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Gene: ENSG00000112655 |
Summary for PTK7 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000112655 | Gene symbol | PTK7 |
| Gene name | protein tyrosine kinase 7 (inactive) | |
| HGNC | 9618 | |
| Entrez ID | 5754 | |
| Gene type | protein_coding | |
| Synonyms | PTK7|CCK4 | |
| UniProtAcc | Q13308 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PTK7 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PTK7 | 1.12e+04 | 1.91e+00 | 3.86e-01 | 4.95e+00 | 7.44e-07 | 1.88e-05 | ESCA |
| PTK7 | 1.93e+03 | 3.18e+00 | 6.10e-01 | 5.21e+00 | 1.88e-07 | 1.58e-06 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PTK7 | 6.39e+03 | 1.10e+00 | 2.80e-01 | 3.91e+00 | 9.07e-05 | 1.28e-03 | BLCA |
| PTK7 | 3.37e+03 | 2.18e+00 | 3.78e-01 | 5.78e+00 | 7.33e-09 | 1.21e-07 | READ |
Top |
Sex-biased somatic mutation for PTK7 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for PTK7 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg15123159 | chr6:43077948 | CGI:chr6:43076196-43077319 | promoter,gene body | 6.20e-01 | 7.24e-01 | -2.57e+00 | 1.03e-02 | 2.70e-02 | -1.04e-01 |
| LIHC | cg25998680 | chr6:43076501 | CGI:chr6:43076196-43077319 | promoter,exon,CDS,gene body | 2.68e-01 | 4.02e-01 | -3.97e+00 | 7.17e-05 | 5.48e-04 | -1.34e-01 |
| LIHC | cg08747889 | chr6:43076048 | CGI:chr6:43076196-43077319 | promoter | 3.62e-01 | 4.94e-01 | -4.92e+00 | 8.55e-07 | 1.19e-05 | -1.32e-01 |
| LIHC | cg00252032 | chr6:43076077 | CGI:chr6:43076196-43077319 | promoter | 2.91e-01 | 4.23e-01 | -5.01e+00 | 5.52e-07 | 7.93e-06 | -1.31e-01 |
| LIHC | cg25207447 | chr6:43076093 | CGI:chr6:43076196-43077319 | promoter | 3.19e-01 | 4.44e-01 | -4.83e+00 | 1.34e-06 | 1.81e-05 | -1.25e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| COAD | cg00252032 | chr6:43076077 | CGI:chr6:43076196-43077319 | promoter | 1.84e-01 | 7.92e-02 | 2.88e+00 | 3.92e-03 | 6.79e-03 | 1.05e-01 |
| BLCA | cg02057561 | chr6:43075953 | CGI:chr6:43076196-43077319 | promoter | 6.98e-01 | 5.92e-01 | 2.62e+00 | 8.77e-03 | 1.27e-02 | 1.06e-01 |
| LIHC | cg21663580 | chr6:43077033 | CGI:chr6:43076196-43077319 | promoter,gene body | 6.43e-01 | 5.40e-01 | 4.73e+00 | 2.25e-06 | 7.46e-06 | 1.03e-01 |
| LIHC | cg08747889 | chr6:43076048 | CGI:chr6:43076196-43077319 | promoter | 4.94e-01 | 3.71e-01 | 2.53e+00 | 1.16e-02 | 1.38e-02 | 1.23e-01 |
| LIHC | cg00252032 | chr6:43076077 | CGI:chr6:43076196-43077319 | promoter | 4.23e-01 | 2.81e-01 | 2.73e+00 | 6.34e-03 | 8.13e-03 | 1.41e-01 |
| LIHC | cg25207447 | chr6:43076093 | CGI:chr6:43076196-43077319 | promoter | 4.44e-01 | 2.73e-01 | 3.09e+00 | 1.98e-03 | 2.91e-03 | 1.71e-01 |
| KIRP | cg02057561 | chr6:43075953 | CGI:chr6:43076196-43077319 | promoter | 8.61e-01 | 7.60e-01 | 5.27e+00 | 1.37e-07 | 1.08e-06 | 1.01e-01 |
| CHOL | cg25998680 | chr6:43076501 | CGI:chr6:43076196-43077319 | promoter,exon,CDS,gene body | 6.86e-02 | 4.03e-01 | -3.39e+00 | 6.96e-04 | 9.20e-03 | -3.35e-01 |
| CHOL | cg21663580 | chr6:43077033 | CGI:chr6:43076196-43077319 | promoter,gene body | 1.52e-01 | 6.13e-01 | -3.17e+00 | 1.52e-03 | 1.07e-02 | -4.61e-01 |
| CHOL | cg08747889 | chr6:43076048 | CGI:chr6:43076196-43077319 | promoter | 2.54e-01 | 3.99e-01 | -1.99e+00 | 4.65e-02 | 4.65e-02 | -1.44e-01 |
| CHOL | cg00252032 | chr6:43076077 | CGI:chr6:43076196-43077319 | promoter | 1.40e-01 | 2.92e-01 | -2.65e+00 | 7.96e-03 | 1.92e-02 | -1.51e-01 |
| CHOL | cg09332655 | chr6:43076799 | CGI:chr6:43076196-43077319 | promoter,gene body | 1.30e-01 | 5.09e-01 | -3.54e+00 | 4.02e-04 | 8.32e-03 | -3.80e-01 |
| CHOL | cg25033767 | chr6:43077138 | CGI:chr6:43076196-43077319 | promoter,gene body | 2.59e-01 | 5.40e-01 | -3.10e+00 | 1.96e-03 | 1.07e-02 | -2.81e-01 |
| CHOL | cg20819617 | chr6:43077314 | CGI:chr6:43076196-43077319 | promoter,gene body | 2.64e-01 | 5.12e-01 | -2.43e+00 | 1.50e-02 | 2.65e-02 | -2.48e-01 |
| CHOL | cg09674015 | chr6:43077449 | CGI:chr6:43076196-43077319 | promoter,gene body | 9.80e-02 | 2.35e-01 | -3.24e+00 | 1.18e-03 | 1.07e-02 | -1.37e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg15123159 | chr6:43077948 | CGI:chr6:43076196-43077319 | promoter,gene body | 6.20e-01 | 5.07e-01 | 8.80e+00 | 1.35e-18 | 6.50e-18 | 1.13e-01 |
Top |
Exon skipping events with PSI in TCGA for PTK7 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PTK7 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for PTK7 |
| TFs related to PTK7. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PTK7 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PTK7 |
| RBPs related to ES in PTK7. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | SAMD4A | exon_skip_451914 | 8.86e+00 | 9.85e-01 | 8.52e+00 | 1.07e-02 | Male-biased |
| UVM | G3BP2 | exon_skip_451936 | 9.03e+00 | 1.32e-02 | 9.31e+00 | 9.83e-01 | Female-biased |
| COAD | FMR1 | exon_skip_451939 | 8.67e+00 | 9.87e-01 | 8.31e+00 | 7.54e-03 | Male-biased |
| COAD | SAMD4A | exon_skip_451914 | 7.94e+00 | 3.43e-03 | 8.38e+00 | 9.90e-01 | Female-biased |
| LUAD | SAMD4A | exon_skip_451914 | 8.45e+00 | 9.83e-01 | 8.12e+00 | 9.97e-03 | Male-biased |
| BRCA | ZC3H10 | exon_skip_451926 | 6.28e+00 | 8.70e-04 | 7.74e+00 | 9.90e-01 | Female-biased |
| BRCA | ZC3H10 | exon_skip_451944 | 9.24e+00 | 2.49e-03 | 1.03e+01 | 9.96e-01 | Female-biased |
| ESCA | ZC3H10 | exon_skip_451944 | 9.77e+00 | 9.84e-01 | 9.37e+00 | 1.34e-02 | Male-biased |
| PCPG | ZC3H10 | exon_skip_451944 | 8.97e+00 | 2.00e-03 | 9.42e+00 | 9.95e-01 | Female-biased |
| MESO | ZC3H10 | exon_skip_451926 | 6.74e+00 | 9.82e-01 | 6.22e+00 | 2.14e-03 | Male-biased |
| MESO | ZC3H10 | exon_skip_451944 | 9.55e+00 | 9.86e-01 | 9.22e+00 | 1.17e-02 | Male-biased |
| GBM | SAMD4A | exon_skip_451914 | 8.05e+00 | 2.47e-03 | 8.52e+00 | 9.91e-01 | Female-biased |
| KIRC | ZC3H10 | exon_skip_451944 | 9.42e+00 | 9.83e-01 | 9.14e+00 | 1.43e-02 | Male-biased |
| HNSC | SAMD4A | exon_skip_451914 | 8.28e+00 | 4.38e-03 | 8.69e+00 | 9.90e-01 | Female-biased |
| SARC | SAMD4A | exon_skip_451914 | 8.77e+00 | 9.94e-01 | 8.08e+00 | 7.35e-04 | Male-biased |
| PTK7 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs191436113 | chr6:42817172:G:A | - | 0.305740513476381 | 0.0180336364865402 | LIHC | Female-baised eQTL |
| rs58260658 | chr6:42817298:A:G | - | 0.305740513476381 | 0.0180336364865402 | LIHC | Female-baised eQTL |
| rs117448892 | chr6:42827055:G:C | - | 0.305740513476381 | 0.0180336364865402 | LIHC | Female-baised eQTL |
| rs79727883 | chr6:42845564:G:A | - | 0.304982541908981 | 0.0189248569568585 | LIHC | Female-baised eQTL |
| rs77138402 | chr6:42846587:C:G | - | 0.304982541908981 | 0.0189248569568585 | LIHC | Female-baised eQTL |
| rs60307337 | chr6:42848610:G:A | - | 0.304982541908981 | 0.0189248569568585 | LIHC | Female-baised eQTL |
| rs73430540 | chr6:39879902:A:C | - | 0.201123816412271 | 0.025220803915054 | LIHC | Female-baised eQTL |
| rs9394915 | chr6:42683977:C:G | - | 0.154364545742045 | 0.00316421090796112 | STAD | Female-baised eQTL |
| rs6925759 | chr6:37586602:A:G | - | 0.118067538409547 | 0.0150061878124835 | STAD | Female-baised eQTL |
| rs9277928 | chr6:33160683:G:T | - | 0.0726019074622726 | 0.0160114188114713 | LGG | Female-baised eQTL |
| rs62397905 | chr6:47794015:A:G | - | 0.140274553023893 | 0.0232511895619651 | LGG | Female-baised eQTL |
| rs734181 | chr6:33162431:C:G | - | 0.0705939968702086 | 0.0240728754112026 | LGG | Female-baised eQTL |
| rs2235498 | chr6:33162653:G:A | - | 0.0705939968702086 | 0.0240728754112026 | LGG | Female-baised eQTL |
| rs62397900 | chr6:47775812:C:T | - | 0.139547664153802 | 0.0249920677792677 | LGG | Female-baised eQTL |
| rs62397901 | chr6:47778410:T:G | - | 0.139547664153802 | 0.0249920677792677 | LGG | Female-baised eQTL |
| rs62397903 | chr6:47781697:A:T | - | 0.139547664153802 | 0.0249920677792677 | LGG | Female-baised eQTL |
| rs75407071 | chr6:47783309:T:G | - | 0.139547664153802 | 0.0249920677792677 | LGG | Female-baised eQTL |
| rs62397904 | chr6:47786934:T:C | - | 0.139547664153802 | 0.0249920677792677 | LGG | Female-baised eQTL |
| rs1411048 | chr6:47775514:A:C | - | 0.130627240179009 | 0.0392011467840656 | LGG | Female-baised eQTL |
| rs59675532 | chr6:47774219:A:G | - | 0.130493415532869 | 0.0481927002742732 | LGG | Female-baised eQTL |
| rs1411046 | chr6:47775593:T:C | - | 0.130281069974826 | 0.0487905342309993 | LGG | Female-baised eQTL |
| rs1411045 | chr6:47775746:T:C | - | 0.130281069974826 | 0.0487905342309993 | LGG | Female-baised eQTL |
| rs7769464 | chr6:47776348:A:G | - | 0.130281069974826 | 0.0487905342309993 | LGG | Female-baised eQTL |
| rs7769915 | chr6:47776587:A:G | - | 0.130281069974826 | 0.0487905342309993 | LGG | Female-baised eQTL |
| rs7770508 | chr6:47776730:G:A | - | 0.130281069974826 | 0.0487905342309993 | LGG | Female-baised eQTL |
| rs78382807 | chr6:36353572:G:T | - | 0.163469968866124 | 0.0274854610658382 | BLCA | Female-baised eQTL |
| rs1938212 | chr6:48873145:G:C | - | -0.17219567931465 | 0.0484231817432508 | BLCA | Female-baised eQTL |
| rs602670 | chr6:52231476:C:T | - | -0.0570302643928767 | 0.0169658658308566 | LUAD | Female-baised eQTL |
| rs2064332 | chr6:52229258:C:T | - | -0.0558181786439995 | 0.0216197999592302 | LUAD | Female-baised eQTL |
| rs9471933 | chr6:42859867:C:G | - | -0.0520325815004424 | 0.0333517752014043 | LUAD | Female-baised eQTL |
| rs2782604 | chr6:52249775:C:T | - | -0.0504047755803143 | 0.0347269121122216 | LUAD | Female-baised eQTL |
| rs6458311 | chr6:42898554:A:G | - | -0.0511807333917013 | 0.035669089830937 | LUAD | Female-baised eQTL |
| rs10807284 | chr6:42900395:C:A | - | -0.0511807333917013 | 0.035669089830937 | LUAD | Female-baised eQTL |
| rs7773231 | chr6:42881457:A:T | - | -0.0507142250490179 | 0.0358091501757839 | LUAD | Female-baised eQTL |
| rs7758629 | chr6:42903526:C:A | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs7759112 | chr6:42903783:C:T | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs9462850 | chr6:42904737:C:T | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs7765132 | chr6:42905091:G:A | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs7740879 | chr6:42905641:A:G | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs7741547 | chr6:42906075:A:G | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs7741552 | chr6:42906085:A:G | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs34455103 | chr6:42907390:C:G | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs10223860 | chr6:42907645:T:G | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs9296401 | chr6:42907727:T:C | - | -0.0512059831033341 | 0.0359571372353969 | LUAD | Female-baised eQTL |
| rs1819325 | chr6:42892010:C:A | - | -0.0507817907543436 | 0.0361178072881682 | LUAD | Female-baised eQTL |
| rs2395940 | chr6:42892729:C:G | - | -0.0507817907543436 | 0.0361178072881682 | LUAD | Female-baised eQTL |
| rs4530854 | chr6:42895046:A:G | - | -0.0507817907543436 | 0.0361178072881682 | LUAD | Female-baised eQTL |
| rs2092554 | chr6:42896183:G:A | - | -0.0507817907543436 | 0.0361178072881682 | LUAD | Female-baised eQTL |
| rs7754294 | chr6:42903014:G:C | - | -0.0509004297768505 | 0.038311615668563 | LUAD | Female-baised eQTL |
| rs7740252 | chr6:42903307:T:C | - | -0.0509004297768505 | 0.038311615668563 | LUAD | Female-baised eQTL |
| rs7758576 | chr6:42903318:G:A | - | -0.0509004297768505 | 0.038311615668563 | LUAD | Female-baised eQTL |
| rs13206802 | chr6:42903410:G:A | - | -0.0509004297768505 | 0.038311615668563 | LUAD | Female-baised eQTL |
| rs591281 | chr6:42872521:G:A | - | -0.0499946244585162 | 0.0406089506626932 | LUAD | Female-baised eQTL |
| rs16891937 | chr6:39330674:T:C | - | 0.0609995141224499 | 0.043745720797901 | LUAD | Female-baised eQTL |
| rs4713957 | chr6:36308365:G:A | - | 0.0692463075530675 | 0.0145877457750451 | COAD | Female-baised eQTL |
| rs7769503 | chr6:36320874:G:T | - | 0.0521836430783526 | 0.04826410245893 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs467274 | chr6:33284050:T:C | - | -0.160809739621952 | 0.0103443011836524 | GBM | Male-baised eQTL |
| rs9381242 | chr6:43445343:G:T | - | 0.137627377255706 | 0.0462243631372536 | GBM | Male-baised eQTL |
| rs9885612 | chr6:40664363:G:A | - | 0.0614615653804088 | 0.00509649196618492 | LIHC | Male-baised eQTL |
| rs2465029 | chr6:51282043:A:C | - | 0.117157643832317 | 0.0120394136093272 | STAD | Male-baised eQTL |
| rs2397118 | chr6:52836345:C:T | - | -0.0483912554707128 | 9.43525078866997e-05 | KIRC | Male-baised eQTL |
| rs2397120 | chr6:52836759:G:A | - | -0.0483912554707128 | 9.43525078866997e-05 | KIRC | Male-baised eQTL |
| rs7755335 | chr6:52835216:G:A | - | -0.0483452291973926 | 9.65629063673347e-05 | KIRC | Male-baised eQTL |
| rs79878794 | chr6:48476578:A:G | - | 0.0429375056752442 | 0.000205551330998174 | KIRC | Male-baised eQTL |
| rs377106429 | chr6:48493050:T:C | - | 0.0424475269189078 | 0.000230722221532582 | KIRC | Male-baised eQTL |
| rs16877509 | chr6:48497685:T:G | - | 0.0424475269189078 | 0.000230722221532582 | KIRC | Male-baised eQTL |
| rs6915375 | chr6:48500482:C:A | - | 0.0424475269189078 | 0.000230722221532582 | KIRC | Male-baised eQTL |
| rs6922415 | chr6:48502134:A:G | - | 0.0424475269189078 | 0.000230722221532582 | KIRC | Male-baised eQTL |
| rs80236434 | chr6:48473968:C:T | - | 0.0424090106294213 | 0.000243176749544027 | KIRC | Male-baised eQTL |
| rs16877528 | chr6:48512376:G:C | - | 0.0426160572608951 | 0.000298775703504774 | KIRC | Male-baised eQTL |
| rs11967539 | chr6:48513016:C:A | - | 0.0426160572608951 | 0.000298775703504774 | KIRC | Male-baised eQTL |
| rs75738805 | chr6:39141741:C:T | - | 0.0521754629570074 | 0.000367815129254141 | KIRC | Male-baised eQTL |
| rs7450404 | chr6:48517013:G:A | - | 0.0410568906280673 | 0.000378096664223297 | KIRC | Male-baised eQTL |
| rs7747207 | chr6:48520468:T:A | - | 0.0410568906280673 | 0.000378096664223297 | KIRC | Male-baised eQTL |
| rs2894754 | chr6:48525026:A:G | - | 0.0410050470378196 | 0.000392144887383753 | KIRC | Male-baised eQTL |
| rs76964252 | chr6:48525138:A:G | - | 0.0410050470378196 | 0.000392144887383753 | KIRC | Male-baised eQTL |
| rs75745660 | chr6:48525655:A:G | - | 0.0410050470378196 | 0.000392144887383753 | KIRC | Male-baised eQTL |
| rs76674784 | chr6:48531981:G:T | - | 0.0410050470378196 | 0.000392144887383753 | KIRC | Male-baised eQTL |
| rs112633131 | chr6:48538881:G:A | - | 0.0409951013016781 | 0.000397249589479491 | KIRC | Male-baised eQTL |
| rs12191295 | chr6:36130556:T:C | - | -0.0502230381722832 | 0.000432419015762522 | KIRC | Male-baised eQTL |
| rs17813135 | chr6:51310577:T:C | - | 0.0416290143968424 | 0.000524359062725421 | KIRC | Male-baised eQTL |
| rs6920476 | chr6:48476712:G:A | - | 0.0395368546431954 | 0.00052617633277636 | KIRC | Male-baised eQTL |
| rs7760808 | chr6:48514212:C:T | - | 0.040559639722977 | 0.000588496542288783 | KIRC | Male-baised eQTL |
| rs1968872 | chr6:41217159:G:A | - | 0.0397522784706889 | 0.000722938344049649 | KIRC | Male-baised eQTL |
| rs16877490 | chr6:48469021:C:T | - | 0.0388992796452145 | 0.000883583120631297 | KIRC | Male-baised eQTL |
| rs2252430 | chr6:36136144:G:A | - | -0.0475438016215175 | 0.00090858457635574 | KIRC | Male-baised eQTL |
| rs76003563 | chr6:48467858:C:T | - | 0.0385103401822578 | 0.000957524660371611 | KIRC | Male-baised eQTL |
| rs75441204 | chr6:48487620:C:A | - | 0.037205565601285 | 0.00106312963148098 | KIRC | Male-baised eQTL |
| rs16877498 | chr6:48473837:A:G | - | 0.0370958476599324 | 0.00111193368608023 | KIRC | Male-baised eQTL |
| rs874407 | chr6:36319826:A:T | - | 0.0413746293187249 | 0.00118888142311889 | KIRC | Male-baised eQTL |
| rs874064 | chr6:36320394:T:C | - | 0.0400968438302513 | 0.0019416305446427 | KIRC | Male-baised eQTL |
| rs56167824 | chr6:41218983:A:G | - | 0.0370196197637966 | 0.00221449784715301 | KIRC | Male-baised eQTL |
| rs2803492 | chr6:41223483:C:T | - | 0.0370196197637966 | 0.00221449784715301 | KIRC | Male-baised eQTL |
| rs115713676 | chr6:39133760:C:T | - | 0.0452307440514401 | 0.00232215058414777 | KIRC | Male-baised eQTL |
| rs58253054 | chr6:39135694:T:C | - | 0.0452307440514401 | 0.00232215058414777 | KIRC | Male-baised eQTL |
| rs10947782 | chr6:39139131:G:A | - | 0.0452307440514401 | 0.00232215058414777 | KIRC | Male-baised eQTL |
| rs11755423 | chr6:39139336:G:T | - | 0.0452307440514401 | 0.00232215058414777 | KIRC | Male-baised eQTL |
| rs7769503 | chr6:36320874:G:T | - | 0.0376116367883886 | 0.00383334124271527 | KIRC | Male-baised eQTL |
| rs9471012 | chr6:39225842:G:A | - | 0.0326666670802385 | 0.00839315336441493 | KIRC | Male-baised eQTL |
| rs1749167 | chr6:51069856:G:A | - | 0.0339259131660973 | 0.00852279531309849 | KIRC | Male-baised eQTL |
| rs141976744 | chr6:48848246:T:A | - | 0.0335463829133134 | 0.00930729228253159 | KIRC | Male-baised eQTL |
| rs12197415 | chr6:51018546:T:A | - | 0.0357588602068736 | 0.0098994371227632 | KIRC | Male-baised eQTL |
| rs76480727 | chr6:47195286:T:C | - | 0.0339279312350377 | 0.0110217960085791 | KIRC | Male-baised eQTL |
| rs6927828 | chr6:48867175:G:A | - | 0.0329080594358063 | 0.0113607632631389 | KIRC | Male-baised eQTL |
| rs10484882 | chr6:52146671:G:A | - | 0.0312299095721317 | 0.0131190200489776 | KIRC | Male-baised eQTL |
| rs77437291 | chr6:51022928:G:A | - | 0.0343519844561399 | 0.0145833135469261 | KIRC | Male-baised eQTL |
| rs12215645 | chr6:51073856:T:A | - | 0.0333518419254581 | 0.0155364686178916 | KIRC | Male-baised eQTL |
| rs112586589 | chr6:51056989:G:A | - | 0.0333305084018481 | 0.0155540377636731 | KIRC | Male-baised eQTL |
| rs115616960 | chr6:51058567:C:T | - | 0.0333305084018481 | 0.0155540377636731 | KIRC | Male-baised eQTL |
| rs76504177 | chr6:51060365:T:G | - | 0.0332678701648295 | 0.016039144330316 | KIRC | Male-baised eQTL |
| rs12211338 | chr6:51086009:G:A | - | 0.0327382100294465 | 0.0168989589715475 | KIRC | Male-baised eQTL |
| rs12195500 | chr6:51091559:C:T | - | 0.0327382100294465 | 0.0168989589715475 | KIRC | Male-baised eQTL |
| rs12211323 | chr6:51076993:T:C | - | 0.0327115263394459 | 0.017011520415677 | KIRC | Male-baised eQTL |
| rs12213173 | chr6:51077802:T:A | - | 0.0327115263394459 | 0.017011520415677 | KIRC | Male-baised eQTL |
| rs113804737 | chr6:51078496:C:A | - | 0.0327115263394459 | 0.017011520415677 | KIRC | Male-baised eQTL |
| rs79113400 | chr6:51080629:A:T | - | 0.0327115263394459 | 0.017011520415677 | KIRC | Male-baised eQTL |
| rs12211727 | chr6:51080955:C:A | - | 0.0327115263394459 | 0.017011520415677 | KIRC | Male-baised eQTL |
| rs77373174 | chr6:51082239:T:C | - | 0.0327115263394459 | 0.017011520415677 | KIRC | Male-baised eQTL |
| rs116024144 | chr6:51032710:T:C | - | 0.0327230235073116 | 0.0182463272946637 | KIRC | Male-baised eQTL |
| rs142624004 | chr6:51036272:A:T | - | 0.0327230235073116 | 0.0182463272946637 | KIRC | Male-baised eQTL |
| rs9381930 | chr6:51039911:T:A | - | 0.0327230235073116 | 0.0182463272946637 | KIRC | Male-baised eQTL |
| rs12211462 | chr6:51050356:C:A | - | 0.0327230235073116 | 0.0182463272946637 | KIRC | Male-baised eQTL |
| rs4530857 | chr6:51053562:G:A | - | 0.0327230235073116 | 0.0182463272946637 | KIRC | Male-baised eQTL |
| rs12204921 | chr6:51042014:G:C | - | 0.0322318917993382 | 0.0205862070538203 | KIRC | Male-baised eQTL |
| rs11759163 | chr6:36938065:C:T | - | 0.0303698404168319 | 0.0206857360846918 | KIRC | Male-baised eQTL |
| rs75974865 | chr6:47097244:G:A | - | 0.0275197923071769 | 0.0370539661367493 | KIRC | Male-baised eQTL |
| rs1532138 | chr6:47101347:G:A | - | 0.0276615125704103 | 0.0388678251715513 | KIRC | Male-baised eQTL |
| rs62401831 | chr6:47102432:G:T | - | 0.0275889943949589 | 0.0400342473767929 | KIRC | Male-baised eQTL |
| rs17246556 | chr6:52268696:A:G | - | 0.0302817852234913 | 0.0449510900816461 | KIRC | Male-baised eQTL |
| rs72856286 | chr6:41135788:G:C | - | 0.0443253267701193 | 0.00394025606278954 | BLCA | Male-baised eQTL |
| rs62396337 | chr6:41136212:C:T | - | 0.0443253267701193 | 0.00394025606278954 | BLCA | Male-baised eQTL |
| rs62396338 | chr6:41137292:T:A | - | 0.0443253267701193 | 0.00394025606278954 | BLCA | Male-baised eQTL |
| rs62396341 | chr6:41138805:T:G | - | 0.0443253267701193 | 0.00394025606278954 | BLCA | Male-baised eQTL |
| rs62396342 | chr6:41139117:A:G | - | 0.0443253267701193 | 0.00394025606278954 | BLCA | Male-baised eQTL |
| rs72856293 | chr6:41140090:G:C | - | 0.0443253267701193 | 0.00394025606278954 | BLCA | Male-baised eQTL |
| rs6905117 | chr6:41122510:T:C | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs62396312 | chr6:41123848:G:C | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs62396315 | chr6:41126168:G:A | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs11970568 | chr6:41126596:T:G | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs11964090 | chr6:41131426:T:C | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs6911977 | chr6:41133122:C:G | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs6923053 | chr6:41134344:G:A | - | 0.0424068148690873 | 0.0059039432633904 | BLCA | Male-baised eQTL |
| rs76209811 | chr6:41100861:A:G | - | 0.0397869670753029 | 0.00894567165526398 | BLCA | Male-baised eQTL |
| rs62396301 | chr6:41100862:A:C | - | 0.0397869670753029 | 0.00894567165526398 | BLCA | Male-baised eQTL |
| rs6924867 | chr6:41122431:A:G | - | 0.0406275524235271 | 0.00972264009322113 | BLCA | Male-baised eQTL |
| rs72856259 | chr6:41100761:G:A | - | 0.0388348126525297 | 0.0111799218676993 | BLCA | Male-baised eQTL |
| rs62396300 | chr6:41100841:G:C | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs11961582 | chr6:41101454:C:G | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs67151216 | chr6:41101455:C:G | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs61730401 | chr6:41108459:A:G | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs72856266 | chr6:41108528:G:C | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs62396305 | chr6:41109485:T:C | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs62396306 | chr6:41110152:A:T | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs78609059 | chr6:41118916:T:A | - | 0.0388286729458849 | 0.011817587978641 | BLCA | Male-baised eQTL |
| rs115980554 | chr6:34488855:C:T | - | 0.049988729913617 | 0.0145104631032991 | BLCA | Male-baised eQTL |
| rs75489661 | chr6:34490548:C:G | - | 0.049988729913617 | 0.0145104631032991 | BLCA | Male-baised eQTL |
| rs9470961 | chr6:39007495:A:T | - | 0.0508646607809163 | 0.0179332747508088 | BLCA | Male-baised eQTL |
| rs72856290 | chr6:41137983:A:C | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs62396340 | chr6:41138475:A:C | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs62396343 | chr6:41142126:A:G | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs62396344 | chr6:41143543:A:G | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs62396347 | chr6:41145639:G:A | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs62396348 | chr6:41145790:T:G | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs72856298 | chr6:41146182:T:C | - | 0.0421618321934199 | 0.0199943979125874 | BLCA | Male-baised eQTL |
| rs2478887 | chr6:51371520:G:A | - | 0.0384901538793577 | 0.0274906063143468 | BLCA | Male-baised eQTL |
| rs12332906 | chr6:42790571:G:T | - | 0.053866598339236 | 0.027553846631198 | BLCA | Male-baised eQTL |
| rs11969526 | chr6:41123568:C:A | - | 0.0400186599461225 | 0.0279445890222732 | BLCA | Male-baised eQTL |
| rs62396314 | chr6:41125900:A:T | - | 0.0400186599461225 | 0.0279445890222732 | BLCA | Male-baised eQTL |
| rs140593720 | chr6:41129743:A:T | - | 0.0400186599461225 | 0.0279445890222732 | BLCA | Male-baised eQTL |
| rs62396334 | chr6:41131788:G:C | - | 0.0400186599461225 | 0.0279445890222732 | BLCA | Male-baised eQTL |
| rs6918289 | chr6:41134089:G:T | - | 0.0400186599461225 | 0.0279445890222732 | BLCA | Male-baised eQTL |
| rs489448 | chr6:44674288:G:T | - | 0.0331220364079768 | 0.0410678739258329 | BLCA | Male-baised eQTL |
| rs9277467 | chr6:33085667:G:A | - | 0.0778566123809906 | 0.0198804724625738 | LUAD | Male-baised eQTL |
| rs2815808 | chr6:36145258:G:C | - | -0.063406487898019 | 0.0357589502966116 | LUAD | Male-baised eQTL |
| rs9462544 | chr6:39423617:G:T | - | 0.074156722266651 | 0.0361346864320716 | LUAD | Male-baised eQTL |
| rs113820722 | chr6:41752344:A:T | - | 0.0671724712510789 | 0.0385865327009279 | LUAD | Male-baised eQTL |
| rs77534627 | chr6:48212144:C:A | - | 0.056753908525936 | 0.00803999621410787 | COAD | Male-baised eQTL |
| rs526428 | chr6:48311728:C:T | - | -0.0572583777326941 | 0.00999568823745044 | COAD | Male-baised eQTL |
| rs73730813 | chr6:37759872:A:G | - | 0.0632343931968919 | 0.0109232102324438 | COAD | Male-baised eQTL |
| rs9473260 | chr6:48226458:G:A | - | 0.0532598090815024 | 0.0133350640921821 | COAD | Male-baised eQTL |
| rs9463378 | chr6:48183398:G:A | - | 0.0526713605245894 | 0.0156876021535486 | COAD | Male-baised eQTL |
| rs9473276 | chr6:48296173:T:A | - | 0.0606210528156182 | 0.0166792631527581 | COAD | Male-baised eQTL |
| rs143675506 | chr6:37759141:C:T | - | 0.0820424129660571 | 0.0191573805283929 | COAD | Male-baised eQTL |
| rs10947659 | chr6:37141909:C:A | - | 0.0548149062755826 | 0.0199175621769755 | COAD | Male-baised eQTL |
| rs9463173 | chr6:46049600:T:C | - | 0.0720593718570158 | 0.0201235577219277 | COAD | Male-baised eQTL |
| rs112308382 | chr6:48153082:G:A | - | 0.0523110443985215 | 0.0261806936998425 | COAD | Male-baised eQTL |
| rs9473262 | chr6:48233156:A:C | - | 0.0495282052756162 | 0.0265278354623164 | COAD | Male-baised eQTL |
| rs4711906 | chr6:48264595:G:A | - | 0.0498192577095434 | 0.0292987258981372 | COAD | Male-baised eQTL |
| rs12213525 | chr6:48207321:C:T | - | 0.0484964226568121 | 0.0327360149459059 | COAD | Male-baised eQTL |
| rs77011928 | chr6:37761332:G:T | - | 0.0740420913430049 | 0.0381049675228542 | COAD | Male-baised eQTL |
| rs77953170 | chr6:37761430:C:G | - | 0.0740420913430049 | 0.0381049675228542 | COAD | Male-baised eQTL |
| rs7762853 | chr6:48167305:T:C | - | 0.047391295441105 | 0.0381224274522098 | COAD | Male-baised eQTL |
| rs6904352 | chr6:37760843:G:C | - | 0.0739191810673899 | 0.0385873073329172 | COAD | Male-baised eQTL |
| rs74577143 | chr6:37760983:T:C | - | 0.0739191810673899 | 0.0385873073329172 | COAD | Male-baised eQTL |
| rs2769934 | chr6:41872855:A:G | - | -0.0404151230242821 | 0.0408934044793946 | COAD | Male-baised eQTL |
| rs79704198 | chr6:46047331:G:A | - | 0.0742377068234985 | 0.042137139952402 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000112655 |
| CpG Site: cg18336453 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.38957235630636 | |
 | Gene ID: ENSG00000112655 |
| CpG Site: cg06108459 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.38957235630636 | |
 | Gene ID: ENSG00000112655 |
| CpG Site: cg26352161 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.39350379780477 | |
 | Gene ID: ENSG00000112655 |
| CpG Site: cg06152926 | |
| Position to Gene: gene | |
| Male Effect: -0.250216823830817 | |
| Female Effect: - | |
 | Gene ID: ENSG00000112655 |
| CpG Site: cg15123159 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.394635816871971 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg06152926 | chr6:43090089 | gene | -0.250216823830817 | 4.07696330272037e-17 | -0.575257326775869 | 8.820319169719182e-21 | STAD |
| cg15123159 | chr6:43077948 | gene,promoter | -0.394635816871971 | 2.07935148406825e-07 | -0.40749695909745726 | 3.286463129301107e-10 | STAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg18336453 | chr6:43114558 | gene | -0.38957235630636 | 2.26637876660705e-08 | -0.3380212933618418 | 2.7506484275543885e-11 | THCA |
| cg06108459 | chr6:43121311 | gene | -0.38957235630636 | 2.26637876660705e-08 | -0.3380212933618418 | 2.7506484275543885e-11 | THCA |
| cg26352161 | chr6:43104004 | gene | -0.39350379780477 | 2.07284828011802e-05 | -0.3319645767048479 | 7.181026981068335e-08 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of PTK7 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000112655 | PTK7 | C1535926 | Neurodevelopmental Disorders | 1 | CTD_human |
