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Gene: ENSG00000116990 |
Summary for MYCL |
Gene summary |
| Gene information | Ensembl ID | ENSG00000116990 | Gene symbol | MYCL |
| Gene name | MYCL proto-oncogene, bHLH transcription factor | |
| HGNC | 7555 | |
| Entrez ID | 4610 | |
| Gene type | protein_coding | |
| Synonyms | MYCL|LMYC|bHLHe38 | |
| UniProtAcc | P12524 |
Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for MYCL |
AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
Landscape of gene expressions across multiple cancer types. |
Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| MYCL | 7.60e+02 | 1.07e+00 | 2.86e-01 | 3.73e+00 | 1.92e-04 | 4.70e-04 | LUAD |
| MYCL | 6.98e+03 | 1.64e+00 | 5.41e-01 | 3.04e+00 | 2.37e-03 | 6.96e-03 | BLCA |
| MYCL | 5.15e+02 | -1.64e+00 | 4.57e-01 | -3.59e+00 | 3.37e-04 | 1.30e-03 | CHOL |
Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for MYCL |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for MYCL |
Landscape of DNA methylation across multiple cancer types. |
Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
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Exon skipping events with PSI in TCGA for MYCL |
| ∗Please access ExonSkipDB for exon skipping annotation. |
Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for MYCL |
| ∗Please access CAeditome for RNA editing annotation. |
Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for MYCL |
TFs related to MYCL.∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ESCA | HINFP | MYCL | 4.36e+00 | 9.82e-01 | 3.65e+00 | 1.09e-02 | Male-biased |
| ESCA | KLF9 | MYCL | 3.83e+00 | 9.80e-01 | 2.92e+00 | 3.21e-03 | Male-biased |
| ESCA | TCFL5 | MYCL | 4.50e+00 | 9.91e-01 | 3.61e+00 | 3.71e-03 | Male-biased |
| ESCA | ZFP64 | MYCL | 3.98e+00 | 9.84e-01 | 3.07e+00 | 3.26e-03 | Male-biased |
| ESCA | ZNF100 | MYCL | 4.16e+00 | 9.89e-01 | 3.08e+00 | 1.24e-03 | Male-biased |
| ESCA | ZNF141 | MYCL | 4.25e+00 | 9.88e-01 | 3.36e+00 | 3.74e-03 | Male-biased |
| ESCA | ZNF2 | MYCL | 4.46e+00 | 9.90e-01 | 3.59e+00 | 4.18e-03 | Male-biased |
| ESCA | ZNF267 | MYCL | 3.97e+00 | 9.83e-01 | 3.09e+00 | 3.84e-03 | Male-biased |
| ESCA | ZNF30 | MYCL | 3.95e+00 | 9.85e-01 | 2.94e+00 | 1.88e-03 | Male-biased |
| ESCA | ZNF311 | MYCL | 4.13e+00 | 9.89e-01 | 3.06e+00 | 1.32e-03 | Male-biased |
| ESCA | ZNF44 | MYCL | 3.99e+00 | 9.83e-01 | 3.11e+00 | 3.97e-03 | Male-biased |
| ESCA | ZNF460 | MYCL | 4.27e+00 | 9.84e-01 | 3.50e+00 | 7.63e-03 | Male-biased |
| ESCA | ZNF611 | MYCL | 4.30e+00 | 9.92e-01 | 3.14e+00 | 8.40e-04 | Male-biased |
| ESCA | ZNF740 | MYCL | 4.19e+00 | 9.81e-01 | 3.46e+00 | 9.71e-03 | Male-biased |
| ESCA | ZNF792 | MYCL | 4.05e+00 | 9.87e-01 | 3.00e+00 | 1.45e-03 | Male-biased |
| ESCA | ZSCAN22 | MYCL | 4.05e+00 | 9.80e-01 | 3.31e+00 | 8.63e-03 | Male-biased |
| MESO | ZFP82 | MYCL | 3.24e+00 | 8.26e-03 | 4.58e+00 | 9.85e-01 | Female-biased |
| MESO | ZNF418 | MYCL | 2.43e+00 | 6.23e-05 | 5.03e+00 | 9.97e-01 | Female-biased |
| UVM | PLAG1 | MYCL | 4.70e+00 | 9.82e-01 | 3.19e+00 | 6.51e-03 | Male-biased |
| UVM | ZNF141 | MYCL | 4.76e+00 | 9.82e-01 | 3.30e+00 | 7.24e-03 | Male-biased |
| UVM | ZNF331 | MYCL | 5.00e+00 | 9.85e-01 | 3.49e+00 | 6.78e-03 | Male-biased |
| UVM | ZNF530 | MYCL | 4.65e+00 | 9.81e-01 | 3.15e+00 | 6.65e-03 | Male-biased |
| UVM | ZNF682 | MYCL | 4.70e+00 | 9.80e-01 | 3.27e+00 | 7.70e-03 | Male-biased |
| UVM | ZNF692 | MYCL | 4.91e+00 | 9.85e-01 | 3.39e+00 | 6.48e-03 | Male-biased |
MYCL related gene.∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for MYCL |
RBPs related to ES in MYCL.∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
MYCL related ES.∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000116990 | AC010615.2,hsa-mir-212,MYCL | Male-specific ceRNA | TCGA-BLCA |
Top |
Sex-biased eQTL regulation of gene |
Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2889739 | chr1:39523036:A:G | - | 0.13548685544011 | 0.000166687063436062 | LUSC | Female-baised eQTL |
| rs77853107 | chr1:39128327:T:C | - | 0.128398975238321 | 0.000173860670118047 | LUSC | Female-baised eQTL |
| rs60767579 | chr1:38051797:C:T | - | 0.128403856002277 | 0.000731658224921064 | LUSC | Female-baised eQTL |
| rs61186346 | chr1:38057373:G:T | - | 0.128403856002277 | 0.000731658224921064 | LUSC | Female-baised eQTL |
| rs508546 | chr1:33663877:C:T | - | -0.124206897826022 | 0.001295600883846 | LUSC | Female-baised eQTL |
| rs17449603 | chr1:46768061:A:G | - | 0.118324770070853 | 0.00164338160502185 | LUSC | Female-baised eQTL |
| rs11205918 | chr1:38068193:C:T | - | 0.120659427350282 | 0.00185980734430859 | LUSC | Female-baised eQTL |
| rs557147 | chr1:38080528:G:A | - | 0.12060847644793 | 0.001918353791245 | LUSC | Female-baised eQTL |
| rs12131530 | chr1:38080626:C:G | - | 0.12060847644793 | 0.001918353791245 | LUSC | Female-baised eQTL |
| rs474975 | chr1:38081267:A:C | - | 0.12060847644793 | 0.001918353791245 | LUSC | Female-baised eQTL |
| rs550582 | chr1:38081582:T:C | - | 0.12060847644793 | 0.001918353791245 | LUSC | Female-baised eQTL |
| rs534782 | chr1:38083175:G:A | - | 0.12060847644793 | 0.001918353791245 | LUSC | Female-baised eQTL |
| rs72918865 | chr1:38083627:T:C | - | 0.12060847644793 | 0.001918353791245 | LUSC | Female-baised eQTL |
| rs477471 | chr1:38087754:T:C | - | 0.120586711026657 | 0.00193735252565022 | LUSC | Female-baised eQTL |
| rs1690553 | chr1:33643600:T:G | - | 0.115988617271569 | 0.00255345796165204 | LUSC | Female-baised eQTL |
| rs514427 | chr1:33636872:A:G | - | 0.115940346152044 | 0.00257938776453269 | LUSC | Female-baised eQTL |
| rs72662047 | chr1:33641043:C:T | - | 0.115940346152044 | 0.00257938776453269 | LUSC | Female-baised eQTL |
| rs597802 | chr1:33632393:T:C | - | 0.109963102336458 | 0.0046998191601605 | LUSC | Female-baised eQTL |
| rs677357 | chr1:33632662:T:C | - | 0.109963102336458 | 0.0046998191601605 | LUSC | Female-baised eQTL |
| rs603854 | chr1:33633130:T:C | - | 0.109963102336458 | 0.0046998191601605 | LUSC | Female-baised eQTL |
| rs472484 | chr1:33633157:A:G | - | 0.109963102336458 | 0.0046998191601605 | LUSC | Female-baised eQTL |
| rs651972 | chr1:33631155:G:A | - | 0.109934722495092 | 0.00475344052388814 | LUSC | Female-baised eQTL |
| rs510533 | chr1:33648074:G:A | - | 0.109278504584259 | 0.00525119282094624 | LUSC | Female-baised eQTL |
| rs640394 | chr1:33648892:G:A | - | 0.109278504584259 | 0.00525119282094624 | LUSC | Female-baised eQTL |
| rs590210 | chr1:33649668:T:C | - | 0.109324058676779 | 0.00529239599119659 | LUSC | Female-baised eQTL |
| rs653470 | chr1:33647945:A:G | - | 0.109194978388729 | 0.00537931583272904 | LUSC | Female-baised eQTL |
| rs12121956 | chr1:38053013:T:C | - | 0.107754818917196 | 0.00557114596997107 | LUSC | Female-baised eQTL |
| rs513593 | chr1:33667254:C:G | - | -0.110140184464531 | 0.0056926826703807 | LUSC | Female-baised eQTL |
| rs617090 | chr1:33671866:C:G | - | -0.110140184464531 | 0.0056926826703807 | LUSC | Female-baised eQTL |
| rs6656365 | chr1:33674400:G:A | - | -0.110140184464531 | 0.0056926826703807 | LUSC | Female-baised eQTL |
| rs138051876 | chr1:33675755:G:C | - | -0.110140184464531 | 0.0056926826703807 | LUSC | Female-baised eQTL |
| rs532377 | chr1:33664184:A:T | - | -0.110266228605843 | 0.00576360490743191 | LUSC | Female-baised eQTL |
| rs642676 | chr1:33664541:C:T | - | -0.110266228605843 | 0.00576360490743191 | LUSC | Female-baised eQTL |
| rs629139 | chr1:33671512:A:T | - | -0.110038234508185 | 0.00583686632685138 | LUSC | Female-baised eQTL |
| rs2480244 | chr1:33687594:C:T | - | -0.110055216721549 | 0.00595713052057456 | LUSC | Female-baised eQTL |
| rs617364 | chr1:33688415:G:A | - | -0.110055216721549 | 0.00595713052057456 | LUSC | Female-baised eQTL |
| rs11210273 | chr1:41482073:G:A | - | 0.110642916748222 | 0.00722559421026315 | LUSC | Female-baised eQTL |
| rs906229 | chr1:36723370:C:T | - | 0.101154398227556 | 0.00854592408304638 | LUSC | Female-baised eQTL |
| rs644477 | chr1:33670674:A:T | - | -0.104898530827729 | 0.00927626616143839 | LUSC | Female-baised eQTL |
| rs12758772 | chr1:34465856:G:A | - | 0.101687016148864 | 0.0102777046958496 | LUSC | Female-baised eQTL |
| rs477882 | chr1:38081625:G:A | - | 0.102478705184928 | 0.012327706388364 | LUSC | Female-baised eQTL |
| rs67093630 | chr1:42090011:T:G | - | 0.100745454520437 | 0.0156447887723977 | LUSC | Female-baised eQTL |
| rs72658212 | chr1:33303648:C:T | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs117311352 | chr1:33309362:C:G | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs149592187 | chr1:33310176:G:A | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs72658217 | chr1:33311542:T:C | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs56111574 | chr1:33313939:A:C | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs77898537 | chr1:33314213:C:T | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs72658222 | chr1:33315771:A:C | - | 0.0931323483351901 | 0.0179714115060573 | LUSC | Female-baised eQTL |
| rs625757 | chr1:33684285:G:A | - | -0.0985011019884924 | 0.0194187480419693 | LUSC | Female-baised eQTL |
| rs512527 | chr1:33683153:G:A | - | -0.0984401396921726 | 0.0197647897858741 | LUSC | Female-baised eQTL |
| rs785105 | chr1:39731198:T:C | - | 0.0846319195351652 | 0.0201743612113802 | LUSC | Female-baised eQTL |
| rs11590973 | chr1:41460981:C:T | - | 0.0959088376060641 | 0.0204750788920453 | LUSC | Female-baised eQTL |
| rs60873474 | chr1:41461119:G:A | - | 0.0959088376060641 | 0.0204750788920453 | LUSC | Female-baised eQTL |
| rs57590210 | chr1:42107951:C:T | - | 0.0956587968249252 | 0.0240213544232528 | LUSC | Female-baised eQTL |
| rs74836434 | chr1:42108511:A:T | - | 0.0956587968249252 | 0.0240213544232528 | LUSC | Female-baised eQTL |
| rs58217148 | chr1:42096163:A:G | - | 0.0956630379583873 | 0.0241337029432618 | LUSC | Female-baised eQTL |
| rs72953293 | chr1:42090222:C:G | - | 0.0956250473214643 | 0.0244314671695756 | LUSC | Female-baised eQTL |
| rs61779334 | chr1:39517350:C:G | - | 0.0847843691322302 | 0.0246512057644799 | LUSC | Female-baised eQTL |
| rs12142615 | chr1:41473424:T:C | - | 0.0981256240560413 | 0.0249386163599539 | LUSC | Female-baised eQTL |
| rs12143601 | chr1:41474351:T:C | - | 0.0981256240560413 | 0.0249386163599539 | LUSC | Female-baised eQTL |
| rs529714 | chr1:33671848:C:T | - | -0.0944921960715813 | 0.025389663753916 | LUSC | Female-baised eQTL |
| rs16835356 | chr1:33323042:C:T | - | 0.0892180884661696 | 0.0264639086830646 | LUSC | Female-baised eQTL |
| rs72658229 | chr1:33323329:G:A | - | 0.0892180884661696 | 0.0264639086830646 | LUSC | Female-baised eQTL |
| rs72658232 | chr1:33323376:G:C | - | 0.0892180884661696 | 0.0264639086830646 | LUSC | Female-baised eQTL |
| rs72658237 | chr1:33328815:T:C | - | 0.0892180884661696 | 0.0264639086830646 | LUSC | Female-baised eQTL |
| rs16835363 | chr1:33329452:C:T | - | 0.0892180884661696 | 0.0264639086830646 | LUSC | Female-baised eQTL |
| rs41265891 | chr1:33331290:C:A | - | 0.0892180884661696 | 0.0264639086830646 | LUSC | Female-baised eQTL |
| rs16835424 | chr1:33391506:C:T | - | 0.0806187462744301 | 0.0282056158747538 | LUSC | Female-baised eQTL |
| rs72658260 | chr1:33357993:G:C | - | 0.0884978091191193 | 0.0299847522120432 | LUSC | Female-baised eQTL |
| rs11206277 | chr1:39535654:G:A | - | 0.085459927908223 | 0.0323316416389645 | LUSC | Female-baised eQTL |
| rs71654257 | chr1:42754456:G:T | - | 0.0925200077680177 | 0.0348163525696215 | LUSC | Female-baised eQTL |
| rs3738502 | chr1:42755516:C:T | - | 0.0925200077680177 | 0.0348163525696215 | LUSC | Female-baised eQTL |
| rs3738503 | chr1:42757636:C:T | - | 0.0925200077680177 | 0.0348163525696215 | LUSC | Female-baised eQTL |
| rs11585208 | chr1:42756768:C:T | - | 0.0924823057683042 | 0.0352432461182067 | LUSC | Female-baised eQTL |
| rs12744838 | chr1:42763388:G:A | - | 0.0924823057683042 | 0.0352432461182067 | LUSC | Female-baised eQTL |
| rs11210267 | chr1:41480960:A:G | - | 0.0937562211090637 | 0.0363887459265976 | LUSC | Female-baised eQTL |
| rs11210269 | chr1:41481664:G:A | - | 0.0937562211090637 | 0.0363887459265976 | LUSC | Female-baised eQTL |
| rs12566493 | chr1:33343395:T:C | - | 0.0856420307159397 | 0.0377716704354123 | LUSC | Female-baised eQTL |
| rs7534135 | chr1:33422769:C:T | - | 0.0857011508891978 | 0.038202397634615 | LUSC | Female-baised eQTL |
| rs55860530 | chr1:33434058:C:T | - | 0.0856823649386216 | 0.0383348058475309 | LUSC | Female-baised eQTL |
| rs72660106 | chr1:33423112:T:G | - | 0.0857012216756102 | 0.0386654458725161 | LUSC | Female-baised eQTL |
| rs10493053 | chr1:33423207:T:C | - | 0.0856925159168425 | 0.0387233253907799 | LUSC | Female-baised eQTL |
| rs55798146 | chr1:33429048:T:C | - | 0.0856822582414892 | 0.0387710184382381 | LUSC | Female-baised eQTL |
| rs16835467 | chr1:33426737:T:C | - | 0.0856371270215928 | 0.0390414013999821 | LUSC | Female-baised eQTL |
| rs72660114 | chr1:33427582:C:A | - | 0.0856371270215928 | 0.0390414013999821 | LUSC | Female-baised eQTL |
| rs11210560 | chr1:41994779:A:T | - | 0.0868543741591709 | 0.0390542158765438 | LUSC | Female-baised eQTL |
| rs72668106 | chr1:36739904:G:T | - | 0.084217346906075 | 0.0391406344433521 | LUSC | Female-baised eQTL |
| rs11210199 | chr1:41460577:C:T | - | 0.0878254881896384 | 0.0416120445577097 | LUSC | Female-baised eQTL |
| rs11584399 | chr1:39523340:G:A | - | 0.0786913736872824 | 0.0473002952599221 | LUSC | Female-baised eQTL |
| rs4078261 | chr1:36515022:A:T | - | 0.070137700034792 | 0.0473393820446251 | LUSC | Female-baised eQTL |
Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11209130 | chr1:38224439:A:G | - | 0.0340357174487274 | 0.035882299090113 | LUSC | Male-baised eQTL |
| rs10915084 | chr1:30338004:T:C | - | -0.0271932489648148 | 0.0367958680017131 | LUSC | Male-baised eQTL |
| rs11209146 | chr1:38225806:C:G | - | 0.0330859019053436 | 0.0402480223839048 | LUSC | Male-baised eQTL |
| rs12077373 | chr1:30343521:A:C | - | -0.0264636099307707 | 0.0411977972673396 | LUSC | Male-baised eQTL |
| rs4949256 | chr1:30337303:C:T | - | -0.0268397963706426 | 0.041632844765468 | LUSC | Male-baised eQTL |
| rs12071443 | chr1:30343611:G:A | - | -0.0263752544019336 | 0.0427488740417987 | LUSC | Male-baised eQTL |
| rs12758361 | chr1:46869185:G:A | - | 0.0625257899668718 | 0.0285592741959916 | STAD | Male-baised eQTL |
| rs12404046 | chr1:30727031:A:T | - | 0.0544059956440661 | 0.0396294963989854 | BLCA | Male-baised eQTL |
| rs6600282 | chr1:38963262:G:C | - | -0.0668947982958134 | 5.22902367977688e-05 | LUAD | Male-baised eQTL |
| rs9662216 | chr1:38952689:G:A | - | -0.0550122555472544 | 0.00127354080479877 | LUAD | Male-baised eQTL |
| rs57213592 | chr1:38956702:A:G | - | -0.0550122555472544 | 0.00127354080479877 | LUAD | Male-baised eQTL |
| rs4475740 | chr1:38959817:A:G | - | -0.0505634400848295 | 0.00239088571297383 | LUAD | Male-baised eQTL |
Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Gene ID: ENSG00000116990 | |
| CpG Site: cg16163765 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: -0.490797684551961 | |
| Female Effect: - |
Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg16163765 | chr1:39899827 | gene,exon,UTR | -0.490797684551961 | 3.70319983739905e-64 | -0.8676227884330778 | 1.0777731164064074e-68 | LUAD |
Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of MYCL |
Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000116990 | MYCL | C0025149 | Medulloblastoma | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0205833 | Medullomyoblastoma | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0278510 | Childhood Medulloblastoma | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0278876 | Adult Medulloblastoma | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| ENSG00000116990 | MYCL | C0751291 | Desmoplastic Medulloblastoma | 1 | CTD_human |
| ENSG00000116990 | MYCL | C1275668 | Melanotic medulloblastoma | 1 | CTD_human |