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Gene: ENSG00000111913 |
Summary for FAM65B |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000111913 | Gene symbol | FAM65B |
| Gene name | RHO family interacting cell polarization regulator 2 | |
| HGNC | 13872 | |
| Entrez ID | 9750 | |
| Gene type | protein_coding | |
| Synonyms | RIPOR2|KIAA0386|DIFF48|MYONAP | |
| UniProtAcc | Q9Y4F9 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for FAM65B |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FAM65B | 6.09e+02 | -1.41e+00 | 4.03e-01 | -3.49e+00 | 4.92e-04 | 6.71e-03 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FAM65B | 9.85e+02 | 1.08e+00 | 3.42e-01 | 3.15e+00 | 1.66e-03 | 4.29e-03 | THCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FAM65B | 1.22e+03 | 1.09e+00 | 2.01e-01 | 5.40e+00 | 6.63e-08 | 2.90e-07 | KIRC |
Top |
Sex-biased somatic mutation for FAM65B |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for FAM65B |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg12883629 | chr6:25042269 | CGI:chr6:25139692-25140018 | promoter | 6.25e-01 | 5.20e-01 | 3.35e+00 | 8.14e-04 | 3.24e-03 | 1.06e-01 |
| KIRP | cg14083015 | chr6:25041862 | CGI:chr6:25139692-25140018 | promoter,exon,CDS,gene body | 4.87e-01 | 3.82e-01 | 2.71e+00 | 6.80e-03 | 1.67e-02 | 1.06e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg26336265 | chr6:25042727 | CGI:chr6:25139692-25140018 | promoter | 5.99e-01 | 7.36e-01 | -2.84e+00 | 4.44e-03 | 7.47e-03 | -1.37e-01 |
| LUSC | cg19882886 | chr6:25042818 | CGI:chr6:25139692-25140018 | promoter | 7.98e-01 | 9.05e-01 | -2.65e+00 | 8.12e-03 | 1.18e-02 | -1.08e-01 |
| BLCA | cg26336265 | chr6:25042727 | CGI:chr6:25139692-25140018 | promoter | 5.93e-01 | 7.87e-01 | -3.47e+00 | 5.20e-04 | 1.37e-03 | -1.94e-01 |
| BLCA | cg19882886 | chr6:25042818 | CGI:chr6:25139692-25140018 | promoter | 7.71e-01 | 9.16e-01 | -3.76e+00 | 1.72e-04 | 5.92e-04 | -1.45e-01 |
| LIHC | cg26336265 | chr6:25042727 | CGI:chr6:25139692-25140018 | promoter | 6.30e-01 | 7.40e-01 | -2.56e+00 | 1.04e-02 | 1.27e-02 | -1.09e-01 |
| KIRP | cg14083015 | chr6:25041862 | CGI:chr6:25139692-25140018 | promoter,exon,CDS,gene body | 3.82e-01 | 6.70e-01 | -3.51e+00 | 4.49e-04 | 9.24e-04 | -2.88e-01 |
| KIRP | cg08578703 | chr6:25042267 | CGI:chr6:25139692-25140018 | promoter | 2.06e-01 | 3.62e-01 | -4.40e+00 | 1.10e-05 | 4.04e-05 | -1.56e-01 |
| KIRP | cg00164997 | chr6:25042320 | CGI:chr6:25139692-25140018 | promoter | 2.40e-01 | 3.76e-01 | -4.17e+00 | 3.06e-05 | 9.54e-05 | -1.35e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg26336265 | chr6:25042727 | CGI:chr6:25139692-25140018 | promoter | 7.23e-01 | 8.51e-01 | -8.85e+00 | 8.64e-19 | 4.23e-18 | -1.28e-01 |
| HNSC | cg14083015 | chr6:25041862 | CGI:chr6:25139692-25140018 | promoter,exon,CDS,gene body | 7.48e-01 | 8.75e-01 | -2.54e+00 | 1.09e-02 | 1.95e-02 | -1.27e-01 |
| COAD | cg19882886 | chr6:25042818 | CGI:chr6:25139692-25140018 | promoter | 6.47e-01 | 7.88e-01 | -2.37e+00 | 1.78e-02 | 2.39e-02 | -1.41e-01 |
Top |
Exon skipping events with PSI in TCGA for FAM65B |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for FAM65B |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LAML | FAM65B-201 | chr6_25030875_- | 1.51e-01 | 1.99e-01 | -2.17e+00 | 3.00e-02 | 4.94e-02 | -4.80e-02 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for FAM65B |
| TFs related to FAM65B. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | AIRE | FAM65B | 3.92e+00 | 9.81e-01 | 2.81e+00 | 5.64e-03 | Male-biased |
| CHOL | CDC5L | FAM65B | 4.52e+00 | 9.90e-01 | 3.40e+00 | 5.44e-03 | Male-biased |
| CHOL | FOXP3 | FAM65B | 4.10e+00 | 9.86e-01 | 2.93e+00 | 4.32e-03 | Male-biased |
| CHOL | HNF1A | FAM65B | 3.87e+00 | 9.84e-01 | 2.47e+00 | 1.63e-03 | Male-biased |
| CHOL | IRX2 | FAM65B | 4.41e+00 | 9.82e-01 | 3.48e+00 | 1.19e-02 | Male-biased |
| CHOL | MEOX2 | FAM65B | 3.98e+00 | 9.87e-01 | 2.58e+00 | 1.64e-03 | Male-biased |
| CHOL | MYNN | FAM65B | 3.84e+00 | 9.82e-01 | 2.54e+00 | 2.53e-03 | Male-biased |
| CHOL | NANOG | FAM65B | 3.87e+00 | 9.85e-01 | 2.30e+00 | 7.57e-04 | Male-biased |
| CHOL | NFATC1 | FAM65B | 4.03e+00 | 9.81e-01 | 3.00e+00 | 7.60e-03 | Male-biased |
| CHOL | NFATC2 | FAM65B | 4.09e+00 | 9.85e-01 | 2.97e+00 | 5.41e-03 | Male-biased |
| CHOL | NFATC4 | FAM65B | 4.24e+00 | 9.81e-01 | 3.29e+00 | 1.08e-02 | Male-biased |
| CHOL | NKX2-2 | FAM65B | 3.96e+00 | 9.83e-01 | 2.82e+00 | 4.84e-03 | Male-biased |
| CHOL | POU1F1 | FAM65B | 4.12e+00 | 9.84e-01 | 3.06e+00 | 6.84e-03 | Male-biased |
| CHOL | POU5F1B | FAM65B | 4.05e+00 | 9.88e-01 | 2.65e+00 | 1.65e-03 | Male-biased |
| CHOL | SOX10 | FAM65B | 3.88e+00 | 9.84e-01 | 2.57e+00 | 2.32e-03 | Male-biased |
| CHOL | SOX17 | FAM65B | 3.87e+00 | 9.84e-01 | 2.53e+00 | 2.09e-03 | Male-biased |
| CHOL | SOX9 | FAM65B | 3.77e+00 | 9.81e-01 | 2.37e+00 | 1.58e-03 | Male-biased |
| CHOL | ZNF584 | FAM65B | 3.75e+00 | 9.80e-01 | 2.40e+00 | 1.95e-03 | Male-biased |
| LAML | AIRE | FAM65B | 2.94e+00 | 2.43e-03 | 4.19e+00 | 9.84e-01 | Female-biased |
| LAML | BATF | FAM65B | 3.02e+00 | 2.22e-03 | 4.29e+00 | 9.86e-01 | Female-biased |
| LAML | CDC5L | FAM65B | 3.45e+00 | 1.90e-03 | 4.78e+00 | 9.93e-01 | Female-biased |
| LAML | FOXI1 | FAM65B | 2.94e+00 | 1.48e-03 | 4.32e+00 | 9.87e-01 | Female-biased |
| LAML | FOXP3 | FAM65B | 2.79e+00 | 7.07e-04 | 4.34e+00 | 9.89e-01 | Female-biased |
| LAML | HNF1A | FAM65B | 2.65e+00 | 6.94e-04 | 4.21e+00 | 9.86e-01 | Female-biased |
| LAML | IRX2 | FAM65B | 3.67e+00 | 9.81e-03 | 4.57e+00 | 9.82e-01 | Female-biased |
| LAML | MEOX2 | FAM65B | 2.68e+00 | 1.15e-03 | 4.12e+00 | 9.84e-01 | Female-biased |
| LAML | NFATC1 | FAM65B | 3.27e+00 | 6.71e-03 | 4.27e+00 | 9.81e-01 | Female-biased |
| LAML | NFATC2 | FAM65B | 3.26e+00 | 6.21e-03 | 4.28e+00 | 9.82e-01 | Female-biased |
| LAML | NFATC4 | FAM65B | 3.58e+00 | 8.50e-03 | 4.52e+00 | 9.83e-01 | Female-biased |
| LAML | NKX2-2 | FAM65B | 2.77e+00 | 7.39e-04 | 4.31e+00 | 9.88e-01 | Female-biased |
| LAML | POU1F1 | FAM65B | 3.14e+00 | 2.19e-03 | 4.43e+00 | 9.88e-01 | Female-biased |
| LAML | POU5F1B | FAM65B | 2.68e+00 | 6.91e-04 | 4.24e+00 | 9.87e-01 | Female-biased |
| LAML | SOX10 | FAM65B | 2.73e+00 | 1.09e-03 | 4.18e+00 | 9.85e-01 | Female-biased |
| LAML | SOX8 | FAM65B | 2.55e+00 | 7.54e-04 | 4.08e+00 | 9.83e-01 | Female-biased |
| LAML | SOX9 | FAM65B | 2.55e+00 | 5.34e-04 | 4.17e+00 | 9.86e-01 | Female-biased |
| LAML | ZNF317 | FAM65B | 2.80e+00 | 2.10e-03 | 4.08e+00 | 9.82e-01 | Female-biased |
| LAML | ZNF595 | FAM65B | 3.39e+00 | 6.96e-03 | 4.38e+00 | 9.83e-01 | Female-biased |
| FAM65B related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for FAM65B |
| RBPs related to ES in FAM65B. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| FAM65B related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs76355312 | chr6:15252465:C:T | - | 0.407311236918398 | 1.04617459208793e-05 | GBM | Female-baised eQTL |
| rs74500897 | chr6:27058958:A:T | - | 0.182812124914575 | 0.0212356873117665 | LUSC | Female-baised eQTL |
| rs76371153 | chr6:27066499:G:A | - | 0.182812124914575 | 0.0212356873117665 | LUSC | Female-baised eQTL |
| rs78063424 | chr6:27069795:C:G | - | 0.182812124914575 | 0.0212356873117665 | LUSC | Female-baised eQTL |
| rs5003335 | chr6:27070420:A:G | - | 0.182812124914575 | 0.0212356873117665 | LUSC | Female-baised eQTL |
| rs79619645 | chr6:27072975:G:T | - | 0.182812124914575 | 0.0212356873117665 | LUSC | Female-baised eQTL |
| rs75696082 | chr6:22975565:A:G | - | 0.126406232404983 | 0.022821933263158 | LUSC | Female-baised eQTL |
| rs7741953 | chr6:18445661:A:G | - | 0.117047418331917 | 0.026235868980338 | LUSC | Female-baised eQTL |
| rs77825407 | chr6:27042689:T:G | - | 0.175151638413027 | 0.0386662932926618 | LUSC | Female-baised eQTL |
| rs111634318 | chr6:27047938:A:G | - | 0.175151638413027 | 0.0386662932926618 | LUSC | Female-baised eQTL |
| rs492591 | chr6:20018145:A:G | - | 0.16687676592875 | 2.80410662131545e-05 | STAD | Female-baised eQTL |
| rs6901175 | chr6:32230750:G:A | - | 0.0732116257486078 | 0.0473950293327687 | STAD | Female-baised eQTL |
| rs62401665 | chr6:31027755:T:C | - | 0.124293381946872 | 0.0114923501544433 | KIRC | Female-baised eQTL |
| rs62401667 | chr6:31030243:C:T | - | 0.123017709218939 | 0.0136596917221619 | KIRC | Female-baised eQTL |
| rs62401668 | chr6:31030274:T:C | - | 0.123017709218939 | 0.0136596917221619 | KIRC | Female-baised eQTL |
| rs62401669 | chr6:31030291:G:T | - | 0.123017709218939 | 0.0136596917221619 | KIRC | Female-baised eQTL |
| rs111996227 | chr6:31030410:G:A | - | 0.119020385437987 | 0.020466614000026 | KIRC | Female-baised eQTL |
| rs62401670 | chr6:31030676:G:A | - | 0.119020385437987 | 0.020466614000026 | KIRC | Female-baised eQTL |
| rs62401671 | chr6:31030924:C:A | - | 0.119020385437987 | 0.020466614000026 | KIRC | Female-baised eQTL |
| rs62401672 | chr6:31031004:C:T | - | 0.119020385437987 | 0.020466614000026 | KIRC | Female-baised eQTL |
| rs111673650 | chr6:31031140:C:T | - | 0.119020385437987 | 0.020466614000026 | KIRC | Female-baised eQTL |
| rs79027726 | chr6:31031238:A:G | - | 0.119673496722893 | 0.0210411166215648 | KIRC | Female-baised eQTL |
| rs111414258 | chr6:31031329:C:T | - | 0.119673496722893 | 0.0210411166215648 | KIRC | Female-baised eQTL |
| rs62401673 | chr6:31031770:T:C | - | 0.119673496722893 | 0.0210411166215648 | KIRC | Female-baised eQTL |
| rs281860333 | chr6:31271830:G:A | - | 0.115245111794087 | 0.0337772041488044 | KIRC | Female-baised eQTL |
| rs13215261 | chr6:24114366:G:A | - | 0.176825153899501 | 0.035546143875339 | KIRC | Female-baised eQTL |
| rs2244546 | chr6:31468056:C:G | - | 0.126931518264065 | 0.0381532732096213 | KIRC | Female-baised eQTL |
| rs74340554 | chr6:31031325:T:C | - | 0.107358256950575 | 0.0467905725492019 | KIRC | Female-baised eQTL |
| rs67058142 | chr6:31274016:G:A | - | 0.112361924718667 | 0.0470930925802375 | KIRC | Female-baised eQTL |
| rs75266400 | chr6:23553506:A:C | - | 0.0859242128541689 | 1.37472019724851e-05 | LUAD | Female-baised eQTL |
| rs74725448 | chr6:23551842:G:A | - | 0.0759756393571038 | 7.66543201793464e-05 | LUAD | Female-baised eQTL |
| rs112683537 | chr6:31337158:C:T | - | 0.0667982810431678 | 0.00118917854450779 | LUAD | Female-baised eQTL |
| rs62395272 | chr6:31426647:C:T | - | 0.0511260631987389 | 0.00130162342456539 | LUAD | Female-baised eQTL |
| rs77607283 | chr6:31337823:A:G | - | 0.062441101184143 | 0.00291359469471309 | LUAD | Female-baised eQTL |
| rs76269511 | chr6:31323036:C:T | - | 0.0598431842000765 | 0.0039550220365699 | LUAD | Female-baised eQTL |
| rs73731021 | chr6:31320830:C:G | - | 0.0597770832040152 | 0.00407505824300486 | LUAD | Female-baised eQTL |
| rs115446347 | chr6:31333955:T:C | - | 0.0648477103964111 | 0.00420043737461325 | LUAD | Female-baised eQTL |
| rs147109807 | chr6:31316576:A:G | - | 0.064828362071092 | 0.00425239150721633 | LUAD | Female-baised eQTL |
| rs188003338 | chr6:31317636:T:C | - | 0.064828362071092 | 0.00425239150721633 | LUAD | Female-baised eQTL |
| rs113997854 | chr6:31305050:C:T | - | 0.0648279718943335 | 0.00425284541923357 | LUAD | Female-baised eQTL |
| rs375232998 | chr6:31336632:C:T | - | 0.0594362531127768 | 0.00444502764149812 | LUAD | Female-baised eQTL |
| rs58490916 | chr6:31302609:T:C | - | 0.050844174608494 | 0.00452235948315091 | LUAD | Female-baised eQTL |
| rs62400916 | chr6:23558046:C:T | - | 0.0492759455010238 | 0.00551052905907091 | LUAD | Female-baised eQTL |
| rs73728845 | chr6:31339404:G:C | - | 0.0586519089250627 | 0.00551831521407702 | LUAD | Female-baised eQTL |
| rs73730049 | chr6:31305966:C:T | - | 0.0562581302342584 | 0.00739065756795982 | LUAD | Female-baised eQTL |
| rs9378230 | chr6:31312802:G:A | - | 0.0562263430684867 | 0.00742309821773941 | LUAD | Female-baised eQTL |
| rs73728849 | chr6:31343729:G:A | - | 0.056265587285842 | 0.00746081848681508 | LUAD | Female-baised eQTL |
| rs7771432 | chr6:31312973:C:T | - | 0.0562092103691248 | 0.00751311706863682 | LUAD | Female-baised eQTL |
| rs6941926 | chr6:31313452:C:G | - | 0.0562092103691248 | 0.00751311706863682 | LUAD | Female-baised eQTL |
| rs56761367 | chr6:31314852:C:T | - | 0.0562092103691248 | 0.00751311706863682 | LUAD | Female-baised eQTL |
| rs56006638 | chr6:31315157:A:G | - | 0.0562092103691248 | 0.00751311706863682 | LUAD | Female-baised eQTL |
| rs58742490 | chr6:31297599:G:A | - | 0.0555509930525808 | 0.00752781760296451 | LUAD | Female-baised eQTL |
| rs17198804 | chr6:31297731:C:T | - | 0.0555509930525808 | 0.00752781760296451 | LUAD | Female-baised eQTL |
| rs17192456 | chr6:31297787:A:G | - | 0.0555509930525808 | 0.00752781760296451 | LUAD | Female-baised eQTL |
| rs17198867 | chr6:31298194:G:T | - | 0.0555509930525808 | 0.00752781760296451 | LUAD | Female-baised eQTL |
| rs17198881 | chr6:31298221:C:T | - | 0.0555509930525808 | 0.00752781760296451 | LUAD | Female-baised eQTL |
| rs9265724 | chr6:31334356:T:A | - | 0.0561708654453289 | 0.00753210929051629 | LUAD | Female-baised eQTL |
| rs28752897 | chr6:31335696:C:A | - | 0.0561708654453289 | 0.00753210929051629 | LUAD | Female-baised eQTL |
| rs28752924 | chr6:31336145:T:G | - | 0.0561708654453289 | 0.00753210929051629 | LUAD | Female-baised eQTL |
| rs2894210 | chr6:31344247:G:A | - | 0.0560632159578096 | 0.00777829952078309 | LUAD | Female-baised eQTL |
| rs114128482 | chr6:31344254:G:A | - | 0.0560632159578096 | 0.00777829952078309 | LUAD | Female-baised eQTL |
| rs73728850 | chr6:31344314:T:C | - | 0.0560632159578096 | 0.00777829952078309 | LUAD | Female-baised eQTL |
| rs73728851 | chr6:31344424:G:A | - | 0.0560632159578096 | 0.00777829952078309 | LUAD | Female-baised eQTL |
| rs6905036 | chr6:31305369:T:C | - | 0.0550653773975302 | 0.00861854968943098 | LUAD | Female-baised eQTL |
| rs80053068 | chr6:31302249:T:C | - | 0.0546235121941945 | 0.00966807207740017 | LUAD | Female-baised eQTL |
| rs2394967 | chr6:31301352:G:A | - | 0.0535035990655846 | 0.0111363020458012 | LUAD | Female-baised eQTL |
| rs4523128 | chr6:31301605:T:C | - | 0.0524332760418967 | 0.0127060990547669 | LUAD | Female-baised eQTL |
| rs6930299 | chr6:31302691:T:G | - | 0.0524332760418967 | 0.0127060990547669 | LUAD | Female-baised eQTL |
| rs6908556 | chr6:31303174:C:A | - | 0.0524332760418967 | 0.0127060990547669 | LUAD | Female-baised eQTL |
| rs6913294 | chr6:31303347:G:A | - | 0.0524332760418967 | 0.0127060990547669 | LUAD | Female-baised eQTL |
| rs73730046 | chr6:31303443:G:A | - | 0.0524332760418967 | 0.0127060990547669 | LUAD | Female-baised eQTL |
| rs6918887 | chr6:31304356:A:G | - | 0.0524332760418967 | 0.0127060990547669 | LUAD | Female-baised eQTL |
| rs115851658 | chr6:31319333:G:T | - | 0.0570713862595374 | 0.0138111880535674 | LUAD | Female-baised eQTL |
| rs56365848 | chr6:31408900:G:A | - | 0.055085090758681 | 0.0164711984371414 | LUAD | Female-baised eQTL |
| rs72882972 | chr6:31387162:A:T | - | 0.0550344374070251 | 0.0166247147143284 | LUAD | Female-baised eQTL |
| rs72867732 | chr6:31392512:A:G | - | 0.0549946874564141 | 0.0168575218733389 | LUAD | Female-baised eQTL |
| rs142740116 | chr6:31393061:A:G | - | 0.0549946874564141 | 0.0168575218733389 | LUAD | Female-baised eQTL |
| rs72883110 | chr6:31399192:T:C | - | 0.0549946874564141 | 0.0168575218733389 | LUAD | Female-baised eQTL |
| rs146482045 | chr6:31399275:T:G | - | 0.0549946874564141 | 0.0168575218733389 | LUAD | Female-baised eQTL |
| rs2524070 | chr6:31276743:G:A | - | 0.0329277284570896 | 0.0219455758318875 | LUAD | Female-baised eQTL |
| rs2844594 | chr6:31290616:G:A | - | 0.0302715177236758 | 0.0223327361907551 | LUAD | Female-baised eQTL |
| rs2524088 | chr6:31273483:T:C | - | 0.0308139952039124 | 0.0225029078006775 | LUAD | Female-baised eQTL |
| rs9391774 | chr6:31351195:G:A | - | 0.0466254281031471 | 0.0232511355497047 | LUAD | Female-baised eQTL |
| rs56353634 | chr6:31350717:G:A | - | 0.044695618480867 | 0.0283057724916384 | LUAD | Female-baised eQTL |
| rs9391773 | chr6:31350808:G:T | - | 0.044695618480867 | 0.0283057724916384 | LUAD | Female-baised eQTL |
| rs55813549 | chr6:31350869:C:T | - | 0.0445838206392261 | 0.0291728108727749 | LUAD | Female-baised eQTL |
| rs9391846 | chr6:31351504:A:G | - | 0.0445838206392261 | 0.0291728108727749 | LUAD | Female-baised eQTL |
| rs4527750 | chr6:31348259:C:T | - | 0.0438540013251404 | 0.0320002615640529 | LUAD | Female-baised eQTL |
| rs9391841 | chr6:31348943:G:C | - | 0.0438540013251404 | 0.0320002615640529 | LUAD | Female-baised eQTL |
| rs56262493 | chr6:31350430:T:A | - | 0.0438540013251404 | 0.0320002615640529 | LUAD | Female-baised eQTL |
| rs55674503 | chr6:31350509:C:T | - | 0.0438540013251404 | 0.0320002615640529 | LUAD | Female-baised eQTL |
| rs56280537 | chr6:31350543:C:T | - | 0.0438540013251404 | 0.0320002615640529 | LUAD | Female-baised eQTL |
| rs17200628 | chr6:31479985:C:A | - | 0.0517965696609239 | 0.0383683137420125 | LUAD | Female-baised eQTL |
| rs116518228 | chr6:31480875:C:T | - | 0.0517965696609239 | 0.0383683137420125 | LUAD | Female-baised eQTL |
| rs140815160 | chr6:31472668:T:A | - | 0.0516589048302813 | 0.0395641213088378 | LUAD | Female-baised eQTL |
| rs520188 | chr6:19992034:G:A | - | -0.0407416695263554 | 0.0399385964715079 | LUAD | Female-baised eQTL |
| rs28397310 | chr6:31266724:C:T | - | 0.0445192215979833 | 0.0407848238366618 | LUAD | Female-baised eQTL |
| rs2844623 | chr6:31264766:C:T | - | 0.0297273242601993 | 0.0408813384993994 | LUAD | Female-baised eQTL |
| rs142821158 | chr6:31264033:G:A | - | 0.0514032754064132 | 0.0468277419456263 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs114611070 | chr6:27221174:C:T | - | 0.200358199722311 | 0.000361101549181175 | PAAD | Male-baised eQTL |
| rs76456228 | chr6:27230556:A:T | - | 0.200358199722311 | 0.000361101549181175 | PAAD | Male-baised eQTL |
| rs79047440 | chr6:27116329:C:T | - | 0.200064455885534 | 0.000371204869938914 | PAAD | Male-baised eQTL |
| rs79415651 | chr6:27118230:C:A | - | 0.200064455885534 | 0.000371204869938914 | PAAD | Male-baised eQTL |
| rs75926030 | chr6:27125728:C:T | - | 0.200064455885534 | 0.000371204869938914 | PAAD | Male-baised eQTL |
| rs77329513 | chr6:27137727:G:A | - | 0.200064455885534 | 0.000371204869938914 | PAAD | Male-baised eQTL |
| rs147102735 | chr6:27177251:T:C | - | 0.200064455885534 | 0.000371204869938914 | PAAD | Male-baised eQTL |
| rs77865139 | chr6:27076113:A:G | - | 0.199902329670629 | 0.000384820218408258 | PAAD | Male-baised eQTL |
| rs75339846 | chr6:27368002:T:A | - | 0.189082124211522 | 0.000843210250928364 | PAAD | Male-baised eQTL |
| rs116073868 | chr6:27430352:C:T | - | 0.189082124211522 | 0.000843210250928364 | PAAD | Male-baised eQTL |
| rs75508587 | chr6:27374129:C:T | - | 0.176310773274199 | 0.0025868466464489 | PAAD | Male-baised eQTL |
| rs9296138 | chr6:34906042:G:T | - | 0.175594580379776 | 0.011033240288722 | SARC | Male-baised eQTL |
| rs1074521 | chr6:15702385:T:C | - | -0.0541954396018766 | 7.79377564267095e-05 | LUSC | Male-baised eQTL |
| rs4282401 | chr6:15719693:T:C | - | -0.052482861031598 | 0.000145680621269584 | LUSC | Male-baised eQTL |
| rs17641827 | chr6:16156888:C:G | - | 0.0957452448102983 | 0.00507330086521581 | LUAD | Male-baised eQTL |
| rs77926209 | chr6:26245338:C:A | - | 0.100110570720903 | 0.0333659902651278 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000111913 |
| CpG Site: cg13175329 | |
| Position to Gene: gene | |
| Male Effect: -0.42477920384734 | |
| Female Effect: - | |
 | Gene ID: ENSG00000111913 |
| CpG Site: cg08576643 | |
| Position to Gene: gene | |
| Male Effect: 0.112991338743856 | |
| Female Effect: - | |
 | Gene ID: ENSG00000111913 |
| CpG Site: cg06636971 | |
| Position to Gene: gene | |
| Male Effect: 0.0986496449004036 | |
| Female Effect: - | |
 | Gene ID: ENSG00000111913 |
| CpG Site: cg19936032 | |
| Position to Gene: gene | |
| Male Effect: 0.10004232924306 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg13175329 | chr6:25034845 | gene | -0.42477920384734 | 4.89737002448923e-05 | -0.4429550824417351 | 5.3171009146174136e-08 | THCA |
| cg08576643 | chr6:24911317 | gene | 0.112991338743856 | 2.60003634196907e-07 | 0.3979799195549543 | 6.989700391816332e-10 | LUAD |
| cg06636971 | chr6:24911325 | gene | 0.0986496449004036 | 5.14371460262705e-06 | 0.36072224683401527 | 2.9521391038016515e-08 | LUAD |
| cg19936032 | chr6:24911186 | gene | 0.10004232924306 | 1.29522139132969e-05 | 0.35730155967979177 | 4.0675394298957624e-08 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of FAM65B |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
