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Gene: ENSG00000135269 |
Summary for TES |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000135269 | Gene symbol | TES |
| Gene name | testin LIM domain protein | |
| HGNC | 14620 | |
| Entrez ID | 26136 | |
| Gene type | protein_coding | |
| Synonyms | TES|DKFZP586B2022|TESS-2|TESTIN | |
| UniProtAcc | Q9UGI8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TES |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TES | 4.88e+03 | -1.89e+00 | 2.37e-01 | -7.96e+00 | 1.75e-15 | 1.32e-13 | BLCA |
| TES | 2.57e+03 | 2.41e+00 | 3.25e-01 | 7.41e+00 | 1.24e-13 | 3.97e-12 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for TES |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for TES |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg00088880 | chr7:116209739 | CGI:chr7:116210316-116210974 | promoter | 8.28e-01 | 9.42e-01 | -3.50e+00 | 4.72e-04 | 1.27e-03 | -1.14e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for TES |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for TES |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for TES |
| TFs related to TES. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | FOXD2 | TES | 2.93e+00 | 4.15e-03 | 4.08e+00 | 9.85e-01 | Female-biased |
| CHOL | FOXF1 | TES | 3.01e+00 | 6.22e-03 | 4.05e+00 | 9.82e-01 | Female-biased |
| CHOL | MEIS1 | TES | 3.51e+00 | 9.28e-03 | 4.46e+00 | 9.85e-01 | Female-biased |
| CHOL | NFATC3 | TES | 4.04e+00 | 1.11e-02 | 4.95e+00 | 9.86e-01 | Female-biased |
| CHOL | NKX6-3 | TES | 3.62e+00 | 1.37e-02 | 4.47e+00 | 9.80e-01 | Female-biased |
| CHOL | SKOR2 | TES | 3.80e+00 | 1.20e-02 | 4.69e+00 | 9.84e-01 | Female-biased |
| LAML | FOXD2 | TES | 2.37e+00 | 1.23e-04 | 4.31e+00 | 9.89e-01 | Female-biased |
| LAML | FOXF1 | TES | 2.31e+00 | 1.30e-04 | 4.24e+00 | 9.87e-01 | Female-biased |
| LAML | FOXP2 | TES | 2.11e+00 | 1.38e-04 | 4.02e+00 | 9.82e-01 | Female-biased |
| LAML | HMX1 | TES | 2.78e+00 | 3.15e-04 | 4.52e+00 | 9.92e-01 | Female-biased |
| LAML | HOXB3 | TES | 4.11e+00 | 4.94e-03 | 5.19e+00 | 9.92e-01 | Female-biased |
| LAML | IRF4 | TES | 3.63e+00 | 4.12e-03 | 4.76e+00 | 9.90e-01 | Female-biased |
| LAML | IRF5 | TES | 4.28e+00 | 1.61e-02 | 5.05e+00 | 9.80e-01 | Female-biased |
| LAML | IRF8 | TES | 3.42e+00 | 3.82e-03 | 4.56e+00 | 9.88e-01 | Female-biased |
| LAML | MEIS1 | TES | 3.01e+00 | 5.81e-04 | 4.62e+00 | 9.92e-01 | Female-biased |
| LAML | MSX1 | TES | 2.44e+00 | 8.84e-05 | 4.45e+00 | 9.91e-01 | Female-biased |
| LAML | MSX2 | TES | 2.32e+00 | 6.87e-05 | 4.38e+00 | 9.90e-01 | Female-biased |
| LAML | MYNN | TES | 2.05e+00 | 1.03e-04 | 4.02e+00 | 9.82e-01 | Female-biased |
| LAML | NFATC3 | TES | 4.00e+00 | 6.90e-03 | 5.00e+00 | 9.89e-01 | Female-biased |
| LAML | NKX6-3 | TES | 3.18e+00 | 1.03e-03 | 4.65e+00 | 9.92e-01 | Female-biased |
| LAML | POU3F1 | TES | 3.89e+00 | 1.46e-03 | 5.29e+00 | 9.96e-01 | Female-biased |
| LAML | POU3F4 | TES | 4.01e+00 | 1.55e-03 | 5.40e+00 | 9.96e-01 | Female-biased |
| LAML | SKOR2 | TES | 3.16e+00 | 6.03e-04 | 4.76e+00 | 9.94e-01 | Female-biased |
| LAML | SRF | TES | 3.22e+00 | 1.57e-03 | 4.59e+00 | 9.91e-01 | Female-biased |
| LAML | TBP | TES | 2.38e+00 | 3.45e-04 | 4.10e+00 | 9.84e-01 | Female-biased |
| LAML | TLX3 | TES | 4.62e+00 | 3.35e-03 | 5.81e+00 | 9.95e-01 | Female-biased |
| LAML | ZKSCAN2 | TES | 2.25e+00 | 1.48e-04 | 4.15e+00 | 9.86e-01 | Female-biased |
| LAML | ZKSCAN7 | TES | 3.27e+00 | 6.41e-03 | 4.28e+00 | 9.82e-01 | Female-biased |
| LAML | ZNF136 | TES | 2.42e+00 | 2.82e-04 | 4.18e+00 | 9.86e-01 | Female-biased |
| LAML | ZNF334 | TES | 1.04e+00 | 1.63e-06 | 3.98e+00 | 9.81e-01 | Female-biased |
| MESO | FOXD2 | TES | 3.46e+00 | 8.61e-03 | 4.78e+00 | 9.87e-01 | Female-biased |
| MESO | FOXE1 | TES | 3.20e+00 | 9.90e-03 | 4.48e+00 | 9.82e-01 | Female-biased |
| MESO | MSX1 | TES | 3.67e+00 | 8.65e-03 | 4.99e+00 | 9.88e-01 | Female-biased |
| MESO | MSX2 | TES | 3.59e+00 | 8.67e-03 | 4.91e+00 | 9.88e-01 | Female-biased |
| MESO | MYNN | TES | 3.39e+00 | 1.01e-02 | 4.66e+00 | 9.84e-01 | Female-biased |
| MESO | NANOG | TES | 3.24e+00 | 1.01e-02 | 4.51e+00 | 9.83e-01 | Female-biased |
| MESO | STAT2 | TES | 2.66e+00 | 4.27e-03 | 4.17e+00 | 9.84e-01 | Female-biased |
| MESO | ZKSCAN2 | TES | 3.47e+00 | 1.12e-02 | 4.71e+00 | 9.84e-01 | Female-biased |
| MESO | ZNF334 | TES | 3.07e+00 | 1.72e-03 | 4.86e+00 | 9.94e-01 | Female-biased |
| MESO | ZNF418 | TES | 2.55e+00 | 1.90e-04 | 4.87e+00 | 9.96e-01 | Female-biased |
| MESO | ZNF570 | TES | 2.64e+00 | 3.56e-03 | 4.21e+00 | 9.85e-01 | Female-biased |
| MESO | ZNF79 | TES | 2.90e+00 | 1.39e-03 | 4.74e+00 | 9.94e-01 | Female-biased |
| PCPG | FOXD2 | TES | 3.95e+00 | 9.83e-01 | 2.59e+00 | 6.48e-04 | Male-biased |
| PCPG | FOXF1 | TES | 4.06e+00 | 9.85e-01 | 2.78e+00 | 1.03e-03 | Male-biased |
| PCPG | HMX1 | TES | 4.33e+00 | 9.89e-01 | 3.16e+00 | 1.86e-03 | Male-biased |
| PCPG | MEIS1 | TES | 4.61e+00 | 9.88e-01 | 3.69e+00 | 5.79e-03 | Male-biased |
| PCPG | MSX1 | TES | 4.20e+00 | 9.88e-01 | 2.82e+00 | 5.92e-04 | Male-biased |
| PCPG | MSX2 | TES | 4.07e+00 | 9.86e-01 | 2.69e+00 | 5.77e-04 | Male-biased |
| PCPG | MYNN | TES | 3.86e+00 | 9.80e-01 | 2.52e+00 | 7.22e-04 | Male-biased |
| PCPG | NANOG | TES | 3.88e+00 | 9.81e-01 | 2.52e+00 | 6.36e-04 | Male-biased |
| PCPG | NKX6-3 | TES | 4.47e+00 | 9.87e-01 | 3.52e+00 | 5.17e-03 | Male-biased |
| PCPG | POU3F1 | TES | 5.21e+00 | 9.93e-01 | 4.23e+00 | 4.67e-03 | Male-biased |
| PCPG | POU3F4 | TES | 5.25e+00 | 9.91e-01 | 4.36e+00 | 6.77e-03 | Male-biased |
| PCPG | SKOR2 | TES | 4.63e+00 | 9.91e-01 | 3.58e+00 | 3.29e-03 | Male-biased |
| PCPG | TLX3 | TES | 5.75e+00 | 9.84e-01 | 5.02e+00 | 1.45e-02 | Male-biased |
| PCPG | ZKSCAN2 | TES | 3.95e+00 | 9.82e-01 | 2.68e+00 | 1.07e-03 | Male-biased |
| PCPG | ZNF28 | TES | 2.49e+00 | 6.61e-04 | 3.86e+00 | 9.82e-01 | Female-biased |
| SKCM | ZNF334 | TES | 3.79e+00 | 9.25e-03 | 4.79e+00 | 9.82e-01 | Female-biased |
| TES related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for TES |
| RBPs related to ES in TES. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LUAD | FXR1 | exon_skip_470646 | 8.31e+00 | 1.24e-02 | 8.62e+00 | 9.81e-01 | Female-biased |
| READ | SART3 | exon_skip_470628 | 8.98e+00 | 9.89e-01 | 8.63e+00 | 7.19e-03 | Male-biased |
| KICH | SART3 | exon_skip_470628 | 8.48e+00 | 1.02e-02 | 8.80e+00 | 9.85e-01 | Female-biased |
| TES related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000135269 | AC116447.1,hsa-mir-4728,TES | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000135269 | AC116447.1,hsa-mir-665,TES | Male-specific ceRNA | TCGA-BLCA |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs62472480 | chr7:124348917:A:G | - | 0.0908368146359353 | 0.0322869850575611 | LUSC | Female-baised eQTL |
| rs35333087 | chr7:117879113:C:G | - | 0.0864062678388459 | 0.0347430226495108 | LUSC | Female-baised eQTL |
| rs35562243 | chr7:117880392:G:A | - | 0.0864062678388459 | 0.0347430226495108 | LUSC | Female-baised eQTL |
| rs77176779 | chr7:110862850:T:G | - | 0.161557758863124 | 0.00140045326577966 | BLCA | Female-baised eQTL |
| rs78008024 | chr7:110866753:A:G | - | 0.161557758863124 | 0.00140045326577966 | BLCA | Female-baised eQTL |
| rs17158079 | chr7:110869523:T:C | - | 0.161557758863124 | 0.00140045326577966 | BLCA | Female-baised eQTL |
| rs73425075 | chr7:110902604:G:A | - | 0.149079277642888 | 0.00355441686762228 | BLCA | Female-baised eQTL |
| rs3807974 | chr7:116235887:T:C | gene | 0.119859314948551 | 0.0191842557717483 | BLCA | Female-baised eQTL |
| rs9987062 | chr7:108767667:A:G | - | -0.0945126783802639 | 0.0281668123769059 | BLCA | Female-baised eQTL |
| rs4428611 | chr7:116211927:G:A | gene,promoter | -0.107545484394126 | 0.0430918529640493 | BLCA | Female-baised eQTL |
| rs77236693 | chr7:114980451:C:T | - | 0.103009148371178 | 0.0437652283072956 | BLCA | Female-baised eQTL |
| rs117714788 | chr7:114330569:A:G | - | 0.102192523997247 | 0.0491554403683399 | BLCA | Female-baised eQTL |
| rs11763797 | chr7:114331360:T:C | - | 0.102192523997247 | 0.0491554403683399 | BLCA | Female-baised eQTL |
| rs113939847 | chr7:114338835:T:A | - | 0.102192523997247 | 0.0491554403683399 | BLCA | Female-baised eQTL |
| rs11764981 | chr7:109058183:T:C | - | 0.0735696161951514 | 0.00211259965929962 | LUAD | Female-baised eQTL |
| rs73720308 | chr7:123933869:A:G | - | 0.0504639176707446 | 0.0101637031258388 | LUAD | Female-baised eQTL |
| rs2283053 | chr7:116786965:A:G | - | 0.0375951858146712 | 0.0220774187809217 | LUAD | Female-baised eQTL |
| rs11981032 | chr7:112046098:C:T | - | 0.0715472732757677 | 0.0241859114110445 | LUAD | Female-baised eQTL |
| rs4730725 | chr7:116265409:T:G | - | 0.0471176866018912 | 0.0389893058007855 | LUAD | Female-baised eQTL |
| rs17138592 | chr7:116312590:C:T | - | 0.0483305365720831 | 0.0425361148798997 | LUAD | Female-baised eQTL |
| rs4730730 | chr7:116305047:A:G | - | 0.0484306810077266 | 0.0428132895569002 | LUAD | Female-baised eQTL |
| rs12674399 | chr7:124005730:G:A | - | 0.0466434309253004 | 0.043820558072158 | LUAD | Female-baised eQTL |
| rs12672313 | chr7:116316376:C:A | - | 0.047204153424367 | 0.0446743323392245 | LUAD | Female-baised eQTL |
| rs1528243 | chr7:116330610:G:A | - | 0.047204153424367 | 0.0446743323392245 | LUAD | Female-baised eQTL |
| rs73451098 | chr7:116319546:G:A | - | 0.047224958836634 | 0.0446821388793541 | LUAD | Female-baised eQTL |
| rs73451102 | chr7:116324417:A:T | - | 0.047224958836634 | 0.0446821388793541 | LUAD | Female-baised eQTL |
| rs12671149 | chr7:116226826:A:G | gene | 0.0475081638799026 | 0.0452486839977293 | LUAD | Female-baised eQTL |
| rs12537066 | chr7:116309859:C:T | - | 0.0481209794601483 | 0.0456867637734164 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10240841 | chr7:113550005:G:A | - | 0.338026611267188 | 0.0297492714554038 | PCPG | Male-baised eQTL |
| rs140421017 | chr7:113537895:A:G | - | 0.334632813331086 | 0.0350812002067599 | PCPG | Male-baised eQTL |
| rs10249689 | chr7:113546615:C:T | - | 0.334632813331086 | 0.0350812002067599 | PCPG | Male-baised eQTL |
| rs7782995 | chr7:109119183:C:T | - | -0.0337449731341051 | 0.0307630145657496 | LUSC | Male-baised eQTL |
| rs78447765 | chr7:116429314:T:C | - | 0.0700689651791374 | 0.0120394136093272 | STAD | Male-baised eQTL |
| rs16869649 | chr7:113782848:G:A | - | 0.0522568980982896 | 0.0259117360289476 | KIRC | Male-baised eQTL |
| rs1404859 | chr7:110080723:G:A | - | 0.0366471577826336 | 0.0269206117409435 | KIRC | Male-baised eQTL |
| rs17136650 | chr7:113799008:G:A | - | 0.0510488794968193 | 0.0458255071108783 | KIRC | Male-baised eQTL |
| rs7811321 | chr7:110680249:C:T | - | 0.10072758001744 | 0.00204228856489777 | LUAD | Male-baised eQTL |
| rs7807511 | chr7:110680188:A:G | - | 0.101080435980462 | 0.00292336467934439 | LUAD | Male-baised eQTL |
| rs4730549 | chr7:112460715:A:G | - | 0.068354981297618 | 0.00505082629572227 | LUAD | Male-baised eQTL |
| rs4730548 | chr7:112452628:G:T | - | 0.0682411645566403 | 0.00526825072036625 | LUAD | Male-baised eQTL |
| rs73443807 | chr7:124707295:T:C | - | 0.0905035388998542 | 0.0135877598103464 | LUAD | Male-baised eQTL |
| rs55954386 | chr7:112462545:A:G | - | 0.0615402756306876 | 0.0172449838899002 | LUAD | Male-baised eQTL |
| rs17159684 | chr7:112463337:A:G | - | 0.0615402756306876 | 0.0172449838899002 | LUAD | Male-baised eQTL |
| rs4727771 | chr7:112452292:C:T | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs10500007 | chr7:112452889:T:C | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs76283700 | chr7:112454958:C:T | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs6967894 | chr7:112456825:G:A | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs6968084 | chr7:112457066:C:T | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs6945176 | chr7:112458141:C:T | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs56020731 | chr7:112460163:A:T | - | 0.0610864935582991 | 0.0194351686507128 | LUAD | Male-baised eQTL |
| rs112715306 | chr7:124720921:G:A | - | 0.0890136714742842 | 0.0203598325769194 | LUAD | Male-baised eQTL |
| rs10238164 | chr7:121768547:A:T | - | 0.0717122342877848 | 0.000946521658732258 | COAD | Male-baised eQTL |
| rs6972380 | chr7:121766570:A:G | - | 0.0695268462815024 | 0.00152420127764124 | COAD | Male-baised eQTL |
| rs6964759 | chr7:121774073:T:C | - | 0.0693659974573529 | 0.0015833011567378 | COAD | Male-baised eQTL |
| rs1544614 | chr7:121775126:G:T | - | 0.0693659974573529 | 0.0015833011567378 | COAD | Male-baised eQTL |
| rs1544615 | chr7:121775130:T:C | - | 0.0688467691461254 | 0.00198710078649007 | COAD | Male-baised eQTL |
| rs10226423 | chr7:121773231:C:G | - | 0.0661092273401135 | 0.00321047427191047 | COAD | Male-baised eQTL |
| rs12670840 | chr7:116485118:C:T | - | 0.0686807166910404 | 0.0129878763242107 | COAD | Male-baised eQTL |
| rs12673212 | chr7:121845571:G:C | - | 0.0820668178661108 | 0.014061087325869 | COAD | Male-baised eQTL |
| rs12673871 | chr7:121847150:G:C | - | 0.0820668178661108 | 0.014061087325869 | COAD | Male-baised eQTL |
| rs57170860 | chr7:121843337:C:T | - | 0.0809872923649899 | 0.0142798727036659 | COAD | Male-baised eQTL |
| rs58748383 | chr7:121823576:A:G | - | 0.08248855410214 | 0.0143403930038912 | COAD | Male-baised eQTL |
| rs12671267 | chr7:121831898:G:A | - | 0.0834960112722809 | 0.0149270207855043 | COAD | Male-baised eQTL |
| rs275545 | chr7:108994885:A:G | - | -0.0697108352251745 | 0.0184602902015461 | COAD | Male-baised eQTL |
| rs11543745 | chr7:121839012:C:T | - | 0.0794840782878779 | 0.0186015731276427 | COAD | Male-baised eQTL |
| rs10953948 | chr7:121839117:C:T | - | 0.0794840782878779 | 0.0186015731276427 | COAD | Male-baised eQTL |
| rs35807933 | chr7:121839587:G:A | - | 0.0794840782878779 | 0.0186015731276427 | COAD | Male-baised eQTL |
| rs275557 | chr7:109013995:G:A | - | -0.0673045413423194 | 0.0222523711727706 | COAD | Male-baised eQTL |
| rs78125164 | chr7:116109662:T:G | - | -0.122427335266758 | 0.0224550882474095 | COAD | Male-baised eQTL |
| rs672436 | chr7:109018084:A:G | - | -0.0666016556043664 | 0.0241402615461847 | COAD | Male-baised eQTL |
| rs73717719 | chr7:121826199:G:A | - | 0.0794349311037906 | 0.0254287638648888 | COAD | Male-baised eQTL |
| rs275547 | chr7:108991057:A:T | - | -0.0666796020273583 | 0.028665275573093 | COAD | Male-baised eQTL |
| rs275543 | chr7:108998710:A:G | - | -0.0655429733856592 | 0.0297308441785549 | COAD | Male-baised eQTL |
| rs28613932 | chr7:116206226:G:A | - | -0.0541871649144022 | 0.0333856479937937 | COAD | Male-baised eQTL |
| rs10279056 | chr7:116206703:A:G | - | -0.0537541668646808 | 0.0336616213011069 | COAD | Male-baised eQTL |
| rs275539 | chr7:108980067:C:G | - | -0.0652246392772563 | 0.0350964490361013 | COAD | Male-baised eQTL |
| rs670501 | chr7:108985128:T:C | - | -0.0648932777305308 | 0.0373989980107684 | COAD | Male-baised eQTL |
| rs61522074 | chr7:125674029:G:A | - | 0.056386247979795 | 0.03902002174546 | COAD | Male-baised eQTL |
| rs73231645 | chr7:125674030:C:G | - | 0.056386247979795 | 0.03902002174546 | COAD | Male-baised eQTL |
| rs10240134 | chr7:111994843:T:C | - | 0.0574713447174776 | 0.0401495090251683 | COAD | Male-baised eQTL |
| rs275538 | chr7:108980739:G:T | - | -0.0639586881930232 | 0.0410987734976661 | COAD | Male-baised eQTL |
| rs848366 | chr7:108896846:G:A | - | -0.0596846292704039 | 0.041221908545166 | COAD | Male-baised eQTL |
| rs9986915 | chr7:109354351:C:T | - | 0.0636933636764394 | 0.0429424159645587 | COAD | Male-baised eQTL |
| rs56165084 | chr7:109057548:G:T | - | 0.0592562994877034 | 0.0437644272005533 | COAD | Male-baised eQTL |
| rs275533 | chr7:109022978:A:G | - | -0.0602227011357016 | 0.0467905437694938 | COAD | Male-baised eQTL |
| rs35418834 | chr7:109066865:A:G | - | 0.0589221121292254 | 0.0480754987770567 | COAD | Male-baised eQTL |
| rs6964025 | chr7:109356087:T:C | - | 0.0617634127460417 | 0.0495105204889839 | COAD | Male-baised eQTL |
| rs275532 | chr7:109027396:A:G | - | -0.0597287260032265 | 0.0495276220952195 | COAD | Male-baised eQTL |
| rs12706675 | chr7:125682388:C:T | - | 0.0549434392641813 | 0.0497120977911805 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000135269 |
| CpG Site: cg12018521 | |
| Position to Gene: gene | |
| Male Effect: -0.442022262994889 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg12018521 | chr7:116218080 | gene | -0.442022262994889 | 8.42202854968339e-15 | -0.5402187611049567 | 2.7030063397555448e-18 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TES |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000135269 | TES | C0017636 | Glioblastoma | 1 | CTD_human |
| ENSG00000135269 | TES | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| ENSG00000135269 | TES | C0334588 | Giant Cell Glioblastoma | 1 | CTD_human |
| ENSG00000135269 | TES | C1621958 | Glioblastoma Multiforme | 1 | CTD_human |
