+00 | 6.44e-19 | 5.90e-17 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| AOX1 | 2.59e+02 | -2.30e+00 | 6.89e-01 | -3.34e+00 | 8.30e-04 | 7.24e-03 | BLCA |
| AOX1 | 9.72e+02 | -2.23e+00 | 1.61e-01 | -1.39e+01 | 1.19e-43 | 9.82e-43 | BRCA |
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Sex-biased somatic mutation for AOX1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for AOX1 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRP | cg01217071 | chr2:200585600 | CGI:chr2:200585803-200586304 | promoter | 3.80e-01 | 2.70e-01 | 2.95e+00 | 3.16e-03 | 1.04e-02 | 1.10e-01 |
| KIRP | cg27547291 | chr2:200586303 | CGI:chr2:200585803-200586304 | promoter,gene body | 3.71e-01 | 2.33e-01 | 6.47e+00 | 9.50e-11 | 1.26e-09 | 1.38e-01 |
| KIRP | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 5.45e-01 | 3.69e-01 | 7.00e+00 | 2.49e-12 | 3.48e-11 | 1.76e-01 |
| ESCA | cg14383422 | chr2:200586239 | CGI:chr2:200585803-200586304 | promoter,gene body | 3.26e-01 | 2.24e-01 | 2.00e+00 | 4.51e-02 | 4.88e-02 | 1.03e-01 |
| MESO | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 3.28e-01 | 4.31e-01 | -2.17e+00 | 3.02e-02 | 4.44e-02 | -1.03e-01 |
| DLBC | cg01217071 | chr2:200585600 | CGI:chr2:200585803-200586304 | promoter | 7.24e-01 | 6.08e-01 | 2.17e+00 | 2.98e-02 | 4.20e-02 | 1.16e-01 |
| CHOL | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 6.07e-01 | 5.03e-01 | 2.42e+00 | 1.55e-02 | 2.83e-02 | 1.04e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg14383422 | chr2:200586239 | CGI:chr2:200585803-200586304 | promoter,gene body | 1.40e-01 | 2.23e-02 | 2.51e+00 | 1.22e-02 | 1.62e-02 | 1.18e-01 |
| LUSC | cg27547291 | chr2:200586303 | CGI:chr2:200585803-200586304 | promoter,gene body | 3.59e-01 | 2.16e-01 | 3.05e+00 | 2.31e-03 | 4.62e-03 | 1.43e-01 |
| LUSC | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 5.46e-01 | 3.62e-01 | 3.82e+00 | 1.36e-04 | 8.00e-04 | 1.84e-01 |
| BLCA | cg09729613 | chr2:200585878 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 2.02e-01 | 2.00e-02 | 2.32e+00 | 2.04e-02 | 2.48e-02 | 1.82e-01 |
| BLCA | cg04380340 | chr2:200585783 | CGI:chr2:200585803-200586304 | promoter | 2.39e-01 | 6.29e-02 | 2.12e+00 | 3.42e-02 | 3.72e-02 | 1.76e-01 |
| BLCA | cg08952506 | chr2:200585887 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 2.09e-01 | 5.06e-02 | 2.58e+00 | 9.78e-03 | 1.39e-02 | 1.58e-01 |
| BLCA | cg02144933 | chr2:200585967 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 2.16e-01 | 4.16e-02 | 3.42e+00 | 6.22e-04 | 1.57e-03 | 1.74e-01 |
| BLCA | cg12627583 | chr2:200586008 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 2.93e-01 | 7.94e-02 | 3.31e+00 | 9.21e-04 | 2.13e-03 | 2.13e-01 |
| CHOL | cg14383422 | chr2:200586239 | CGI:chr2:200585803-200586304 | promoter,gene body | 2.57e-01 | 2.56e-02 | 2.14e+00 | 3.25e-02 | 3.87e-02 | 2.31e-01 |
| CHOL | cg04380340 | chr2:200585783 | CGI:chr2:200585803-200586304 | promoter | 1.61e-01 | 5.80e-02 | 2.21e+00 | 2.70e-02 | 3.50e-02 | 1.03e-01 |
| CHOL | cg27547291 | chr2:200586303 | CGI:chr2:200585803-200586304 | promoter,gene body | 4.46e-01 | 2.20e-01 | 2.36e+00 | 1.83e-02 | 2.92e-02 | 2.26e-01 |
| CHOL | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 5.03e-01 | 2.69e-01 | 2.65e+00 | 7.96e-03 | 1.92e-02 | 2.34e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg14383422 | chr2:200586239 | CGI:chr2:200585803-200586304 | promoter,gene body | 2.73e-01 | 3.44e-02 | 1.04e+01 | 2.51e-25 | 2.20e-24 | 2.39e-01 |
| BRCA | cg04380340 | chr2:200585783 | CGI:chr2:200585803-200586304 | promoter | 1.50e-01 | 4.66e-02 | 8.99e+00 | 2.56e-19 | 1.31e-18 | 1.03e-01 |
| BRCA | cg12627583 | chr2:200586008 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 1.76e-01 | 7.45e-02 | 7.45e+00 | 9.00e-14 | 2.99e-13 | 1.01e-01 |
| BRCA | cg27547291 | chr2:200586303 | CGI:chr2:200585803-200586304 | promoter,gene body | 5.03e-01 | 2.66e-01 | 1.17e+01 | 8.26e-32 | 1.51e-30 | 2.38e-01 |
| BRCA | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 5.90e-01 | 3.34e-01 | 1.44e+01 | 3.67e-47 | 6.42e-44 | 2.56e-01 |
| HNSC | cg13000082 | chr2:200585804 | CGI:chr2:200585803-200586304 | promoter | 2.07e-01 | 7.42e-02 | 2.17e+00 | 2.99e-02 | 3.54e-02 | 1.33e-01 |
| HNSC | cg02144933 | chr2:200585967 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 1.55e-01 | 5.00e-02 | 2.17e+00 | 2.99e-02 | 3.54e-02 | 1.05e-01 |
| HNSC | cg12627583 | chr2:200586008 | CGI:chr2:200585803-200586304 | UTR,promoter,exon,gene body | 2.02e-01 | 8.08e-02 | 2.27e+00 | 2.30e-02 | 3.00e-02 | 1.21e-01 |
| HNSC | cg27547291 | chr2:200586303 | CGI:chr2:200585803-200586304 | promoter,gene body | 3.85e-01 | 2.45e-01 | 2.27e+00 | 2.30e-02 | 3.00e-02 | 1.40e-01 |
| BLCA | cg24569637 | chr2:200585837 | CGI:chr2:200585803-200586304 | promoter | 1.50e-01 | 3.74e-02 | 2.27e+00 | 2.33e-02 | 3.00e-02 | 1.12e-01 |
| BLCA | cg08266417 | chr2:200585852 | CGI:chr2:200585803-200586304 | promoter | 1.67e-01 | 3.21e-02 | 2.26e+00 | 2.40e-02 | 3.06e-02 | 1.35e-01 |
| KIRP | cg14383422 | chr2:200586239 | CGI:chr2:200585803-200586304 | promoter,gene body | 1.26e-01 | 1.80e-02 | 2.71e+00 | 6.79e-03 | 1.30e-02 | 1.08e-01 |
| KIRP | cg27547291 | chr2:200586303 | CGI:chr2:200585803-200586304 | promoter,gene body | 3.71e-01 | 1.95e-01 | 3.01e+00 | 2.63e-03 | 7.06e-03 | 1.75e-01 |
| KIRP | cg22953017 | chr2:200586580 | CGI:chr2:200585803-200586304 | promoter,gene body | 5.45e-01 | 3.38e-01 | 3.66e+00 | 2.55e-04 | 1.81e-03 | 2.07e-01 |
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Exon skipping events with PSI in TCGA for AOX1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for AOX1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for AOX1 |
| TFs related to AOX1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ALX3 | AOX1 | 4.95e+00 | 9.89e-01 | 4.12e+00 | 8.66e-03 | Male-biased |
| ACC | FOXA1 | AOX1 | 3.92e+00 | 9.81e-01 | 2.98e+00 | 5.32e-03 | Male-biased |
| ACC | FOXA3 | AOX1 | 3.96e+00 | 9.82e-01 | 3.04e+00 | 5.72e-03 | Male-biased |
| ACC | FOXG1 | AOX1 | 3.84e+00 | 9.83e-01 | 2.61e+00 | 1.50e-03 | Male-biased |
| ACC | LHX8 | AOX1 | 5.59e+00 | 9.82e-01 | 4.90e+00 | 1.64e-02 | Male-biased |
| ACC | MIXL1 | AOX1 | 4.95e+00 | 9.81e-01 | 4.26e+00 | 1.66e-02 | Male-biased |
| ACC | NKX3-1 | AOX1 | 4.40e+00 | 9.89e-01 | 3.45e+00 | 5.21e-03 | Male-biased |
| ACC | PHOX2B | AOX1 | 4.26e+00 | 9.86e-01 | 3.35e+00 | 6.25e-03 | Male-biased |
| ACC | POU3F2 | AOX1 | 3.86e+00 | 9.82e-01 | 2.76e+00 | 2.69e-03 | Male-biased |
| ACC | POU5F1 | AOX1 | 4.17e+00 | 9.83e-01 | 3.33e+00 | 8.32e-03 | Male-biased |
| ACC | PROP1 | AOX1 | 4.81e+00 | 9.86e-01 | 4.02e+00 | 1.07e-02 | Male-biased |
| ACC | SOX2 | AOX1 | 4.23e+00 | 9.86e-01 | 3.33e+00 | 6.42e-03 | Male-biased |
| ACC | SOX21 | AOX1 | 4.21e+00 | 9.82e-01 | 3.41e+00 | 9.80e-03 | Male-biased |
| ACC | SOX4 | AOX1 | 3.99e+00 | 9.83e-01 | 3.04e+00 | 5.06e-03 | Male-biased |
| ACC | SOX7 | AOX1 | 4.11e+00 | 9.84e-01 | 3.21e+00 | 6.22e-03 | Male-biased |
| ACC | SRY | AOX1 | 4.40e+00 | 9.86e-01 | 3.53e+00 | 7.49e-03 | Male-biased |
| ACC | ZNF25 | AOX1 | 3.87e+00 | 9.83e-01 | 2.73e+00 | 2.23e-03 | Male-biased |
| ACC | ZNF418 | AOX1 | 3.84e+00 | 9.83e-01 | 2.54e+00 | 1.13e-03 | Male-biased |
| CHOL | FOXA1 | AOX1 | 3.18e+00 | 3.27e-03 | 4.40e+00 | 9.90e-01 | Female-biased |
| CHOL | FOXA3 | AOX1 | 3.38e+00 | 5.83e-03 | 4.45e+00 | 9.88e-01 | Female-biased |
| CHOL | FOXG1 | AOX1 | 2.98e+00 | 5.99e-03 | 4.03e+00 | 9.82e-01 | Female-biased |
| CHOL | FOXR2 | AOX1 | 3.03e+00 | 7.12e-03 | 4.04e+00 | 9.81e-01 | Female-biased |
| CHOL | NANOG | AOX1 | 3.31e+00 | 8.26e-03 | 4.29e+00 | 9.84e-01 | Female-biased |
| CHOL | NKX3-1 | AOX1 | 3.80e+00 | 9.79e-03 | 4.74e+00 | 9.86e-01 | Female-biased |
| CHOL | PHOX2B | AOX1 | 3.81e+00 | 1.45e-02 | 4.65e+00 | 9.81e-01 | Female-biased |
| CHOL | POU3F2 | AOX1 | 3.27e+00 | 9.63e-03 | 4.21e+00 | 9.81e-01 | Female-biased |
| CHOL | POU5F1 | AOX1 | 3.55e+00 | 1.16e-02 | 4.45e+00 | 9.82e-01 | Female-biased |
| GBM | FOXA3 | AOX1 | 4.15e+00 | 9.83e-01 | 2.77e+00 | 3.89e-03 | Male-biased |
| GBM | NKX3-1 | AOX1 | 4.34e+00 | 9.83e-01 | 3.20e+00 | 8.25e-03 | Male-biased |
| GBM | PHOX2B | AOX1 | 4.45e+00 | 9.80e-01 | 3.42e+00 | 1.23e-02 | Male-biased |
| GBM | SOX2 | AOX1 | 4.47e+00 | 9.81e-01 | 3.43e+00 | 1.18e-02 | Male-biased |
| GBM | SRY | AOX1 | 4.56e+00 | 9.82e-01 | 3.53e+00 | 1.22e-02 | Male-biased |
| UVM | ALX3 | AOX1 | 5.41e+00 | 9.92e-01 | 3.62e+00 | 3.73e-03 | Male-biased |
| UVM | DPRX | AOX1 | 5.14e+00 | 9.82e-01 | 3.89e+00 | 1.15e-02 | Male-biased |
| UVM | FOXA1 | AOX1 | 4.85e+00 | 9.90e-01 | 2.09e+00 | 2.95e-04 | Male-biased |
| UVM | FOXA3 | AOX1 | 4.90e+00 | 9.91e-01 | 2.22e+00 | 3.68e-04 | Male-biased |
| UVM | FOXG1 | AOX1 | 4.55e+00 | 9.85e-01 | 1.83e+00 | 3.26e-04 | Male-biased |
| UVM | FOXR2 | AOX1 | 4.69e+00 | 9.88e-01 | 1.56e+00 | 9.97e-05 | Male-biased |
| UVM | HSFY2 | AOX1 | 4.89e+00 | 9.86e-01 | 3.27e+00 | 5.33e-03 | Male-biased |
| UVM | LHX8 | AOX1 | 6.05e+00 | 9.90e-01 | 4.67e+00 | 9.04e-03 | Male-biased |
| UVM | MIXL1 | AOX1 | 5.46e+00 | 9.91e-01 | 3.80e+00 | 5.04e-03 | Male-biased |
| UVM | MYNN | AOX1 | 4.49e+00 | 9.83e-01 | 2.21e+00 | 1.10e-03 | Male-biased |
| UVM | NANOG | AOX1 | 4.54e+00 | 9.84e-01 | 2.43e+00 | 1.70e-03 | Male-biased |
| UVM | NKX3-1 | AOX1 | 5.12e+00 | 9.93e-01 | 2.72e+00 | 8.29e-04 | Male-biased |
| UVM | PHOX2B | AOX1 | 5.03e+00 | 9.91e-01 | 2.85e+00 | 1.47e-03 | Male-biased |
| UVM | POU3F2 | AOX1 | 4.68e+00 | 9.88e-01 | 1.96e+00 | 3.31e-04 | Male-biased |
| UVM | POU5F1 | AOX1 | 4.76e+00 | 9.87e-01 | 2.69e+00 | 1.92e-03 | Male-biased |
| UVM | PROP1 | AOX1 | 5.31e+00 | 9.92e-01 | 3.52e+00 | 3.84e-03 | Male-biased |
| UVM | SOX2 | AOX1 | 4.97e+00 | 9.90e-01 | 2.84e+00 | 1.69e-03 | Male-biased |
| UVM | SOX21 | AOX1 | 4.82e+00 | 9.87e-01 | 2.98e+00 | 3.30e-03 | Male-biased |
| UVM | SOX4 | AOX1 | 4.57e+00 | 9.83e-01 | 2.69e+00 | 2.90e-03 | Male-biased |
| UVM | SOX7 | AOX1 | 4.79e+00 | 9.88e-01 | 2.58e+00 | 1.35e-03 | Male-biased |
| UVM | SRY | AOX1 | 5.16e+00 | 9.92e-01 | 3.08e+00 | 1.89e-03 | Male-biased |
| UVM | TBP | AOX1 | 4.53e+00 | 9.83e-01 | 2.55e+00 | 2.30e-03 | Male-biased |
| UVM | ZNF136 | AOX1 | 4.54e+00 | 9.83e-01 | 2.50e+00 | 2.01e-03 | Male-biased |
| UVM | ZNF25 | AOX1 | 4.71e+00 | 9.89e-01 | 1.77e+00 | 1.71e-04 | Male-biased |
| UVM | ZNF35 | AOX1 | 4.77e+00 | 9.89e-01 | 1.97e+00 | 2.57e-04 | Male-biased |
| UVM | ZNF418 | AOX1 | 5.03e+00 | 9.93e-01 | 4.80e-01 | 3.35e-06 | Male-biased |
| UVM | ZNF653 | AOX1 | 5.64e+00 | 9.85e-01 | 4.44e+00 | 1.28e-02 | Male-biased |
| UVM | ZNF879 | AOX1 | 4.40e+00 | 9.82e-01 | 7.81e-01 | 2.66e-05 | Male-biased |
| AOX1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for AOX1 |
| RBPs related to ES in AOX1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KIRP | LIN28A | exon_skip_332276 | 1.10e+01 | 1.60e-03 | 1.15e+01 | 9.98e-01 | Female-biased |
| AOX1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6741283 | chr2:203850087:C:T | - | 0.178188095827911 | 0.00342843409077738 | STAD | Female-baised eQTL |
| rs145459319 | chr2:208118633:C:T | - | 0.0738243992567549 | 0.00012264496109102 | LUAD | Female-baised eQTL |
| rs62192852 | chr2:208119478:C:G | - | 0.0738243992567549 | 0.00012264496109102 | LUAD | Female-baised eQTL |
| rs62192824 | chr2:208113236:C:T | - | 0.0738791727345724 | 0.000123656255825505 | LUAD | Female-baised eQTL |
| rs62192851 | chr2:208116127:G:A | - | 0.0717987425781755 | 0.000202884872662935 | LUAD | Female-baised eQTL |
| rs78081166 | chr2:208122114:C:A | - | 0.0715065506710956 | 0.000335786630207497 | LUAD | Female-baised eQTL |
| rs11679982 | chr2:208112790:A:T | - | -0.0657033842875711 | 0.000723274043332305 | LUAD | Female-baised eQTL |
| rs12624138 | chr2:208108287:A:G | - | -0.0656781328898624 | 0.000736239547867033 | LUAD | Female-baised eQTL |
| rs6711600 | chr2:208108599:A:G | - | -0.0656781328898624 | 0.000736239547867033 | LUAD | Female-baised eQTL |
| rs6711708 | chr2:208108663:A:G | - | -0.0656781328898624 | 0.000736239547867033 | LUAD | Female-baised eQTL |
| rs6711724 | chr2:208108727:A:G | - | -0.0656781328898624 | 0.000736239547867033 | LUAD | Female-baised eQTL |
| rs6759064 | chr2:208109237:T:C | - | -0.0656781328898624 | 0.000736239547867033 | LUAD | Female-baised eQTL |
| rs6435412 | chr2:208111684:T:C | - | -0.0656781328898624 | 0.000736239547867033 | LUAD | Female-baised eQTL |
| rs6751702 | chr2:208107839:T:C | - | -0.0646470970113184 | 0.00102517377137558 | LUAD | Female-baised eQTL |
| rs10190895 | chr2:208647603:T:G | - | 0.0642741729885251 | 0.00147055097315146 | LUAD | Female-baised eQTL |
| rs35962307 | chr2:208648551:A:T | - | 0.0642741729885251 | 0.00147055097315146 | LUAD | Female-baised eQTL |
| rs6435410 | chr2:208107159:G:A | - | -0.0625910025727724 | 0.00148652233215552 | LUAD | Female-baised eQTL |
| rs10192021 | chr2:208651705:G:T | - | 0.060363996983758 | 0.00300088573769206 | LUAD | Female-baised eQTL |
| rs11685027 | chr2:208644886:C:G | - | 0.0538838367357835 | 0.00368125533939475 | LUAD | Female-baised eQTL |
| rs72964195 | chr2:207827254:C:T | - | 0.075518963305621 | 0.0037191674776178 | LUAD | Female-baised eQTL |
| rs111630817 | chr2:207837548:T:G | - | 0.0617174462628969 | 0.0177709052969012 | LUAD | Female-baised eQTL |
| rs10176291 | chr2:208117352:A:G | - | 0.0470130781417026 | 0.0195749049653719 | LUAD | Female-baised eQTL |
| rs7602386 | chr2:200580866:T:A | - | 0.0369136825448505 | 0.0298961423447189 | LUAD | Female-baised eQTL |
| rs13030504 | chr2:200805555:G:A | - | 0.0264655517384843 | 0.0440962265747823 | LUAD | Female-baised eQTL |
| rs17233334 | chr2:198790332:T:A | - | 0.0325845290242219 | 0.04537824360139 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs112299403 | chr2:200543030:C:T | - | 0.261508593464544 | 0.0102341646425977 | PCPG | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000138356 |
| CpG Site: cg22953017 | |
| Position to Gene: gene,promoter | |
| Male Effect: - | |
| Female Effect: -0.186013066368022 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg22953017 | chr2:200586580 | gene,promoter | -0.186013066368022 | 3.18236736351065e-05 | -0.3265898594734788 | 9.467978450844063e-08 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of AOX1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000138356 | AOX1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| ENSG00000138356 | AOX1 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
