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Gene: ENSG00000133818 |
Summary for RRAS2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000133818 | Gene symbol | RRAS2 |
| Gene name | RAS related 2 | |
| HGNC | 17271 | |
| Entrez ID | 22800 | |
| Gene type | protein_coding | |
| Synonyms | RRAS2|TC21 | |
| UniProtAcc | P62070 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for RRAS2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| RRAS2 | 1.11e+03 | -1.05e+00 | 3.06e-01 | -3.43e+00 | 5.94e-04 | 1.36e-03 | KICH |
| RRAS2 | 9.37e+02 | -1.04e+00 | 9.40e-02 | -1.11e+01 | 1.29e-28 | 6.26e-28 | BRCA |
Top |
Sex-biased somatic mutation for RRAS2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for RRAS2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for RRAS2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for RRAS2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for RRAS2 |
| TFs related to RRAS2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PAAD | ALX3 | RRAS2 | 4.48e+00 | 9.82e-01 | 3.66e+00 | 1.07e-02 | Male-biased |
| PAAD | ALX4 | RRAS2 | 4.43e+00 | 9.82e-01 | 3.60e+00 | 1.02e-02 | Male-biased |
| PAAD | ARGFX | RRAS2 | 4.42e+00 | 9.89e-01 | 3.34e+00 | 2.92e-03 | Male-biased |
| PAAD | DRGX | RRAS2 | 4.20e+00 | 9.82e-01 | 3.31e+00 | 7.32e-03 | Male-biased |
| PAAD | PHOX2A | RRAS2 | 4.26e+00 | 9.83e-01 | 3.37e+00 | 7.34e-03 | Male-biased |
| PAAD | PROP1 | RRAS2 | 4.42e+00 | 9.84e-01 | 3.55e+00 | 8.24e-03 | Male-biased |
| PAAD | UNCX | RRAS2 | 4.08e+00 | 9.81e-01 | 3.16e+00 | 6.08e-03 | Male-biased |
| READ | ALX1 | RRAS2 | 4.26e+00 | 9.84e-01 | 3.19e+00 | 3.65e-03 | Male-biased |
| READ | ALX3 | RRAS2 | 4.70e+00 | 9.83e-01 | 3.92e+00 | 1.15e-02 | Male-biased |
| READ | ALX4 | RRAS2 | 4.68e+00 | 9.84e-01 | 3.87e+00 | 1.03e-02 | Male-biased |
| READ | ARGFX | RRAS2 | 4.55e+00 | 9.84e-01 | 3.70e+00 | 8.73e-03 | Male-biased |
| READ | BARX1 | RRAS2 | 4.31e+00 | 9.85e-01 | 3.25e+00 | 3.63e-03 | Male-biased |
| READ | DMRT2 | RRAS2 | 4.36e+00 | 9.88e-01 | 3.16e+00 | 2.23e-03 | Male-biased |
| READ | DRGX | RRAS2 | 4.52e+00 | 9.85e-01 | 3.62e+00 | 7.18e-03 | Male-biased |
| READ | FOXP3 | RRAS2 | 4.20e+00 | 9.82e-01 | 3.21e+00 | 4.89e-03 | Male-biased |
| READ | ISX | RRAS2 | 4.42e+00 | 9.85e-01 | 3.47e+00 | 5.78e-03 | Male-biased |
| READ | LHX2 | RRAS2 | 4.54e+00 | 9.88e-01 | 3.54e+00 | 4.95e-03 | Male-biased |
| READ | NKX2-2 | RRAS2 | 4.25e+00 | 9.85e-01 | 3.15e+00 | 3.26e-03 | Male-biased |
| READ | NKX3-2 | RRAS2 | 4.36e+00 | 9.86e-01 | 3.27e+00 | 3.42e-03 | Male-biased |
| READ | PHOX2A | RRAS2 | 4.57e+00 | 9.87e-01 | 3.63e+00 | 6.04e-03 | Male-biased |
| READ | PHOX2B | RRAS2 | 4.23e+00 | 9.84e-01 | 3.14e+00 | 3.32e-03 | Male-biased |
| READ | POU5F1B | RRAS2 | 4.22e+00 | 9.85e-01 | 3.08e+00 | 2.72e-03 | Male-biased |
| READ | PROP1 | RRAS2 | 4.68e+00 | 9.84e-01 | 3.87e+00 | 1.04e-02 | Male-biased |
| READ | PRRX1 | RRAS2 | 4.42e+00 | 9.85e-01 | 3.50e+00 | 6.34e-03 | Male-biased |
| READ | UNCX | RRAS2 | 4.48e+00 | 9.86e-01 | 3.52e+00 | 5.54e-03 | Male-biased |
| READ | ZNF232 | RRAS2 | 4.41e+00 | 9.85e-01 | 3.48e+00 | 6.10e-03 | Male-biased |
| READ | ZNF418 | RRAS2 | 3.99e+00 | 9.81e-01 | 1.69e+00 | 2.80e-05 | Male-biased |
| SKCM | ZNF418 | RRAS2 | 4.20e+00 | 9.17e-03 | 5.21e+00 | 9.86e-01 | Female-biased |
| THYM | ALX3 | RRAS2 | 4.40e+00 | 9.81e-01 | 3.73e+00 | 1.00e-02 | Male-biased |
| THYM | ALX4 | RRAS2 | 4.38e+00 | 9.82e-01 | 3.68e+00 | 8.96e-03 | Male-biased |
| THYM | DMRT2 | RRAS2 | 3.97e+00 | 9.80e-01 | 3.05e+00 | 3.36e-03 | Male-biased |
| THYM | PROP1 | RRAS2 | 4.37e+00 | 9.82e-01 | 3.65e+00 | 8.39e-03 | Male-biased |
| THYM | UNCX | RRAS2 | 4.11e+00 | 9.80e-01 | 3.33e+00 | 6.15e-03 | Male-biased |
| RRAS2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for RRAS2 |
| RBPs related to ES in RRAS2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | ZFP36 | exon_skip_69340 | 9.25e+00 | 9.88e-01 | 8.89e+00 | 8.95e-03 | Male-biased |
| ACC | SNRNP70 | exon_skip_69336 | 6.97e+00 | 8.57e-03 | 7.40e+00 | 9.80e-01 | Female-biased |
| UVM | CNOT4 | exon_skip_69337 | 8.45e+00 | 1.29e-02 | 8.73e+00 | 9.82e-01 | Female-biased |
| LIHC | ZFP36 | exon_skip_69340 | 9.65e+00 | 9.94e-01 | 9.12e+00 | 3.37e-03 | Male-biased |
| DLBC | CNOT4 | exon_skip_69337 | 8.40e+00 | 6.44e-03 | 8.78e+00 | 9.88e-01 | Female-biased |
| CHOL | ZFP36 | exon_skip_69340 | 9.12e+00 | 1.31e-02 | 9.49e+00 | 9.84e-01 | Female-biased |
| MESO | CNOT4 | exon_skip_69337 | 8.29e+00 | 1.05e-02 | 8.63e+00 | 9.83e-01 | Female-biased |
| PAAD | CNOT4 | exon_skip_69337 | 8.24e+00 | 3.60e-03 | 8.62e+00 | 9.90e-01 | Female-biased |
| RRAS2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs72868214 | chr11:15501615:C:T | - | 0.149452514242781 | 0.00915667443642822 | PCPG | Female-baised eQTL |
| rs2351097 | chr11:15538640:C:A | - | 0.149178757432467 | 0.0122957604622485 | PCPG | Female-baised eQTL |
| rs55890157 | chr11:15539346:C:A | - | 0.149178757432467 | 0.0122957604622485 | PCPG | Female-baised eQTL |
| rs11023602 | chr11:15507298:G:T | - | 0.150407632516479 | 0.0131586412710735 | PCPG | Female-baised eQTL |
| rs11023591 | chr11:15485622:G:A | - | 0.144444680433848 | 0.0151672743329806 | PCPG | Female-baised eQTL |
| rs12365899 | chr11:15476013:A:T | - | 0.139201394167707 | 0.0239069477157674 | PCPG | Female-baised eQTL |
| rs10832445 | chr11:15476815:C:T | - | 0.139201394167707 | 0.0239069477157674 | PCPG | Female-baised eQTL |
| rs12363765 | chr11:15477691:G:A | - | 0.139201394167707 | 0.0239069477157674 | PCPG | Female-baised eQTL |
| rs7481938 | chr11:15477980:T:C | - | 0.139201394167707 | 0.0239069477157674 | PCPG | Female-baised eQTL |
| rs2351047 | chr11:15558942:T:A | - | 0.133232584055303 | 0.044349195298746 | PCPG | Female-baised eQTL |
| rs4456242 | chr11:19683850:T:G | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs890141 | chr11:19684144:C:T | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs7130790 | chr11:19686293:A:C | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs7104436 | chr11:19686972:C:A | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs4757838 | chr11:19687305:T:C | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs7938278 | chr11:19687965:A:C | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs7120062 | chr11:19688477:C:T | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs4267048 | chr11:19688670:T:C | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs7110826 | chr11:19690033:T:C | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs2403529 | chr11:19699445:C:G | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs1895724 | chr11:19702826:A:T | - | -0.142319111055704 | 0.0228985126105653 | PAAD | Female-baised eQTL |
| rs1364793 | chr11:19690232:A:G | - | -0.141941254603013 | 0.0241952935711447 | PAAD | Female-baised eQTL |
| rs10741792 | chr11:19690940:T:G | - | -0.141941254603013 | 0.0241952935711447 | PAAD | Female-baised eQTL |
| rs2009725 | chr11:19694451:G:A | - | -0.141941254603013 | 0.0241952935711447 | PAAD | Female-baised eQTL |
| rs11022545 | chr11:12912136:G:A | - | 0.110435354097045 | 0.0367063332509435 | PAAD | Female-baised eQTL |
| rs7120593 | chr11:19686970:T:C | - | -0.134314577146148 | 0.0369398537803015 | PAAD | Female-baised eQTL |
| rs138290177 | chr11:19175216:G:A | - | 0.139317992743858 | 0.0055178733408199 | SARC | Female-baised eQTL |
| rs59810756 | chr11:4575419:T:G | - | 0.196758044001488 | 0.00354526824240279 | LIHC | Female-baised eQTL |
| rs76446722 | chr11:4576742:A:G | - | 0.184339116336747 | 0.0193546914501536 | LIHC | Female-baised eQTL |
| rs7118953 | chr11:17595334:C:T | - | 0.109749338503311 | 0.0454269148393094 | BLCA | Female-baised eQTL |
| rs7126777 | chr11:17596751:C:T | - | 0.109749338503311 | 0.0454269148393094 | BLCA | Female-baised eQTL |
| rs11024335 | chr11:17597434:A:C | - | 0.109749338503311 | 0.0454269148393094 | BLCA | Female-baised eQTL |
| rs757983 | chr11:17598033:G:A | - | 0.109749338503311 | 0.0454269148393094 | BLCA | Female-baised eQTL |
| rs7130159 | chr11:11490727:G:T | - | 0.0748130922003707 | 0.000320105414557678 | LUAD | Female-baised eQTL |
| rs35577167 | chr11:11492555:T:C | - | 0.0685131425255144 | 0.00497038564574151 | LUAD | Female-baised eQTL |
| rs6484951 | chr11:11490758:T:C | - | -0.0647409383092748 | 0.00748064817874141 | LUAD | Female-baised eQTL |
| rs4512797 | chr11:18935617:G:A | - | 0.0958701114520626 | 0.00769307796074194 | LUAD | Female-baised eQTL |
| rs1386426 | chr11:11491166:G:T | - | 0.0646272994764732 | 0.00878914622381271 | LUAD | Female-baised eQTL |
| rs11024884 | chr11:18928545:A:G | - | 0.0927107040322157 | 0.0110606834171101 | LUAD | Female-baised eQTL |
| rs7941536 | chr11:18923102:G:T | - | 0.0918374051495893 | 0.0127000802746305 | LUAD | Female-baised eQTL |
| rs2052691 | chr11:10642874:G:A | - | 0.0519913363634923 | 0.0216712736154194 | LUAD | Female-baised eQTL |
| rs10837757 | chr11:5280814:A:G | - | 0.086196016786495 | 0.0217203287525467 | LUAD | Female-baised eQTL |
| rs10831620 | chr11:11471994:C:T | - | 0.0624533321658614 | 0.0239592511072236 | LUAD | Female-baised eQTL |
| rs11021871 | chr11:11472921:G:T | - | 0.0624533321658614 | 0.0239592511072236 | LUAD | Female-baised eQTL |
| rs10450577 | chr11:13967673:C:T | - | 0.0571787862738235 | 0.0291899311121068 | LUAD | Female-baised eQTL |
| rs4528305 | chr11:18867225:A:C | - | 0.0680502851232572 | 0.0296292109627917 | LUAD | Female-baised eQTL |
| rs77667795 | chr11:5819748:G:T | - | 0.0887602011425468 | 0.0307510817476697 | LUAD | Female-baised eQTL |
| rs72873106 | chr11:13957482:T:C | - | 0.0552561715921136 | 0.0371313226351717 | LUAD | Female-baised eQTL |
| rs11024865 | chr11:18885064:C:A | - | 0.0706657935016006 | 0.0384869143396388 | LUAD | Female-baised eQTL |
| rs7934003 | chr11:18885692:A:C | - | 0.0706657935016006 | 0.0384869143396388 | LUAD | Female-baised eQTL |
| rs56406826 | chr11:13953469:G:A | - | 0.0503860698399358 | 0.0424194602913316 | LUAD | Female-baised eQTL |
| rs12576021 | chr11:7266229:T:G | - | 0.0510263219688761 | 0.0429738710576981 | LUAD | Female-baised eQTL |
| rs79774351 | chr11:21028240:C:T | - | 0.0915923308385471 | 0.0436249666003581 | LUAD | Female-baised eQTL |
| rs11024864 | chr11:18884914:C:G | - | 0.0693259923681972 | 0.0439660057277632 | LUAD | Female-baised eQTL |
| rs10838356 | chr11:5572115:G:A | - | 0.0477886676522619 | 0.0444400793500283 | LUAD | Female-baised eQTL |
| rs7941658 | chr11:18858223:G:T | - | 0.0698382604532965 | 0.0450897898937161 | LUAD | Female-baised eQTL |
| rs12575802 | chr11:18856206:G:A | - | 0.0697234697630242 | 0.0459310751279069 | LUAD | Female-baised eQTL |
| rs71486886 | chr11:18873247:C:G | - | 0.0695437556623999 | 0.0472267488080147 | LUAD | Female-baised eQTL |
| rs12800236 | chr11:18880095:G:T | - | 0.0695437556623999 | 0.0472267488080147 | LUAD | Female-baised eQTL |
| rs6483543 | chr11:18860674:G:A | - | 0.0694797032963927 | 0.0474897829082521 | LUAD | Female-baised eQTL |
| rs6483544 | chr11:18862375:T:G | - | 0.0694797032963927 | 0.0474897829082521 | LUAD | Female-baised eQTL |
| rs36002518 | chr11:18863520:C:T | - | 0.0694797032963927 | 0.0474897829082521 | LUAD | Female-baised eQTL |
| rs12786014 | chr11:18863704:A:G | - | 0.0694797032963927 | 0.0474897829082521 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10768707 | chr11:5252692:T:C | - | -0.155647500891202 | 0.00790007229031201 | GBM | Male-baised eQTL |
| rs5010979 | chr11:5257923:T:C | - | -0.150886181420795 | 0.0145765779382052 | GBM | Male-baised eQTL |
| rs5010981 | chr11:5258125:C:A | - | -0.150886181420795 | 0.0145765779382052 | GBM | Male-baised eQTL |
| rs5010984 | chr11:5258258:T:C | - | -0.150886181420795 | 0.0145765779382052 | GBM | Male-baised eQTL |
| rs10734494 | chr11:5260304:C:T | - | -0.150886181420795 | 0.0145765779382052 | GBM | Male-baised eQTL |
| rs10768733 | chr11:5265926:C:T | - | -0.150856406266631 | 0.0162096474900658 | GBM | Male-baised eQTL |
| rs7121303 | chr11:5262937:T:C | - | -0.148140541359429 | 0.0212150910230294 | GBM | Male-baised eQTL |
| rs11822578 | chr11:5268076:G:C | - | -0.148328433034204 | 0.0221468969130438 | GBM | Male-baised eQTL |
| rs11032081 | chr11:4394089:G:A | - | 0.149009651721572 | 0.00112561722477845 | SARC | Male-baised eQTL |
| rs75123890 | chr11:4396231:A:G | - | 0.143977752117518 | 0.00180978298384517 | SARC | Male-baised eQTL |
| rs149676304 | chr11:4399098:T:G | - | 0.143977752117518 | 0.00180978298384517 | SARC | Male-baised eQTL |
| rs1426378 | chr11:4393643:G:A | - | 0.143241214888972 | 0.00200423709762637 | SARC | Male-baised eQTL |
| rs926101 | chr11:4390011:C:T | - | 0.140886892003362 | 0.00301893409854173 | SARC | Male-baised eQTL |
| rs5030768 | chr11:4390589:T:C | - | 0.140886892003362 | 0.00301893409854173 | SARC | Male-baised eQTL |
| rs11529910 | chr11:4401390:T:G | - | 0.137567315382515 | 0.00358173057374025 | SARC | Male-baised eQTL |
| rs117427540 | chr11:4407742:G:A | - | 0.1270005541882 | 0.00767931892824305 | SARC | Male-baised eQTL |
| rs11525347 | chr11:4404713:C:T | - | 0.123581812670537 | 0.0122948035118099 | SARC | Male-baised eQTL |
| rs115835703 | chr11:4404721:G:C | - | 0.123581812670537 | 0.0122948035118099 | SARC | Male-baised eQTL |
| rs116222841 | chr11:4404726:C:T | - | 0.123581812670537 | 0.0122948035118099 | SARC | Male-baised eQTL |
| rs11529912 | chr11:4401703:G:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11529915 | chr11:4401929:G:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11529916 | chr11:4401978:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs117621194 | chr11:4403500:A:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs145404414 | chr11:4403576:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs7949731 | chr11:4403849:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs7932344 | chr11:4404036:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11529269 | chr11:4404357:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11529922 | chr11:4404380:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs151063244 | chr11:4404465:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs76307234 | chr11:4404612:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs146333090 | chr11:4404641:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs145933372 | chr11:4404984:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs114952416 | chr11:4404989:T:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs34666651 | chr11:4405527:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs35831442 | chr11:4405598:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11529923 | chr11:4406065:G:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032151 | chr11:4406363:G:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12295815 | chr11:4406428:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032152 | chr11:4406514:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11529929 | chr11:4406560:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12806463 | chr11:4406643:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12808050 | chr11:4406790:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12790080 | chr11:4406823:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12806701 | chr11:4406824:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12789880 | chr11:4406916:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12789338 | chr11:4406958:C:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12790052 | chr11:4406975:A:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs115627351 | chr11:4407256:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs143206092 | chr11:4407420:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs141692595 | chr11:4407426:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs74443868 | chr11:4407537:C:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs74680006 | chr11:4407593:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs74986693 | chr11:4407597:C:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs79271861 | chr11:4407655:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs117330444 | chr11:4407753:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032167 | chr11:4407854:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032168 | chr11:4407886:C:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032169 | chr11:4407892:G:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs4495886 | chr11:4408002:C:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs4495887 | chr11:4408062:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032174 | chr11:4408467:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032177 | chr11:4408702:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032182 | chr11:4408960:G:A | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs11032183 | chr11:4409088:C:T | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs10836030 | chr11:4409277:A:G | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs10836031 | chr11:4409428:T:C | - | 0.121100541579897 | 0.0139563169065814 | SARC | Male-baised eQTL |
| rs12806300 | chr11:4406600:G:A | - | 0.122221123768119 | 0.0148775803998955 | SARC | Male-baised eQTL |
| rs2898958 | chr11:4405682:A:G | - | 0.121615927705456 | 0.0161382685358709 | SARC | Male-baised eQTL |
| rs7931371 | chr11:4403963:G:C | - | 0.119562290887556 | 0.0259268492907126 | SARC | Male-baised eQTL |
| rs71478795 | chr11:4405709:G:A | - | 0.127865476580334 | 0.0366421899496812 | SARC | Male-baised eQTL |
| rs12807664 | chr11:4406574:C:T | - | 0.114817794476923 | 0.0453317160508685 | SARC | Male-baised eQTL |
| rs12808340 | chr11:4406575:A:G | - | 0.114817794476923 | 0.0453317160508685 | SARC | Male-baised eQTL |
| rs7107711 | chr11:13233991:G:C | - | -0.0239708559746164 | 0.0261999593199447 | LUSC | Male-baised eQTL |
| rs7104311 | chr11:13232957:C:A | - | -0.0234812044932938 | 0.0418920092206128 | LUSC | Male-baised eQTL |
| rs2500055 | chr11:5068155:C:G | - | 0.0484395198476635 | 0.032863491058226 | BLCA | Male-baised eQTL |
| rs11021841 | chr11:11419067:C:G | - | -0.041546488461197 | 0.0478014785812362 | BLCA | Male-baised eQTL |
| rs11021830 | chr11:11398374:T:C | - | -0.0689556976089996 | 0.0478388689998817 | BLCA | Male-baised eQTL |
| rs10500970 | chr11:23900772:G:T | - | 0.0554711062490011 | 0.00283307452303091 | LUAD | Male-baised eQTL |
| rs78583779 | chr11:23913231:C:A | - | 0.0544175315695645 | 0.00320642433223571 | LUAD | Male-baised eQTL |
| rs201746053 | chr11:12335453:T:C | - | 0.05081525562513 | 0.00561608198346975 | LUAD | Male-baised eQTL |
| rs1596046 | chr11:13067641:G:A | - | 0.0460620124453683 | 0.0107737736200384 | LUAD | Male-baised eQTL |
| rs4501982 | chr11:23894014:T:A | - | -0.0467383562530252 | 0.0133593366065884 | LUAD | Male-baised eQTL |
| rs4757383 | chr11:12350362:T:A | - | -0.0450121309510025 | 0.0152958076464694 | LUAD | Male-baised eQTL |
| rs7930218 | chr11:10213165:G:T | - | -0.0415265070135254 | 0.0176558698771639 | LUAD | Male-baised eQTL |
| rs4757387 | chr11:12354605:T:C | - | -0.04462571739898 | 0.0179568132015498 | LUAD | Male-baised eQTL |
| rs111820833 | chr11:13086067:C:G | - | 0.0365837621404603 | 0.0273955898193201 | LUAD | Male-baised eQTL |
| rs150220755 | chr11:13088677:C:T | - | 0.0365766328472875 | 0.0276700946666448 | LUAD | Male-baised eQTL |
| rs10767129 | chr11:23892604:A:G | - | -0.0419954220517445 | 0.0293345545957879 | LUAD | Male-baised eQTL |
| rs79053957 | chr11:13073756:G:T | - | 0.0361392645356694 | 0.02975513851971 | LUAD | Male-baised eQTL |
| rs12805038 | chr11:13074713:G:C | - | 0.0361392645356694 | 0.02975513851971 | LUAD | Male-baised eQTL |
| rs74455840 | chr11:13078452:A:T | - | 0.0361392645356694 | 0.02975513851971 | LUAD | Male-baised eQTL |
| rs10734346 | chr11:23925908:T:G | - | -0.0404983213941473 | 0.0370837032399146 | LUAD | Male-baised eQTL |
| rs59849361 | chr11:13090517:T:G | - | 0.0346053743801286 | 0.0392023431432924 | LUAD | Male-baised eQTL |
| rs111748209 | chr11:13070451:C:G | - | 0.0384554670995052 | 0.0402420488424853 | LUAD | Male-baised eQTL |
| rs56306020 | chr11:13068208:G:C | - | 0.0372946121628146 | 0.0467742178828789 | LUAD | Male-baised eQTL |
| rs55768036 | chr11:13068220:A:G | - | 0.0372946121628146 | 0.0467742178828789 | LUAD | Male-baised eQTL |
| rs55982827 | chr11:13068437:A:G | - | 0.0372946121628146 | 0.0467742178828789 | LUAD | Male-baised eQTL |
| rs2403646 | chr11:20946852:T:A | - | -0.122853570410148 | 0.00778605979829806 | COAD | Male-baised eQTL |
| rs12807351 | chr11:4939520:C:T | - | 0.105646789258545 | 0.0117425495556663 | COAD | Male-baised eQTL |
| rs12807538 | chr11:4939613:C:T | - | 0.105646789258545 | 0.0117425495556663 | COAD | Male-baised eQTL |
| rs12808710 | chr11:4957078:C:G | - | 0.108735955122166 | 0.0180445526343841 | COAD | Male-baised eQTL |
| rs7945456 | chr11:4957347:T:C | - | 0.108735955122166 | 0.0180445526343841 | COAD | Male-baised eQTL |
| rs11602621 | chr11:4958203:A:G | - | 0.108735955122166 | 0.0180445526343841 | COAD | Male-baised eQTL |
| rs11600505 | chr11:4958267:C:T | - | 0.108735955122166 | 0.0180445526343841 | COAD | Male-baised eQTL |
| rs11600508 | chr11:4958320:C:T | - | 0.108735955122166 | 0.0180445526343841 | COAD | Male-baised eQTL |
| rs12791890 | chr11:4957839:A:G | - | 0.104890927693668 | 0.025284175320331 | COAD | Male-baised eQTL |
| rs12791258 | chr11:4957899:C:T | - | 0.104890927693668 | 0.025284175320331 | COAD | Male-baised eQTL |
| rs4910349 | chr11:11466368:T:C | - | 0.0936549589621083 | 0.0396883264150111 | COAD | Male-baised eQTL |
| rs2595996 | chr11:4942873:A:C | - | -0.0845428186270738 | 0.0427361206720575 | COAD | Male-baised eQTL |
| rs4420262 | chr11:21472137:T:C | - | -0.0958207468141324 | 0.0430036948785498 | COAD | Male-baised eQTL |
| rs201885883 | chr11:10174815:G:A | - | 0.11170595313506 | 0.0435794205453852 | COAD | Male-baised eQTL |
| rs199842512 | chr11:10174840:C:G | - | 0.11170595313506 | 0.0435794205453852 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000133818 |
| CpG Site: cg08498247 | |
| Position to Gene: gene | |
| Male Effect: -0.492844347089992 | |
| Female Effect: - | |
 | Gene ID: ENSG00000133818 |
| CpG Site: cg20007622 | |
| Position to Gene: gene | |
| Male Effect: -0.492734518578812 | |
| Female Effect: - | |
 | Gene ID: ENSG00000133818 |
| CpG Site: cg19336497 | |
| Position to Gene: gene | |
| Male Effect: -0.246507857943761 | |
| Female Effect: - | |
 | Gene ID: ENSG00000133818 |
| CpG Site: cg06127541 | |
| Position to Gene: gene | |
| Male Effect: -0.172250586477518 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg08498247 | chr11:14361209 | gene | -0.492844347089992 | 9.91470640670502e-191 | -0.9914242013162345 | 2.614555532352696e-197 | LUAD |
| cg20007622 | chr11:14319046 | gene | -0.492734518578812 | 6.25048670400759e-189 | -0.9923896665626268 | 6.79146485193772e-184 | LUAD |
| cg19336497 | chr11:14359453 | gene | -0.246507857943761 | 7.41097656095815e-30 | -0.7010809858544014 | 2.662380003025312e-34 | LUAD |
| cg06127541 | chr11:14310055 | gene | -0.172250586477518 | 5.4808882680782e-18 | -0.565349346780083 | 3.104108745574514e-20 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of RRAS2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000133818 | RRAS2 | C0019207 | Hepatoma, Morris | 1 | CTD_human |
| ENSG00000133818 | RRAS2 | C0019208 | Hepatoma, Novikoff | 1 | CTD_human |
| ENSG00000133818 | RRAS2 | C0023904 | Liver Neoplasms, Experimental | 1 | CTD_human |
| ENSG00000133818 | RRAS2 | C0086404 | Experimental Hepatoma | 1 | CTD_human |
| ENSG00000133818 | RRAS2 | C0349639 | Juvenile Myelomonocytic Leukemia | 1 | CTD_human |
