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Gene: ENSG00000121858 |
Summary for TNFSF10 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000121858 | Gene symbol | TNFSF10 |
| Gene name | TNF superfamily member 10 | |
| HGNC | 11925 | |
| Entrez ID | 8743 | |
| Gene type | protein_coding | |
| Synonyms | TNFSF10|TRAIL|Apo-2L|TL2|CD253 | |
| UniProtAcc | P50591 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for TNFSF10 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TNFSF10 | 7.64e+03 | 1.66e+00 | 4.88e-01 | 3.41e+00 | 6.54e-04 | 2.30e-03 | BLCA |
| TNFSF10 | 1.97e+04 | 1.57e+00 | 2.36e-01 | 6.64e+00 | 3.20e-11 | 2.26e-10 | KIRP |
| TNFSF10 | 1.03e+04 | 1.65e+00 | 4.32e-01 | 3.82e+00 | 1.32e-04 | 1.25e-03 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TNFSF10 | 1.54e+04 | 1.04e+00 | 2.91e-01 | 3.56e+00 | 3.70e-04 | 1.80e-03 | HNSC |
| TNFSF10 | 2.36e+03 | -1.23e+00 | 3.07e-01 | -4.02e+00 | 5.92e-05 | 3.04e-04 | READ |
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Sex-biased somatic mutation for TNFSF10 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for TNFSF10 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg21402832 | chr3:172523279 | CGI:chr3:172449736-172450076 | promoter,exon,CDS,gene body | 7.18e-02 | 1.80e-01 | -4.03e+00 | 5.69e-05 | 2.70e-04 | -1.08e-01 |
| KIRP | cg22572614 | chr3:172524185 | CGI:chr3:172449736-172450076 | promoter | 6.56e-01 | 8.63e-01 | -3.12e+00 | 1.81e-03 | 3.01e-03 | -2.07e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg22572614 | chr3:172524185 | CGI:chr3:172449736-172450076 | promoter | 9.18e-01 | 8.10e-01 | 3.04e+00 | 2.35e-03 | 1.02e-02 | 1.08e-01 |
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Exon skipping events with PSI in TCGA for TNFSF10 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for TNFSF10 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for TNFSF10 |
| TFs related to TNFSF10. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | CDX2 | TNFSF10 | 3.04e+00 | 5.34e-03 | 4.12e+00 | 9.84e-01 | Female-biased |
| CHOL | DMRT3 | TNFSF10 | 3.88e+00 | 4.15e-03 | 5.04e+00 | 9.93e-01 | Female-biased |
| CHOL | DMRTA1 | TNFSF10 | 3.63e+00 | 6.26e-03 | 4.69e+00 | 9.89e-01 | Female-biased |
| CHOL | DMRTA2 | TNFSF10 | 3.65e+00 | 4.82e-03 | 4.78e+00 | 9.91e-01 | Female-biased |
| CHOL | EVX2 | TNFSF10 | 3.20e+00 | 8.15e-03 | 4.18e+00 | 9.82e-01 | Female-biased |
| CHOL | FOXF1 | TNFSF10 | 3.22e+00 | 5.93e-03 | 4.28e+00 | 9.86e-01 | Female-biased |
| CHOL | HOXC10 | TNFSF10 | 3.10e+00 | 3.72e-03 | 4.28e+00 | 9.88e-01 | Female-biased |
| CHOL | TBP | TNFSF10 | 3.15e+00 | 7.02e-03 | 4.17e+00 | 9.83e-01 | Female-biased |
| CHOL | ZNF33B | TNFSF10 | 3.18e+00 | 8.90e-03 | 4.14e+00 | 9.81e-01 | Female-biased |
| CHOL | ZNF580 | TNFSF10 | 3.46e+00 | 4.42e-03 | 4.60e+00 | 9.91e-01 | Female-biased |
| DLBC | CDX2 | TNFSF10 | 3.35e+00 | 6.29e-03 | 4.37e+00 | 9.86e-01 | Female-biased |
| DLBC | DMRT3 | TNFSF10 | 4.19e+00 | 1.49e-02 | 4.98e+00 | 9.82e-01 | Female-biased |
| DLBC | DMRTA1 | TNFSF10 | 3.84e+00 | 8.53e-03 | 4.78e+00 | 9.87e-01 | Female-biased |
| DLBC | DMRTA2 | TNFSF10 | 3.94e+00 | 1.10e-02 | 4.82e+00 | 9.85e-01 | Female-biased |
| DLBC | FOXF1 | TNFSF10 | 3.53e+00 | 8.46e-03 | 4.47e+00 | 9.85e-01 | Female-biased |
| DLBC | FOXG1 | TNFSF10 | 2.65e+00 | 1.83e-03 | 4.01e+00 | 9.84e-01 | Female-biased |
| DLBC | FOXL1 | TNFSF10 | 2.53e+00 | 1.03e-03 | 4.06e+00 | 9.86e-01 | Female-biased |
| DLBC | HOXC10 | TNFSF10 | 3.48e+00 | 1.01e-02 | 4.38e+00 | 9.82e-01 | Female-biased |
| DLBC | MYNN | TNFSF10 | 3.31e+00 | 6.31e-03 | 4.32e+00 | 9.85e-01 | Female-biased |
| DLBC | STAT2 | TNFSF10 | 2.40e+00 | 6.84e-04 | 4.06e+00 | 9.86e-01 | Female-biased |
| DLBC | ZKSCAN2 | TNFSF10 | 3.39e+00 | 4.63e-03 | 4.49e+00 | 9.89e-01 | Female-biased |
| DLBC | ZNF333 | TNFSF10 | 4.02e+00 | 9.83e-01 | 2.68e+00 | 1.49e-03 | Male-biased |
| DLBC | ZNF33B | TNFSF10 | 3.38e+00 | 4.83e-03 | 4.47e+00 | 9.88e-01 | Female-biased |
| DLBC | ZNF45 | TNFSF10 | 3.40e+00 | 8.51e-03 | 4.34e+00 | 9.83e-01 | Female-biased |
| DLBC | ZNF580 | TNFSF10 | 3.67e+00 | 4.85e-03 | 4.77e+00 | 9.91e-01 | Female-biased |
| PAAD | BCL11A | TNFSF10 | 4.14e+00 | 9.87e-01 | 2.90e+00 | 1.18e-03 | Male-biased |
| PAAD | CDX2 | TNFSF10 | 4.36e+00 | 9.90e-01 | 3.16e+00 | 1.53e-03 | Male-biased |
| PAAD | DMRT3 | TNFSF10 | 5.08e+00 | 9.94e-01 | 4.00e+00 | 2.82e-03 | Male-biased |
| PAAD | DMRTA1 | TNFSF10 | 4.85e+00 | 9.94e-01 | 3.74e+00 | 2.51e-03 | Male-biased |
| PAAD | DMRTA2 | TNFSF10 | 4.92e+00 | 9.94e-01 | 3.84e+00 | 2.86e-03 | Male-biased |
| PAAD | ELF5 | TNFSF10 | 4.37e+00 | 9.89e-01 | 3.28e+00 | 2.68e-03 | Male-biased |
| PAAD | EVX2 | TNFSF10 | 4.46e+00 | 9.91e-01 | 3.28e+00 | 1.73e-03 | Male-biased |
| PAAD | FOXF1 | TNFSF10 | 4.48e+00 | 9.92e-01 | 3.23e+00 | 1.17e-03 | Male-biased |
| PAAD | FOXG1 | TNFSF10 | 4.14e+00 | 9.88e-01 | 2.68e+00 | 3.63e-04 | Male-biased |
| PAAD | FOXL1 | TNFSF10 | 3.85e+00 | 9.81e-01 | 2.47e+00 | 5.52e-04 | Male-biased |
| PAAD | GATA2 | TNFSF10 | 4.41e+00 | 9.89e-01 | 3.35e+00 | 3.19e-03 | Male-biased |
| PAAD | GATA4 | TNFSF10 | 4.68e+00 | 9.93e-01 | 3.49e+00 | 1.62e-03 | Male-biased |
| PAAD | HMBOX1 | TNFSF10 | 6.26e+00 | 9.83e-01 | 5.51e+00 | 1.60e-02 | Male-biased |
| PAAD | HOXC10 | TNFSF10 | 4.42e+00 | 9.91e-01 | 3.24e+00 | 1.74e-03 | Male-biased |
| PAAD | MYNN | TNFSF10 | 4.45e+00 | 9.92e-01 | 3.17e+00 | 1.04e-03 | Male-biased |
| PAAD | OSR1 | TNFSF10 | 5.28e+00 | 9.85e-01 | 4.49e+00 | 1.25e-02 | Male-biased |
| PAAD | SPIC | TNFSF10 | 4.26e+00 | 9.88e-01 | 3.10e+00 | 1.79e-03 | Male-biased |
| PAAD | SRF | TNFSF10 | 5.26e+00 | 9.96e-01 | 4.14e+00 | 2.30e-03 | Male-biased |
| PAAD | STAT2 | TNFSF10 | 4.06e+00 | 9.86e-01 | 2.65e+00 | 4.73e-04 | Male-biased |
| PAAD | STAT4 | TNFSF10 | 4.06e+00 | 9.81e-01 | 3.13e+00 | 5.95e-03 | Male-biased |
| PAAD | STAT5B | TNFSF10 | 4.54e+00 | 9.91e-01 | 3.45e+00 | 2.70e-03 | Male-biased |
| PAAD | TAL1 | TNFSF10 | 4.51e+00 | 9.82e-01 | 3.70e+00 | 1.14e-02 | Male-biased |
| PAAD | TBP | TNFSF10 | 4.36e+00 | 9.89e-01 | 3.24e+00 | 2.21e-03 | Male-biased |
| PAAD | ZFP69 | TNFSF10 | 4.05e+00 | 9.81e-01 | 3.11e+00 | 5.65e-03 | Male-biased |
| PAAD | ZKSCAN2 | TNFSF10 | 4.49e+00 | 9.92e-01 | 3.21e+00 | 9.99e-04 | Male-biased |
| PAAD | ZNF135 | TNFSF10 | 4.33e+00 | 9.85e-01 | 3.40e+00 | 6.12e-03 | Male-biased |
| PAAD | ZNF184 | TNFSF10 | 4.36e+00 | 9.88e-01 | 3.34e+00 | 3.88e-03 | Male-biased |
| PAAD | ZNF33B | TNFSF10 | 4.57e+00 | 9.94e-01 | 3.10e+00 | 3.67e-04 | Male-biased |
| PAAD | ZNF45 | TNFSF10 | 4.36e+00 | 9.88e-01 | 3.31e+00 | 3.30e-03 | Male-biased |
| PAAD | ZNF485 | TNFSF10 | 4.18e+00 | 9.83e-01 | 3.23e+00 | 5.36e-03 | Male-biased |
| PAAD | ZNF562 | TNFSF10 | 4.54e+00 | 9.80e-01 | 3.76e+00 | 1.33e-02 | Male-biased |
| PAAD | ZNF580 | TNFSF10 | 4.82e+00 | 9.95e-01 | 3.41e+00 | 5.07e-04 | Male-biased |
| PAAD | ZNF71 | TNFSF10 | 4.54e+00 | 9.93e-01 | 3.14e+00 | 5.42e-04 | Male-biased |
| SARC | CDX2 | TNFSF10 | 2.81e+00 | 1.14e-03 | 3.85e+00 | 9.80e-01 | Female-biased |
| SARC | DMRT3 | TNFSF10 | 3.76e+00 | 3.06e-03 | 4.62e+00 | 9.92e-01 | Female-biased |
| SARC | DMRTA1 | TNFSF10 | 3.41e+00 | 1.97e-03 | 4.34e+00 | 9.90e-01 | Female-biased |
| SARC | DMRTA2 | TNFSF10 | 3.55e+00 | 2.43e-03 | 4.45e+00 | 9.91e-01 | Female-biased |
| SARC | FOXF1 | TNFSF10 | 3.00e+00 | 1.01e-03 | 4.06e+00 | 9.86e-01 | Female-biased |
| SARC | GATA2 | TNFSF10 | 3.45e+00 | 6.77e-03 | 4.16e+00 | 9.82e-01 | Female-biased |
| SARC | GATA4 | TNFSF10 | 3.57e+00 | 5.20e-03 | 4.33e+00 | 9.86e-01 | Female-biased |
| SARC | HMBOX1 | TNFSF10 | 5.53e+00 | 1.31e-02 | 6.13e+00 | 9.86e-01 | Female-biased |
| SARC | HOMEZ | TNFSF10 | 5.86e+00 | 1.56e-02 | 6.43e+00 | 9.84e-01 | Female-biased |
| SARC | HOXC10 | TNFSF10 | 2.98e+00 | 1.99e-03 | 3.91e+00 | 9.81e-01 | Female-biased |
| SARC | HOXD11 | TNFSF10 | 5.98e+00 | 1.35e-02 | 6.58e+00 | 9.86e-01 | Female-biased |
| SARC | MYNN | TNFSF10 | 2.85e+00 | 1.22e-03 | 3.87e+00 | 9.81e-01 | Female-biased |
| SARC | OSR1 | TNFSF10 | 4.55e+00 | 1.43e-02 | 5.13e+00 | 9.83e-01 | Female-biased |
| SARC | SPIC | TNFSF10 | 3.14e+00 | 3.50e-03 | 3.96e+00 | 9.81e-01 | Female-biased |
| SARC | SRF | TNFSF10 | 4.08e+00 | 3.24e-03 | 4.93e+00 | 9.94e-01 | Female-biased |
| SARC | STAT5B | TNFSF10 | 3.47e+00 | 3.93e-03 | 4.28e+00 | 9.87e-01 | Female-biased |
| SARC | TBP | TNFSF10 | 3.10e+00 | 2.41e-03 | 3.99e+00 | 9.83e-01 | Female-biased |
| SARC | ZKSCAN2 | TNFSF10 | 2.88e+00 | 1.18e-03 | 3.91e+00 | 9.82e-01 | Female-biased |
| SARC | ZNF33B | TNFSF10 | 2.88e+00 | 7.91e-04 | 3.98e+00 | 9.84e-01 | Female-biased |
| SARC | ZNF580 | TNFSF10 | 3.28e+00 | 1.98e-03 | 4.22e+00 | 9.88e-01 | Female-biased |
| SARC | ZNF71 | TNFSF10 | 3.28e+00 | 3.46e-03 | 4.11e+00 | 9.84e-01 | Female-biased |
| TNFSF10 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for TNFSF10 |
| RBPs related to ES in TNFSF10. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | PABPN1 | exon_skip_390068 | 7.10e+00 | 6.91e-03 | 7.45e+00 | 9.82e-01 | Female-biased |
| CHOL | FXR1 | exon_skip_390084 | 1.06e+01 | 9.90e-01 | 1.02e+01 | 8.59e-03 | Male-biased |
| SARC | FXR1 | exon_skip_390084 | 1.01e+01 | 1.15e-02 | 1.04e+01 | 9.87e-01 | Female-biased |
| TNFSF10 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000121858 | LINC00240,hsa-mir-340,TNFSF10 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000121858 | AC012593.1,hsa-mir-340,TNFSF10 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000121858 | B3GALT5-AS1,hsa-mir-340,TNFSF10 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000121858 | AC099342.1,hsa-mir-340,TNFSF10 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000121858 | AC099521.1,hsa-mir-340,TNFSF10 | Male-specific ceRNA | TCGA-KIRP |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs145721547 | chr3:168133081:C:T | - | 0.0705928416580055 | 0.000326323304389454 | THCA | Female-baised eQTL |
| rs9869533 | chr3:174355190:G:T | - | 0.205260040018348 | 0.0314435479651299 | SARC | Female-baised eQTL |
| rs74756254 | chr3:182248049:G:T | - | 0.0468259173175725 | 0.0115474706041591 | LUAD | Female-baised eQTL |
| rs75955126 | chr3:182248847:A:G | - | 0.0466844102603123 | 0.0121020190845175 | LUAD | Female-baised eQTL |
| rs9849291 | chr3:174291553:G:C | - | 0.0356781788309679 | 0.0146426409839557 | LUAD | Female-baised eQTL |
| rs2172394 | chr3:171303967:A:G | - | 0.0395994590714515 | 0.0212829318457859 | LUAD | Female-baised eQTL |
| rs7636148 | chr3:182251506:C:T | - | 0.0416876352948076 | 0.0297720565418856 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1478146 | chr3:162525963:C:T | - | 0.238309328969065 | 0.0212224407140228 | READ | Male-baised eQTL |
| rs114921699 | chr3:162531333:T:A | - | 0.238309328969065 | 0.0212224407140228 | READ | Male-baised eQTL |
| rs12634933 | chr3:169312191:A:G | - | 0.154815075553892 | 0.00288027886417183 | SARC | Male-baised eQTL |
| rs16853486 | chr3:169314218:C:T | - | 0.154742658306313 | 0.00294402697288963 | SARC | Male-baised eQTL |
| rs9883505 | chr3:177542280:G:A | - | 0.179894041794746 | 0.00994500067706769 | SARC | Male-baised eQTL |
| rs59164328 | chr3:169313927:A:G | - | 0.129101280232193 | 0.0158771916882718 | SARC | Male-baised eQTL |
| rs56781999 | chr3:169313928:A:T | - | 0.129101280232193 | 0.0158771916882718 | SARC | Male-baised eQTL |
| rs16853481 | chr3:169313966:C:T | - | 0.129101280232193 | 0.0158771916882718 | SARC | Male-baised eQTL |
| rs16853483 | chr3:169314199:C:T | - | 0.129101280232193 | 0.0158771916882718 | SARC | Male-baised eQTL |
| rs12631188 | chr3:169314337:C:G | - | 0.129101280232193 | 0.0158771916882718 | SARC | Male-baised eQTL |
| rs12629452 | chr3:169308211:T:C | - | 0.117500065161359 | 0.0212383073378961 | SARC | Male-baised eQTL |
| rs16853470 | chr3:169308342:G:T | - | 0.117500065161359 | 0.0212383073378961 | SARC | Male-baised eQTL |
| rs60578369 | chr3:169308371:T:C | - | 0.117500065161359 | 0.0212383073378961 | SARC | Male-baised eQTL |
| rs11928517 | chr3:169310094:G:A | - | 0.112659081743889 | 0.0321096275441951 | SARC | Male-baised eQTL |
| rs73172243 | chr3:179502694:A:T | - | 0.0530194862719115 | 0.0182093167442982 | LUAD | Male-baised eQTL |
| rs73172231 | chr3:179478174:T:A | - | 0.0525450950488864 | 0.0209640425052734 | LUAD | Male-baised eQTL |
| rs73180015 | chr3:179992177:A:G | - | 0.0615460889977694 | 0.0260863193122764 | LUAD | Male-baised eQTL |
| rs73180017 | chr3:179992178:T:C | - | 0.0615460889977694 | 0.0260863193122764 | LUAD | Male-baised eQTL |
| rs75810415 | chr3:179499681:T:A | - | 0.0505705634285353 | 0.0345265962890293 | LUAD | Male-baised eQTL |
| rs112823316 | chr3:179481029:T:G | - | 0.0498210302406178 | 0.0427587840663795 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TNFSF10 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000121858 | TNFSF10 | C0000786 | Spontaneous abortion | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0000822 | Abortion, Tubal | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0007102 | Malignant tumor of colon | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0007134 | Renal Cell Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0009375 | Colonic Neoplasms | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0009402 | Colorectal Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0014170 | Endometrial Neoplasms | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0017636 | Glioblastoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0017638 | Glioma | 2 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0021400 | Influenza | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0022665 | Kidney Neoplasm | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0023418 | leukemia | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0023903 | Liver neoplasms | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0026998 | Acute Myeloid Leukemia, M1 | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0027659 | Neoplasms, Experimental | 2 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0027686 | Pathologic Neovascularization | 2 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0027819 | Neuroblastoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0030297 | Pancreatic Neoplasm | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0033578 | Prostatic Neoplasms | 4 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0259783 | mixed gliomas | 2 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0279702 | Conventional (Clear Cell) Renal Cell Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0334588 | Giant Cell Glioblastoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0345904 | Malignant neoplasm of liver | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0346647 | Malignant neoplasm of pancreas | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0376358 | Malignant neoplasm of prostate | 4 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0476089 | Endometrial Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0555198 | Malignant Glioma | 2 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0740457 | Malignant neoplasm of kidney | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C0919267 | ovarian neoplasm | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1140680 | Malignant neoplasm of ovary | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1266042 | Chromophobe Renal Cell Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1266043 | Sarcomatoid Renal Cell Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1266044 | Collecting Duct Carcinoma of the Kidney | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1306837 | Papillary Renal Cell Carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1621958 | Glioblastoma Multiforme | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C1879321 | Acute Myeloid Leukemia (AML-M2) | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C2239176 | Liver carcinoma | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C3830362 | Early Pregnancy Loss | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C4552766 | Miscarriage | 1 | CTD_human |
| ENSG00000121858 | TNFSF10 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
