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Gene: ENSG00000117868 |
Summary for ESYT2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000117868 | Gene symbol | ESYT2 |
| Gene name | extended synaptotagmin 2 | |
| HGNC | 22211 | |
| Entrez ID | 57488 | |
| Gene type | protein_coding | |
| Synonyms | ESYT2|KIAA1228|CHR2SYT | |
| UniProtAcc | A0FGR8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ESYT2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ESYT2 | 5.36e+03 | -1.04e+00 | 2.04e-01 | -5.11e+00 | 3.29e-07 | 2.88e-06 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for ESYT2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for ESYT2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
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Exon skipping events with PSI in TCGA for ESYT2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| CHOL | exon_skip_480913 | 5.85e-01 | 2.83e-01 | 2.88e+00 | 3.97e-03 | 1.32e-02 | 3.02e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_480913 | 6.71e-01 | 3.83e-01 | 1.24e+01 | 4.40e-35 | 4.02e-33 | 2.87e-01 |
| HNSC | exon_skip_480913 | 4.79e-01 | 6.14e-01 | -3.18e+00 | 1.47e-03 | 1.03e-02 | -1.36e-01 |
| STAD | exon_skip_480913 | 6.81e-01 | 5.53e-01 | 2.25e+00 | 2.42e-02 | 3.70e-02 | 1.28e-01 |
| LIHC | exon_skip_480913 | 4.91e-01 | 3.73e-01 | 3.03e+00 | 2.48e-03 | 7.46e-03 | 1.18e-01 |
| READ | exon_skip_480913 | 8.42e-01 | 7.13e-01 | 2.96e+00 | 3.09e-03 | 1.20e-02 | 1.28e-01 |
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RNA A-to-I editing events in TCGA for ESYT2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| KIRC | ESYT2-201 | chr7_158738265_- | 2.64e-01 | 1.95e-01 | 2.00e+00 | 4.57e-02 | 4.96e-02 | 6.98e-02 |
| LUAD | ESYT2-201 | chr7_158746124_- | 3.18e-01 | 4.52e-01 | -2.88e+00 | 3.95e-03 | 2.16e-02 | -1.34e-01 |
| LUAD | ESYT2-201 | chr7_158770914_- | 5.04e-01 | 3.49e-01 | 2.54e+00 | 1.10e-02 | 2.97e-02 | 1.55e-01 |
| COAD | ESYT2-201 | chr7_158738148_- | 3.11e-01 | 3.99e-01 | -2.11e+00 | 3.50e-02 | 4.26e-02 | -8.83e-02 |
| COAD | ESYT2-201 | chr7_158738200_- | 7.63e-01 | 4.90e-01 | 2.41e+00 | 1.59e-02 | 2.91e-02 | 2.74e-01 |
| COAD | ESYT2-201 | chr7_158738646_- | 7.06e-01 | 5.74e-01 | 2.00e+00 | 4.55e-02 | 4.80e-02 | 1.32e-01 |
| COAD | ESYT2-201 | chr7_158770914_- | 3.44e-01 | 3.60e-01 | -1.98e+00 | 4.79e-02 | 4.90e-02 | -1.55e-02 |
| COAD | ESYT2-201 | chr7_158789613_- | 2.68e-01 | 4.27e-01 | -3.27e+00 | 1.06e-03 | 1.45e-02 | -1.60e-01 |
| BLCA | ESYT2-201 | chr7_158738266_- | 3.18e-01 | 5.53e-01 | -2.33e+00 | 1.96e-02 | 4.98e-02 | -2.35e-01 |
| LAML | ESYT2-201 | chr7_158797316_- | 3.20e-01 | 4.67e-01 | -1.97e+00 | 4.87e-02 | 4.96e-02 | -1.47e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for ESYT2 |
| TFs related to ESYT2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LAML | ZNF418 | ESYT2 | 4.30e+00 | 9.84e-01 | 3.17e+00 | 4.19e-03 | Male-biased |
| PAAD | ZNF418 | ESYT2 | 4.42e+00 | 9.81e-01 | 3.60e+00 | 1.07e-02 | Male-biased |
| READ | FOXD2 | ESYT2 | 3.65e+00 | 1.09e-02 | 4.46e+00 | 9.81e-01 | Female-biased |
| READ | POU3F3 | ESYT2 | 3.67e+00 | 8.64e-03 | 4.54e+00 | 9.84e-01 | Female-biased |
| READ | ZNF334 | ESYT2 | 3.65e+00 | 3.64e-03 | 4.74e+00 | 9.92e-01 | Female-biased |
| READ | ZNF418 | ESYT2 | 3.79e+00 | 4.24e-03 | 4.84e+00 | 9.92e-01 | Female-biased |
| ESYT2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for ESYT2 |
| RBPs related to ES in ESYT2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | SAMD4A | exon_skip_480877 | 8.64e+00 | 9.92e-01 | 8.12e+00 | 2.48e-03 | Male-biased |
| ACC | SAMD4A | exon_skip_480877 | 9.04e+00 | 9.82e-01 | 8.65e+00 | 1.32e-02 | Male-biased |
| UVM | NOVA2 | exon_skip_480917 | 7.38e+00 | 9.84e-01 | 7.02e+00 | 4.24e-03 | Male-biased |
| UVM | RBM41 | exon_skip_480917 | 1.04e+01 | 9.96e-01 | 9.97e+00 | 2.24e-03 | Male-biased |
| UVM | ZC3H10 | exon_skip_480899 | 8.84e+00 | 1.47e-03 | 9.31e+00 | 9.95e-01 | Female-biased |
| LIHC | PABPC5 | exon_skip_480907 | 9.00e+00 | 2.71e-03 | 9.57e+00 | 9.95e-01 | Female-biased |
| LIHC | SAMD4A | exon_skip_480877 | 8.87e+00 | 9.81e-01 | 8.51e+00 | 1.41e-02 | Male-biased |
| LUSC | PABPC5 | exon_skip_480907 | 8.89e+00 | 5.07e-03 | 9.32e+00 | 9.92e-01 | Female-biased |
| BRCA | SAMD4A | exon_skip_480877 | 8.14e+00 | 1.93e-03 | 9.31e+00 | 9.95e-01 | Female-biased |
| ESCA | PABPC5 | exon_skip_480908 | 9.22e+00 | 9.83e-01 | 8.82e+00 | 1.36e-02 | Male-biased |
| READ | ZC3H10 | exon_skip_480899 | 9.27e+00 | 1.12e-02 | 9.59e+00 | 9.86e-01 | Female-biased |
| PCPG | FXR2 | exon_skip_480916 | 9.82e+00 | 9.94e-01 | 9.40e+00 | 3.49e-03 | Male-biased |
| PCPG | NOVA2 | exon_skip_480917 | 7.44e+00 | 9.82e-01 | 7.08e+00 | 6.71e-03 | Male-biased |
| PCPG | PABPC5 | exon_skip_480907 | 9.54e+00 | 9.87e-01 | 9.22e+00 | 1.01e-02 | Male-biased |
| PCPG | RBM41 | exon_skip_480917 | 1.00e+01 | 9.93e-01 | 9.65e+00 | 5.36e-03 | Male-biased |
| MESO | SAMD4A | exon_skip_480877 | 8.87e+00 | 9.82e-01 | 8.55e+00 | 1.34e-02 | Male-biased |
| LGG | SAMD4A | exon_skip_480928 | 8.67e+00 | 9.90e-01 | 8.26e+00 | 4.31e-03 | Male-biased |
| PAAD | RBM41 | exon_skip_480917 | 9.90e+00 | 9.95e-01 | 9.50e+00 | 2.71e-03 | Male-biased |
| KIRC | FXR2 | exon_skip_480916 | 9.89e+00 | 9.85e-01 | 9.60e+00 | 1.25e-02 | Male-biased |
| KIRC | PABPC5 | exon_skip_480907 | 9.38e+00 | 9.85e-01 | 9.09e+00 | 1.26e-02 | Male-biased |
| KIRC | SAMD4A | exon_skip_480877 | 8.58e+00 | 9.85e-01 | 8.27e+00 | 8.61e-03 | Male-biased |
| KICH | NOVA2 | exon_skip_480917 | 7.05e+00 | 3.52e-03 | 7.47e+00 | 9.86e-01 | Female-biased |
| KICH | RBM41 | exon_skip_480917 | 9.43e+00 | 1.29e-02 | 9.73e+00 | 9.85e-01 | Female-biased |
| BLCA | PABPC5 | exon_skip_480907 | 9.17e+00 | 9.00e-03 | 9.53e+00 | 9.88e-01 | Female-biased |
| SKCM | Fusip1 | exon_skip_480888 | 8.44e+00 | 3.63e-03 | 8.91e+00 | 9.92e-01 | Female-biased |
| SKCM | SAMD4A | exon_skip_480877 | 8.66e+00 | 9.84e-01 | 8.30e+00 | 9.92e-03 | Male-biased |
| HNSC | ZC3H10 | exon_skip_480899 | 9.77e+00 | 9.93e-01 | 9.36e+00 | 5.17e-03 | Male-biased |
| SARC | SAMD4A | exon_skip_480928 | 8.17e+00 | 8.42e-03 | 8.55e+00 | 9.85e-01 | Female-biased |
| ESYT2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000117868 | AC078785.1,hsa-mir-132,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AC105942.1,hsa-mir-152,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AC006213.2,hsa-mir-152,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AC078785.1,hsa-mir-212,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AC110597.1,hsa-mir-340,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AP000766.1,hsa-mir-340,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AC022364.1,hsa-mir-340,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AC073254.1,hsa-mir-340,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | LINC00683,hsa-mir-340,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | RASSF8-AS1,hsa-mir-340,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | AL450326.1,hsa-mir-372,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | PAXIP1-AS2,hsa-mir-582,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | RASSF8-AS1,hsa-mir-582,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000117868 | MEG8,hsa-mir-582,ESYT2 | Male-specific ceRNA | TCGA-BLCA |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12670573 | chr7:158791456:C:G | gene | 0.170603025500996 | 0.0138098058850825 | GBM | Female-baised eQTL |
| rs7802639 | chr7:158792373:A:C | gene | 0.170603025500996 | 0.0138098058850825 | GBM | Female-baised eQTL |
| rs11970932 | chr7:158794569:A:T | gene | 0.170603025500996 | 0.0138098058850825 | GBM | Female-baised eQTL |
| rs35296813 | chr7:158742082:C:T | gene | 0.191497001941366 | 0.0225281160878972 | GBM | Female-baised eQTL |
| rs58067542 | chr7:158800734:C:T | gene | 0.16570108553043 | 0.0261776527751426 | GBM | Female-baised eQTL |
| rs7784703 | chr7:158807900:T:C | gene | 0.166008347916539 | 0.0265975658520864 | GBM | Female-baised eQTL |
| rs59980573 | chr7:158741690:G:C | gene,CDS,exon | 0.182617241803476 | 0.0390002850801163 | GBM | Female-baised eQTL |
| rs28838990 | chr7:151938201:G:A | - | 0.155346706083548 | 0.0180967889441852 | LIHC | Female-baised eQTL |
| rs2538046 | chr7:151617076:G:A | - | 0.0490206499718432 | 0.00451523087969918 | LUAD | Female-baised eQTL |
| rs2727527 | chr7:151650376:A:C | - | 0.0462864255940654 | 0.0203031452078377 | LUAD | Female-baised eQTL |
| rs3807232 | chr7:154685607:G:A | - | -0.065968515032773 | 0.0324386577214784 | LUAD | Female-baised eQTL |
| rs11765730 | chr7:149396184:A:G | - | 0.0561246948551136 | 0.0372919774128953 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2305477 | chr7:158743697:A:C | gene,exon | 0.0720728199510752 | 0.00638783075052039 | KIRC | Male-baised eQTL |
| rs71547564 | chr7:158743717:T:C | gene,exon | 0.0720728199510752 | 0.00638783075052039 | KIRC | Male-baised eQTL |
| rs71547565 | chr7:158743720:T:C | gene,exon | 0.0720728199510752 | 0.00638783075052039 | KIRC | Male-baised eQTL |
| rs71547566 | chr7:158743731:C:G | gene,exon | 0.0720728199510752 | 0.00638783075052039 | KIRC | Male-baised eQTL |
| rs3816464 | chr7:158735887:C:G | gene | 0.0698157664907146 | 0.00831095210808256 | KIRC | Male-baised eQTL |
| rs35420830 | chr7:158742016:T:A | gene | 0.0690981783562472 | 0.00939607178125842 | KIRC | Male-baised eQTL |
| rs9638138 | chr7:158744553:T:C | gene | 0.0684493496713958 | 0.0108600776360887 | KIRC | Male-baised eQTL |
| rs35215816 | chr7:158742131:T:C | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs35535423 | chr7:158742160:A:G | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs3750053 | chr7:158742423:C:G | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs3750055 | chr7:158742596:C:G | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs13227227 | chr7:158742987:T:C | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs2305473 | chr7:158743576:T:C | gene,CDS,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs2305475 | chr7:158743654:A:G | gene,CDS,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs2305476 | chr7:158743685:A:C | gene,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs61362305 | chr7:158743738:A:G | gene,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs66795622 | chr7:158743774:T:G | gene,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs71547567 | chr7:158743902:A:G | gene,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs71547568 | chr7:158743911:A:G | gene,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs66478815 | chr7:158743935:A:G | gene,exon | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs9638136 | chr7:158744251:C:T | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs9638139 | chr7:158744579:T:G | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs9638140 | chr7:158744857:C:T | gene | 0.0678186258104197 | 0.0121772462956022 | KIRC | Male-baised eQTL |
| rs3816462 | chr7:158735542:A:G | gene,CDS,exon | 0.068195581296488 | 0.0124181530936819 | KIRC | Male-baised eQTL |
| rs59080622 | chr7:158740831:A:G | gene | 0.0672229008131014 | 0.0137124346178685 | KIRC | Male-baised eQTL |
| rs7803766 | chr7:158738950:G:A | gene | 0.0671025169796857 | 0.0141929234213251 | KIRC | Male-baised eQTL |
| rs35073742 | chr7:158736106:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs34925038 | chr7:158736128:C:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs73729965 | chr7:158736180:C:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6942535 | chr7:158736386:A:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6960146 | chr7:158736572:G:A | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6961811 | chr7:158736869:C:T | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6960873 | chr7:158737013:G:A | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs2305467 | chr7:158737198:T:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs2305468 | chr7:158737441:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6952575 | chr7:158737747:T:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6965969 | chr7:158737881:G:A | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6967103 | chr7:158737941:C:A | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6967235 | chr7:158737974:C:T | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6948931 | chr7:158738070:A:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs6967423 | chr7:158738142:C:T | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs13228376 | chr7:158738238:A:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs67740724 | chr7:158738395:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs34249621 | chr7:158738566:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs34027025 | chr7:158738614:G:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs58784790 | chr7:158738809:G:A | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs7780879 | chr7:158739197:G:A | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs7800556 | chr7:158739202:A:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs7804422 | chr7:158739316:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs7804548 | chr7:158739363:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs13242285 | chr7:158739536:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs67791668 | chr7:158739763:T:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs56030281 | chr7:158740079:G:C | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs35308598 | chr7:158740311:A:G | gene | 0.0669346049886667 | 0.014406881641843 | KIRC | Male-baised eQTL |
| rs60721428 | chr7:158741001:G:A | gene | 0.0671437373182281 | 0.014988276231801 | KIRC | Male-baised eQTL |
| rs55933756 | chr7:158741002:T:C | gene | 0.0671437373182281 | 0.014988276231801 | KIRC | Male-baised eQTL |
| rs3750054 | chr7:158742506:G:A | gene | 0.0666593044934503 | 0.0154001257214103 | KIRC | Male-baised eQTL |
| rs3816465 | chr7:158735911:A:G | gene | -0.0627701090708022 | 0.0154101677153505 | KIRC | Male-baised eQTL |
| rs6960190 | chr7:158736658:G:T | gene | 0.0663609486503872 | 0.0163863343859477 | KIRC | Male-baised eQTL |
| rs59345485 | chr7:158740121:G:C | gene | 0.0663759618212033 | 0.016465949777677 | KIRC | Male-baised eQTL |
| rs62478929 | chr7:158740613:T:C | gene | 0.0656095473129297 | 0.0168964746277824 | KIRC | Male-baised eQTL |
| rs2788469 | chr7:158748572:C:T | gene | -0.0625159866759616 | 0.0181530329088979 | KIRC | Male-baised eQTL |
| rs2602542 | chr7:158767930:A:C | gene | -0.0609749363152379 | 0.0200460739911237 | KIRC | Male-baised eQTL |
| rs1470869 | chr7:158740207:G:A | gene | -0.0614808281755429 | 0.0209450866492492 | KIRC | Male-baised eQTL |
| rs34277519 | chr7:158741294:A:C | gene | 0.0650542458773779 | 0.0213435294278163 | KIRC | Male-baised eQTL |
| rs1189200 | chr7:158768791:G:A | gene | -0.0606533907790829 | 0.0216961717648703 | KIRC | Male-baised eQTL |
| rs34175774 | chr7:158741100:G:C | gene | 0.0649874604924993 | 0.022137106838649 | KIRC | Male-baised eQTL |
| rs34002332 | chr7:158741111:A:G | gene | 0.0649874604924993 | 0.022137106838649 | KIRC | Male-baised eQTL |
| rs35242235 | chr7:158738621:G:T | gene | 0.0644786799671366 | 0.023929447240525 | KIRC | Male-baised eQTL |
| rs6942868 | chr7:158736648:A:G | gene | 0.0646437149397526 | 0.0240643818373382 | KIRC | Male-baised eQTL |
| rs1189198 | chr7:158768605:G:C | gene | -0.0597537986778119 | 0.0262184655693498 | KIRC | Male-baised eQTL |
| rs13242353 | chr7:158726423:G:T | - | 0.0645172265671405 | 0.0308986963096051 | KIRC | Male-baised eQTL |
| rs62478935 | chr7:158746034:T:C | gene | 0.0625972879304621 | 0.0324370349145148 | KIRC | Male-baised eQTL |
| rs2305471 | chr7:158743439:T:C | gene | 0.0620050529593972 | 0.0334083133403922 | KIRC | Male-baised eQTL |
| rs2305472 | chr7:158743463:A:G | gene | 0.0620050529593972 | 0.0334083133403922 | KIRC | Male-baised eQTL |
| rs62478934 | chr7:158744017:T:C | gene,exon | 0.063732250509163 | 0.0335077696158659 | KIRC | Male-baised eQTL |
| rs842437 | chr7:158762758:C:T | gene | -0.0581404398786771 | 0.0343585252914255 | KIRC | Male-baised eQTL |
| rs896859 | chr7:158759640:C:G | gene | -0.0580227643158572 | 0.0348651377830061 | KIRC | Male-baised eQTL |
| rs35789103 | chr7:158757764:T:G | gene | -0.0578459154884173 | 0.0364743476407247 | KIRC | Male-baised eQTL |
| rs13242618 | chr7:158731905:C:T | gene,exon,UTR | 0.0613947393783568 | 0.0372863791441266 | KIRC | Male-baised eQTL |
| rs35109208 | chr7:158731908:T:C | gene,exon,UTR | 0.0613947393783568 | 0.0372863791441266 | KIRC | Male-baised eQTL |
| rs842450 | chr7:158774732:C:A | gene | -0.0567136306384398 | 0.0392695427941177 | KIRC | Male-baised eQTL |
| rs1098898 | chr7:158777041:T:A | gene | -0.0567136306384398 | 0.0392695427941177 | KIRC | Male-baised eQTL |
| rs13229349 | chr7:158731839:A:G | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs13232511 | chr7:158731960:T:C | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs3763406 | chr7:158732072:A:G | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs3763411 | chr7:158732374:T:G | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs3763412 | chr7:158732395:C:T | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs1061620 | chr7:158732475:G:A | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs1061739 | chr7:158733663:G:A | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs1061735 | chr7:158733764:G:T | gene,exon,UTR | 0.0608720405619528 | 0.0399857633867147 | KIRC | Male-baised eQTL |
| rs2383401 | chr7:158770521:A:T | gene | 0.0605634616857417 | 0.0400008062779811 | KIRC | Male-baised eQTL |
| rs4256546 | chr7:158745814:G:C | gene | 0.061537841178249 | 0.0413710057868946 | KIRC | Male-baised eQTL |
| rs2013 | chr7:158731197:T:C | gene,exon,UTR | 0.0602989214664223 | 0.0423733356576285 | KIRC | Male-baised eQTL |
| rs842452 | chr7:158782749:T:G | gene | -0.0563044707949987 | 0.0426644133743218 | KIRC | Male-baised eQTL |
| rs34119683 | chr7:158733200:G:C | gene,exon,UTR | 0.0608199280010123 | 0.0455107032754093 | KIRC | Male-baised eQTL |
| rs3750052 | chr7:158734360:T:C | gene | 0.0601388142950562 | 0.0467922841494976 | KIRC | Male-baised eQTL |
| rs842443 | chr7:158777801:C:T | gene | -0.0554854858989811 | 0.0486828646253765 | KIRC | Male-baised eQTL |
| rs746825 | chr7:158818315:A:C | gene | -0.0574930685901971 | 0.0488602339388728 | KIRC | Male-baised eQTL |
| rs1189218 | chr7:158821089:A:C | gene | -0.0574815495808105 | 0.0493484486361659 | KIRC | Male-baised eQTL |
| rs1154003 | chr7:158824194:G:A | gene | -0.0574815495808105 | 0.0493484486361659 | KIRC | Male-baised eQTL |
| rs3110887 | chr7:153508405:T:G | - | -0.0711050451414464 | 0.00542523236704098 | COAD | Male-baised eQTL |
| rs6464269 | chr7:152684170:G:C | - | 0.0612020085705462 | 0.00986980170381507 | COAD | Male-baised eQTL |
| rs4727094 | chr7:149646257:C:T | - | 0.103580412690869 | 0.0154598841151941 | COAD | Male-baised eQTL |
| rs12534900 | chr7:155390106:C:T | - | 0.0980328954961353 | 0.017083001310823 | COAD | Male-baised eQTL |
| rs3793177 | chr7:158647583:T:C | - | -0.0613220986995625 | 0.0172014032761497 | COAD | Male-baised eQTL |
| rs926102 | chr7:153065831:G:A | - | -0.0700155219221716 | 0.0179057160685969 | COAD | Male-baised eQTL |
| rs39170 | chr7:153966537:G:A | - | -0.0741124040268492 | 0.031708736587106 | COAD | Male-baised eQTL |
| rs6968313 | chr7:153057032:G:C | - | -0.0683364424818201 | 0.0320418645114963 | COAD | Male-baised eQTL |
| rs6951736 | chr7:153382341:C:A | - | 0.0696343601679658 | 0.036887731826221 | COAD | Male-baised eQTL |
| rs2886777 | chr7:157812116:T:C | - | 0.115036971479195 | 0.0399589595274673 | COAD | Male-baised eQTL |
| rs10264451 | chr7:155928651:T:C | - | -0.0865174729536241 | 0.0422226975590443 | COAD | Male-baised eQTL |
| rs11764861 | chr7:155928776:G:C | - | -0.0865174729536241 | 0.0422226975590443 | COAD | Male-baised eQTL |
| rs149626279 | chr7:158034198:C:T | - | 0.117672908298714 | 0.0436748377614372 | COAD | Male-baised eQTL |
| rs7790529 | chr7:155928851:T:A | - | -0.0861472339032773 | 0.0439515339116789 | COAD | Male-baised eQTL |
| rs380117 | chr7:159182924:T:C | - | 0.0549105609231853 | 0.049030025555802 | COAD | Male-baised eQTL |
| rs4716632 | chr7:156549504:C:G | - | -0.0556387561005006 | 0.0494518337521713 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000117868 |
| CpG Site: cg06111140 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.112069904035244 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg06111140 | chr7:158783065 | gene | -0.112069904035244 | 5.80711102961522e-05 | -0.3226961699495041 | 1.3689393761259802e-07 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of ESYT2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
