|
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: ENSG00000119977 |
Summary for TCTN3 |
Gene summary |
| Gene information | Ensembl ID | ENSG00000119977 | Gene symbol | TCTN3 |
| Gene name | tectonic family member 3 | |
| HGNC | 24519 | |
| Entrez ID | 26123 | |
| Gene type | protein_coding | |
| Synonyms | TCTN3|DKFZP564D116|TECT3|JBTS18 | |
| UniProtAcc | Q6NUS6 |
Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TCTN3 |
AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
Landscape of gene expressions across multiple cancer types. |
Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for TCTN3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for TCTN3 |
Landscape of DNA methylation across multiple cancer types. |
Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for TCTN3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
Landscape of exon skipping events across multiple cancer types. |
Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for TCTN3 |
| ∗Please access CAeditome for RNA editing annotation. |
Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for TCTN3 |
TFs related to TCTN3.∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
TCTN3 related gene.∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for TCTN3 |
RBPs related to ES in TCTN3.∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| UVM | RBM6 | exon_skip_52508 | 7.90e+00 | 9.84e-01 | 7.58e+00 | 6.93e-03 | Male-biased |
| PAAD | RBM6 | exon_skip_52508 | 7.51e+00 | 6.98e-03 | 7.84e+00 | 9.84e-01 | Female-biased |
TCTN3 related ES.∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs61857570 | chr10:96442996:T:C | - | 0.254452687224318 | 2.93808035729803e-05 | BLCA | Female-baised eQTL |
| rs1902692 | chr10:86298020:A:G | - | 0.197705091848816 | 0.0002296897730867 | BLCA | Female-baised eQTL |
| rs34625348 | chr10:96427577:T:A | - | 0.240042731188738 | 0.000401551311996582 | BLCA | Female-baised eQTL |
| rs34812648 | chr10:96431925:G:A | - | 0.240042731188738 | 0.000401551311996582 | BLCA | Female-baised eQTL |
| rs12765987 | chr10:96428962:G:A | - | 0.232033032943935 | 0.000527583358638011 | BLCA | Female-baised eQTL |
| rs59643065 | chr10:86928292:A:G | - | 0.20513935133152 | 0.00153288797527827 | BLCA | Female-baised eQTL |
| rs12360052 | chr10:97486859:T:C | - | 0.12069617900305 | 0.0073919512656405 | BLCA | Female-baised eQTL |
| rs3740526 | chr10:97460950:C:T | - | 0.119241754528089 | 0.00819628269834276 | BLCA | Female-baised eQTL |
| rs12412017 | chr10:97474481:G:A | - | 0.119241754528089 | 0.00819628269834276 | BLCA | Female-baised eQTL |
| rs7923913 | chr10:97448706:C:T | - | 0.116652333453127 | 0.0104601616402515 | BLCA | Female-baised eQTL |
| rs12766149 | chr10:99171830:C:A | - | 0.225001219369241 | 0.0106126247617768 | BLCA | Female-baised eQTL |
| rs11189240 | chr10:97497155:G:A | - | 0.117461275272497 | 0.011546430178599 | BLCA | Female-baised eQTL |
| rs10882938 | chr10:97451461:C:G | - | 0.114926711593665 | 0.0119709598308649 | BLCA | Female-baised eQTL |
| rs7897727 | chr10:97480291:C:T | - | -0.112321129291865 | 0.0154161446295855 | BLCA | Female-baised eQTL |
| rs2007349 | chr10:97479964:C:T | - | -0.108600485617418 | 0.0279531448875437 | BLCA | Female-baised eQTL |
| rs4917773 | chr10:97490172:A:G | - | -0.108600485617418 | 0.0279531448875437 | BLCA | Female-baised eQTL |
| rs764223 | chr10:97432178:G:A | - | 0.110356873973396 | 0.033745796076668 | BLCA | Female-baised eQTL |
| rs1932797 | chr10:98500491:C:A | - | 0.319621454328413 | 0.0346040362828971 | BLCA | Female-baised eQTL |
| rs113203098 | chr10:98501987:C:T | - | 0.319621454328413 | 0.0346040362828971 | BLCA | Female-baised eQTL |
| rs7100305 | chr10:98503196:C:G | - | 0.319621454328413 | 0.0346040362828971 | BLCA | Female-baised eQTL |
| rs11189638 | chr10:98505644:C:T | - | 0.319621454328413 | 0.0346040362828971 | BLCA | Female-baised eQTL |
| rs10882942 | chr10:97483569:C:T | - | 0.108458889418814 | 0.0354968710669694 | BLCA | Female-baised eQTL |
| rs10160114 | chr10:98505087:T:C | - | 0.318135844257627 | 0.036732907823883 | BLCA | Female-baised eQTL |
| rs12355928 | chr10:99487794:C:T | - | 0.118577334612156 | 0.0454087738985375 | BLCA | Female-baised eQTL |
| rs1539433 | chr10:95759888:C:T | - | 0.0431382104735933 | 0.0357809769847326 | LUAD | Female-baised eQTL |
Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7077851 | chr10:86128546:T:C | - | 0.115744180354451 | 0.0311702335316294 | PAAD | Male-baised eQTL |
| rs6585995 | chr10:86128929:A:G | - | 0.115744180354451 | 0.0311702335316294 | PAAD | Male-baised eQTL |
| rs6585996 | chr10:86128951:G:A | - | 0.115744180354451 | 0.0311702335316294 | PAAD | Male-baised eQTL |
| rs6585997 | chr10:86129077:A:C | - | 0.115744180354451 | 0.0311702335316294 | PAAD | Male-baised eQTL |
| rs4934156 | chr10:86136650:A:G | - | 0.115744180354451 | 0.0311702335316294 | PAAD | Male-baised eQTL |
| rs10509531 | chr10:86138246:C:T | - | 0.115744180354451 | 0.0311702335316294 | PAAD | Male-baised eQTL |
| rs7921149 | chr10:86150190:T:C | - | 0.114662887507261 | 0.0376171078219948 | PAAD | Male-baised eQTL |
| rs7342091 | chr10:86140777:G:A | - | 0.111964469261138 | 0.0498874600698847 | PAAD | Male-baised eQTL |
| rs10887559 | chr10:86147333:G:A | - | 0.111964469261138 | 0.0498874600698847 | PAAD | Male-baised eQTL |
| rs10748591 | chr10:93084109:C:G | - | -0.066904191765124 | 0.0392345234927043 | STAD | Male-baised eQTL |
| rs17112444 | chr10:99990217:G:A | - | -0.0776233476444739 | 0.00568998435110206 | BLCA | Male-baised eQTL |
| rs7086484 | chr10:90773972:G:A | - | -0.0570849892259545 | 0.00577903547396594 | COAD | Male-baised eQTL |
| rs12783703 | chr10:90800656:A:G | - | -0.0507126434984197 | 0.0177170050865347 | COAD | Male-baised eQTL |
| rs58868307 | chr10:90807399:C:A | - | -0.0486518498616701 | 0.0320032131669579 | COAD | Male-baised eQTL |
| rs4350279 | chr10:90806414:C:T | - | -0.0485451773564856 | 0.0326884008681675 | COAD | Male-baised eQTL |
| rs4933607 | chr10:90785312:G:A | - | -0.0484586834625605 | 0.0328643551871992 | COAD | Male-baised eQTL |
| rs12412496 | chr10:90786408:G:A | - | -0.0484586834625605 | 0.0328643551871992 | COAD | Male-baised eQTL |
| rs4933608 | chr10:90800030:C:T | - | -0.0484586834625605 | 0.0328643551871992 | COAD | Male-baised eQTL |
| rs12785051 | chr10:90800571:T:A | - | -0.0484586834625605 | 0.0328643551871992 | COAD | Male-baised eQTL |
| rs12764938 | chr10:90800957:C:T | - | -0.0484586834625605 | 0.0328643551871992 | COAD | Male-baised eQTL |
| rs1418214 | chr10:90802620:C:A | - | -0.0484586834625605 | 0.0328643551871992 | COAD | Male-baised eQTL |
| rs36101610 | chr10:90781122:C:A | - | -0.0485485095792767 | 0.032935486674217 | COAD | Male-baised eQTL |
| rs12766851 | chr10:90803074:C:T | - | -0.0475907590221719 | 0.035504216681818 | COAD | Male-baised eQTL |
| rs4933617 | chr10:90886965:G:T | - | -0.0443965690440068 | 0.038361121744753 | COAD | Male-baised eQTL |
| rs4272713 | chr10:90790215:A:G | - | -0.0476791234546086 | 0.0392242513296256 | COAD | Male-baised eQTL |
| rs35731058 | chr10:90789538:G:A | - | -0.0467348197734967 | 0.0457027704749573 | COAD | Male-baised eQTL |
| rs10786728 | chr10:102945949:C:G | - | 0.0637845803166043 | 0.0483485950277091 | COAD | Male-baised eQTL |
Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_52517 | chr10:95685555:95685636 | In-frame | rs10786273 | chr10:96249576:A:T | Distant upstream | 0.0731316866891473 | 0.00311025190010793 | HNSC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs1414918 | chr10:96054718:G:A | Distant upstream | 0.0285963533039899 | 0.0441646852826414 | LUSC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7099399 | chr10:96056663:G:A | Distant upstream | 0.028593673498164 | 0.0442349336793167 | LUSC | Female-baised sQTL |
| exon_skip_52517 | chr10:95685555:95685636 | In-frame | rs79227251 | chr10:95131449:G:A | Distant downstream | -0.051082554982288 | 0.0199928797052811 | COAD | Female-baised sQTL |
| exon_skip_52517 | chr10:95685555:95685636 | In-frame | rs74508836 | chr10:95233094:A:T | Distant downstream | -0.0509894637017844 | 0.0277190759509742 | COAD | Female-baised sQTL |
| exon_skip_52517 | chr10:95685555:95685636 | In-frame | rs80128313 | chr10:95128035:G:T | Distant downstream | -0.0502265689869159 | 0.0292522174497009 | COAD | Female-baised sQTL |
| exon_skip_52517 | chr10:95685555:95685636 | In-frame | rs113911362 | chr10:95130402:G:A | Distant downstream | -0.0502265689869159 | 0.0292522174497009 | COAD | Female-baised sQTL |
| exon_skip_52517 | chr10:95685555:95685636 | In-frame | rs76630128 | chr10:95103053:C:T | Distant downstream | -0.0485187195651846 | 0.0380807346955444 | COAD | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4917690 | chr10:95475234:C:A | Distant downstream | 0.025583505127038 | 0.0375038097681692 | STAD | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34519673 | chr10:96082576:T:C | Distant upstream | -0.0532099499701314 | 3.58970225092734e-06 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7096164 | chr10:96108448:G:T | Distant upstream | -0.051083620836498 | 4.61834554996223e-06 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34603628 | chr10:96111167:A:T | Distant upstream | -0.0509186169283973 | 5.06074550451703e-06 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs66728103 | chr10:96146577:C:G | Distant upstream | -0.0519854351605118 | 7.28931818379483e-06 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34091243 | chr10:96150153:T:C | Distant upstream | -0.0519854351605118 | 7.28931818379483e-06 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11591374 | chr10:96162820:A:G | Distant upstream | -0.0519854351605118 | 7.28931818379483e-06 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7916068 | chr10:96125232:C:A | Distant upstream | -0.0516518249608873 | 1.19924336498245e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs35038457 | chr10:96093249:G:A | Distant upstream | -0.0516444099769281 | 1.20492789184659e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34844027 | chr10:96172143:G:A | Distant upstream | -0.0516655799706575 | 1.29400177171564e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs141791178 | chr10:96184488:G:T | Distant upstream | -0.0516655799706575 | 1.29400177171564e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12764672 | chr10:96184661:T:C | Distant upstream | -0.0516655799706575 | 1.29400177171564e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11596126 | chr10:96058583:C:T | Distant upstream | -0.0523820237533176 | 1.89909867687921e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12778345 | chr10:96086310:C:T | Distant upstream | -0.0523820237533176 | 1.89909867687921e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11599662 | chr10:96074697:G:C | Distant upstream | -0.0523324826528219 | 2.09957698462508e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7081169 | chr10:96017418:A:C | Distant upstream | -0.0512304251823837 | 4.93837605479294e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34084924 | chr10:96018617:G:A | Distant upstream | -0.0512304251823837 | 4.93837605479294e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34660132 | chr10:96023865:A:G | Distant upstream | -0.0512304251823837 | 4.93837605479294e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs77477195 | chr10:96015480:C:T | Distant upstream | -0.0510184520576313 | 5.77866676417269e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs61869172 | chr10:96008758:T:C | Distant upstream | -0.0506889476272224 | 5.86671735365249e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12783483 | chr10:96009318:C:T | Distant upstream | -0.0506889476272224 | 5.86671735365249e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs61869173 | chr10:96010722:A:C | Distant upstream | -0.0506889476272224 | 5.86671735365249e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7918957 | chr10:96011235:T:C | Distant upstream | -0.0506889476272224 | 5.86671735365249e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs17383738 | chr10:96012601:A:G | Distant upstream | -0.0506889476272224 | 5.86671735365249e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs66719976 | chr10:96035908:G:A | Distant upstream | -0.0506732334461769 | 6.14741233707491e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs57334361 | chr10:96046151:A:G | Distant upstream | -0.0506732334461769 | 6.14741233707491e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12784299 | chr10:96048352:A:C | Distant upstream | -0.0506732334461769 | 6.14741233707491e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12768772 | chr10:96049545:T:A | Distant upstream | -0.0506732334461769 | 6.14741233707491e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34846723 | chr10:96049082:T:C | Distant upstream | -0.0505060578559964 | 7.0635165513745e-05 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12761346 | chr10:96215516:T:C | Distant upstream | -0.0547061610026109 | 0.000390504664980087 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs1053905 | chr10:95606607:C:T | Distant downstream | -0.0327782525380711 | 0.00080982168159561 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7099284 | chr10:95606989:C:T | Distant downstream | -0.0327782525380711 | 0.00080982168159561 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12778814 | chr10:95607360:G:T | Distant downstream | -0.0327782525380711 | 0.00080982168159561 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12780161 | chr10:95607442:T:C | Distant downstream | -0.0322711278958944 | 0.000984223490249871 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs58419111 | chr10:95607470:A:C | Distant downstream | -0.0322711278958944 | 0.000984223490249871 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7100377 | chr10:95607638:G:T | Distant downstream | -0.0322392998321166 | 0.00100638135312015 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188397 | chr10:95607754:C:A | Distant downstream | -0.0302705456528538 | 0.00286202104719011 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10786226 | chr10:95608046:C:T | Distant downstream | -0.0302705456528538 | 0.00286202104719011 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs61871788 | chr10:95613443:T:A | Distant downstream | -0.02905351143964 | 0.00846381691836493 | SARC | Female-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs543672 | chr10:95601959:C:G | Distant downstream | 0.0341212575745945 | 0.00905394926904069 | SARC | Female-baised sQTL |
Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4917702 | chr10:95704751:A:G | Distant upstream | -0.0193771357621049 | 0.00117142519937741 | HNSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4917703 | chr10:95705059:T:G | Distant upstream | -0.0193771357621049 | 0.00117142519937741 | HNSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882654 | chr10:95708832:G:T | Distant upstream | -0.0193771357621049 | 0.00117142519937741 | HNSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs3789928 | chr10:96243129:G:C | Distant upstream | 0.0191250971003883 | 0.00710106038116663 | HNSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs3789927 | chr10:96243110:G:T | Distant upstream | 0.0179515006109979 | 0.0194823357321442 | HNSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs35561941 | chr10:95412305:T:C | Distant downstream | -0.0471582492600424 | 0.001546477515705 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs41315245 | chr10:95413450:T:G | Distant downstream | -0.0470271629323367 | 0.00163404555650067 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34235944 | chr10:95409380:T:C | Distant downstream | -0.0470004260101768 | 0.00164651060049065 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12782272 | chr10:95418769:T:C | Distant downstream | -0.0452919835526561 | 0.00271539345203046 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12773574 | chr10:95414468:T:C | Distant downstream | -0.0450729123241719 | 0.00361461633978649 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7913557 | chr10:95459474:C:G | Distant downstream | 0.0211028979144328 | 0.00434187154157012 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7899065 | chr10:95459662:T:C | Distant downstream | 0.0211028979144328 | 0.00434187154157012 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4917690 | chr10:95475234:C:A | Distant downstream | 0.0203620539237097 | 0.00450719746037859 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34975945 | chr10:95424862:T:C | Distant downstream | -0.0393487728588196 | 0.00786529131211438 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs2027200 | chr10:95952362:C:A | Distant upstream | -0.0195059395511811 | 0.0117186612635123 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10219085 | chr10:95962752:T:C | Distant upstream | -0.0196412449563516 | 0.0119062584622467 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4369330 | chr10:95487859:A:G | Distant downstream | -0.0193569652235986 | 0.0144332850405919 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7893222 | chr10:95951352:A:G | Distant upstream | -0.0193480261795607 | 0.0149485747421274 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10736096 | chr10:95948096:C:G | Distant upstream | -0.0191859128980029 | 0.0164223328569699 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882697 | chr10:95948423:T:C | Distant upstream | -0.0191859128980029 | 0.0164223328569699 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs2039618 | chr10:95950905:T:C | Distant upstream | -0.0191859128980029 | 0.0164223328569699 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7893361 | chr10:95943962:G:A | Distant upstream | -0.0190967248339378 | 0.0182455851015816 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs35892931 | chr10:95405226:G:A | Distant downstream | -0.0378726098919308 | 0.0182950043981229 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs35265356 | chr10:95406855:C:G | Distant downstream | -0.0378726098919308 | 0.0182950043981229 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7074761 | chr10:95456173:A:G | Distant downstream | 0.0185621031689256 | 0.0195890492168965 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4918981 | chr10:95956539:T:A | Distant upstream | -0.0190159231590628 | 0.0196571427384969 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188537 | chr10:95947257:G:C | Distant upstream | -0.0189301025611825 | 0.0200413689433 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11593509 | chr10:95948495:G:A | Distant upstream | -0.0189301025611825 | 0.0200413689433 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs1110124 | chr10:95955302:G:T | Distant upstream | -0.0190844609951256 | 0.0203216373323105 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs1336458 | chr10:95960672:T:C | Distant upstream | -0.0188371460892555 | 0.0206051947211567 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs564370 | chr10:95466753:A:T | Distant downstream | 0.0178433740485854 | 0.0221771315070636 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs35480352 | chr10:95416169:C:T | Distant downstream | -0.0371336671598096 | 0.026675698220291 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs2148892 | chr10:95455754:T:G | Distant downstream | 0.0184378546942599 | 0.0273153887138818 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10786259 | chr10:96015810:G:A | Distant upstream | -0.0188475454956483 | 0.0294871301331121 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7904410 | chr10:95964490:G:A | Distant upstream | -0.018033125825939 | 0.0388565617596634 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7907620 | chr10:95964772:C:G | Distant upstream | -0.018033125825939 | 0.0388565617596634 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs6584044 | chr10:96007629:C:T | Distant upstream | -0.0174433689743291 | 0.040786078975474 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs2025851 | chr10:95380197:G:C | Distant downstream | 0.0175561773935353 | 0.0430698680512703 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7096743 | chr10:96008073:A:G | Distant upstream | -0.0172080511919477 | 0.0464976082791967 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7913835 | chr10:96009709:T:C | Distant upstream | -0.0172080511919477 | 0.0464976082791967 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4145209 | chr10:96010099:G:C | Distant upstream | -0.0172080511919477 | 0.0464976082791967 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs3748224 | chr10:96012496:C:T | Distant upstream | -0.0172080511919477 | 0.0464976082791967 | LUSC | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882628 | chr10:95570368:G:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188368 | chr10:95570705:C:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188370 | chr10:95571071:C:A | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188371 | chr10:95571075:C:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882629 | chr10:95571345:A:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882630 | chr10:95571349:G:A | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7086374 | chr10:95571440:A:C | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7099515 | chr10:95572096:G:C | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7099430 | chr10:95572201:C:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882631 | chr10:95572715:C:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882632 | chr10:95572786:C:T | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7896068 | chr10:95573655:A:G | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188376 | chr10:95581891:T:C | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs12218873 | chr10:95584280:G:C | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs73325195 | chr10:95585100:G:A | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882634 | chr10:95585965:A:C | Distant downstream | -0.0556959969673251 | 1.40978573274644e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188369 | chr10:95570771:A:C | Distant downstream | -0.0534192326322578 | 3.94240553994572e-05 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882633 | chr10:95585953:C:T | Distant downstream | -0.0492054461420428 | 0.000212845495549712 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7903143 | chr10:95587474:C:T | Distant downstream | -0.0492054461420428 | 0.000212845495549712 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs58020095 | chr10:95588613:A:C | Distant downstream | -0.0492054461420428 | 0.000212845495549712 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs10882635 | chr10:95589088:G:A | Distant downstream | -0.0492054461420428 | 0.000212845495549712 | COAD | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs34257762 | chr10:95444853:T:C | Distant downstream | -0.0648386159718242 | 0.000101706564174272 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4447105 | chr10:96482053:C:A | Distant upstream | -0.0252567327801944 | 0.00249552001792032 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7072595 | chr10:96489178:A:T | Distant upstream | -0.0249411770924129 | 0.003217458514125 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs2281800 | chr10:96480288:C:T | Distant upstream | -0.0244842128690745 | 0.00407230985539824 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs67832614 | chr10:95403545:C:T | Distant downstream | -0.0483435515567222 | 0.00498899223218775 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4589222 | chr10:96459847:G:A | Distant upstream | -0.0230447327283249 | 0.00519022384345924 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4347313 | chr10:96459924:A:G | Distant upstream | -0.0230447327283249 | 0.00519022384345924 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs57693102 | chr10:96483165:T:A | Distant upstream | -0.023752979552095 | 0.00566946376411024 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188783 | chr10:96478838:T:A | Distant upstream | -0.0233505171133964 | 0.00647293631179543 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188784 | chr10:96482700:A:G | Distant upstream | -0.0230103980928432 | 0.00663587708490219 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188766 | chr10:96458583:G:A | Distant upstream | -0.0227520368976164 | 0.00684530215033737 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs6584075 | chr10:96459383:C:T | Distant upstream | -0.0227520368976164 | 0.00684530215033737 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs35025323 | chr10:95330234:T:C | Distant downstream | -0.0365077386932467 | 0.0071363685957163 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7085635 | chr10:95327765:C:T | Distant downstream | -0.0364962497648937 | 0.00715360599781818 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs55904470 | chr10:96485832:C:T | Distant upstream | -0.0234934827489076 | 0.00724075923894182 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs55904429 | chr10:96485869:A:G | Distant upstream | -0.0230332142162201 | 0.0079185627755068 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7919971 | chr10:96486901:C:G | Distant upstream | -0.0230194660735914 | 0.00792781397516465 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs874370 | chr10:96486983:A:G | Distant upstream | -0.0230194660735914 | 0.00792781397516465 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs7923251 | chr10:96462818:G:C | Distant upstream | -0.0213134012462475 | 0.012959575154576 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs4917739 | chr10:96486504:G:A | Distant upstream | 0.0219613007415061 | 0.0130470041314608 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs874371 | chr10:96487265:T:C | Distant upstream | -0.0222159536268326 | 0.0144341489499384 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs243 | chr10:96480625:G:A | Distant upstream | 0.0211764340093032 | 0.0198126945412114 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs748109 | chr10:96481716:C:A | Distant upstream | 0.0211656033713555 | 0.020006293883238 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188790 | chr10:96489956:C:T | Distant upstream | -0.0221596882087597 | 0.0213867213364256 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs11188789 | chr10:96489834:C:T | Distant upstream | -0.0216874568284887 | 0.0296623382410575 | BLCA | Male-baised sQTL |
| exon_skip_52483 | chr10:95680471:95680609 | In-frame | rs61857635 | chr10:96488111:C:T | Distant upstream | -0.0209017525776344 | 0.0396792218727017 | BLCA | Male-baised sQTL |
Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of TCTN3 |
Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000119977 | TCTN3 | C0406727 | Orofaciodigital syndrome 4 | 1 | CTD_human |