|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000106565 |
Summary for TMEM176B |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000106565 | Gene symbol | TMEM176B |
| Gene name | transmembrane protein 176B | |
| HGNC | 29596 | |
| Entrez ID | 28959 | |
| Gene type | protein_coding | |
| Synonyms | TMEM176B|LR8|MS4B2 | |
| UniProtAcc | Q3YBM2 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TMEM176B |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TMEM176B | 6.39e+03 | 1.04e+00 | 2.30e-01 | 4.51e+00 | 6.39e-06 | 2.01e-05 | LUAD |
| TMEM176B | 2.26e+03 | 1.39e+00 | 3.13e-01 | 4.42e+00 | 9.74e-06 | 4.41e-05 | THCA |
| TMEM176B | 3.31e+04 | 1.01e+00 | 2.13e-01 | 4.76e+00 | 1.98e-06 | 6.67e-06 | KIRP |
| TMEM176B | 2.53e+04 | -3.29e+00 | 4.60e-01 | -7.15e+00 | 8.96e-13 | 2.35e-11 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for TMEM176B |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for TMEM176B |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.37e-01 | 3.66e-01 | -2.06e+00 | 3.98e-02 | 4.59e-02 | -1.29e-01 |
| ESCA | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter,gene body | 4.55e-01 | 3.43e-01 | 2.14e+00 | 3.21e-02 | 4.47e-02 | 1.12e-01 |
| ESCA | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 5.51e-01 | 4.34e-01 | 2.12e+00 | 3.37e-02 | 4.53e-02 | 1.17e-01 |
| ESCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter,gene body | 3.61e-01 | 2.61e-01 | 2.52e+00 | 1.17e-02 | 2.91e-02 | 1.00e-01 |
| ACC | cg05726600 | chr7:150801506 | CGI:chr7:150799721-150801118 | promoter | 6.12e-01 | 7.38e-01 | -2.47e+00 | 1.35e-02 | 2.98e-02 | -1.26e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg05726600 | chr7:150801506 | CGI:chr7:150799721-150801118 | promoter | 1.60e-01 | 2.94e-01 | -5.35e+00 | 8.62e-08 | 4.40e-07 | -1.35e-01 |
| HNSC | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter | 5.90e-01 | 8.01e-01 | -4.71e+00 | 2.46e-06 | 1.20e-05 | -2.11e-01 |
| HNSC | cg21053135 | chr7:150802649 | CGI:chr7:150799721-150801118 | promoter | 6.88e-01 | 8.09e-01 | -2.57e+00 | 1.02e-02 | 1.30e-02 | -1.21e-01 |
| LUSC | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter,gene body | 4.17e-01 | 1.34e-01 | 3.53e+00 | 4.19e-04 | 1.49e-03 | 2.83e-01 |
| LUSC | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 4.66e-01 | 2.22e-01 | 3.61e+00 | 3.09e-04 | 1.24e-03 | 2.43e-01 |
| LUSC | cg26385222 | chr7:150799989 | CGI:chr7:150799721-150801118 | promoter,gene body | 4.68e-01 | 2.49e-01 | 3.59e+00 | 3.32e-04 | 1.29e-03 | 2.19e-01 |
| LUSC | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.20e-01 | 1.06e-01 | 3.26e+00 | 1.12e-03 | 2.80e-03 | 1.14e-01 |
| LUSC | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter | 6.43e-01 | 8.62e-01 | -3.14e+00 | 1.71e-03 | 3.74e-03 | -2.19e-01 |
| LUSC | cg21053135 | chr7:150802649 | CGI:chr7:150799721-150801118 | promoter | 7.24e-01 | 8.92e-01 | -2.57e+00 | 1.01e-02 | 1.40e-02 | -1.67e-01 |
| BLCA | cg04861380 | chr7:150800575 | CGI:chr7:150799721-150801118 | promoter,gene body | 1.99e-01 | 2.41e-02 | 3.11e+00 | 1.88e-03 | 3.73e-03 | 1.75e-01 |
| BLCA | cg19336959 | chr7:150800615 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.05e-01 | 3.07e-02 | 3.00e+00 | 2.66e-03 | 4.92e-03 | 1.74e-01 |
| BLCA | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter,gene body | 4.07e-01 | 2.16e-01 | 2.06e+00 | 3.92e-02 | 4.14e-02 | 1.92e-01 |
| BLCA | cg26385222 | chr7:150799989 | CGI:chr7:150799721-150801118 | promoter,gene body | 4.61e-01 | 3.13e-01 | 2.59e+00 | 9.47e-03 | 1.35e-02 | 1.48e-01 |
| BLCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter,gene body | 3.34e-01 | 1.26e-01 | 3.33e+00 | 8.61e-04 | 2.02e-03 | 2.08e-01 |
| BLCA | cg25124476 | chr7:150800650 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.53e-01 | 9.46e-02 | 2.98e+00 | 2.90e-03 | 5.27e-03 | 1.58e-01 |
| BLCA | cg00417408 | chr7:150800652 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.74e-01 | 1.14e-01 | 2.89e+00 | 3.82e-03 | 6.57e-03 | 1.61e-01 |
| BLCA | cg07769074 | chr7:150800672 | CGI:chr7:150799721-150801118 | promoter,gene body | 1.68e-01 | 5.79e-02 | 2.63e+00 | 8.49e-03 | 1.24e-02 | 1.10e-01 |
| BLCA | cg08359956 | chr7:150801117 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 3.25e-01 | 1.93e-01 | 2.18e+00 | 2.94e-02 | 3.31e-02 | 1.32e-01 |
| LIHC | cg21053135 | chr7:150802649 | CGI:chr7:150799721-150801118 | promoter | 7.69e-01 | 9.00e-01 | -3.88e+00 | 1.03e-04 | 2.12e-04 | -1.31e-01 |
| CHOL | cg08359956 | chr7:150801117 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 3.81e-01 | 1.29e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 2.52e-01 |
| CHOL | cg03964111 | chr7:150801405 | CGI:chr7:150799721-150801118 | promoter | 5.08e-01 | 2.10e-01 | 2.29e+00 | 2.23e-02 | 3.24e-02 | 2.97e-01 |
| CHOL | cg10409299 | chr7:150801755 | CGI:chr7:150799721-150801118 | promoter | 7.43e-01 | 5.04e-01 | 3.10e+00 | 1.96e-03 | 1.07e-02 | 2.40e-01 |
| CHOL | cg07208344 | chr7:150802274 | CGI:chr7:150799721-150801118 | promoter | 8.51e-01 | 6.09e-01 | 3.54e+00 | 4.02e-04 | 8.32e-03 | 2.42e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg04861380 | chr7:150800575 | CGI:chr7:150799721-150801118 | promoter,gene body | 1.51e-01 | 2.28e-02 | 9.05e+00 | 1.48e-19 | 7.69e-19 | 1.29e-01 |
| BRCA | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.87e-01 | 9.07e-02 | 8.44e+00 | 3.14e-17 | 1.36e-16 | 1.96e-01 |
| BRCA | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 4.01e-01 | 1.86e-01 | 8.77e+00 | 1.85e-18 | 8.80e-18 | 2.15e-01 |
| BRCA | cg26385222 | chr7:150799989 | CGI:chr7:150799721-150801118 | promoter,gene body | 3.55e-01 | 2.04e-01 | 7.62e+00 | 2.59e-14 | 8.95e-14 | 1.52e-01 |
| BRCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.37e-01 | 1.05e-01 | 6.93e+00 | 4.36e-12 | 1.27e-11 | 1.32e-01 |
| BRCA | cg25124476 | chr7:150800650 | CGI:chr7:150799721-150801118 | promoter,gene body | 1.99e-01 | 8.56e-02 | 6.46e+00 | 1.04e-10 | 2.72e-10 | 1.13e-01 |
| BRCA | cg00417408 | chr7:150800652 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.14e-01 | 9.44e-02 | 7.02e+00 | 2.26e-12 | 6.74e-12 | 1.20e-01 |
| BRCA | cg08359956 | chr7:150801117 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 4.09e-01 | 3.04e-01 | 6.01e+00 | 1.84e-09 | 4.37e-09 | 1.05e-01 |
| BRCA | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter | 7.66e-01 | 9.16e-01 | -8.93e+00 | 4.30e-19 | 2.16e-18 | -1.50e-01 |
| BRCA | cg21053135 | chr7:150802649 | CGI:chr7:150799721-150801118 | promoter | 8.08e-01 | 9.31e-01 | -8.45e+00 | 2.90e-17 | 1.26e-16 | -1.23e-01 |
| LUAD | cg19336959 | chr7:150800615 | CGI:chr7:150799721-150801118 | promoter,gene body | 1.28e-01 | 2.49e-02 | 3.36e+00 | 7.93e-04 | 2.75e-03 | 1.03e-01 |
| LUAD | cg00417408 | chr7:150800652 | CGI:chr7:150799721-150801118 | promoter,gene body | 2.02e-01 | 8.64e-02 | 3.11e+00 | 1.90e-03 | 4.92e-03 | 1.15e-01 |
| LIHC | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter | 6.06e-01 | 4.88e-01 | 2.10e+00 | 3.61e-02 | 3.86e-02 | 1.17e-01 |
| KIRP | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 2.04e-01 | 6.44e-02 | 2.87e+00 | 4.17e-03 | 9.48e-03 | 1.40e-01 |
Top |
Exon skipping events with PSI in TCGA for TMEM176B |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for TMEM176B |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for TMEM176B |
| TFs related to TMEM176B. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PCPG | PLAGL2 | TMEM176B | 3.52e+00 | 9.58e-03 | 4.33e+00 | 9.82e-01 | Female-biased |
| TMEM176B related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for TMEM176B |
| RBPs related to ES in TMEM176B. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| TMEM176B related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs56147424 | chr7:155243636:C:A | - | 0.175089330045587 | 0.0392573550288782 | LUSC | Female-baised eQTL |
| rs79787537 | chr7:155247419:C:T | - | 0.174042950815313 | 0.0418017725766898 | LUSC | Female-baised eQTL |
| rs55686460 | chr7:155243739:C:T | - | 0.174153169271714 | 0.0418266136499648 | LUSC | Female-baised eQTL |
| rs10272702 | chr7:143261090:T:C | - | 0.236022275019276 | 0.000290428356662926 | BLCA | Female-baised eQTL |
| rs77689119 | chr7:155898541:A:G | - | 0.253682566619342 | 0.0148213482743805 | BLCA | Female-baised eQTL |
| rs79567485 | chr7:155893852:C:A | - | 0.253420368476465 | 0.0152353792235511 | BLCA | Female-baised eQTL |
| rs74454984 | chr7:155901136:C:A | - | 0.252167271181929 | 0.0159381625581147 | BLCA | Female-baised eQTL |
| rs140991464 | chr7:155902087:C:T | - | 0.252167271181929 | 0.0159381625581147 | BLCA | Female-baised eQTL |
| rs55639312 | chr7:155903662:G:T | - | 0.252167271181929 | 0.0159381625581147 | BLCA | Female-baised eQTL |
| rs74765187 | chr7:155904568:A:T | - | 0.252167271181929 | 0.0159381625581147 | BLCA | Female-baised eQTL |
| rs116131242 | chr7:147943620:T:G | - | 0.290070115148848 | 0.0179023820366417 | BLCA | Female-baised eQTL |
| rs79051424 | chr7:147945441:C:T | - | 0.290070115148848 | 0.0179023820366417 | BLCA | Female-baised eQTL |
| rs114515860 | chr7:147946074:G:A | - | 0.290070115148848 | 0.0179023820366417 | BLCA | Female-baised eQTL |
| rs117609483 | chr7:147945736:A:T | - | 0.267897999356917 | 0.0307199083989436 | BLCA | Female-baised eQTL |
| rs10952550 | chr7:143400947:A:G | - | -0.251391682951663 | 0.0417708079550148 | BLCA | Female-baised eQTL |
| rs6948526 | chr7:143319902:T:A | - | 0.133507255178939 | 0.0490785245849631 | BLCA | Female-baised eQTL |
| rs12538999 | chr7:156883660:C:G | - | 0.0793214225966156 | 0.0159205951174467 | LUAD | Female-baised eQTL |
| rs73167961 | chr7:156886153:A:G | - | 0.0793214225966156 | 0.0159205951174467 | LUAD | Female-baised eQTL |
| rs12539560 | chr7:156889806:C:T | - | 0.0793214225966156 | 0.0159205951174467 | LUAD | Female-baised eQTL |
| rs34291908 | chr7:156848194:T:C | - | 0.0758608724090854 | 0.020944150062428 | LUAD | Female-baised eQTL |
| rs73167908 | chr7:156848910:G:A | - | 0.0758608724090854 | 0.020944150062428 | LUAD | Female-baised eQTL |
| rs11763829 | chr7:156850723:T:C | - | 0.0758608724090854 | 0.020944150062428 | LUAD | Female-baised eQTL |
| rs11766294 | chr7:156851100:G:A | - | 0.0758608724090854 | 0.020944150062428 | LUAD | Female-baised eQTL |
| rs12531061 | chr7:156780108:G:A | - | 0.0789886315369894 | 0.0227170688834959 | LUAD | Female-baised eQTL |
| rs62478411 | chr7:151952403:C:T | - | 0.0798407560351808 | 0.0242401999693693 | LUAD | Female-baised eQTL |
| rs12535212 | chr7:156849044:A:G | - | 0.0689770111537795 | 0.0398051091118635 | LUAD | Female-baised eQTL |
| rs183263721 | chr7:156892719:C:G | - | 0.0731552171653035 | 0.0494905734694066 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11981103 | chr7:141272843:C:T | - | 0.0529793994357212 | 0.027749756913031 | COAD | Male-baised eQTL |
| rs917157 | chr7:141274731:T:C | - | 0.0502580412656475 | 0.0403356608904005 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000106565 |
| CpG Site: cg10409299 | |
| Position to Gene: promoter | |
| Male Effect: -0.332239357707762 | |
| Female Effect: - | |
 | Gene ID: ENSG00000106565 |
| CpG Site: cg05385923 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.399716015483684 | |
 | Gene ID: ENSG00000106565 |
| CpG Site: cg10409299 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.39960041605997 | |
 | Gene ID: ENSG00000106565 |
| CpG Site: cg05726600 | |
| Position to Gene: promoter | |
| Male Effect: -0.275688353218157 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10409299 | chr7:150801755 | promoter | -0.332239357707762 | 6.50476351924228e-08 | -0.5828618697311629 | 3.0379227462413796e-10 | PAAD |
| cg05726600 | chr7:150801506 | promoter | -0.275688353218157 | 4.28684242137857e-13 | -0.4374047246589224 | 6.184930880525317e-15 | LGG |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg05385923 | chr7:150798793 | gene | -0.399716015483684 | 7.5136115926661e-08 | -0.3962749408576614 | 5.573778208102075e-11 | LUAD |
| cg10409299 | chr7:150801755 | promoter | -0.39960041605997 | 7.58862508455032e-08 | -0.3959738983865756 | 5.297680271841859e-11 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of TMEM176B |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
