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Gene: ENSG00000112769 |
Summary for LAMA4 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000112769 | Gene symbol | LAMA4 |
| Gene name | laminin subunit alpha 4 | |
| HGNC | 6484 | |
| Entrez ID | 3910 | |
| Gene type | protein_coding | |
| Synonyms | LAMA4|LAMA3 | |
| UniProtAcc | Q16363 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000112769 | LAMA3 | DB06245 | Lanoteplase | BiotechDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for LAMA4 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LAMA4 | 3.44e+03 | -2.10e+00 | 3.89e-01 | -5.42e+00 | 6.07e-08 | 6.45e-07 | BLCA |
| LAMA4 | 1.48e+03 | 1.34e+00 | 5.67e-01 | 2.36e+00 | 1.83e-02 | 4.15e-02 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LAMA4 | 3.26e+03 | 1.65e+00 | 2.82e-01 | 5.84e+00 | 5.24e-09 | 1.11e-07 | HNSC |
| LAMA4 | 7.23e+03 | -1.51e+00 | 8.72e-02 | -1.73e+01 | 2.01e-67 | 3.27e-66 | BRCA |
Top |
Sex-biased somatic mutation for LAMA4 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for LAMA4 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg14289461 | chr6:112254727 | CGI:chr6:112253889-112254281 | promoter,gene body | 4.58e-01 | 2.98e-01 | 2.53e+00 | 1.15e-02 | 2.82e-02 | 1.61e-01 |
| BRCA | cg13938098 | chr6:112254764 | CGI:chr6:112253889-112254281 | promoter,gene body | 3.87e-01 | 2.66e-01 | 2.51e+00 | 1.20e-02 | 2.86e-02 | 1.20e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg11934419 | chr6:112254648 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 3.77e-01 | 4.90e-01 | -3.11e+00 | 1.85e-03 | 2.67e-03 | -1.13e-01 |
| KIRC | cg10910512 | chr6:112254807 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 5.87e-01 | 7.67e-01 | -2.07e+00 | 3.81e-02 | 3.92e-02 | -1.80e-01 |
| KIRC | cg08844365 | chr6:112255191 | CGI:chr6:112253889-112254281 | promoter | 7.54e-01 | 8.74e-01 | -4.67e+00 | 3.00e-06 | 9.46e-06 | -1.20e-01 |
| LUSC | cg08897388 | chr6:112254503 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 3.39e-01 | 2.06e-01 | 2.44e+00 | 1.47e-02 | 1.87e-02 | 1.33e-01 |
| LUSC | cg11934419 | chr6:112254648 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 5.34e-01 | 4.29e-01 | 2.07e+00 | 3.87e-02 | 4.05e-02 | 1.05e-01 |
| LUSC | cg14289461 | chr6:112254727 | CGI:chr6:112253889-112254281 | promoter,gene body | 5.35e-01 | 3.39e-01 | 2.93e+00 | 3.44e-03 | 6.19e-03 | 1.96e-01 |
| LUSC | cg13938098 | chr6:112254764 | CGI:chr6:112253889-112254281 | promoter,gene body | 4.77e-01 | 3.14e-01 | 3.01e+00 | 2.65e-03 | 5.12e-03 | 1.63e-01 |
| LUSC | cg10910512 | chr6:112254807 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 6.73e-01 | 5.35e-01 | 2.55e+00 | 1.07e-02 | 1.46e-02 | 1.37e-01 |
| LUSC | cg07628084 | chr6:112254917 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 7.28e-01 | 5.51e-01 | 3.33e+00 | 8.83e-04 | 2.39e-03 | 1.77e-01 |
| COAD | cg09105802 | chr6:112254028 | CGI:chr6:112253889-112254281 | promoter,exon,CDS,gene body | 2.42e-01 | 4.23e-02 | 2.17e+00 | 2.99e-02 | 3.37e-02 | 2.00e-01 |
| COAD | cg01254555 | chr6:112254010 | CGI:chr6:112253889-112254281 | promoter,exon,CDS,gene body | 2.53e-01 | 5.76e-02 | 2.82e+00 | 4.74e-03 | 7.91e-03 | 1.96e-01 |
| COAD | cg11934419 | chr6:112254648 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 4.55e-01 | 3.20e-01 | 2.57e+00 | 1.02e-02 | 1.45e-02 | 1.35e-01 |
| BLCA | cg11934419 | chr6:112254648 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 4.28e-01 | 3.10e-01 | 2.33e+00 | 1.96e-02 | 2.41e-02 | 1.18e-01 |
| BLCA | cg10910512 | chr6:112254807 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 4.66e-01 | 2.98e-01 | 2.62e+00 | 8.77e-03 | 1.27e-02 | 1.68e-01 |
| BLCA | cg07628084 | chr6:112254917 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 6.56e-01 | 4.73e-01 | 3.18e+00 | 1.49e-03 | 3.11e-03 | 1.83e-01 |
| BLCA | cg18080303 | chr6:112255140 | CGI:chr6:112253889-112254281 | promoter | 8.11e-01 | 6.68e-01 | 3.24e+00 | 1.20e-03 | 2.62e-03 | 1.43e-01 |
| ESCA | cg11934419 | chr6:112254648 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 5.81e-01 | 4.01e-01 | 2.65e+00 | 8.04e-03 | 3.55e-02 | 1.80e-01 |
| ESCA | cg14289461 | chr6:112254727 | CGI:chr6:112253889-112254281 | promoter,gene body | 4.83e-01 | 2.40e-01 | 2.70e+00 | 6.93e-03 | 3.53e-02 | 2.43e-01 |
| ESCA | cg13938098 | chr6:112254764 | CGI:chr6:112253889-112254281 | promoter,gene body | 4.35e-01 | 2.54e-01 | 2.60e+00 | 9.30e-03 | 3.58e-02 | 1.81e-01 |
| ESCA | cg10910512 | chr6:112254807 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 6.66e-01 | 3.52e-01 | 3.42e+00 | 6.15e-04 | 3.37e-02 | 3.14e-01 |
| ESCA | cg18080303 | chr6:112255140 | CGI:chr6:112253889-112254281 | promoter | 7.62e-01 | 5.89e-01 | 2.31e+00 | 2.07e-02 | 4.06e-02 | 1.73e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg08897388 | chr6:112254503 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 3.41e-01 | 1.41e-01 | 9.98e+00 | 1.79e-23 | 1.32e-22 | 2.00e-01 |
| BRCA | cg11934419 | chr6:112254648 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 5.99e-01 | 2.74e-01 | 1.33e+01 | 3.94e-40 | 3.21e-38 | 3.25e-01 |
| BRCA | cg14289461 | chr6:112254727 | CGI:chr6:112253889-112254281 | promoter,gene body | 4.58e-01 | 1.90e-01 | 1.23e+01 | 9.80e-35 | 2.76e-33 | 2.68e-01 |
| BRCA | cg13938098 | chr6:112254764 | CGI:chr6:112253889-112254281 | promoter,gene body | 3.87e-01 | 2.29e-01 | 1.05e+01 | 9.71e-26 | 8.86e-25 | 1.58e-01 |
| BRCA | cg10910512 | chr6:112254807 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 6.18e-01 | 4.06e-01 | 2.20e+00 | 2.81e-02 | 2.94e-02 | 2.12e-01 |
| BRCA | cg07628084 | chr6:112254917 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 7.37e-01 | 4.70e-01 | 1.20e+01 | 2.96e-33 | 6.64e-32 | 2.67e-01 |
| BRCA | cg18080303 | chr6:112255140 | CGI:chr6:112253889-112254281 | promoter | 8.15e-01 | 6.58e-01 | 1.09e+01 | 8.25e-28 | 9.31e-27 | 1.57e-01 |
| BRCA | cg08844365 | chr6:112255191 | CGI:chr6:112253889-112254281 | promoter | 8.13e-01 | 6.45e-01 | 1.10e+01 | 3.45e-28 | 4.06e-27 | 1.69e-01 |
| LUAD | cg18080303 | chr6:112255140 | CGI:chr6:112253889-112254281 | promoter | 8.10e-01 | 6.53e-01 | 4.00e+00 | 6.41e-05 | 7.37e-04 | 1.57e-01 |
| LUAD | cg08844365 | chr6:112255191 | CGI:chr6:112253889-112254281 | promoter | 7.78e-01 | 6.55e-01 | 3.34e+00 | 8.23e-04 | 2.81e-03 | 1.23e-01 |
| COAD | cg18080303 | chr6:112255140 | CGI:chr6:112253889-112254281 | promoter | 6.61e-01 | 8.08e-01 | -2.90e+00 | 3.69e-03 | 7.62e-03 | -1.47e-01 |
| COAD | cg08844365 | chr6:112255191 | CGI:chr6:112253889-112254281 | promoter | 5.48e-01 | 6.69e-01 | -2.51e+00 | 1.22e-02 | 1.82e-02 | -1.21e-01 |
| LIHC | cg08897388 | chr6:112254503 | CGI:chr6:112253889-112254281 | UTR,promoter,exon,gene body | 4.41e-01 | 3.00e-01 | 2.13e+00 | 3.34e-02 | 3.63e-02 | 1.41e-01 |
Top |
Exon skipping events with PSI in TCGA for LAMA4 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for LAMA4 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| STAD | LAMA4-008 | chr6_112168431_- | 3.04e-01 | 1.88e-01 | 2.33e+00 | 1.96e-02 | 4.96e-02 | 1.15e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for LAMA4 |
| TFs related to LAMA4. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SARC | SRY | LAMA4 | 4.44e+00 | 9.83e-01 | 3.87e+00 | 9.27e-03 | Male-biased |
| SKCM | ZNF418 | LAMA4 | 3.38e+00 | 4.17e-03 | 4.64e+00 | 9.85e-01 | Female-biased |
| LAMA4 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for LAMA4 |
| RBPs related to ES in LAMA4. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LUAD | HNRNPA2B1 | exon_skip_461955 | 1.20e+01 | 2.00e-03 | 1.26e+01 | 9.98e-01 | Female-biased |
| ESCA | HNRNPA2B1 | exon_skip_461955 | 1.17e+01 | 1.12e-02 | 1.22e+01 | 9.88e-01 | Female-biased |
| READ | SRSF7 | exon_skip_461957 | 9.57e+00 | 9.21e-03 | 9.92e+00 | 9.89e-01 | Female-biased |
| THCA | RBM41 | exon_skip_461953 | 8.53e+00 | 9.84e-01 | 8.24e+00 | 1.02e-02 | Male-biased |
| THCA | RBMS1 | exon_skip_461953 | 1.10e+01 | 9.95e-01 | 1.07e+01 | 4.37e-03 | Male-biased |
| GBM | HNRNPA2B1 | exon_skip_461955 | 1.18e+01 | 1.38e-03 | 1.24e+01 | 9.98e-01 | Female-biased |
| LAMA4 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000112769 | AL138995.1,hsa-mir-152,LAMA4 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000112769 | AC105942.1,hsa-mir-152,LAMA4 | Male-specific ceRNA | TCGA-BLCA |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12526522 | chr6:118120518:C:T | - | 0.195491719201126 | 0.0462475864163092 | READ | Female-baised eQTL |
| rs79677950 | chr6:118117304:G:A | - | 0.195148810325074 | 0.0480384590584385 | READ | Female-baised eQTL |
| rs9400210 | chr6:108153731:T:C | - | 0.269820022841527 | 0.0417097137419743 | GBM | Female-baised eQTL |
| rs882073 | chr6:109290555:G:A | - | 0.225708509535827 | 0.0449081409505106 | GBM | Female-baised eQTL |
| rs1883973 | chr6:113180869:A:G | - | -0.184313693632343 | 0.0480563352618884 | GBM | Female-baised eQTL |
| rs60819933 | chr6:109288257:T:C | - | 0.223399344564329 | 0.0491292529689897 | GBM | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12524181 | chr6:121414915:G:T | - | 0.153573917155166 | 0.000190622638903256 | LGG | Male-baised eQTL |
| rs2207959 | chr6:106450200:G:C | - | 0.0585059881982739 | 0.026472757692798 | LUAD | Male-baised eQTL |
| rs72943025 | chr6:106562971:G:C | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs115132229 | chr6:106565030:G:C | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs72943042 | chr6:106569463:T:G | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs41312800 | chr6:106569836:T:C | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs41292422 | chr6:106571287:A:G | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs72943087 | chr6:106581283:G:A | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs72943092 | chr6:106584253:T:G | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs75644932 | chr6:106584543:T:C | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs72943097 | chr6:106585549:G:A | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs72945008 | chr6:106588829:G:C | - | 0.125359629603782 | 0.000691921750041297 | COAD | Male-baised eQTL |
| rs76080904 | chr6:106553156:C:G | - | 0.126249145948281 | 0.00071925886389138 | COAD | Male-baised eQTL |
| rs55904932 | chr6:106576695:G:A | - | 0.106329365931428 | 0.000764374141986666 | COAD | Male-baised eQTL |
| rs142034044 | chr6:106601692:C:G | - | 0.121612362228424 | 0.00106717088110363 | COAD | Male-baised eQTL |
| rs72945045 | chr6:106603482:C:T | - | 0.121612362228424 | 0.00106717088110363 | COAD | Male-baised eQTL |
| rs72945047 | chr6:106606867:A:C | - | 0.121612362228424 | 0.00106717088110363 | COAD | Male-baised eQTL |
| rs72945056 | chr6:106612016:C:A | - | 0.121612362228424 | 0.00106717088110363 | COAD | Male-baised eQTL |
| rs2618359 | chr6:120176426:T:A | - | 0.0691525592771191 | 0.00113384594134098 | COAD | Male-baised eQTL |
| rs6931333 | chr6:117721642:C:A | - | 0.139853540950207 | 0.00120833539393113 | COAD | Male-baised eQTL |
| rs72945075 | chr6:106621576:T:G | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs72945079 | chr6:106623760:T:C | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs72945081 | chr6:106623767:G:A | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs72945093 | chr6:106631255:T:C | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs72945095 | chr6:106631488:T:C | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs67928503 | chr6:106631672:A:T | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs72945097 | chr6:106632822:T:G | - | 0.131729607463922 | 0.00225215784437262 | COAD | Male-baised eQTL |
| rs72941373 | chr6:106546154:T:C | - | 0.11305135062368 | 0.00256032113566514 | COAD | Male-baised eQTL |
| rs146656921 | chr6:106548990:G:A | - | 0.112657955256872 | 0.00271591139667685 | COAD | Male-baised eQTL |
| rs61741114 | chr6:106543486:T:C | - | 0.110307346577871 | 0.00337362312790737 | COAD | Male-baised eQTL |
| rs72941326 | chr6:106535606:C:T | - | 0.109894819633599 | 0.00361555421970862 | COAD | Male-baised eQTL |
| rs12525311 | chr6:106578555:A:G | - | 0.103259262451477 | 0.00600497156278581 | COAD | Male-baised eQTL |
| rs17067395 | chr6:106582304:A:G | - | 0.103259262451477 | 0.00600497156278581 | COAD | Male-baised eQTL |
| rs12528136 | chr6:106587576:C:T | - | 0.103259262451477 | 0.00600497156278581 | COAD | Male-baised eQTL |
| rs72945007 | chr6:106588771:A:G | - | 0.103259262451477 | 0.00600497156278581 | COAD | Male-baised eQTL |
| rs72945040 | chr6:106601401:A:G | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs72945046 | chr6:106604665:A:C | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs58620450 | chr6:106608651:T:C | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs72945053 | chr6:106609392:G:A | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs74425787 | chr6:106610342:G:A | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs77166881 | chr6:106611582:T:C | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs80183145 | chr6:106612272:A:C | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs72945059 | chr6:106612933:T:A | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs59962977 | chr6:106613455:C:T | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs12529961 | chr6:106613756:A:C | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs17067443 | chr6:106614312:T:C | - | 0.100453770141915 | 0.00806104480287509 | COAD | Male-baised eQTL |
| rs12526024 | chr6:106602315:G:A | - | 0.100464949489325 | 0.00809393071728538 | COAD | Male-baised eQTL |
| rs9386573 | chr6:106611596:C:G | - | 0.10024382185225 | 0.00834472928373532 | COAD | Male-baised eQTL |
| rs803526 | chr6:106390317:C:T | - | 0.0580185225762533 | 0.0087498162533542 | COAD | Male-baised eQTL |
| rs803523 | chr6:106391846:G:A | - | 0.0573163749199596 | 0.00935401575653184 | COAD | Male-baised eQTL |
| rs1478810 | chr6:120332315:G:A | - | -0.059308883706637 | 0.0100689979062926 | COAD | Male-baised eQTL |
| rs12192030 | chr6:120334397:T:C | - | -0.0606148948303551 | 0.010645809955832 | COAD | Male-baised eQTL |
| rs1676030 | chr6:106549725:T:C | - | 0.10080176279971 | 0.0111410015320428 | COAD | Male-baised eQTL |
| rs803525 | chr6:106391037:C:T | - | 0.0583216666369727 | 0.0112696793272577 | COAD | Male-baised eQTL |
| rs9374096 | chr6:109548281:A:G | - | -0.0643445122643361 | 0.0124061552035235 | COAD | Male-baised eQTL |
| rs1925921 | chr6:109525825:T:C | - | -0.0643251748699185 | 0.0124517907621206 | COAD | Male-baised eQTL |
| rs4946982 | chr6:109526113:A:C | - | -0.0643251748699185 | 0.0124517907621206 | COAD | Male-baised eQTL |
| rs7775420 | chr6:109534567:A:G | - | -0.064164281367518 | 0.0127041908139736 | COAD | Male-baised eQTL |
| rs9374093 | chr6:109535932:C:T | - | -0.064164281367518 | 0.0127041908139736 | COAD | Male-baised eQTL |
| rs9386814 | chr6:109556737:G:T | - | -0.0640203252867725 | 0.0131714982996955 | COAD | Male-baised eQTL |
| rs2064822 | chr6:109544487:G:T | - | -0.0640884036999398 | 0.0132798658110736 | COAD | Male-baised eQTL |
| rs6938741 | chr6:109552074:G:T | - | -0.0640884036999398 | 0.0132798658110736 | COAD | Male-baised eQTL |
| rs2787523 | chr6:106388336:T:C | - | 0.0555136702446693 | 0.0145942443812564 | COAD | Male-baised eQTL |
| rs2749084 | chr6:106388347:C:A | - | 0.0555136702446693 | 0.0145942443812564 | COAD | Male-baised eQTL |
| rs3013696 | chr6:120336732:T:G | - | -0.056365912063572 | 0.0164847862565677 | COAD | Male-baised eQTL |
| rs9486917 | chr6:108695835:C:T | - | 0.0811937632266177 | 0.0172951256172861 | COAD | Male-baised eQTL |
| rs72945067 | chr6:106616046:G:A | - | 0.117792564273114 | 0.0179735583597494 | COAD | Male-baised eQTL |
| rs72945068 | chr6:106617738:C:T | - | 0.117792564273114 | 0.0179735583597494 | COAD | Male-baised eQTL |
| rs72945071 | chr6:106618624:G:A | - | 0.117792564273114 | 0.0179735583597494 | COAD | Male-baised eQTL |
| rs72945072 | chr6:106618668:G:T | - | 0.117792564273114 | 0.0179735583597494 | COAD | Male-baised eQTL |
| rs17067428 | chr6:106603680:T:G | - | 0.0910046169147625 | 0.0180473447969157 | COAD | Male-baised eQTL |
| rs9320300 | chr6:109566522:C:T | - | -0.0616482961681854 | 0.0188307520042466 | COAD | Male-baised eQTL |
| rs2357127 | chr6:109579240:T:C | - | -0.0616482961681854 | 0.0188307520042466 | COAD | Male-baised eQTL |
| rs6568583 | chr6:109590644:T:G | - | -0.0616482961681854 | 0.0188307520042466 | COAD | Male-baised eQTL |
| rs12200787 | chr6:109598122:C:G | - | -0.0616482961681854 | 0.0188307520042466 | COAD | Male-baised eQTL |
| rs6925886 | chr6:109557312:A:G | - | -0.0621020881423185 | 0.0194497463603195 | COAD | Male-baised eQTL |
| rs9320114 | chr6:105397539:T:G | - | 0.0696499411868902 | 0.0207365599693472 | COAD | Male-baised eQTL |
| rs6568582 | chr6:109560528:G:T | - | -0.0609286668425015 | 0.0210210565025671 | COAD | Male-baised eQTL |
| rs1385960 | chr6:120448304:G:C | - | 0.0561421556208943 | 0.0212661290823646 | COAD | Male-baised eQTL |
| rs9400300 | chr6:109561395:A:T | - | -0.0607050057395778 | 0.0216861328951149 | COAD | Male-baised eQTL |
| rs1619049 | chr6:118719563:T:C | - | -0.0937581913635684 | 0.0244486849462201 | COAD | Male-baised eQTL |
| rs803527 | chr6:106389828:T:A | - | 0.0528138343485908 | 0.0260186971645903 | COAD | Male-baised eQTL |
| rs12525732 | chr6:105871686:C:T | - | 0.097934999536622 | 0.0260646038843226 | COAD | Male-baised eQTL |
| rs803594 | chr6:117258422:C:G | - | 0.0578294206641273 | 0.0269216611614904 | COAD | Male-baised eQTL |
| rs9400289 | chr6:109526789:G:A | - | -0.0586178544650732 | 0.0298139515079651 | COAD | Male-baised eQTL |
| rs11961564 | chr6:114653813:G:A | - | 0.0984961449043791 | 0.0302679071343582 | COAD | Male-baised eQTL |
| rs13215565 | chr6:103782732:G:C | - | 0.0961198158386986 | 0.0303582376247261 | COAD | Male-baised eQTL |
| rs9481850 | chr6:118701790:C:A | - | 0.0523786455993299 | 0.032359132358746 | COAD | Male-baised eQTL |
| rs4947006 | chr6:109660230:T:C | - | -0.057713076235299 | 0.0335613481216335 | COAD | Male-baised eQTL |
| rs911023 | chr6:109661426:T:C | - | -0.057713076235299 | 0.0335613481216335 | COAD | Male-baised eQTL |
| rs1843597 | chr6:120444126:G:A | - | 0.052686057091214 | 0.0336983834320698 | COAD | Male-baised eQTL |
| rs2787522 | chr6:106388330:T:G | - | 0.0518425778148043 | 0.0345626528838075 | COAD | Male-baised eQTL |
| rs4947004 | chr6:109659114:G:A | - | -0.0574694067280942 | 0.03459724966671 | COAD | Male-baised eQTL |
| rs6568591 | chr6:109671681:C:T | - | -0.0574694067280942 | 0.03459724966671 | COAD | Male-baised eQTL |
| rs829817 | chr6:109677082:C:T | - | 0.0574694067280942 | 0.03459724966671 | COAD | Male-baised eQTL |
| rs2357962 | chr6:120441058:A:G | - | 0.052773497424745 | 0.0346325261958916 | COAD | Male-baised eQTL |
| rs10872203 | chr6:120441698:A:C | - | 0.052773497424745 | 0.0346325261958916 | COAD | Male-baised eQTL |
| rs9400396 | chr6:110516085:C:A | - | 0.0551900277134355 | 0.0358957937783448 | COAD | Male-baised eQTL |
| rs9320294 | chr6:109540646:C:A | - | -0.0532013441221689 | 0.0361282440244716 | COAD | Male-baised eQTL |
| rs9320295 | chr6:109540669:A:C | - | -0.0532013441221689 | 0.0361282440244716 | COAD | Male-baised eQTL |
| rs9320296 | chr6:109540683:C:T | - | -0.0532013441221689 | 0.0361282440244716 | COAD | Male-baised eQTL |
| rs7744119 | chr6:110514458:C:T | - | 0.055049580498023 | 0.0365936618931903 | COAD | Male-baised eQTL |
| rs11153242 | chr6:110513079:G:C | - | 0.0549196264611788 | 0.0372378065341466 | COAD | Male-baised eQTL |
| rs9384710 | chr6:109534980:A:C | - | -0.0525589536004989 | 0.0374417254287719 | COAD | Male-baised eQTL |
| rs9487139 | chr6:109540371:T:C | - | -0.0525589536004989 | 0.0374417254287719 | COAD | Male-baised eQTL |
| rs147749169 | chr6:120464403:C:T | - | 0.0528192694277404 | 0.0385052036180658 | COAD | Male-baised eQTL |
| rs942924 | chr6:109531853:C:T | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs1998812 | chr6:109531868:C:T | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs942923 | chr6:109532243:A:G | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs6916239 | chr6:109534252:T:A | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs7450225 | chr6:109536119:A:G | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs143472212 | chr6:109537195:C:G | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs4946984 | chr6:109538964:C:T | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs9398204 | chr6:109539969:A:G | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs9487138 | chr6:109540342:T:C | - | -0.0523947428093304 | 0.0390648935544694 | COAD | Male-baised eQTL |
| rs9385137 | chr6:120439984:G:A | - | 0.053014736079519 | 0.0394750834692547 | COAD | Male-baised eQTL |
| rs4496833 | chr6:120440918:C:G | - | 0.053014736079519 | 0.0394750834692547 | COAD | Male-baised eQTL |
| rs2357961 | chr6:120441040:A:T | - | 0.053014736079519 | 0.0394750834692547 | COAD | Male-baised eQTL |
| rs7740594 | chr6:120450867:A:G | - | 0.0516696651822025 | 0.0396380471360341 | COAD | Male-baised eQTL |
| rs6569124 | chr6:120451467:C:T | - | 0.0516696651822025 | 0.0396380471360341 | COAD | Male-baised eQTL |
| rs6937633 | chr6:120454922:C:T | - | 0.0516696651822025 | 0.0396380471360341 | COAD | Male-baised eQTL |
| rs9372220 | chr6:109625022:T:C | - | -0.0569809480170046 | 0.0396437829362056 | COAD | Male-baised eQTL |
| rs6921303 | chr6:109631530:G:A | - | -0.0569809480170046 | 0.0396437829362056 | COAD | Male-baised eQTL |
| rs4946995 | chr6:109640165:C:T | - | -0.0569809480170046 | 0.0396437829362056 | COAD | Male-baised eQTL |
| rs4946998 | chr6:109640302:T:C | - | -0.0569809480170046 | 0.0396437829362056 | COAD | Male-baised eQTL |
| rs7772625 | chr6:109647064:C:T | - | -0.0569809480170046 | 0.0396437829362056 | COAD | Male-baised eQTL |
| rs6569125 | chr6:120454443:G:A | - | 0.0516356433109207 | 0.0398868616885595 | COAD | Male-baised eQTL |
| rs6922962 | chr6:110406455:C:T | - | -0.094585258894808 | 0.0405321965392536 | COAD | Male-baised eQTL |
| rs6932774 | chr6:109616198:G:A | - | -0.056738529238196 | 0.0408302668784174 | COAD | Male-baised eQTL |
| rs4946997 | chr6:109640267:T:C | - | -0.056738529238196 | 0.0408302668784174 | COAD | Male-baised eQTL |
| rs4947002 | chr6:109648588:C:G | - | -0.056738529238196 | 0.0408302668784174 | COAD | Male-baised eQTL |
| rs12175381 | chr6:110512816:G:C | - | 0.0547800570590469 | 0.0416490623116414 | COAD | Male-baised eQTL |
| rs9385144 | chr6:120462316:T:C | - | 0.0517658067717135 | 0.0417224080723409 | COAD | Male-baised eQTL |
| rs9387775 | chr6:120462630:T:C | - | 0.0517658067717135 | 0.0417224080723409 | COAD | Male-baised eQTL |
| rs9387777 | chr6:120463002:T:A | - | 0.0517268578720758 | 0.0420059286301885 | COAD | Male-baised eQTL |
| rs7453405 | chr6:109650894:C:T | - | -0.0565903793697493 | 0.0425490072943205 | COAD | Male-baised eQTL |
| rs11153244 | chr6:110525638:T:C | - | 0.0536675689305604 | 0.0426681136886481 | COAD | Male-baised eQTL |
| rs7766766 | chr6:109541559:T:C | - | -0.0518441374641926 | 0.0429536921586225 | COAD | Male-baised eQTL |
| rs11754263 | chr6:109713052:C:T | - | 0.05664782937697 | 0.0437121458418052 | COAD | Male-baised eQTL |
| rs61170920 | chr6:109707293:G:A | - | 0.0565756575909914 | 0.0447510553273231 | COAD | Male-baised eQTL |
| rs9398563 | chr6:120451964:T:C | - | 0.0519047177190281 | 0.0449338085858995 | COAD | Male-baised eQTL |
| rs2357963 | chr6:120453084:C:G | - | 0.0519047177190281 | 0.0449338085858995 | COAD | Male-baised eQTL |
| rs2357964 | chr6:120453085:T:G | - | 0.0519047177190281 | 0.0449338085858995 | COAD | Male-baised eQTL |
| rs2357965 | chr6:120453086:C:A | - | 0.0519047177190281 | 0.0449338085858995 | COAD | Male-baised eQTL |
| rs6900187 | chr6:109711201:C:T | - | 0.0564032691621684 | 0.0450145371637132 | COAD | Male-baised eQTL |
| rs3013713 | chr6:120373413:G:A | - | -0.0509708551085808 | 0.0452207594647643 | COAD | Male-baised eQTL |
| rs12212255 | chr6:112834165:C:T | - | 0.0776937838868471 | 0.0468795968003123 | COAD | Male-baised eQTL |
| rs2798326 | chr6:118684063:C:T | - | 0.0497993565330988 | 0.0473913246438044 | COAD | Male-baised eQTL |
| rs7765922 | chr6:120460781:A:T | - | 0.0519754688092174 | 0.0475352868317992 | COAD | Male-baised eQTL |
| rs9385141 | chr6:120455331:A:G | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs9374912 | chr6:120455568:G:T | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs1021249 | chr6:120456108:C:T | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs9320751 | chr6:120457097:C:T | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs4291122 | chr6:120459064:C:G | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs9320752 | chr6:120459786:T:C | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs9320753 | chr6:120460038:G:C | - | 0.0507231758629958 | 0.0482897036453582 | COAD | Male-baised eQTL |
| rs56125306 | chr6:109703263:A:G | - | 0.0559505192514271 | 0.0489868776104068 | COAD | Male-baised eQTL |
| rs1857312 | chr6:118680363:A:C | - | 0.0496322084026338 | 0.0490627506515086 | COAD | Male-baised eQTL |
| rs6917300 | chr6:109713636:C:T | - | 0.0552992370238837 | 0.049382359790815 | COAD | Male-baised eQTL |
| rs6924436 | chr6:109715276:A:T | - | 0.0552992370238837 | 0.049382359790815 | COAD | Male-baised eQTL |
| rs56264193 | chr6:109706873:G:C | - | 0.0557232361209534 | 0.0494230243915667 | COAD | Male-baised eQTL |
| rs6900133 | chr6:109711025:G:C | - | 0.0557232361209534 | 0.0494230243915667 | COAD | Male-baised eQTL |
| rs2638550 | chr6:118677318:C:G | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs2638551 | chr6:118677593:T:C | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs2638552 | chr6:118678249:C:T | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs9489497 | chr6:118678473:T:C | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs2638545 | chr6:118679040:G:C | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs902779 | chr6:118679430:T:G | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs1343287 | chr6:118680642:T:C | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs2638544 | chr6:118680815:G:A | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| rs1844964 | chr6:118681365:C:T | - | 0.0495856731621731 | 0.0494289397330218 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of LAMA4 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000112769 | LAMA4 | C0000786 | Spontaneous abortion | 1 | CTD_human |
| ENSG00000112769 | LAMA4 | C0000822 | Abortion, Tubal | 1 | CTD_human |
| ENSG00000112769 | LAMA4 | C3808935 | CARDIOMYOPATHY, DILATED, 1JJ | 1 | CTD_human |
| ENSG00000112769 | LAMA4 | C3830362 | Early Pregnancy Loss | 1 | CTD_human |
| ENSG00000112769 | LAMA4 | C4552766 | Miscarriage | 1 | CTD_human |
