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Gene: ENSG00000106571 |
Summary for GLI3 |
Gene summary |
| Gene information | Ensembl ID | ENSG00000106571 | Gene symbol | GLI3 |
| Gene name | GLI family zinc finger 3 | |
| HGNC | 4319 | |
| Entrez ID | 2737 | |
| Gene type | protein_coding | |
| Synonyms | GLI3|PAP-A|PAPA|PAPA1|PAPB|ACLS|PPDIV | |
| UniProtAcc | P10071 |
Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for GLI3 |
AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
Landscape of gene expressions across multiple cancer types. |
Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| GLI3 | 8.71e+02 | -1.30e+00 | 4.27e-01 | -3.04e+00 | 2.40e-03 | 1.11e-02 | STAD |
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Sex-biased somatic mutation for GLI3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for GLI3 |
Landscape of DNA methylation across multiple cancer types. |
Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg25726664 | chr7:42238208 | CGI:chr7:42236404-42237855 | promoter | 2.89e-01 | 1.82e-01 | 2.88e+00 | 3.93e-03 | 9.49e-03 | 1.07e-01 |
Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg02483271 | chr7:42238351 | CGI:chr7:42236404-42237855 | promoter | 2.70e-01 | 3.76e-01 | -4.70e+00 | 2.55e-06 | 8.22e-06 | -1.06e-01 |
| LUSC | cg02483271 | chr7:42238351 | CGI:chr7:42236404-42237855 | promoter | 2.76e-01 | 3.80e-01 | -3.10e+00 | 1.94e-03 | 4.09e-03 | -1.04e-01 |
| LUSC | cg26557756 | chr7:42238497 | CGI:chr7:42236404-42237855 | promoter | 5.91e-01 | 7.87e-01 | -2.57e+00 | 1.01e-02 | 1.40e-02 | -1.95e-01 |
| COAD | cg10569039 | chr7:42237445 | CGI:chr7:42236404-42237855 | promoter,gene body | 1.96e-01 | 4.22e-02 | 3.14e+00 | 1.66e-03 | 3.40e-03 | 1.54e-01 |
| COAD | cg24497732 | chr7:42238478 | CGI:chr7:42236404-42237855 | promoter | 6.67e-01 | 5.64e-01 | 3.89e+00 | 1.01e-04 | 3.54e-04 | 1.03e-01 |
| COAD | cg26557756 | chr7:42238497 | CGI:chr7:42236404-42237855 | promoter | 8.62e-01 | 7.12e-01 | 4.63e+00 | 3.65e-06 | 2.83e-05 | 1.50e-01 |
| CHOL | cg24497732 | chr7:42238478 | CGI:chr7:42236404-42237855 | promoter | 5.43e-01 | 2.98e-01 | 2.65e+00 | 7.96e-03 | 1.92e-02 | 2.46e-01 |
| CHOL | cg16524701 | chr7:42236002 | CGI:chr7:42236404-42237855 | promoter,gene body | 3.18e-01 | 1.40e-01 | 2.21e+00 | 2.70e-02 | 3.50e-02 | 1.78e-01 |
| CHOL | cg17588800 | chr7:42238468 | CGI:chr7:42236404-42237855 | promoter | 5.23e-01 | 2.90e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 2.33e-01 |
Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg25726664 | chr7:42238208 | CGI:chr7:42236404-42237855 | promoter | 2.59e-01 | 6.17e-02 | 7.98e+00 | 1.46e-15 | 5.54e-15 | 1.97e-01 |
| BRCA | cg24497732 | chr7:42238478 | CGI:chr7:42236404-42237855 | promoter | 4.62e-01 | 3.18e-01 | 8.19e+00 | 2.63e-16 | 1.06e-15 | 1.44e-01 |
| BRCA | cg02483271 | chr7:42238351 | CGI:chr7:42236404-42237855 | promoter | 3.53e-01 | 2.21e-01 | 6.19e+00 | 5.93e-10 | 1.47e-09 | 1.31e-01 |
| BRCA | cg17588800 | chr7:42238468 | CGI:chr7:42236404-42237855 | promoter | 4.56e-01 | 3.01e-01 | 8.20e+00 | 2.45e-16 | 9.90e-16 | 1.56e-01 |
| BRCA | cg14396995 | chr7:42238490 | CGI:chr7:42236404-42237855 | promoter | 4.33e-01 | 2.42e-01 | 6.55e+00 | 5.88e-11 | 1.57e-10 | 1.91e-01 |
| BRCA | cg26557756 | chr7:42238497 | CGI:chr7:42236404-42237855 | promoter | 5.75e-01 | 3.65e-01 | 4.09e+00 | 4.34e-05 | 6.77e-05 | 2.09e-01 |
| KIRC | cg26557756 | chr7:42238497 | CGI:chr7:42236404-42237855 | promoter | 7.85e-01 | 6.59e-01 | 2.76e+00 | 5.85e-03 | 1.21e-02 | 1.26e-01 |
| LUAD | cg16524701 | chr7:42236002 | CGI:chr7:42236404-42237855 | promoter,gene body | 2.78e-01 | 1.41e-01 | 3.32e+00 | 8.85e-04 | 2.95e-03 | 1.37e-01 |
| THCA | cg25726664 | chr7:42238208 | CGI:chr7:42236404-42237855 | promoter | 3.24e-01 | 1.74e-01 | 2.97e+00 | 2.97e-03 | 5.38e-03 | 1.49e-01 |
| LIHC | cg25726664 | chr7:42238208 | CGI:chr7:42236404-42237855 | promoter | 2.89e-01 | 5.42e-02 | 3.73e+00 | 1.94e-04 | 6.37e-04 | 2.35e-01 |
| LIHC | cg17588800 | chr7:42238468 | CGI:chr7:42236404-42237855 | promoter | 4.39e-01 | 2.73e-01 | 3.35e+00 | 8.08e-04 | 1.91e-03 | 1.66e-01 |
| LIHC | cg26557756 | chr7:42238497 | CGI:chr7:42236404-42237855 | promoter | 5.73e-01 | 4.29e-01 | 2.43e+00 | 1.52e-02 | 1.94e-02 | 1.44e-01 |
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Exon skipping events with PSI in TCGA for GLI3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for GLI3 |
| ∗Please access CAeditome for RNA editing annotation. |
Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for GLI3 |
TFs related to GLI3.∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DLBC | ZNF418 | GLI3 | 3.67e+00 | 9.47e-03 | 4.58e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF879 | GLI3 | 3.33e+00 | 8.87e-03 | 4.25e+00 | 9.81e-01 | Female-biased |
GLI3 related gene.∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for GLI3 |
RBPs related to ES in GLI3.∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
GLI3 related ES.∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000106571 | FAM66C,hsa-mir-223,GLI3 | Female-specific ceRNA | TCGA-STAD |
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Sex-biased eQTL regulation of gene |
Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs191953 | chr7:32385625:T:A | - | -0.0689076758974005 | 0.0281072801164786 | THCA | Female-baised eQTL |
| rs11979793 | chr7:42298727:T:C | - | 0.117273161783797 | 0.0488843296136405 | SARC | Female-baised eQTL |
| rs73329134 | chr7:34032268:C:T | - | 0.0881694205804224 | 0.0231278881381834 | KIRC | Female-baised eQTL |
| rs1019002 | chr7:50742885:T:C | - | -0.088017987606073 | 0.0233388218415965 | KIRC | Female-baised eQTL |
| rs73329157 | chr7:34049320:C:T | - | 0.0860252404210199 | 0.0374344040028688 | KIRC | Female-baised eQTL |
| rs1004590 | chr7:33793071:G:A | - | -0.0731520450918774 | 0.0386613251809551 | KIRC | Female-baised eQTL |
| rs1024532 | chr7:50746273:C:A | - | -0.0835417448355795 | 0.041716377406182 | KIRC | Female-baised eQTL |
| rs6978627 | chr7:50746858:A:C | - | -0.0811028581580361 | 0.0483030693088841 | KIRC | Female-baised eQTL |
| rs6945302 | chr7:50746899:T:C | - | -0.0811028581580361 | 0.0483030693088841 | KIRC | Female-baised eQTL |
| rs3800999 | chr7:50743445:T:C | - | -0.0810501375797801 | 0.0489866456263447 | KIRC | Female-baised eQTL |
| rs17169628 | chr7:34040940:G:A | - | 0.0808628669015106 | 0.0497182045767638 | KIRC | Female-baised eQTL |
| rs17161149 | chr7:32300665:T:C | - | 0.199312718387999 | 0.00624013127888692 | BLCA | Female-baised eQTL |
| rs13235554 | chr7:32302682:A:G | - | 0.199312718387999 | 0.00624013127888692 | BLCA | Female-baised eQTL |
| rs13225848 | chr7:32302998:T:C | - | 0.199312718387999 | 0.00624013127888692 | BLCA | Female-baised eQTL |
| rs7790355 | chr7:32296973:C:T | - | 0.198800797848201 | 0.00788837512817299 | BLCA | Female-baised eQTL |
| rs6952052 | chr7:32303281:C:G | - | 0.197504116002483 | 0.0103464107363816 | BLCA | Female-baised eQTL |
| rs28844920 | chr7:32311853:C:G | - | 0.197504116002483 | 0.0103464107363816 | BLCA | Female-baised eQTL |
| rs6943670 | chr7:32319565:G:C | - | 0.198331229775314 | 0.0182741341399028 | BLCA | Female-baised eQTL |
| rs13235908 | chr7:32319877:C:T | - | 0.198331229775314 | 0.0182741341399028 | BLCA | Female-baised eQTL |
| rs58174156 | chr7:32299236:A:T | - | 0.197834372743353 | 0.0227552761090684 | BLCA | Female-baised eQTL |
| rs59910515 | chr7:32292299:T:C | - | 0.195731034301422 | 0.0261654510189239 | BLCA | Female-baised eQTL |
| rs71530587 | chr7:32322289:T:G | - | 0.19743512704071 | 0.0278489174688781 | BLCA | Female-baised eQTL |
| rs13244617 | chr7:32322658:G:A | - | 0.19743512704071 | 0.0278489174688781 | BLCA | Female-baised eQTL |
| rs12536248 | chr7:32329684:A:G | - | 0.19743512704071 | 0.0278489174688781 | BLCA | Female-baised eQTL |
| rs12701215 | chr7:32332064:A:C | - | 0.19743512704071 | 0.0278489174688781 | BLCA | Female-baised eQTL |
| rs12536117 | chr7:32306260:C:T | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs60931903 | chr7:32307083:A:C | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs13237692 | chr7:32307934:G:C | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs74609155 | chr7:32309401:C:T | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs36199116 | chr7:32310705:G:A | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs75031635 | chr7:32312143:C:T | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs78945330 | chr7:32312955:G:A | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs10951329 | chr7:32313795:C:A | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs35199208 | chr7:32317261:T:G | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs35368938 | chr7:32317366:C:T | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs12531102 | chr7:32320416:T:C | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs12538782 | chr7:32320442:G:A | - | 0.196874402708567 | 0.0285125888115316 | BLCA | Female-baised eQTL |
| rs6462842 | chr7:38447025:T:G | - | 0.183321426480883 | 0.0312591639207381 | BLCA | Female-baised eQTL |
| rs13312286 | chr7:32298194:G:T | - | 0.196429125578336 | 0.0351121300375474 | BLCA | Female-baised eQTL |
| rs10250232 | chr7:38444765:T:A | - | 0.17584643052803 | 0.0454087738985375 | BLCA | Female-baised eQTL |
| rs10238666 | chr7:38445523:G:A | - | 0.17584643052803 | 0.0454087738985375 | BLCA | Female-baised eQTL |
| rs62447353 | chr7:48611637:T:C | - | 0.0872332640598804 | 4.04746259199954e-07 | LUAD | Female-baised eQTL |
| rs34598210 | chr7:48606816:C:T | - | 0.0852845104907616 | 6.87599040250056e-07 | LUAD | Female-baised eQTL |
| rs75913078 | chr7:48610113:C:T | - | 0.0852393567754757 | 7.08111919203132e-07 | LUAD | Female-baised eQTL |
| rs12718292 | chr7:48646935:T:C | - | 0.0828817321238215 | 1.045675325553e-06 | LUAD | Female-baised eQTL |
| rs35483521 | chr7:48651087:A:G | - | 0.0828817321238215 | 1.045675325553e-06 | LUAD | Female-baised eQTL |
| rs62448770 | chr7:48681560:C:T | - | 0.0812576397716338 | 1.24182444410951e-06 | LUAD | Female-baised eQTL |
| rs12718290 | chr7:48636634:G:A | - | 0.0814270352318824 | 1.47989890312197e-06 | LUAD | Female-baised eQTL |
| rs13234438 | chr7:48681972:A:G | - | 0.0761255563392597 | 5.61293978591087e-06 | LUAD | Female-baised eQTL |
| rs13234500 | chr7:48591572:G:A | - | 0.078367520607184 | 6.06966688300678e-06 | LUAD | Female-baised eQTL |
| rs34021932 | chr7:48593634:T:A | - | 0.078367520607184 | 6.06966688300678e-06 | LUAD | Female-baised eQTL |
| rs62447359 | chr7:48650492:G:A | - | 0.0729352305571757 | 1.40878030367158e-05 | LUAD | Female-baised eQTL |
| rs2952755 | chr7:52131475:T:C | - | -0.0959311943380424 | 1.49397246626298e-05 | LUAD | Female-baised eQTL |
| rs2952756 | chr7:52132217:C:T | - | -0.0959311943380424 | 1.49397246626298e-05 | LUAD | Female-baised eQTL |
| rs79961760 | chr7:49378312:A:C | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs76842746 | chr7:49378838:C:T | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs74798873 | chr7:49380382:G:A | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs74468231 | chr7:49380706:G:A | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs3850662 | chr7:49384994:T:C | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs76982893 | chr7:49386032:T:G | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs2217458 | chr7:49391948:T:C | - | 0.0740940904067864 | 1.66362653019444e-05 | LUAD | Female-baised eQTL |
| rs4917054 | chr7:49398493:C:T | - | 0.0728945863886623 | 1.68566670024369e-05 | LUAD | Female-baised eQTL |
| rs115430583 | chr7:49379798:C:T | - | 0.0724357486471559 | 2.72454584448374e-05 | LUAD | Female-baised eQTL |
| rs7777085 | chr7:49389561:C:G | - | 0.071524397958205 | 3.01431155260953e-05 | LUAD | Female-baised eQTL |
| rs6974462 | chr7:52136576:T:C | - | -0.0892505300288341 | 5.41551614633894e-05 | LUAD | Female-baised eQTL |
| rs12530719 | chr7:52138101:C:G | - | -0.086381505448763 | 9.09111746023914e-05 | LUAD | Female-baised eQTL |
| rs4425713 | chr7:52142155:C:T | - | -0.086381505448763 | 9.09111746023914e-05 | LUAD | Female-baised eQTL |
| rs35302464 | chr7:48590968:G:A | - | 0.0666898969963175 | 0.000121901931019062 | LUAD | Female-baised eQTL |
| rs13223000 | chr7:48591283:A:C | - | 0.0666898969963175 | 0.000121901931019062 | LUAD | Female-baised eQTL |
| rs2952758 | chr7:52107812:C:T | - | -0.0765044858407037 | 0.000376618495047292 | LUAD | Female-baised eQTL |
| rs13238053 | chr7:48680144:G:A | - | 0.056058564209595 | 0.00059434040370525 | LUAD | Female-baised eQTL |
| rs17092951 | chr7:48749881:A:T | - | 0.0661347199898814 | 0.00124204592886233 | LUAD | Female-baised eQTL |
| rs12669631 | chr7:48767542:A:T | - | 0.0671516352523754 | 0.00129598916657624 | LUAD | Female-baised eQTL |
| rs1557953 | chr7:47041430:T:C | - | 0.0519137073955156 | 0.00173327261272579 | LUAD | Female-baised eQTL |
| rs142578108 | chr7:34802013:G:A | - | 0.0454273852822256 | 0.00197663604342441 | LUAD | Female-baised eQTL |
| rs79779019 | chr7:34802031:G:C | - | 0.0454273852822256 | 0.00197663604342441 | LUAD | Female-baised eQTL |
| rs34224851 | chr7:34822868:G:A | - | 0.043701779356715 | 0.00293958405782113 | LUAD | Female-baised eQTL |
| rs17199659 | chr7:34812217:T:C | - | 0.0433089720535423 | 0.00316927638641825 | LUAD | Female-baised eQTL |
| rs62462949 | chr7:34807578:T:C | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs17199395 | chr7:34808619:G:C | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs17789432 | chr7:34813104:G:A | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs17789456 | chr7:34813515:T:C | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs17789480 | chr7:34813865:T:A | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs35738101 | chr7:34814574:G:C | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs62462955 | chr7:34820941:G:A | - | 0.0432714190189138 | 0.00325296950596214 | LUAD | Female-baised eQTL |
| rs35441532 | chr7:34798694:C:T | - | 0.0432767350593654 | 0.00328187370766623 | LUAD | Female-baised eQTL |
| rs62462930 | chr7:34799030:C:T | - | 0.0432767350593654 | 0.00328187370766623 | LUAD | Female-baised eQTL |
| rs201585882 | chr7:34802352:T:A | - | 0.0432767350593654 | 0.00328187370766623 | LUAD | Female-baised eQTL |
| rs62462947 | chr7:34804327:G:A | - | 0.0432767350593654 | 0.00328187370766623 | LUAD | Female-baised eQTL |
| rs62462948 | chr7:34805926:G:A | - | 0.0432767350593654 | 0.00328187370766623 | LUAD | Female-baised eQTL |
| rs1585255 | chr7:34806425:A:G | - | 0.0432767350593654 | 0.00328187370766623 | LUAD | Female-baised eQTL |
| rs17789287 | chr7:34810691:T:A | - | 0.0431963767582583 | 0.00331121397752537 | LUAD | Female-baised eQTL |
| rs62447338 | chr7:48586598:T:A | - | 0.0500599678460492 | 0.00347399492296693 | LUAD | Female-baised eQTL |
| rs17777040 | chr7:34720853:G:T | - | 0.0433584914082082 | 0.00361548177894999 | LUAD | Female-baised eQTL |
| rs62447337 | chr7:48586422:C:G | - | 0.049889222114741 | 0.00366289213580568 | LUAD | Female-baised eQTL |
| rs62462889 | chr7:34775347:G:A | - | 0.0430749246544281 | 0.00372954897039342 | LUAD | Female-baised eQTL |
| rs62462890 | chr7:34779511:T:A | - | 0.0428669261022062 | 0.0039043893028635 | LUAD | Female-baised eQTL |
| rs35928424 | chr7:34780937:G:A | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs62462893 | chr7:34781860:G:A | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs62462894 | chr7:34782205:A:G | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs62462896 | chr7:34784041:C:T | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs62462897 | chr7:34784394:G:A | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs62462925 | chr7:34789409:G:C | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs35654624 | chr7:34794829:C:A | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs34980042 | chr7:34796713:G:A | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs35963851 | chr7:34797285:A:G | - | 0.0425202552766615 | 0.00403951888069968 | LUAD | Female-baised eQTL |
| rs17199458 | chr7:34810017:C:G | - | 0.0424412041022664 | 0.00407819103064094 | LUAD | Female-baised eQTL |
| rs62462891 | chr7:34780141:C:T | - | 0.0423334392333612 | 0.00453634198481416 | LUAD | Female-baised eQTL |
| rs17170682 | chr7:36723278:T:C | - | 0.0449524290094954 | 0.00488065381872482 | LUAD | Female-baised eQTL |
| rs17198163 | chr7:34724786:G:A | - | 0.0415249366683745 | 0.00573918320946005 | LUAD | Female-baised eQTL |
| rs17198065 | chr7:34722945:C:T | - | 0.0414669584425885 | 0.00581115343109718 | LUAD | Female-baised eQTL |
| rs17198093 | chr7:34723264:A:G | - | 0.0414669584425885 | 0.00581115343109718 | LUAD | Female-baised eQTL |
| rs11975122 | chr7:34725447:T:C | - | 0.0414669584425885 | 0.00581115343109718 | LUAD | Female-baised eQTL |
| rs17198254 | chr7:34727813:G:A | - | 0.0414669584425885 | 0.00581115343109718 | LUAD | Female-baised eQTL |
| rs28496672 | chr7:35390273:C:T | - | 0.0795104573569201 | 0.00609186570361078 | LUAD | Female-baised eQTL |
| rs17170996 | chr7:35391749:T:C | - | 0.0795104573569201 | 0.00609186570361078 | LUAD | Female-baised eQTL |
| rs2893505 | chr7:35402014:C:T | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs2893506 | chr7:35402061:C:T | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs28707305 | chr7:35402734:G:A | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs28651941 | chr7:35402779:C:G | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs12666614 | chr7:35403313:G:C | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs10232645 | chr7:35404117:G:A | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs10266475 | chr7:35405568:A:T | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs28401291 | chr7:35407652:C:A | - | 0.0794891689551376 | 0.00610651147836148 | LUAD | Female-baised eQTL |
| rs113271899 | chr7:34766613:C:T | - | 0.0410001424733929 | 0.00629065840443679 | LUAD | Female-baised eQTL |
| rs6951760 | chr7:39756630:G:A | - | 0.0391290273448799 | 0.00657227788139504 | LUAD | Female-baised eQTL |
| rs17788843 | chr7:34757754:G:A | - | 0.0403793746078092 | 0.00732066828747782 | LUAD | Female-baised eQTL |
| rs62462895 | chr7:34782789:A:G | - | 0.0387163020177738 | 0.00750752783388283 | LUAD | Female-baised eQTL |
| rs17170523 | chr7:36182482:T:A | - | 0.0686576041517042 | 0.00797458021120947 | LUAD | Female-baised eQTL |
| rs10227265 | chr7:35385428:A:T | - | 0.0765126427849627 | 0.0081971222570131 | LUAD | Female-baised eQTL |
| rs73096159 | chr7:35387009:T:C | - | 0.0765126427849627 | 0.0081971222570131 | LUAD | Female-baised eQTL |
| rs10258686 | chr7:35387499:T:C | - | 0.0765126427849627 | 0.0081971222570131 | LUAD | Female-baised eQTL |
| rs10258844 | chr7:35387650:T:C | - | 0.0765126427849627 | 0.0081971222570131 | LUAD | Female-baised eQTL |
| rs12669342 | chr7:35388314:C:T | - | 0.0765126427849627 | 0.0081971222570131 | LUAD | Female-baised eQTL |
| rs12673537 | chr7:35388358:A:G | - | 0.0765126427849627 | 0.0081971222570131 | LUAD | Female-baised eQTL |
| rs12701769 | chr7:39814031:A:C | - | 0.040191186256002 | 0.00820165398721837 | LUAD | Female-baised eQTL |
| rs1016303 | chr7:39815541:T:C | - | 0.040191186256002 | 0.00820165398721837 | LUAD | Female-baised eQTL |
| rs13223851 | chr7:39817993:G:A | - | 0.040191186256002 | 0.00820165398721837 | LUAD | Female-baised eQTL |
| rs34997720 | chr7:39819707:A:G | - | 0.040191186256002 | 0.00820165398721837 | LUAD | Female-baised eQTL |
| rs12672982 | chr7:35385318:T:C | - | 0.0743709700091816 | 0.00970181175495105 | LUAD | Female-baised eQTL |
| rs62462885 | chr7:34755588:G:C | - | 0.0390625243146148 | 0.00973700749438091 | LUAD | Female-baised eQTL |
| rs12718908 | chr7:50780847:T:A | - | 0.0742973594732071 | 0.0105952568930835 | LUAD | Female-baised eQTL |
| rs17789096 | chr7:34771704:G:A | - | 0.0389098875640499 | 0.0106820143054191 | LUAD | Female-baised eQTL |
| rs12701768 | chr7:39813317:G:A | - | 0.0392290882541045 | 0.010930469208309 | LUAD | Female-baised eQTL |
| rs13235149 | chr7:39813749:A:G | - | 0.0392290882541045 | 0.010930469208309 | LUAD | Female-baised eQTL |
| rs76011982 | chr7:34766880:A:G | - | 0.0387891030104984 | 0.0110485551132666 | LUAD | Female-baised eQTL |
| rs57333507 | chr7:34541030:G:A | - | 0.0643100350416782 | 0.0115914392933203 | LUAD | Female-baised eQTL |
| rs76775551 | chr7:34545741:G:T | - | 0.0643100350416782 | 0.0115914392933203 | LUAD | Female-baised eQTL |
| rs76088994 | chr7:34526436:G:A | - | 0.0642484753779077 | 0.0117696228131774 | LUAD | Female-baised eQTL |
| rs73324703 | chr7:34651176:G:A | - | 0.0528420565283486 | 0.0123676914993324 | LUAD | Female-baised eQTL |
| rs917199 | chr7:39818779:C:T | - | 0.0386917670107784 | 0.0125588351474031 | LUAD | Female-baised eQTL |
| rs34917509 | chr7:39761687:C:T | - | 0.0387807295748055 | 0.0128638407397103 | LUAD | Female-baised eQTL |
| rs9691839 | chr7:34562308:C:T | - | 0.062689516886086 | 0.0137675557717456 | LUAD | Female-baised eQTL |
| rs17753324 | chr7:42139946:G:T | gene | 0.0378177736024103 | 0.0143925901204863 | LUAD | Female-baised eQTL |
| rs17198982 | chr7:34757193:A:T | - | 0.0357816887280095 | 0.0154627299718649 | LUAD | Female-baised eQTL |
| rs13223212 | chr7:39752657:C:T | - | 0.0381249132066663 | 0.0162419088623071 | LUAD | Female-baised eQTL |
| rs75821067 | chr7:48232786:G:C | - | 0.0516196499449471 | 0.018512209061248 | LUAD | Female-baised eQTL |
| rs79276075 | chr7:35641331:G:T | - | 0.0690472039879161 | 0.0199728163223056 | LUAD | Female-baised eQTL |
| rs115644728 | chr7:35642571:A:G | - | 0.0690472039879161 | 0.0199728163223056 | LUAD | Female-baised eQTL |
| rs4142249 | chr7:35644901:T:C | - | 0.0690472039879161 | 0.0199728163223056 | LUAD | Female-baised eQTL |
| rs75800265 | chr7:35645337:C:A | - | 0.0690472039879161 | 0.0199728163223056 | LUAD | Female-baised eQTL |
| rs78393183 | chr7:35645636:T:C | - | 0.0690472039879161 | 0.0199728163223056 | LUAD | Female-baised eQTL |
| rs7795729 | chr7:48764173:T:C | - | 0.0505136929959597 | 0.0212622789491584 | LUAD | Female-baised eQTL |
| rs74868197 | chr7:35374127:T:A | - | 0.0715464995068349 | 0.0213870900567998 | LUAD | Female-baised eQTL |
| rs62464163 | chr7:34427980:C:G | - | 0.0696752035057891 | 0.024034046821891 | LUAD | Female-baised eQTL |
| rs1717731 | chr7:38061803:T:C | - | 0.0413936815970361 | 0.0255308484836893 | LUAD | Female-baised eQTL |
| rs2237461 | chr7:50661984:A:G | - | -0.0387899397960811 | 0.0262222229488979 | LUAD | Female-baised eQTL |
| rs10247437 | chr7:35182774:C:T | - | 0.0319218246946718 | 0.0268640543164707 | LUAD | Female-baised eQTL |
| rs2609232 | chr7:34652451:A:C | - | 0.0360560994014244 | 0.0272427357451749 | LUAD | Female-baised eQTL |
| rs17239509 | chr7:43773139:T:A | - | 0.0579292802524869 | 0.027458398693709 | LUAD | Female-baised eQTL |
| rs76189875 | chr7:35793233:A:G | - | 0.0613846452068686 | 0.0300066896932073 | LUAD | Female-baised eQTL |
| rs77266527 | chr7:35798329:T:C | - | 0.0613846452068686 | 0.0300066896932073 | LUAD | Female-baised eQTL |
| rs2280497 | chr7:45708334:A:G | - | 0.0351065305058867 | 0.0310596378655416 | LUAD | Female-baised eQTL |
| rs6962860 | chr7:35623979:T:C | - | 0.0650846913053614 | 0.0324317314397192 | LUAD | Female-baised eQTL |
| rs2221657 | chr7:50072810:C:G | - | -0.0406165212473658 | 0.0335971338607004 | LUAD | Female-baised eQTL |
| rs79735030 | chr7:35751990:A:G | - | 0.0590823966910596 | 0.0341764022972828 | LUAD | Female-baised eQTL |
| rs60781338 | chr7:45693244:T:G | - | 0.0343202432174578 | 0.0342415423540281 | LUAD | Female-baised eQTL |
| rs12534368 | chr7:34622222:C:T | - | 0.0395881098594514 | 0.0347697349910905 | LUAD | Female-baised eQTL |
| rs17699657 | chr7:35777962:T:C | - | 0.0597349919006837 | 0.0347834248074927 | LUAD | Female-baised eQTL |
| rs7805532 | chr7:48763970:G:C | - | 0.0473211369197167 | 0.0348542768323685 | LUAD | Female-baised eQTL |
| rs10272932 | chr7:34639632:C:T | - | 0.0346140590709811 | 0.035355168557402 | LUAD | Female-baised eQTL |
| rs17767309 | chr7:35781894:C:T | - | 0.0596444628976725 | 0.0354073100730553 | LUAD | Female-baised eQTL |
| rs80297131 | chr7:35720280:G:A | - | 0.0619921275460607 | 0.0360468217647833 | LUAD | Female-baised eQTL |
| rs67552469 | chr7:36696228:T:C | - | 0.0457255922385859 | 0.0373670375075642 | LUAD | Female-baised eQTL |
| rs2530540 | chr7:34652391:C:T | - | 0.0344420344636338 | 0.037400163645904 | LUAD | Female-baised eQTL |
| rs112269061 | chr7:35664803:C:A | - | 0.0629985732363742 | 0.0382103596831673 | LUAD | Female-baised eQTL |
| rs79442355 | chr7:35672535:T:C | - | 0.0629985732363742 | 0.0382103596831673 | LUAD | Female-baised eQTL |
| rs75133782 | chr7:35676259:C:T | - | 0.0629985732363742 | 0.0382103596831673 | LUAD | Female-baised eQTL |
| rs17699339 | chr7:35690208:T:C | - | 0.0629985732363742 | 0.0382103596831673 | LUAD | Female-baised eQTL |
| rs2302032 | chr7:43758693:G:T | - | 0.0542916275415751 | 0.0384121616383887 | LUAD | Female-baised eQTL |
| rs60897458 | chr7:43795040:G:A | - | 0.0542703602706676 | 0.0387387616157477 | LUAD | Female-baised eQTL |
| rs17766832 | chr7:35647527:G:A | - | 0.0629129434830173 | 0.0388243571045775 | LUAD | Female-baised eQTL |
| rs56737414 | chr7:35778612:T:G | - | 0.0575700163826691 | 0.0393689267581842 | LUAD | Female-baised eQTL |
| rs62461102 | chr7:43738896:T:C | - | 0.0541327364084006 | 0.0395247053736657 | LUAD | Female-baised eQTL |
| rs62461103 | chr7:43739194:C:T | - | 0.0540719807639127 | 0.0400537114007981 | LUAD | Female-baised eQTL |
| rs62461101 | chr7:43736788:A:T | - | 0.0533031772106032 | 0.041440671312838 | LUAD | Female-baised eQTL |
| rs12673353 | chr7:43738532:A:G | - | 0.0532833634801264 | 0.0416919672108158 | LUAD | Female-baised eQTL |
| rs12669403 | chr7:35772930:G:A | - | 0.0571672974817033 | 0.0421152188582687 | LUAD | Female-baised eQTL |
| rs12669382 | chr7:35793984:T:C | - | 0.0571462510013968 | 0.0423595407729568 | LUAD | Female-baised eQTL |
| rs144157529 | chr7:35798703:C:T | - | 0.0571462510013968 | 0.0423595407729568 | LUAD | Female-baised eQTL |
| rs113163670 | chr7:35725851:G:A | - | 0.0571047137626082 | 0.0423738224810814 | LUAD | Female-baised eQTL |
| rs76436621 | chr7:35726590:T:C | - | 0.0571047137626082 | 0.0423738224810814 | LUAD | Female-baised eQTL |
| rs74740875 | chr7:35732319:C:T | - | 0.0571047137626082 | 0.0423738224810814 | LUAD | Female-baised eQTL |
| rs148925451 | chr7:35738427:C:T | - | 0.0571047137626082 | 0.0423738224810814 | LUAD | Female-baised eQTL |
| rs10276755 | chr7:34640347:C:T | - | 0.0333722450497134 | 0.0429448927003807 | LUAD | Female-baised eQTL |
| rs60341215 | chr7:34641184:G:A | - | 0.0333722450497134 | 0.0429448927003807 | LUAD | Female-baised eQTL |
| rs11771123 | chr7:32013949:C:A | - | 0.0493727686642675 | 0.0430608642422588 | LUAD | Female-baised eQTL |
| rs12672706 | chr7:35796693:A:T | - | 0.0570779772212498 | 0.0430628427498181 | LUAD | Female-baised eQTL |
| rs10245758 | chr7:34622244:C:T | - | 0.0384810453634452 | 0.0438406734115213 | LUAD | Female-baised eQTL |
| rs76444535 | chr7:36214801:C:T | - | 0.0531859809772434 | 0.0448019036468865 | LUAD | Female-baised eQTL |
| rs1563687 | chr7:34651767:A:C | - | 0.0336604879089209 | 0.0450265129110719 | LUAD | Female-baised eQTL |
| rs17170539 | chr7:36221746:A:G | - | 0.0531636792297416 | 0.0450621946896218 | LUAD | Female-baised eQTL |
| rs78679401 | chr7:34501852:C:T | - | 0.0593309794957776 | 0.0451303592635787 | LUAD | Female-baised eQTL |
| rs6946048 | chr7:36197100:C:T | - | 0.0531503560739241 | 0.0451644075848218 | LUAD | Female-baised eQTL |
| rs77620582 | chr7:36206109:T:C | - | 0.0531503560739241 | 0.0451644075848218 | LUAD | Female-baised eQTL |
| rs74849143 | chr7:35802276:A:G | - | 0.0558281596160188 | 0.0471136241685393 | LUAD | Female-baised eQTL |
| rs28619339 | chr7:35353818:G:T | - | 0.0602499004333335 | 0.0474964596523485 | LUAD | Female-baised eQTL |
| rs79184762 | chr7:35780788:C:T | - | 0.0557695159046794 | 0.0475731484108643 | LUAD | Female-baised eQTL |
| rs141347135 | chr7:35789386:T:C | - | 0.0557695159046794 | 0.0475731484108643 | LUAD | Female-baised eQTL |
| rs137987849 | chr7:35642382:A:G | - | 0.060446435644559 | 0.0491684310841499 | LUAD | Female-baised eQTL |
| rs76703402 | chr7:35696145:C:T | - | 0.0603707263915956 | 0.0496053800018956 | LUAD | Female-baised eQTL |
| rs111656153 | chr7:35696911:G:A | - | 0.0603707263915956 | 0.0496053800018956 | LUAD | Female-baised eQTL |
| rs76385666 | chr7:35648773:C:G | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs4537222 | chr7:35662628:T:C | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs140983672 | chr7:35663720:T:C | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs78137801 | chr7:35671833:T:C | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs75567113 | chr7:35681097:T:C | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs144278751 | chr7:35682302:T:A | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs7778468 | chr7:35685501:T:C | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs112315113 | chr7:35686098:C:A | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
| rs17699327 | chr7:35689966:G:A | - | 0.0603554456050275 | 0.0497245112602282 | LUAD | Female-baised eQTL |
Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs67620734 | chr7:42399476:C:T | - | 0.133967594595296 | 0.0327039990692555 | GBM | Male-baised eQTL |
| rs2195891 | chr7:42399846:T:A | - | 0.133967594595296 | 0.0327039990692555 | GBM | Male-baised eQTL |
| rs6966512 | chr7:42401162:G:A | - | 0.133967594595296 | 0.0327039990692555 | GBM | Male-baised eQTL |
| rs17172054 | chr7:42406112:C:T | - | 0.133967594595296 | 0.0327039990692555 | GBM | Male-baised eQTL |
| rs11761423 | chr7:39078714:C:A | - | 0.0753546736175228 | 0.0133592352212358 | LGG | Male-baised eQTL |
| rs7777579 | chr7:37537071:G:A | - | 0.0729307265737635 | 0.000537986162930427 | KIRC | Male-baised eQTL |
| rs17171084 | chr7:37520253:C:A | - | 0.0748126012720905 | 0.000589524278027106 | KIRC | Male-baised eQTL |
| rs35086526 | chr7:37520707:G:T | - | 0.0748126012720905 | 0.000589524278027106 | KIRC | Male-baised eQTL |
| rs34499743 | chr7:37527798:A:T | - | 0.0734362921125403 | 0.000715090959883937 | KIRC | Male-baised eQTL |
| rs7781607 | chr7:37537579:C:T | - | 0.065102580499124 | 0.0013759706192971 | KIRC | Male-baised eQTL |
| rs57716044 | chr7:37532439:G:T | - | 0.0596870998725052 | 0.00702583377129191 | KIRC | Male-baised eQTL |
| rs72621241 | chr7:37524662:T:C | - | 0.0565692827459512 | 0.0074955321365254 | KIRC | Male-baised eQTL |
| rs7803098 | chr7:37526040:T:C | - | 0.0529386848080503 | 0.0127091457609378 | KIRC | Male-baised eQTL |
| rs9638881 | chr7:32512983:C:G | - | 0.0306983759294693 | 0.0152546097169087 | KIRC | Male-baised eQTL |
| rs7803425 | chr7:37526257:T:G | - | 0.0514181856454848 | 0.0173756181712902 | KIRC | Male-baised eQTL |
| rs2190516 | chr7:42338420:A:C | - | 0.0479978058346272 | 0.0291441947992206 | KIRC | Male-baised eQTL |
| rs12532964 | chr7:42339234:A:G | - | 0.0460999169814392 | 0.0427172890779012 | KIRC | Male-baised eQTL |
| rs2190515 | chr7:42338496:T:C | - | 0.0452689103054324 | 0.0437686987614567 | KIRC | Male-baised eQTL |
| rs79771939 | chr7:45903570:G:A | - | 0.0397902059311689 | 0.0454645775020045 | KIRC | Male-baised eQTL |
| rs7808664 | chr7:32877938:G:A | - | 0.0279904782598167 | 0.0486010689418183 | KIRC | Male-baised eQTL |
| rs7811609 | chr7:32890985:C:T | - | 0.0279904782598167 | 0.0486010689418183 | KIRC | Male-baised eQTL |
| rs35443929 | chr7:32895822:C:A | - | 0.0279904782598167 | 0.0486010689418183 | KIRC | Male-baised eQTL |
| rs10251577 | chr7:39035121:T:A | - | 0.0926856634516549 | 4.34030025391896e-06 | LUAD | Male-baised eQTL |
| rs10251322 | chr7:39013799:G:C | - | 0.0925932112396109 | 4.54682781053418e-06 | LUAD | Male-baised eQTL |
| rs143463575 | chr7:39026109:G:A | - | 0.0924792830331489 | 4.70474493447192e-06 | LUAD | Male-baised eQTL |
| rs10230554 | chr7:39038969:G:A | - | 0.0882157093134256 | 1.5941848561737e-05 | LUAD | Male-baised eQTL |
| rs73697925 | chr7:39039879:C:T | - | 0.0882157093134256 | 1.5941848561737e-05 | LUAD | Male-baised eQTL |
| rs10085866 | chr7:39042872:A:G | - | 0.0882157093134256 | 1.5941848561737e-05 | LUAD | Male-baised eQTL |
| rs702821 | chr7:39022700:G:C | - | -0.0585625257587592 | 0.000409429673158915 | LUAD | Male-baised eQTL |
| rs859530 | chr7:39023265:G:T | - | -0.0585625257587592 | 0.000409429673158915 | LUAD | Male-baised eQTL |
| rs859544 | chr7:39027893:A:G | - | -0.0585625257587592 | 0.000409429673158915 | LUAD | Male-baised eQTL |
| rs9886128 | chr7:39029758:A:G | - | 0.0585625257587591 | 0.000409429673158915 | LUAD | Male-baised eQTL |
| rs859548 | chr7:39019157:G:A | - | -0.0584123110282439 | 0.000438561826435037 | LUAD | Male-baised eQTL |
| rs702822 | chr7:39023103:C:G | - | -0.0584123110282439 | 0.000438561826435037 | LUAD | Male-baised eQTL |
| rs1102669 | chr7:39025749:C:G | - | -0.0584123110282439 | 0.000438561826435037 | LUAD | Male-baised eQTL |
| rs12702228 | chr7:46516283:G:C | - | 0.059801570609976 | 0.0031530475133134 | LUAD | Male-baised eQTL |
| rs10238973 | chr7:49105340:T:C | - | -0.0548099223850536 | 0.00972892225582623 | LUAD | Male-baised eQTL |
| rs6945994 | chr7:49445102:T:G | - | 0.0608216464562292 | 0.030669479495074 | LUAD | Male-baised eQTL |
| rs111446673 | chr7:49445704:C:T | - | 0.0608216464562292 | 0.030669479495074 | LUAD | Male-baised eQTL |
| rs17393459 | chr7:49453113:A:T | - | 0.0591529314654309 | 0.0360395227095513 | LUAD | Male-baised eQTL |
| rs111365656 | chr7:49515159:G:A | - | 0.0567749343834458 | 0.042924023804662 | LUAD | Male-baised eQTL |
Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg17347386 | chr7:42153376 | gene | -0.248386572673334 | 4.4285060229241e-10 | -0.42916259351924596 | 1.914942990058442e-12 | LGG |
| cg01013023 | chr7:42091525 | gene | -0.381128463906368 | 6.07990984985956e-06 | -0.31061959707555997 | 3.0229378111206857e-08 | BLCA |
Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg14396995 | chr7:42238490 | promoter | -0.284675377911022 | 9.25479486681411e-07 | -0.5941548708068137 | 6.250238572480822e-09 | PAAD |
| cg26557756 | chr7:42238497 | promoter | -0.214767728299553 | 1.02684977323101e-09 | -0.44045865969698633 | 1.7702013263432574e-13 | LUAD |
Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of GLI3 |
Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000106571 | GLI3 | C0011999 | Diastematomyelia | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0024623 | Malignant neoplasm of stomach | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0027794 | Neural Tube Defects | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0027806 | Neurenteric Cyst | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0038356 | Stomach Neoplasms | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0080218 | Tethered Cord Syndrome | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0152234 | Iniencephaly | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0152426 | Craniorachischisis | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0152427 | Polydactyly | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0162835 | Hypopigmentation disorder | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0220697 | POLYDACTYLY, POSTAXIAL | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0238198 | Gastrointestinal Stromal Tumors | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0265220 | Pallister-Hall syndrome | 2 | CTD_human |
| ENSG00000106571 | GLI3 | C0265306 | Greig cephalopolysyndactyly syndrome | 6 | CTD_human |
| ENSG00000106571 | GLI3 | C0266453 | Exencephaly | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0342418 | Hypothalamic hamartomas | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0344479 | Spinal Cord Myelodysplasia | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C0702169 | Acrania | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C1708349 | Hereditary Diffuse Gastric Cancer | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C1868111 | Polydactyly, preaxial 4 | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C1868120 | POSTAXIAL POLYDACTYLY, TYPE B | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C3179349 | Gastrointestinal Stromal Sarcoma | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C3887487 | Postaxial polydactyly type A | 1 | CTD_human |
| ENSG00000106571 | GLI3 | C4282400 | Polydactyly, Postaxial, Type A1 | 1 | CTD_human |