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Center for Computational Systems Medicine
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Gene summary

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Gene structure and Gene expression level

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Sex-biased somatic mutation

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DNA methylation with beta values in gene

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Exon skipping events with PSI in TCGA

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RNA A-to-I editing events in TCGA

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Sex-biased TF-Gene network of gene

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Sex-biased RBP-ES network of gene

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Sex-biased CeRNA regulation of gene

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Sex-biased eQTL regulation of gene

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Sex-biased eQTM regulation of gene

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Sex-biased sQTL regulation of gene

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Sex-biased sQTM regulation of gene

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Related disease information of gene

Gene: ENSG00000110680

Summary for CALCA

check button Gene summary

Gene informationEnsembl ID

ENSG00000110680

Gene symbol

CALCA

Gene namecalcitonin related polypeptide alpha
HGNC

1437

Entrez ID

796

Gene typeprotein_coding
SynonymsCALCA|CGRP|CGRP-alpha
UniProtAcc

"P01258|P06881"


check buttonDrugs associated with this gene(DrugBank).
Gene IDGene SymbolDrug IDDrug NameDrug Type
ENSG00000110680CALCADB04869OlcegepantSmallMoleculeDrug
ENSG00000110680CALCADB12228TelcagepantSmallMoleculeDrug
ENSG00000110680CALCADB14040EptinezumabBiotechDrug
ENSG00000110680CALCADB14041FremanezumabBiotechDrug
ENSG00000110680CALCADB14042GalcanezumabBiotechDrug

check buttonCancer therapeutic drugs associated with this gene(NCI).
Gene IDGene NameDrug IDDrug NameDrug TypeCancer

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Structure and expression level for CALCA

check buttonAS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.
UCSC result

check buttonLandscape of gene expressions across multiple cancer types.
gene expression analysis

check buttonDifferentially expressed gene analysis between tumor male and tumor female samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
CALCA1.95e+012.97e+003.05e-019.75e+001.86e-226.14e-20KIRC
CALCA1.08e+021.23e+002.98e-014.14e+003.48e-054.67e-03THCA
CALCA2.65e+011.27e+002.99e-014.25e+002.11e-051.11e-03LUSC
CALCA3.20e+01-2.77e+003.55e-01-7.81e+005.63e-153.97e-12STAD
CALCA3.48e+01-1.30e+003.73e-01-3.48e+005.07e-045.52e-03SARC
CALCA2.17e+014.28e+008.49e-015.04e+004.70e-072.78e-04ESCA

check buttonDifferentially expressed gene analysis between tumor male and normal male samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
CALCA3.07e+02-2.62e+006.11e-01-4.29e+001.81e-053.29e-05KIRC
CALCA4.10e+013.55e+006.10e-015.81e+006.17e-093.20e-08COAD
CALCA1.38e+023.24e+001.03e+003.15e+001.62e-035.18e-03CHOL

check buttonDifferentially expressed gene analysis between tumor female and normal female samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
CALCA6.39e+013.52e+001.23e+002.85e+004.33e-031.78e-02STAD
CALCA1.24e+02-7.03e+009.41e-01-7.47e+007.82e-149.89e-12KIRP

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Sex-biased somatic mutation for CALCA

∗For more information on exon skipping events please check the ExonskipDB database.
Gene IDCancer TypeHugo SymbolMaleFemalepvalorci.upci.lowadjPval

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DNA methylation with beta values for CALCA

check buttonLandscape of DNA methylation across multiple cancer types.
methylation heatmap

check buttonDifferentially expressed CpG sites between male tumor and female tumor patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
BRCAcg22863523chr11:14973655CGI:chr11:14973582-14974362promoter2.24e-014.29e-01-2.67e+007.56e-032.40e-02-2.06e-01
BRCAcg11697588chr11:14973685CGI:chr11:14973582-14974362promoter3.19e-015.68e-01-3.18e+001.49e-031.17e-02-2.49e-01
BRCAcg16245265chr11:14973687CGI:chr11:14973582-14974362promoter2.57e-014.91e-01-2.69e+007.24e-032.36e-02-2.34e-01
BRCAcg08929188chr11:14973776CGI:chr11:14973582-14974362promoter2.33e-013.75e-01-2.11e+003.46e-024.34e-02-1.42e-01
SARCcg25783352chr11:14971963CGI:chr11:14971906-14972115promoter,gene body3.08e-012.05e-013.22e+001.30e-034.29e-031.03e-01
SARCcg09068492chr11:14972112CGI:chr11:14971906-14972115promoter,gene body2.91e-011.89e-012.08e+003.75e-024.22e-021.02e-01
SARCcg26833169chr11:14972499CGI:chr11:14971906-14972115promoter3.05e-012.04e-013.43e+006.04e-042.34e-031.01e-01
SARCcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter5.15e-013.96e-014.02e+005.75e-053.14e-041.18e-01
SARCcg06796866chr11:14973098CGI:chr11:14973582-14974362promoter5.15e-013.62e-014.38e+001.20e-057.41e-051.53e-01
MESOcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter5.68e-014.01e-012.91e+003.64e-031.46e-021.66e-01
MESOcg11697588chr11:14973685CGI:chr11:14973582-14974362promoter1.22e-012.76e-01-2.82e+004.85e-031.80e-02-1.54e-01
MESOcg16245265chr11:14973687CGI:chr11:14973582-14974362promoter9.56e-022.30e-01-2.35e+001.88e-023.77e-02-1.35e-01
CHOLcg22085702chr11:14972676CGI:chr11:14971906-14972115promoter5.10e-014.07e-012.36e+001.85e-023.14e-021.03e-01

check buttonDifferentially expressed CpG sites between male tumor and male normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
KIRCcg25943588chr11:14972367CGI:chr11:14971906-14972115promoter1.88e-017.13e-024.90e+009.41e-073.45e-061.16e-01
KIRCcg11596897chr11:14973209CGI:chr11:14973582-14974362promoter4.67e-015.81e-01-3.67e+002.38e-044.38e-04-1.14e-01
HNSCcg08176386chr11:14973347CGI:chr11:14973582-14974362promoter1.29e-012.60e-024.00e+006.34e-051.77e-041.04e-01
HNSCcg01971122chr11:14972383CGI:chr11:14971906-14972115promoter2.89e-011.79e-014.33e+001.52e-055.38e-051.11e-01
HNSCcg05093325chr11:14973341CGI:chr11:14973582-14974362promoter2.41e-011.38e-013.75e+001.75e-044.15e-041.03e-01
HNSCcg18470144chr11:14973443CGI:chr11:14973582-14974362promoter4.64e-013.12e-014.86e+001.15e-066.53e-061.52e-01
HNSCcg07529966chr11:14973720CGI:chr11:14973582-14974362promoter2.10e-017.81e-023.93e+008.64e-052.29e-041.32e-01
LUSCcg27413462chr11:14972320CGI:chr11:14971906-14972115UTR,promoter,exon,gene body2.94e-011.38e-012.91e+003.60e-036.40e-031.56e-01
LUSCcg25943588chr11:14972367CGI:chr11:14971906-14972115promoter3.31e-011.17e-013.26e+001.10e-032.76e-032.14e-01
LUSCcg11153872chr11:14973596CGI:chr11:14973582-14974362promoter1.36e-012.96e-024.07e+004.71e-055.50e-041.06e-01
LUSCcg08176386chr11:14973347CGI:chr11:14973582-14974362promoter1.26e-012.45e-022.70e+006.86e-031.04e-021.02e-01
LUSCcg12083965chr11:14973592CGI:chr11:14973582-14974362promoter1.32e-011.88e-023.97e+007.17e-056.15e-041.13e-01
LUSCcg22863523chr11:14973655CGI:chr11:14973582-14974362promoter1.90e-013.13e-023.58e+003.38e-041.31e-031.59e-01
LUSCcg09188980chr11:14971832CGI:chr11:14971906-14972115promoter,gene body3.45e-011.85e-012.92e+003.55e-036.33e-031.60e-01
LUSCcg25783352chr11:14971963CGI:chr11:14971906-14972115promoter,gene body3.28e-011.68e-012.93e+003.39e-036.12e-031.60e-01
LUSCcg14348532chr11:14972016CGI:chr11:14971906-14972115promoter,gene body2.62e-011.09e-012.71e+006.76e-031.03e-021.53e-01
LUSCcg09068492chr11:14972112CGI:chr11:14971906-14972115promoter,gene body3.62e-011.50e-012.68e+007.26e-031.08e-022.11e-01
LUSCcg22183706chr11:14972272CGI:chr11:14971906-14972115UTR,promoter,exon,gene body3.41e-011.35e-012.92e+003.50e-036.26e-032.07e-01
LUSCcg17072805chr11:14972323CGI:chr11:14971906-14972115UTR,promoter,exon,gene body3.67e-012.12e-012.89e+003.88e-036.76e-031.55e-01
LUSCcg01971122chr11:14972383CGI:chr11:14971906-14972115promoter2.87e-011.76e-012.55e+001.08e-021.47e-021.11e-01
LUSCcg02077276chr11:14972431CGI:chr11:14971906-14972115promoter4.32e-012.73e-012.43e+001.51e-021.91e-021.59e-01
LUSCcg24117998chr11:14972457CGI:chr11:14971906-14972115promoter4.14e-012.79e-012.56e+001.05e-021.44e-021.35e-01
LUSCcg26833169chr11:14972499CGI:chr11:14971906-14972115promoter3.24e-011.79e-012.74e+006.21e-039.61e-031.45e-01
LUSCcg01995938chr11:14972584CGI:chr11:14971906-14972115promoter3.64e-012.36e-012.35e+001.90e-022.29e-021.28e-01
LUSCcg14106660chr11:14972633CGI:chr11:14971906-14972115promoter4.40e-012.93e-012.63e+008.58e-031.23e-021.46e-01
LUSCcg12904004chr11:14972652CGI:chr11:14971906-14972115promoter5.49e-014.32e-012.65e+008.01e-031.17e-021.18e-01
LUSCcg22085702chr11:14972676CGI:chr11:14971906-14972115promoter4.80e-013.01e-014.05e+005.21e-055.63e-041.79e-01
LUSCcg13491234chr11:14972684CGI:chr11:14971906-14972115promoter6.52e-014.65e-014.08e+004.43e-055.44e-041.87e-01
LUSCcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter5.32e-013.76e-013.34e+008.39e-042.31e-031.56e-01
LUSCcg24442913chr11:14973060CGI:chr11:14973582-14974362promoter6.36e-014.60e-013.39e+007.08e-042.07e-031.76e-01
LUSCcg06796866chr11:14973098CGI:chr11:14973582-14974362promoter5.22e-012.94e-013.25e+001.17e-032.89e-032.28e-01
LUSCcg11596897chr11:14973209CGI:chr11:14973582-14974362promoter5.05e-013.52e-013.05e+002.31e-034.62e-031.52e-01
LUSCcg05397812chr11:14973301CGI:chr11:14973582-14974362promoter3.27e-011.50e-012.38e+001.74e-022.13e-021.77e-01
LUSCcg05093325chr11:14973341CGI:chr11:14973582-14974362promoter2.43e-011.13e-013.25e+001.17e-032.89e-031.30e-01
LUSCcg18470144chr11:14973443CGI:chr11:14973582-14974362promoter3.91e-012.86e-012.08e+003.73e-023.94e-021.05e-01
LUSCcg26676559chr11:14973621CGI:chr11:14973582-14974362promoter2.80e-018.55e-022.47e+001.36e-021.76e-021.94e-01
LUSCcg00332249chr11:14973712CGI:chr11:14973582-14974362promoter1.93e-016.72e-022.49e+001.27e-021.67e-021.26e-01
BLCAcg22183706chr11:14972272CGI:chr11:14971906-14972115UTR,promoter,exon,gene body2.85e-011.15e-012.13e+003.33e-023.64e-021.71e-01
BLCAcg14106660chr11:14972633CGI:chr11:14971906-14972115promoter3.86e-012.63e-012.46e+001.40e-021.85e-021.24e-01
BLCAcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter4.73e-013.54e-012.67e+007.69e-031.15e-021.19e-01
BLCAcg16245265chr11:14973687CGI:chr11:14973582-14974362promoter1.92e-015.63e-022.10e+003.61e-023.89e-021.35e-01
LIHCcg26676559chr11:14973621CGI:chr11:14973582-14974362promoter2.67e-011.11e-012.84e+004.53e-036.04e-031.56e-01
ESCAcg12904004chr11:14972652CGI:chr11:14971906-14972115promoter5.75e-014.38e-012.43e+001.50e-023.82e-021.37e-01
ESCAcg24442913chr11:14973060CGI:chr11:14973582-14974362promoter6.62e-015.34e-012.10e+003.53e-024.53e-021.28e-01
ESCAcg11596897chr11:14973209CGI:chr11:14973582-14974362promoter5.29e-014.02e-012.25e+002.42e-024.19e-021.27e-01
ESCAcg05397812chr11:14973301CGI:chr11:14973582-14974362promoter2.90e-011.37e-012.04e+004.18e-024.72e-021.53e-01
ESCAcg10467022chr11:14973437CGI:chr11:14973582-14974362promoter3.59e-012.25e-012.20e+002.75e-024.30e-021.35e-01
ESCAcg18470144chr11:14973443CGI:chr11:14973582-14974362promoter4.56e-013.37e-012.01e+004.49e-024.81e-021.19e-01
ESCAcg26676559chr11:14973621CGI:chr11:14973582-14974362promoter5.45e-013.13e-012.06e+003.89e-024.64e-022.32e-01
CHOLcg22085702chr11:14972676CGI:chr11:14971906-14972115promoter4.07e-012.97e-011.99e+004.65e-024.65e-021.10e-01
CHOLcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter6.01e-014.70e-012.21e+002.70e-023.50e-021.31e-01
CHOLcg24442913chr11:14973060CGI:chr11:14973582-14974362promoter6.74e-015.47e-012.65e+007.96e-031.92e-021.26e-01
CHOLcg06796866chr11:14973098CGI:chr11:14973582-14974362promoter6.35e-014.52e-012.73e+006.38e-031.82e-021.83e-01

check buttonDifferentially expressed CpG sites between female tumor and female normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
BRCAcg27413462chr11:14972320CGI:chr11:14971906-14972115UTR,promoter,exon,gene body2.47e-011.06e-018.30e+001.05e-164.35e-161.41e-01
BRCAcg25943588chr11:14972367CGI:chr11:14971906-14972115promoter2.18e-017.83e-028.95e+003.66e-191.85e-181.39e-01
BRCAcg22863523chr11:14973655CGI:chr11:14973582-14974362promoter2.24e-015.80e-027.41e+001.23e-134.04e-131.66e-01
BRCAcg25783352chr11:14971963CGI:chr11:14971906-14972115promoter,gene body2.39e-011.36e-017.67e+001.74e-146.11e-141.03e-01
BRCAcg06295856chr11:14972096CGI:chr11:14971906-14972115promoter,gene body2.09e-019.60e-029.04e+001.55e-198.04e-191.13e-01
BRCAcg09068492chr11:14972112CGI:chr11:14971906-14972115promoter,gene body2.40e-011.26e-016.34e+002.27e-105.81e-101.14e-01
BRCAcg22183706chr11:14972272CGI:chr11:14971906-14972115UTR,promoter,exon,gene body2.92e-018.41e-021.09e+019.17e-281.03e-262.08e-01
BRCAcg17072805chr11:14972323CGI:chr11:14971906-14972115UTR,promoter,exon,gene body3.22e-011.77e-018.41e+004.16e-171.78e-161.45e-01
BRCAcg02077276chr11:14972431CGI:chr11:14971906-14972115promoter3.31e-012.06e-018.24e+001.70e-166.95e-161.25e-01
BRCAcg24117998chr11:14972457CGI:chr11:14971906-14972115promoter3.50e-012.31e-017.98e+001.50e-155.70e-151.19e-01
BRCAcg14106660chr11:14972633CGI:chr11:14971906-14972115promoter4.31e-012.32e-011.14e+012.96e-304.45e-291.99e-01
BRCAcg12904004chr11:14972652CGI:chr11:14971906-14972115promoter5.37e-014.22e-018.49e+002.12e-179.30e-171.14e-01
BRCAcg22085702chr11:14972676CGI:chr11:14971906-14972115promoter4.74e-013.00e-011.20e+015.00e-331.08e-311.74e-01
BRCAcg13491234chr11:14972684CGI:chr11:14971906-14972115promoter6.28e-014.50e-011.20e+014.65e-331.02e-311.78e-01
BRCAcg07238401chr11:14972851CGI:chr11:14973582-14974362promoter4.40e-013.36e-018.36e+006.19e-172.62e-161.04e-01
BRCAcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter5.28e-014.12e-018.14e+003.94e-161.57e-151.16e-01
BRCAcg24442913chr11:14973060CGI:chr11:14973582-14974362promoter6.43e-014.53e-011.17e+011.63e-312.87e-301.89e-01
BRCAcg06796866chr11:14973098CGI:chr11:14973582-14974362promoter4.60e-013.24e-017.14e+009.07e-132.79e-121.35e-01
BRCAcg11596897chr11:14973209CGI:chr11:14973582-14974362promoter5.21e-013.98e-018.18e+002.77e-161.11e-151.23e-01
BRCAcg26676559chr11:14973621CGI:chr11:14973582-14974362promoter3.12e-011.04e-013.49e+004.82e-046.60e-042.08e-01
BRCAcg11697588chr11:14973685CGI:chr11:14973582-14974362promoter3.19e-011.36e-017.58e+003.39e-141.16e-131.83e-01
BRCAcg16245265chr11:14973687CGI:chr11:14973582-14974362promoter2.57e-017.79e-027.32e+002.40e-137.72e-131.79e-01
BRCAcg08929188chr11:14973776CGI:chr11:14973582-14974362promoter2.33e-018.89e-027.59e+003.24e-141.11e-131.44e-01
LUADcg09188980chr11:14971832CGI:chr11:14971906-14972115promoter,gene body3.48e-011.90e-013.60e+003.12e-041.55e-031.59e-01
LUADcg14348532chr11:14972016CGI:chr11:14971906-14972115promoter,gene body2.20e-019.51e-023.77e+001.61e-041.08e-031.25e-01
LUADcg02077276chr11:14972431CGI:chr11:14971906-14972115promoter3.79e-012.43e-013.19e+001.44e-034.07e-031.36e-01
LUADcg14106660chr11:14972633CGI:chr11:14971906-14972115promoter4.13e-012.62e-013.34e+008.38e-042.84e-031.51e-01
LUADcg07238401chr11:14972851CGI:chr11:14973582-14974362promoter4.66e-013.56e-013.29e+001.01e-033.21e-031.10e-01
LUADcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter4.91e-013.62e-013.46e+005.46e-042.17e-031.29e-01
LUADcg18470144chr11:14973443CGI:chr11:14973582-14974362promoter3.80e-012.76e-012.23e+002.58e-023.10e-021.04e-01
LUADcg00332249chr11:14973712CGI:chr11:14973582-14974362promoter1.79e-017.45e-022.31e+002.11e-022.69e-021.04e-01
COADcg24117998chr11:14972457CGI:chr11:14971906-14972115promoter3.26e-012.04e-012.03e+004.24e-024.43e-021.22e-01
COADcg26833169chr11:14972499CGI:chr11:14971906-14972115promoter2.62e-011.34e-012.62e+008.78e-031.43e-021.28e-01
COADcg11596897chr11:14973209CGI:chr11:14973582-14974362promoter2.99e-011.94e-012.64e+008.37e-031.38e-021.05e-01
COADcg18470144chr11:14973443CGI:chr11:14973582-14974362promoter3.33e-012.22e-012.14e+003.27e-023.69e-021.11e-01
BLCAcg11153872chr11:14973596CGI:chr11:14973582-14974362promoter1.51e-015.00e-022.48e+001.30e-022.06e-021.01e-01
BLCAcg08929188chr11:14973776CGI:chr11:14973582-14974362promoter2.81e-011.21e-012.12e+003.43e-023.87e-021.60e-01
LIHCcg25783352chr11:14971963CGI:chr11:14971906-14972115promoter,gene body3.25e-011.92e-012.31e+002.10e-022.50e-021.33e-01
LIHCcg26833169chr11:14972499CGI:chr11:14971906-14972115promoter2.41e-011.41e-012.20e+002.77e-023.12e-021.01e-01
LIHCcg14106660chr11:14972633CGI:chr11:14971906-14972115promoter3.90e-012.86e-012.02e+004.34e-024.46e-021.04e-01
LIHCcg22085702chr11:14972676CGI:chr11:14971906-14972115promoter4.46e-013.14e-013.98e+006.79e-052.87e-041.32e-01
LIHCcg13491234chr11:14972684CGI:chr11:14971906-14972115promoter6.38e-015.21e-013.38e+007.21e-041.75e-031.17e-01
LIHCcg05061471chr11:14973015CGI:chr11:14973582-14974362promoter6.03e-014.62e-014.27e+001.99e-051.14e-041.41e-01
KIRPcg25783352chr11:14971963CGI:chr11:14971906-14972115promoter,gene body2.92e-011.48e-012.83e+004.60e-031.01e-021.44e-01
KIRPcg14348532chr11:14972016CGI:chr11:14971906-14972115promoter,gene body1.96e-018.57e-023.06e+002.25e-036.39e-031.10e-01
KIRPcg09068492chr11:14972112CGI:chr11:14971906-14972115promoter,gene body2.37e-011.05e-012.39e+001.68e-022.38e-021.32e-01

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Exon skipping events with PSI in TCGA for CALCA

∗Please access ExonSkipDB for exon skipping annotation.
check buttonDifferentially expressed exon skipping events between male tumor and female tumor patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between male tumor and male normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between female tumor and female normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

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RNA A-to-I editing events in TCGA for CALCA

∗Please access CAeditome for RNA editing annotation.
check buttonDifferentially expressed RNA editing events between male tumor and female tumor patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonDifferentially expressed RNA editing events between male tumor and male normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonDifferentially expressed RNA editing events between female tumor and female normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonProtein coding RNA editing(s).
Editing PositionVariant TypeGene SymbolTranscript IDNTchangeAAchange

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Sex-biased TF-Gene network for CALCA

check buttonTFs related to CALCA.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
Cancer TypeTFTarget GeneMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType

check buttonCALCA related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for CALCA

check buttonRBPs related to ES in CALCA.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
Cancer TypeRBPTarget ESMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType

check buttonCALCA related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

check buttonSex-biased CeRNA regulation of gene.
Gene IDceRNA(lncRNA-miRNA-mRNA)GroupCancer Type

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Sex-biased eQTL regulation of gene

check buttonSex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
eQTLDescription

check buttonMale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type
rs72857966chr11:9129005:G:C-0.05572380732088020.00113674655085667THCAFemale-baised eQTL
rs12366113chr11:9134140:G:A-0.03743082039586390.0217651706069556THCAFemale-baised eQTL
rs72857991chr11:9160471:T:A-0.03571466165526780.0363584877717754THCAFemale-baised eQTL
rs72857993chr11:9160493:C:T-0.03571466165526780.0363584877717754THCAFemale-baised eQTL
rs11042197chr11:9151505:G:C-0.03571160007170220.0367249570353471THCAFemale-baised eQTL
rs113681327chr11:9152923:G:A-0.03552922226714010.0388416971738622THCAFemale-baised eQTL
rs72857989chr11:9158701:C:T-0.03511157207564260.044052060183713THCAFemale-baised eQTL
rs11603682chr11:19516305:C:G-0.07566183645207150.0374530675690378SARCFemale-baised eQTL
rs7479130chr11:19302968:C:T-0.1145225889526950.00219861869720867LUSCFemale-baised eQTL
rs74711269chr11:19309381:T:A-0.1145225889526950.00219861869720867LUSCFemale-baised eQTL
rs17500922chr11:19313735:C:T-0.1145225889526950.00219861869720867LUSCFemale-baised eQTL
rs17592922chr11:19359827:C:T-0.1088240154249540.00407388308909796LUSCFemale-baised eQTL
rs16936547chr11:19331069:T:C-0.09901558900684830.0111863411850338LUSCFemale-baised eQTL
rs58147615chr11:19311933:G:C-0.09904691148545880.0112360202814247LUSCFemale-baised eQTL
rs1393697chr11:19319234:C:T-0.09904691148545880.0112360202814247LUSCFemale-baised eQTL
rs73428641chr11:19355286:G:T-0.09494955767105840.0170205363342966LUSCFemale-baised eQTL
rs7948272chr11:19356202:C:T-0.09494955767105840.0170205363342966LUSCFemale-baised eQTL
rs56355354chr11:19335812:C:G-0.09488771476127070.017022702710736LUSCFemale-baised eQTL
rs73428625chr11:19349155:C:T-0.0949834210464860.0171020810866135LUSCFemale-baised eQTL
rs17501813chr11:19364427:C:T-0.09106534807346950.0241213249435103LUSCFemale-baised eQTL
rs17593306chr11:19369635:A:G-0.09106534807346950.0241213249435103LUSCFemale-baised eQTL
rs73428676chr11:19369726:T:C-0.09106534807346950.0241213249435103LUSCFemale-baised eQTL
rs58588763chr11:19366612:A:C-0.09110088195193410.0242293653270624LUSCFemale-baised eQTL
rs200885391chr11:19297198:T:A--0.08952617855362680.0246410925387773LUSCFemale-baised eQTL
rs7939122chr11:19297200:T:A--0.08952617855362680.0246410925387773LUSCFemale-baised eQTL
rs16936551chr11:19336484:A:T-0.08746641698905580.0329809415771613LUSCFemale-baised eQTL
rs10734274chr11:19316482:C:T--0.08268569218983520.0460975816821447LUSCFemale-baised eQTL
rs11820989chr11:9873846:C:T-0.07504857911078477.12745420834047e-05LUADFemale-baised eQTL
rs10500710chr11:9874618:C:T-0.06913099613781628.94621619962211e-05LUADFemale-baised eQTL
rs1546543chr11:9879347:A:G-0.06905566932713940.000267870557336618LUADFemale-baised eQTL
rs10500711chr11:9879788:A:G-0.06905566932713940.000267870557336618LUADFemale-baised eQTL
rs80078966chr11:9880858:A:G-0.06904509000374290.000270756044219849LUADFemale-baised eQTL
rs74469856chr11:9876039:G:A-0.06761433541418950.000314755785173204LUADFemale-baised eQTL
rs901395chr11:10986497:T:C--0.05583259165509380.000919740893292826LUADFemale-baised eQTL
rs78352842chr11:10987126:G:A-0.05583259165509370.000919740893292826LUADFemale-baised eQTL
rs79859479chr11:10989986:G:T-0.05582581616795610.000926882457770476LUADFemale-baised eQTL
rs79879343chr11:10987611:C:T-0.05456249894456010.00122036243907749LUADFemale-baised eQTL
rs1872696chr11:10989157:A:C--0.05455551077722960.00123047800890367LUADFemale-baised eQTL
rs2403379chr11:10992480:A:C--0.05455551077722960.00123047800890367LUADFemale-baised eQTL
rs10770156chr11:10997883:C:T--0.0533472762885680.0015939373820684LUADFemale-baised eQTL
rs7123551chr11:23861809:G:A-0.05026975838755240.00229330871613733LUADFemale-baised eQTL
rs4757257chr11:12188212:A:G-0.04932047610065170.00252224259472796LUADFemale-baised eQTL
rs6484588chr11:10988674:A:G--0.05105589162333870.00264824002063426LUADFemale-baised eQTL
rs78457714chr11:12181584:C:A-0.05241676215631960.00313358747395405LUADFemale-baised eQTL
rs2345352chr11:6687022:A:G-0.04197211374897070.00413390078905524LUADFemale-baised eQTL
rs28439532chr11:24186466:C:T-0.05232703457370740.00443526277133426LUADFemale-baised eQTL
rs73416226chr11:12188014:C:T-0.04863316313932060.00603758410963677LUADFemale-baised eQTL
rs17477837chr11:12194701:G:A-0.04812592725441420.00607840059904032LUADFemale-baised eQTL
rs2345353chr11:6687225:G:A-0.04024759756081950.00622922998892397LUADFemale-baised eQTL
rs7117762chr11:12622054:G:C--0.02875161480380580.0115656886243949LUADFemale-baised eQTL
rs7104067chr11:12622323:A:G--0.02875161480380580.0115656886243949LUADFemale-baised eQTL
rs4757258chr11:12193825:T:A--0.04119496012733590.0131373155448453LUADFemale-baised eQTL
rs11821046chr11:7744337:G:A-0.04902452206121010.0139266845355418LUADFemale-baised eQTL
rs7110982chr11:24255188:A:T-0.0488812992070840.0140646491409537LUADFemale-baised eQTL
rs11022775chr11:13352217:C:T-0.03856582904894030.0163973711666215LUADFemale-baised eQTL
rs7123629chr11:9657220:C:G--0.04379333298013220.0166840923315186LUADFemale-baised eQTL
rs60271535chr11:8183338:T:G-0.04479306451870.0187451175528933LUADFemale-baised eQTL
rs74887500chr11:7745784:T:C-0.04649544025061060.019057594194345LUADFemale-baised eQTL
rs6484590chr11:10990254:A:C--0.03738760772381190.0191815822991765LUADFemale-baised eQTL
rs73399250chr11:6686735:G:A-0.03443084485892230.0201232167074983LUADFemale-baised eQTL
rs1111585chr11:6679371:G:T-0.04679848410287660.0213483209353744LUADFemale-baised eQTL
rs12796933chr11:13181360:G:A-0.03707444558250260.0245304229183346LUADFemale-baised eQTL
rs12797657chr11:13181132:T:A-0.0370656928029090.0246833905398452LUADFemale-baised eQTL
rs12797679chr11:13181163:T:G-0.03705633652824250.0248442291217863LUADFemale-baised eQTL
rs12271128chr11:6684290:T:G-0.03307474205129480.0258000281777256LUADFemale-baised eQTL
rs111658627chr11:6684523:A:C-0.0331999824769520.0259018347819142LUADFemale-baised eQTL
rs12796093chr11:13181122:C:T-0.03649984712714180.027579489400219LUADFemale-baised eQTL
rs112286068chr11:6684483:T:C-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs9651659chr11:6684636:C:G-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs7129959chr11:6684736:G:C-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs1911276chr11:6684847:T:C-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs7130871chr11:6685475:G:A-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs7131011chr11:6685576:G:T-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs7120504chr11:6685577:T:C-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs7120498chr11:6685758:A:G-0.03269706091690530.0281313819965039LUADFemale-baised eQTL
rs7126152chr11:6684022:G:A-0.03269110889795660.0283058626816365LUADFemale-baised eQTL
rs4757259chr11:12193999:T:C--0.03974761727036760.0292447822860846LUADFemale-baised eQTL
rs6486099chr11:13175491:T:C-0.03580307397357550.0299256617718848LUADFemale-baised eQTL
rs7933677chr11:8692033:T:C-0.03799576438626380.0323878322684649LUADFemale-baised eQTL
rs59801722chr11:13174617:C:T-0.03530915584772920.0324937040970729LUADFemale-baised eQTL
rs7103727chr11:6685600:G:A-0.03198012128449490.0327018885781273LUADFemale-baised eQTL
rs11027786chr11:24235879:C:T-0.04288119728643080.0330612364332838LUADFemale-baised eQTL
rs10734643chr11:9311393:A:G--0.03925879388859310.0353753825281813LUADFemale-baised eQTL
rs2468638chr11:23063355:A:G--0.04419172531461620.035698657980469LUADFemale-baised eQTL
rs16912321chr11:13174658:A:G-0.03479027819805870.0358970933665614LUADFemale-baised eQTL
rs12796394chr11:13181293:C:T-0.03476140233940810.0363137803370535LUADFemale-baised eQTL
rs12801840chr11:13181664:A:G-0.03476140233940810.0363137803370535LUADFemale-baised eQTL
rs11828452chr11:13182114:G:A-0.03476140233940810.0363137803370535LUADFemale-baised eQTL
rs7935240chr11:13182823:T:C-0.03476140233940810.0363137803370535LUADFemale-baised eQTL
rs6486101chr11:13183287:G:A-0.03476140233940810.0363137803370535LUADFemale-baised eQTL
rs10743101chr11:9299852:A:G--0.03874165603886050.037550992271615LUADFemale-baised eQTL
rs77201836chr11:12411951:T:C-0.05121543692298780.0380204167377981LUADFemale-baised eQTL
rs11027791chr11:24239961:C:T-0.04187852290723330.0381451945778564LUADFemale-baised eQTL
rs1443047chr11:24236541:G:A-0.04186466357809850.0383346505790067LUADFemale-baised eQTL
rs12270316chr11:24238127:A:G-0.04186466357809850.0383346505790067LUADFemale-baised eQTL
rs2270955chr11:8695421:T:A-0.03757601993074350.0387378550134317LUADFemale-baised eQTL
rs12796730chr11:13181254:G:A-0.03425716249398350.0399445531736492LUADFemale-baised eQTL
rs11828460chr11:13182203:G:A-0.03425716249398350.0399445531736492LUADFemale-baised eQTL
rs6485549chr11:12178863:A:T--0.03763181183284140.0410395657239565LUADFemale-baised eQTL
rs9215chr11:9280714:A:G--0.03805131812019460.0416746726981404LUADFemale-baised eQTL
rs11022776chr11:13352416:C:G-0.03605438420068290.0417489062617678LUADFemale-baised eQTL
rs4622264chr11:9286771:A:G--0.03804068309427790.0419213138851799LUADFemale-baised eQTL
rs4351820chr11:9286872:T:C--0.03804068309427790.0419213138851799LUADFemale-baised eQTL
rs58852267chr11:8378372:G:C-0.03872178008653090.0436025555631855LUADFemale-baised eQTL
rs60843933chr11:8378388:C:T-0.03872178008653090.0436025555631855LUADFemale-baised eQTL
rs10840378chr11:10251581:C:T-0.02851439857969660.0476591336417216LUADFemale-baised eQTL

check buttonFemale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type
rs77513912chr11:7823296:A:G-0.2937141611596793.38294996517731e-08SARCMale-baised eQTL
rs76948726chr11:7823569:G:A-0.2937141611596793.38294996517731e-08SARCMale-baised eQTL
rs1482794chr11:7825976:T:C-0.2937141611596793.38294996517731e-08SARCMale-baised eQTL
rs2885150chr11:7826818:C:G-0.2937141611596793.38294996517731e-08SARCMale-baised eQTL
rs746217chr11:7827050:A:T-0.2937141611596793.38294996517731e-08SARCMale-baised eQTL
rs114752352chr11:7817843:C:A-0.2035828263106118.51328690454909e-05SARCMale-baised eQTL
rs7105029chr11:17740333:G:A--0.2501546797688980.000659790007234213SARCMale-baised eQTL
rs7952123chr11:7733496:C:T-0.1334983573436830.00451057217480587SARCMale-baised eQTL
rs12365410chr11:19857812:G:A-0.1164095712235140.0130983828723231SARCMale-baised eQTL
rs11041779chr11:8172236:C:T--0.1066139616221980.0167561313912062SARCMale-baised eQTL
rs12361114chr11:19857805:T:C-0.1127955624598260.0178238482240444SARCMale-baised eQTL
rs11028059chr11:24605145:A:T-0.1603682788245030.0243681277739168SARCMale-baised eQTL
rs16912297chr11:13166430:C:T-0.1153908799741180.0274093515455509SARCMale-baised eQTL
rs3930849chr11:8134406:C:T-0.09810153882846690.0278344159464116SARCMale-baised eQTL
rs2625324chr11:19863283:C:T--0.103457290650550.0344354440000423SARCMale-baised eQTL
rs11025295chr11:19860440:G:A-0.103457290650550.0344354440000423SARCMale-baised eQTL
rs11025297chr11:19861193:A:G-0.103457290650550.0344354440000423SARCMale-baised eQTL
rs61877272chr11:19861266:A:G-0.103457290650550.0344354440000423SARCMale-baised eQTL
rs61877273chr11:19861518:C:T-0.103457290650550.0344354440000423SARCMale-baised eQTL
rs12361307chr11:19862428:C:T-0.103457290650550.0344354440000423SARCMale-baised eQTL
rs2625314chr11:19869377:G:A--0.1028722819467050.0388617899490451SARCMale-baised eQTL
rs17521571chr11:15733265:G:A-0.1486514985976940.0427101251423222SARCMale-baised eQTL
rs1596293chr11:19875135:T:C--0.1004407683699970.0427615579566847SARCMale-baised eQTL
rs1838055chr11:19849684:G:C-0.100405904683350.0434708901883834SARCMale-baised eQTL
rs2165802chr11:19849766:T:C-0.100405904683350.0434708901883834SARCMale-baised eQTL
rs1443117chr11:19865908:C:G--0.1004557421873710.0437542184657348SARCMale-baised eQTL
rs12280756chr11:15907185:C:T-0.0635174667448062.32567787580074e-05LUSCMale-baised eQTL
rs12293688chr11:15906858:A:T-0.06352103387480242.33245830094966e-05LUSCMale-baised eQTL
rs75460974chr11:23567802:T:C-0.05935642829045868.01892097030297e-05LUSCMale-baised eQTL
rs903213chr11:12323912:C:T--0.05708859098995560.000147106955745508LUSCMale-baised eQTL
rs12287419chr11:23601135:T:G-0.05496924437203790.000293403833814868LUSCMale-baised eQTL
rs12280589chr11:23601376:C:T-0.05496924437203790.000293403833814868LUSCMale-baised eQTL
rs17306705chr11:23602262:T:A-0.05496924437203790.000293403833814868LUSCMale-baised eQTL
rs12289217chr11:23571883:T:C-0.05398031124540160.000395135094897768LUSCMale-baised eQTL
rs10219157chr11:12317618:T:C--0.0518866262888780.000628740592131196LUSCMale-baised eQTL
rs6485643chr11:12302094:C:T--0.05156689975136630.000650962795194949LUSCMale-baised eQTL
rs7128154chr11:23597067:G:A-0.05210082331522860.000667760985695599LUSCMale-baised eQTL
rs11828612chr11:23584197:C:T-0.05210415313453980.000669452922373657LUSCMale-baised eQTL
rs12273586chr11:23585030:A:G-0.05210415313453980.000669452922373657LUSCMale-baised eQTL
rs11827819chr11:23588302:G:C-0.05210415313453980.000669452922373657LUSCMale-baised eQTL
rs11821461chr11:23588606:T:G-0.05210415313453980.000669452922373657LUSCMale-baised eQTL
rs11027384chr11:23589314:C:A-0.05210415313453980.000669452922373657LUSCMale-baised eQTL
rs7127133chr11:23593284:T:G-0.05210415313453980.000669452922373657LUSCMale-baised eQTL
rs112474975chr11:23569809:T:C-0.0521097635068220.000672897962684887LUSCMale-baised eQTL
rs11825557chr11:23604108:G:A-0.05179074642383450.000695504077551315LUSCMale-baised eQTL
rs6485650chr11:12314765:T:C--0.051024645540450.000805573300339971LUSCMale-baised eQTL
rs6485651chr11:12314965:A:G--0.051024645540450.000805573300339971LUSCMale-baised eQTL
rs1948470chr11:12300560:G:A--0.05069854015032050.000826393099545482LUSCMale-baised eQTL
rs1948471chr11:12300576:C:T--0.05070138701045340.000829093392770451LUSCMale-baised eQTL
rs7117872chr11:12302913:C:G--0.05071075622497360.000836165896996014LUSCMale-baised eQTL
rs113856506chr11:23573290:C:A-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs12272765chr11:23573921:A:G-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs7131654chr11:23575035:G:A-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs12272334chr11:23579170:A:T-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs12294440chr11:23580254:T:C-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs12294447chr11:23580305:T:G-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs112210370chr11:23582478:A:G-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs111490332chr11:23582483:G:C-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs12293179chr11:23583437:C:T-0.05121556465785720.000857234678686835LUSCMale-baised eQTL
rs13377324chr11:23604704:C:G-0.0509101670070380.000885967233344518LUSCMale-baised eQTL
rs7108935chr11:23604887:C:T-0.05091532849839670.000890567502798505LUSCMale-baised eQTL
rs1493953chr11:12294344:G:A--0.04984451489734050.00102650009447303LUSCMale-baised eQTL
rs4323849chr11:12309644:G:A--0.0502054132270030.00103466291194318LUSCMale-baised eQTL
rs11607339chr11:5996951:T:C-0.04051128589607840.00103501697998661LUSCMale-baised eQTL
rs11022297chr11:12313161:A:C--0.04938974668842980.00129197380424617LUSCMale-baised eQTL
rs1493951chr11:12294169:C:T--0.04724992803333180.00206680975567522LUSCMale-baised eQTL
rs10741579chr11:12293860:G:C--0.04725453499884690.00207855356207571LUSCMale-baised eQTL
rs1874043chr11:12292340:C:G--0.047259127693220.00209054471278808LUSCMale-baised eQTL
rs10734192chr11:12296789:A:G--0.0465288793994850.00254739522247839LUSCMale-baised eQTL
rs10765939chr11:12298540:A:T--0.0465288793994850.00254739522247839LUSCMale-baised eQTL
rs1493962chr11:12299150:A:G--0.04653123829694120.00255446158183594LUSCMale-baised eQTL
rs12274358chr11:23580467:A:T-0.04620875688387960.00328400436137037LUSCMale-baised eQTL
rs113715113chr11:23616115:C:G-0.0455399265459460.00406002819564632LUSCMale-baised eQTL
rs28660253chr11:23614813:C:T-0.04486862194544590.0048617523626939LUSCMale-baised eQTL
rs7926252chr11:23638966:C:T-0.04420626733048940.00570978415186368LUSCMale-baised eQTL
rs11027412chr11:23642359:A:G-0.04420626733048940.00570978415186368LUSCMale-baised eQTL
rs12294583chr11:23617396:A:G-0.04357577383192210.006745014267755LUSCMale-baised eQTL
rs73431985chr11:23626823:G:A-0.04357577383192210.006745014267755LUSCMale-baised eQTL
rs11500118chr11:23634134:T:C-0.04357566482721280.006745014267755LUSCMale-baised eQTL
rs11027408chr11:23639822:C:G-0.04357566482721280.006745014267755LUSCMale-baised eQTL
rs16933952chr11:17313233:A:C-0.05866533848871780.00723368852182532LUSCMale-baised eQTL
rs73417234chr11:17319150:G:A-0.05866533848871780.00723368852182532LUSCMale-baised eQTL
rs114794906chr11:17326013:T:C-0.05866533848871780.00723368852182532LUSCMale-baised eQTL
rs113880886chr11:17336709:G:C-0.05866533848871780.00723368852182532LUSCMale-baised eQTL
rs75207092chr11:17330791:A:C-0.0586620134573590.00727282458209073LUSCMale-baised eQTL
rs11500117chr11:23624072:T:C-0.04296432564741240.0079038729357033LUSCMale-baised eQTL
rs1389550chr11:12291024:C:G--0.03990371845656750.0144992421206061LUSCMale-baised eQTL
rs72857952chr11:9109942:C:A-0.03932644741687510.0222731230025846LUSCMale-baised eQTL
rs60652265chr11:20900760:T:A-0.05213022934981080.0232315563725456LUSCMale-baised eQTL
rs16911616chr11:23617907:C:G-0.03794299661187430.0251481496227217LUSCMale-baised eQTL
rs111249740chr11:9173964:G:A-0.03793811616038960.0307131080750165LUSCMale-baised eQTL
rs10832532chr11:15937171:T:G-0.04699313997092270.0493732940499246LUSCMale-baised eQTL
rs12295063chr11:12927055:C:A-0.1082801023350280.000440890137573888LUADMale-baised eQTL
rs61878820chr11:12933980:G:A-0.09095955696374480.00374972679162584LUADMale-baised eQTL
rs72932938chr11:20632921:A:G-0.09211247802838030.00881097157801699LUADMale-baised eQTL
rs72927515chr11:20606474:G:A-0.08017674589453780.0251748979784877LUADMale-baised eQTL
rs11025657chr11:20620830:C:T-0.06634650828011690.0357650978782371LUADMale-baised eQTL
rs61891788chr11:10344768:T:C-0.1065288139359870.0393960749542218LUADMale-baised eQTL
rs4910742chr11:5285279:G:A--0.07789329609790840.0394021135085068LUADMale-baised eQTL
rs61878586chr11:10083283:A:G-0.1061299775889220.0412556417358805LUADMale-baised eQTL

check buttonOpposite sex-biased eQTL regulation.
SNP IDSNP InfoPosition to GeneMale EffectMale FDRFemale EffectFemale FDRSex-biased Gene in CancerCancer Type

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Sex-biased eQTM regulation of gene

check buttonSex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).
eQTMDescription
eQTM boxplot analysisGene ID: ENSG00000110680
CpG Site: cg22085702
Position to Gene: promoter
Male Effect: -0.138761309093111
Female Effect: -
eQTM boxplot analysisGene ID: ENSG00000110680
CpG Site: cg05061471
Position to Gene: promoter
Male Effect: -0.128523822115546
Female Effect: -
eQTM boxplot analysisGene ID: ENSG00000110680
CpG Site: cg13491234
Position to Gene: promoter
Male Effect: -
Female Effect: -0.2457194170713
eQTM boxplot analysisGene ID: ENSG00000110680
CpG Site: cg12904004
Position to Gene: promoter
Male Effect: -
Female Effect: -0.166478915447437
eQTM boxplot analysisGene ID: ENSG00000110680
CpG Site: cg07238401
Position to Gene: promoter
Male Effect: -
Female Effect: -0.164334487007217

check buttonMale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type
cg22085702chr11:14972676promoter-0.1387613090931113.36111394752532e-09-0.44863108361387451.9282236573619613e-12LUAD
cg05061471chr11:14973015promoter-0.1285238221155466.08175575454361e-08-0.419785686040081936.232928873894368e-11LUAD

check buttonFemale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type
cg13491234chr11:14972684promoter-0.24571941707134.39455880429924e-15-0.70131388679587543.31647764425001e-19LIHC
cg12904004chr11:14972652promoter-0.1664789154474379.94041908218903e-09-0.56922831671686069.589663119401239e-12LIHC
cg07238401chr11:14972851promoter-0.1643344870072172.82905228577302e-08-0.56935950974467269.46231138391571e-12LIHC

check buttonOpposite sex-biased eQTM regulation.
CpG SiteCpG PostionCpG IslandPosition to GeneMale EffectMale FDRFemale EffectFemale FDRMale CorMale P-valueFemale CorFemale P-valueSex-biased Coding GeneCancer Type

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Sex-biased sQTL regulation of gene

check buttonSex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTLDescription

check buttonMale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonFemale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonOpposite sex-biased sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESMale EffectMale FDRFemale EffectFemale FDRCancer Type

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Sex-biased sQTM regulation of gene

check buttonSex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTMDescription

check buttonMale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonFemale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonOpposite sex-biased sQTM regulation.
EX IDEX InfoSkipped ExonCPG SiteCPG PositionCPG IslandPosition to EX EventsMale EffectMale FDRFemale EffectFemale FDRMale CorrelationMale P-valueFemale CorrelationFemale P-valueORF_annoCancer Type

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Related disease information of CALCA

check buttonDiseases associated with this gene (DisGeNET).
Gene IDGene SymbolDisease IDDisease NameNumber of PMIDSource
ENSG00000110680CALCAC0003865Arthritis, Adjuvant-Induced1CTD_human
ENSG00000110680CALCAC0004352Autistic Disorder1CTD_human
ENSG00000110680CALCAC0007370Catalepsy3CTD_human
ENSG00000110680CALCAC0007852Cervical Migraine Syndrome2CTD_human
ENSG00000110680CALCAC0013080Down Syndrome1CTD_human
ENSG00000110680CALCAC0013604Edema1CTD_human
ENSG00000110680CALCAC0018984Hemicrania migraine2CTD_human
ENSG00000110680CALCAC0020429Hyperalgesia4CTD_human
ENSG00000110680CALCAC0020437Hypercalcemia2CTD_human
ENSG00000110680CALCAC0020538Hypertensive disease2CTD_human
ENSG00000110680CALCAC0020542Pulmonary Hypertension1CTD_human
ENSG00000110680CALCAC0020796Profound Mental Retardation1CTD_human
ENSG00000110680CALCAC0021368Inflammation1CTD_human
ENSG00000110680CALCAC0025363Mental Retardation, Psychosocial1CTD_human
ENSG00000110680CALCAC0026141Milk-Alkali Syndrome2CTD_human
ENSG00000110680CALCAC0029408Degenerative polyarthritis1CTD_human
ENSG00000110680CALCAC0033578Prostatic Neoplasms1CTD_human
ENSG00000110680CALCAC0034069Pulmonary Fibrosis1CTD_human
ENSG00000110680CALCAC0040997Trigeminal Neuralgia1CTD_human
ENSG00000110680CALCAC0085129Bronchial Hyperreactivity2CTD_human
ENSG00000110680CALCAC0086743Osteoarthrosis Deformans1CTD_human
ENSG00000110680CALCAC0149931Migraine Disorders2CTD_human
ENSG00000110680CALCAC0149940Sciatic Neuropathy1CTD_human
ENSG00000110680CALCAC0151603Anasarca1CTD_human
ENSG00000110680CALCAC0154748Lesion of Sciatic Nerve1CTD_human
ENSG00000110680CALCAC0233612Waxy flexibility3CTD_human
ENSG00000110680CALCAC0242013Sciatic Neuritis1CTD_human
ENSG00000110680CALCAC0270858Abdominal Migraine2CTD_human
ENSG00000110680CALCAC0338480Common Migraine2CTD_human
ENSG00000110680CALCAC0338489Status Migrainosus2CTD_human
ENSG00000110680CALCAC0344315Depressed mood1PSYGENET
ENSG00000110680CALCAC0376358Malignant neoplasm of prostate1CTD_human
ENSG00000110680CALCAC0393786Trigeminal Neuralgia, Idiopathic1CTD_human
ENSG00000110680CALCAC0393787Secondary Trigeminal Neuralgia1CTD_human
ENSG00000110680CALCAC0432416Down Syndrome, Partial Trisomy 211CTD_human
ENSG00000110680CALCAC0432417Trisomy 21, Meiotic Nondisjunction1CTD_human
ENSG00000110680CALCAC0458247Allodynia4CTD_human
ENSG00000110680CALCAC0521664Acute Confusional Migraine2CTD_human
ENSG00000110680CALCAC0600467Neurogenic Inflammation1CTD_human
ENSG00000110680CALCAC0700438Sick Headaches2CTD_human
ENSG00000110680CALCAC0751081Trisomy 21, Mitotic Nondisjunction1CTD_human
ENSG00000110680CALCAC0751211Hyperalgesia, Primary4CTD_human
ENSG00000110680CALCAC0751212Hyperalgesia, Secondary4CTD_human
ENSG00000110680CALCAC0751213Tactile Allodynia4CTD_human
ENSG00000110680CALCAC0751214Hyperalgesia, Thermal4CTD_human
ENSG00000110680CALCAC0751217Hyperkinesia, Generalized2CTD_human
ENSG00000110680CALCAC0751924Neuralgia-Neuritis, Sciatic Nerve1CTD_human
ENSG00000110680CALCAC0751925Sciatic Nerve Palsy1CTD_human
ENSG00000110680CALCAC0917816Mental deficiency1CTD_human
ENSG00000110680CALCAC0971858Arthritis, Collagen-Induced1CTD_human
ENSG00000110680CALCAC0993582Arthritis, Experimental1CTD_human
ENSG00000110680CALCAC2936719Mechanical Allodynia4CTD_human
ENSG00000110680CALCAC3714756Intellectual Disability1CTD_human
ENSG00000110680CALCAC3887506Hyperkinesia2CTD_human
ENSG00000110680CALCAC4721507Alveolitis, Fibrosing1CTD_human