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Gene: ENSG00000136068 |
Summary for FLNB |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000136068 | Gene symbol | FLNB |
| Gene name | filamin B | |
| HGNC | 3755 | |
| Entrez ID | 2317 | |
| Gene type | protein_coding | |
| Synonyms | FLNB|TAP|TABP|ABP-278|FH1 | |
| UniProtAcc | O75369 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for FLNB |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FLNB | 1.71e+04 | -1.21e+00 | 1.56e-01 | -7.76e+00 | 8.19e-15 | 7.95e-14 | COAD |
Top |
Sex-biased somatic mutation for FLNB |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for FLNB |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg23730027 | chr3:58009453 | CGI:chr3:58009194-58009491 | promoter,gene body | 2.86e-01 | 1.82e-01 | 2.03e+00 | 4.28e-02 | 4.71e-02 | 1.03e-01 |
| BRCA | cg17338821 | chr3:58010055 | CGI:chr3:58009194-58009491 | promoter,gene body | 3.76e-01 | 2.68e-01 | 3.24e+00 | 1.21e-03 | 1.05e-02 | 1.08e-01 |
| ACC | cg06029308 | chr3:58009342 | CGI:chr3:58009194-58009491 | promoter,gene body | 1.77e-01 | 3.25e-01 | -2.83e+00 | 4.64e-03 | 1.63e-02 | -1.48e-01 |
| ACC | cg15733367 | chr3:58009214 | CGI:chr3:58009194-58009491 | promoter,gene body | 7.18e-02 | 1.81e-01 | -3.00e+00 | 2.68e-03 | 1.13e-02 | -1.10e-01 |
| ACC | cg17338821 | chr3:58010055 | CGI:chr3:58009194-58009491 | promoter,gene body | 5.95e-01 | 7.17e-01 | -3.27e+00 | 1.06e-03 | 5.56e-03 | -1.22e-01 |
| ACC | cg23730027 | chr3:58009453 | CGI:chr3:58009194-58009491 | promoter,gene body | 3.87e-01 | 6.26e-01 | -3.32e+00 | 8.90e-04 | 4.80e-03 | -2.39e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg17338821 | chr3:58010055 | CGI:chr3:58009194-58009491 | promoter,gene body | 4.57e-01 | 3.44e-01 | 2.83e+00 | 4.69e-03 | 1.30e-02 | 1.13e-01 |
| BLCA | cg23730027 | chr3:58009453 | CGI:chr3:58009194-58009491 | promoter,gene body | 2.57e-01 | 3.72e-01 | -2.69e+00 | 7.17e-03 | 1.42e-02 | -1.15e-01 |
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Exon skipping events with PSI in TCGA for FLNB |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| HNSC | exon_skip_375622 | 6.84e-01 | 8.51e-01 | -4.32e+00 | 1.59e-05 | 1.52e-04 | -1.67e-01 |
| LUSC | exon_skip_375622 | 7.10e-01 | 8.12e-01 | -2.18e+00 | 2.94e-02 | 3.37e-02 | -1.02e-01 |
| ESCA | exon_skip_375622 | 7.62e-01 | 9.07e-01 | -2.25e+00 | 2.46e-02 | 3.58e-02 | -1.45e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| LIHC | exon_skip_375619 | 2.64e-01 | 1.42e-01 | 3.17e+00 | 1.54e-03 | 5.45e-03 | 1.23e-01 |
| READ | exon_skip_375619 | 1.37e-01 | 2.70e-01 | -2.21e+00 | 2.70e-02 | 3.69e-02 | -1.33e-01 |
| KICH | exon_skip_375622 | 9.47e-01 | 8.39e-01 | 3.76e+00 | 1.68e-04 | 1.73e-03 | 1.07e-01 |
Top |
RNA A-to-I editing events in TCGA for FLNB |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| KIRC | FLNB-009 | chr3_58156064_+ | 1.90e-01 | 1.77e-01 | 2.63e+00 | 8.56e-03 | 4.20e-02 | 1.34e-02 |
| THYM | FLNB-009 | chr3_58156064_+ | 1.80e-01 | 2.73e-01 | -2.37e+00 | 1.76e-02 | 4.73e-02 | -9.27e-02 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| HNSC | FLNB-009 | chr3_58156064_+ | 1.92e-01 | 1.40e-01 | 2.37e+00 | 1.77e-02 | 2.23e-02 | 5.18e-02 |
| LIHC | FLNB-009 | chr3_58156064_+ | 3.07e-01 | 2.24e-01 | 2.68e+00 | 7.26e-03 | 2.77e-02 | 8.37e-02 |
| KIRP | FLNB-009 | chr3_58156064_+ | 1.63e-01 | 1.38e-01 | 2.19e+00 | 2.82e-02 | 3.85e-02 | 2.55e-02 |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| BRCA | FLNB-009 | chr3_58156064_+ | 3.09e-01 | 1.68e-01 | 9.12e+00 | 7.56e-20 | 1.83e-18 | 1.41e-01 |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for FLNB |
| TFs related to FLNB. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| FLNB related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for FLNB |
| RBPs related to ES in FLNB. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | PCBP2 | exon_skip_375607 | 8.60e+00 | 9.89e-01 | 8.17e+00 | 4.88e-03 | Male-biased |
| STAD | SAMD4A | exon_skip_375613 | 7.20e+00 | 9.88e-01 | 6.41e+00 | 4.11e-04 | Male-biased |
| STAD | SAMD4A | exon_skip_375628 | 9.45e+00 | 9.97e-01 | 8.43e+00 | 9.24e-05 | Male-biased |
| ACC | MATR3 | exon_skip_375643 | 9.90e+00 | 1.14e-03 | 1.06e+01 | 9.98e-01 | Female-biased |
| THYM | IGF2BP1 | exon_skip_375635 | 8.20e+00 | 9.82e-01 | 7.88e+00 | 9.71e-03 | Male-biased |
| LIHC | SAMD4A | exon_skip_375628 | 9.13e+00 | 9.96e-01 | 8.03e+00 | 1.05e-04 | Male-biased |
| LUSC | BRUNOL6 | exon_skip_375632 | 8.41e+00 | 2.23e-03 | 8.92e+00 | 9.93e-01 | Female-biased |
| LUSC | PCBP2 | exon_skip_375607 | 8.54e+00 | 9.93e-01 | 7.90e+00 | 1.09e-03 | Male-biased |
| LUSC | SAMD4A | exon_skip_375628 | 9.18e+00 | 9.95e-01 | 8.55e+00 | 1.16e-03 | Male-biased |
| COAD | ZC3H10 | exon_skip_375635 | 7.85e+00 | 9.90e-01 | 7.29e+00 | 1.22e-03 | Male-biased |
| DLBC | BRUNOL6 | exon_skip_375632 | 8.54e+00 | 9.37e-03 | 8.89e+00 | 9.86e-01 | Female-biased |
| DLBC | MATR3 | exon_skip_375643 | 1.06e+01 | 9.97e-01 | 1.01e+01 | 2.13e-03 | Male-biased |
| LUAD | BRUNOL6 | exon_skip_375632 | 8.32e+00 | 3.04e-03 | 8.78e+00 | 9.92e-01 | Female-biased |
| LUAD | RBM6 | exon_skip_375612 | 9.93e+00 | 9.86e-01 | 9.62e+00 | 1.24e-02 | Male-biased |
| CHOL | MATR3 | exon_skip_375643 | 1.07e+01 | 9.89e-01 | 1.02e+01 | 9.52e-03 | Male-biased |
| CHOL | SAMD4A | exon_skip_375628 | 9.04e+00 | 9.93e-01 | 8.47e+00 | 2.71e-03 | Male-biased |
| KIRP | HNRNPA2B1 | exon_skip_375605 | 9.24e+00 | 1.08e-02 | 9.56e+00 | 9.86e-01 | Female-biased |
| KIRP | PCBP2 | exon_skip_375607 | 8.27e+00 | 9.80e-01 | 7.96e+00 | 1.22e-02 | Male-biased |
| KIRP | RBM6 | exon_skip_375612 | 9.62e+00 | 1.15e-02 | 9.94e+00 | 9.86e-01 | Female-biased |
| KIRP | SAMD4A | exon_skip_375613 | 5.97e+00 | 1.16e-04 | 6.75e+00 | 9.84e-01 | Female-biased |
| BRCA | PCBP2 | exon_skip_375607 | 7.80e+00 | 9.48e-03 | 8.46e+00 | 9.84e-01 | Female-biased |
| BRCA | SAMD4A | exon_skip_375613 | 6.24e+00 | 1.84e-03 | 7.42e+00 | 9.87e-01 | Female-biased |
| BRCA | SAMD4A | exon_skip_375628 | 8.05e+00 | 1.84e-04 | 1.02e+01 | 9.98e-01 | Female-biased |
| ESCA | IGF2BP2 | exon_skip_375601 | 8.37e+00 | 8.72e-03 | 8.83e+00 | 9.87e-01 | Female-biased |
| ESCA | IGF2BP3 | exon_skip_375601 | 8.34e+00 | 8.69e-03 | 8.79e+00 | 9.86e-01 | Female-biased |
| ESCA | PCBP2 | exon_skip_375607 | 8.35e+00 | 9.84e-01 | 7.89e+00 | 8.97e-03 | Male-biased |
| ESCA | SAMD4A | exon_skip_375628 | 9.40e+00 | 9.85e-01 | 8.99e+00 | 1.22e-02 | Male-biased |
| THCA | HNRNPA2B1 | exon_skip_375605 | 9.37e+00 | 9.93e-01 | 9.00e+00 | 3.77e-03 | Male-biased |
| MESO | BRUNOL6 | exon_skip_375632 | 8.47e+00 | 8.68e-03 | 8.83e+00 | 9.86e-01 | Female-biased |
| MESO | IGF2BP2 | exon_skip_375601 | 8.73e+00 | 1.36e-02 | 9.05e+00 | 9.82e-01 | Female-biased |
| MESO | IGF2BP3 | exon_skip_375601 | 8.69e+00 | 1.37e-02 | 9.01e+00 | 9.82e-01 | Female-biased |
| MESO | MATR3 | exon_skip_375643 | 1.01e+01 | 4.80e-03 | 1.05e+01 | 9.94e-01 | Female-biased |
| MESO | PCBP2 | exon_skip_375607 | 8.05e+00 | 9.94e-03 | 8.40e+00 | 9.83e-01 | Female-biased |
| MESO | SAMD4A | exon_skip_375613 | 6.61e+00 | 9.82e-01 | 6.02e+00 | 1.14e-03 | Male-biased |
| LGG | BRUNOL6 | exon_skip_375632 | 8.43e+00 | 6.52e-03 | 8.80e+00 | 9.88e-01 | Female-biased |
| LGG | IGF2BP1 | exon_skip_375635 | 7.89e+00 | 9.65e-03 | 8.23e+00 | 9.83e-01 | Female-biased |
| LGG | MATR3 | exon_skip_375643 | 1.03e+01 | 9.91e-01 | 9.98e+00 | 7.71e-03 | Male-biased |
| LGG | ZC3H10 | exon_skip_375635 | 6.96e+00 | 1.66e-03 | 7.46e+00 | 9.88e-01 | Female-biased |
| PAAD | BRUNOL6 | exon_skip_375632 | 8.29e+00 | 9.88e-03 | 8.59e+00 | 9.84e-01 | Female-biased |
| PAAD | SAMD4A | exon_skip_375613 | 6.47e+00 | 9.81e-01 | 5.95e+00 | 6.56e-04 | Male-biased |
| PAAD | ZC3H10 | exon_skip_375635 | 7.45e+00 | 9.86e-01 | 7.06e+00 | 3.03e-03 | Male-biased |
| KIRC | PCBP2 | exon_skip_375607 | 8.07e+00 | 3.97e-03 | 8.47e+00 | 9.90e-01 | Female-biased |
| SKCM | HNRNPA2B1 | exon_skip_375605 | 8.97e+00 | 1.18e-02 | 9.31e+00 | 9.85e-01 | Female-biased |
| SKCM | SAMD4A | exon_skip_375628 | 8.75e+00 | 1.21e-02 | 9.08e+00 | 9.84e-01 | Female-biased |
| SARC | PCBP2 | exon_skip_375607 | 8.22e+00 | 5.34e-03 | 8.65e+00 | 9.89e-01 | Female-biased |
| SARC | ZC3H10 | exon_skip_375635 | 7.81e+00 | 9.88e-01 | 7.31e+00 | 3.05e-03 | Male-biased |
| FLNB related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs139602097 | chr3:59399173:G:A | - | 0.135229725335132 | 0.0358598377350764 | HNSC | Female-baised eQTL |
| rs55860221 | chr3:59421789:G:T | - | 0.119909121213953 | 0.0486633200365141 | HNSC | Female-baised eQTL |
| rs73128657 | chr3:64269273:C:T | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128658 | chr3:64270059:G:A | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128665 | chr3:64270515:T:A | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128672 | chr3:64277017:G:A | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128673 | chr3:64277634:C:T | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128678 | chr3:64283276:A:G | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128679 | chr3:64283548:T:C | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs17404257 | chr3:64285247:T:C | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs17344849 | chr3:64286159:T:A | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs17404529 | chr3:64287421:T:C | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs17404667 | chr3:64288876:C:G | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs17404744 | chr3:64290236:C:T | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs73128685 | chr3:64296997:A:G | - | 0.434955337351287 | 0.0423860970825399 | GBM | Female-baised eQTL |
| rs17404898 | chr3:64293782:T:C | - | 0.435138065461372 | 0.0424245102501444 | GBM | Female-baised eQTL |
| rs11926187 | chr3:64278150:T:G | - | 0.433927733511832 | 0.0438897608586991 | GBM | Female-baised eQTL |
| rs115433431 | chr3:64275056:C:G | - | 0.433916127225766 | 0.0445629069685769 | GBM | Female-baised eQTL |
| rs116579203 | chr3:64278302:A:G | - | 0.433214349842384 | 0.0452834300970548 | GBM | Female-baised eQTL |
| rs144516708 | chr3:65065303:G:T | - | 0.18199743185045 | 0.0128601490321702 | LIHC | Female-baised eQTL |
| rs6765763 | chr3:65066760:G:T | - | 0.159449296731504 | 0.0450916333619072 | LIHC | Female-baised eQTL |
| rs73120404 | chr3:65073566:A:T | - | 0.155691517339594 | 0.0457217387031166 | LIHC | Female-baised eQTL |
| rs1482598 | chr3:65077492:C:T | - | 0.155691517339594 | 0.0457217387031166 | LIHC | Female-baised eQTL |
| rs2226972 | chr3:60602362:A:G | - | 0.0584341694543092 | 0.0191618823109834 | LUAD | Female-baised eQTL |
| rs4289378 | chr3:51143348:T:C | - | -0.110549997806038 | 0.0293992782219063 | COAD | Female-baised eQTL |
| rs7653147 | chr3:57448289:G:A | - | 0.110197329898773 | 0.0346377946953932 | COAD | Female-baised eQTL |
| rs6767731 | chr3:57450011:G:T | - | 0.110197329898773 | 0.0346377946953932 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs55671636 | chr3:64252775:G:C | - | 0.104055171564842 | 0.0180778236224258 | GBM | Male-baised eQTL |
| rs34908451 | chr3:52351099:C:T | - | 0.054616449266004 | 0.0217074202968823 | BLCA | Male-baised eQTL |
| rs34762015 | chr3:52332028:G:A | - | 0.0541706706924115 | 0.0227983995486449 | BLCA | Male-baised eQTL |
| rs2335640 | chr3:52334371:T:C | - | 0.0541706706924115 | 0.0227983995486449 | BLCA | Male-baised eQTL |
| rs56357549 | chr3:52340500:T:G | - | 0.0541664901057987 | 0.0229670063791092 | BLCA | Male-baised eQTL |
| rs11707931 | chr3:52324401:C:G | - | 0.0532598677848557 | 0.0277746929287719 | BLCA | Male-baised eQTL |
| rs35133416 | chr3:52325024:C:T | - | 0.0532598677848557 | 0.0277746929287719 | BLCA | Male-baised eQTL |
| rs6763882 | chr3:52320756:C:T | - | 0.0529446503794493 | 0.0289137292887612 | BLCA | Male-baised eQTL |
| rs17052068 | chr3:52318848:C:T | - | 0.0528230398022648 | 0.0294688374399023 | BLCA | Male-baised eQTL |
| rs11716017 | chr3:52346975:C:T | - | 0.0542018434730466 | 0.030841617505893 | BLCA | Male-baised eQTL |
| rs34355561 | chr3:52349104:G:A | - | 0.0542018434730466 | 0.030841617505893 | BLCA | Male-baised eQTL |
| rs11707864 | chr3:52358861:G:A | - | 0.0542018434730466 | 0.030841617505893 | BLCA | Male-baised eQTL |
| rs13075370 | chr3:52365262:G:A | - | 0.0542018434730466 | 0.030841617505893 | BLCA | Male-baised eQTL |
| rs11709658 | chr3:52365611:G:A | - | 0.0542018434730466 | 0.030841617505893 | BLCA | Male-baised eQTL |
| rs3752819 | chr3:52366724:G:C | - | 0.0542018434730466 | 0.030841617505893 | BLCA | Male-baised eQTL |
| rs111593386 | chr3:52312714:G:T | - | 0.0521619176981232 | 0.0323613978115009 | BLCA | Male-baised eQTL |
| rs61150019 | chr3:52320360:G:A | - | 0.0523741803412898 | 0.0346425037404806 | BLCA | Male-baised eQTL |
| rs67834575 | chr3:52377913:T:A | - | 0.0518151416723151 | 0.0356235013873892 | BLCA | Male-baised eQTL |
| rs67248391 | chr3:52377990:A:T | - | 0.0518151416723151 | 0.0356235013873892 | BLCA | Male-baised eQTL |
| rs11705963 | chr3:52337975:T:G | - | 0.0477317067883822 | 0.0372967844411597 | BLCA | Male-baised eQTL |
| rs11706108 | chr3:52338350:T:C | - | 0.0477317067883822 | 0.0372967844411597 | BLCA | Male-baised eQTL |
| rs35860312 | chr3:52353062:T:C | - | 0.0463425630598091 | 0.0429851081699847 | BLCA | Male-baised eQTL |
| rs11718125 | chr3:52345404:T:C | - | 0.0502688210678642 | 0.0444160443967209 | BLCA | Male-baised eQTL |
| rs7643570 | chr3:52339776:G:T | - | 0.0474418111048757 | 0.0462360696573621 | BLCA | Male-baised eQTL |
| rs13091545 | chr3:52343278:A:G | - | 0.0474418111048757 | 0.0462360696573621 | BLCA | Male-baised eQTL |
| rs59612757 | chr3:52265505:T:C | - | 0.0488351550000213 | 0.0462417544881102 | BLCA | Male-baised eQTL |
| rs11714402 | chr3:52357719:A:C | - | 0.0497280754626275 | 0.0472354376127514 | BLCA | Male-baised eQTL |
| rs34238085 | chr3:52334931:A:C | - | 0.0493748277993771 | 0.0484923424816292 | BLCA | Male-baised eQTL |
| rs17052058 | chr3:52310664:A:G | - | 0.0491901561994245 | 0.0487255494564465 | BLCA | Male-baised eQTL |
| rs13059674 | chr3:52337773:T:G | - | 0.0493674556650947 | 0.0488124698822508 | BLCA | Male-baised eQTL |
| rs34523877 | chr3:52341695:T:C | - | 0.0493674556650947 | 0.0488124698822508 | BLCA | Male-baised eQTL |
| rs268765 | chr3:57920697:A:G | - | 0.0900527557347915 | 0.00807757077825524 | LUAD | Male-baised eQTL |
| rs113858024 | chr3:57775192:T:C | - | 0.0854736863621726 | 0.0121619780028386 | LUAD | Male-baised eQTL |
| rs4273341 | chr3:57892231:T:C | - | 0.0862352413437106 | 0.0122369273712493 | LUAD | Male-baised eQTL |
| rs266838 | chr3:57819545:A:C | - | 0.0841498275161975 | 0.0122401229025013 | LUAD | Male-baised eQTL |
| rs266837 | chr3:57820559:C:T | - | 0.0841498275161975 | 0.0122401229025013 | LUAD | Male-baised eQTL |
| rs11130601 | chr3:57823156:G:A | - | 0.0841498275161975 | 0.0122401229025013 | LUAD | Male-baised eQTL |
| rs6779436 | chr3:57829857:G:A | - | 0.0841498275161975 | 0.0122401229025013 | LUAD | Male-baised eQTL |
| rs79810718 | chr3:57830425:C:T | - | 0.0841498275161975 | 0.0122401229025013 | LUAD | Male-baised eQTL |
| rs6779308 | chr3:57833391:A:G | - | 0.0841498275161975 | 0.0122401229025013 | LUAD | Male-baised eQTL |
| rs17058647 | chr3:57899336:C:T | - | 0.0856828378047418 | 0.0126865152925644 | LUAD | Male-baised eQTL |
| rs12497570 | chr3:57894193:T:C | - | 0.0855211823976725 | 0.0132572625605664 | LUAD | Male-baised eQTL |
| rs9311662 | chr3:57866163:G:C | - | -0.0857621550876041 | 0.0135041864040831 | LUAD | Male-baised eQTL |
| rs141780045 | chr3:57873891:C:T | - | 0.085762155087604 | 0.0135041864040831 | LUAD | Male-baised eQTL |
| rs79353264 | chr3:57880775:C:T | - | 0.085762155087604 | 0.0135041864040831 | LUAD | Male-baised eQTL |
| rs34918206 | chr3:57785033:A:G | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs266844 | chr3:57798112:T:C | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs266843 | chr3:57799387:T:A | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs266842 | chr3:57800930:A:G | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs266841 | chr3:57806170:A:G | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs266840 | chr3:57806530:C:T | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs266839 | chr3:57808726:A:G | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs2601127 | chr3:57809572:G:A | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs1670043 | chr3:57810450:G:A | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs1670049 | chr3:57812697:G:A | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs182055 | chr3:57816444:G:A | - | 0.0824065883255546 | 0.0157542683007688 | LUAD | Male-baised eQTL |
| rs78930913 | chr3:57848604:C:T | - | 0.084871392990714 | 0.0158566845750051 | LUAD | Male-baised eQTL |
| rs111382871 | chr3:57850752:G:C | - | 0.084871392990714 | 0.0158566845750051 | LUAD | Male-baised eQTL |
| rs12487033 | chr3:57851221:T:C | - | 0.084871392990714 | 0.0158566845750051 | LUAD | Male-baised eQTL |
| rs35607252 | chr3:57851639:A:T | - | 0.084871392990714 | 0.0158566845750051 | LUAD | Male-baised eQTL |
| rs6762298 | chr3:57852748:A:G | - | 0.084871392990714 | 0.0158566845750051 | LUAD | Male-baised eQTL |
| rs2361351 | chr3:57861796:T:C | - | 0.084871392990714 | 0.0158566845750051 | LUAD | Male-baised eQTL |
| rs78568209 | chr3:57779494:G:C | - | 0.0822727777667549 | 0.0163285214758405 | LUAD | Male-baised eQTL |
| rs78862612 | chr3:57781894:A:G | - | 0.0807186539206258 | 0.0201420127145527 | LUAD | Male-baised eQTL |
| rs202036837 | chr3:57609066:G:T | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs62258963 | chr3:57613362:C:T | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs11713689 | chr3:57615855:G:A | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs11706647 | chr3:57615995:A:T | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs12495484 | chr3:57619777:G:A | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs62258964 | chr3:57621978:G:A | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs11130594 | chr3:57631316:T:C | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs62258965 | chr3:57634051:A:T | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs62258967 | chr3:57638677:A:C | - | 0.0786988971796489 | 0.0204616343062946 | LUAD | Male-baised eQTL |
| rs73102754 | chr3:62815941:C:A | - | 0.0881399091122485 | 0.0210193773695938 | LUAD | Male-baised eQTL |
| rs34283300 | chr3:57676930:T:A | - | 0.0770196829946759 | 0.0214653172684938 | LUAD | Male-baised eQTL |
| rs11713195 | chr3:57597790:A:G | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs4638933 | chr3:57599679:G:A | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs6809883 | chr3:57600697:C:T | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs12488541 | chr3:57601232:C:T | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs12639257 | chr3:57602818:G:A | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs12633848 | chr3:57602854:A:C | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs62258962 | chr3:57605526:T:C | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs4402904 | chr3:57605655:T:C | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs111740689 | chr3:57607495:A:C | - | 0.0778348689115143 | 0.0238713245557552 | LUAD | Male-baised eQTL |
| rs77340367 | chr3:57767780:G:A | - | 0.0805555887632782 | 0.0247656547298105 | LUAD | Male-baised eQTL |
| rs34529112 | chr3:57781467:C:T | - | 0.0793103198241127 | 0.0250334183008275 | LUAD | Male-baised eQTL |
| rs7619066 | chr3:57539435:C:T | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs6445909 | chr3:57541042:T:C | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs4681997 | chr3:57541200:A:G | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs11710515 | chr3:57542488:C:T | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs7614741 | chr3:57545044:G:C | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs6445910 | chr3:57546921:A:G | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs7610386 | chr3:57548700:G:T | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs4681735 | chr3:57549089:A:G | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs6445911 | chr3:57551745:A:T | - | -0.0777848414525908 | 0.0263373586361685 | LUAD | Male-baised eQTL |
| rs73102752 | chr3:62815730:T:C | - | 0.0860182919950402 | 0.0272559312022377 | LUAD | Male-baised eQTL |
| rs2306056 | chr3:57860850:C:A | - | 0.0814920758066003 | 0.0273550456676818 | LUAD | Male-baised eQTL |
| rs6779410 | chr3:57576967:T:C | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs201004494 | chr3:57582719:T:C | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs11130591 | chr3:57582856:C:T | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs11130592 | chr3:57585237:T:G | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs62260505 | chr3:57588297:A:G | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs12630440 | chr3:57589554:C:T | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs62260506 | chr3:57590684:A:G | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs11130593 | chr3:57593117:T:C | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs11707134 | chr3:57595123:T:C | - | 0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs9311653 | chr3:57555058:A:C | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs4681999 | chr3:57559114:C:G | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs11130589 | chr3:57563501:A:T | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs7643904 | chr3:57564819:G:A | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs7637016 | chr3:57565818:A:T | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs7627159 | chr3:57568313:A:G | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs9311654 | chr3:57571102:T:C | - | -0.0768949627573517 | 0.0291021299664987 | LUAD | Male-baised eQTL |
| rs13400 | chr3:57757610:C:G | - | 0.0776930054958248 | 0.0305816993816375 | LUAD | Male-baised eQTL |
| rs113502120 | chr3:57589713:G:A | - | 0.0765438837966009 | 0.0311281990910231 | LUAD | Male-baised eQTL |
| rs12492169 | chr3:57911812:G:A | - | 0.0804450667221451 | 0.0311481582773877 | LUAD | Male-baised eQTL |
| rs77811323 | chr3:53764014:G:A | - | 0.107362505280215 | 0.0327690730877764 | LUAD | Male-baised eQTL |
| rs4681754 | chr3:57729965:G:A | - | 0.0765105958339743 | 0.0355979594523351 | LUAD | Male-baised eQTL |
| rs1452376 | chr3:57721805:G:A | - | 0.075009016736147 | 0.0359884604003007 | LUAD | Male-baised eQTL |
| rs4681741 | chr3:57648621:G:A | - | 0.0751182164178135 | 0.0362310493175789 | LUAD | Male-baised eQTL |
| rs11708586 | chr3:57651352:T:C | - | 0.0751182164178135 | 0.0362310493175789 | LUAD | Male-baised eQTL |
| rs11708662 | chr3:57651567:T:C | - | 0.0751182164178135 | 0.0362310493175789 | LUAD | Male-baised eQTL |
| rs35824879 | chr3:57652657:T:C | - | 0.0751182164178135 | 0.0362310493175789 | LUAD | Male-baised eQTL |
| rs2060852 | chr3:57739198:A:G | - | 0.0762527154291283 | 0.0374674113075915 | LUAD | Male-baised eQTL |
| rs12635621 | chr3:57717310:G:A | - | 0.074855687249103 | 0.0379234405437905 | LUAD | Male-baised eQTL |
| rs75127895 | chr3:57718986:A:T | - | 0.0737330389161925 | 0.0420671246433552 | LUAD | Male-baised eQTL |
| rs74330651 | chr3:57718987:A:T | - | 0.0737330389161925 | 0.0420671246433552 | LUAD | Male-baised eQTL |
| rs4681744 | chr3:57694381:T:C | - | 0.0740106597837595 | 0.0425721810211759 | LUAD | Male-baised eQTL |
| rs2123206 | chr3:57696486:G:A | - | 0.0740106597837595 | 0.0425721810211759 | LUAD | Male-baised eQTL |
| rs2060851 | chr3:57702630:G:A | - | 0.0740106597837595 | 0.0425721810211759 | LUAD | Male-baised eQTL |
| rs12497332 | chr3:57702643:C:T | - | 0.0740106597837595 | 0.0425721810211759 | LUAD | Male-baised eQTL |
| rs13089228 | chr3:57708351:G:A | - | 0.0740106597837595 | 0.0425721810211759 | LUAD | Male-baised eQTL |
| rs4681750 | chr3:57708880:C:T | - | 0.0740106597837595 | 0.0425721810211759 | LUAD | Male-baised eQTL |
| rs200613467 | chr3:57699019:A:C | - | 0.0739450551732247 | 0.0434539668939056 | LUAD | Male-baised eQTL |
| rs62250897 | chr3:53767557:C:A | - | 0.103648027878296 | 0.0439022835790651 | LUAD | Male-baised eQTL |
| rs11718944 | chr3:57680232:G:C | - | 0.0737077840610418 | 0.0440243456933123 | LUAD | Male-baised eQTL |
| rs11130596 | chr3:57668142:A:G | - | 0.0734462060076323 | 0.0453124131275947 | LUAD | Male-baised eQTL |
| rs35161449 | chr3:57669014:G:A | - | 0.0734462060076323 | 0.0453124131275947 | LUAD | Male-baised eQTL |
| rs34710625 | chr3:57677577:A:C | - | 0.0734462060076323 | 0.0453124131275947 | LUAD | Male-baised eQTL |
| rs12636563 | chr3:57678250:G:C | - | 0.0734462060076323 | 0.0453124131275947 | LUAD | Male-baised eQTL |
| rs4434122 | chr3:57685289:A:T | - | 0.0734462060076323 | 0.0453124131275947 | LUAD | Male-baised eQTL |
| rs12629424 | chr3:57688456:C:A | - | 0.0734462060076323 | 0.0453124131275947 | LUAD | Male-baised eQTL |
| rs266845 | chr3:57793943:T:G | - | 0.0773899868567732 | 0.0491003726151008 | LUAD | Male-baised eQTL |
| rs78827010 | chr3:58620531:C:T | - | 0.12073056364621 | 0.00155605616511852 | COAD | Male-baised eQTL |
| rs11130659 | chr3:58621668:G:A | - | 0.120424884463111 | 0.00162963003625751 | COAD | Male-baised eQTL |
| rs11707902 | chr3:58622378:T:A | - | 0.0958870193572889 | 0.00662612091404285 | COAD | Male-baised eQTL |
| rs11708342 | chr3:58626871:C:T | - | 0.0871953119524459 | 0.0160246989376327 | COAD | Male-baised eQTL |
| rs115038457 | chr3:64777538:G:A | - | 0.0708069096782411 | 0.0172088020523762 | COAD | Male-baised eQTL |
| rs36188862 | chr3:64778782:G:A | - | 0.0708069096782411 | 0.0172088020523762 | COAD | Male-baised eQTL |
| rs114104475 | chr3:64780210:A:G | - | 0.0708069096782411 | 0.0172088020523762 | COAD | Male-baised eQTL |
| rs114640626 | chr3:64780563:A:G | - | 0.0708069096782411 | 0.0172088020523762 | COAD | Male-baised eQTL |
| rs145260039 | chr3:64780586:C:T | - | 0.0708069096782411 | 0.0172088020523762 | COAD | Male-baised eQTL |
| rs6797091 | chr3:64768152:A:G | - | 0.0706061522471541 | 0.0181402617128582 | COAD | Male-baised eQTL |
| rs34848722 | chr3:64783025:G:A | - | 0.0694442427557975 | 0.0196070773116285 | COAD | Male-baised eQTL |
| rs35168143 | chr3:64798503:C:T | - | 0.0694704923343346 | 0.021314084371481 | COAD | Male-baised eQTL |
| rs34494622 | chr3:64799634:A:G | - | 0.0694704923343346 | 0.021314084371481 | COAD | Male-baised eQTL |
| rs56374410 | chr3:64799641:C:T | - | 0.0694704923343346 | 0.021314084371481 | COAD | Male-baised eQTL |
| rs13076552 | chr3:64763326:C:T | - | 0.0707853218597899 | 0.0223733408010273 | COAD | Male-baised eQTL |
| rs9818204 | chr3:64765696:T:C | - | 0.0668354051561133 | 0.0227703418979876 | COAD | Male-baised eQTL |
| rs34827027 | chr3:64766035:C:T | - | 0.0668354051561133 | 0.0227703418979876 | COAD | Male-baised eQTL |
| rs2687899 | chr3:59985232:C:T | - | 0.0442489089608531 | 0.0228545736066268 | COAD | Male-baised eQTL |
| rs73104986 | chr3:62567464:G:A | - | 0.0913922251031161 | 0.0228781234374968 | COAD | Male-baised eQTL |
| rs13099672 | chr3:64749679:G:T | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs142593669 | chr3:64752489:G:T | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs13085468 | chr3:64752788:A:G | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs34118601 | chr3:64754653:A:G | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs34115644 | chr3:64762240:G:C | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs34364609 | chr3:64763971:C:A | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs71300727 | chr3:64764408:C:T | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs34422895 | chr3:64765040:A:C | - | 0.0704506481576462 | 0.0234082323249934 | COAD | Male-baised eQTL |
| rs802772 | chr3:59981249:T:A | - | 0.0423395995101144 | 0.0268819170201995 | COAD | Male-baised eQTL |
| rs10866028 | chr3:59321350:G:T | - | 0.0484447178887021 | 0.0309903113336754 | COAD | Male-baised eQTL |
| rs802774 | chr3:59981947:G:A | - | 0.041843295295433 | 0.0316980363019781 | COAD | Male-baised eQTL |
| rs73091970 | chr3:59321716:G:T | - | 0.0492891699771031 | 0.0414385215791331 | COAD | Male-baised eQTL |
| rs28377515 | chr3:62506114:G:A | - | 0.0862818510003802 | 0.042337441257366 | COAD | Male-baised eQTL |
| rs73101300 | chr3:62514791:T:G | - | 0.0825792790839217 | 0.0468706964341783 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000136068 |
| CpG Site: cg05093811 | |
| Position to Gene: gene | |
| Male Effect: -0.446403171428138 | |
| Female Effect: - | |
 | Gene ID: ENSG00000136068 |
| CpG Site: cg12194336 | |
| Position to Gene: gene | |
| Male Effect: -0.446403171428138 | |
| Female Effect: - | |
 | Gene ID: ENSG00000136068 |
| CpG Site: cg03479209 | |
| Position to Gene: gene | |
| Male Effect: -0.162317896903788 | |
| Female Effect: - | |
 | Gene ID: ENSG00000136068 |
| CpG Site: cg26295272 | |
| Position to Gene: gene | |
| Male Effect: -0.197882785784207 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg05093811 | chr3:58074192 | gene | -0.446403171428138 | 7.63820048128505e-28 | -0.6997839391166726 | 6.817592872933416e-31 | KIRP |
| cg12194336 | chr3:58082179 | gene | -0.446403171428138 | 7.63820048128505e-28 | -0.6997839391166726 | 6.817592872933416e-31 | KIRP |
| cg03479209 | chr3:58035272 | gene | -0.162317896903788 | 3.285848991151e-08 | -0.43445522828749045 | 1.1641384465907585e-10 | KIRP |
| cg26295272 | chr3:58059613 | gene | -0.197882785784207 | 5.66944013996175e-05 | -0.3364917912008127 | 1.1777161614654364e-06 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs34001924 | chr3:58617010:G:A | Distant downstream | -0.0878332059649566 | 0.000255045278365464 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11719674 | chr3:58617052:G:A | Distant downstream | -0.0878332059649566 | 0.000255045278365464 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs17059501 | chr3:58617884:C:T | Distant downstream | -0.0878332059649566 | 0.000255045278365464 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11708352 | chr3:58626758:G:A | Distant downstream | -0.0711650108074416 | 0.00339587970979766 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11708342 | chr3:58626871:C:T | Distant downstream | -0.0682786441863144 | 0.00490736935845449 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11130662 | chr3:58633125:A:C | Distant downstream | -0.0550683253024564 | 0.00553764427717995 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11130661 | chr3:58633037:A:G | Distant downstream | -0.0577344557500604 | 0.00633518842910297 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11130663 | chr3:58633446:T:G | Distant downstream | -0.0559438816900682 | 0.00899801083197827 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9862897 | chr3:58630900:T:C | Distant downstream | 0.056823454286436 | 0.0165288726318916 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs72876195 | chr3:58631338:A:G | Distant downstream | -0.05399278680055 | 0.0167905846373098 | KIRC | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11706920 | chr3:58293945:C:T | Distant downstream | -0.162282774318213 | 0.000504610415590122 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs28659863 | chr3:58342345:C:T | Distant downstream | -0.164115969423568 | 0.0173806264173044 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11717417 | chr3:58374364:G:A | Distant downstream | -0.156513893483273 | 0.0197504198040826 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11720747 | chr3:58282106:G:A | Distant downstream | -0.157258272143669 | 0.0202128762874662 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs17059098 | chr3:58270012:G:A | Distant downstream | -0.146810073838338 | 0.0235601498958121 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9862969 | chr3:58356190:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs35225811 | chr3:58359480:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs75828026 | chr3:58361009:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9850717 | chr3:58366148:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9819072 | chr3:58367920:A:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9860970 | chr3:58368054:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs34987857 | chr3:58373279:T:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs12330155 | chr3:58378815:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs12330157 | chr3:58378835:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs36097398 | chr3:58381603:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13096020 | chr3:58382044:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9846990 | chr3:58383233:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311864 | chr3:58386597:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311865 | chr3:58386696:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs28417694 | chr3:58388212:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9879870 | chr3:58389848:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13315871 | chr3:58395560:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11710058 | chr3:58397321:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13317835 | chr3:58397548:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4560319 | chr3:58400547:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4367085 | chr3:58403508:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9844128 | chr3:58405400:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9844432 | chr3:58405566:C:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11706420 | chr3:58406684:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311868 | chr3:58407147:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9864824 | chr3:58409108:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13071688 | chr3:58413003:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311869 | chr3:58413195:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311870 | chr3:58413556:T:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9869276 | chr3:58415349:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9869576 | chr3:58415535:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9869940 | chr3:58415796:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs28709068 | chr3:58419473:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9825431 | chr3:58420967:G:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13327709 | chr3:58423040:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13317400 | chr3:58423065:T:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13320620 | chr3:58423118:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs3196769 | chr3:58423634:A:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs28626602 | chr3:58424059:G:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13063504 | chr3:58424127:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4075404 | chr3:58425692:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4075403 | chr3:58425718:G:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs1131052 | chr3:58425803:A:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11719957 | chr3:58429304:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4585221 | chr3:58429840:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4519721 | chr3:58435611:C:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9811074 | chr3:58436119:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9849482 | chr3:58436360:G:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs34161601 | chr3:58440024:G:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13066409 | chr3:58442717:A:G | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs11716012 | chr3:58443479:G:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs4362735 | chr3:58444166:G:C | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13078787 | chr3:58444760:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs9824965 | chr3:58447778:T:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13076951 | chr3:58450976:C:T | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs28489489 | chr3:58458028:C:A | Distant downstream | -0.14884452482813 | 0.0278886199660829 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311854 | chr3:58333432:G:A | Distant downstream | -0.142892754702939 | 0.0455465546690771 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs71311856 | chr3:58337588:G:A | Distant downstream | -0.142892754702939 | 0.0455465546690771 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13067940 | chr3:58349483:G:C | Distant downstream | -0.142892754702939 | 0.0455465546690771 | BLCA | Female-baised sQTL |
| exon_skip_375623 | chr3:58141857:58141929 | In-frame | rs13060489 | chr3:58353560:G:A | Distant downstream | -0.152770116933197 | 0.0456236073420292 | BLCA | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of FLNB |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000136068 | FLNB | C0265283 | Atelosteogenesis, type 1 | 1 | CTD_human |
| ENSG00000136068 | FLNB | C0432201 | Boomerang dysplasia | 1 | CTD_human |
| ENSG00000136068 | FLNB | C1848934 | SPONDYLOCARPOTARSAL SYNOSTOSIS SYNDROME | 1 | CTD_human |
| ENSG00000136068 | FLNB | C2931648 | Larsen syndrome, dominant type | 1 | CTD_human |
| ENSG00000136068 | FLNB | C3668942 | Atelosteogenesis Type 3 | 1 | CTD_human |
