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Gene: ENSG00000135926 |
Summary for TMBIM1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000135926 | Gene symbol | TMBIM1 |
| Gene name | transmembrane BAX inhibitor motif containing 1 | |
| HGNC | 23410 | |
| Entrez ID | 64114 | |
| Gene type | protein_coding | |
| Synonyms | TMBIM1|PP1201|RECS1|LFG3 | |
| UniProtAcc | Q969X1 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TMBIM1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TMBIM1 | 8.87e+03 | -1.12e+00 | 6.18e-02 | -1.81e+01 | 2.30e-73 | 4.52e-72 | BRCA |
Top |
Sex-biased somatic mutation for TMBIM1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for TMBIM1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg25353281 | chr2:218290655 | CGI:chr2:218292254-218292657 | promoter,gene body | 6.74e-01 | 8.39e-01 | -3.04e+00 | 2.33e-03 | 1.47e-02 | -1.65e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg25353281 | chr2:218290655 | CGI:chr2:218292254-218292657 | promoter,gene body | 4.19e-01 | 2.69e-01 | 2.73e+00 | 6.29e-03 | 9.07e-03 | 1.50e-01 |
| LUSC | cg24533564 | chr2:218290745 | CGI:chr2:218292254-218292657 | promoter,gene body | 4.25e-01 | 5.26e-01 | -3.16e+00 | 1.60e-03 | 3.58e-03 | -1.01e-01 |
| BLCA | cg25353281 | chr2:218290655 | CGI:chr2:218292254-218292657 | promoter,gene body | 2.95e-01 | 4.17e-01 | -2.62e+00 | 8.68e-03 | 1.26e-02 | -1.22e-01 |
| KIRP | cg25353281 | chr2:218290655 | CGI:chr2:218292254-218292657 | promoter,gene body | 3.98e-01 | 2.19e-01 | 3.14e+00 | 1.68e-03 | 2.83e-03 | 1.79e-01 |
| KIRP | cg24533564 | chr2:218290745 | CGI:chr2:218292254-218292657 | promoter,gene body | 6.48e-01 | 5.47e-01 | 3.28e+00 | 1.03e-03 | 1.86e-03 | 1.01e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg25353281 | chr2:218290655 | CGI:chr2:218292254-218292657 | promoter,gene body | 6.74e-01 | 4.89e-01 | 7.25e+00 | 4.23e-13 | 1.34e-12 | 1.85e-01 |
Top |
Exon skipping events with PSI in TCGA for TMBIM1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for TMBIM1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for TMBIM1 |
| TFs related to TMBIM1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| READ | GLIS1 | TMBIM1 | 4.22e+00 | 9.82e-01 | 3.27e+00 | 5.54e-03 | Male-biased |
| READ | MYCN | TMBIM1 | 4.09e+00 | 9.82e-01 | 2.82e+00 | 1.67e-03 | Male-biased |
| READ | PLAGL2 | TMBIM1 | 4.06e+00 | 9.83e-01 | 1.97e+00 | 7.52e-05 | Male-biased |
| TMBIM1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for TMBIM1 |
| RBPs related to ES in TMBIM1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LIHC | HNRNPH2 | exon_skip_346730 | 6.92e+00 | 9.84e-01 | 6.11e+00 | 6.09e-04 | Male-biased |
| LUSC | BRUNOL6 | exon_skip_346732 | 6.73e+00 | 2.39e-03 | 7.24e+00 | 9.86e-01 | Female-biased |
| COAD | HNRNPH2 | exon_skip_346729 | 7.18e+00 | 9.87e-01 | 6.55e+00 | 6.74e-04 | Male-biased |
| COAD | HNRNPH2 | exon_skip_346730 | 7.39e+00 | 9.88e-01 | 6.79e+00 | 9.50e-04 | Male-biased |
| COAD | HNRNPH2 | exon_skip_346732 | 7.16e+00 | 9.86e-01 | 6.63e+00 | 1.50e-03 | Male-biased |
| DLBC | hnRNPK | exon_skip_346692 | 8.88e+00 | 1.41e-02 | 9.19e+00 | 9.82e-01 | Female-biased |
| DLBC | YB-1 | exon_skip_346700 | 9.87e+00 | 9.89e-01 | 9.53e+00 | 9.09e-03 | Male-biased |
| CHOL | CNOT4 | exon_skip_346721 | 7.18e+00 | 8.55e-03 | 7.60e+00 | 9.81e-01 | Female-biased |
| CHOL | ZC3H10 | exon_skip_346721 | 6.83e+00 | 9.83e-01 | 6.14e+00 | 1.18e-03 | Male-biased |
| LGG | HNRNPH2 | exon_skip_346730 | 6.12e+00 | 1.47e-03 | 6.64e+00 | 9.82e-01 | Female-biased |
| GBM | HNRNPH2 | exon_skip_346730 | 6.84e+00 | 9.83e-01 | 6.35e+00 | 2.09e-03 | Male-biased |
| PAAD | BRUNOL6 | exon_skip_346729 | 6.51e+00 | 5.12e-03 | 6.87e+00 | 9.80e-01 | Female-biased |
| KIRC | ZC3H10 | exon_skip_346721 | 6.43e+00 | 1.62e-03 | 6.92e+00 | 9.84e-01 | Female-biased |
| TMBIM1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12474265 | chr2:215215405:C:A | - | 0.138603615742017 | 0.0130947832587914 | LIHC | Female-baised eQTL |
| rs7424551 | chr2:215214440:G:A | - | 0.13526595358471 | 0.0198660756171915 | LIHC | Female-baised eQTL |
| rs4315521 | chr2:215220303:C:T | - | 0.13526595358471 | 0.0198660756171915 | LIHC | Female-baised eQTL |
| rs35183728 | chr2:215237188:T:C | - | 0.12915088754101 | 0.0281942675813711 | LIHC | Female-baised eQTL |
| rs4672860 | chr2:217924965:A:G | - | 0.237792415157779 | 0.0473295488390584 | LIHC | Female-baised eQTL |
| rs1552161 | chr2:212504504:A:G | - | 0.184147624215901 | 0.0118497023102104 | BLCA | Female-baised eQTL |
| rs201643310 | chr2:223016427:C:T | - | 0.192091072716469 | 0.0499890944218518 | BLCA | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17701917 | chr2:213575082:T:C | - | 0.106384987326177 | 0.00214280985909199 | LUAD | Male-baised eQTL |
| rs77999946 | chr2:213398963:A:G | - | 0.104179526410449 | 0.00247745085900355 | LUAD | Male-baised eQTL |
| rs3770154 | chr2:221473195:G:T | - | -0.0962359704361583 | 0.00014396381840662 | COAD | Male-baised eQTL |
| rs10933018 | chr2:223804712:T:G | - | 0.0765775900618515 | 0.00348688157496635 | COAD | Male-baised eQTL |
| rs28631964 | chr2:223809819:C:A | - | 0.0757246517083899 | 0.00401723688365064 | COAD | Male-baised eQTL |
| rs11884160 | chr2:223808862:G:A | - | 0.0745414014649402 | 0.00476564257833225 | COAD | Male-baised eQTL |
| rs17243807 | chr2:223810151:G:A | - | 0.0738972375169317 | 0.00505354796177142 | COAD | Male-baised eQTL |
| rs28599833 | chr2:223809885:C:A | - | 0.0719813453492931 | 0.00695995698245286 | COAD | Male-baised eQTL |
| rs67899857 | chr2:223810021:C:T | - | 0.0719813453492931 | 0.00695995698245286 | COAD | Male-baised eQTL |
| rs13416180 | chr2:223810831:A:C | - | 0.0712246150915913 | 0.00752923409648244 | COAD | Male-baised eQTL |
| rs7576099 | chr2:223811680:G:C | - | 0.0712246150915913 | 0.00752923409648244 | COAD | Male-baised eQTL |
| rs13390749 | chr2:223810591:G:A | - | 0.0693760411870816 | 0.0102062734606633 | COAD | Male-baised eQTL |
| rs7605287 | chr2:223812054:A:G | - | 0.0683574256298967 | 0.0115847621092672 | COAD | Male-baised eQTL |
| rs6757973 | chr2:223812498:A:T | - | 0.0683574256298967 | 0.0115847621092672 | COAD | Male-baised eQTL |
| rs6730212 | chr2:223812921:G:A | - | 0.0683574256298967 | 0.0115847621092672 | COAD | Male-baised eQTL |
| rs6436436 | chr2:223812155:A:T | - | 0.0669489674180539 | 0.0130578324096743 | COAD | Male-baised eQTL |
| rs62185132 | chr2:223818436:G:A | - | 0.0674426554815781 | 0.0135080988687312 | COAD | Male-baised eQTL |
| rs12467861 | chr2:223808298:T:C | - | 0.0662276066140645 | 0.0142264784033259 | COAD | Male-baised eQTL |
| rs10197448 | chr2:223819812:T:C | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs13407046 | chr2:223820251:C:T | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs28378706 | chr2:223820617:T:C | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs28398161 | chr2:223820644:T:C | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs10167473 | chr2:223821483:A:G | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs10191265 | chr2:223821520:C:T | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs1533609 | chr2:223821692:G:A | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs1533608 | chr2:223821811:A:G | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs1533607 | chr2:223822001:A:T | - | 0.0669576573670118 | 0.0143095932632915 | COAD | Male-baised eQTL |
| rs7592479 | chr2:223817649:T:A | - | 0.0669606225741044 | 0.0147238327936006 | COAD | Male-baised eQTL |
| rs10193173 | chr2:223817950:T:C | - | 0.0669606225741044 | 0.0147238327936006 | COAD | Male-baised eQTL |
| rs10180797 | chr2:223817960:G:A | - | 0.0669606225741044 | 0.0147238327936006 | COAD | Male-baised eQTL |
| rs10180900 | chr2:223818042:G:A | - | 0.0669606225741044 | 0.0147238327936006 | COAD | Male-baised eQTL |
| rs7587119 | chr2:223814549:G:A | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs13408145 | chr2:223815234:C:T | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs13382611 | chr2:223815258:A:G | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs7577788 | chr2:223817015:C:T | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs7578072 | chr2:223817088:G:T | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs7604417 | chr2:223817345:A:G | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs10180835 | chr2:223818144:C:T | - | 0.0666604797599302 | 0.0151609453826333 | COAD | Male-baised eQTL |
| rs6752410 | chr2:223823349:G:A | - | 0.0656352897715421 | 0.016519913916354 | COAD | Male-baised eQTL |
| rs13421277 | chr2:223823993:C:T | - | 0.0656352897715421 | 0.016519913916354 | COAD | Male-baised eQTL |
| rs13421452 | chr2:223824027:G:A | - | 0.0656352897715421 | 0.016519913916354 | COAD | Male-baised eQTL |
| rs12373615 | chr2:223833720:A:G | - | 0.0642428576052887 | 0.0170113630456723 | COAD | Male-baised eQTL |
| rs62190997 | chr2:226805496:T:A | - | -0.100021779549566 | 0.0173511757221998 | COAD | Male-baised eQTL |
| rs62190998 | chr2:226806519:A:G | - | -0.100021779549566 | 0.0173511757221998 | COAD | Male-baised eQTL |
| rs56105950 | chr2:226808445:T:C | - | -0.100021779549566 | 0.0173511757221998 | COAD | Male-baised eQTL |
| rs10933162 | chr2:226909424:T:A | - | -0.114537456716743 | 0.0180263076559309 | COAD | Male-baised eQTL |
| rs1560253 | chr2:226815097:T:C | - | -0.0993547105126561 | 0.0186228446104762 | COAD | Male-baised eQTL |
| rs2396427 | chr2:226815395:A:G | - | -0.0993547105126561 | 0.0186228446104762 | COAD | Male-baised eQTL |
| rs6757133 | chr2:223824782:G:A | - | 0.0635681228732007 | 0.0222593550737405 | COAD | Male-baised eQTL |
| rs10174440 | chr2:223816397:C:T | - | 0.063578201810281 | 0.0227949944709844 | COAD | Male-baised eQTL |
| rs62191054 | chr2:226904936:C:T | - | -0.110641922146577 | 0.0239242048169607 | COAD | Male-baised eQTL |
| rs9288583 | chr2:223835122:T:C | - | 0.0630291883254285 | 0.0244687154325317 | COAD | Male-baised eQTL |
| rs12466101 | chr2:211203067:G:A | - | -0.0689909309564423 | 0.0252164277998418 | COAD | Male-baised eQTL |
| rs10192352 | chr2:219737117:G:C | - | -0.0644643303806431 | 0.0252794459344651 | COAD | Male-baised eQTL |
| rs6731418 | chr2:223825046:A:G | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs10181119 | chr2:223825743:A:G | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs6746917 | chr2:223827179:G:A | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs10177420 | chr2:223827575:G:A | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs28561834 | chr2:223829124:G:T | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs28430762 | chr2:223829125:C:T | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs11897973 | chr2:223829328:T:C | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs6436439 | chr2:223830924:C:T | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs12694622 | chr2:223832234:G:A | - | 0.0627397512964054 | 0.0253777021742565 | COAD | Male-baised eQTL |
| rs62191000 | chr2:226810450:G:C | - | -0.0968540033160307 | 0.0262238236385945 | COAD | Male-baised eQTL |
| rs16822696 | chr2:226811039:T:C | - | -0.0968540033160307 | 0.0262238236385945 | COAD | Male-baised eQTL |
| rs62191001 | chr2:226811066:C:G | - | -0.0968540033160307 | 0.0262238236385945 | COAD | Male-baised eQTL |
| rs62191002 | chr2:226811304:A:C | - | -0.0968540033160307 | 0.0262238236385945 | COAD | Male-baised eQTL |
| rs62191003 | chr2:226811440:T:C | - | -0.0968540033160307 | 0.0262238236385945 | COAD | Male-baised eQTL |
| rs62191004 | chr2:226811599:A:G | - | -0.0968540033160307 | 0.0262238236385945 | COAD | Male-baised eQTL |
| rs16845555 | chr2:211202396:C:G | - | -0.0683898922853912 | 0.0274849341135649 | COAD | Male-baised eQTL |
| rs13402515 | chr2:223828936:G:A | - | 0.0623614619526095 | 0.0275244772708909 | COAD | Male-baised eQTL |
| rs56085860 | chr2:226813895:T:C | - | -0.0961967184355422 | 0.0279804586312041 | COAD | Male-baised eQTL |
| rs62191006 | chr2:226814466:C:A | - | -0.0961967184355422 | 0.0279804586312041 | COAD | Male-baised eQTL |
| rs12373774 | chr2:223833840:C:T | - | 0.0620066918785568 | 0.0280284308955887 | COAD | Male-baised eQTL |
| rs7600912 | chr2:223814548:T:C | - | 0.0621462296431806 | 0.0317147093722186 | COAD | Male-baised eQTL |
| rs10200716 | chr2:223814930:T:C | - | 0.0609267052894292 | 0.0347531714937182 | COAD | Male-baised eQTL |
| rs6436437 | chr2:223812637:T:C | - | 0.0608146854077894 | 0.0352244115529554 | COAD | Male-baised eQTL |
| rs7591771 | chr2:223816993:T:C | - | 0.061106209614908 | 0.0354603212562444 | COAD | Male-baised eQTL |
| rs77224808 | chr2:211195618:C:G | - | -0.0797754874406407 | 0.0380289919956968 | COAD | Male-baised eQTL |
| rs12694318 | chr2:214136191:A:G | - | 0.0638382853885384 | 0.0389415937550118 | COAD | Male-baised eQTL |
| rs6722305 | chr2:227634141:G:T | - | -0.0795468151912975 | 0.0410748687052846 | COAD | Male-baised eQTL |
| rs76231041 | chr2:226805223:G:A | - | -0.0969985155551784 | 0.0413506337077859 | COAD | Male-baised eQTL |
| rs13011568 | chr2:214060912:T:C | - | 0.0682641442733477 | 0.0425132716383364 | COAD | Male-baised eQTL |
| rs59004229 | chr2:227632753:T:A | - | 0.0835125387201928 | 0.046836776182424 | COAD | Male-baised eQTL |
| rs1562297 | chr2:223816910:C:T | - | 0.0583910006635171 | 0.0474734184417566 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000135926 |
| CpG Site: cg03627290 | |
| Position to Gene: gene | |
| Male Effect: -0.170837430589648 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg03627290 | chr2:218290525 | gene | -0.170837430589648 | 2.69035594171499e-21 | -0.6201747815487988 | 4.3079624879458025e-25 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TMBIM1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000135926 | TMBIM1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
