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Gene: ENSG00000133636 |
Summary for NTS |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000133636 | Gene symbol | NTS |
| Gene name | neurotensin | |
| HGNC | 8038 | |
| Entrez ID | 4922 | |
| Gene type | protein_coding | |
| Synonyms | NTS| | |
| UniProtAcc | P30990 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for NTS |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| NTS | 1.38e+02 | -5.23e+00 | 1.19e+00 | -4.38e+00 | 1.17e-05 | 4.04e-04 | BRCA |
| NTS | 4.64e+02 | 2.42e+00 | 2.83e-01 | 8.54e+00 | 1.36e-17 | 6.40e-15 | LUAD |
| NTS | 1.52e+01 | -1.03e+00 | 2.62e-01 | -3.92e+00 | 8.68e-05 | 7.25e-03 | LGG |
| NTS | 2.56e+03 | 2.13e+00 | 3.52e-01 | 6.05e+00 | 1.45e-09 | 2.02e-07 | HNSC |
| NTS | 5.68e+01 | 1.59e+00 | 2.71e-01 | 5.89e+00 | 3.96e-09 | 1.86e-06 | COAD |
| NTS | 1.04e+02 | -2.07e+00 | 2.91e-01 | -7.09e+00 | 1.32e-12 | 7.89e-10 | BLCA |
| NTS | 1.84e+02 | -2.24e+00 | 2.67e-01 | -8.37e+00 | 5.69e-17 | 4.54e-14 | STAD |
| NTS | 3.32e+03 | 2.62e+00 | 7.36e-01 | 3.56e+00 | 3.75e-04 | 3.54e-02 | ESCA |
| NTS | 3.09e+02 | -3.64e+00 | 7.77e-01 | -4.69e+00 | 2.78e-06 | 4.96e-04 | ACC |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| NTS | 9.06e+01 | -1.02e+00 | 2.91e-01 | -3.51e+00 | 4.53e-04 | 7.24e-04 | KIRC |
| NTS | 3.01e+03 | 2.70e+00 | 6.40e-01 | 4.20e+00 | 2.30e-05 | 6.90e-05 | HNSC |
| NTS | 3.46e+03 | 6.44e+00 | 1.22e+00 | 5.29e+00 | 1.23e-07 | 4.15e-06 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for NTS |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for NTS |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| SARC | cg04916911 | chr12:85874376 | CGI:chr12:85280100-85280922 | UTR,promoter,exon,gene body | 2.72e-01 | 1.71e-01 | 2.78e+00 | 5.43e-03 | 1.22e-02 | 1.02e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg08888956 | chr12:85874061 | CGI:chr12:85280100-85280922 | promoter | 2.30e-01 | 4.03e-01 | -5.88e+00 | 4.07e-09 | 3.88e-08 | -1.73e-01 |
| CHOL | cg08888956 | chr12:85874061 | CGI:chr12:85280100-85280922 | promoter | 6.62e-01 | 4.17e-01 | 2.88e+00 | 4.04e-03 | 1.47e-02 | 2.45e-01 |
| CHOL | cg04916911 | chr12:85874376 | CGI:chr12:85280100-85280922 | UTR,promoter,exon,gene body | 4.71e-01 | 1.55e-01 | 2.58e+00 | 9.87e-03 | 2.15e-02 | 3.16e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for NTS |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for NTS |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for NTS |
| TFs related to NTS. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | ZNF235 | NTS | 2.82e+00 | 4.42e-03 | 4.29e+00 | 9.81e-01 | Female-biased |
| CHOL | BHLHE22 | NTS | 5.80e+00 | 9.81e-01 | 4.96e+00 | 1.76e-02 | Male-biased |
| CHOL | DMRT2 | NTS | 5.01e+00 | 9.94e-01 | 3.79e+00 | 3.91e-03 | Male-biased |
| CHOL | EN1 | NTS | 5.30e+00 | 9.88e-01 | 4.33e+00 | 1.04e-02 | Male-biased |
| CHOL | HOXB7 | NTS | 4.86e+00 | 9.90e-01 | 3.80e+00 | 7.34e-03 | Male-biased |
| CHOL | HOXB8 | NTS | 5.11e+00 | 9.88e-01 | 4.11e+00 | 9.45e-03 | Male-biased |
| CHOL | NEUROD1 | NTS | 5.23e+00 | 9.91e-01 | 4.17e+00 | 7.13e-03 | Male-biased |
| CHOL | NEUROG1 | NTS | 6.22e+00 | 9.81e-01 | 5.40e+00 | 1.83e-02 | Male-biased |
| CHOL | NEUROG2 | NTS | 6.10e+00 | 9.80e-01 | 5.28e+00 | 1.90e-02 | Male-biased |
| CHOL | ONECUT3 | NTS | 4.91e+00 | 9.93e-01 | 3.69e+00 | 3.87e-03 | Male-biased |
| CHOL | SOX18 | NTS | 4.93e+00 | 9.91e-01 | 3.84e+00 | 6.37e-03 | Male-biased |
| CHOL | SOX5 | NTS | 5.26e+00 | 9.84e-01 | 4.38e+00 | 1.46e-02 | Male-biased |
| CHOL | TBX19 | NTS | 5.73e+00 | 9.83e-01 | 4.86e+00 | 1.56e-02 | Male-biased |
| CHOL | TEAD1 | NTS | 4.61e+00 | 9.83e-01 | 3.69e+00 | 1.24e-02 | Male-biased |
| CHOL | ZNF334 | NTS | 4.13e+00 | 9.88e-01 | 2.82e+00 | 2.48e-03 | Male-biased |
| CHOL | ZNF35 | NTS | 4.23e+00 | 9.87e-01 | 3.07e+00 | 4.65e-03 | Male-biased |
| CHOL | ZNF584 | NTS | 4.44e+00 | 9.87e-01 | 3.38e+00 | 7.07e-03 | Male-biased |
| CHOL | ZNF79 | NTS | 4.05e+00 | 9.85e-01 | 2.87e+00 | 4.14e-03 | Male-biased |
| MESO | DMRT2 | NTS | 4.82e+00 | 9.82e-01 | 3.71e+00 | 1.35e-02 | Male-biased |
| MESO | ZNF334 | NTS | 3.99e+00 | 9.82e-01 | 2.42e+00 | 2.75e-03 | Male-biased |
| MESO | ZNF35 | NTS | 4.07e+00 | 9.81e-01 | 2.72e+00 | 6.05e-03 | Male-biased |
| PCPG | DMRT2 | NTS | 4.85e+00 | 9.92e-01 | 3.83e+00 | 3.74e-03 | Male-biased |
| PCPG | EN1 | NTS | 5.20e+00 | 9.86e-01 | 4.42e+00 | 1.15e-02 | Male-biased |
| PCPG | HOXB7 | NTS | 4.66e+00 | 9.82e-01 | 3.90e+00 | 1.20e-02 | Male-biased |
| PCPG | HOXB8 | NTS | 4.82e+00 | 9.82e-01 | 4.09e+00 | 1.40e-02 | Male-biased |
| PCPG | HSF5 | NTS | 5.64e+00 | 9.82e-01 | 4.94e+00 | 1.66e-02 | Male-biased |
| PCPG | NEUROD1 | NTS | 5.10e+00 | 9.83e-01 | 4.38e+00 | 1.46e-02 | Male-biased |
| PCPG | ONECUT3 | NTS | 4.73e+00 | 9.87e-01 | 3.86e+00 | 7.60e-03 | Male-biased |
| PCPG | SOX18 | NTS | 4.56e+00 | 9.85e-01 | 3.73e+00 | 8.73e-03 | Male-biased |
| PCPG | SOX5 | NTS | 5.13e+00 | 9.85e-01 | 4.38e+00 | 1.24e-02 | Male-biased |
| PCPG | ZNF584 | NTS | 4.18e+00 | 9.81e-01 | 3.29e+00 | 6.55e-03 | Male-biased |
| NTS related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for NTS |
| RBPs related to ES in NTS. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| NTS related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000133636 | FZD10-AS1,hsa-mir-202,NTS | Male-specific ceRNA | TCGA-KIRP |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12300367 | chr12:77823857:A:G | - | 0.204840470989746 | 0.00449910463476449 | READ | Female-baised eQTL |
| rs1703098 | chr12:82893747:T:A | - | 0.243348671205339 | 2.87445862751193e-07 | PAAD | Female-baised eQTL |
| rs10777302 | chr12:91415664:A:G | - | -0.204714014633227 | 3.63362805971608e-05 | PAAD | Female-baised eQTL |
| rs11114165 | chr12:79545569:C:G | - | 0.177383205071686 | 0.000815629753625966 | PAAD | Female-baised eQTL |
| rs12300306 | chr12:79555853:A:G | - | 0.177383205071686 | 0.000815629753625966 | PAAD | Female-baised eQTL |
| rs75460553 | chr12:75894845:G:A | - | 0.184069321461318 | 0.0016360574860527 | PAAD | Female-baised eQTL |
| rs2491339 | chr12:79713113:T:G | - | 0.170006391015775 | 0.00199326202459369 | PAAD | Female-baised eQTL |
| rs6539473 | chr12:79769834:T:C | - | 0.180608510350533 | 0.00243273506397431 | PAAD | Female-baised eQTL |
| rs2369464 | chr12:77040908:A:C | - | 0.16735801794418 | 0.00276779915393238 | PAAD | Female-baised eQTL |
| rs7302437 | chr12:85896084:C:T | - | 0.159915001233118 | 0.00418003998544343 | PAAD | Female-baised eQTL |
| rs73378166 | chr12:85896488:T:A | - | 0.159915001233118 | 0.00418003998544343 | PAAD | Female-baised eQTL |
| rs1379921 | chr12:91378580:T:C | - | -0.148327164730299 | 0.00720559231990735 | PAAD | Female-baised eQTL |
| rs7310696 | chr12:91387543:C:T | - | -0.148327164730299 | 0.00720559231990735 | PAAD | Female-baised eQTL |
| rs2131383 | chr12:91395879:C:G | - | -0.148327164730299 | 0.00720559231990735 | PAAD | Female-baised eQTL |
| rs1492945 | chr12:91403615:T:C | - | -0.148327164730299 | 0.00720559231990735 | PAAD | Female-baised eQTL |
| rs6539472 | chr12:79769748:G:A | - | 0.165885893029342 | 0.00755700184107935 | PAAD | Female-baised eQTL |
| rs7952872 | chr12:79752068:C:A | - | -0.165744371490753 | 0.0077971348269381 | PAAD | Female-baised eQTL |
| rs2998416 | chr12:79753236:A:G | - | -0.165744371490753 | 0.0077971348269381 | PAAD | Female-baised eQTL |
| rs7134915 | chr12:85928195:C:A | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117109 | chr12:85929201:C:T | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs7960313 | chr12:85929477:C:T | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs2044618 | chr12:85930652:A:C | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs2044619 | chr12:85930798:A:G | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117112 | chr12:85935074:T:C | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117117 | chr12:85939408:G:T | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs10863117 | chr12:85941664:C:A | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117121 | chr12:85943003:A:C | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117123 | chr12:85943994:A:G | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs10863119 | chr12:85947304:G:A | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117125 | chr12:85948402:T:C | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs1448093 | chr12:85949597:T:C | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs1584367 | chr12:85950363:G:T | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs11117128 | chr12:85954094:G:A | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs75879590 | chr12:85954754:G:T | - | 0.149618438058293 | 0.00934413671512895 | PAAD | Female-baised eQTL |
| rs7294874 | chr12:77143985:A:C | - | 0.145346134611914 | 0.0102475265293986 | PAAD | Female-baised eQTL |
| rs7301204 | chr12:82852353:G:C | - | 0.133344874619777 | 0.0156015990608614 | PAAD | Female-baised eQTL |
| rs2491342 | chr12:79761594:T:C | - | -0.153315234154838 | 0.0177671558699337 | PAAD | Female-baised eQTL |
| rs7135958 | chr12:88539967:G:T | - | -0.140973940254523 | 0.0179793509600677 | PAAD | Female-baised eQTL |
| rs3782176 | chr12:88545356:A:G | - | -0.140973940254523 | 0.0179793509600677 | PAAD | Female-baised eQTL |
| rs1492347 | chr12:88532196:T:C | - | -0.141090097596698 | 0.0185212923631679 | PAAD | Female-baised eQTL |
| rs4083220 | chr12:79701402:C:T | - | 0.135929785884999 | 0.0219695254472751 | PAAD | Female-baised eQTL |
| rs7136806 | chr12:79709990:A:C | - | 0.135889983054688 | 0.0224278328250439 | PAAD | Female-baised eQTL |
| rs2463171 | chr12:79712543:G:A | - | 0.135889983054688 | 0.0224278328250439 | PAAD | Female-baised eQTL |
| rs7969188 | chr12:88530290:C:G | - | -0.133149193481015 | 0.0306787968880248 | PAAD | Female-baised eQTL |
| rs7964695 | chr12:88541852:G:T | - | -0.133149193481015 | 0.0306787968880248 | PAAD | Female-baised eQTL |
| rs3995243 | chr12:79705130:T:C | - | 0.12826969036142 | 0.0366886793540504 | PAAD | Female-baised eQTL |
| rs17019660 | chr12:91879162:A:T | - | 0.116153375179236 | 0.0397817913976433 | PAAD | Female-baised eQTL |
| rs12309087 | chr12:94759582:T:C | - | 0.124290549447129 | 0.0447886404929473 | PAAD | Female-baised eQTL |
| rs10777125 | chr12:88522058:G:A | - | -0.126707770149107 | 0.0464719161527035 | PAAD | Female-baised eQTL |
| rs79032164 | chr12:92501435:G:A | - | 0.200202275167201 | 0.0331384053974358 | HNSC | Female-baised eQTL |
| rs12227617 | chr12:83458765:C:T | - | 0.154127345430369 | 0.0135233662307884 | LIHC | Female-baised eQTL |
| rs11115745 | chr12:83349677:C:A | - | 0.142756085351992 | 0.0279845181015766 | LIHC | Female-baised eQTL |
| rs11115746 | chr12:83353367:C:T | - | 0.142756085351992 | 0.0279845181015766 | LIHC | Female-baised eQTL |
| rs12230326 | chr12:83446319:C:A | - | 0.142687554818433 | 0.0283411183520984 | LIHC | Female-baised eQTL |
| rs2248356 | chr12:92900209:T:A | - | -0.122220611643783 | 0.000287892645571927 | STAD | Female-baised eQTL |
| rs71452175 | chr12:87268828:C:T | - | 0.0811823916102409 | 0.0249948408788247 | STAD | Female-baised eQTL |
| rs71452181 | chr12:87297868:G:A | - | 0.0758981830992337 | 0.0424415406833525 | STAD | Female-baised eQTL |
| rs7302170 | chr12:81096803:T:C | - | 0.141994012628843 | 0.0463113773134695 | STAD | Female-baised eQTL |
| rs78711843 | chr12:95798998:A:G | - | 0.0597478452495449 | 6.2590807522418e-05 | LUAD | Female-baised eQTL |
| rs2131383 | chr12:91395879:C:G | - | -0.0406705118732754 | 0.00520391077638968 | LUAD | Female-baised eQTL |
| rs11610271 | chr12:87526445:C:T | - | 0.029654069411341 | 0.0475420563362416 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2056331 | chr12:89659578:T:C | - | -0.181884833156254 | 1.59650593486452e-05 | READ | Male-baised eQTL |
| rs11115444 | chr12:82820939:G:A | - | 0.124241812785574 | 0.0127906557817143 | PAAD | Male-baised eQTL |
| rs10862513 | chr12:82820396:A:G | - | 0.117999308427648 | 0.021557881036599 | PAAD | Male-baised eQTL |
| rs10862512 | chr12:82812563:T:C | - | 0.112270784748863 | 0.0344091394212436 | PAAD | Male-baised eQTL |
| rs11115434 | chr12:82806414:C:T | - | 0.112454976686295 | 0.0345738578864145 | PAAD | Male-baised eQTL |
| rs201335759 | chr12:80270058:A:C | - | 0.0815918836095369 | 0.00777315657939379 | LUAD | Male-baised eQTL |
| rs17195772 | chr12:77831406:C:A | - | 0.0388165697720299 | 0.0421965601304784 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000133636 |
| CpG Site: cg08888956 | |
| Position to Gene: promoter | |
| Male Effect: -0.162188746997926 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg08888956 | chr12:85874061 | promoter | -0.162188746997926 | 4.95446389723e-09 | -0.44104476141167637 | 4.96671094181897e-12 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of NTS |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000133636 | NTS | C0001973 | Alcoholic Intoxication, Chronic | 2 | PSYGENET |
| ENSG00000133636 | NTS | C0007370 | Catalepsy | 1 | CTD_human |
| ENSG00000133636 | NTS | C0011570 | Mental Depression | 1 | PSYGENET |
| ENSG00000133636 | NTS | C0011581 | Depressive disorder | 1 | PSYGENET |
| ENSG00000133636 | NTS | C0026837 | Muscle Rigidity | 1 | CTD_human |
| ENSG00000133636 | NTS | C0036341 | Schizophrenia | 4 | PSYGENET |
| ENSG00000133636 | NTS | C0151564 | Cogwheel Rigidity | 1 | CTD_human |
| ENSG00000133636 | NTS | C0231519 | Gegenhalten | 1 | CTD_human |
| ENSG00000133636 | NTS | C0233608 | Catatonic Rigidity | 1 | CTD_human |
| ENSG00000133636 | NTS | C0233612 | Waxy flexibility | 1 | CTD_human |
| ENSG00000133636 | NTS | C0239325 | Extensor Rigidity | 1 | CTD_human |
| ENSG00000133636 | NTS | C0277821 | Extrapyramidal Rigidity | 1 | CTD_human |
| ENSG00000133636 | NTS | C0428977 | Bradycardia | 1 | CTD_human |
| ENSG00000133636 | NTS | C0525045 | Mood Disorders | 1 | PSYGENET |
| ENSG00000133636 | NTS | C0751217 | Hyperkinesia, Generalized | 2 | CTD_human |
| ENSG00000133636 | NTS | C1320474 | Nuchal Rigidity | 1 | CTD_human |
| ENSG00000133636 | NTS | C3887506 | Hyperkinesia | 2 | CTD_human |
