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Center for Computational Systems Medicine
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Gene summary

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Gene structure and Gene expression level

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Sex-biased somatic mutation

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DNA methylation with beta values in gene

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Exon skipping events with PSI in TCGA

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RNA A-to-I editing events in TCGA

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Sex-biased TF-Gene network of gene

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Sex-biased RBP-ES network of gene

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Sex-biased CeRNA regulation of gene

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Sex-biased eQTL regulation of gene

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Sex-biased eQTM regulation of gene

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Sex-biased sQTL regulation of gene

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Sex-biased sQTM regulation of gene

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Related disease information of gene

Gene: ENSG00000126947

Summary for ARMCX1

check button Gene summary

Gene informationEnsembl ID

ENSG00000126947

Gene symbol

ARMCX1

Gene namearmadillo repeat containing X-linked 1
HGNC

18073

Entrez ID

51309

Gene typeprotein_coding
SynonymsARMCX1|ALEX1|GASP7
UniProtAcc

Q9P291


check buttonDrugs associated with this gene(DrugBank).
Gene IDGene SymbolDrug IDDrug NameDrug Type

check buttonCancer therapeutic drugs associated with this gene(NCI).
Gene IDGene NameDrug IDDrug NameDrug TypeCancer

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Structure and expression level for ARMCX1

check buttonAS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.
UCSC result

check buttonLandscape of gene expressions across multiple cancer types.
gene expression analysis

check buttonDifferentially expressed gene analysis between tumor male and tumor female samples.
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type

check buttonDifferentially expressed gene analysis between tumor male and normal male samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
ARMCX16.25e+02-1.21e+001.73e-01-6.98e+002.94e-128.66e-12LUSC
ARMCX13.91e+021.21e+004.84e-012.50e+001.23e-022.96e-02CHOL

check buttonDifferentially expressed gene analysis between tumor female and normal female samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
ARMCX11.93e+02-2.73e+003.82e-01-7.14e+009.22e-134.21e-11READ

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Sex-biased somatic mutation for ARMCX1

∗For more information on exon skipping events please check the ExonskipDB database.
Gene IDCancer TypeHugo SymbolMaleFemalepvalorci.upci.lowadjPval

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DNA methylation with beta values for ARMCX1

check buttonLandscape of DNA methylation across multiple cancer types.
methylation heatmap

check buttonDifferentially expressed CpG sites between male tumor and female tumor patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
BRCAcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.29e-011.76e-025.16e+002.43e-071.16e-054.11e-01
BRCAcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.56e-018.33e-01-4.37e+001.22e-052.73e-04-1.77e-01
BRCAcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.00e-015.75e-025.01e+005.41e-071.72e-051.42e-01
BRCAcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.55e-015.63e-023.88e+001.06e-041.77e-031.99e-01
BRCAcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.54e-015.43e-025.16e+002.46e-071.16e-053.99e-01
BRCAcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.09e-017.66e-024.00e+006.34e-051.15e-033.33e-01
BRCAcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.25e-011.47e-014.91e+009.17e-072.65e-052.78e-01
KIRCcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter1.71e-016.90e-028.39e+004.92e-175.61e-161.02e-01
LGGcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.22e-012.04e-021.97e+015.28e-861.96e-844.02e-01
LGGcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.93e-018.80e-01-1.82e+011.03e-731.77e-72-1.86e-01
LGGcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter1.63e-015.00e-021.82e+015.71e-749.92e-731.13e-01
LGGcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.14e-014.93e-021.87e+014.00e-787.95e-771.65e-01
LGGcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.75e-014.63e-021.98e+016.57e-873.36e-854.29e-01
LGGcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.87e-019.56e-021.83e+011.26e-742.23e-732.92e-01
LGGcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.33e-017.61e-021.93e+011.32e-823.24e-813.57e-01
LGGcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.86e-011.18e-011.87e+012.12e-784.26e-772.68e-01
LUSCcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.32e-011.48e-011.02e+011.94e-242.23e-232.84e-01
LUSCcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.30e-011.09e-011.08e+012.08e-272.54e-261.21e-01
LUSCcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.52e-011.38e-019.46e+003.05e-213.26e-201.15e-01
LUSCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.48e-011.70e-011.04e+011.64e-251.94e-242.79e-01
LUSCcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.84e-012.02e-019.32e+001.18e-201.25e-191.81e-01
LUSCcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.43e-011.93e-011.01e+015.53e-246.28e-232.50e-01
SKCMcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.33e-013.76e-021.73e+016.09e-671.36e-652.95e-01
SKCMcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.64e-018.52e-01-1.43e+011.94e-462.65e-45-1.88e-01
SKCMcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter1.78e-016.05e-021.61e+012.46e-584.21e-571.17e-01
SKCMcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter1.76e-016.26e-021.59e+017.24e-571.21e-551.13e-01
SKCMcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.48e-016.31e-021.75e+013.42e-688.13e-672.85e-01
SKCMcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body2.97e-011.13e-011.50e+011.15e-501.69e-491.84e-01
SKCMcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.46e-019.94e-021.61e+015.28e-589.00e-572.46e-01
SKCMcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.46e-012.10e-011.19e+017.57e-337.77e-321.37e-01
STADcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.25e-013.88e-014.08e+004.57e-052.37e-041.38e-01
STADcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.45e-011.43e-019.08e+001.08e-191.24e-181.02e-01
STADcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.57e-014.13e-014.25e+002.13e-051.14e-041.44e-01
STADcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body5.54e-014.21e-013.85e+001.18e-045.83e-041.32e-01
KIRPcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter2.12e-017.96e-023.57e+003.61e-042.23e-031.32e-01
SARCcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.41e-012.73e-021.36e+014.04e-423.38e-403.13e-01
SARCcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.09e-018.68e-01-1.04e+011.50e-252.87e-24-1.58e-01
SARCcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter1.70e-016.62e-028.63e+006.12e-187.75e-171.04e-01
SARCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.90e-016.06e-021.35e+012.83e-411.85e-393.30e-01
SARCcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.56e-011.11e-011.01e+015.03e-248.79e-232.45e-01
SARCcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.74e-018.73e-021.21e+017.90e-342.53e-322.86e-01
SARCcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.14e-011.53e-011.05e+018.63e-261.69e-241.61e-01
PCPGcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body2.62e-011.96e-021.16e+014.36e-311.93e-292.43e-01
PCPGcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.24e-017.71e-01-6.34e+002.32e-101.30e-09-1.47e-01
PCPGcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.98e-014.49e-021.16e+013.96e-311.92e-293.53e-01
PCPGcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.02e-019.93e-029.29e+001.53e-201.51e-192.03e-01
PCPGcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.10e-017.84e-021.16e+016.06e-312.16e-293.31e-01
PCPGcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.04e-011.05e-011.09e+019.17e-281.39e-261.99e-01
PAADcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.47e-019.61e-029.70e+002.94e-224.88e-213.51e-01
PAADcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter2.15e-011.09e-015.82e+005.71e-094.36e-081.07e-01
PAADcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.49e-016.93e-021.05e+019.70e-261.91e-241.80e-01
PAADcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.90e-019.83e-029.40e+005.39e-218.41e-201.92e-01
PAADcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.00e-011.18e-011.02e+011.77e-243.27e-233.82e-01
PAADcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body4.23e-011.68e-019.20e+003.50e-205.16e-192.55e-01
PAADcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.88e-011.54e-019.21e+003.14e-204.63e-193.34e-01
PAADcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.39e-012.95e-016.26e+003.91e-103.20e-091.44e-01
READcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.79e-012.56e-014.79e+001.65e-069.51e-063.23e-01
READcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter3.65e-011.80e-014.10e+004.14e-052.06e-041.85e-01
READcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.01e-011.00e-016.19e+006.19e-104.89e-091.01e-01
READcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter3.59e-011.96e-014.55e+005.37e-062.95e-051.63e-01
READcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body6.00e-012.81e-014.87e+001.11e-066.52e-063.18e-01
READcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body5.16e-013.02e-014.10e+004.14e-052.06e-042.14e-01
READcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body6.41e-014.24e-013.15e+001.63e-036.13e-032.17e-01
GBMcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.77e-011.70e-026.75e+001.48e-112.64e-104.60e-01
GBMcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter1.87e-017.85e-022.35e+001.89e-023.46e-021.08e-01
GBMcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.41e-018.38e-01-5.54e+003.00e-082.42e-07-1.97e-01
GBMcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter1.61e-014.64e-026.61e+003.81e-115.19e-101.15e-01
GBMcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.39e-014.83e-026.38e+001.83e-102.10e-091.90e-01
GBMcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.82e-014.14e-026.75e+001.48e-112.64e-104.40e-01
GBMcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.66e-011.00e-015.51e+003.51e-082.82e-072.66e-01
GBMcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.51e-016.63e-026.75e+001.48e-112.64e-103.85e-01
GBMcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.21e-011.45e-016.54e+006.08e-117.90e-102.76e-01
GBMcg00040923chrX:101551897CGI:chrX:101552810-101553065promoter,gene body6.95e-018.00e-01-3.35e+008.16e-043.36e-03-1.05e-01
ESCAcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.42e-013.13e-012.98e+002.91e-031.11e-022.28e-01
ESCAcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.88e-013.45e-013.26e+001.13e-035.02e-032.43e-01
ESCAcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body5.07e-013.52e-012.57e+001.00e-022.67e-021.55e-01
ESCAcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body6.21e-013.72e-013.61e+003.11e-041.55e-032.50e-01
LAMLcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.02e-013.65e-021.00e+011.52e-233.58e-224.66e-01
LAMLcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter2.65e-018.77e-024.45e+008.67e-063.08e-051.77e-01
LAMLcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.45e-018.68e-01-8.34e+007.56e-174.99e-16-1.23e-01
LAMLcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.78e-014.35e-029.90e+004.00e-236.23e-222.34e-01
LAMLcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.54e-015.20e-029.86e+006.35e-238.87e-222.02e-01
LAMLcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.17e-016.19e-029.99e+001.71e-233.74e-224.55e-01
LAMLcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body4.76e-011.19e-019.63e+005.71e-225.81e-213.56e-01
LAMLcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.71e-018.23e-021.01e+015.74e-242.72e-223.88e-01
LAMLcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body5.11e-013.16e-017.36e+001.88e-131.02e-121.94e-01
THYMcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.16e-013.44e-028.96e+003.15e-193.04e-183.81e-01
THYMcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.14e-018.46e-01-7.94e+002.08e-151.33e-14-1.32e-01
THYMcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter2.38e-015.02e-028.87e+007.13e-196.62e-181.88e-01
THYMcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.20e-014.41e-029.10e+008.90e-209.74e-191.75e-01
THYMcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.88e-016.04e-029.11e+008.07e-208.94e-194.27e-01
THYMcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.85e-019.64e-027.92e+002.47e-151.57e-142.89e-01
THYMcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.77e-019.45e-028.76e+001.93e-181.68e-173.82e-01
THYMcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.44e-012.51e-018.40e+004.49e-173.44e-161.93e-01
MESOcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.74e-012.64e-026.04e+001.57e-092.60e-083.48e-01
MESOcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.96e-018.47e-01-4.92e+008.57e-076.93e-06-1.51e-01
MESOcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter1.80e-015.37e-025.10e+003.32e-072.84e-061.26e-01
MESOcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.96e-015.79e-026.06e+001.36e-092.54e-083.38e-01
MESOcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body2.93e-011.14e-014.22e+002.48e-051.67e-041.79e-01
MESOcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.62e-011.01e-015.93e+002.94e-094.03e-082.62e-01
MESOcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.39e-011.56e-015.18e+002.17e-071.91e-061.83e-01
UVMcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body2.81e-011.76e-027.64e+002.21e-149.97e-132.63e-01
UVMcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.68e-019.01e-01-6.34e+002.33e-101.78e-09-1.33e-01
UVMcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter1.49e-014.23e-025.73e+001.02e-086.18e-081.07e-01
UVMcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.72e-014.20e-027.63e+002.39e-149.97e-133.30e-01
UVMcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.44e-018.68e-026.34e+002.33e-101.78e-092.57e-01
UVMcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.35e-017.90e-026.78e+001.17e-111.05e-102.56e-01
UVMcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body2.66e-011.07e-016.20e+005.57e-104.10e-091.59e-01
ACCcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.86e-011.93e-027.46e+008.66e-142.68e-123.67e-01
ACCcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.35e-019.68e-026.92e+004.59e-126.86e-112.38e-01
ACCcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body3.23e-018.64e-026.91e+004.93e-127.33e-112.37e-01
ACCcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.73e-016.75e-027.27e+003.62e-137.24e-123.05e-01
ACCcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.06e-018.94e-01-7.06e+001.69e-122.79e-11-1.88e-01
ACCcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter1.85e-014.14e-026.84e+008.06e-121.16e-101.43e-01
ACCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.28e-014.41e-027.47e+008.02e-142.68e-123.84e-01
KICHcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body2.57e-012.46e-026.55e+005.83e-111.88e-092.33e-01
KICHcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body2.89e-014.67e-026.56e+005.33e-111.88e-092.42e-01
KICHcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body2.35e-018.38e-026.12e+009.39e-101.35e-081.51e-01
KICHcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body2.50e-017.57e-026.39e+001.69e-103.26e-091.74e-01
KICHcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body2.73e-011.42e-015.38e+007.32e-087.49e-071.31e-01
DLBCcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body6.83e-014.85e-012.67e+007.60e-031.87e-021.98e-01
DLBCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body7.18e-015.34e-012.21e+002.68e-024.02e-021.83e-01
CHOLcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body5.00e-011.39e-014.04e+005.27e-052.87e-043.61e-01
CHOLcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter6.40e-017.99e-01-3.50e+004.62e-041.99e-03-1.58e-01
CHOLcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter3.30e-011.55e-013.25e+001.17e-034.25e-031.76e-01
CHOLcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.88e-011.43e-013.82e+001.33e-046.65e-043.45e-01
CHOLcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body4.73e-012.01e-012.48e+001.30e-022.54e-022.72e-01
CHOLcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.30e-011.46e-013.88e+001.03e-045.28e-042.84e-01
CHOLcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.47e-012.68e-012.87e+004.17e-031.13e-021.80e-01

check buttonDifferentially expressed CpG sites between male tumor and male normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
LUADcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.28e-018.49e-01-3.32e+009.05e-041.78e-03-1.21e-01
LUADcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.23e-011.81e-014.40e+001.07e-054.45e-051.41e-01
HNSCcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body1.53e-012.27e-023.67e+002.46e-045.52e-041.30e-01
HNSCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body1.83e-014.92e-023.18e+001.47e-032.51e-031.34e-01
HNSCcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body2.14e-019.34e-022.49e+001.28e-021.58e-021.20e-01
HNSCcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body2.42e-018.30e-022.96e+003.05e-034.68e-031.59e-01
HNSCcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.44e-012.11e-015.02e+005.16e-073.43e-062.33e-01
HNSCcg00040923chrX:101551897CGI:chrX:101552810-101553065promoter,gene body7.76e-016.09e-015.16e+002.43e-071.90e-061.68e-01
LUSCcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body1.48e-011.77e-023.49e+004.74e-041.60e-031.30e-01
LUSCcg20593767chrX:101549051CGI:chrX:101552810-101553065promoter7.23e-018.72e-01-3.65e+002.62e-041.13e-03-1.49e-01
LUSCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body1.70e-014.43e-023.03e+002.42e-034.78e-031.25e-01
LUSCcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body2.02e-018.52e-022.69e+007.16e-031.07e-021.17e-01
LUSCcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body1.93e-017.09e-022.69e+007.05e-031.06e-021.22e-01
LUSCcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body3.59e-011.96e-013.24e+001.19e-032.92e-031.63e-01
LUSCcg00040923chrX:101551897CGI:chrX:101552810-101553065promoter,gene body7.51e-015.85e-013.59e+003.26e-041.28e-031.66e-01
COADcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body4.55e-015.86e-022.94e+003.29e-035.91e-033.96e-01
COADcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter3.07e-017.51e-022.67e+007.51e-031.14e-022.32e-01
COADcg10513418chrX:101550314CGI:chrX:101552810-101553065promoter1.68e-016.12e-022.10e+003.58e-023.87e-021.07e-01
COADcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter3.67e-015.64e-022.79e+005.30e-038.66e-033.11e-01
COADcg18731813chrX:101550700CGI:chrX:101552810-101553065promoter,gene body5.06e-011.18e-013.39e+007.09e-041.70e-033.88e-01
COADcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body6.02e-013.58e-014.55e+005.47e-063.78e-052.43e-01
BLCAcg09813276chrX:101550538CGI:chrX:101552810-101553065UTR,promoter,exon,gene body2.37e-015.42e-022.11e+003.48e-023.78e-021.83e-01
BLCAcg19687016chrX:101550509CGI:chrX:101552810-101553065promoter1.93e-016.61e-022.96e+003.08e-035.53e-031.27e-01
BLCAcg23116589chrX:101550520CGI:chrX:101552810-101553065promoter2.19e-016.56e-022.48e+001.30e-021.74e-021.53e-01
BLCAcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body2.59e-016.62e-022.02e+004.29e-024.44e-021.93e-01
BLCAcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.92e-011.14e-012.41e+001.60e-022.05e-022.77e-01
BLCAcg12947498chrX:101551414CGI:chrX:101552810-101553065promoter,gene body4.96e-012.27e-013.54e+004.04e-041.13e-032.68e-01
BLCAcg00040923chrX:101551897CGI:chrX:101552810-101553065promoter,gene body7.62e-015.37e-014.27e+001.91e-051.36e-042.25e-01
CHOLcg00040923chrX:101551897CGI:chrX:101552810-101553065promoter,gene body8.42e-016.46e-013.54e+004.02e-048.32e-031.96e-01

check buttonDifferentially expressed CpG sites between female tumor and female normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
BRCAcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body4.09e-015.26e-01-8.98e+002.82e-191.43e-18-1.17e-01
LIHCcg25576048chrX:101550533CGI:chrX:101552810-101553065UTR,promoter,exon,gene body3.99e-015.30e-01-3.23e+001.23e-032.66e-03-1.31e-01
LIHCcg20291091chrX:101551051CGI:chrX:101552810-101553065promoter,gene body3.40e-015.01e-01-3.72e+001.99e-046.49e-04-1.60e-01

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Exon skipping events with PSI in TCGA for ARMCX1

∗Please access ExonSkipDB for exon skipping annotation.
check buttonLandscape of exon skipping events across multiple cancer types.
AS event heatmap

check buttonDifferentially expressed exon skipping events between male tumor and female tumor patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between male tumor and male normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between female tumor and female normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

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RNA A-to-I editing events in TCGA for ARMCX1

∗Please access CAeditome for RNA editing annotation.
check buttonDifferentially expressed RNA editing events between male tumor and female tumor patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonDifferentially expressed RNA editing events between male tumor and male normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonDifferentially expressed RNA editing events between female tumor and female normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonProtein coding RNA editing(s).
Editing PositionVariant TypeGene SymbolTranscript IDNTchangeAAchange

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Sex-biased TF-Gene network for ARMCX1

check buttonTFs related to ARMCX1.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
TF Gene
Cancer TypeTFTarget GeneMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType
DLBCZNF418ARMCX14.67e+001.14e-025.53e+009.87e-01Female-biased
ESCAKLF16ARMCX14.00e+009.87e-012.80e+006.12e-04Male-biased
ESCARBAKARMCX14.14e+009.89e-013.14e+001.90e-03Male-biased
ESCATFAP4ARMCX14.16e+009.86e-013.31e+004.60e-03Male-biased
ESCAUSF1ARMCX14.47e+009.83e-013.76e+001.10e-02Male-biased
ESCAZNF16ARMCX14.17e+009.88e-013.25e+003.10e-03Male-biased
ESCAZNF180ARMCX13.80e+009.82e-012.64e+007.83e-04Male-biased
ESCAZNF267ARMCX14.28e+009.92e-013.01e+004.38e-04Male-biased
ESCAZNF311ARMCX14.48e+009.94e-013.18e+003.72e-04Male-biased
ESCAZNF331ARMCX14.15e+009.89e-013.04e+001.06e-03Male-biased
ESCAZNF398ARMCX14.04e+009.83e-013.23e+005.70e-03Male-biased
ESCAZNF415ARMCX14.35e+009.91e-013.38e+002.44e-03Male-biased
ESCAZNF418ARMCX13.02e+008.25e-044.35e+009.93e-01Female-biased
ESCAZNF44ARMCX14.38e+009.93e-013.21e+007.58e-04Male-biased
ESCAZNF454ARMCX14.19e+009.90e-013.10e+001.17e-03Male-biased
ESCAZNF529ARMCX14.10e+009.89e-012.85e+004.63e-04Male-biased
ESCAZNF530ARMCX14.25e+009.92e-012.99e+004.57e-04Male-biased
ESCAZNF566ARMCX14.47e+009.94e-013.22e+004.81e-04Male-biased
ESCAZNF662ARMCX14.20e+009.90e-013.05e+008.61e-04Male-biased
ESCAZNF776ARMCX14.27e+009.90e-013.29e+002.19e-03Male-biased
ESCAZNF93ARMCX14.06e+009.88e-012.90e+007.85e-04Male-biased
LAMLBARHL2ARMCX15.83e+009.87e-014.95e+001.15e-02Male-biased
LAMLMECOMARMCX14.96e+009.88e-013.99e+008.07e-03Male-biased
LAMLMIXL1ARMCX15.76e+009.85e-014.93e+001.37e-02Male-biased
LAMLPROP1ARMCX15.76e+009.88e-014.86e+001.11e-02Male-biased
LAMLZNF232ARMCX15.50e+009.90e-014.54e+008.52e-03Male-biased
MESOZNF418ARMCX14.36e+001.30e-025.56e+009.85e-01Female-biased
PAADZNF418ARMCX14.33e+009.91e-012.87e+003.86e-04Male-biased
READBARHL2ARMCX15.22e+001.33e-025.98e+009.86e-01Female-biased
READLYL1ARMCX14.19e+009.85e-012.90e+001.58e-03Male-biased
READMIXL1ARMCX15.30e+001.35e-026.06e+009.86e-01Female-biased
READPROP1ARMCX15.42e+001.39e-026.17e+009.85e-01Female-biased
READRBAKARMCX14.42e+009.89e-013.12e+001.51e-03Male-biased
READTFAP4ARMCX14.52e+009.91e-013.22e+001.58e-03Male-biased
READZNF16ARMCX14.49e+009.90e-013.23e+001.83e-03Male-biased
READZNF232ARMCX15.01e+001.50e-025.74e+009.84e-01Female-biased
READZNF267ARMCX14.14e+009.81e-013.08e+003.72e-03Male-biased
READZNF311ARMCX14.29e+009.85e-013.20e+003.38e-03Male-biased
READZNF331ARMCX14.62e+009.93e-012.98e+004.49e-04Male-biased
READZNF398ARMCX14.26e+009.84e-013.21e+004.00e-03Male-biased
READZNF415ARMCX14.63e+009.93e-013.13e+007.24e-04Male-biased
READZNF418ARMCX12.84e+001.59e-044.88e+009.96e-01Female-biased
READZNF44ARMCX14.33e+009.87e-013.18e+002.58e-03Male-biased
READZNF454ARMCX14.54e+009.92e-012.91e+004.50e-04Male-biased
READZNF530ARMCX14.45e+009.91e-012.87e+005.58e-04Male-biased
READZNF566ARMCX14.45e+009.88e-013.37e+003.46e-03Male-biased
READZNF662ARMCX14.43e+009.90e-012.91e+006.82e-04Male-biased
READZNF776ARMCX14.41e+009.88e-013.23e+002.41e-03Male-biased
READZNF791ARMCX14.65e+009.82e-013.87e+001.14e-02Male-biased
READZNF93ARMCX14.17e+009.83e-013.08e+003.20e-03Male-biased
SARCZNF418ARMCX13.96e+009.44e-034.62e+009.85e-01Female-biased
SKCMZNF418ARMCX16.08e+001.94e-026.85e+009.80e-01Female-biased

check buttonARMCX1 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for ARMCX1

check buttonRBPs related to ES in ARMCX1.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
Cancer TypeRBPTarget ESMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType

check buttonARMCX1 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

check buttonSex-biased CeRNA regulation of gene.
Gene IDceRNA(lncRNA-miRNA-mRNA)GroupCancer Type

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Sex-biased eQTL regulation of gene

check buttonSex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
eQTLDescription

check buttonMale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type

check buttonFemale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type

check buttonOpposite sex-biased eQTL regulation.
SNP IDSNP InfoPosition to GeneMale EffectMale FDRFemale EffectFemale FDRSex-biased Gene in CancerCancer Type

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Sex-biased eQTM regulation of gene

check buttonSex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).
eQTMDescription
eQTM boxplot analysisGene ID: ENSG00000126947
CpG Site: cg18731813
Position to Gene: gene,promoter
Male Effect: -0.0616182538033158
Female Effect: -
eQTM boxplot analysisGene ID: ENSG00000126947
CpG Site: cg12947498
Position to Gene: gene,promoter
Male Effect: -0.0821543509855145
Female Effect: -

check buttonMale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type
cg18731813chrX:101550700gene,promoter-0.06161825380331586.28418243899056e-05-0.35353808055834791.4122256038534481e-07STAD
cg12947498chrX:101551414gene,promoter-0.08215435098551451.21570065434517e-10-0.40065035637917613.455050308516395e-13BLCA

check buttonFemale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type

check buttonOpposite sex-biased eQTM regulation.
CpG SiteCpG PostionCpG IslandPosition to GeneMale EffectMale FDRFemale EffectFemale FDRMale CorMale P-valueFemale CorFemale P-valueSex-biased Coding GeneCancer Type

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Sex-biased sQTL regulation of gene

check buttonSex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTLDescription

check buttonMale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonFemale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonOpposite sex-biased sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESMale EffectMale FDRFemale EffectFemale FDRCancer Type

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Sex-biased sQTM regulation of gene

check buttonSex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTMDescription

check buttonMale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonFemale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonOpposite sex-biased sQTM regulation.
EX IDEX InfoSkipped ExonCPG SiteCPG PositionCPG IslandPosition to EX EventsMale EffectMale FDRFemale EffectFemale FDRMale CorrelationMale P-valueFemale CorrelationFemale P-valueORF_annoCancer Type

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Related disease information of ARMCX1

check buttonDiseases associated with this gene (DisGeNET).
Gene IDGene SymbolDisease IDDisease NameNumber of PMIDSource
ENSG00000126947ARMCX1C0023893Liver Cirrhosis, Experimental1CTD_human