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Gene: ENSG00000105953 |
Summary for OGDH |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000105953 | Gene symbol | OGDH |
| Gene name | oxoglutarate dehydrogenase | |
| HGNC | 8124 | |
| Entrez ID | 4967 | |
| Gene type | protein_coding | |
| Synonyms | OGDH|E1k|OGDC-E1|OGDH2|KGD1 | |
| UniProtAcc | Q02218 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for OGDH |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for OGDH |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for OGDH |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg07408740 | chr7:44605707 | CGI:chr7:44606466-44607224 | promoter | 3.94e-01 | 5.16e-01 | -3.99e+00 | 6.47e-05 | 1.80e-04 | -1.22e-01 |
| LUSC | cg07408740 | chr7:44605707 | CGI:chr7:44606466-44607224 | promoter | 3.39e-01 | 5.03e-01 | -3.64e+00 | 2.72e-04 | 1.15e-03 | -1.65e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg07408740 | chr7:44605707 | CGI:chr7:44606466-44607224 | promoter | 3.27e-01 | 4.92e-01 | -1.13e+01 | 9.40e-30 | 1.33e-28 | -1.65e-01 |
Top |
Exon skipping events with PSI in TCGA for OGDH |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for OGDH |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| STAD | OGDH-201 | chr7_44625912_+ | 5.88e-01 | 3.77e-01 | 2.79e+00 | 5.28e-03 | 4.96e-02 | 2.11e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| KIRC | OGDH-201 | chr7_44625152_+ | 7.89e-01 | 9.15e-01 | -2.33e+00 | 1.98e-02 | 2.81e-02 | -1.26e-01 |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for OGDH |
| TFs related to OGDH. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| MESO | FOXR2 | OGDH | 3.95e+00 | 9.82e-01 | 2.29e+00 | 1.96e-03 | Male-biased |
| MESO | ZNF418 | OGDH | 4.53e+00 | 9.94e-01 | 2.31e+00 | 2.79e-04 | Male-biased |
| MESO | ZNF879 | OGDH | 4.21e+00 | 9.88e-01 | 2.50e+00 | 1.73e-03 | Male-biased |
| PCPG | ZNF418 | OGDH | 4.19e+00 | 9.80e-01 | 3.33e+00 | 7.81e-03 | Male-biased |
| SARC | ZNF235 | OGDH | 4.00e+00 | 9.82e-01 | 3.11e+00 | 1.38e-03 | Male-biased |
| SARC | ZNF287 | OGDH | 4.03e+00 | 9.82e-01 | 3.21e+00 | 2.01e-03 | Male-biased |
| SARC | ZNF418 | OGDH | 4.08e+00 | 9.82e-01 | 3.33e+00 | 3.19e-03 | Male-biased |
| THYM | ZNF418 | OGDH | 2.28e+00 | 2.08e-04 | 3.93e+00 | 9.81e-01 | Female-biased |
| OGDH related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for OGDH |
| RBPs related to ES in OGDH. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | PCBP2 | exon_skip_465789 | 6.88e+00 | 9.80e-01 | 6.35e+00 | 4.60e-03 | Male-biased |
| ACC | RBM3 | exon_skip_465772 | 1.35e+01 | 9.94e-01 | 1.30e+01 | 5.25e-03 | Male-biased |
| UVM | FMR1 | exon_skip_465780 | 8.59e+00 | 9.83e-01 | 8.29e+00 | 1.04e-02 | Male-biased |
| UVM | NCL | exon_skip_465792 | 8.02e+00 | 9.84e-01 | 7.69e+00 | 7.16e-03 | Male-biased |
| THYM | SAMD4A | exon_skip_465788 | 6.57e+00 | 9.81e-01 | 6.07e+00 | 1.55e-03 | Male-biased |
| LIHC | SAMD4A | exon_skip_465782 | 7.00e+00 | 9.84e-01 | 6.38e+00 | 1.79e-03 | Male-biased |
| LUSC | FMR1 | exon_skip_465780 | 8.13e+00 | 4.91e-03 | 8.56e+00 | 9.89e-01 | Female-biased |
| COAD | SAMD4A | exon_skip_465788 | 6.63e+00 | 9.83e-01 | 6.00e+00 | 6.79e-04 | Male-biased |
| COAD | SAMD4A | exon_skip_465792 | 7.52e+00 | 9.90e-01 | 6.70e+00 | 1.73e-04 | Male-biased |
| DLBC | FMR1 | exon_skip_465794 | 8.57e+00 | 9.83e-01 | 8.24e+00 | 1.10e-02 | Male-biased |
| LUAD | FMR1 | exon_skip_465780 | 8.22e+00 | 2.30e-03 | 8.70e+00 | 9.92e-01 | Female-biased |
| CHOL | FMR1 | exon_skip_465794 | 8.69e+00 | 9.88e-01 | 8.23e+00 | 6.47e-03 | Male-biased |
| CHOL | RBM3 | exon_skip_465772 | 1.42e+01 | 9.98e-01 | 1.35e+01 | 1.60e-03 | Male-biased |
| CHOL | SAMD4A | exon_skip_465788 | 6.58e+00 | 4.01e-03 | 7.11e+00 | 9.83e-01 | Female-biased |
| ESCA | SAMD4A | exon_skip_465792 | 7.45e+00 | 9.89e-01 | 6.61e+00 | 8.21e-04 | Male-biased |
| READ | FMR1 | exon_skip_465794 | 8.76e+00 | 9.89e-01 | 8.39e+00 | 6.07e-03 | Male-biased |
| READ | SAMD4A | exon_skip_465782 | 6.77e+00 | 9.84e-01 | 6.19e+00 | 8.76e-04 | Male-biased |
| MESO | NCL | exon_skip_465792 | 7.68e+00 | 9.59e-03 | 8.04e+00 | 9.82e-01 | Female-biased |
| MESO | QKI | exon_skip_465755 | 1.51e+01 | 1.33e-03 | 1.57e+01 | 9.99e-01 | Female-biased |
| MESO | RBM3 | exon_skip_465772 | 1.37e+01 | 6.14e-04 | 1.44e+01 | 9.99e-01 | Female-biased |
| MESO | SAMD4A | exon_skip_465788 | 6.02e+00 | 1.07e-03 | 6.60e+00 | 9.81e-01 | Female-biased |
| KIRC | SAMD4A | exon_skip_465792 | 6.55e+00 | 7.09e-04 | 7.14e+00 | 9.87e-01 | Female-biased |
| KICH | NCL | exon_skip_465792 | 7.67e+00 | 3.86e-03 | 8.08e+00 | 9.88e-01 | Female-biased |
| KICH | SRSF9 | exon_skip_465789 | 6.30e+00 | 3.33e-03 | 6.72e+00 | 9.81e-01 | Female-biased |
| SKCM | NCL | exon_skip_465792 | 7.64e+00 | 5.14e-03 | 8.07e+00 | 9.87e-01 | Female-biased |
| SKCM | SAMD4A | exon_skip_465782 | 6.28e+00 | 3.25e-04 | 7.06e+00 | 9.86e-01 | Female-biased |
| SARC | FMR1 | exon_skip_465794 | 8.39e+00 | 1.18e-02 | 8.74e+00 | 9.83e-01 | Female-biased |
| SARC | RBM3 | exon_skip_465772 | 1.37e+01 | 1.69e-02 | 1.40e+01 | 9.83e-01 | Female-biased |
| SARC | SAMD4A | exon_skip_465788 | 6.72e+00 | 9.83e-01 | 6.01e+00 | 6.15e-04 | Male-biased |
| OGDH related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs117795103 | chr7:38332250:C:T | - | 0.179678450103082 | 0.0192274681105072 | LIHC | Female-baised eQTL |
| rs79360624 | chr7:38324927:T:C | - | 0.17657230092797 | 0.0251635900761296 | LIHC | Female-baised eQTL |
| rs117896266 | chr7:38325011:C:T | - | 0.17657230092797 | 0.0251635900761296 | LIHC | Female-baised eQTL |
| rs76477775 | chr7:38326356:T:C | - | 0.175967390628195 | 0.0269060685012813 | LIHC | Female-baised eQTL |
| rs76706499 | chr7:38326895:G:A | - | 0.175967390628195 | 0.0269060685012813 | LIHC | Female-baised eQTL |
| rs76884168 | chr7:38725091:T:C | - | 0.199983615741091 | 0.00259531425526975 | LUSC | Female-baised eQTL |
| rs117225157 | chr7:38816972:C:G | - | 0.185886874291011 | 0.00594558639017114 | LUSC | Female-baised eQTL |
| rs76137055 | chr7:38823010:T:C | - | 0.185886874291011 | 0.00594558639017114 | LUSC | Female-baised eQTL |
| rs117511477 | chr7:38937614:C:T | - | 0.152663453223727 | 0.0372106260752514 | LUSC | Female-baised eQTL |
| rs113596213 | chr7:41851944:G:A | - | 0.182124435503931 | 0.0453247436529991 | LUSC | Female-baised eQTL |
| rs28890598 | chr7:41840741:C:T | - | 0.132606133406073 | 0.00215623986058461 | KIRC | Female-baised eQTL |
| rs58024826 | chr7:45121592:C:T | - | 0.151125023223564 | 0.0251127255748879 | KIRC | Female-baised eQTL |
| rs56378175 | chr7:38321480:A:G | - | 0.116010025511102 | 0.0310502654999259 | KIRC | Female-baised eQTL |
| rs62452869 | chr7:40937737:C:T | - | 0.0892935070569845 | 0.0159473789482186 | LUAD | Female-baised eQTL |
| rs1319235 | chr7:49395965:G:A | - | -0.0528837677370967 | 0.0369510565944271 | LUAD | Female-baised eQTL |
| rs78534704 | chr7:51154641:G:A | - | -0.144183554489986 | 0.00745285615226218 | COAD | Female-baised eQTL |
| rs80187465 | chr7:51137151:C:T | - | -0.146385579468601 | 0.00860161090417331 | COAD | Female-baised eQTL |
| rs76969049 | chr7:51141710:T:G | - | -0.146385579468601 | 0.00860161090417331 | COAD | Female-baised eQTL |
| rs74616763 | chr7:51287103:G:A | - | -0.111249156971118 | 0.0206241806167345 | COAD | Female-baised eQTL |
| rs57379398 | chr7:51265238:G:A | - | -0.111038969207623 | 0.0229845093366662 | COAD | Female-baised eQTL |
| rs73316839 | chr7:51142167:G:A | - | -0.130441931067668 | 0.0298375428405427 | COAD | Female-baised eQTL |
| rs73330635 | chr7:51281220:T:C | - | -0.0992188834193927 | 0.0389800761007995 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs75078181 | chr7:52084963:A:T | - | 0.225366921725065 | 1.47797460277012e-05 | THCA | Male-baised eQTL |
| rs78161943 | chr7:52044802:G:A | - | 0.204286629924855 | 0.000157106602618661 | THCA | Male-baised eQTL |
| rs7798707 | chr7:52045840:A:G | - | 0.204286629924855 | 0.000157106602618661 | THCA | Male-baised eQTL |
| rs79423617 | chr7:52046596:T:A | - | 0.204286629924855 | 0.000157106602618661 | THCA | Male-baised eQTL |
| rs76779311 | chr7:52047201:C:T | - | 0.204286629924855 | 0.000157106602618661 | THCA | Male-baised eQTL |
| rs111909498 | chr7:52049477:T:G | - | 0.204286629924855 | 0.000157106602618661 | THCA | Male-baised eQTL |
| rs7790851 | chr7:52050045:T:C | - | 0.204286629924855 | 0.000157106602618661 | THCA | Male-baised eQTL |
| rs75743233 | chr7:52080448:T:C | - | 0.200640752964201 | 0.00029856895866952 | THCA | Male-baised eQTL |
| rs76155324 | chr7:52089750:C:T | - | 0.200640752964201 | 0.00029856895866952 | THCA | Male-baised eQTL |
| rs6942886 | chr7:52072048:T:G | - | 0.18732748231094 | 0.0008441144815992 | THCA | Male-baised eQTL |
| rs77437260 | chr7:52052025:G:A | - | 0.186297529489693 | 0.000997767491275868 | THCA | Male-baised eQTL |
| rs78493025 | chr7:52054594:G:T | - | 0.186297529489693 | 0.000997767491275868 | THCA | Male-baised eQTL |
| rs79217815 | chr7:52057411:C:A | - | 0.186297529489693 | 0.000997767491275868 | THCA | Male-baised eQTL |
| rs75360233 | chr7:52064992:A:G | - | 0.186297529489693 | 0.000997767491275868 | THCA | Male-baised eQTL |
| rs75046138 | chr7:52070318:A:T | - | 0.186297529489693 | 0.000997767491275868 | THCA | Male-baised eQTL |
| rs9649748 | chr7:52024880:C:T | - | 0.218082734382977 | 0.0292761280134295 | THCA | Male-baised eQTL |
| rs736763 | chr7:41017164:G:A | - | 0.135369584141264 | 0.012019306944001 | LUAD | Male-baised eQTL |
| rs7810451 | chr7:41018147:C:G | - | 0.135369584141264 | 0.012019306944001 | LUAD | Male-baised eQTL |
| rs1962786 | chr7:41019062:T:A | - | 0.135369584141264 | 0.012019306944001 | LUAD | Male-baised eQTL |
| rs7803955 | chr7:41016360:A:G | - | 0.134352110676256 | 0.013523380229965 | LUAD | Male-baised eQTL |
| rs188657 | chr7:44558427:A:G | - | 0.0760019631041769 | 0.0016899504054039 | COAD | Male-baised eQTL |
| rs217391 | chr7:44556955:T:G | - | 0.075959221206237 | 0.00178171071347928 | COAD | Male-baised eQTL |
| rs217388 | chr7:44559869:A:G | - | 0.0754947089582809 | 0.00195758039110279 | COAD | Male-baised eQTL |
| rs217394 | chr7:44556313:G:A | - | 0.0757610218660222 | 0.00218003175582018 | COAD | Male-baised eQTL |
| rs217397 | chr7:44554050:T:C | - | 0.0755769698400302 | 0.00241340918460581 | COAD | Male-baised eQTL |
| rs2268307 | chr7:44629860:G:A | gene | -0.0740509101346749 | 0.00260636793172634 | COAD | Male-baised eQTL |
| rs3757565 | chr7:44631792:T:G | gene | -0.0740509101346749 | 0.00260636793172634 | COAD | Male-baised eQTL |
| rs217383 | chr7:44564475:C:G | - | 0.074157801102866 | 0.0026404401059994 | COAD | Male-baised eQTL |
| rs28536594 | chr7:44605487:C:T | promoter | -0.0741095358818023 | 0.00266922533768246 | COAD | Male-baised eQTL |
| rs56000965 | chr7:44613756:A:G | gene | -0.0741095358818023 | 0.00266922533768246 | COAD | Male-baised eQTL |
| rs217356 | chr7:44586064:A:G | - | 0.0741095358818023 | 0.00266922533768246 | COAD | Male-baised eQTL |
| rs1859509 | chr7:44631130:A:T | gene | -0.0735578053836351 | 0.00300846952532822 | COAD | Male-baised eQTL |
| rs3757566 | chr7:44631901:A:G | gene | -0.0735578053836351 | 0.00300846952532822 | COAD | Male-baised eQTL |
| rs3801398 | chr7:44633563:C:T | gene | -0.0735578053836351 | 0.00300846952532822 | COAD | Male-baised eQTL |
| rs3801399 | chr7:44633712:G:A | gene | -0.0735578053836351 | 0.00300846952532822 | COAD | Male-baised eQTL |
| rs217384 | chr7:44564418:T:G | - | 0.0736473603961784 | 0.00305919798849193 | COAD | Male-baised eQTL |
| rs6656 | chr7:44566499:C:T | - | 0.0736473603961784 | 0.00305919798849193 | COAD | Male-baised eQTL |
| rs217380 | chr7:44566740:C:T | - | 0.0736473603961784 | 0.00305919798849193 | COAD | Male-baised eQTL |
| rs11770011 | chr7:44591533:G:A | - | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs10239322 | chr7:44604546:G:C | - | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs56270255 | chr7:44606873:C:T | gene,promoter | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs56141231 | chr7:44613028:G:A | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs7458549 | chr7:44614974:G:A | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs2331137 | chr7:44615058:G:T | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs2331138 | chr7:44615159:G:T | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs28690923 | chr7:44616548:T:C | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs11767009 | chr7:44618565:C:G | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs28866305 | chr7:44619884:T:C | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs28589910 | chr7:44620170:A:G | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs55904633 | chr7:44621280:C:T | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs6949541 | chr7:44623239:G:A | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs2268302 | chr7:44625997:C:T | gene | -0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs217353 | chr7:44588608:C:T | - | 0.0736166329811195 | 0.00308083247994579 | COAD | Male-baised eQTL |
| rs217352 | chr7:44588866:G:A | - | 0.0726741729663491 | 0.00380471222725336 | COAD | Male-baised eQTL |
| rs217364 | chr7:44577555:T:C | - | 0.0721221299580851 | 0.00404341391265133 | COAD | Male-baised eQTL |
| rs217361 | chr7:44579703:T:C | - | 0.0714576617617673 | 0.00446006377208609 | COAD | Male-baised eQTL |
| rs217357 | chr7:44583317:T:C | - | 0.0714545511640229 | 0.00448234944768716 | COAD | Male-baised eQTL |
| rs217377 | chr7:44570253:C:T | - | 0.0707084566416706 | 0.00508480786647763 | COAD | Male-baised eQTL |
| rs217362 | chr7:44579000:T:A | - | 0.0707084566416706 | 0.00508480786647763 | COAD | Male-baised eQTL |
| rs773393 | chr7:40004683:A:G | - | 0.0648339467313341 | 0.00568418464243776 | COAD | Male-baised eQTL |
| rs1812036 | chr7:44627837:T:C | gene | -0.0714040878205862 | 0.00595589976024587 | COAD | Male-baised eQTL |
| rs217367 | chr7:44576389:A:T | - | 0.0687965700469001 | 0.00614539115139957 | COAD | Male-baised eQTL |
| rs217360 | chr7:44580763:G:A | - | 0.0691043560504448 | 0.00706784530685483 | COAD | Male-baised eQTL |
| rs8580 | chr7:44581237:C:A | - | 0.0691043560504448 | 0.00706784530685483 | COAD | Male-baised eQTL |
| rs9690188 | chr7:40150803:T:C | - | -0.0650267365775622 | 0.00928194507777065 | COAD | Male-baised eQTL |
| rs1874233 | chr7:40157346:C:T | - | -0.0650267365775622 | 0.00928194507777065 | COAD | Male-baised eQTL |
| rs11763047 | chr7:40161368:C:A | - | -0.0650267365775622 | 0.00928194507777065 | COAD | Male-baised eQTL |
| rs2024200 | chr7:40154661:T:G | - | -0.064913671056964 | 0.00951090618096042 | COAD | Male-baised eQTL |
| rs2268305 | chr7:44629697:A:G | gene | -0.0683909184485564 | 0.00995030362554935 | COAD | Male-baised eQTL |
| rs740093 | chr7:44630065:G:A | gene | -0.0683909184485564 | 0.00995030362554935 | COAD | Male-baised eQTL |
| rs740094 | chr7:44630099:G:A | gene | -0.0683909184485564 | 0.00995030362554935 | COAD | Male-baised eQTL |
| rs6974493 | chr7:40143079:C:T | - | -0.0637133180195127 | 0.0101396120755304 | COAD | Male-baised eQTL |
| rs217374 | chr7:44572748:G:C | - | 0.0662944842794619 | 0.0101571692718459 | COAD | Male-baised eQTL |
| rs10272641 | chr7:40050333:C:G | - | -0.0614546482946692 | 0.0120173853089418 | COAD | Male-baised eQTL |
| rs773402 | chr7:40033478:A:C | - | 0.0609346985673909 | 0.0152579192250375 | COAD | Male-baised eQTL |
| rs17587111 | chr7:46756921:A:G | - | 0.0858140998811389 | 0.0161034531851716 | COAD | Male-baised eQTL |
| rs28444842 | chr7:44591435:C:T | - | -0.0655578019861062 | 0.0161952903958852 | COAD | Male-baised eQTL |
| rs11765589 | chr7:44611951:G:A | gene | -0.0652169325021496 | 0.0175046403717794 | COAD | Male-baised eQTL |
| rs2107768 | chr7:44614498:T:C | gene | -0.0652169325021496 | 0.0175046403717794 | COAD | Male-baised eQTL |
| rs56206842 | chr7:44615540:A:G | gene | -0.0652169325021496 | 0.0175046403717794 | COAD | Male-baised eQTL |
| rs17133537 | chr7:44618141:T:C | gene | -0.0652169325021496 | 0.0175046403717794 | COAD | Male-baised eQTL |
| rs11768323 | chr7:37587813:A:C | - | 0.0642937383783025 | 0.0183836645272746 | COAD | Male-baised eQTL |
| rs10245434 | chr7:44624171:A:G | gene | -0.064439887140062 | 0.0197857207467599 | COAD | Male-baised eQTL |
| rs773410 | chr7:40017937:T:A | - | 0.0592838717784061 | 0.020149565136832 | COAD | Male-baised eQTL |
| rs1522878 | chr7:40045601:A:T | - | -0.060284760135432 | 0.0203342393270077 | COAD | Male-baised eQTL |
| rs773397 | chr7:40000537:T:C | - | 0.0590852696342559 | 0.0210377454353492 | COAD | Male-baised eQTL |
| rs6971483 | chr7:44614312:G:T | gene | -0.0643389528627969 | 0.0223412362730555 | COAD | Male-baised eQTL |
| rs2009560 | chr7:40176084:C:T | - | -0.0598269701346499 | 0.0262330636592927 | COAD | Male-baised eQTL |
| rs12333929 | chr7:40200440:A:G | - | -0.0598269701346499 | 0.0262330636592927 | COAD | Male-baised eQTL |
| rs6968402 | chr7:40206703:A:G | - | -0.0598269701346499 | 0.0262330636592927 | COAD | Male-baised eQTL |
| rs4407779 | chr7:44590083:C:G | - | -0.06377788051842 | 0.0266360993328904 | COAD | Male-baised eQTL |
| rs217372 | chr7:44573154:T:C | - | 0.0612327306714871 | 0.0320215818806533 | COAD | Male-baised eQTL |
| rs4723589 | chr7:36897237:A:G | - | -0.088464906442119 | 0.0329371432869221 | COAD | Male-baised eQTL |
| rs4723596 | chr7:36911439:T:C | - | -0.0880281711503448 | 0.0338335878607995 | COAD | Male-baised eQTL |
| rs979491 | chr7:37627268:T:G | - | 0.0587247866545912 | 0.034431759886274 | COAD | Male-baised eQTL |
| rs4723679 | chr7:37600435:C:T | - | 0.0604507774217482 | 0.0356840256539775 | COAD | Male-baised eQTL |
| rs4723688 | chr7:37637732:C:T | - | 0.0602546290935232 | 0.0362132656446017 | COAD | Male-baised eQTL |
| rs6952993 | chr7:37626270:A:C | - | 0.05822074464055 | 0.0365981374299531 | COAD | Male-baised eQTL |
| rs217389 | chr7:44559607:A:G | - | 0.0596731399030837 | 0.0386011385211167 | COAD | Male-baised eQTL |
| rs886651 | chr7:44630555:T:C | gene | -0.0583050926339523 | 0.0396142552226009 | COAD | Male-baised eQTL |
| rs1597434 | chr7:37628558:T:G | - | 0.0577680341564648 | 0.0399877815618994 | COAD | Male-baised eQTL |
| rs10276163 | chr7:37645068:C:T | - | 0.0577058585000696 | 0.0403686726564503 | COAD | Male-baised eQTL |
| rs6462781 | chr7:37636225:T:C | - | 0.0578629096217124 | 0.0407143186300155 | COAD | Male-baised eQTL |
| rs115484079 | chr7:37636902:G:C | - | 0.0575053427741458 | 0.0415273787209303 | COAD | Male-baised eQTL |
| rs1375964 | chr7:37628261:T:C | - | 0.0571952058562814 | 0.0421791130030699 | COAD | Male-baised eQTL |
| rs10262889 | chr7:37632373:T:C | - | 0.0571952058562814 | 0.0421791130030699 | COAD | Male-baised eQTL |
| rs2122447 | chr7:37641711:C:T | - | 0.0571355261493844 | 0.0425651897238868 | COAD | Male-baised eQTL |
| rs4723689 | chr7:37643238:T:C | - | 0.0571355261493844 | 0.0425651897238868 | COAD | Male-baised eQTL |
| rs33999222 | chr7:40041054:A:G | - | -0.0553297180650654 | 0.0427539805135 | COAD | Male-baised eQTL |
| rs10275761 | chr7:40033683:A:G | - | -0.0553922956052577 | 0.0432551415428194 | COAD | Male-baised eQTL |
| rs10246466 | chr7:40033742:C:T | - | -0.0553922956052577 | 0.0432551415428194 | COAD | Male-baised eQTL |
| rs6966917 | chr7:40035862:G:A | - | -0.0553922956052577 | 0.0432551415428194 | COAD | Male-baised eQTL |
| rs10271787 | chr7:37643755:G:A | - | 0.0585889686900663 | 0.0440579432483963 | COAD | Male-baised eQTL |
| rs6462780 | chr7:37635969:A:C | - | 0.0560967113958077 | 0.0472878656509914 | COAD | Male-baised eQTL |
| rs10240043 | chr7:37571045:C:G | - | 0.0559845832011541 | 0.0475601995334874 | COAD | Male-baised eQTL |
| rs773381 | chr7:39984801:C:T | - | 0.0541002606681295 | 0.048127324273659 | COAD | Male-baised eQTL |
| rs1257699 | chr7:39988473:G:A | - | 0.0541002606681295 | 0.048127324273659 | COAD | Male-baised eQTL |
| rs10236039 | chr7:37630159:G:A | - | 0.0566334475006279 | 0.0481864515295737 | COAD | Male-baised eQTL |
| rs10247545 | chr7:37632350:G:A | - | 0.0566334475006279 | 0.0481864515295737 | COAD | Male-baised eQTL |
| rs28872599 | chr7:37634829:G:T | - | 0.0566334475006279 | 0.0481864515295737 | COAD | Male-baised eQTL |
| rs773413 | chr7:40015483:A:G | - | 0.0539712119506693 | 0.0482695421284526 | COAD | Male-baised eQTL |
| rs6956126 | chr7:46750864:T:G | - | -0.0928528919055235 | 0.0491839825384545 | COAD | Male-baised eQTL |
| rs3906962 | chr7:37676905:A:G | - | 0.0587281056157535 | 0.0497928020804259 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of OGDH |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000105953 | OGDH | C0019193 | Hepatitis, Toxic | 1 | CTD_human |
| ENSG00000105953 | OGDH | C0860207 | Drug-Induced Liver Disease | 1 | CTD_human |
| ENSG00000105953 | OGDH | C1262760 | Hepatitis, Drug-Induced | 1 | CTD_human |
| ENSG00000105953 | OGDH | C2752074 | ALPHA-KETOGLUTARATE DEHYDROGENASE DEFICIENCY | 1 | CTD_human |
| ENSG00000105953 | OGDH | C3658290 | Drug-Induced Acute Liver Injury | 1 | CTD_human |
| ENSG00000105953 | OGDH | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
| ENSG00000105953 | OGDH | C4279912 | Chemically-Induced Liver Toxicity | 1 | CTD_human |
