|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000108515 |
Summary for ENO3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000108515 | Gene symbol | ENO3 |
| Gene name | enolase 3 | |
| HGNC | 3354 | |
| Entrez ID | 2027 | |
| Gene type | protein_coding | |
| Synonyms | ENO3| | |
| UniProtAcc | P13929 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000108515 | ENO3 | DB01709 | 2-phospho-D-glyceric acid | SmallMoleculeDrug |
| ENSG00000108515 | ENO3 | DB01819 | Phosphoenolpyruvate | SmallMoleculeDrug |
| ENSG00000108515 | ENO3 | DB02726 | 2-Phosphoglycolic Acid | SmallMoleculeDrug |
| ENSG00000108515 | ENO3 | DB03645 | Phosphonoacetohydroxamic Acid | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ENO3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ENO3 | 1.05e+03 | 1.04e+00 | 4.15e-01 | 2.50e+00 | 1.26e-02 | 2.57e-02 | THCA |
| ENO3 | 6.22e+02 | 1.20e+00 | 2.64e-01 | 4.57e+00 | 4.93e-06 | 1.56e-05 | KIRP |
| ENO3 | 2.88e+03 | -3.97e+00 | 5.43e-01 | -7.31e+00 | 2.64e-13 | 7.85e-12 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ENO3 | 1.62e+02 | 1.22e+00 | 3.43e-01 | 3.55e+00 | 3.87e-04 | 1.53e-03 | READ |
Top |
Sex-biased somatic mutation for ENO3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for ENO3 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for ENO3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for ENO3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for ENO3 |
| TFs related to ENO3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LAML | PLAGL2 | ENO3 | 4.48e+00 | 9.85e-01 | 3.43e+00 | 5.90e-03 | Male-biased |
| ENO3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ENO3 |
| RBPs related to ES in ENO3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ENO3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs62052312 | chr17:14024757:A:C | - | 0.176459451982502 | 2.72082315756807e-06 | HNSC | Female-baised eQTL |
| rs8071450 | chr17:14053350:T:G | - | 0.111367745319336 | 0.00989553836182538 | HNSC | Female-baised eQTL |
| rs112415631 | chr17:2168780:G:C | - | 0.133972496839737 | 0.0178213490160975 | HNSC | Female-baised eQTL |
| rs72815303 | chr17:2096647:A:G | - | 0.33041369286901 | 0.00401514901738299 | GBM | Female-baised eQTL |
| rs111277136 | chr17:2226610:C:A | - | 0.305205281246875 | 0.0117475152237109 | GBM | Female-baised eQTL |
| rs73974893 | chr17:10916521:C:T | - | 0.326795865533572 | 0.025619396876267 | GBM | Female-baised eQTL |
| rs62052312 | chr17:14024757:A:C | - | 0.169644070117728 | 0.00226234605264131 | SARC | Female-baised eQTL |
| rs62052296 | chr17:14010547:G:T | - | 0.160182338377644 | 0.00428099215898519 | SARC | Female-baised eQTL |
| rs62052297 | chr17:14012517:T:C | - | 0.160182338377644 | 0.00428099215898519 | SARC | Female-baised eQTL |
| rs62052298 | chr17:14012669:A:G | - | 0.160182338377644 | 0.00428099215898519 | SARC | Female-baised eQTL |
| rs75955506 | chr17:14044684:T:C | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs62054085 | chr17:14046370:A:G | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs77344347 | chr17:14049281:T:C | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs62054087 | chr17:14050619:C:T | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs62054089 | chr17:14056460:T:G | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs62054090 | chr17:14057155:G:A | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs62054142 | chr17:14064299:A:T | - | 0.163907372541061 | 0.00434161966538605 | SARC | Female-baised eQTL |
| rs113582482 | chr17:14069166:C:T | - | 0.16397569970651 | 0.00434797660914073 | SARC | Female-baised eQTL |
| rs7207354 | chr17:14012897:T:A | - | 0.159916407382189 | 0.00442561706560825 | SARC | Female-baised eQTL |
| rs62052302 | chr17:14014280:C:T | - | 0.159916407382189 | 0.00442561706560825 | SARC | Female-baised eQTL |
| rs10521251 | chr17:14040976:C:G | - | 0.159705343577228 | 0.00443570707056343 | SARC | Female-baised eQTL |
| rs62052305 | chr17:14016477:T:C | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs62052308 | chr17:14019036:C:A | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs199532345 | chr17:14025564:C:T | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs199786779 | chr17:14028652:C:T | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs199558455 | chr17:14029797:A:G | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs62054072 | chr17:14032342:A:T | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs113270018 | chr17:14036238:G:A | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs62054075 | chr17:14037850:T:C | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs62054076 | chr17:14037896:G:T | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs80300395 | chr17:14043736:A:G | - | 0.15964455098599 | 0.00450624862746094 | SARC | Female-baised eQTL |
| rs8076787 | chr17:14069638:C:T | - | 0.156608837895011 | 0.00626839904004938 | SARC | Female-baised eQTL |
| rs62054153 | chr17:14090606:G:A | - | 0.156608837895011 | 0.00626839904004938 | SARC | Female-baised eQTL |
| rs62054156 | chr17:14092872:A:G | - | 0.156361775718122 | 0.00650561270140074 | SARC | Female-baised eQTL |
| rs6502324 | chr17:14004969:T:C | - | 0.150023491012799 | 0.00898575451786477 | SARC | Female-baised eQTL |
| rs6502325 | chr17:14005372:C:T | - | 0.150023491012799 | 0.00898575451786477 | SARC | Female-baised eQTL |
| rs62054088 | chr17:14055896:G:T | - | 0.152052096931416 | 0.0105850208278273 | SARC | Female-baised eQTL |
| rs62054146 | chr17:14070968:G:A | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs79367432 | chr17:14075038:G:A | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs75797755 | chr17:14075570:A:G | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs2230351 | chr17:14076741:A:T | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs2072278 | chr17:14077333:T:G | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs62054151 | chr17:14081987:G:A | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs62054154 | chr17:14091539:A:G | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs8081179 | chr17:14091848:A:G | - | 0.146540248711617 | 0.0130466197397131 | SARC | Female-baised eQTL |
| rs62054149 | chr17:14080577:G:A | - | 0.146384493675798 | 0.0133446630618765 | SARC | Female-baised eQTL |
| rs62054155 | chr17:14092772:C:T | - | 0.146288026706451 | 0.01348600233204 | SARC | Female-baised eQTL |
| rs62052277 | chr17:13993076:T:C | - | 0.135606662714328 | 0.0226627397428962 | SARC | Female-baised eQTL |
| rs62052279 | chr17:13993687:C:G | - | 0.135435317428728 | 0.0229278157340448 | SARC | Female-baised eQTL |
| rs17607653 | chr17:13995904:G:A | - | 0.135435317428728 | 0.0229278157340448 | SARC | Female-baised eQTL |
| rs7406737 | chr17:959621:C:A | - | -0.188482362052812 | 0.000302240578972117 | KIRP | Female-baised eQTL |
| rs4025781 | chr17:959651:A:G | - | -0.188482362052812 | 0.000302240578972117 | KIRP | Female-baised eQTL |
| rs2457274 | chr17:960311:T:A | - | -0.155803626432149 | 0.00442429004024751 | KIRP | Female-baised eQTL |
| rs2457273 | chr17:960346:G:A | - | -0.155803626432149 | 0.00442429004024751 | KIRP | Female-baised eQTL |
| rs112951329 | chr17:13177159:G:A | - | 0.186789861302487 | 0.00527723028955365 | KIRP | Female-baised eQTL |
| rs7211772 | chr17:14461234:C:T | - | 0.19987952506815 | 0.00564713496051121 | KIRP | Female-baised eQTL |
| rs79661803 | chr17:13188793:A:G | - | 0.191492086764734 | 0.012413191688295 | KIRP | Female-baised eQTL |
| rs78685864 | chr17:13177740:A:G | - | 0.190958658747598 | 0.0132233034214589 | KIRP | Female-baised eQTL |
| rs80016613 | chr17:13188756:A:G | - | 0.173025070550381 | 0.0215291282808297 | KIRP | Female-baised eQTL |
| rs28533581 | chr17:6341645:C:T | - | 0.248076838733541 | 0.0226727820282698 | KIRP | Female-baised eQTL |
| rs9894935 | chr17:6341857:T:C | - | 0.248076838733541 | 0.0226727820282698 | KIRP | Female-baised eQTL |
| rs62062028 | chr17:6342915:G:A | - | 0.248076838733541 | 0.0226727820282698 | KIRP | Female-baised eQTL |
| rs74937614 | chr17:13198257:G:C | - | 0.150866707241963 | 0.0362306044819014 | KIRP | Female-baised eQTL |
| rs78856442 | chr17:13181837:C:T | - | 0.172839701863371 | 0.0363951506439008 | KIRP | Female-baised eQTL |
| rs79473656 | chr17:13185738:G:C | - | 0.172839701863371 | 0.0363951506439008 | KIRP | Female-baised eQTL |
| rs76029977 | chr17:13177791:T:A | - | 0.172289404312982 | 0.0385059580799027 | KIRP | Female-baised eQTL |
| rs7215798 | chr17:4104372:G:C | - | 0.104598372971306 | 0.0378903523119948 | LIHC | Female-baised eQTL |
| rs971718 | chr17:13221732:T:C | - | 0.104365999570414 | 0.000102455357683147 | KIRC | Female-baised eQTL |
| rs35679931 | chr17:368845:C:T | - | 0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs12941892 | chr17:369156:G:C | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs12946805 | chr17:369276:T:C | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs74590527 | chr17:369345:A:C | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs12949557 | chr17:369376:G:C | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs11650058 | chr17:369384:A:G | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs12942299 | chr17:369418:C:T | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs9892274 | chr17:369768:A:G | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs11871312 | chr17:370594:G:C | - | -0.0855551367982278 | 0.000136798842570775 | KIRC | Female-baised eQTL |
| rs12150632 | chr17:12676693:A:C | - | 0.0708569710091658 | 0.00481703456252151 | KIRC | Female-baised eQTL |
| rs3912923 | chr17:3403115:G:T | - | 0.0821349501609344 | 0.0080069459469255 | KIRC | Female-baised eQTL |
| rs4968066 | chr17:951013:C:A | - | 0.0882445075155305 | 0.0150630455784555 | KIRC | Female-baised eQTL |
| rs117582359 | chr17:951403:C:T | - | 0.0882445075155305 | 0.0150630455784555 | KIRC | Female-baised eQTL |
| rs2287498 | chr17:7689242:C:T | - | 0.0618294180187414 | 0.0175945181984673 | KIRC | Female-baised eQTL |
| rs200894178 | chr17:3351475:G:A | - | 0.0800887417594283 | 0.0291922755284331 | KIRC | Female-baised eQTL |
| rs78032260 | chr17:949791:G:A | - | 0.0791748120630081 | 0.0331110758145012 | KIRC | Female-baised eQTL |
| rs7207700 | chr17:12913054:C:G | - | 0.0718036411225649 | 0.0339037915422184 | KIRC | Female-baised eQTL |
| rs74252396 | chr17:3409942:A:T | - | 0.0832556356386889 | 0.0347311882523516 | KIRC | Female-baised eQTL |
| rs16953007 | chr17:3410023:C:T | - | 0.0832556356386889 | 0.0347311882523516 | KIRC | Female-baised eQTL |
| rs78365241 | chr17:3410124:G:T | - | 0.0832556356386889 | 0.0347311882523516 | KIRC | Female-baised eQTL |
| rs3852802 | chr17:3398661:C:T | - | 0.0825526857849313 | 0.038474720298715 | KIRC | Female-baised eQTL |
| rs3912924 | chr17:3402147:T:G | - | 0.0825526857849313 | 0.038474720298715 | KIRC | Female-baised eQTL |
| rs112647169 | chr17:3396685:G:A | - | 0.0825638290127982 | 0.0385652624501329 | KIRC | Female-baised eQTL |
| rs199861446 | chr17:3370794:C:G | - | 0.0768363928236872 | 0.0405293237098293 | KIRC | Female-baised eQTL |
| rs73296283 | chr17:2365098:G:T | - | 0.0871853518119579 | 0.0485902010674749 | KIRC | Female-baised eQTL |
| rs61644407 | chr17:601889:A:C | - | 0.156106483108261 | 0.000459075981086564 | BLCA | Female-baised eQTL |
| rs7207203 | chr17:694070:T:C | - | 0.156259145114827 | 0.000464018899006122 | BLCA | Female-baised eQTL |
| rs79951859 | chr17:711165:C:T | - | 0.156259145114827 | 0.000464018899006122 | BLCA | Female-baised eQTL |
| rs12150419 | chr17:671903:G:A | - | 0.155980641454801 | 0.000477922006666958 | BLCA | Female-baised eQTL |
| rs56214309 | chr17:672305:G:A | - | 0.155980641454801 | 0.000477922006666958 | BLCA | Female-baised eQTL |
| rs78950287 | chr17:684496:C:T | - | 0.155980641454801 | 0.000477922006666958 | BLCA | Female-baised eQTL |
| rs2543767 | chr17:726435:T:C | - | 0.155980641454801 | 0.000477922006666958 | BLCA | Female-baised eQTL |
| rs77513256 | chr17:726945:G:C | - | 0.155980641454801 | 0.000477922006666958 | BLCA | Female-baised eQTL |
| rs182189541 | chr17:643645:G:C | - | 0.155297653066258 | 0.000528560571196789 | BLCA | Female-baised eQTL |
| rs77937721 | chr17:665203:G:A | - | 0.155398259315308 | 0.000537258104239185 | BLCA | Female-baised eQTL |
| rs79671786 | chr17:667735:C:G | - | 0.155398259315308 | 0.000537258104239185 | BLCA | Female-baised eQTL |
| rs12600493 | chr17:588484:A:G | - | 0.157696883727934 | 0.000725195028828957 | BLCA | Female-baised eQTL |
| rs201604974 | chr17:591840:T:C | - | 0.157696883727934 | 0.000725195028828957 | BLCA | Female-baised eQTL |
| rs12603291 | chr17:598123:C:T | - | 0.157696883727934 | 0.000725195028828957 | BLCA | Female-baised eQTL |
| rs150674644 | chr17:610005:G:A | - | 0.14498491028307 | 0.00163376280805511 | BLCA | Female-baised eQTL |
| rs60861562 | chr17:600648:A:C | - | 0.14636683054612 | 0.00222505715999535 | BLCA | Female-baised eQTL |
| rs7218543 | chr17:614880:G:A | - | -0.145995478848433 | 0.00247023114214402 | BLCA | Female-baised eQTL |
| rs76207825 | chr17:14676636:A:G | - | 0.167792237520278 | 0.00296948310821641 | BLCA | Female-baised eQTL |
| rs12603935 | chr17:8072134:G:A | - | 0.164822139505476 | 0.00425755350743096 | BLCA | Female-baised eQTL |
| rs78835850 | chr17:8073599:A:T | - | 0.164822139505476 | 0.00425755350743096 | BLCA | Female-baised eQTL |
| rs72825340 | chr17:12397671:A:G | - | 0.154495613611425 | 0.00573425114352211 | BLCA | Female-baised eQTL |
| rs117974450 | chr17:12405714:G:A | - | 0.153091992768858 | 0.00676661729200626 | BLCA | Female-baised eQTL |
| rs2014799 | chr17:561057:T:C | - | 0.121495034082282 | 0.0114619883672264 | BLCA | Female-baised eQTL |
| rs117565056 | chr17:582148:C:T | - | 0.123351483909482 | 0.0170738159820859 | BLCA | Female-baised eQTL |
| rs118144008 | chr17:582151:C:T | - | 0.123351483909482 | 0.0170738159820859 | BLCA | Female-baised eQTL |
| rs201758644 | chr17:582163:T:C | - | 0.123351483909482 | 0.0170738159820859 | BLCA | Female-baised eQTL |
| rs200102839 | chr17:582167:C:T | - | 0.123351483909482 | 0.0170738159820859 | BLCA | Female-baised eQTL |
| rs72815303 | chr17:2096647:A:G | - | 0.126929764115472 | 0.0217547199264829 | BLCA | Female-baised eQTL |
| rs11652361 | chr17:2158901:A:T | - | 0.132810223173257 | 0.0311781131497901 | BLCA | Female-baised eQTL |
| rs9906839 | chr17:12712796:T:A | - | 0.0914595723950614 | 0.0439867621465918 | BLCA | Female-baised eQTL |
| rs72826578 | chr17:5755343:T:C | - | 0.126798691908845 | 0.0449347522204621 | BLCA | Female-baised eQTL |
| rs59554068 | chr17:5456518:A:G | - | 0.0353226258069175 | 0.0052651587574134 | LUAD | Female-baised eQTL |
| rs11867311 | chr17:5455351:C:T | - | 0.0353597038186361 | 0.00535393497848567 | LUAD | Female-baised eQTL |
| rs16954813 | chr17:5509502:G:A | - | 0.0379523465437477 | 0.00841943861297469 | LUAD | Female-baised eQTL |
| rs61099937 | chr17:5509592:A:C | - | 0.0370259654193697 | 0.0104320347336844 | LUAD | Female-baised eQTL |
| rs4239264 | chr17:6407544:A:C | - | 0.0388659120827765 | 0.0108642422000031 | LUAD | Female-baised eQTL |
| rs8070409 | chr17:6406202:T:A | - | 0.0360970792126097 | 0.0127546384641457 | LUAD | Female-baised eQTL |
| rs9902174 | chr17:5493493:A:G | - | 0.0324869880274224 | 0.0130752824889429 | LUAD | Female-baised eQTL |
| rs57010704 | chr17:5509704:T:C | - | 0.0364432098424383 | 0.0131264830769249 | LUAD | Female-baised eQTL |
| rs12602566 | chr17:5510110:C:T | - | 0.0362064747521367 | 0.0143003896125294 | LUAD | Female-baised eQTL |
| rs6502861 | chr17:5460653:C:T | - | 0.0371525169520539 | 0.0156221069447145 | LUAD | Female-baised eQTL |
| rs1805434 | chr17:5486742:A:T | - | 0.0321082272505189 | 0.0166744924787143 | LUAD | Female-baised eQTL |
| rs1805462 | chr17:5486808:A:G | - | 0.0319469741858723 | 0.0182342448739577 | LUAD | Female-baised eQTL |
| rs8065791 | chr17:6405872:A:G | - | 0.0348127285321327 | 0.0184419248246862 | LUAD | Female-baised eQTL |
| rs9903431 | chr17:6407411:C:T | - | 0.0364873862321083 | 0.0185945249372956 | LUAD | Female-baised eQTL |
| rs73339265 | chr17:5461353:T:C | - | 0.0318203255424404 | 0.0190894356424957 | LUAD | Female-baised eQTL |
| rs12602960 | chr17:5511006:G:T | - | 0.0338554184338598 | 0.0192899085502965 | LUAD | Female-baised eQTL |
| rs9912028 | chr17:5460303:T:C | - | 0.0317656383594947 | 0.0195403374168308 | LUAD | Female-baised eQTL |
| rs8069978 | chr17:5477722:C:A | - | 0.0315390358407047 | 0.0208088098148645 | LUAD | Female-baised eQTL |
| rs7223522 | chr17:5487384:T:C | - | 0.03157691246535 | 0.0208676453294388 | LUAD | Female-baised eQTL |
| rs7218803 | chr17:5487425:C:G | - | 0.03157691246535 | 0.0208676453294388 | LUAD | Female-baised eQTL |
| rs6502864 | chr17:5487714:G:T | - | 0.03157691246535 | 0.0208676453294388 | LUAD | Female-baised eQTL |
| rs111905603 | chr17:6398036:A:G | - | 0.0631818047593416 | 0.021062998268663 | LUAD | Female-baised eQTL |
| rs3865351 | chr17:5478711:C:T | - | 0.0308933679748092 | 0.0256204435038024 | LUAD | Female-baised eQTL |
| rs7224033 | chr17:5479477:A:G | - | 0.0308933679748092 | 0.0256204435038024 | LUAD | Female-baised eQTL |
| rs8070008 | chr17:5463330:C:G | - | 0.0303438286873012 | 0.0275489906464013 | LUAD | Female-baised eQTL |
| rs57724035 | chr17:5498386:C:T | - | 0.0345932379970989 | 0.0342534920320367 | LUAD | Female-baised eQTL |
| rs8073764 | chr17:5507994:C:T | - | 0.033600913834695 | 0.0369306371813459 | LUAD | Female-baised eQTL |
| rs8072806 | chr17:5508044:G:C | - | 0.033600913834695 | 0.0369306371813459 | LUAD | Female-baised eQTL |
| rs57672697 | chr17:5508284:C:T | - | 0.0335863377363056 | 0.0370757823804103 | LUAD | Female-baised eQTL |
| rs11654206 | chr17:5494416:T:C | - | 0.0307454334360162 | 0.0372565120086946 | LUAD | Female-baised eQTL |
| rs57512487 | chr17:5508230:C:A | - | 0.0334118737292235 | 0.0386432209037249 | LUAD | Female-baised eQTL |
| rs9914251 | chr17:5491562:A:G | - | 0.0331682645532456 | 0.0387575361916945 | LUAD | Female-baised eQTL |
| rs55881499 | chr17:5497430:C:T | - | 0.0337586603608621 | 0.0392027882431286 | LUAD | Female-baised eQTL |
| rs9889906 | chr17:9566045:T:G | - | -0.0372025341153083 | 0.0408579591740752 | LUAD | Female-baised eQTL |
| rs8068672 | chr17:5507782:G:A | - | 0.0331304689753495 | 0.0415506198913163 | LUAD | Female-baised eQTL |
| rs8079523 | chr17:9572276:C:T | - | -0.0368184329489361 | 0.0458082057474223 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs201391689 | chr17:3327085:T:A | - | 0.0497567199038854 | 0.039309553058701 | HNSC | Male-baised eQTL |
| rs8064800 | chr17:3017957:A:G | - | -0.060188852900395 | 0.000523457969508522 | LUSC | Male-baised eQTL |
| rs7216894 | chr17:3016506:A:G | - | -0.0578319895237721 | 0.000950343931013448 | LUSC | Male-baised eQTL |
| rs11651750 | chr17:3019190:C:T | - | -0.0566424560148629 | 0.000985379424198433 | LUSC | Male-baised eQTL |
| rs4790414 | chr17:3020175:C:T | - | -0.0524283881348987 | 0.00368521192894654 | LUSC | Male-baised eQTL |
| rs4239034 | chr17:3019939:G:C | - | -0.0493801258544508 | 0.0065791254958749 | LUSC | Male-baised eQTL |
| rs4239035 | chr17:3019975:C:T | - | -0.0493801258544508 | 0.0065791254958749 | LUSC | Male-baised eQTL |
| rs227790 | chr17:3419530:A:G | - | 0.0257545371972655 | 0.0230329628253936 | LUSC | Male-baised eQTL |
| rs149888324 | chr17:3404938:G:C | - | 0.0640639562863326 | 0.0286458697080949 | LGG | Male-baised eQTL |
| rs11868628 | chr17:12958992:T:C | - | 0.0564971228616675 | 0.0345435398345447 | LGG | Male-baised eQTL |
| rs11078104 | chr17:12966947:C:T | - | 0.0493327555300137 | 0.0379783560657197 | LGG | Male-baised eQTL |
| rs2215242 | chr17:11409439:A:G | - | 0.0531689885119354 | 0.000769948112890729 | KIRC | Male-baised eQTL |
| rs72807145 | chr17:11408003:C:G | - | 0.0562082925636564 | 0.000912303138552303 | KIRC | Male-baised eQTL |
| rs16943591 | chr17:10643757:A:C | - | -0.0346135077893432 | 0.0133295186330294 | KIRC | Male-baised eQTL |
| rs2239935 | chr17:10644867:T:C | - | -0.0346135077893432 | 0.0133295186330294 | KIRC | Male-baised eQTL |
| rs11654019 | chr17:10645076:T:C | - | -0.0346135077893432 | 0.0133295186330294 | KIRC | Male-baised eQTL |
| rs2285468 | chr17:10642813:T:G | - | -0.0345050245388805 | 0.0141300051718276 | KIRC | Male-baised eQTL |
| rs2040569 | chr17:10643902:G:T | - | -0.0346229397076029 | 0.0146700674289431 | KIRC | Male-baised eQTL |
| rs3760432 | chr17:10647669:T:C | - | -0.0353210614337295 | 0.0159643634785898 | KIRC | Male-baised eQTL |
| rs3785938 | chr17:10650620:A:G | - | -0.0353210614337295 | 0.0159643634785898 | KIRC | Male-baised eQTL |
| rs6503315 | chr17:10627933:T:C | - | -0.0321681736058066 | 0.0221825750945792 | KIRC | Male-baised eQTL |
| rs2239930 | chr17:10655416:G:A | - | -0.0327651759499575 | 0.0230462614690102 | KIRC | Male-baised eQTL |
| rs9893964 | chr17:5716063:G:A | - | 0.0542402052077509 | 0.0284219760075531 | KIRC | Male-baised eQTL |
| rs3815011 | chr17:10653588:C:G | - | -0.031549819626868 | 0.0307727083628786 | KIRC | Male-baised eQTL |
| rs3815010 | chr17:10653648:T:C | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs3815005 | chr17:10654278:T:A | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs12950539 | chr17:10656022:A:G | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs2285462 | chr17:10656255:A:G | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs2285461 | chr17:10656344:A:G | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs7220249 | chr17:10656467:A:G | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs7222872 | chr17:10656767:G:A | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs6503317 | chr17:10657024:G:A | - | -0.031478443474386 | 0.0311989816668846 | KIRC | Male-baised eQTL |
| rs34749455 | chr17:11613320:T:A | - | 0.0598841035864424 | 0.031409223634383 | KIRC | Male-baised eQTL |
| rs205062 | chr17:11393128:G:C | - | -0.0383403338315277 | 0.0347015329005822 | KIRC | Male-baised eQTL |
| rs2429375 | chr17:11393955:G:A | - | -0.0382026235349509 | 0.0370806237307463 | KIRC | Male-baised eQTL |
| rs2239932 | chr17:10646235:C:A | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs2239931 | chr17:10646715:G:A | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs4792009 | chr17:10646786:A:G | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs1989811 | chr17:10649305:C:T | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs1989810 | chr17:10649729:A:G | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs7406933 | chr17:10649998:A:G | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs7209483 | chr17:10650877:G:T | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs7215508 | chr17:10650956:T:A | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs7210843 | chr17:10651041:C:T | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs2285465 | chr17:10652037:A:G | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs34842079 | chr17:10655824:C:G | - | -0.0307221165056746 | 0.0376691200758342 | KIRC | Male-baised eQTL |
| rs2097657 | chr17:10649171:G:A | - | -0.0303098777308537 | 0.0398780246492406 | KIRC | Male-baised eQTL |
| rs11658704 | chr17:2520742:C:T | - | -0.0946126057316731 | 0.00555437548571796 | LUAD | Male-baised eQTL |
| rs8074405 | chr17:2497069:A:G | - | -0.0840813487416394 | 0.0168698514353148 | LUAD | Male-baised eQTL |
| rs55716550 | chr17:6799488:G:A | - | 0.0773803788953666 | 0.040580007913533 | COAD | Male-baised eQTL |
| rs141107147 | chr17:6792072:C:T | - | 0.0776824492983729 | 0.0416770833589695 | COAD | Male-baised eQTL |
| rs4985682 | chr17:5754995:T:C | - | 0.0443250959260208 | 0.0473518251305966 | COAD | Male-baised eQTL |
| rs60825244 | chr17:6788785:C:T | - | 0.0688847163023793 | 0.0481499327880341 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000108515 |
| CpG Site: cg27207493 | |
| Position to Gene: gene,exon,enhancer,CDS | |
| Male Effect: -0.479216610636863 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108515 |
| CpG Site: cg27207493 | |
| Position to Gene: gene,exon,enhancer,CDS | |
| Male Effect: -0.260283059739491 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108515 |
| CpG Site: cg27207493 | |
| Position to Gene: gene,exon,enhancer,CDS | |
| Male Effect: -0.367139615894446 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg27207493 | chr17:4951854 | gene,exon,enhancer,CDS | -0.479216610636863 | 3.91381079531397e-67 | -0.8936048148362482 | 3.709417351027589e-71 | KIRP |
| cg27207493 | chr17:4951854 | gene,exon,enhancer,CDS | -0.260283059739491 | 7.39842561068879e-14 | -0.5264073032699617 | 2.696650694254175e-17 | LUAD |
| cg27207493 | chr17:4951854 | gene,exon,enhancer,CDS | -0.367139615894446 | 3.74182765313364e-72 | -0.8360863787515109 | 1.3525701776286753e-77 | SKCM |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of ENO3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000108515 | ENO3 | C0023895 | Liver diseases | 1 | CTD_human |
| ENSG00000108515 | ENO3 | C0086565 | Liver Dysfunction | 1 | CTD_human |
| ENSG00000108515 | ENO3 | C2752027 | Glycogen Storage Disease XIII | 1 | CTD_human |
