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Gene: ENSG00000108511 |
Summary for HOXB6 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000108511 | Gene symbol | HOXB6 |
| Gene name | homeobox B6 | |
| HGNC | 5117 | |
| Entrez ID | 3216 | |
| Gene type | protein_coding | |
| Synonyms | HOXB6| | |
| UniProtAcc | P17509 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for HOXB6 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| HOXB6 | 7.26e+02 | 1.03e+00 | 1.88e-01 | 5.47e+00 | 4.47e-08 | 9.58e-06 | BLCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| HOXB6 | 9.42e+02 | -1.40e+00 | 2.88e-01 | -4.86e+00 | 1.17e-06 | 4.12e-06 | KIRP |
| HOXB6 | 1.36e+03 | 1.24e+00 | 2.88e-01 | 4.30e+00 | 1.71e-05 | 5.34e-05 | COAD |
| HOXB6 | 3.35e+02 | 3.43e+00 | 7.95e-01 | 4.31e+00 | 1.61e-05 | 8.57e-05 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| HOXB6 | 4.66e+02 | 1.02e+00 | 2.88e-01 | 3.55e+00 | 3.82e-04 | 7.86e-04 | LUAD |
| HOXB6 | 4.94e+02 | 1.56e+00 | 1.87e-01 | 8.38e+00 | 5.09e-17 | 1.52e-16 | BRCA |
| HOXB6 | 1.29e+03 | 2.16e+00 | 4.83e-01 | 4.47e+00 | 7.91e-06 | 5.30e-05 | READ |
Top |
Sex-biased somatic mutation for HOXB6 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for HOXB6 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg15435170 | chr17:48603773 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 4.12e-01 | 2.70e-01 | 2.09e+00 | 3.64e-02 | 4.42e-02 | 1.41e-01 |
| BRCA | cg00072689 | chr17:48603749 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 3.75e-01 | 2.72e-01 | 1.97e+00 | 4.85e-02 | 4.94e-02 | 1.03e-01 |
| BRCA | cg01986016 | chr17:48603792 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 3.53e-01 | 2.50e-01 | 2.20e+00 | 2.78e-02 | 3.97e-02 | 1.03e-01 |
| BRCA | cg16848873 | chr17:48604946 | CGI:chr17:48607882-48608087 | UTR,promoter,exon,gene body | 4.39e-01 | 2.74e-01 | 2.25e+00 | 2.48e-02 | 3.79e-02 | 1.65e-01 |
| LIHC | cg04435975 | chr17:48605685 | CGI:chr17:48607882-48608087 | promoter | 3.40e-01 | 2.39e-01 | 2.28e+00 | 2.27e-02 | 3.02e-02 | 1.01e-01 |
| MESO | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 2.79e-01 | 4.45e-01 | -2.07e+00 | 3.89e-02 | 4.73e-02 | -1.65e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg10906729 | chr17:48605028 | CGI:chr17:48607882-48608087 | promoter | 1.40e-01 | 3.48e-02 | 6.41e+00 | 1.50e-10 | 3.37e-09 | 1.05e-01 |
| HNSC | cg17179862 | chr17:48604000 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 3.51e-01 | 2.10e-01 | 2.70e+00 | 6.92e-03 | 9.37e-03 | 1.41e-01 |
| HNSC | cg03803541 | chr17:48604039 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 3.39e-01 | 1.92e-01 | 3.23e+00 | 1.25e-03 | 2.20e-03 | 1.47e-01 |
| HNSC | cg10906729 | chr17:48605028 | CGI:chr17:48607882-48608087 | promoter | 5.33e-01 | 3.47e-01 | 2.35e+00 | 1.90e-02 | 2.20e-02 | 1.85e-01 |
| HNSC | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 6.54e-01 | 5.04e-01 | 2.57e+00 | 1.00e-02 | 1.29e-02 | 1.50e-01 |
| LUSC | cg19828220 | chr17:48605051 | CGI:chr17:48607882-48608087 | promoter | 4.89e-01 | 3.74e-01 | 2.25e+00 | 2.47e-02 | 2.82e-02 | 1.15e-01 |
| LUSC | cg10906729 | chr17:48605028 | CGI:chr17:48607882-48608087 | promoter | 5.14e-01 | 2.87e-01 | 2.02e+00 | 4.38e-02 | 4.48e-02 | 2.26e-01 |
| LUSC | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 6.40e-01 | 4.65e-01 | 2.11e+00 | 3.53e-02 | 3.76e-02 | 1.75e-01 |
| LUSC | cg02574073 | chr17:48605036 | CGI:chr17:48607882-48608087 | promoter | 6.41e-01 | 4.57e-01 | 2.13e+00 | 3.29e-02 | 3.55e-02 | 1.83e-01 |
| LUSC | cg04435975 | chr17:48605685 | CGI:chr17:48607882-48608087 | promoter | 6.85e-01 | 4.44e-01 | 3.15e+00 | 1.63e-03 | 3.62e-03 | 2.41e-01 |
| LUSC | cg20591728 | chr17:48606244 | CGI:chr17:48607882-48608087 | promoter | 9.52e-01 | 7.30e-01 | 4.29e+00 | 1.78e-05 | 5.26e-04 | 2.22e-01 |
| LUSC | cg18878432 | chr17:48606047 | CGI:chr17:48607882-48608087 | promoter | 8.75e-01 | 6.16e-01 | 4.18e+00 | 2.94e-05 | 5.26e-04 | 2.59e-01 |
| LUSC | cg07318128 | chr17:48606444 | CGI:chr17:48607882-48608087 | promoter | 8.82e-01 | 6.11e-01 | 4.38e+00 | 1.21e-05 | 5.26e-04 | 2.71e-01 |
| COAD | cg19828220 | chr17:48605051 | CGI:chr17:48607882-48608087 | promoter | 2.08e-01 | 3.16e-01 | -4.03e+00 | 5.67e-05 | 2.23e-04 | -1.08e-01 |
| COAD | cg15435170 | chr17:48603773 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 2.30e-01 | 3.40e-01 | -4.03e+00 | 5.67e-05 | 2.23e-04 | -1.10e-01 |
| COAD | cg17179862 | chr17:48604000 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 1.51e-01 | 2.56e-01 | -3.54e+00 | 4.05e-04 | 1.08e-03 | -1.06e-01 |
| COAD | cg03803541 | chr17:48604039 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 1.67e-01 | 2.68e-01 | -3.46e+00 | 5.43e-04 | 1.37e-03 | -1.01e-01 |
| COAD | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 1.49e-01 | 3.13e-01 | -3.70e+00 | 2.15e-04 | 6.48e-04 | -1.64e-01 |
| COAD | cg02574073 | chr17:48605036 | CGI:chr17:48607882-48608087 | promoter | 1.50e-01 | 2.80e-01 | -3.94e+00 | 8.29e-05 | 3.02e-04 | -1.29e-01 |
| COAD | cg20591728 | chr17:48606244 | CGI:chr17:48607882-48608087 | promoter | 6.78e-01 | 8.97e-01 | -1.98e+00 | 4.79e-02 | 4.84e-02 | -2.19e-01 |
| COAD | cg01986016 | chr17:48603792 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 2.21e-01 | 3.23e-01 | -3.99e+00 | 6.60e-05 | 2.52e-04 | -1.02e-01 |
| COAD | cg20471691 | chr17:48603954 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 2.59e-01 | 3.89e-01 | -3.94e+00 | 8.09e-05 | 2.96e-04 | -1.30e-01 |
| COAD | cg16848873 | chr17:48604946 | CGI:chr17:48607882-48608087 | UTR,promoter,exon,gene body | 1.69e-01 | 2.91e-01 | -3.91e+00 | 9.17e-05 | 3.28e-04 | -1.22e-01 |
| COAD | cg07318128 | chr17:48606444 | CGI:chr17:48607882-48608087 | promoter | 7.17e-01 | 8.77e-01 | -2.50e+00 | 1.25e-02 | 1.71e-02 | -1.60e-01 |
| BLCA | cg07318128 | chr17:48606444 | CGI:chr17:48607882-48608087 | promoter | 8.06e-01 | 6.82e-01 | 3.32e+00 | 8.97e-04 | 2.08e-03 | 1.25e-01 |
| LIHC | cg19828220 | chr17:48605051 | CGI:chr17:48607882-48608087 | promoter | 2.32e-01 | 3.41e-01 | -4.24e+00 | 2.22e-05 | 5.49e-05 | -1.09e-01 |
| LIHC | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 2.45e-01 | 4.03e-01 | -3.11e+00 | 1.88e-03 | 2.77e-03 | -1.58e-01 |
| LIHC | cg02574073 | chr17:48605036 | CGI:chr17:48607882-48608087 | promoter | 2.74e-01 | 3.86e-01 | -2.16e+00 | 3.08e-02 | 3.27e-02 | -1.12e-01 |
| LIHC | cg20471691 | chr17:48603954 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 3.05e-01 | 4.16e-01 | -4.03e+00 | 5.48e-05 | 1.21e-04 | -1.11e-01 |
| LIHC | cg16848873 | chr17:48604946 | CGI:chr17:48607882-48608087 | UTR,promoter,exon,gene body | 2.29e-01 | 3.59e-01 | -5.20e+00 | 2.00e-07 | 9.43e-07 | -1.30e-01 |
| LIHC | cg05888755 | chr17:48604957 | CGI:chr17:48607882-48608087 | UTR,promoter,exon,gene body | 2.30e-01 | 3.60e-01 | -4.60e+00 | 4.25e-06 | 1.30e-05 | -1.29e-01 |
| KIRP | cg04435975 | chr17:48605685 | CGI:chr17:48607882-48608087 | promoter | 5.06e-01 | 2.96e-01 | 2.38e+00 | 1.74e-02 | 2.05e-02 | 2.10e-01 |
| CHOL | cg03803541 | chr17:48604039 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 4.21e-01 | 1.91e-01 | 1.99e+00 | 4.65e-02 | 4.65e-02 | 2.30e-01 |
| CHOL | cg04435975 | chr17:48605685 | CGI:chr17:48607882-48608087 | promoter | 4.89e-01 | 2.35e-01 | 2.29e+00 | 2.23e-02 | 3.24e-02 | 2.53e-01 |
| CHOL | cg20591728 | chr17:48606244 | CGI:chr17:48607882-48608087 | promoter | 9.28e-01 | 6.58e-01 | 3.46e+00 | 5.30e-04 | 8.63e-03 | 2.70e-01 |
| CHOL | cg18878432 | chr17:48606047 | CGI:chr17:48607882-48608087 | promoter | 7.58e-01 | 5.39e-01 | -2.43e+00 | 1.50e-02 | 2.65e-02 | 2.19e-01 |
| CHOL | cg07318128 | chr17:48606444 | CGI:chr17:48607882-48608087 | promoter | 8.50e-01 | 5.76e-01 | 3.54e+00 | 4.02e-04 | 8.32e-03 | 2.75e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg19828220 | chr17:48605051 | CGI:chr17:48607882-48608087 | promoter | 4.51e-01 | 2.80e-01 | 8.73e+00 | 2.52e-18 | 1.19e-17 | 1.71e-01 |
| BRCA | cg17179862 | chr17:48604000 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 2.65e-01 | 1.29e-01 | 5.86e+00 | 4.75e-09 | 1.09e-08 | 1.36e-01 |
| BRCA | cg03803541 | chr17:48604039 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 2.45e-01 | 1.11e-01 | 6.90e+00 | 5.34e-12 | 1.55e-11 | 1.33e-01 |
| BRCA | cg10906729 | chr17:48605028 | CGI:chr17:48607882-48608087 | promoter | 5.04e-01 | 1.70e-01 | 7.38e+00 | 1.54e-13 | 5.04e-13 | 3.34e-01 |
| BRCA | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 6.21e-01 | 2.69e-01 | 5.56e+00 | 2.71e-08 | 5.83e-08 | 3.52e-01 |
| BRCA | cg02574073 | chr17:48605036 | CGI:chr17:48607882-48608087 | promoter | 6.35e-01 | 3.04e-01 | 4.79e+00 | 1.63e-06 | 2.96e-06 | 3.31e-01 |
| BRCA | cg04435975 | chr17:48605685 | CGI:chr17:48607882-48608087 | promoter | 4.70e-01 | 2.98e-01 | 5.95e+00 | 2.63e-09 | 6.17e-09 | 1.72e-01 |
| BRCA | cg16848873 | chr17:48604946 | CGI:chr17:48607882-48608087 | UTR,promoter,exon,gene body | 4.39e-01 | 2.80e-01 | 6.45e+00 | 1.13e-10 | 2.96e-10 | 1.59e-01 |
| BRCA | cg05888755 | chr17:48604957 | CGI:chr17:48607882-48608087 | UTR,promoter,exon,gene body | 4.20e-01 | 2.35e-01 | 6.12e+00 | 9.09e-10 | 2.22e-09 | 1.85e-01 |
| LUAD | cg19828220 | chr17:48605051 | CGI:chr17:48607882-48608087 | promoter | 4.82e-01 | 3.62e-01 | 2.43e+00 | 1.52e-02 | 2.12e-02 | 1.20e-01 |
| LUAD | cg03803541 | chr17:48604039 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 4.24e-01 | 3.13e-01 | 1.97e+00 | 4.83e-02 | 4.87e-02 | 1.11e-01 |
| LUAD | cg10906729 | chr17:48605028 | CGI:chr17:48607882-48608087 | promoter | 5.15e-01 | 3.20e-01 | 1.97e+00 | 4.83e-02 | 4.87e-02 | 1.95e-01 |
| LUAD | cg18684142 | chr17:48605032 | CGI:chr17:48607882-48608087 | promoter | 6.40e-01 | 4.42e-01 | 2.24e+00 | 2.48e-02 | 3.02e-02 | 1.98e-01 |
| LUAD | cg02574073 | chr17:48605036 | CGI:chr17:48607882-48608087 | promoter | 6.44e-01 | 4.63e-01 | 2.10e+00 | 3.56e-02 | 3.91e-02 | 1.81e-01 |
| LUAD | cg04435975 | chr17:48605685 | CGI:chr17:48607882-48608087 | promoter | 5.79e-01 | 4.22e-01 | 2.50e+00 | 1.24e-02 | 1.84e-02 | 1.57e-01 |
| LIHC | cg20591728 | chr17:48606244 | CGI:chr17:48607882-48608087 | promoter | 7.07e-01 | 5.49e-01 | 2.96e+00 | 3.07e-03 | 5.45e-03 | 1.58e-01 |
| LIHC | cg18878432 | chr17:48606047 | CGI:chr17:48607882-48608087 | promoter | 5.14e-01 | 3.78e-01 | 2.25e+00 | 2.47e-02 | 2.85e-02 | 1.36e-01 |
| LIHC | cg07318128 | chr17:48606444 | CGI:chr17:48607882-48608087 | promoter | 6.72e-01 | 5.38e-01 | 2.95e+00 | 3.19e-03 | 5.63e-03 | 1.34e-01 |
| KIRP | cg17179862 | chr17:48604000 | CGI:chr17:48607882-48608087 | promoter,exon,gene body | 1.55e-01 | 5.36e-02 | 3.02e+00 | 2.50e-03 | 6.82e-03 | 1.02e-01 |
| KIRP | cg02574073 | chr17:48605036 | CGI:chr17:48607882-48608087 | promoter | 1.73e-01 | 6.86e-02 | 2.33e+00 | 2.00e-02 | 2.67e-02 | 1.04e-01 |
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Exon skipping events with PSI in TCGA for HOXB6 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for HOXB6 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for HOXB6 |
| TFs related to HOXB6. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| HOXB6 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for HOXB6 |
| RBPs related to ES in HOXB6. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| HOXB6 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000108511 | BX284668.2,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | NRAD1,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | LINC01783,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | PWRN1,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | LINC01224,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | AC009495.3,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | LINC02688,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | AC011503.1,hsa-mir-211,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | AC009486.1,hsa-mir-4772,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | GPR176-DT,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | LINC01783,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | BX284668.2,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | Z95331.1,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | NPHP3-AS1,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | AC006116.6,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | GRASLND,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | HAGLR,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | AC106795.2,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000108511 | AL157832.1,hsa-mir-665,HOXB6 | Male-specific ceRNA | TCGA-KIRP |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs138269231 | chr17:49419949:C:T | - | 0.271118489061228 | 0.0103072058234506 | PAAD | Female-baised eQTL |
| rs146491350 | chr17:41022706:T:A | - | 0.216781271267207 | 0.00254906199657929 | LUSC | Female-baised eQTL |
| rs11867362 | chr17:43860714:A:T | - | 0.167740476629115 | 0.0309946203714869 | STAD | Female-baised eQTL |
| rs17843020 | chr17:40963690:G:A | - | 0.195055526932651 | 0.035677981900637 | STAD | Female-baised eQTL |
| rs77287979 | chr17:46977670:C:T | - | 0.168800244546 | 0.0455955966750788 | BLCA | Female-baised eQTL |
| rs2671637 | chr17:49463641:G:A | - | 0.096559280183069 | 1.37222466551662e-06 | LUAD | Female-baised eQTL |
| rs35585925 | chr17:39741957:T:C | - | 0.0816737103838408 | 3.97924063126113e-05 | LUAD | Female-baised eQTL |
| rs115638264 | chr17:44938167:C:T | - | 0.0848224868650934 | 0.00269710442030737 | LUAD | Female-baised eQTL |
| rs9904491 | chr17:49462699:C:T | - | 0.0744561364555424 | 0.00287007608994934 | LUAD | Female-baised eQTL |
| rs1316865 | chr17:49463292:T:G | - | 0.0744561364555424 | 0.00287007608994934 | LUAD | Female-baised eQTL |
| rs9906836 | chr17:49459639:G:C | - | 0.0661049748452625 | 0.00889297858543797 | LUAD | Female-baised eQTL |
| rs36079893 | chr17:39742656:A:C | - | 0.064920197896834 | 0.0106024199115196 | LUAD | Female-baised eQTL |
| rs79680842 | chr17:44935523:A:G | - | 0.073736313906596 | 0.0125125805547488 | LUAD | Female-baised eQTL |
| rs112451082 | chr17:44924001:T:C | - | 0.0661270169968689 | 0.0209670197272253 | LUAD | Female-baised eQTL |
| rs9675174 | chr17:44919297:C:A | - | 0.0643854973752427 | 0.0251389597581637 | LUAD | Female-baised eQTL |
| rs74344627 | chr17:44940457:C:T | - | 0.0684063142473874 | 0.0308297061293423 | LUAD | Female-baised eQTL |
| rs79308843 | chr17:44941193:C:A | - | 0.0684063142473874 | 0.0308297061293423 | LUAD | Female-baised eQTL |
| rs112593517 | chr17:44941402:G:A | - | 0.0684063142473874 | 0.0308297061293423 | LUAD | Female-baised eQTL |
| rs11655550 | chr17:39453870:T:C | - | 0.0375888794338297 | 0.0365415279928637 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12944434 | chr17:45122927:A:G | - | 0.0728977785090468 | 0.0449403610261205 | KIRP | Male-baised eQTL |
| rs2290433 | chr17:55822779:C:T | - | 0.136046068234181 | 0.000104171890807493 | COAD | Male-baised eQTL |
| rs2960065 | chr17:55771666:A:C | - | -0.122110850730754 | 0.00931129987382918 | COAD | Male-baised eQTL |
| rs4793154 | chr17:44809611:T:C | - | -0.0673581977089894 | 0.0192686107904911 | COAD | Male-baised eQTL |
| rs9890787 | chr17:52367371:G:A | - | 0.0491675631028745 | 0.0244239687467231 | COAD | Male-baised eQTL |
| rs35929648 | chr17:48925181:A:G | - | -0.0486746516956912 | 0.0407919059317296 | COAD | Male-baised eQTL |
| rs7218477 | chr17:44813563:A:G | - | -0.0628341469549196 | 0.0494182098297486 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg02574073 | |
| Position to Gene: promoter | |
| Male Effect: -0.0655740337731212 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg07676709 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: - | |
| Female Effect: -0.326274342600262 | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg23217463 | |
| Position to Gene: gene | |
| Male Effect: -0.32709438490896 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg07676709 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: -0.442708044394066 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg08832695 | |
| Position to Gene: gene | |
| Male Effect: -0.442708044394066 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg20591728 | |
| Position to Gene: promoter | |
| Male Effect: -0.442708044394066 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg09601584 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.284491192099067 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg05490023 | |
| Position to Gene: gene | |
| Male Effect: -0.467289405166263 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg24889708 | |
| Position to Gene: gene | |
| Male Effect: -0.18176584472574 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg22583148 | |
| Position to Gene: gene | |
| Male Effect: -0.209141895015311 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg07676709 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: -0.24614844780254 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg08832695 | |
| Position to Gene: gene | |
| Male Effect: -0.228115983692497 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg23217463 | |
| Position to Gene: gene | |
| Male Effect: -0.210611335986514 | |
| Female Effect: - | |
 | Gene ID: ENSG00000108511 |
| CpG Site: cg07318128 | |
| Position to Gene: promoter | |
| Male Effect: -0.230450931326344 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg02574073 | chr17:48605036 | promoter | -0.0655740337731212 | 9.13738434461955e-05 | -0.33461805245863674 | 3.731299862171703e-07 | LUAD |
| cg23217463 | chr17:48599611 | gene | -0.32709438490896 | 7.31635253059209e-07 | -0.3891871231047515 | 2.2726532732919016e-09 | STAD |
| cg07676709 | chr17:48596080 | gene,exon,UTR | -0.442708044394066 | 2.20679744799524e-06 | -0.377946636781306 | 7.033831371199278e-09 | STAD |
| cg08832695 | chr17:48599013 | gene | -0.442708044394066 | 2.20679744799524e-06 | -0.377946636781306 | 7.033831371199278e-09 | STAD |
| cg20591728 | chr17:48606244 | promoter | -0.442708044394066 | 2.20679744799524e-06 | -0.377946636781306 | 7.033831371199278e-09 | STAD |
| cg09601584 | chr17:48596548 | gene,exon,CDS | -0.284491192099067 | 2.94833746812048e-05 | -0.34629595066317337 | 1.3557608370103007e-07 | STAD |
| cg05490023 | chr17:48600598 | gene | -0.467289405166263 | 3.66794450693871e-34 | -0.6622300412235467 | 3.145830905738531e-38 | SKCM |
| cg24889708 | chr17:48601357 | gene | -0.18176584472574 | 2.01061895527918e-12 | -0.4494845431804432 | 6.30250378834072e-16 | SKCM |
| cg22583148 | chr17:48596679 | gene | -0.209141895015311 | 1.3115590008489e-59 | -0.7973388602744532 | 2.044432820097904e-68 | BLCA |
| cg07676709 | chr17:48596080 | gene,exon,UTR | -0.24614844780254 | 3.79482775295807e-59 | -0.7930534130509712 | 3.40897162026327e-67 | BLCA |
| cg08832695 | chr17:48599013 | gene | -0.228115983692497 | 6.79549655129781e-48 | -0.7390863112382267 | 6.293867159034348e-54 | BLCA |
| cg23217463 | chr17:48599611 | gene | -0.210611335986514 | 1.19806345932761e-44 | -0.7313397825468486 | 2.721075459970683e-52 | BLCA |
| cg07318128 | chr17:48606444 | promoter | -0.230450931326344 | 1.00362921232729e-05 | -0.3089924491240601 | 3.597096183122504e-08 | BLCA |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg07676709 | chr17:48596080 | gene,exon,UTR | -0.326274342600262 | 2.09639627599718e-21 | -0.5918240646365484 | 1.7241505517060566e-25 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of HOXB6 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
