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Gene: ENSG00000107864 |
Summary for CPEB3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000107864 | Gene symbol | CPEB3 |
| Gene name | cytoplasmic polyadenylation element binding protein 3 | |
| HGNC | 21746 | |
| Entrez ID | 22849 | |
| Gene type | protein_coding | |
| Synonyms | CPEB3|KIAA0940 | |
| UniProtAcc | Q8NE35 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for CPEB3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CPEB3 | 5.59e+02 | -1.08e+00 | 1.44e-01 | -7.50e+00 | 6.58e-14 | 6.66e-13 | KIRP |
| CPEB3 | 8.32e+02 | -1.48e+00 | 2.87e-01 | -5.15e+00 | 2.59e-07 | 7.83e-06 | ESCA |
| CPEB3 | 8.74e+02 | -3.08e+00 | 4.54e-01 | -6.77e+00 | 1.28e-11 | 2.68e-10 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
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Sex-biased somatic mutation for CPEB3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for CPEB3 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
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Exon skipping events with PSI in TCGA for CPEB3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for CPEB3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for CPEB3 |
| TFs related to CPEB3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LAML | DUXA | CPEB3 | 4.36e+00 | 1.66e-02 | 5.13e+00 | 9.80e-01 | Female-biased |
| LAML | NKX3-2 | CPEB3 | 3.83e+00 | 8.74e-03 | 4.77e+00 | 9.86e-01 | Female-biased |
| LAML | POU4F1 | CPEB3 | 3.74e+00 | 7.24e-03 | 4.72e+00 | 9.87e-01 | Female-biased |
| LAML | POU4F3 | CPEB3 | 3.90e+00 | 8.96e-03 | 4.83e+00 | 9.86e-01 | Female-biased |
| SARC | STAT2 | CPEB3 | 4.16e+00 | 9.80e-01 | 3.55e+00 | 7.30e-03 | Male-biased |
| CPEB3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for CPEB3 |
| RBPs related to ES in CPEB3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KICH | SART3 | exon_skip_52148 | 8.95e+00 | 9.84e-01 | 8.64e+00 | 1.18e-02 | Male-biased |
| CPEB3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000107864 | LINC01213,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC027307.3,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | TPRG1-AS1,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | LINC02688,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | HAGLR,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | DANCR,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC090579.1,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AL450326.1,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AP001107.9,hsa-mir-338,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | TEX41,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | LINC01354,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | LINC02798,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AL160286.2,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | LINC01915,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC008771.1,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | TGFB2-AS1,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC083843.2,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | MAP4K3-DT,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC025811.1,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC026124.2,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | DHRS4-AS1,hsa-mir-340,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AP001107.9,hsa-mir-34c,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC016705.2,hsa-mir-34c,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC005920.3,hsa-mir-34c,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | TEX41,hsa-mir-363,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AC044810.2,hsa-mir-363,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | LINC01915,hsa-mir-363,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | RORA-AS1,hsa-mir-483,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | PPFIA2-AS1,hsa-mir-483,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | DHRS4-AS1,hsa-mir-483,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AP000688.2,hsa-mir-497,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | TEX41,hsa-mir-497,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
| ENSG00000107864 | AL162377.1,hsa-mir-497,CPEB3 | Male-specific ceRNA | TCGA-KIRP |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs787697 | chr10:93345127:C:T | - | 0.104339333282948 | 0.0382223468199351 | LIHC | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs498979 | chr10:82857121:T:C | - | 0.0741804828981706 | 0.0110163627383984 | LIHC | Male-baised eQTL |
| rs342400 | chr10:82859865:T:G | - | 0.0632272126480166 | 0.0356571992986588 | LIHC | Male-baised eQTL |
| rs342401 | chr10:82859603:T:C | - | 0.0539648924557648 | 0.0464653966181773 | LIHC | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000107864 |
| CpG Site: cg04889043 | |
| Position to Gene: gene | |
| Male Effect: -0.130742084944663 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg04889043 | chr10:92123088 | gene | -0.130742084944663 | 3.34057275945893e-06 | -0.3768770464426163 | 6.1702711839549796e-09 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of CPEB3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000107864 | CPEB3 | C2239176 | Liver carcinoma | 1 | CTD_human |
