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Gene: ENSG00000115380 |
Summary for EFEMP1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000115380 | Gene symbol | EFEMP1 |
| Gene name | EGF containing fibulin extracellular matrix protein 1 | |
| HGNC | 3218 | |
| Entrez ID | 2202 | |
| Gene type | protein_coding | |
| Synonyms | EFEMP1|S1-5|FBLN3|MTLV | |
| UniProtAcc | Q12805 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for EFEMP1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EFEMP1 | 2.04e+03 | -1.47e+00 | 2.47e-01 | -5.97e+00 | 2.36e-09 | 1.20e-07 | KIRP |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EFEMP1 | 2.76e+03 | -2.06e+00 | 6.80e-01 | -3.03e+00 | 2.46e-03 | 7.19e-03 | BLCA |
| EFEMP1 | 1.70e+03 | -1.85e+00 | 3.75e-01 | -4.93e+00 | 8.42e-07 | 3.02e-06 | KIRP |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EFEMP1 | 1.66e+03 | 1.77e+00 | 4.80e-01 | 3.70e+00 | 2.19e-04 | 6.53e-04 | LIHC |
| EFEMP1 | 3.63e+03 | -1.59e+00 | 4.66e-01 | -3.42e+00 | 6.31e-04 | 1.44e-03 | KICH |
| EFEMP1 | 7.68e+03 | -1.93e+00 | 1.33e-01 | -1.45e+01 | 1.17e-47 | 1.11e-46 | BRCA |
| EFEMP1 | 1.47e+03 | -1.54e+00 | 5.09e-01 | -3.02e+00 | 2.55e-03 | 7.78e-03 | READ |
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Sex-biased somatic mutation for EFEMP1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for EFEMP1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg20786074 | chr2:55923120 | CGI:chr2:55923205-55923813 | promoter,gene body | 4.00e-01 | 2.68e-01 | 2.93e+00 | 3.35e-03 | 4.53e-03 | 1.32e-01 |
| LUAD | cg23260993 | chr2:55922329 | CGI:chr2:55923205-55923813 | promoter,exon,gene body | 6.64e-01 | 3.67e-01 | 4.89e+00 | 1.03e-06 | 6.92e-06 | 2.96e-01 |
| LUSC | cg23260993 | chr2:55922329 | CGI:chr2:55923205-55923813 | promoter,exon,gene body | 6.06e-01 | 4.12e-01 | 2.27e+00 | 2.32e-02 | 2.69e-02 | 1.94e-01 |
| LUSC | cg25711779 | chr2:55922690 | CGI:chr2:55923205-55923813 | UTR,promoter,exon,gene body | 4.12e-01 | 2.63e-01 | 2.44e+00 | 1.45e-02 | 1.85e-02 | 1.49e-01 |
| LUSC | cg20786074 | chr2:55923120 | CGI:chr2:55923205-55923813 | promoter,gene body | 3.56e-01 | 1.94e-01 | 2.36e+00 | 1.83e-02 | 2.22e-02 | 1.63e-01 |
| BLCA | cg23260993 | chr2:55922329 | CGI:chr2:55923205-55923813 | promoter,exon,gene body | 7.06e-01 | 6.00e-01 | 2.54e+00 | 1.11e-02 | 1.54e-02 | 1.06e-01 |
| BLCA | cg20786074 | chr2:55923120 | CGI:chr2:55923205-55923813 | promoter,gene body | 4.14e-01 | 2.70e-01 | 2.12e+00 | 3.42e-02 | 3.72e-02 | 1.44e-01 |
| ESCA | cg23260993 | chr2:55922329 | CGI:chr2:55923205-55923813 | promoter,exon,gene body | 7.27e-01 | 6.22e-01 | 2.18e+00 | 2.90e-02 | 4.34e-02 | 1.05e-01 |
| CHOL | cg25711779 | chr2:55922690 | CGI:chr2:55923205-55923813 | UTR,promoter,exon,gene body | 5.94e-01 | 4.52e-01 | 2.51e+00 | 1.22e-02 | 2.39e-02 | 1.42e-01 |
| CHOL | cg20786074 | chr2:55923120 | CGI:chr2:55923205-55923813 | promoter,gene body | 6.27e-01 | 3.54e-01 | 2.65e+00 | 7.96e-03 | 1.92e-02 | 2.73e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg24719005 | chr2:55923540 | CGI:chr2:55923205-55923813 | promoter,gene body | 1.75e-01 | 6.94e-02 | 7.23e+00 | 4.81e-13 | 1.51e-12 | 1.05e-01 |
| BRCA | cg23260993 | chr2:55922329 | CGI:chr2:55923205-55923813 | promoter,exon,gene body | 7.89e-01 | 6.65e-01 | 9.17e+00 | 4.87e-20 | 2.64e-19 | 1.25e-01 |
| BRCA | cg25711779 | chr2:55922690 | CGI:chr2:55923205-55923813 | UTR,promoter,exon,gene body | 5.83e-01 | 4.27e-01 | 1.01e+01 | 5.70e-24 | 4.39e-23 | 1.55e-01 |
| BRCA | cg20786074 | chr2:55923120 | CGI:chr2:55923205-55923813 | promoter,gene body | 6.16e-01 | 3.49e-01 | 1.07e+01 | 7.30e-27 | 7.45e-26 | 2.67e-01 |
| BRCA | cg03122624 | chr2:55923206 | CGI:chr2:55923205-55923813 | promoter,gene body | 4.00e-01 | 1.79e-01 | 9.42e+00 | 4.41e-21 | 2.61e-20 | 2.21e-01 |
| BRCA | cg16100120 | chr2:55923340 | CGI:chr2:55923205-55923813 | promoter,gene body | 4.60e-01 | 1.56e-01 | 1.00e+01 | 1.57e-23 | 1.16e-22 | 3.04e-01 |
| BRCA | cg05385513 | chr2:55923343 | CGI:chr2:55923205-55923813 | promoter,gene body | 5.30e-01 | 1.81e-01 | 1.05e+01 | 1.10e-25 | 9.95e-25 | 3.48e-01 |
| BRCA | cg25046074 | chr2:55923414 | CGI:chr2:55923205-55923813 | promoter,gene body | 2.03e-01 | 8.14e-02 | 8.37e+00 | 5.73e-17 | 2.43e-16 | 1.22e-01 |
| LIHC | cg23260993 | chr2:55922329 | CGI:chr2:55923205-55923813 | promoter,exon,gene body | 6.04e-01 | 4.10e-01 | 3.29e+00 | 1.01e-03 | 2.28e-03 | 1.94e-01 |
| LIHC | cg25711779 | chr2:55922690 | CGI:chr2:55923205-55923813 | UTR,promoter,exon,gene body | 4.78e-01 | 3.45e-01 | 3.12e+00 | 1.78e-03 | 3.56e-03 | 1.33e-01 |
| LIHC | cg03122624 | chr2:55923206 | CGI:chr2:55923205-55923813 | promoter,gene body | 2.30e-01 | 1.21e-01 | 2.65e+00 | 7.96e-03 | 1.16e-02 | 1.10e-01 |
| LIHC | cg16100120 | chr2:55923340 | CGI:chr2:55923205-55923813 | promoter,gene body | 3.00e-01 | 1.06e-01 | 2.67e+00 | 7.53e-03 | 1.11e-02 | 1.94e-01 |
Top |
Exon skipping events with PSI in TCGA for EFEMP1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| LUSC | exon_skip_339323 | 2.78e-01 | 3.80e-01 | -4.38e+00 | 1.18e-05 | 8.46e-05 | -1.03e-01 |
Top |
RNA A-to-I editing events in TCGA for EFEMP1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for EFEMP1 |
| TFs related to EFEMP1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | ZNF418 | EFEMP1 | 2.93e+00 | 3.94e-03 | 4.09e+00 | 9.85e-01 | Female-biased |
| MESO | ZNF418 | EFEMP1 | 3.78e+00 | 1.13e-02 | 5.02e+00 | 9.85e-01 | Female-biased |
| PCPG | DMRT2 | EFEMP1 | 4.62e+00 | 9.91e-01 | 3.53e+00 | 2.73e-03 | Male-biased |
| PCPG | FOXF1 | EFEMP1 | 4.09e+00 | 9.84e-01 | 2.99e+00 | 2.46e-03 | Male-biased |
| PCPG | HMX1 | EFEMP1 | 4.64e+00 | 9.90e-01 | 3.65e+00 | 4.19e-03 | Male-biased |
| PCPG | HMX2 | EFEMP1 | 4.74e+00 | 9.84e-01 | 3.97e+00 | 1.12e-02 | Male-biased |
| PCPG | HOXC10 | EFEMP1 | 4.18e+00 | 9.84e-01 | 3.19e+00 | 4.10e-03 | Male-biased |
| PCPG | MEIS1 | EFEMP1 | 4.55e+00 | 9.84e-01 | 3.73e+00 | 9.20e-03 | Male-biased |
| PCPG | POU3F3 | EFEMP1 | 4.29e+00 | 9.89e-01 | 3.02e+00 | 1.11e-03 | Male-biased |
| PCPG | POU5F1 | EFEMP1 | 4.19e+00 | 9.85e-01 | 3.14e+00 | 3.17e-03 | Male-biased |
| SKCM | DMRT2 | EFEMP1 | 3.51e+00 | 1.38e-03 | 5.11e+00 | 9.93e-01 | Female-biased |
| SKCM | FOXF1 | EFEMP1 | 3.12e+00 | 1.78e-03 | 4.64e+00 | 9.87e-01 | Female-biased |
| SKCM | FOXG1 | EFEMP1 | 2.54e+00 | 6.08e-04 | 4.36e+00 | 9.83e-01 | Female-biased |
| SKCM | FOXJ3 | EFEMP1 | 2.79e+00 | 1.52e-03 | 4.34e+00 | 9.82e-01 | Female-biased |
| SKCM | FOXL1 | EFEMP1 | 2.46e+00 | 4.69e-04 | 4.35e+00 | 9.83e-01 | Female-biased |
| SKCM | FOXR2 | EFEMP1 | 2.58e+00 | 3.09e-04 | 4.59e+00 | 9.88e-01 | Female-biased |
| SKCM | HMX1 | EFEMP1 | 3.58e+00 | 2.25e-03 | 5.04e+00 | 9.91e-01 | Female-biased |
| SKCM | HMX2 | EFEMP1 | 3.99e+00 | 6.04e-03 | 5.13e+00 | 9.88e-01 | Female-biased |
| SKCM | HOXC10 | EFEMP1 | 3.09e+00 | 1.26e-03 | 4.71e+00 | 9.89e-01 | Female-biased |
| SKCM | HSF5 | EFEMP1 | 4.43e+00 | 9.08e-03 | 5.44e+00 | 9.88e-01 | Female-biased |
| SKCM | IRX2 | EFEMP1 | 4.40e+00 | 1.02e-02 | 5.38e+00 | 9.86e-01 | Female-biased |
| SKCM | MEF2B | EFEMP1 | 4.02e+00 | 7.05e-03 | 5.12e+00 | 9.87e-01 | Female-biased |
| SKCM | MEIS1 | EFEMP1 | 3.75e+00 | 4.52e-03 | 4.99e+00 | 9.89e-01 | Female-biased |
| SKCM | POU2F1 | EFEMP1 | 3.30e+00 | 3.41e-03 | 4.61e+00 | 9.85e-01 | Female-biased |
| SKCM | POU3F3 | EFEMP1 | 3.07e+00 | 5.25e-04 | 4.94e+00 | 9.92e-01 | Female-biased |
| SKCM | POU5F1 | EFEMP1 | 3.19e+00 | 2.10e-03 | 4.66e+00 | 9.87e-01 | Female-biased |
| SKCM | PRDM1 | EFEMP1 | 3.22e+00 | 4.52e-03 | 4.45e+00 | 9.81e-01 | Female-biased |
| SKCM | TBP | EFEMP1 | 3.12e+00 | 2.70e-03 | 4.51e+00 | 9.84e-01 | Female-biased |
| SKCM | ZBTB32 | EFEMP1 | 5.11e+00 | 8.87e-03 | 6.13e+00 | 9.90e-01 | Female-biased |
| SKCM | ZFHX3 | EFEMP1 | 5.13e+00 | 1.05e-02 | 6.10e+00 | 9.88e-01 | Female-biased |
| SKCM | ZNF136 | EFEMP1 | 3.30e+00 | 3.89e-03 | 4.57e+00 | 9.84e-01 | Female-biased |
| SKCM | ZNF260 | EFEMP1 | 3.04e+00 | 3.13e-03 | 4.38e+00 | 9.81e-01 | Female-biased |
| SKCM | ZNF418 | EFEMP1 | 1.65e+00 | 2.95e-05 | 4.32e+00 | 9.83e-01 | Female-biased |
| SKCM | ZNF79 | EFEMP1 | 2.40e+00 | 2.18e-04 | 4.50e+00 | 9.87e-01 | Female-biased |
| EFEMP1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for EFEMP1 |
| RBPs related to ES in EFEMP1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| COAD | HNRNPA2B1 | exon_skip_339284 | 8.10e+00 | 5.98e-03 | 8.47e+00 | 9.87e-01 | Female-biased |
| COAD | YBX2 | exon_skip_339284 | 9.61e+00 | 2.57e-03 | 1.01e+01 | 9.96e-01 | Female-biased |
| LUAD | MSI1 | exon_skip_339301 | 1.51e+01 | 9.99e-01 | 1.45e+01 | 9.10e-04 | Male-biased |
| BRCA | MSI1 | exon_skip_339301 | 1.53e+01 | 9.92e-01 | 1.47e+01 | 8.09e-03 | Male-biased |
| ESCA | HNRNPA2B1 | exon_skip_339284 | 7.85e+00 | 9.52e-03 | 8.30e+00 | 9.83e-01 | Female-biased |
| READ | HNRNPA2B1 | exon_skip_339284 | 8.41e+00 | 9.82e-01 | 8.09e+00 | 1.09e-02 | Male-biased |
| READ | YBX2 | exon_skip_339284 | 1.02e+01 | 9.95e-01 | 9.72e+00 | 3.27e-03 | Male-biased |
| THCA | MSI1 | exon_skip_339302 | 1.51e+01 | 1.00e+00 | 1.44e+01 | 5.68e-05 | Male-biased |
| MESO | ZC3H10 | exon_skip_339302 | 7.11e+00 | 9.83e-01 | 6.66e+00 | 3.82e-03 | Male-biased |
| GBM | MSI1 | exon_skip_339301 | 1.46e+01 | 7.99e-04 | 1.52e+01 | 9.99e-01 | Female-biased |
| GBM | ZC3H10 | exon_skip_339301 | 6.97e+00 | 7.44e-03 | 7.33e+00 | 9.81e-01 | Female-biased |
| PAAD | ZC3H10 | exon_skip_339302 | 7.19e+00 | 9.81e-01 | 6.87e+00 | 6.95e-03 | Male-biased |
| KIRC | MSI1 | exon_skip_339301 | 1.41e+01 | 3.93e-04 | 1.48e+01 | 1.00e+00 | Female-biased |
| EFEMP1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000115380 | AC027307.3,hsa-mir-338,EFEMP1 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000115380 | HAGLR,hsa-mir-338,EFEMP1 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000115380 | LINC01503,hsa-mir-338,EFEMP1 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000115380 | AP002761.4,hsa-mir-452,EFEMP1 | Tumor-specific sex-biased ceRNA | TCGA-KIRP |
| ENSG00000115380 | AC137932.2,hsa-mir-338,EFEMP1 | Female-specific ceRNA | TCGA-LIHC |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2931462 | chr2:54678657:T:C | - | 0.110284441328961 | 0.0313964724690815 | LIHC | Female-baised eQTL |
| rs354221 | chr2:54698542:C:T | - | 0.106140821103564 | 0.0403191227237749 | LIHC | Female-baised eQTL |
| rs354219 | chr2:54699007:C:T | - | 0.106140821103564 | 0.0403191227237749 | LIHC | Female-baised eQTL |
| rs187123 | chr2:54705027:T:A | - | 0.106140821103564 | 0.0403191227237749 | LIHC | Female-baised eQTL |
| rs111768350 | chr2:48552735:A:G | - | 0.124300008194276 | 0.00767216141963503 | LUSC | Female-baised eQTL |
| rs11683259 | chr2:48553648:T:C | - | 0.124300008194276 | 0.00767216141963503 | LUSC | Female-baised eQTL |
| rs11688465 | chr2:48553688:A:G | - | 0.123902839812008 | 0.00822903479573512 | LUSC | Female-baised eQTL |
| rs62136907 | chr2:54812433:G:C | - | 0.116889266275402 | 0.0148925568385169 | LUSC | Female-baised eQTL |
| rs79760528 | chr2:48567012:G:A | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs74604130 | chr2:48568655:A:G | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs78306225 | chr2:48568818:C:T | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs17325698 | chr2:48571488:C:A | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs76062057 | chr2:48573770:C:G | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs187502057 | chr2:48575524:A:T | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs193155482 | chr2:48575584:C:T | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs190734523 | chr2:48575606:T:C | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs111403319 | chr2:48576047:C:T | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs77337164 | chr2:48576627:C:G | - | 0.122439816748047 | 0.0157846371434163 | LUSC | Female-baised eQTL |
| rs75011510 | chr2:48572461:A:C | - | 0.122383667793255 | 0.0160095003092395 | LUSC | Female-baised eQTL |
| rs74955566 | chr2:53906953:G:T | - | 0.095427203006482 | 0.0174637178487635 | LUSC | Female-baised eQTL |
| rs1363061 | chr2:54057304:G:A | - | 0.0936499205903418 | 0.0244906341683166 | LUSC | Female-baised eQTL |
| rs62136882 | chr2:54794524:A:G | - | 0.10590510378176 | 0.0251159760108586 | LUSC | Female-baised eQTL |
| rs145773156 | chr2:54031282:C:A | - | 0.0927223176417289 | 0.0278375775515282 | LUSC | Female-baised eQTL |
| rs79591643 | chr2:48545526:G:A | - | 0.121273771140375 | 0.0280531019058564 | LUSC | Female-baised eQTL |
| rs11686769 | chr2:48455374:T:C | - | 0.0946683046777843 | 0.0302314591826987 | LUSC | Female-baised eQTL |
| rs182792226 | chr2:54069519:G:A | - | 0.0919309978265775 | 0.0317923635868692 | LUSC | Female-baised eQTL |
| rs11690526 | chr2:48512093:G:A | - | 0.113895682481391 | 0.0321349724704802 | LUSC | Female-baised eQTL |
| rs11693784 | chr2:48514246:C:T | - | 0.113895682481391 | 0.0321349724704802 | LUSC | Female-baised eQTL |
| rs184530337 | chr2:48517789:T:C | - | 0.113895682481391 | 0.0321349724704802 | LUSC | Female-baised eQTL |
| rs111906644 | chr2:48517845:A:G | - | 0.113895682481391 | 0.0321349724704802 | LUSC | Female-baised eQTL |
| rs10432679 | chr2:59089677:A:G | - | 0.106158062825357 | 0.0326888097930049 | LUSC | Female-baised eQTL |
| rs10432680 | chr2:59089680:T:G | - | 0.106158062825357 | 0.0326888097930049 | LUSC | Female-baised eQTL |
| rs17268200 | chr2:54054714:A:G | - | 0.0916573635645072 | 0.0331053566323155 | LUSC | Female-baised eQTL |
| rs76435603 | chr2:48487290:G:A | - | 0.110641450097893 | 0.0331747181188063 | LUSC | Female-baised eQTL |
| rs74654613 | chr2:48456184:T:C | - | 0.0886092670747237 | 0.0360576132859054 | LUSC | Female-baised eQTL |
| rs17190576 | chr2:58637620:G:A | - | 0.107814029797463 | 0.0389051552401997 | LUSC | Female-baised eQTL |
| rs7571146 | chr2:64935184:C:T | - | 0.0898546150542642 | 0.0406313160834263 | LUSC | Female-baised eQTL |
| rs142578819 | chr2:48456920:T:C | - | 0.0926804373911512 | 0.042568587171453 | LUSC | Female-baised eQTL |
| rs115908081 | chr2:58718943:C:T | - | 0.102538784842203 | 0.0428852071115122 | LUSC | Female-baised eQTL |
| rs6743266 | chr2:53266159:T:A | - | 0.138251631769697 | 0.007033048515335 | LGG | Female-baised eQTL |
| rs10495940 | chr2:46919593:A:C | - | 0.132693796584078 | 0.00374582708051224 | BLCA | Female-baised eQTL |
| rs6741399 | chr2:46920706:A:G | - | 0.132693796584078 | 0.00374582708051224 | BLCA | Female-baised eQTL |
| rs6717185 | chr2:46921814:C:T | - | 0.132693796584078 | 0.00374582708051224 | BLCA | Female-baised eQTL |
| rs72886669 | chr2:46925769:C:G | - | 0.132693796584078 | 0.00374582708051224 | BLCA | Female-baised eQTL |
| rs7570279 | chr2:46927517:C:T | - | 0.132693796584078 | 0.00374582708051224 | BLCA | Female-baised eQTL |
| rs60630351 | chr2:46929852:C:G | - | 0.132693796584078 | 0.00374582708051224 | BLCA | Female-baised eQTL |
| rs71407570 | chr2:49619355:G:A | - | 0.13041976232993 | 0.00870122903201161 | BLCA | Female-baised eQTL |
| rs60675270 | chr2:49620837:C:A | - | 0.130219197485995 | 0.0093955876106534 | BLCA | Female-baised eQTL |
| rs60962761 | chr2:47003750:C:T | - | 0.106706992532012 | 0.0119949626994576 | BLCA | Female-baised eQTL |
| rs1814276 | chr2:56180912:G:C | - | -0.0863837117503781 | 0.0223444911633951 | BLCA | Female-baised eQTL |
| rs6735241 | chr2:56181788:G:C | - | -0.0863837117503781 | 0.0223444911633951 | BLCA | Female-baised eQTL |
| rs960490 | chr2:56184022:T:C | - | -0.0870448186965021 | 0.02387438684469 | BLCA | Female-baised eQTL |
| rs960489 | chr2:56184228:G:A | - | -0.0870448186965021 | 0.02387438684469 | BLCA | Female-baised eQTL |
| rs4672096 | chr2:56186210:G:T | - | -0.0870619622834592 | 0.0241238314229106 | BLCA | Female-baised eQTL |
| rs17044784 | chr2:53472252:C:T | - | 0.11431885887302 | 0.029657051755469 | BLCA | Female-baised eQTL |
| rs6759361 | chr2:53490884:C:A | - | 0.111235538345383 | 0.0427935665314834 | BLCA | Female-baised eQTL |
| rs6704836 | chr2:53490950:C:T | - | 0.111235538345383 | 0.0427935665314834 | BLCA | Female-baised eQTL |
| rs72908995 | chr2:53493651:G:A | - | 0.111235538345383 | 0.0427935665314834 | BLCA | Female-baised eQTL |
| rs9784047 | chr2:53493879:C:T | - | 0.111235538345383 | 0.0427935665314834 | BLCA | Female-baised eQTL |
| rs6720273 | chr2:53490966:T:C | - | 0.110994871166641 | 0.0441969486666416 | BLCA | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2194800 | chr2:56506755:T:A | - | 0.274387062792864 | 0.0110543908181596 | PCPG | Male-baised eQTL |
| rs13404912 | chr2:56508387:C:T | - | 0.274387062792864 | 0.0110543908181596 | PCPG | Male-baised eQTL |
| rs13406625 | chr2:56494872:T:C | - | 0.273792712488089 | 0.0117582088003587 | PCPG | Male-baised eQTL |
| rs58155956 | chr2:52788976:C:G | - | 0.0536645061749773 | 0.00605286359671526 | LUSC | Male-baised eQTL |
| rs7570110 | chr2:52792262:A:C | - | 0.0536559838714613 | 0.00610037452248413 | LUSC | Male-baised eQTL |
| rs62127041 | chr2:52790431:C:T | - | 0.0526751321136104 | 0.00871026915500116 | LUSC | Male-baised eQTL |
| rs62138394 | chr2:53038099:T:C | - | 0.0699320162573723 | 0.00970742152733863 | LUSC | Male-baised eQTL |
| rs7592395 | chr2:52787621:T:C | - | 0.0510708915326037 | 0.0125262990324243 | LUSC | Male-baised eQTL |
| rs116247941 | chr2:52769393:C:T | - | 0.0523614386687541 | 0.0128093427196124 | LUSC | Male-baised eQTL |
| rs2081376 | chr2:52349175:G:C | - | -0.0539745422851791 | 0.0138585499558258 | LUSC | Male-baised eQTL |
| rs62127043 | chr2:52791401:G:C | - | 0.0531060144849417 | 0.0148264880115596 | LUSC | Male-baised eQTL |
| rs7607947 | chr2:52788076:A:G | - | 0.0490136540974436 | 0.0165598793445353 | LUSC | Male-baised eQTL |
| rs61366192 | chr2:52788934:T:C | - | 0.0490136540974436 | 0.0165598793445353 | LUSC | Male-baised eQTL |
| rs62127045 | chr2:52791581:C:G | - | 0.0490136540974436 | 0.0165598793445353 | LUSC | Male-baised eQTL |
| rs55813800 | chr2:52788973:T:C | - | 0.0482671427986691 | 0.0171993130116462 | LUSC | Male-baised eQTL |
| rs62138401 | chr2:53095529:G:T | - | 0.0657510797165439 | 0.019299053767995 | LUSC | Male-baised eQTL |
| rs59739978 | chr2:52787366:G:A | - | 0.0478741576693341 | 0.022343106380684 | LUSC | Male-baised eQTL |
| rs35762589 | chr2:53019779:G:C | - | 0.0474304193111502 | 0.0276194658722199 | LUSC | Male-baised eQTL |
| rs56011264 | chr2:52787299:A:C | - | 0.0467155508453836 | 0.0299871753372474 | LUSC | Male-baised eQTL |
| rs62127036 | chr2:52787527:C:A | - | 0.0467155508453836 | 0.0299871753372474 | LUSC | Male-baised eQTL |
| rs62127037 | chr2:52787552:G:C | - | 0.0467155508453836 | 0.0299871753372474 | LUSC | Male-baised eQTL |
| rs7592503 | chr2:52787717:T:C | - | 0.0466221347939441 | 0.0311072453318581 | LUSC | Male-baised eQTL |
| rs55868236 | chr2:52769985:C:T | - | 0.0480677239128407 | 0.0323924430719917 | LUSC | Male-baised eQTL |
| rs1598155 | chr2:52770511:C:T | - | 0.0480677239128407 | 0.0323924430719917 | LUSC | Male-baised eQTL |
| rs62127011 | chr2:52773360:A:G | - | 0.0516336247538428 | 0.0334676928650726 | LUSC | Male-baised eQTL |
| rs72806390 | chr2:52777305:G:C | - | 0.0505058168744807 | 0.0349629225479194 | LUSC | Male-baised eQTL |
| rs62127030 | chr2:52778775:G:C | - | 0.0505058168744807 | 0.0349629225479194 | LUSC | Male-baised eQTL |
| rs62127010 | chr2:52772946:C:T | - | 0.0503564945856385 | 0.0365232961918034 | LUSC | Male-baised eQTL |
| rs62127012 | chr2:52775422:A:G | - | 0.0503564945856385 | 0.0365232961918034 | LUSC | Male-baised eQTL |
| rs55755324 | chr2:52779664:C:T | - | 0.0473368244512631 | 0.0375393023789035 | LUSC | Male-baised eQTL |
| rs72806386 | chr2:52776538:T:C | - | 0.0489010782012275 | 0.0495563681809771 | LUSC | Male-baised eQTL |
| rs78597273 | chr2:48380665:G:A | - | 0.0499685687510826 | 0.042017307450658 | LGG | Male-baised eQTL |
| rs12994146 | chr2:50173283:C:G | - | 0.0762416205892824 | 0.045831013715959 | LGG | Male-baised eQTL |
| rs10198941 | chr2:47049060:G:A | - | 0.0727331488624983 | 0.015317727798489 | KIRC | Male-baised eQTL |
| rs4953450 | chr2:47046912:T:C | - | 0.0621467183457193 | 0.0234453925492975 | KIRC | Male-baised eQTL |
| rs17189463 | chr2:53509754:A:C | - | 0.030595238519984 | 0.0481958823457493 | KIRC | Male-baised eQTL |
| rs60060643 | chr2:46859288:C:T | - | 0.0588282340140645 | 0.0498903303244299 | KIRC | Male-baised eQTL |
| rs6709188 | chr2:46859645:G:A | - | 0.0588282340140645 | 0.0498903303244299 | KIRC | Male-baised eQTL |
| rs10211332 | chr2:50478448:C:T | - | 0.0308945057987392 | 0.0344556833825802 | BLCA | Male-baised eQTL |
| rs11893242 | chr2:59381269:G:T | - | 0.152262896354532 | 0.000666518614356816 | LUAD | Male-baised eQTL |
| rs4580429 | chr2:46664315:C:G | - | 0.0909177449445376 | 0.00931398032044251 | LUAD | Male-baised eQTL |
| rs17267852 | chr2:53174162:C:G | - | 0.144362807970286 | 0.0172122659951419 | LUAD | Male-baised eQTL |
| rs7602941 | chr2:56297043:G:A | - | 0.0864813229068513 | 0.0338804040182164 | LUAD | Male-baised eQTL |
| rs79071733 | chr2:53147859:A:G | - | 0.15068629290507 | 0.0433893823636774 | LUAD | Male-baised eQTL |
| rs17189245 | chr2:53150129:G:C | - | 0.150498493949216 | 0.0438639955337777 | LUAD | Male-baised eQTL |
| rs60621045 | chr2:53159816:T:C | - | 0.150498493949216 | 0.0438639955337777 | LUAD | Male-baised eQTL |
| rs79783951 | chr2:53161097:C:T | - | 0.150437842616125 | 0.0441560588373896 | LUAD | Male-baised eQTL |
| rs1963249 | chr2:46665640:G:A | - | 0.0795146412276537 | 0.0484054789195704 | LUAD | Male-baised eQTL |
| rs71413277 | chr2:54852557:T:G | - | 0.0933556015741823 | 0.0030588672856672 | COAD | Male-baised eQTL |
| rs77739453 | chr2:54849768:G:A | - | 0.0851468067528789 | 0.00744936896787283 | COAD | Male-baised eQTL |
| rs13005511 | chr2:54846291:T:C | - | 0.0809922840113235 | 0.0117512488068922 | COAD | Male-baised eQTL |
| rs56189833 | chr2:53643999:C:T | - | 0.0642359724269864 | 0.0147704443518862 | COAD | Male-baised eQTL |
| rs17045215 | chr2:53770021:C:A | - | 0.0642930136353493 | 0.0265392071585618 | COAD | Male-baised eQTL |
| rs55958328 | chr2:53824363:G:T | - | 0.0473785596164889 | 0.0281293029409868 | COAD | Male-baised eQTL |
| rs994484 | chr2:53669630:G:C | - | 0.0531605484295655 | 0.0325857167440016 | COAD | Male-baised eQTL |
| rs79828424 | chr2:53852369:C:T | - | 0.0577056313361731 | 0.0341923367305962 | COAD | Male-baised eQTL |
| rs148352210 | chr2:53852450:G:A | - | 0.0577056313361731 | 0.0341923367305962 | COAD | Male-baised eQTL |
| rs805371 | chr2:53857108:C:T | - | 0.0577056313361731 | 0.0341923367305962 | COAD | Male-baised eQTL |
| rs6720298 | chr2:53871785:G:A | - | 0.0577056313361731 | 0.0341923367305962 | COAD | Male-baised eQTL |
| rs3821078 | chr2:53855831:T:C | - | 0.0552023908186104 | 0.0470879622164364 | COAD | Male-baised eQTL |
| rs3770389 | chr2:53856567:T:A | - | 0.0552023908186104 | 0.0470879622164364 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs13016641 | chr2:56601267:C:G | Distant upstream | 0.0428178679860534 | 0.047193492116227 | LGG | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72815908 | chr2:56030758:G:A | Distant upstream | -0.0514718320514958 | 0.0120373914612893 | LUAD | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs752817 | chr2:56031915:C:T | Distant upstream | -0.0513267340119914 | 0.012477823928073 | LUAD | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs13418952 | chr2:56026370:T:G | Distant upstream | -0.0458915279483897 | 0.0333148804783467 | LUAD | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs189152772 | chr2:56162891:T:G | Distant upstream | 0.0550311620082646 | 0.00261447163571668 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs6751834 | chr2:56145530:C:A | Distant upstream | 0.052169779021307 | 0.00678589085747436 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs10490394 | chr2:56146101:A:G | Distant upstream | 0.0496355806947197 | 0.0068335450755782 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs55794437 | chr2:56142945:G:A | Distant upstream | 0.0515920040385489 | 0.00740658740005418 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs1961746 | chr2:56147514:T:A | Distant upstream | 0.0515920040385489 | 0.00740658740005418 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs4672090 | chr2:56144200:G:T | Distant upstream | 0.0504341657664674 | 0.00964020068405077 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs6722720 | chr2:56145112:A:T | Distant upstream | 0.0504341657664674 | 0.00964020068405077 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs55809599 | chr2:56146388:C:T | Distant upstream | 0.0504341657664674 | 0.00964020068405077 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs4672092 | chr2:56146958:G:A | Distant upstream | 0.0504341657664674 | 0.00964020068405077 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72801117 | chr2:56147203:C:T | Distant upstream | 0.0504341657664674 | 0.00964020068405077 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs6743269 | chr2:56142982:G:A | Distant upstream | 0.0438075745801156 | 0.0336533235206301 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72801108 | chr2:56143220:C:G | Distant upstream | 0.0438075745801156 | 0.0336533235206301 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72801110 | chr2:56144196:G:A | Distant upstream | 0.0438075745801156 | 0.0336533235206301 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72801106 | chr2:56136597:C:A | Distant upstream | 0.0438905774388354 | 0.0341034202741246 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs6739384 | chr2:56142078:G:A | Distant upstream | 0.0438905774388354 | 0.0341034202741246 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs150749486 | chr2:56139543:C:T | Distant upstream | 0.0435688050264864 | 0.0343645291169171 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs187015869 | chr2:56139703:A:G | Distant upstream | 0.0435688050264864 | 0.0343645291169171 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs4672087 | chr2:56127557:C:T | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs2021413 | chr2:56128137:G:A | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72798994 | chr2:56128816:C:T | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs72798995 | chr2:56128833:A:G | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs116360136 | chr2:56128989:A:G | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs146094479 | chr2:56129323:A:G | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs17189988 | chr2:56129451:G:A | Distant upstream | 0.0436191752855746 | 0.0369532808440476 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs1432555 | chr2:56132194:T:A | Distant upstream | 0.0432591182777381 | 0.0380958410353714 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs140087357 | chr2:56139044:G:A | Distant upstream | 0.0432591182777381 | 0.0380958410353714 | THCA | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs2920871 | chr2:55092862:T:G | Distant downstream | 0.0505104461657919 | 0.00575610997978323 | HNSC | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs58482670 | chr2:55033426:C:G | Distant downstream | -0.0569322401379723 | 0.00946057989616886 | HNSC | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs1344733 | chr2:55900892:T:C | Distant downstream | -0.022702155449008 | 0.030721309428524 | HNSC | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs3791662 | chr2:55902498:C:T | Distant downstream | -0.0223344327539564 | 0.036128520087927 | HNSC | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs3828239 | chr2:55901165:A:T | Distant downstream | -0.021708825119823 | 0.0448306427915067 | HNSC | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs7597360 | chr2:56014162:C:T | Distant upstream | -0.0243854486078184 | 0.0491512791228691 | HNSC | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs62165193 | chr2:55566785:C:T | Distant downstream | -0.0893395252471448 | 0.00744508300358318 | PAAD | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs62165231 | chr2:55676526:C:T | Distant downstream | -0.0808027148785736 | 0.0404618378063354 | PAAD | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs62165235 | chr2:55693528:T:C | Distant downstream | -0.0808027148785736 | 0.0404618378063354 | PAAD | Male-baised sQTL |
| exon_skip_339323 | chr2:55922898:55922939 | 3UTR-3UTR | rs62165236 | chr2:55695941:T:C | Distant downstream | -0.0808027148785736 | 0.0404618378063354 | PAAD | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of EFEMP1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000115380 | EFEMP1 | C0001418 | Adenocarcinoma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0007097 | Carcinoma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0009402 | Colorectal Carcinoma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0030297 | Pancreatic Neoplasm | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205641 | Adenocarcinoma, Basal Cell | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205642 | Adenocarcinoma, Oxyphilic | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205643 | Carcinoma, Cribriform | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205644 | Carcinoma, Granular Cell | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205645 | Adenocarcinoma, Tubular | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205696 | Anaplastic carcinoma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205697 | Carcinoma, Spindle-Cell | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205698 | Undifferentiated carcinoma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0205699 | Carcinomatosis | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0346647 | Malignant neoplasm of pancreas | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C1257925 | Mammary Carcinoma, Animal | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C1832174 | DOYNE HONEYCOMB RETINAL DYSTROPHY | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C1852020 | Malattia Leventinese | 1 | CTD_human |
| ENSG00000115380 | EFEMP1 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
