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Gene: ENSG00000114638 |
Summary for UPK1B |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000114638 | Gene symbol | UPK1B |
| Gene name | uroplakin 1B | |
| HGNC | 12578 | |
| Entrez ID | 7348 | |
| Gene type | protein_coding | |
| Synonyms | UPK1B|TSPAN20 | |
| UniProtAcc | O75841 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for UPK1B |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| UPK1B | 1.67e+02 | 1.72e+00 | 2.86e-01 | 6.02e+00 | 1.78e-09 | 2.23e-07 | LUAD |
| UPK1B | 3.23e+03 | 1.54e+00 | 3.24e-01 | 4.75e+00 | 2.08e-06 | 7.59e-05 | HNSC |
| UPK1B | 1.80e+02 | -2.28e+00 | 4.20e-01 | -5.45e+00 | 5.17e-08 | 2.22e-05 | THYM |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| UPK1B | 2.39e+02 | 3.83e+00 | 7.18e-01 | 5.33e+00 | 9.84e-08 | 4.07e-07 | LUAD |
| UPK1B | 1.59e+03 | 2.23e+00 | 4.41e-01 | 5.06e+00 | 4.28e-07 | 1.61e-06 | KIRP |
| UPK1B | 1.37e+03 | 2.41e+00 | 9.77e-01 | 2.47e+00 | 1.35e-02 | 4.74e-02 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| UPK1B | 6.23e+02 | -2.15e+00 | 8.91e-01 | -2.42e+00 | 1.57e-02 | 4.93e-02 | STAD |
| UPK1B | 1.53e+02 | -8.49e+00 | 5.76e-01 | -1.47e+01 | 3.77e-49 | 1.24e-46 | KICH |
Top |
Sex-biased somatic mutation for UPK1B |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for UPK1B |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg02741226 | chr3:119173458 | CGI:chr3:119240492-119241087 | promoter | 4.71e-01 | 3.24e-01 | 3.71e+00 | 2.06e-04 | 3.85e-04 | 1.48e-01 |
| KIRC | cg02019333 | chr3:119173368 | CGI:chr3:119240492-119241087 | promoter | 4.81e-01 | 3.53e-01 | 3.13e+00 | 1.76e-03 | 2.56e-03 | 1.28e-01 |
| KIRC | cg01814130 | chr3:119173483 | CGI:chr3:119240492-119241087 | promoter | 5.60e-01 | 4.36e-01 | 2.81e+00 | 4.99e-03 | 6.44e-03 | 1.24e-01 |
| THCA | cg02741226 | chr3:119173458 | CGI:chr3:119240492-119241087 | promoter | 5.23e-01 | 4.09e-01 | 2.92e+00 | 3.46e-03 | 7.71e-03 | 1.14e-01 |
| THCA | cg01814130 | chr3:119173483 | CGI:chr3:119240492-119241087 | promoter | 6.39e-01 | 5.13e-01 | 3.46e+00 | 5.37e-04 | 2.00e-03 | 1.26e-01 |
| LIHC | cg02019333 | chr3:119173368 | CGI:chr3:119240492-119241087 | promoter | 4.88e-01 | 6.86e-01 | -3.87e+00 | 1.07e-04 | 2.20e-04 | -1.98e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02741226 | chr3:119173458 | CGI:chr3:119240492-119241087 | promoter | 6.33e-01 | 4.93e-01 | 9.12e+00 | 7.72e-20 | 4.12e-19 | 1.40e-01 |
| KIRC | cg22842233 | chr3:119173221 | CGI:chr3:119240492-119241087 | promoter | 9.12e-01 | 8.10e-01 | 3.56e+00 | 3.64e-04 | 3.12e-03 | 1.02e-01 |
| LUAD | cg01814130 | chr3:119173483 | CGI:chr3:119240492-119241087 | promoter | 7.11e-01 | 5.95e-01 | 3.06e+00 | 2.22e-03 | 5.47e-03 | 1.16e-01 |
| HNSC | cg22842233 | chr3:119173221 | CGI:chr3:119240492-119241087 | promoter | 8.39e-01 | 6.66e-01 | 2.79e+00 | 5.21e-03 | 1.36e-02 | 1.72e-01 |
| BLCA | cg02741226 | chr3:119173458 | CGI:chr3:119240492-119241087 | promoter | 4.05e-01 | 5.39e-01 | -2.04e+00 | 4.12e-02 | 4.37e-02 | -1.34e-01 |
| BLCA | cg02019333 | chr3:119173368 | CGI:chr3:119240492-119241087 | promoter | 4.33e-01 | 5.54e-01 | -1.99e+00 | 4.69e-02 | 4.77e-02 | -1.21e-01 |
Top |
Exon skipping events with PSI in TCGA for UPK1B |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for UPK1B |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for UPK1B |
| TFs related to UPK1B. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | POU2F2 | UPK1B | 4.28e+00 | 1.67e-02 | 5.08e+00 | 9.81e-01 | Female-biased |
| ESCA | RELA | UPK1B | 3.92e+00 | 9.83e-01 | 2.97e+00 | 2.56e-03 | Male-biased |
| PAAD | EN1 | UPK1B | 5.78e+00 | 9.80e-01 | 5.07e+00 | 1.87e-02 | Male-biased |
| PAAD | HSFY2 | UPK1B | 5.60e+00 | 9.81e-01 | 4.88e+00 | 1.73e-02 | Male-biased |
| PAAD | MEOX2 | UPK1B | 5.31e+00 | 9.93e-01 | 4.34e+00 | 5.32e-03 | Male-biased |
| PAAD | POU2F1 | UPK1B | 5.11e+00 | 9.84e-01 | 4.34e+00 | 1.35e-02 | Male-biased |
| PAAD | POU2F2 | UPK1B | 5.28e+00 | 9.93e-01 | 4.31e+00 | 5.07e-03 | Male-biased |
| PAAD | POU2F3 | UPK1B | 5.62e+00 | 9.80e-01 | 4.91e+00 | 1.82e-02 | Male-biased |
| PAAD | POU3F3 | UPK1B | 5.04e+00 | 9.96e-01 | 3.82e+00 | 1.41e-03 | Male-biased |
| PAAD | PRDM1 | UPK1B | 4.66e+00 | 9.89e-01 | 3.71e+00 | 5.57e-03 | Male-biased |
| PAAD | STAT2 | UPK1B | 3.85e+00 | 9.81e-01 | 2.43e+00 | 4.49e-04 | Male-biased |
| PAAD | ZNF146 | UPK1B | 4.58e+00 | 9.86e-01 | 3.70e+00 | 8.06e-03 | Male-biased |
| UVM | EN1 | UPK1B | 3.75e+00 | 6.08e-03 | 5.31e+00 | 9.90e-01 | Female-biased |
| UVM | GBX2 | UPK1B | 4.38e+00 | 1.47e-02 | 5.50e+00 | 9.82e-01 | Female-biased |
| UVM | HSFY2 | UPK1B | 3.79e+00 | 1.01e-02 | 5.09e+00 | 9.84e-01 | Female-biased |
| UVM | MEOX2 | UPK1B | 3.08e+00 | 5.26e-03 | 4.70e+00 | 9.84e-01 | Female-biased |
| UVM | POU2F2 | UPK1B | 2.87e+00 | 2.82e-03 | 4.77e+00 | 9.87e-01 | Female-biased |
| UVM | POU2F3 | UPK1B | 3.60e+00 | 6.49e-03 | 5.13e+00 | 9.88e-01 | Female-biased |
| UVM | POU3F3 | UPK1B | 2.30e+00 | 1.17e-03 | 4.56e+00 | 9.86e-01 | Female-biased |
| UVM | VENTX | UPK1B | 5.20e+00 | 1.47e-02 | 6.32e+00 | 9.84e-01 | Female-biased |
| UVM | ZNF331 | UPK1B | 4.63e+00 | 9.83e-01 | 2.86e+00 | 3.75e-03 | Male-biased |
| UPK1B related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for UPK1B |
| RBPs related to ES in UPK1B. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| UPK1B related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000114638 | AL035661.1,hsa-mir-488,UPK1B | Tumor sex-biased ceRNA | TCGA-SARC |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs790101 | chr3:122651036:T:G | - | 0.234123137786065 | 1.90631153361025e-10 | HNSC | Female-baised eQTL |
| rs2668345 | chr3:122649781:C:G | - | 0.231668619237387 | 5.52036682795118e-09 | HNSC | Female-baised eQTL |
| rs812047 | chr3:122663227:G:C | - | 0.20567577177232 | 3.66266791554136e-08 | HNSC | Female-baised eQTL |
| rs790110 | chr3:122665173:T:G | - | 0.205637556303789 | 3.79159048763203e-08 | HNSC | Female-baised eQTL |
| rs60226894 | chr3:122665305:C:T | - | 0.205637556303789 | 3.79159048763203e-08 | HNSC | Female-baised eQTL |
| rs2668336 | chr3:122665622:T:A | - | 0.205637556303789 | 3.79159048763203e-08 | HNSC | Female-baised eQTL |
| rs790130 | chr3:122665814:C:G | - | 0.205637556303789 | 3.79159048763203e-08 | HNSC | Female-baised eQTL |
| rs796891 | chr3:122667725:T:G | - | 0.193413817436689 | 2.95624815480577e-07 | HNSC | Female-baised eQTL |
| rs9856865 | chr3:117399998:C:T | - | -0.155452087725358 | 0.000277264350821893 | HNSC | Female-baised eQTL |
| rs11716890 | chr3:122634514:A:C | - | 0.107746452025913 | 0.00222531573318202 | HNSC | Female-baised eQTL |
| rs12489170 | chr3:122635945:G:A | - | 0.0956364148415712 | 0.00853837539011591 | HNSC | Female-baised eQTL |
| rs9990259 | chr3:119855943:G:A | - | 0.061182117884326 | 0.0458340603857481 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs79641971 | chr3:117348995:G:A | - | 0.050910727876161 | 0.00082730590561942 | KIRC | Male-baised eQTL |
| rs12633648 | chr3:117326986:C:A | - | 0.0479969908634787 | 0.00153803474640258 | KIRC | Male-baised eQTL |
| rs16826656 | chr3:117338140:A:G | - | 0.0479107017189777 | 0.00160954849355366 | KIRC | Male-baised eQTL |
| rs7644174 | chr3:113003479:G:C | - | 0.0420650016034687 | 0.00562359767298628 | KIRC | Male-baised eQTL |
| rs9865917 | chr3:111448161:G:A | - | 0.0283154613563436 | 0.0281411200711765 | KIRC | Male-baised eQTL |
| rs6766076 | chr3:111502380:G:C | - | 0.0288704437829242 | 0.0301068353521259 | KIRC | Male-baised eQTL |
| rs73198758 | chr3:127043096:G:A | - | 0.10916404749565 | 0.0255986617676582 | BLCA | Male-baised eQTL |
| rs73198753 | chr3:127042238:G:C | - | 0.104802776749916 | 0.0367382046308556 | BLCA | Male-baised eQTL |
| rs11716117 | chr3:127041026:G:T | - | 0.0987570136513877 | 0.0457238340780903 | BLCA | Male-baised eQTL |
| rs34601658 | chr3:125823711:A:G | - | -0.084450656996072 | 0.000219366792047948 | LUAD | Male-baised eQTL |
| rs4510340 | chr3:125822924:C:T | - | -0.0834485870875822 | 0.000264906394557656 | LUAD | Male-baised eQTL |
| rs2979930 | chr3:125823824:T:C | - | -0.0834139012803119 | 0.000272087764658453 | LUAD | Male-baised eQTL |
| rs2020198 | chr3:125824953:G:A | - | -0.0802870943685946 | 0.00053146679560076 | LUAD | Male-baised eQTL |
| rs2971290 | chr3:125828855:G:A | - | -0.0802870943685946 | 0.00053146679560076 | LUAD | Male-baised eQTL |
| rs2971322 | chr3:125726487:G:A | - | -0.0973970530051913 | 0.000646812399288493 | LUAD | Male-baised eQTL |
| rs9833245 | chr3:125726881:C:T | - | -0.0973400801458778 | 0.000661231043681546 | LUAD | Male-baised eQTL |
| rs2976793 | chr3:125728329:T:A | - | -0.0973224721769139 | 0.000664414297323991 | LUAD | Male-baised eQTL |
| rs2976771 | chr3:125716907:G:A | - | -0.0964113174116622 | 0.000683645089148705 | LUAD | Male-baised eQTL |
| rs2979937 | chr3:125829273:C:T | - | -0.0797815009696303 | 0.000693292796225195 | LUAD | Male-baised eQTL |
| rs9283572 | chr3:125724439:G:C | - | -0.0963185303041792 | 0.000706338764965934 | LUAD | Male-baised eQTL |
| rs9289259 | chr3:125724669:T:C | - | -0.0962958659139165 | 0.000710516955504362 | LUAD | Male-baised eQTL |
| rs2971308 | chr3:125716389:C:T | - | -0.0963014515890751 | 0.000715593916748333 | LUAD | Male-baised eQTL |
| rs2976782 | chr3:125724108:A:C | - | -0.0955471293810395 | 0.000834962835741017 | LUAD | Male-baised eQTL |
| rs2947621 | chr3:125721101:A:G | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2976777 | chr3:125721395:A:G | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2947624 | chr3:125722171:A:C | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2971319 | chr3:125722747:C:T | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2976781 | chr3:125723195:G:C | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2947628 | chr3:125724110:A:T | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2976784 | chr3:125724289:C:T | - | -0.0954920104031214 | 0.000853697268403233 | LUAD | Male-baised eQTL |
| rs2976772 | chr3:125716908:A:G | - | -0.0945110219856918 | 0.000914936626134481 | LUAD | Male-baised eQTL |
| rs13064004 | chr3:125717632:G:T | - | -0.0945110219856918 | 0.000914936626134481 | LUAD | Male-baised eQTL |
| rs9798848 | chr3:125717263:G:A | - | -0.0944000779264337 | 0.000956832975029681 | LUAD | Male-baised eQTL |
| rs1879627 | chr3:125829350:G:A | - | -0.0751337615006474 | 0.0014335231875273 | LUAD | Male-baised eQTL |
| rs2971291 | chr3:125827660:T:C | - | -0.0783519134738967 | 0.00178665458665152 | LUAD | Male-baised eQTL |
| rs787189 | chr3:120312059:T:C | - | 0.073070368541061 | 0.00552278840281603 | LUAD | Male-baised eQTL |
| rs2979929 | chr3:125822489:T:C | - | -0.0858766520998623 | 0.0060394852910254 | LUAD | Male-baised eQTL |
| rs2979931 | chr3:125824129:T:C | - | -0.0801971197989403 | 0.00710581870970684 | LUAD | Male-baised eQTL |
| rs2947690 | chr3:125829069:A:G | - | -0.0847973648864064 | 0.0104525592516833 | LUAD | Male-baised eQTL |
| rs2361697 | chr3:127057201:A:G | - | -0.0791694703689454 | 0.0122268072429783 | LUAD | Male-baised eQTL |
| rs1716856 | chr3:120380237:G:A | - | 0.0725386751474996 | 0.0127143277375223 | LUAD | Male-baised eQTL |
| rs813698 | chr3:120306681:A:G | - | 0.0689784477616011 | 0.0198062557169485 | LUAD | Male-baised eQTL |
| rs4502540 | chr3:125861775:A:G | - | 0.0620090471737673 | 0.0211467295357971 | LUAD | Male-baised eQTL |
| rs11720091 | chr3:125858695:C:T | - | 0.0619330966136756 | 0.0219676374640558 | LUAD | Male-baised eQTL |
| rs2979934 | chr3:125828072:T:C | - | -0.0776074261046031 | 0.0224109198008208 | LUAD | Male-baised eQTL |
| rs1700 | chr3:120395790:C:T | - | 0.0769914980597348 | 0.0227459777589587 | LUAD | Male-baised eQTL |
| rs11706818 | chr3:125860979:G:A | - | 0.0644165245294166 | 0.0232011350470773 | LUAD | Male-baised eQTL |
| rs4465900 | chr3:125861621:G:T | - | 0.0644165245294166 | 0.0232011350470773 | LUAD | Male-baised eQTL |
| rs2979941 | chr3:125831613:A:G | - | -0.0593581810453152 | 0.0263097517052648 | LUAD | Male-baised eQTL |
| rs368526340 | chr3:120378097:G:C | - | 0.0617346275579612 | 0.027765720912268 | LUAD | Male-baised eQTL |
| rs9868566 | chr3:126423050:C:A | - | 0.103708170013563 | 0.027869314710321 | LUAD | Male-baised eQTL |
| rs11711481 | chr3:125910308:G:A | - | 0.093508742456058 | 0.0294976651473716 | LUAD | Male-baised eQTL |
| rs2947692 | chr3:125829726:A:C | - | -0.0590648616647644 | 0.0326490075702697 | LUAD | Male-baised eQTL |
| rs2979938 | chr3:125829758:G:T | - | -0.0590648616647644 | 0.0326490075702697 | LUAD | Male-baised eQTL |
| rs2971244 | chr3:125830112:C:T | - | -0.0590648616647644 | 0.0326490075702697 | LUAD | Male-baised eQTL |
| rs1815022 | chr3:125830326:T:A | - | -0.0590648616647644 | 0.0326490075702697 | LUAD | Male-baised eQTL |
| rs787187 | chr3:120311830:A:G | - | 0.0723359797817708 | 0.0363836349889415 | LUAD | Male-baised eQTL |
| rs787193 | chr3:120313627:C:A | - | 0.0723359797817708 | 0.0363836349889415 | LUAD | Male-baised eQTL |
| rs59319586 | chr3:125918910:G:A | - | 0.0905636137978382 | 0.0376070646090106 | LUAD | Male-baised eQTL |
| rs112649976 | chr3:125923083:C:T | - | 0.0904890755261006 | 0.0381181055964838 | LUAD | Male-baised eQTL |
| rs6793901 | chr3:127057065:A:G | - | -0.0727677523232447 | 0.0398073814071299 | LUAD | Male-baised eQTL |
| rs4426635 | chr3:125821070:T:G | - | -0.0562299168394346 | 0.0425406856625972 | LUAD | Male-baised eQTL |
| rs12492054 | chr3:115536005:G:A | - | 0.0871645602798799 | 0.0427119854627031 | LUAD | Male-baised eQTL |
| rs2979936 | chr3:125828991:G:A | - | -0.0565418752358689 | 0.0438901729488315 | LUAD | Male-baised eQTL |
| rs10048964 | chr3:120349308:G:C | - | 0.070160126325187 | 0.0444480817291626 | LUAD | Male-baised eQTL |
| rs13318758 | chr3:120349385:T:C | - | 0.070160126325187 | 0.0444480817291626 | LUAD | Male-baised eQTL |
| rs9860676 | chr3:120403648:G:T | - | 0.0699373584216782 | 0.0457516593691377 | LUAD | Male-baised eQTL |
| rs2638591 | chr3:120312091:C:G | - | 0.0698798390741411 | 0.0475426192050791 | LUAD | Male-baised eQTL |
| rs787190 | chr3:120312164:G:A | - | 0.0698798390741411 | 0.0475426192050791 | LUAD | Male-baised eQTL |
| rs787192 | chr3:120312806:T:G | - | 0.0698798390741411 | 0.0475426192050791 | LUAD | Male-baised eQTL |
| rs1085614 | chr3:120315705:C:T | - | 0.0698798390741411 | 0.0475426192050791 | LUAD | Male-baised eQTL |
| rs1085616 | chr3:120317262:G:A | - | 0.0698798390741411 | 0.0475426192050791 | LUAD | Male-baised eQTL |
| rs2971245 | chr3:125831772:A:C | - | -0.0555028388293429 | 0.048673310019846 | LUAD | Male-baised eQTL |
| rs2979942 | chr3:125831967:C:T | - | -0.0555028388293429 | 0.048673310019846 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000114638 |
| CpG Site: cg01814130 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.450784842150983 | |
 | Gene ID: ENSG00000114638 |
| CpG Site: cg02741226 | |
| Position to Gene: promoter | |
| Male Effect: -0.148909505752036 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg02741226 | chr3:119173458 | promoter | -0.148909505752036 | 3.14128308607595e-06 | -0.3542475735853871 | 6.643236583606473e-08 | STAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01814130 | chr3:119173483 | promoter | -0.450784842150983 | 1.28793577629562e-25 | -0.6286172194929742 | 1.8904039703216194e-29 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of UPK1B |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000114638 | UPK1B | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| ENSG00000114638 | UPK1B | C0678222 | Breast Carcinoma | 1 | CTD_human |
| ENSG00000114638 | UPK1B | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| ENSG00000114638 | UPK1B | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| ENSG00000114638 | UPK1B | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
