|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000130511 |
Summary for SSBP4 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000130511 | Gene symbol | SSBP4 |
| Gene name | single stranded DNA binding protein 4 | |
| HGNC | 15676 | |
| Entrez ID | 170463 | |
| Gene type | protein_coding | |
| Synonyms | SSBP4| | |
| UniProtAcc | Q9BWG4 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SSBP4 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SSBP4 | 1.95e+03 | 1.02e+00 | 1.03e-01 | 9.87e+00 | 5.79e-23 | 3.33e-22 | KIRC |
| SSBP4 | 3.28e+03 | 1.12e+00 | 1.54e-01 | 7.31e+00 | 2.69e-13 | 5.75e-12 | THCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SSBP4 | 1.85e+03 | 1.00e+00 | 1.65e-01 | 6.07e+00 | 1.25e-09 | 6.42e-09 | COAD |
| SSBP4 | 2.56e+03 | 1.36e+00 | 3.20e-01 | 4.26e+00 | 2.07e-05 | 1.23e-04 | READ |
Top |
Sex-biased somatic mutation for SSBP4 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SSBP4 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg11778563 | chr19:18420543 | CGI:chr19:18416841-18420308 | promoter,gene body | 2.68e-01 | 1.62e-01 | 2.38e+00 | 1.74e-02 | 2.13e-02 | 1.06e-01 |
| BLCA | cg09516349 | chr19:18418529 | CGI:chr19:18416841-18420308 | promoter | 2.18e-01 | 3.56e-01 | -3.92e+00 | 8.69e-05 | 3.62e-04 | -1.39e-01 |
| BLCA | cg11778563 | chr19:18420543 | CGI:chr19:18416841-18420308 | promoter,gene body | 1.81e-01 | 3.29e-01 | -4.16e+00 | 3.19e-05 | 1.85e-04 | -1.49e-01 |
| KIRP | cg11778563 | chr19:18420543 | CGI:chr19:18416841-18420308 | promoter,gene body | 4.53e-01 | 3.29e-01 | 2.33e+00 | 1.97e-02 | 2.28e-02 | 1.24e-01 |
| CHOL | cg09529667 | chr19:18420301 | CGI:chr19:18416841-18420308 | promoter,gene body | 1.84e-01 | 4.96e-01 | -3.10e+00 | 1.96e-03 | 1.07e-02 | -3.12e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| COAD | cg00751072 | chr19:18418311 | CGI:chr19:18416841-18420308 | promoter | 3.47e-01 | 2.35e-01 | 3.78e+00 | 1.59e-04 | 8.69e-04 | 1.11e-01 |
| LIHC | cg09529667 | chr19:18420301 | CGI:chr19:18416841-18420308 | promoter,gene body | 3.65e-01 | 5.16e-01 | -2.90e+00 | 3.75e-03 | 6.40e-03 | -1.51e-01 |
Top |
Exon skipping events with PSI in TCGA for SSBP4 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| KIRC | exon_skip_303809 | 3.83e-01 | 2.62e-01 | 7.14e+00 | 9.54e-13 | 2.98e-11 | 1.21e-01 |
| THCA | exon_skip_303809 | 3.37e-01 | 2.25e-01 | 4.88e+00 | 1.06e-06 | 3.58e-05 | 1.12e-01 |
| BLCA | exon_skip_303809 | 4.26e-01 | 2.70e-01 | 3.52e+00 | 4.29e-04 | 3.62e-03 | 1.55e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_303809 | 4.33e-01 | 2.84e-01 | 1.17e+01 | 1.36e-31 | 8.65e-30 | 1.49e-01 |
Top |
RNA A-to-I editing events in TCGA for SSBP4 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for SSBP4 |
| TFs related to SSBP4. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LAML | PLAGL2 | SSBP4 | 4.89e+00 | 9.91e-01 | 3.74e+00 | 4.15e-03 | Male-biased |
| LAML | ZIC2 | SSBP4 | 4.21e+00 | 9.82e-01 | 3.10e+00 | 4.50e-03 | Male-biased |
| LAML | ZNF101 | SSBP4 | 4.35e+00 | 9.81e-01 | 3.39e+00 | 8.14e-03 | Male-biased |
| LAML | ZNF331 | SSBP4 | 4.31e+00 | 9.82e-01 | 3.28e+00 | 6.30e-03 | Male-biased |
| LAML | ZNF692 | SSBP4 | 4.54e+00 | 9.86e-01 | 3.50e+00 | 6.00e-03 | Male-biased |
| SSBP4 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SSBP4 |
| RBPs related to ES in SSBP4. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | ESRP2 | exon_skip_303805 | 8.37e+00 | 1.08e-02 | 8.72e+00 | 9.84e-01 | Female-biased |
| THYM | SNRPA | exon_skip_303822 | 8.88e+00 | 9.87e-01 | 8.54e+00 | 7.65e-03 | Male-biased |
| LIHC | SAMD4A | exon_skip_303819 | 8.37e+00 | 1.14e-02 | 8.74e+00 | 9.83e-01 | Female-biased |
| DLBC | ESRP2 | exon_skip_303804 | 8.72e+00 | 9.89e-01 | 8.33e+00 | 5.44e-03 | Male-biased |
| LUAD | YB-1 | exon_skip_303801 | 9.15e+00 | 7.71e-03 | 9.51e+00 | 9.90e-01 | Female-biased |
| KIRP | SAMD4A | exon_skip_303820 | 8.18e+00 | 1.09e-02 | 8.50e+00 | 9.82e-01 | Female-biased |
| BRCA | SAMD4A | exon_skip_303819 | 8.07e+00 | 3.34e-03 | 9.03e+00 | 9.92e-01 | Female-biased |
| READ | SAMD4A | exon_skip_303819 | 8.72e+00 | 9.93e-01 | 8.18e+00 | 1.29e-03 | Male-biased |
| PCPG | ESRP2 | exon_skip_303804 | 8.68e+00 | 9.93e-01 | 8.20e+00 | 1.68e-03 | Male-biased |
| MESO | SAMD4A | exon_skip_303820 | 8.51e+00 | 9.85e-01 | 8.14e+00 | 8.19e-03 | Male-biased |
| GBM | SAMD4A | exon_skip_303819 | 8.83e+00 | 9.93e-01 | 8.34e+00 | 2.14e-03 | Male-biased |
| SKCM | SAMD4A | exon_skip_303819 | 8.28e+00 | 2.19e-03 | 8.80e+00 | 9.93e-01 | Female-biased |
| HNSC | SAMD4A | exon_skip_303820 | 8.18e+00 | 1.11e-02 | 8.51e+00 | 9.82e-01 | Female-biased |
| SSBP4 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs797876 | chr19:23533739:C:T | - | 0.0500243083029393 | 0.0205584628565832 | THCA | Female-baised eQTL |
| rs6511253 | chr19:21495996:T:C | - | 0.0623341787320257 | 0.0468523576798093 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs3867196 | chr19:20832327:G:T | - | 0.0563271017709795 | 0.0077884749826775 | LGG | Male-baised eQTL |
| rs4389267 | chr19:20798431:C:G | - | 0.0548358051506404 | 0.0130112416255606 | LGG | Male-baised eQTL |
| rs143395297 | chr19:20854969:G:A | - | 0.0544151902932358 | 0.0141590658457064 | LGG | Male-baised eQTL |
| rs11085394 | chr19:20841053:A:G | - | 0.0543501599712953 | 0.0144377600059507 | LGG | Male-baised eQTL |
| rs11085386 | chr19:20805007:T:G | - | 0.0543209856908503 | 0.01463467518187 | LGG | Male-baised eQTL |
| rs12459192 | chr19:20796498:G:C | - | 0.0542362502072898 | 0.014970471982028 | LGG | Male-baised eQTL |
| rs12976216 | chr19:20800017:A:G | - | 0.0542362502072898 | 0.014970471982028 | LGG | Male-baised eQTL |
| rs6511166 | chr19:20807995:G:A | - | 0.0542362502072898 | 0.014970471982028 | LGG | Male-baised eQTL |
| rs7251364 | chr19:20821809:G:A | - | 0.0539387051098728 | 0.0170413764939718 | LGG | Male-baised eQTL |
| rs8104485 | chr19:20921640:T:G | - | 0.0538979344884885 | 0.0173786758956206 | LGG | Male-baised eQTL |
| rs7249876 | chr19:20906050:G:A | - | 0.053782357430007 | 0.0179142518492647 | LGG | Male-baised eQTL |
| rs12610750 | chr19:20947477:G:A | - | 0.0544280094894304 | 0.0180198973474039 | LGG | Male-baised eQTL |
| rs12611073 | chr19:20947709:G:A | - | 0.0542881081685649 | 0.0187338323203985 | LGG | Male-baised eQTL |
| rs8107262 | chr19:20880465:T:G | - | 0.0536364691885995 | 0.0187417521336061 | LGG | Male-baised eQTL |
| rs2081049 | chr19:20932796:A:C | - | 0.053896979987558 | 0.0194937376205027 | LGG | Male-baised eQTL |
| rs11670561 | chr19:20937009:T:A | - | 0.053896979987558 | 0.0194937376205027 | LGG | Male-baised eQTL |
| rs11669368 | chr19:20917426:C:A | - | 0.0535043260472067 | 0.0195369502644517 | LGG | Male-baised eQTL |
| rs7246544 | chr19:20869648:G:T | - | 0.0534855039470122 | 0.0195724115783329 | LGG | Male-baised eQTL |
| rs12983551 | chr19:20942904:T:A | - | 0.0540907044188266 | 0.0198907830495466 | LGG | Male-baised eQTL |
| rs4305208 | chr19:20895522:C:T | - | 0.0533897924872861 | 0.0201305505348622 | LGG | Male-baised eQTL |
| rs12978510 | chr19:20896894:G:T | - | 0.0533897924872861 | 0.0201305505348622 | LGG | Male-baised eQTL |
| rs12459251 | chr19:20899797:T:C | - | 0.0533897924872861 | 0.0201305505348622 | LGG | Male-baised eQTL |
| rs12971543 | chr19:20905134:C:A | - | 0.0533897924872861 | 0.0201305505348622 | LGG | Male-baised eQTL |
| rs62123243 | chr19:20908384:C:T | - | 0.0533897924872861 | 0.0201305505348622 | LGG | Male-baised eQTL |
| rs11667236 | chr19:20909778:C:T | - | 0.0533897924872861 | 0.0201305505348622 | LGG | Male-baised eQTL |
| rs8104353 | chr19:20922291:A:G | - | 0.0535081642456716 | 0.0203064582348762 | LGG | Male-baised eQTL |
| rs8109293 | chr19:20826464:A:G | - | 0.0533602598776008 | 0.0207632046947872 | LGG | Male-baised eQTL |
| rs11665919 | chr19:20831153:C:T | - | 0.0533602598776008 | 0.0207632046947872 | LGG | Male-baised eQTL |
| rs56397942 | chr19:20833520:C:T | - | 0.0533602598776008 | 0.0207632046947872 | LGG | Male-baised eQTL |
| rs4026063 | chr19:20834532:C:A | - | 0.0533482286585862 | 0.0208942824420244 | LGG | Male-baised eQTL |
| rs12971562 | chr19:20896540:G:A | - | 0.0532373995605199 | 0.0210205884782598 | LGG | Male-baised eQTL |
| rs3926977 | chr19:20795457:T:G | - | 0.0536846802960668 | 0.0212278883084886 | LGG | Male-baised eQTL |
| rs8108531 | chr19:20855920:A:G | - | 0.0530830562120891 | 0.0225582645617616 | LGG | Male-baised eQTL |
| rs35932444 | chr19:20858005:T:C | - | 0.0530830562120891 | 0.0225582645617616 | LGG | Male-baised eQTL |
| rs142880590 | chr19:20854914:C:T | - | 0.0530621155929298 | 0.0226382704322926 | LGG | Male-baised eQTL |
| rs7252076 | chr19:20864439:G:A | - | 0.0530628315640972 | 0.0227089930553492 | LGG | Male-baised eQTL |
| rs8107954 | chr19:20838267:G:A | - | 0.0530161609353942 | 0.0229195393714962 | LGG | Male-baised eQTL |
| rs12609663 | chr19:20839319:A:C | - | 0.0530161609353942 | 0.0229195393714962 | LGG | Male-baised eQTL |
| rs140121583 | chr19:20844367:T:C | - | 0.0530161609353942 | 0.0229195393714962 | LGG | Male-baised eQTL |
| rs8103666 | chr19:20853028:C:T | - | 0.0530161609353942 | 0.0229195393714962 | LGG | Male-baised eQTL |
| rs4572530 | chr19:20844867:A:G | - | 0.0529998152659194 | 0.0229903243721936 | LGG | Male-baised eQTL |
| rs75542420 | chr19:20845182:G:A | - | 0.0529998152659194 | 0.0229903243721936 | LGG | Male-baised eQTL |
| rs12981899 | chr19:20847861:C:G | - | 0.0529998152659194 | 0.0229903243721936 | LGG | Male-baised eQTL |
| rs12982816 | chr19:20804234:T:G | - | 0.0529694373411628 | 0.0232843356872324 | LGG | Male-baised eQTL |
| rs11669934 | chr19:20804777:A:G | - | 0.0529694373411628 | 0.0232843356872324 | LGG | Male-baised eQTL |
| rs12985971 | chr19:20919271:C:T | - | 0.0518026053490517 | 0.0242532744128631 | LGG | Male-baised eQTL |
| rs6511163 | chr19:20805831:G:A | - | 0.0526661367616498 | 0.025369814976368 | LGG | Male-baised eQTL |
| rs12976450 | chr19:20800121:A:T | - | 0.0525810679313278 | 0.0258810149094736 | LGG | Male-baised eQTL |
| rs8111693 | chr19:20957078:G:A | - | 0.052909897771668 | 0.0263781831102444 | LGG | Male-baised eQTL |
| rs35001426 | chr19:20862358:T:C | - | 0.0513391049365341 | 0.0285693359177615 | LGG | Male-baised eQTL |
| rs1985021 | chr19:20964704:T:C | - | 0.0524210263169664 | 0.030022939423658 | LGG | Male-baised eQTL |
| rs7254728 | chr19:20965376:A:C | - | 0.0524210263169664 | 0.030022939423658 | LGG | Male-baised eQTL |
| rs8101800 | chr19:20917573:C:T | - | 0.0506219455639371 | 0.0336717361192257 | LGG | Male-baised eQTL |
| rs28802381 | chr19:20918564:A:G | - | 0.0506219455639371 | 0.0336717361192257 | LGG | Male-baised eQTL |
| rs7256412 | chr19:20881236:C:T | - | 0.0506170368266261 | 0.0336867704054197 | LGG | Male-baised eQTL |
| rs12104419 | chr19:20886725:T:C | - | 0.0506170368266261 | 0.0336867704054197 | LGG | Male-baised eQTL |
| rs12610256 | chr19:20909545:T:G | - | 0.0505648977785161 | 0.0341774114597257 | LGG | Male-baised eQTL |
| rs4809116 | chr19:20874241:C:G | - | 0.0510744097082009 | 0.0346217283044929 | LGG | Male-baised eQTL |
| rs7257679 | chr19:20948240:G:A | - | 0.0509977444758415 | 0.0360302270706408 | LGG | Male-baised eQTL |
| rs10422656 | chr19:20926804:G:A | - | 0.0506560766521116 | 0.0373973263618127 | LGG | Male-baised eQTL |
| rs10416168 | chr19:20926373:A:C | - | 0.0506444774896541 | 0.0374856982378973 | LGG | Male-baised eQTL |
| rs8109634 | chr19:20865062:G:C | - | 0.0502447227240676 | 0.0385831318976403 | LGG | Male-baised eQTL |
| rs7257856 | chr19:20781265:C:T | - | 0.050691464705151 | 0.0408019714390841 | LGG | Male-baised eQTL |
| rs34919365 | chr19:20782033:C:A | - | 0.050691464705151 | 0.0408019714390841 | LGG | Male-baised eQTL |
| rs8102160 | chr19:20782427:T:C | - | 0.050691464705151 | 0.0408019714390841 | LGG | Male-baised eQTL |
| rs2358606 | chr19:20790922:C:T | - | 0.0505453642702411 | 0.0422823998326507 | LGG | Male-baised eQTL |
| rs2358607 | chr19:20792997:G:T | - | 0.0505453642702411 | 0.0422823998326507 | LGG | Male-baised eQTL |
| rs8103964 | chr19:20924696:T:C | - | 0.0497662017146076 | 0.0451536439657813 | LGG | Male-baised eQTL |
| rs12984551 | chr19:20953597:C:A | - | 0.0497888703987397 | 0.0480509938864637 | LGG | Male-baised eQTL |
| rs148763045 | chr19:11771688:T:C | - | 0.0907654339443593 | 0.0269898481176598 | BLCA | Male-baised eQTL |
| rs451036 | chr19:11769002:T:C | - | 0.0902224501078191 | 0.0288030530097943 | BLCA | Male-baised eQTL |
| rs61318047 | chr19:11769659:C:G | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs56933482 | chr19:11769666:A:C | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs4352156 | chr19:11769864:C:T | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs60198456 | chr19:11769925:C:T | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs6511759 | chr19:11770342:T:C | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs6511760 | chr19:11770397:T:C | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs7257163 | chr19:11770531:A:G | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs10419444 | chr19:11770797:G:C | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs8111060 | chr19:11771258:C:G | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs8113205 | chr19:11771425:G:A | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs8100447 | chr19:11771477:A:G | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs59685848 | chr19:11771546:C:T | - | 0.0884451277807472 | 0.0330524368409757 | BLCA | Male-baised eQTL |
| rs4808410 | chr19:15922675:C:T | - | -0.0500537886619052 | 0.0381657760439592 | BLCA | Male-baised eQTL |
| rs8100091 | chr19:11770981:T:A | - | 0.0870592334226676 | 0.0397036091387066 | BLCA | Male-baised eQTL |
| rs4503923 | chr19:15920587:A:G | - | -0.0489668917509337 | 0.0434185145270718 | BLCA | Male-baised eQTL |
| rs12972171 | chr19:15915330:T:C | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs12971888 | chr19:15915394:A:G | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs12978382 | chr19:15915453:T:A | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs6512074 | chr19:15916084:G:A | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs6512075 | chr19:15916257:T:C | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs6512076 | chr19:15916355:G:A | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs12978826 | chr19:15916823:G:A | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs12981776 | chr19:15916937:A:G | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs8113140 | chr19:15919298:A:C | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs11667406 | chr19:15920242:T:C | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs12978309 | chr19:15920378:A:T | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs2365175 | chr19:15920632:C:T | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs2365173 | chr19:15920875:A:G | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs12460606 | chr19:15921574:A:G | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs11086013 | chr19:15921887:T:G | - | -0.0491290228068876 | 0.0440839286837766 | BLCA | Male-baised eQTL |
| rs157182 | chr19:12016961:T:C | - | 0.0973122422765628 | 0.00800432430241282 | LUAD | Male-baised eQTL |
| rs117480200 | chr19:12130160:A:C | - | 0.108688143295515 | 0.00981770184978088 | LUAD | Male-baised eQTL |
| rs7254503 | chr19:8700228:G:A | - | 0.0637224129136363 | 0.0105921749030053 | LUAD | Male-baised eQTL |
| rs76403598 | chr19:12055367:A:G | - | 0.12508974859673 | 0.012913332891508 | LUAD | Male-baised eQTL |
| rs113033627 | chr19:12055554:T:C | - | 0.12508974859673 | 0.012913332891508 | LUAD | Male-baised eQTL |
| rs112081361 | chr19:12055750:C:T | - | 0.124963868304809 | 0.0131414888565405 | LUAD | Male-baised eQTL |
| rs7259226 | chr19:15154921:G:A | - | 0.0672276054118375 | 0.0136948838213001 | LUAD | Male-baised eQTL |
| rs78398345 | chr19:12043633:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs111259072 | chr19:12045754:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs112152876 | chr19:12045864:C:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs10417006 | chr19:12046438:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs7255420 | chr19:12047024:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs8106275 | chr19:12049448:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs7257355 | chr19:12050965:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs10421718 | chr19:12051035:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs7246419 | chr19:12051897:G:A | - | 0.127106385413767 | 0.014123353436587 | LUAD | Male-baised eQTL |
| rs768170 | chr19:15157708:A:G | - | 0.067067660051825 | 0.015396865117677 | LUAD | Male-baised eQTL |
| rs73000469 | chr19:12114509:A:C | - | 0.103625260790845 | 0.0161210347771768 | LUAD | Male-baised eQTL |
| rs1088069 | chr19:12030411:A:G | - | 0.0917482280660721 | 0.0164530979705831 | LUAD | Male-baised eQTL |
| rs1091350 | chr19:12030712:A:G | - | 0.0917482280660721 | 0.0164530979705831 | LUAD | Male-baised eQTL |
| rs56101707 | chr19:12154736:A:G | - | 0.103503051606578 | 0.0166740623736193 | LUAD | Male-baised eQTL |
| rs4809026 | chr19:15159248:G:C | - | 0.0667372612898069 | 0.0166993398482725 | LUAD | Male-baised eQTL |
| rs4646531 | chr19:15626093:T:C | - | 0.0608198123677453 | 0.0212866747630549 | LUAD | Male-baised eQTL |
| rs10405202 | chr19:15624799:T:C | - | 0.0607572071863881 | 0.0214090934314212 | LUAD | Male-baised eQTL |
| rs74428614 | chr19:10386684:G:A | - | 0.0711194140856255 | 0.0216440802934756 | LUAD | Male-baised eQTL |
| rs7259156 | chr19:10387790:G:A | - | 0.0711194140856255 | 0.0216440802934756 | LUAD | Male-baised eQTL |
| rs12720215 | chr19:10380706:G:C | - | 0.079429034497504 | 0.0219912880751957 | LUAD | Male-baised eQTL |
| rs28669833 | chr19:15619796:C:T | - | 0.0583055835354269 | 0.033204823627477 | LUAD | Male-baised eQTL |
| rs56758671 | chr19:15621264:G:C | - | 0.0583055835354269 | 0.033204823627477 | LUAD | Male-baised eQTL |
| rs58563744 | chr19:15621470:G:A | - | 0.0583055835354269 | 0.033204823627477 | LUAD | Male-baised eQTL |
| rs28434016 | chr19:15621530:A:G | - | 0.0583055835354269 | 0.033204823627477 | LUAD | Male-baised eQTL |
| rs12985021 | chr19:15148213:G:T | - | 0.0564447438137584 | 0.0357636908072825 | LUAD | Male-baised eQTL |
| rs12720218 | chr19:10380212:G:A | - | 0.0741427172146513 | 0.0390195305764561 | LUAD | Male-baised eQTL |
| rs4646524 | chr19:15616681:G:A | - | 0.0573477161608995 | 0.0410744880710043 | LUAD | Male-baised eQTL |
| rs55818144 | chr19:15627813:C:T | - | 0.0562583255655278 | 0.0438405273740418 | LUAD | Male-baised eQTL |
| rs60921772 | chr19:15627836:G:A | - | 0.0562583255655278 | 0.0438405273740418 | LUAD | Male-baised eQTL |
| rs2283606 | chr19:15629544:C:T | - | 0.0562583255655278 | 0.0438405273740418 | LUAD | Male-baised eQTL |
| rs13345601 | chr19:15631842:T:G | - | 0.0562583255655278 | 0.0438405273740418 | LUAD | Male-baised eQTL |
| rs13347027 | chr19:15631843:C:G | - | 0.0562583255655278 | 0.0438405273740418 | LUAD | Male-baised eQTL |
| rs10422156 | chr19:11327346:A:G | - | 0.0633890987122282 | 0.0472978165676293 | LUAD | Male-baised eQTL |
| rs17620592 | chr19:27923726:C:G | - | -0.0520228774621655 | 0.00786393684245657 | COAD | Male-baised eQTL |
| rs1821290 | chr19:23898768:C:T | - | -0.0652192231053823 | 0.0291288611842707 | COAD | Male-baised eQTL |
| rs6511675 | chr19:23942485:G:A | - | -0.0719075209259137 | 0.0347863354951595 | COAD | Male-baised eQTL |
| rs16980187 | chr19:15004945:C:T | - | 0.0405546503260303 | 0.0434881543786915 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000130511 |
| CpG Site: cg00751072 | |
| Position to Gene: promoter | |
| Male Effect: -0.129070578235605 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg00751072 | chr19:18418311 | promoter | -0.129070578235605 | 2.04914478487326e-05 | -0.3541271237639352 | 5.4581659801547615e-08 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_303809 | chr19:18431352:18431418 | In-frame | rs187957 | chr19:18517706:A:T | Distant downstream | 0.0521338476358156 | 0.0401408444527529 | LUAD | Male-baised sQTL |
| exon_skip_303809 | chr19:18431352:18431418 | In-frame | rs7246328 | chr19:18508247:T:C | Distant downstream | 0.0502678075834758 | 0.0476294621541159 | LUAD | Male-baised sQTL |
| exon_skip_303809 | chr19:18431352:18431418 | In-frame | rs1019445 | chr19:18342314:T:C | Distant upstream | 0.0564294280374671 | 0.0332533449521092 | HNSC | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of SSBP4 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
