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Gene: ENSG00000137558 |
Summary for PI15 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000137558 | Gene symbol | PI15 |
| Gene name | peptidase inhibitor 15 | |
| HGNC | 8946 | |
| Entrez ID | 51050 | |
| Gene type | protein_coding | |
| Synonyms | PI15|P25TI | |
| UniProtAcc | O43692 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PI15 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PI15 | 2.49e+03 | -2.02e+00 | 6.94e-01 | -2.91e+00 | 3.63e-03 | 2.83e-02 | BRCA |
| PI15 | 6.83e+02 | 1.01e+00 | 1.94e-01 | 5.21e+00 | 1.86e-07 | 3.70e-05 | STAD |
| PI15 | 2.96e+03 | -1.10e+00 | 2.99e-01 | -3.68e+00 | 2.29e-04 | 3.10e-03 | SARC |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PI15 | 7.66e+02 | 1.41e+00 | 4.24e-01 | 3.33e+00 | 8.66e-04 | 2.49e-03 | STAD |
| PI15 | 7.80e+02 | -1.30e+00 | 5.13e-01 | -2.54e+00 | 1.10e-02 | 4.05e-02 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PI15 | 5.14e+02 | 2.26e+00 | 3.97e-01 | 5.68e+00 | 1.36e-08 | 2.57e-07 | HNSC |
| PI15 | 4.94e+03 | -1.01e+00 | 2.58e-01 | -3.91e+00 | 9.37e-05 | 1.44e-04 | BRCA |
Top |
Sex-biased somatic mutation for PI15 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PI15 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg10819495 | chr8:74823317 | CGI:chr8:74984293-74984881 | promoter | 3.20e-01 | 4.68e-01 | -2.20e+00 | 2.79e-02 | 3.98e-02 | -1.48e-01 |
| DLBC | cg09304624 | chr8:74823498 | CGI:chr8:74984293-74984881 | promoter | 4.48e-01 | 5.93e-01 | -1.99e+00 | 4.70e-02 | 4.89e-02 | -1.45e-01 |
| DLBC | cg24349665 | chr8:74824488 | CGI:chr8:74984293-74984881 | promoter | 1.53e-01 | 2.81e-01 | 3.77e+00 | 1.66e-04 | 7.39e-04 | -1.27e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg09304624 | chr8:74823498 | CGI:chr8:74984293-74984881 | promoter | 7.52e-01 | 8.70e-01 | -3.69e+00 | 2.28e-04 | 4.22e-04 | -1.18e-01 |
| KIRC | cg04893119 | chr8:74824066 | CGI:chr8:74984293-74984881 | promoter | 7.27e-01 | 8.45e-01 | -4.20e+00 | 2.73e-05 | 6.53e-05 | -1.17e-01 |
| LUAD | cg04893119 | chr8:74824066 | CGI:chr8:74984293-74984881 | promoter | 6.65e-01 | 7.87e-01 | -2.79e+00 | 5.28e-03 | 7.84e-03 | -1.22e-01 |
| LUAD | cg00128482 | chr8:74825221 | CGI:chr8:74984293-74984881 | UTR,promoter,exon,gene body | 4.01e-01 | 5.10e-01 | -3.53e+00 | 4.09e-04 | 9.16e-04 | -1.09e-01 |
| HNSC | cg04893119 | chr8:74824066 | CGI:chr8:74984293-74984881 | promoter | 5.32e-01 | 6.83e-01 | -3.68e+00 | 2.30e-04 | 5.23e-04 | -1.51e-01 |
| HNSC | cg00128482 | chr8:74825221 | CGI:chr8:74984293-74984881 | UTR,promoter,exon,gene body | 4.11e-01 | 5.99e-01 | -4.04e+00 | 5.45e-05 | 1.56e-04 | -1.88e-01 |
| LUSC | cg10819495 | chr8:74823317 | CGI:chr8:74984293-74984881 | promoter | 5.98e-01 | 4.86e-01 | 2.22e+00 | 2.65e-02 | 2.99e-02 | 1.12e-01 |
| LUSC | cg04893119 | chr8:74824066 | CGI:chr8:74984293-74984881 | promoter | 5.21e-01 | 7.93e-01 | -3.63e+00 | 2.82e-04 | 1.18e-03 | -2.73e-01 |
| LIHC | cg24349665 | chr8:74824488 | CGI:chr8:74984293-74984881 | promoter | 3.77e-01 | 2.25e-01 | 2.79e+00 | 5.23e-03 | 6.87e-03 | 1.52e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg10819495 | chr8:74823317 | CGI:chr8:74984293-74984881 | promoter | 3.20e-01 | 1.91e-01 | 7.79e+00 | 6.82e-15 | 2.46e-14 | 1.29e-01 |
| BRCA | cg09304624 | chr8:74823498 | CGI:chr8:74984293-74984881 | promoter | 7.68e-01 | 6.18e-01 | 9.97e+00 | 2.11e-23 | 1.54e-22 | 1.49e-01 |
| BRCA | cg04893119 | chr8:74824066 | CGI:chr8:74984293-74984881 | promoter | 4.06e-01 | 5.26e-01 | -6.72e+00 | 1.81e-11 | 5.04e-11 | -1.20e-01 |
| BLCA | cg04893119 | chr8:74824066 | CGI:chr8:74984293-74984881 | promoter | 4.48e-01 | 6.29e-01 | -2.51e+00 | 1.22e-02 | 1.98e-02 | -1.81e-01 |
| LIHC | cg10819495 | chr8:74823317 | CGI:chr8:74984293-74984881 | promoter | 3.07e-01 | 4.63e-01 | -3.33e+00 | 8.65e-04 | 2.02e-03 | -1.56e-01 |
Top |
Exon skipping events with PSI in TCGA for PI15 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PI15 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PI15 |
| TFs related to PI15. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| READ | ZNF264 | PI15 | 4.79e+00 | 9.92e-01 | 3.64e+00 | 2.77e-03 | Male-biased |
| READ | ZNF324B | PI15 | 4.80e+00 | 9.81e-01 | 4.06e+00 | 1.41e-02 | Male-biased |
| PI15 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PI15 |
| RBPs related to ES in PI15. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PI15 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000137558 | PCAT18,hsa-mir-206,PI15 | Tumor sex-biased ceRNA | TCGA-SARC |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs965417 | chr8:84035896:T:C | - | -0.108974538934339 | 0.0249363336759144 | HNSC | Female-baised eQTL |
| rs10103741 | chr8:84045185:C:T | - | -0.10605525987505 | 0.032591884792106 | HNSC | Female-baised eQTL |
| rs12056866 | chr8:84048457:A:G | - | -0.10605525987505 | 0.032591884792106 | HNSC | Female-baised eQTL |
| rs4529459 | chr8:84054135:C:T | - | -0.10605525987505 | 0.032591884792106 | HNSC | Female-baised eQTL |
| rs4298483 | chr8:84054165:C:T | - | -0.10605525987505 | 0.032591884792106 | HNSC | Female-baised eQTL |
| rs4529460 | chr8:84054346:C:T | - | -0.10605525987505 | 0.032591884792106 | HNSC | Female-baised eQTL |
| rs1156844 | chr8:84030331:A:G | - | -0.107072938913937 | 0.0327258370251517 | HNSC | Female-baised eQTL |
| rs12056684 | chr8:84048090:T:A | - | -0.106805604191722 | 0.0353503350960611 | HNSC | Female-baised eQTL |
| rs1442044 | chr8:84035170:A:G | - | -0.105135061618163 | 0.0387655487798651 | HNSC | Female-baised eQTL |
| rs10103764 | chr8:84015198:A:C | - | -0.110172623203231 | 0.0432026235671232 | HNSC | Female-baised eQTL |
| rs1372468 | chr8:84025777:G:A | - | -0.103431935633312 | 0.047393779596578 | HNSC | Female-baised eQTL |
| rs4739687 | chr8:84014228:G:A | - | -0.108546507781996 | 0.0498027268808675 | HNSC | Female-baised eQTL |
| rs73248008 | chr8:78624979:T:C | - | 0.11294330108399 | 0.0483758595366574 | LUSC | Female-baised eQTL |
| rs73248033 | chr8:78631917:C:T | - | 0.11294330108399 | 0.0483758595366574 | LUSC | Female-baised eQTL |
| rs117457223 | chr8:78635181:A:T | - | 0.11294330108399 | 0.0483758595366574 | LUSC | Female-baised eQTL |
| rs73246581 | chr8:78618045:G:A | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73246584 | chr8:78618483:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs113879534 | chr8:78618990:T:C | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73246592 | chr8:78620422:G:A | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73246593 | chr8:78621408:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73246595 | chr8:78622614:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs113040810 | chr8:78622694:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73246599 | chr8:78623016:A:G | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73246601 | chr8:78623450:T:G | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73248007 | chr8:78624762:T:C | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs79861824 | chr8:78625201:A:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73248009 | chr8:78625679:A:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs59881716 | chr8:78626613:G:A | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs58512111 | chr8:78626677:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73248017 | chr8:78629019:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs73248026 | chr8:78631637:C:T | - | 0.112754336038901 | 0.0496175412634853 | LUSC | Female-baised eQTL |
| rs7823073 | chr8:75099449:A:T | - | 0.0730709573564455 | 2.37390959678346e-06 | LUAD | Female-baised eQTL |
| rs17777937 | chr8:84025531:C:T | - | 0.0735009024857818 | 2.59367101632527e-06 | LUAD | Female-baised eQTL |
| rs201622748 | chr8:82391595:A:G | - | 0.0542964860460069 | 0.000345188400916341 | LUAD | Female-baised eQTL |
| rs199876554 | chr8:82322930:G:A | - | 0.0532689160026648 | 0.000412068076337012 | LUAD | Female-baised eQTL |
| rs78084426 | chr8:82328115:T:C | - | 0.0532689160026648 | 0.000412068076337012 | LUAD | Female-baised eQTL |
| rs79497919 | chr8:82329647:G:A | - | 0.0532689160026648 | 0.000412068076337012 | LUAD | Female-baised eQTL |
| rs117819235 | chr8:82330430:G:T | - | 0.0532689160026648 | 0.000412068076337012 | LUAD | Female-baised eQTL |
| rs7837725 | chr8:82898412:T:C | - | 0.0527151088287727 | 0.000451731594797775 | LUAD | Female-baised eQTL |
| rs75898517 | chr8:82251836:G:C | - | 0.0521084536167684 | 0.000523565762985272 | LUAD | Female-baised eQTL |
| rs77338481 | chr8:82256444:G:A | - | 0.0521084536167684 | 0.000523565762985272 | LUAD | Female-baised eQTL |
| rs75633176 | chr8:82262378:C:A | - | 0.0521084536167684 | 0.000523565762985272 | LUAD | Female-baised eQTL |
| rs79516583 | chr8:82307184:C:T | - | 0.05180928112525 | 0.000598186399594655 | LUAD | Female-baised eQTL |
| rs78092104 | chr8:82307944:A:G | - | 0.05180928112525 | 0.000598186399594655 | LUAD | Female-baised eQTL |
| rs114828208 | chr8:82218031:T:A | - | 0.0508619767663713 | 0.000704595734799197 | LUAD | Female-baised eQTL |
| rs78070102 | chr8:82181828:T:C | - | 0.0507027324347541 | 0.000761475887330951 | LUAD | Female-baised eQTL |
| rs77702699 | chr8:82294720:A:G | - | 0.0505720365077717 | 0.000803842982950523 | LUAD | Female-baised eQTL |
| rs78660901 | chr8:82301280:G:A | - | 0.0505720365077717 | 0.000803842982950523 | LUAD | Female-baised eQTL |
| rs79638504 | chr8:82301491:G:A | - | 0.0505720365077717 | 0.000803842982950523 | LUAD | Female-baised eQTL |
| rs78339965 | chr8:82207885:T:C | - | 0.0495990043267638 | 0.000962820708696202 | LUAD | Female-baised eQTL |
| rs79167307 | chr8:82221405:A:G | - | 0.0495990043267638 | 0.000962820708696202 | LUAD | Female-baised eQTL |
| rs79307608 | chr8:82225417:A:G | - | 0.0495990043267638 | 0.000962820708696202 | LUAD | Female-baised eQTL |
| rs74816106 | chr8:82228874:G:A | - | 0.0495990043267638 | 0.000962820708696202 | LUAD | Female-baised eQTL |
| rs77650298 | chr8:82228956:T:A | - | 0.0495990043267638 | 0.000962820708696202 | LUAD | Female-baised eQTL |
| rs148546991 | chr8:82229284:T:C | - | 0.0495990043267638 | 0.000962820708696202 | LUAD | Female-baised eQTL |
| rs76824855 | chr8:82184113:G:A | - | 0.0496015955115397 | 0.000965684122118484 | LUAD | Female-baised eQTL |
| rs148542216 | chr8:82192584:T:A | - | 0.0496015955115397 | 0.000965684122118484 | LUAD | Female-baised eQTL |
| rs116695901 | chr8:82192930:T:A | - | 0.0496015955115397 | 0.000965684122118484 | LUAD | Female-baised eQTL |
| rs78585086 | chr8:82200503:A:G | - | 0.0496015955115397 | 0.000965684122118484 | LUAD | Female-baised eQTL |
| rs75904981 | chr8:82201542:A:G | - | 0.0496015955115397 | 0.000965684122118484 | LUAD | Female-baised eQTL |
| rs79939752 | chr8:82246391:G:A | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs77198401 | chr8:82257903:C:T | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs80156584 | chr8:82270657:C:T | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs74532312 | chr8:82275265:A:T | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs145305245 | chr8:82276951:C:A | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs114168891 | chr8:82276983:A:G | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs79518952 | chr8:82282226:A:G | - | 0.0496008843440604 | 0.000965817631032982 | LUAD | Female-baised eQTL |
| rs751444 | chr8:82316883:A:T | - | 0.0472924337651106 | 0.00172389622251065 | LUAD | Female-baised eQTL |
| rs62513201 | chr8:82648253:C:G | - | 0.0472445740004019 | 0.00178830565197134 | LUAD | Female-baised eQTL |
| rs76677129 | chr8:82381535:A:G | - | 0.0470355338776279 | 0.00188668551594957 | LUAD | Female-baised eQTL |
| rs77499410 | chr8:82381257:G:A | - | 0.0459797812983132 | 0.00239556853439973 | LUAD | Female-baised eQTL |
| rs28791871 | chr8:71372766:A:T | - | 0.0447526994190969 | 0.00281073808341517 | LUAD | Female-baised eQTL |
| rs73286587 | chr8:82287724:C:T | - | 0.0451527046010306 | 0.00284742037266135 | LUAD | Female-baised eQTL |
| rs7816310 | chr8:71369969:C:T | - | 0.0447542245521337 | 0.0028554288160512 | LUAD | Female-baised eQTL |
| rs115486047 | chr8:82633425:G:C | - | 0.0451582466428154 | 0.00286627696390389 | LUAD | Female-baised eQTL |
| rs62514535 | chr8:82857166:T:G | - | 0.0436350495735387 | 0.0029344633377835 | LUAD | Female-baised eQTL |
| rs150508504 | chr8:82345427:C:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs79974676 | chr8:82346287:A:G | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs114641187 | chr8:82346566:T:C | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs76929670 | chr8:82347163:C:G | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs78194057 | chr8:82348339:A:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs116971760 | chr8:82349488:T:G | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs80235448 | chr8:82349561:C:A | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs78647859 | chr8:82354146:G:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs117505784 | chr8:82354181:T:A | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs78640751 | chr8:82355322:A:G | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs116222097 | chr8:82355555:C:G | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs117930743 | chr8:82355572:C:G | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs75562842 | chr8:82355723:C:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs115289714 | chr8:82355786:A:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs139965998 | chr8:82356081:C:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs191467901 | chr8:82356114:C:T | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs182796715 | chr8:82356153:T:A | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs79790484 | chr8:82356222:C:A | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs76374976 | chr8:82356258:G:A | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs76382573 | chr8:82356492:G:A | - | 0.0449989433370632 | 0.00297153617394109 | LUAD | Female-baised eQTL |
| rs78365840 | chr8:82356749:C:T | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs140616366 | chr8:82356868:A:G | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs74524503 | chr8:82356908:T:C | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs115555920 | chr8:82357043:C:T | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs76585245 | chr8:82357381:T:A | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs76015756 | chr8:82357747:C:G | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs115101560 | chr8:82363275:C:T | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs74979291 | chr8:82364445:G:A | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs78858126 | chr8:82366492:C:T | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs76548096 | chr8:82372481:C:T | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs180871609 | chr8:82375280:G:A | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs116689999 | chr8:82375537:T:C | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs114323689 | chr8:82375845:C:A | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs79422366 | chr8:82376525:G:C | - | 0.0449638498238688 | 0.00299872908895155 | LUAD | Female-baised eQTL |
| rs116101351 | chr8:82380611:T:C | - | 0.0449566707885617 | 0.00303361509026837 | LUAD | Female-baised eQTL |
| rs62513171 | chr8:82614327:G:C | - | 0.0443355194187208 | 0.00336338013624753 | LUAD | Female-baised eQTL |
| rs117993085 | chr8:82367158:C:T | - | 0.0439982654292258 | 0.00373433995301712 | LUAD | Female-baised eQTL |
| rs56137527 | chr8:84031823:C:T | - | 0.0436568508739716 | 0.0037542840352861 | LUAD | Female-baised eQTL |
| rs10098612 | chr8:77080074:A:G | - | 0.0421428078561382 | 0.00403193282448036 | LUAD | Female-baised eQTL |
| rs75832759 | chr8:82344128:A:G | - | 0.0427399304435113 | 0.00456745896519576 | LUAD | Female-baised eQTL |
| rs185031075 | chr8:82323036:T:C | - | 0.0425051080343974 | 0.00458777705188277 | LUAD | Female-baised eQTL |
| rs62527266 | chr8:84029952:C:T | - | 0.0419459210103566 | 0.00558292145364941 | LUAD | Female-baised eQTL |
| rs59294817 | chr8:84031204:C:A | - | 0.0419459210103566 | 0.00558292145364941 | LUAD | Female-baised eQTL |
| rs78466217 | chr8:84051848:C:T | - | 0.0419459210103566 | 0.00558292145364941 | LUAD | Female-baised eQTL |
| rs62527324 | chr8:84052275:T:C | - | 0.0419459210103566 | 0.00558292145364941 | LUAD | Female-baised eQTL |
| rs7839716 | chr8:71371211:T:C | - | 0.0412090849588606 | 0.00567684375283917 | LUAD | Female-baised eQTL |
| rs17777897 | chr8:84024025:G:A | - | 0.0414002536078604 | 0.00591465655358513 | LUAD | Female-baised eQTL |
| rs7008999 | chr8:82217322:G:T | - | 0.0416349148307786 | 0.00602176049234202 | LUAD | Female-baised eQTL |
| rs73284599 | chr8:82224326:A:G | - | 0.0416349148307786 | 0.00602176049234202 | LUAD | Female-baised eQTL |
| rs181014246 | chr8:82192461:A:C | - | 0.041638399344775 | 0.00604046999189936 | LUAD | Female-baised eQTL |
| rs16910676 | chr8:82617723:A:G | - | 0.0416259672755376 | 0.00622361112638633 | LUAD | Female-baised eQTL |
| rs881207 | chr8:84028370:A:G | - | 0.0411496070714635 | 0.00658218636370612 | LUAD | Female-baised eQTL |
| rs62527264 | chr8:84028920:A:G | - | 0.0411496070714635 | 0.00658218636370612 | LUAD | Female-baised eQTL |
| rs7821326 | chr8:71371200:A:G | - | 0.040453277345247 | 0.00669208713221074 | LUAD | Female-baised eQTL |
| rs11990758 | chr8:82222565:G:A | - | 0.0408580974814283 | 0.00705302720289188 | LUAD | Female-baised eQTL |
| rs73289844 | chr8:82344570:A:T | - | 0.0407525441694607 | 0.00744945601873766 | LUAD | Female-baised eQTL |
| rs9298394 | chr8:82820998:G:A | - | 0.0378270536893977 | 0.0107708465765857 | LUAD | Female-baised eQTL |
| rs28526775 | chr8:82317642:A:C | - | 0.0375268890231335 | 0.0128228261499339 | LUAD | Female-baised eQTL |
| rs6993334 | chr8:82318476:T:C | - | 0.0375268890231335 | 0.0128228261499339 | LUAD | Female-baised eQTL |
| rs2045975 | chr8:82319101:G:A | - | 0.0375268890231335 | 0.0128228261499339 | LUAD | Female-baised eQTL |
| rs6987592 | chr8:82324460:T:C | - | 0.0375268890231335 | 0.0128228261499339 | LUAD | Female-baised eQTL |
| rs11990911 | chr8:82328909:A:G | - | 0.0375268890231335 | 0.0128228261499339 | LUAD | Female-baised eQTL |
| rs11986488 | chr8:82336576:G:A | - | 0.0375268890231335 | 0.0128228261499339 | LUAD | Female-baised eQTL |
| rs7009326 | chr8:71370373:T:C | - | 0.0350852060335164 | 0.0145589974480519 | LUAD | Female-baised eQTL |
| rs79833565 | chr8:83894167:G:A | - | 0.0351018368962159 | 0.0193385171650373 | LUAD | Female-baised eQTL |
| rs1442048 | chr8:83895952:C:T | - | 0.0351033346673268 | 0.019410984512254 | LUAD | Female-baised eQTL |
| rs1866984 | chr8:83911456:C:T | - | -0.0350649651752991 | 0.0195808537472792 | LUAD | Female-baised eQTL |
| rs17446371 | chr8:77009160:A:G | - | 0.0342068484040826 | 0.0202479850191549 | LUAD | Female-baised eQTL |
| rs56758322 | chr8:83829142:T:A | - | 0.0341808307480043 | 0.0250013988705677 | LUAD | Female-baised eQTL |
| rs62507763 | chr8:77728160:G:A | - | 0.0338929466033406 | 0.0277995261938442 | LUAD | Female-baised eQTL |
| rs34332574 | chr8:78004703:T:C | - | 0.0335709436607656 | 0.0310457121907507 | LUAD | Female-baised eQTL |
| rs62507762 | chr8:77728099:G:A | - | 0.0328574096037322 | 0.0338749478191043 | LUAD | Female-baised eQTL |
| rs872922 | chr8:84027497:G:A | - | 0.0324272296311959 | 0.034456324959257 | LUAD | Female-baised eQTL |
| rs881209 | chr8:84028085:T:A | - | 0.0324272296311959 | 0.034456324959257 | LUAD | Female-baised eQTL |
| rs35134317 | chr8:78070821:T:C | - | 0.032605684838164 | 0.0365484722870676 | LUAD | Female-baised eQTL |
| rs13253458 | chr8:78057170:T:C | - | 0.0325779879073598 | 0.0368643677933449 | LUAD | Female-baised eQTL |
| rs199818185 | chr8:84016303:G:A | - | 0.0310902382169363 | 0.039859177795077 | LUAD | Female-baised eQTL |
| rs75526080 | chr8:84019720:G:A | - | 0.0310902382169363 | 0.039859177795077 | LUAD | Female-baised eQTL |
| rs7837017 | chr8:84023233:G:C | - | 0.0308936418540098 | 0.0486174163839612 | LUAD | Female-baised eQTL |
| rs6983443 | chr8:71341481:C:T | - | -0.0303196793311219 | 0.0491239568200002 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7827299 | chr8:71389681:C:T | - | -0.0357780252821955 | 0.0340444564384136 | HNSC | Male-baised eQTL |
| rs17759131 | chr8:70603020:C:T | - | 0.0465187999770878 | 0.0175403538281097 | LUSC | Male-baised eQTL |
| rs73685686 | chr8:70608680:T:C | - | 0.0465187999770878 | 0.0175403538281097 | LUSC | Male-baised eQTL |
| rs112131562 | chr8:70638919:T:C | - | 0.0474677937577888 | 0.0201523186505064 | LUSC | Male-baised eQTL |
| rs73685681 | chr8:70605083:A:T | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs73685682 | chr8:70605189:G:T | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs56344208 | chr8:70605255:A:T | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs56913577 | chr8:70606314:G:T | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs73685683 | chr8:70607180:T:A | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs73685684 | chr8:70607242:T:C | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs73685685 | chr8:70607379:G:A | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs111745460 | chr8:70607671:C:T | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs187470744 | chr8:70607729:A:C | - | 0.0453919111942681 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs146806989 | chr8:70631962:T:C | - | 0.0453724819795115 | 0.0298274962426104 | LUSC | Male-baised eQTL |
| rs17686482 | chr8:70610029:T:C | - | 0.0451962006268451 | 0.0315629912771179 | LUSC | Male-baised eQTL |
| rs117824485 | chr8:70630236:T:C | - | 0.0447889826063036 | 0.0357584018323525 | LUSC | Male-baised eQTL |
| rs73685693 | chr8:70634326:A:G | - | 0.0447889826063036 | 0.0357584018323525 | LUSC | Male-baised eQTL |
| rs78900611 | chr8:70635521:G:T | - | 0.0447889826063036 | 0.0357584018323525 | LUSC | Male-baised eQTL |
| rs113321444 | chr8:70639358:C:T | - | 0.0447889826063036 | 0.0357584018323525 | LUSC | Male-baised eQTL |
| rs138609091 | chr8:70639909:C:T | - | 0.0447889826063036 | 0.0357584018323525 | LUSC | Male-baised eQTL |
| rs56714105 | chr8:70640199:C:T | - | 0.0447889826063036 | 0.0357584018323525 | LUSC | Male-baised eQTL |
| rs17686770 | chr8:70634104:C:T | - | 0.044782308410682 | 0.035892268447315 | LUSC | Male-baised eQTL |
| rs111329004 | chr8:70643209:T:A | - | 0.0447657197731912 | 0.0359007753084747 | LUSC | Male-baised eQTL |
| rs58859533 | chr8:70644488:T:A | - | 0.0447657197731912 | 0.0359007753084747 | LUSC | Male-baised eQTL |
| rs76309240 | chr8:70647252:T:C | - | 0.0447657197731912 | 0.0359007753084747 | LUSC | Male-baised eQTL |
| rs73685694 | chr8:70648309:A:C | - | 0.0447657197731912 | 0.0359007753084747 | LUSC | Male-baised eQTL |
| rs73685688 | chr8:70612922:A:G | - | 0.0440740567413541 | 0.0392826265419071 | LUSC | Male-baised eQTL |
| rs73685689 | chr8:70613645:G:A | - | 0.0440740567413541 | 0.0392826265419071 | LUSC | Male-baised eQTL |
| rs79911644 | chr8:70625152:G:A | - | 0.0438563819257404 | 0.0417050691735963 | LUSC | Male-baised eQTL |
| rs76546502 | chr8:70625215:C:G | - | 0.0438563819257404 | 0.0417050691735963 | LUSC | Male-baised eQTL |
| rs142357997 | chr8:70630365:A:G | - | 0.0428980214627122 | 0.0497307462124922 | LUSC | Male-baised eQTL |
| rs76240267 | chr8:70632048:C:A | - | 0.0428980214627122 | 0.0497307462124922 | LUSC | Male-baised eQTL |
| rs11987678 | chr8:80316591:T:C | - | 0.0404628169537417 | 0.026280199728394 | LUAD | Male-baised eQTL |
| rs73267946 | chr8:68040345:C:T | - | 0.0389320962442942 | 0.0412394027645566 | LUAD | Male-baised eQTL |
| rs10096711 | chr8:68046469:C:A | - | 0.0389187963732878 | 0.0413882887165004 | LUAD | Male-baised eQTL |
| rs73267958 | chr8:68050385:G:A | - | 0.0389187963732878 | 0.0413882887165004 | LUAD | Male-baised eQTL |
| rs73267949 | chr8:68045626:G:A | - | 0.0388949461229497 | 0.0414310312850831 | LUAD | Male-baised eQTL |
| rs41358945 | chr8:68047247:T:C | - | 0.0388949461229497 | 0.0414310312850831 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000137558 |
| CpG Site: cg00128482 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: - | |
| Female Effect: -0.0547459050793475 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg00128482 | chr8:74825221 | gene,exon,promoter,UTR | -0.0547459050793475 | 7.02865984053723e-05 | -0.31932100178699885 | 1.876611058140228e-07 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of PI15 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
