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Gene: ENSG00000123094 |
Summary for RASSF8 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000123094 | Gene symbol | RASSF8 |
| Gene name | Ras association domain family member 8 | |
| HGNC | 13232 | |
| Entrez ID | 11228 | |
| Gene type | protein_coding | |
| Synonyms | RASSF8|HoJ-1 | |
| UniProtAcc | Q8NHQ8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for RASSF8 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| RASSF8 | 1.54e+03 | -1.18e+00 | 1.50e-01 | -7.87e+00 | 3.48e-15 | 4.15e-14 | KIRP |
| RASSF8 | 2.82e+02 | -1.15e+00 | 3.19e-01 | -3.62e+00 | 2.97e-04 | 7.45e-04 | COAD |
| RASSF8 | 1.15e+03 | 1.34e+00 | 3.68e-01 | 3.65e+00 | 2.60e-04 | 1.03e-03 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| RASSF8 | 2.47e+03 | -1.01e+00 | 2.53e-01 | -3.98e+00 | 6.98e-05 | 1.91e-04 | KICH |
| RASSF8 | 2.83e+02 | -2.32e+00 | 5.11e-01 | -4.54e+00 | 5.60e-06 | 3.94e-05 | READ |
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Sex-biased somatic mutation for RASSF8 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for RASSF8 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| STAD | cg04563419 | chr12:25959521 | CGI:chr12:25958258-25959390 | promoter,gene body | 1.20e-01 | 2.53e-01 | 5.78e+00 | 7.57e-09 | 5.12e-08 | -1.33e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg03211239 | chr12:25957585 | CGI:chr12:25958258-25959390 | promoter | 7.95e-01 | 9.16e-01 | -3.41e+00 | 6.60e-04 | 1.98e-03 | -1.20e-01 |
| LUSC | cg21373145 | chr12:25957733 | CGI:chr12:25958258-25959390 | promoter | 7.99e-01 | 9.14e-01 | -3.11e+00 | 1.85e-03 | 3.96e-03 | -1.14e-01 |
| LUSC | cg15282709 | chr12:25957767 | CGI:chr12:25958258-25959390 | promoter | 7.60e-01 | 8.78e-01 | -2.49e+00 | 1.27e-02 | 1.67e-02 | -1.18e-01 |
| COAD | cg03211239 | chr12:25957585 | CGI:chr12:25958258-25959390 | promoter | 6.57e-01 | 8.21e-01 | -2.49e+00 | 1.29e-02 | 1.76e-02 | -1.64e-01 |
| BLCA | cg03211239 | chr12:25957585 | CGI:chr12:25958258-25959390 | promoter | 7.85e-01 | 8.91e-01 | -2.80e+00 | 5.12e-03 | 8.29e-03 | -1.06e-01 |
| KIRP | cg21373145 | chr12:25957733 | CGI:chr12:25958258-25959390 | promoter | 5.37e-01 | 4.37e-01 | 2.23e+00 | 2.58e-02 | 2.86e-02 | 1.00e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg15282709 | chr12:25957767 | CGI:chr12:25958258-25959390 | promoter | 8.62e-01 | 7.48e-01 | 1.15e+01 | 8.26e-31 | 1.33e-29 | 1.14e-01 |
| KIRC | cg21373145 | chr12:25957733 | CGI:chr12:25958258-25959390 | promoter | 5.19e-01 | 4.19e-01 | 2.11e+00 | 3.51e-02 | 3.93e-02 | 1.00e-01 |
| KIRC | cg15282709 | chr12:25957767 | CGI:chr12:25958258-25959390 | promoter | 4.69e-01 | 3.58e-01 | 2.43e+00 | 1.53e-02 | 2.26e-02 | 1.12e-01 |
| KIRP | cg15282709 | chr12:25957767 | CGI:chr12:25958258-25959390 | promoter | 5.00e-01 | 3.72e-01 | 2.28e+00 | 2.26e-02 | 2.91e-02 | 1.28e-01 |
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Exon skipping events with PSI in TCGA for RASSF8 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for RASSF8 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for RASSF8 |
| TFs related to RASSF8. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | ALX1 | RASSF8 | 3.80e+00 | 8.22e-03 | 4.70e+00 | 9.86e-01 | Female-biased |
| BLCA | ALX3 | RASSF8 | 4.27e+00 | 1.47e-02 | 5.03e+00 | 9.82e-01 | Female-biased |
| BLCA | ALX4 | RASSF8 | 4.17e+00 | 1.18e-02 | 4.99e+00 | 9.85e-01 | Female-biased |
| BLCA | ARGFX | RASSF8 | 4.23e+00 | 1.51e-02 | 4.98e+00 | 9.81e-01 | Female-biased |
| BLCA | DRGX | RASSF8 | 4.00e+00 | 9.91e-03 | 4.86e+00 | 9.86e-01 | Female-biased |
| BLCA | DUX4 | RASSF8 | 3.74e+00 | 8.06e-03 | 4.65e+00 | 9.86e-01 | Female-biased |
| BLCA | EMX1 | RASSF8 | 3.69e+00 | 7.49e-03 | 4.62e+00 | 9.86e-01 | Female-biased |
| BLCA | EMX2 | RASSF8 | 3.55e+00 | 5.16e-03 | 4.57e+00 | 9.88e-01 | Female-biased |
| BLCA | FOXD3 | RASSF8 | 3.05e+00 | 1.92e-03 | 4.31e+00 | 9.88e-01 | Female-biased |
| BLCA | FOXJ2 | RASSF8 | 2.50e+00 | 9.29e-04 | 3.94e+00 | 9.81e-01 | Female-biased |
| BLCA | FOXJ3 | RASSF8 | 2.84e+00 | 2.66e-03 | 4.01e+00 | 9.81e-01 | Female-biased |
| BLCA | FOXL1 | RASSF8 | 2.36e+00 | 2.76e-04 | 4.13e+00 | 9.86e-01 | Female-biased |
| BLCA | FOXR2 | RASSF8 | 2.66e+00 | 4.10e-04 | 4.33e+00 | 9.90e-01 | Female-biased |
| BLCA | HESX1 | RASSF8 | 3.60e+00 | 4.93e-03 | 4.63e+00 | 9.89e-01 | Female-biased |
| BLCA | HOXB7 | RASSF8 | 3.41e+00 | 8.48e-03 | 4.30e+00 | 9.81e-01 | Female-biased |
| BLCA | ISX | RASSF8 | 3.88e+00 | 1.11e-02 | 4.70e+00 | 9.83e-01 | Female-biased |
| BLCA | LHX3 | RASSF8 | 3.32e+00 | 2.92e-03 | 4.48e+00 | 9.89e-01 | Female-biased |
| BLCA | LHX9 | RASSF8 | 3.80e+00 | 7.46e-03 | 4.73e+00 | 9.87e-01 | Female-biased |
| BLCA | NKX3-1 | RASSF8 | 3.33e+00 | 1.40e-03 | 4.68e+00 | 9.93e-01 | Female-biased |
| BLCA | NKX6-1 | RASSF8 | 2.79e+00 | 7.82e-04 | 4.29e+00 | 9.89e-01 | Female-biased |
| BLCA | PHOX2A | RASSF8 | 4.01e+00 | 9.49e-03 | 4.88e+00 | 9.86e-01 | Female-biased |
| BLCA | PHOX2B | RASSF8 | 3.73e+00 | 7.01e-03 | 4.67e+00 | 9.87e-01 | Female-biased |
| BLCA | POU3F2 | RASSF8 | 2.92e+00 | 8.15e-04 | 4.41e+00 | 9.91e-01 | Female-biased |
| BLCA | PROP1 | RASSF8 | 4.25e+00 | 1.41e-02 | 5.02e+00 | 9.83e-01 | Female-biased |
| BLCA | PRRX1 | RASSF8 | 3.98e+00 | 1.27e-02 | 4.78e+00 | 9.82e-01 | Female-biased |
| BLCA | SOX2 | RASSF8 | 3.61e+00 | 7.34e-03 | 4.54e+00 | 9.85e-01 | Female-biased |
| BLCA | SOX21 | RASSF8 | 3.56e+00 | 8.94e-03 | 4.43e+00 | 9.83e-01 | Female-biased |
| BLCA | SOX7 | RASSF8 | 3.11e+00 | 2.48e-03 | 4.31e+00 | 9.87e-01 | Female-biased |
| BLCA | SOX8 | RASSF8 | 3.16e+00 | 5.54e-03 | 4.14e+00 | 9.81e-01 | Female-biased |
| BLCA | SOX9 | RASSF8 | 3.26e+00 | 3.63e-03 | 4.36e+00 | 9.87e-01 | Female-biased |
| BLCA | TBP | RASSF8 | 3.22e+00 | 4.77e-03 | 4.24e+00 | 9.84e-01 | Female-biased |
| BLCA | UNCX | RASSF8 | 3.75e+00 | 7.89e-03 | 4.66e+00 | 9.86e-01 | Female-biased |
| BLCA | ZNF146 | RASSF8 | 2.84e+00 | 2.84e-03 | 3.99e+00 | 9.80e-01 | Female-biased |
| BLCA | ZNF25 | RASSF8 | 2.76e+00 | 8.53e-04 | 4.23e+00 | 9.88e-01 | Female-biased |
| BLCA | ZNF334 | RASSF8 | 2.74e+00 | 2.27e-04 | 4.57e+00 | 9.93e-01 | Female-biased |
| BLCA | ZNF35 | RASSF8 | 2.64e+00 | 6.90e-04 | 4.17e+00 | 9.87e-01 | Female-biased |
| BLCA | ZNF418 | RASSF8 | 1.95e+00 | 6.35e-06 | 4.64e+00 | 9.94e-01 | Female-biased |
| BLCA | ZNF584 | RASSF8 | 3.02e+00 | 2.37e-03 | 4.23e+00 | 9.86e-01 | Female-biased |
| BLCA | ZNF879 | RASSF8 | 1.83e+00 | 3.85e-05 | 4.09e+00 | 9.86e-01 | Female-biased |
| DLBC | ALX1 | RASSF8 | 2.99e+00 | 1.75e-03 | 4.37e+00 | 9.90e-01 | Female-biased |
| DLBC | ALX3 | RASSF8 | 3.58e+00 | 2.78e-03 | 4.84e+00 | 9.93e-01 | Female-biased |
| DLBC | ALX4 | RASSF8 | 3.52e+00 | 2.67e-03 | 4.78e+00 | 9.93e-01 | Female-biased |
| DLBC | ARGFX | RASSF8 | 3.48e+00 | 2.21e-03 | 4.80e+00 | 9.94e-01 | Female-biased |
| DLBC | DRGX | RASSF8 | 3.34e+00 | 2.52e-03 | 4.62e+00 | 9.92e-01 | Female-biased |
| DLBC | DUX4 | RASSF8 | 3.51e+00 | 1.01e-02 | 4.40e+00 | 9.82e-01 | Female-biased |
| DLBC | DUXA | RASSF8 | 3.26e+00 | 7.29e-03 | 4.23e+00 | 9.82e-01 | Female-biased |
| DLBC | EMX1 | RASSF8 | 3.33e+00 | 3.08e-03 | 4.55e+00 | 9.91e-01 | Female-biased |
| DLBC | EMX2 | RASSF8 | 3.24e+00 | 3.54e-03 | 4.41e+00 | 9.89e-01 | Female-biased |
| DLBC | FOXD3 | RASSF8 | 2.58e+00 | 1.50e-03 | 4.00e+00 | 9.84e-01 | Female-biased |
| DLBC | FOXO1 | RASSF8 | 3.07e+00 | 2.11e-03 | 4.40e+00 | 9.90e-01 | Female-biased |
| DLBC | FOXO3 | RASSF8 | 3.34e+00 | 3.31e-03 | 4.54e+00 | 9.90e-01 | Female-biased |
| DLBC | FOXO4 | RASSF8 | 3.42e+00 | 3.90e-03 | 4.58e+00 | 9.90e-01 | Female-biased |
| DLBC | FOXO6 | RASSF8 | 3.19e+00 | 3.33e-03 | 4.39e+00 | 9.89e-01 | Female-biased |
| DLBC | FOXR2 | RASSF8 | 2.70e+00 | 1.75e-03 | 4.07e+00 | 9.85e-01 | Female-biased |
| DLBC | HESX1 | RASSF8 | 3.14e+00 | 2.65e-03 | 4.40e+00 | 9.90e-01 | Female-biased |
| DLBC | HOXB7 | RASSF8 | 2.82e+00 | 2.64e-03 | 4.07e+00 | 9.84e-01 | Female-biased |
| DLBC | IRF7 | RASSF8 | 3.45e+00 | 1.06e-02 | 4.33e+00 | 9.80e-01 | Female-biased |
| DLBC | ISX | RASSF8 | 3.17e+00 | 1.80e-03 | 4.54e+00 | 9.92e-01 | Female-biased |
| DLBC | LHX3 | RASSF8 | 2.98e+00 | 2.33e-03 | 4.27e+00 | 9.88e-01 | Female-biased |
| DLBC | LHX9 | RASSF8 | 3.24e+00 | 2.49e-03 | 4.52e+00 | 9.91e-01 | Female-biased |
| DLBC | MEF2B | RASSF8 | 3.30e+00 | 3.17e-03 | 4.51e+00 | 9.90e-01 | Female-biased |
| DLBC | MEF2D | RASSF8 | 2.73e+00 | 2.02e-03 | 4.05e+00 | 9.84e-01 | Female-biased |
| DLBC | NFATC1 | RASSF8 | 3.00e+00 | 3.36e-03 | 4.19e+00 | 9.86e-01 | Female-biased |
| DLBC | NFATC2 | RASSF8 | 2.95e+00 | 3.60e-03 | 4.11e+00 | 9.84e-01 | Female-biased |
| DLBC | NFATC4 | RASSF8 | 3.30e+00 | 5.59e-03 | 4.35e+00 | 9.86e-01 | Female-biased |
| DLBC | NKX3-1 | RASSF8 | 3.06e+00 | 1.72e-03 | 4.44e+00 | 9.91e-01 | Female-biased |
| DLBC | NKX6-1 | RASSF8 | 2.55e+00 | 1.80e-03 | 3.91e+00 | 9.81e-01 | Female-biased |
| DLBC | OVOL2 | RASSF8 | 6.78e+00 | 1.75e-02 | 7.53e+00 | 9.82e-01 | Female-biased |
| DLBC | PHOX2A | RASSF8 | 3.38e+00 | 2.49e-03 | 4.66e+00 | 9.92e-01 | Female-biased |
| DLBC | PHOX2B | RASSF8 | 3.09e+00 | 1.81e-03 | 4.47e+00 | 9.91e-01 | Female-biased |
| DLBC | POU2F1 | RASSF8 | 2.82e+00 | 2.39e-03 | 4.10e+00 | 9.85e-01 | Female-biased |
| DLBC | POU3F2 | RASSF8 | 2.79e+00 | 2.33e-03 | 4.08e+00 | 9.85e-01 | Female-biased |
| DLBC | PROP1 | RASSF8 | 3.63e+00 | 3.23e-03 | 4.84e+00 | 9.93e-01 | Female-biased |
| DLBC | PRRX1 | RASSF8 | 3.18e+00 | 1.64e-03 | 4.59e+00 | 9.93e-01 | Female-biased |
| DLBC | SOX10 | RASSF8 | 2.77e+00 | 1.47e-03 | 4.19e+00 | 9.88e-01 | Female-biased |
| DLBC | SOX14 | RASSF8 | 2.98e+00 | 3.43e-03 | 4.16e+00 | 9.85e-01 | Female-biased |
| DLBC | SOX2 | RASSF8 | 3.13e+00 | 2.83e-03 | 4.37e+00 | 9.89e-01 | Female-biased |
| DLBC | SOX21 | RASSF8 | 2.97e+00 | 2.74e-03 | 4.22e+00 | 9.87e-01 | Female-biased |
| DLBC | SOX4 | RASSF8 | 2.76e+00 | 2.89e-03 | 3.98e+00 | 9.82e-01 | Female-biased |
| DLBC | SOX7 | RASSF8 | 2.88e+00 | 2.52e-03 | 4.15e+00 | 9.86e-01 | Female-biased |
| DLBC | SOX8 | RASSF8 | 2.69e+00 | 2.04e-03 | 4.02e+00 | 9.83e-01 | Female-biased |
| DLBC | SOX9 | RASSF8 | 2.70e+00 | 1.23e-03 | 4.18e+00 | 9.88e-01 | Female-biased |
| DLBC | TBP | RASSF8 | 2.88e+00 | 2.70e-03 | 4.13e+00 | 9.85e-01 | Female-biased |
| DLBC | UNCX | RASSF8 | 3.20e+00 | 2.77e-03 | 4.45e+00 | 9.90e-01 | Female-biased |
| DLBC | ZNF235 | RASSF8 | 3.98e+00 | 9.83e-01 | 2.55e+00 | 1.11e-03 | Male-biased |
| DLBC | ZNF25 | RASSF8 | 2.70e+00 | 2.51e-03 | 3.96e+00 | 9.82e-01 | Female-biased |
| DLBC | ZNF334 | RASSF8 | 2.62e+00 | 1.24e-03 | 4.09e+00 | 9.86e-01 | Female-biased |
| DLBC | ZNF35 | RASSF8 | 2.88e+00 | 3.25e-03 | 4.07e+00 | 9.83e-01 | Female-biased |
| DLBC | ZNF584 | RASSF8 | 2.61e+00 | 1.38e-03 | 4.04e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF653 | RASSF8 | 4.06e+00 | 8.36e-03 | 5.01e+00 | 9.89e-01 | Female-biased |
| DLBC | ZZZ3 | RASSF8 | 3.36e+00 | 6.95e-03 | 4.35e+00 | 9.85e-01 | Female-biased |
| SARC | POU3F2 | RASSF8 | 4.29e+00 | 9.85e-01 | 3.60e+00 | 4.66e-03 | Male-biased |
| SARC | ZNF334 | RASSF8 | 4.28e+00 | 9.82e-01 | 3.68e+00 | 7.68e-03 | Male-biased |
| RASSF8 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for RASSF8 |
| RBPs related to ES in RASSF8. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| RASSF8 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000123094 | AL513534.2,hsa-mir-410,RASSF8 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000123094 | AC021851.1,hsa-mir-410,RASSF8 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000123094 | AL021368.2,hsa-mir-410,RASSF8 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000123094 | TNFRSF10A-AS1,hsa-mir-410,RASSF8 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000123094 | AL031985.3,hsa-mir-410,RASSF8 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000123094 | SNHG29,hsa-mir-410,RASSF8 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000123094 | LINC01016,hsa-mir-203a,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000123094 | LINC01649,hsa-mir-31,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000123094 | AC016705.2,hsa-mir-31,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000123094 | LINC01116,hsa-mir-31,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000123094 | AP000688.2,hsa-mir-497,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000123094 | AL445309.1,hsa-mir-497,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000123094 | AL162377.1,hsa-mir-497,RASSF8 | Male-specific ceRNA | TCGA-KIRP |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs16920458 | chr12:32977158:T:C | - | 0.21708980407368 | 0.0122284279138363 | GBM | Female-baised eQTL |
| rs1500053 | chr12:32992881:C:G | - | 0.207864359542544 | 0.0241223513874674 | GBM | Female-baised eQTL |
| rs12578228 | chr12:32986327:C:T | - | 0.214397625501922 | 0.0251333716622008 | GBM | Female-baised eQTL |
| rs72640188 | chr12:32999159:G:A | - | 0.214397625501922 | 0.0251333716622008 | GBM | Female-baised eQTL |
| rs12579660 | chr12:33002301:T:C | - | 0.214397625501922 | 0.0251333716622008 | GBM | Female-baised eQTL |
| rs7956401 | chr12:24591171:A:G | - | 0.216893630121282 | 0.0388361315528929 | GBM | Female-baised eQTL |
| rs10843336 | chr12:29159260:C:T | - | 0.163730160241968 | 1.12035962665064e-05 | STAD | Female-baised eQTL |
| rs12229047 | chr12:26392885:G:A | - | 0.141560101344047 | 7.55192438923902e-05 | STAD | Female-baised eQTL |
| rs56024482 | chr12:29203861:G:A | - | 0.151160084527234 | 0.000181404522446802 | STAD | Female-baised eQTL |
| rs7309466 | chr12:29181235:G:C | - | 0.122217341600351 | 0.000733529428228707 | STAD | Female-baised eQTL |
| rs7135214 | chr12:33306543:G:A | - | 0.124282650653277 | 0.00203178043702069 | STAD | Female-baised eQTL |
| rs78867259 | chr12:25898317:C:G | - | 0.110496349333841 | 0.00529433233584996 | STAD | Female-baised eQTL |
| rs12833837 | chr12:26383470:G:T | - | 0.106513389104575 | 0.00539325506750416 | STAD | Female-baised eQTL |
| rs11050125 | chr12:29205068:A:G | - | 0.0962477324818433 | 0.0117395999960969 | STAD | Female-baised eQTL |
| rs12581588 | chr12:29206065:G:A | - | 0.0913343097171925 | 0.0208867384861268 | STAD | Female-baised eQTL |
| rs11050129 | chr12:29210661:A:T | - | 0.0866815399928493 | 0.0355267707704785 | STAD | Female-baised eQTL |
| rs4931260 | chr12:27675675:A:G | - | -0.0669712193717802 | 0.0469560131492485 | STAD | Female-baised eQTL |
| rs10734793 | chr12:30740566:T:C | - | 0.0893988433418942 | 0.035345387306063 | KIRC | Female-baised eQTL |
| rs12320609 | chr12:30737069:G:A | - | 0.0870213630071928 | 0.0389543858600029 | KIRC | Female-baised eQTL |
| rs10843819 | chr12:30714469:C:T | - | 0.086901110591206 | 0.0442809468008401 | KIRC | Female-baised eQTL |
| rs10843820 | chr12:30714860:C:T | - | 0.086901110591206 | 0.0442809468008401 | KIRC | Female-baised eQTL |
| rs11835180 | chr12:30738344:G:A | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs10843827 | chr12:30739271:C:G | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs10843828 | chr12:30739465:A:C | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs10843829 | chr12:30739632:G:A | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs7958274 | chr12:30740162:G:A | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs7958276 | chr12:30740173:G:A | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs10843831 | chr12:30742317:T:C | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs10843832 | chr12:30742532:C:T | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs11051049 | chr12:30743441:A:G | - | 0.0875478451649815 | 0.0471070802255347 | KIRC | Female-baised eQTL |
| rs10843818 | chr12:30714068:T:C | - | 0.0866158703853202 | 0.0472987018591536 | KIRC | Female-baised eQTL |
| rs10843821 | chr12:30724101:C:A | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs7299800 | chr12:30724457:G:T | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs11051045 | chr12:30725795:T:C | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs10843822 | chr12:30726154:T:C | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs10771761 | chr12:30727171:G:A | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs6487934 | chr12:30728362:G:A | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs6487935 | chr12:30728415:T:C | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs6487936 | chr12:30728416:G:A | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs10843824 | chr12:30732532:T:C | - | 0.0863301809048382 | 0.0473194573020388 | KIRC | Female-baised eQTL |
| rs12826341 | chr12:27910062:C:A | - | -0.13991892021228 | 0.0485951945805714 | BLCA | Female-baised eQTL |
| rs12832168 | chr12:27910360:G:A | - | -0.13991892021228 | 0.0485951945805714 | BLCA | Female-baised eQTL |
| rs7961917 | chr12:27903182:G:T | - | -0.163110669762184 | 0.0499552383961265 | BLCA | Female-baised eQTL |
| rs16933427 | chr12:28849337:G:A | - | 0.0894704616985655 | 0.00171429712635818 | LUAD | Female-baised eQTL |
| rs73084009 | chr12:28727817:A:G | - | 0.0726668289803847 | 0.0113827486836055 | LUAD | Female-baised eQTL |
| rs12371600 | chr12:16683048:C:A | - | 0.0569724601425551 | 0.0131763650991431 | LUAD | Female-baised eQTL |
| rs10841277 | chr12:19590789:G:C | - | 0.0633620991747393 | 0.0237942036244256 | LUAD | Female-baised eQTL |
| rs9738365 | chr12:31844701:C:A | - | 0.0440925607193589 | 0.0274036965926801 | LUAD | Female-baised eQTL |
| rs7970493 | chr12:21345542:A:T | - | 0.0499515778446339 | 0.0406810889320483 | LUAD | Female-baised eQTL |
| rs73076725 | chr12:19582953:G:A | - | 0.0507755892868184 | 0.0412662489217546 | LUAD | Female-baised eQTL |
| rs12318812 | chr12:19589293:A:T | - | 0.049162172116772 | 0.0483475709888854 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs117759352 | chr12:25168072:C:T | - | 0.0887549121672992 | 8.47189836536745e-06 | LIHC | Male-baised eQTL |
| rs17328054 | chr12:25124314:A:T | - | 0.0887511419574149 | 8.47947903175105e-06 | LIHC | Male-baised eQTL |
| rs73081725 | chr12:25126820:C:T | - | 0.0887511419574149 | 8.47947903175105e-06 | LIHC | Male-baised eQTL |
| rs73067300 | chr12:25133440:G:A | - | 0.0887511419574149 | 8.47947903175105e-06 | LIHC | Male-baised eQTL |
| rs17520989 | chr12:30243638:G:C | - | 0.0712147985206935 | 0.000337224652071904 | LIHC | Male-baised eQTL |
| rs11047893 | chr12:25212044:T:C | - | 0.0631405615487425 | 0.00168668001328975 | LIHC | Male-baised eQTL |
| rs10842507 | chr12:25216232:G:T | - | 0.0631405615487425 | 0.00168668001328975 | LIHC | Male-baised eQTL |
| rs139347675 | chr12:26057906:G:T | gene | 0.0593320833485177 | 0.00240788319151658 | LIHC | Male-baised eQTL |
| rs11048395 | chr12:26059767:C:A | gene | 0.056814080147415 | 0.00390584728156466 | LIHC | Male-baised eQTL |
| rs11048396 | chr12:26061655:C:T | gene | 0.056814080147415 | 0.00390584728156466 | LIHC | Male-baised eQTL |
| rs17354107 | chr12:25977964:G:A | gene | 0.0535957171354819 | 0.00665201790771716 | LIHC | Male-baised eQTL |
| rs67447248 | chr12:27527622:G:T | - | 0.054757464082253 | 0.00677672423998272 | LIHC | Male-baised eQTL |
| rs73077123 | chr12:25979689:G:C | gene | 0.0511917025110566 | 0.0103869916846236 | LIHC | Male-baised eQTL |
| rs17354204 | chr12:25978612:A:G | gene | 0.0510795104257458 | 0.0107497928187073 | LIHC | Male-baised eQTL |
| rs17354478 | chr12:25982580:G:C | gene | 0.0499655930900128 | 0.0129429378239615 | LIHC | Male-baised eQTL |
| rs2643932 | chr12:25912050:G:A | - | 0.0539229890817963 | 0.014745827160873 | LIHC | Male-baised eQTL |
| rs10219479 | chr12:25983824:G:C | gene | 0.0465589404330901 | 0.0221012009186203 | LIHC | Male-baised eQTL |
| rs60218193 | chr12:27530312:A:C | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs59176058 | chr12:27530767:C:T | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs57662555 | chr12:27530858:G:A | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs57426538 | chr12:27530859:C:T | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs60770761 | chr12:27530875:A:C | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs73087747 | chr12:27531200:C:T | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs67007118 | chr12:27531212:G:A | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs7959388 | chr12:27531778:A:C | - | 0.043763724363901 | 0.0321821373525561 | LIHC | Male-baised eQTL |
| rs112973769 | chr12:27545308:A:C | - | 0.0434236277772808 | 0.0325515954941872 | LIHC | Male-baised eQTL |
| rs56161394 | chr12:27542286:A:G | - | 0.0432883163884992 | 0.0337498442535365 | LIHC | Male-baised eQTL |
| rs67003520 | chr12:27533418:C:T | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs73087752 | chr12:27533463:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67411250 | chr12:27533745:T:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67841159 | chr12:27533984:T:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67718612 | chr12:27534027:G:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs73306341 | chr12:27534147:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs66774511 | chr12:27534241:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67318133 | chr12:27534643:T:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs7971294 | chr12:27534781:A:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs66491775 | chr12:27535086:G:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs7961615 | chr12:27535373:T:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs7961856 | chr12:27535533:T:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs7975462 | chr12:27535633:G:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs66549670 | chr12:27535958:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs73089586 | chr12:27536005:C:T | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs66467962 | chr12:27536012:C:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs56831703 | chr12:27536190:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs58872083 | chr12:27536321:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs57563323 | chr12:27536359:T:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs56215075 | chr12:27536747:G:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs55642897 | chr12:27536988:T:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs57479422 | chr12:27537333:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs61160480 | chr12:27537396:G:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67466800 | chr12:27537672:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67992105 | chr12:27537741:G:T | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs66493962 | chr12:27538178:C:T | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67079938 | chr12:27538230:A:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs66913539 | chr12:27538340:C:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs56989163 | chr12:27538783:A:G | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs56260309 | chr12:27539817:G:A | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs67813594 | chr12:27540764:T:C | - | 0.0426552317658051 | 0.0362099954609085 | LIHC | Male-baised eQTL |
| rs4099930 | chr12:30272586:G:T | - | 0.0401299730141322 | 0.0387653713263791 | LIHC | Male-baised eQTL |
| rs67259088 | chr12:27545442:G:C | - | 0.0423889013454708 | 0.0390410969050774 | LIHC | Male-baised eQTL |
| rs7968760 | chr12:30637463:C:T | - | 0.03647119419119 | 0.0471411904041083 | LIHC | Male-baised eQTL |
| rs61923499 | chr12:22850297:C:A | - | 0.0473991681884411 | 0.0433641611374641 | LGG | Male-baised eQTL |
| rs1823924 | chr12:32823287:T:C | - | -0.064004248197999 | 0.00117953423288448 | BLCA | Male-baised eQTL |
| rs2022140 | chr12:32819244:T:C | - | -0.0628635368750148 | 0.00147313812434145 | BLCA | Male-baised eQTL |
| rs7308045 | chr12:32819461:A:C | - | -0.0628635368750148 | 0.00147313812434145 | BLCA | Male-baised eQTL |
| rs187875681 | chr12:20989445:C:A | - | 0.101945849591412 | 0.00550921520269714 | BLCA | Male-baised eQTL |
| rs59867329 | chr12:20984551:G:C | - | 0.0961909314380085 | 0.0109379018610716 | BLCA | Male-baised eQTL |
| rs202169512 | chr12:20982627:G:A | - | 0.0931175110929046 | 0.0144637096195424 | BLCA | Male-baised eQTL |
| rs11050870 | chr12:30384887:C:A | - | -0.0398010452702294 | 0.0217649010358457 | BLCA | Male-baised eQTL |
| rs1124251 | chr12:20988443:G:A | - | 0.0459777934193592 | 0.0239367099864986 | BLCA | Male-baised eQTL |
| rs2012291 | chr12:29275489:G:T | - | 0.078995952649941 | 0.025414288688626 | BLCA | Male-baised eQTL |
| rs2933405 | chr12:31132167:A:G | - | -0.0589679393752235 | 0.0257756384798339 | BLCA | Male-baised eQTL |
| rs10841717 | chr12:20951145:C:T | - | -0.0449992708003485 | 0.026772580915792 | BLCA | Male-baised eQTL |
| rs7139305 | chr12:29281786:T:A | - | 0.0785829501878692 | 0.0269786511729781 | BLCA | Male-baised eQTL |
| rs4617642 | chr12:20956801:G:T | - | -0.0437947135929249 | 0.033118149656765 | BLCA | Male-baised eQTL |
| rs78480710 | chr12:29275074:C:T | - | 0.0757233095169274 | 0.0365392721061316 | BLCA | Male-baised eQTL |
| rs4992973 | chr12:29275442:C:T | - | 0.0757233095169274 | 0.0365392721061316 | BLCA | Male-baised eQTL |
| rs61922001 | chr12:30388121:C:T | - | -0.0381195151441966 | 0.03747243972046 | BLCA | Male-baised eQTL |
| rs28591644 | chr12:30388122:A:T | - | -0.0381195151441966 | 0.03747243972046 | BLCA | Male-baised eQTL |
| rs11045631 | chr12:20973917:T:C | - | 0.0421918668916865 | 0.0437278199627483 | BLCA | Male-baised eQTL |
| rs10771725 | chr12:30463113:C:T | - | -0.0359313924302972 | 0.0451709333868138 | BLCA | Male-baised eQTL |
| rs11050868 | chr12:30381346:A:T | - | -0.0376307562434124 | 0.0453042393586961 | BLCA | Male-baised eQTL |
| rs10450678 | chr12:21097413:G:A | - | 0.0786092168881575 | 0.0462843244316516 | BLCA | Male-baised eQTL |
| rs11045748 | chr12:21092446:G:T | - | 0.0799996527254562 | 0.0476616523816557 | BLCA | Male-baised eQTL |
| rs7306941 | chr12:30400244:G:A | - | -0.0373031853983669 | 0.0481306482631224 | BLCA | Male-baised eQTL |
| rs978711 | chr12:30400361:T:C | - | -0.0373031853983669 | 0.0481306482631224 | BLCA | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000123094 |
| CpG Site: cg21373145 | |
| Position to Gene: promoter | |
| Male Effect: -0.402319739083349 | |
| Female Effect: - | |
 | Gene ID: ENSG00000123094 |
| CpG Site: cg15282709 | |
| Position to Gene: promoter | |
| Male Effect: -0.430063998059431 | |
| Female Effect: - | |
 | Gene ID: ENSG00000123094 |
| CpG Site: cg09411682 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.244211877881421 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg21373145 | chr12:25957733 | promoter | -0.402319739083349 | 1.15985087891132e-08 | -0.43004562283666004 | 1.879458419295939e-11 | LUAD |
| cg15282709 | chr12:25957767 | promoter | -0.430063998059431 | 3.77625019566372e-10 | -0.40263148684680616 | 2.5795571384860226e-13 | BLCA |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg09411682 | chr12:25992451 | gene | -0.244211877881421 | 4.17569886885453e-05 | -0.4453933826250302 | 6.949227539021379e-08 | HNSC |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of RASSF8 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000123094 | RASSF8 | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
