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Gene: ENSG00000104763 |
Summary for ASAH1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000104763 | Gene symbol | ASAH1 |
| Gene name | N-acylsphingosine amidohydrolase 1 | |
| HGNC | 735 | |
| Entrez ID | 427 | |
| Gene type | protein_coding | |
| Synonyms | ASAH1|AC|PHP32|FLJ21558|ACDase | |
| UniProtAcc | Q13510 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ASAH1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ASAH1 | 4.99e+03 | -1.23e+00 | 1.11e-01 | -1.11e+01 | 1.36e-28 | 7.19e-27 | HNSC |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for ASAH1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for ASAH1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg12052340 | chr8:18086481 | CGI:chr8:18083790-18084950 | promoter | 4.90e-01 | 3.61e-01 | 2.31e+00 | 2.07e-02 | 3.54e-02 | 1.29e-01 |
| ESCA | cg04912297 | chr8:18085784 | CGI:chr8:18083790-18084950 | promoter | 4.63e-01 | 5.73e-01 | -3.68e+00 | 2.30e-04 | 1.18e-03 | -1.10e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| ESCA | cg04912297 | chr8:18085784 | CGI:chr8:18083790-18084950 | promoter | 5.73e-01 | 4.08e-01 | 2.96e+00 | 3.09e-03 | 3.38e-02 | 1.65e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg04912297 | chr8:18085784 | CGI:chr8:18083790-18084950 | promoter | 5.50e-01 | 4.01e-01 | 9.91e+00 | 3.90e-23 | 2.78e-22 | 1.49e-01 |
| BRCA | cg12052340 | chr8:18086481 | CGI:chr8:18083790-18084950 | promoter | 4.90e-01 | 7.06e-01 | -1.00e+01 | 1.26e-23 | 9.37e-23 | -2.16e-01 |
| HNSC | cg12052340 | chr8:18086481 | CGI:chr8:18083790-18084950 | promoter | 5.83e-01 | 3.76e-01 | 2.33e+00 | 1.98e-02 | 2.74e-02 | 2.07e-01 |
| KIRP | cg18929511 | chr8:18085484 | CGI:chr8:18083790-18084950 | promoter | 3.16e-01 | 1.91e-01 | 2.36e+00 | 1.83e-02 | 2.52e-02 | 1.24e-01 |
Top |
Exon skipping events with PSI in TCGA for ASAH1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for ASAH1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for ASAH1 |
| TFs related to ASAH1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ASAH1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ASAH1 |
| RBPs related to ES in ASAH1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ASAH1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000104763 | LINC01197,hsa-mir-873,ASAH1 | Male-specific ceRNA | TCGA-HNSC |
| ENSG00000104763 | LINC01344,hsa-mir-873,ASAH1 | Male-specific ceRNA | TCGA-HNSC |
| ENSG00000104763 | PCBP1-AS1,hsa-mir-873,ASAH1 | Male-specific ceRNA | TCGA-HNSC |
| ENSG00000104763 | AF111167.2,hsa-mir-873,ASAH1 | Male-specific ceRNA | TCGA-HNSC |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs4872206 | chr8:23930226:G:A | - | 0.278724407037237 | 0.0482772156656208 | GBM | Female-baised eQTL |
| rs2672228 | chr8:19255907:C:T | - | 0.110075436955992 | 0.00238045701091497 | SARC | Female-baised eQTL |
| rs3789015 | chr8:16185204:T:C | - | 0.0810467992980593 | 0.0122585163547907 | SARC | Female-baised eQTL |
| rs75017967 | chr8:16183413:A:C | - | 0.0797100771720961 | 0.0136251961200598 | SARC | Female-baised eQTL |
| rs9632859 | chr8:23694787:G:A | - | 0.0771738666328354 | 0.0168018221166838 | SARC | Female-baised eQTL |
| rs9632860 | chr8:23694788:A:T | - | 0.0771738666328354 | 0.0168018221166838 | SARC | Female-baised eQTL |
| rs351559 | chr8:16142691:C:T | - | 0.0708518690175778 | 0.0245957162153873 | SARC | Female-baised eQTL |
| rs9632857 | chr8:23694684:T:A | - | 0.073211078739217 | 0.0256157763505624 | SARC | Female-baised eQTL |
| rs9632858 | chr8:23694741:G:A | - | 0.073211078739217 | 0.0256157763505624 | SARC | Female-baised eQTL |
| rs9632855 | chr8:23694316:G:C | - | 0.071036566366176 | 0.0360308098150178 | SARC | Female-baised eQTL |
| rs13279832 | chr8:13534019:A:G | - | -0.284482408138273 | 0.000277509838523329 | KIRP | Female-baised eQTL |
| rs75140902 | chr8:13476072:C:T | - | 0.28380202641576 | 0.00028044940956528 | KIRP | Female-baised eQTL |
| rs79694253 | chr8:13461819:G:A | - | 0.282439453785352 | 0.000335138382009068 | KIRP | Female-baised eQTL |
| rs77079215 | chr8:13463890:A:C | - | 0.282439453785352 | 0.000335138382009068 | KIRP | Female-baised eQTL |
| rs2634458 | chr8:18600936:G:C | - | 0.257157388106872 | 0.00919322634995433 | KIRP | Female-baised eQTL |
| rs6992157 | chr8:20538719:G:C | - | 0.134617877155116 | 0.0106283782190703 | KIRP | Female-baised eQTL |
| rs7459487 | chr8:9520712:A:G | - | -0.280312711053629 | 0.0145065314035225 | KIRP | Female-baised eQTL |
| rs17089142 | chr8:23346440:C:T | - | 0.128731193611593 | 0.0166012103373999 | KIRP | Female-baised eQTL |
| rs67393975 | chr8:20538101:G:A | - | 0.121216910040628 | 0.0213345836635986 | KIRP | Female-baised eQTL |
| rs7846631 | chr8:23350002:G:A | - | 0.129464986753371 | 0.0244571525426863 | KIRP | Female-baised eQTL |
| rs34658243 | chr8:23350382:C:A | - | 0.129464986753371 | 0.0244571525426863 | KIRP | Female-baised eQTL |
| rs2285273 | chr8:17310364:A:C | - | 0.127843099034876 | 0.0253770849260992 | KIRP | Female-baised eQTL |
| rs11993011 | chr8:20538606:G:T | - | 0.123626013324644 | 0.0257150448062271 | KIRP | Female-baised eQTL |
| rs4872108 | chr8:23352598:T:C | - | 0.119385673113924 | 0.0317406102539999 | KIRP | Female-baised eQTL |
| rs7845726 | chr8:23353103:A:G | - | 0.119385673113924 | 0.0317406102539999 | KIRP | Female-baised eQTL |
| rs60859503 | chr8:23353267:G:A | - | 0.119385673113924 | 0.0317406102539999 | KIRP | Female-baised eQTL |
| rs1471523 | chr8:20537180:A:G | - | 0.114064296213971 | 0.0318638926956964 | KIRP | Female-baised eQTL |
| rs73211761 | chr8:18597083:C:A | - | 0.15603988077357 | 0.0229131739367303 | LIHC | Female-baised eQTL |
| rs1506894 | chr8:19051895:G:C | - | 0.147831163823082 | 0.0492975168449168 | LUSC | Female-baised eQTL |
| rs11249977 | chr8:10220793:G:A | - | 0.0969943360096665 | 0.0113886514902791 | STAD | Female-baised eQTL |
| rs12546027 | chr8:10221262:G:A | - | 0.0969943360096665 | 0.0113886514902791 | STAD | Female-baised eQTL |
| rs12541192 | chr8:10221387:C:A | - | 0.0969943360096665 | 0.0113886514902791 | STAD | Female-baised eQTL |
| rs10903338 | chr8:11452781:T:C | - | -0.102331060099183 | 0.022571336519981 | STAD | Female-baised eQTL |
| rs2409766 | chr8:11446277:A:C | - | -0.0990372500512758 | 0.0356350650180987 | STAD | Female-baised eQTL |
| rs4840561 | chr8:11448951:G:A | - | -0.0982559516297831 | 0.0406016516673828 | STAD | Female-baised eQTL |
| rs12543841 | chr8:10221343:A:G | - | 0.0847053153101275 | 0.0474609537623958 | STAD | Female-baised eQTL |
| rs11997467 | chr8:17347769:A:G | - | 0.0813287260188877 | 0.00294581932716635 | KIRC | Female-baised eQTL |
| rs7011504 | chr8:17351024:T:C | - | 0.0689311079157704 | 0.00387129830484571 | KIRC | Female-baised eQTL |
| rs146002600 | chr8:9790552:T:C | - | 0.0819371626140949 | 0.00438497064349549 | KIRC | Female-baised eQTL |
| rs10099016 | chr8:16402103:A:G | - | -0.0824628509214187 | 0.00555737818356895 | KIRC | Female-baised eQTL |
| rs10106217 | chr8:23328021:C:T | - | 0.10315082377745 | 0.0100081637835508 | KIRC | Female-baised eQTL |
| rs7829031 | chr8:28030205:G:C | - | -0.0717917159431806 | 0.0285766574562603 | KIRC | Female-baised eQTL |
| rs1389376 | chr8:16956946:A:T | - | -0.071023749261282 | 0.039910814140472 | KIRC | Female-baised eQTL |
| rs17057783 | chr8:27757704:T:G | - | 0.131495771604545 | 0.0399187625127959 | KIRC | Female-baised eQTL |
| rs117200464 | chr8:19046399:G:A | - | 0.215126903911636 | 0.000694233567697105 | BLCA | Female-baised eQTL |
| rs79218278 | chr8:19010212:G:C | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs76928113 | chr8:19010591:G:A | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs77644639 | chr8:19015694:T:G | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs77845633 | chr8:19016910:G:A | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs79236153 | chr8:19016911:C:A | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs80038167 | chr8:19017426:C:A | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs75213539 | chr8:19018175:T:G | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs74884604 | chr8:19019087:G:A | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs79708709 | chr8:19019995:C:G | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs60820465 | chr8:19020826:C:T | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs77108577 | chr8:19022163:A:G | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs80231667 | chr8:19023260:T:G | - | 0.189152448463962 | 0.00176450683722848 | BLCA | Female-baised eQTL |
| rs57243659 | chr8:19026498:T:C | - | 0.188795088663457 | 0.00187882018740171 | BLCA | Female-baised eQTL |
| rs79971821 | chr8:19040256:G:A | - | 0.193560323927245 | 0.00314253082224144 | BLCA | Female-baised eQTL |
| rs56768160 | chr8:19042524:T:A | - | 0.193560323927245 | 0.00314253082224144 | BLCA | Female-baised eQTL |
| rs61203870 | chr8:19042533:T:G | - | 0.193560323927245 | 0.00314253082224144 | BLCA | Female-baised eQTL |
| rs17384956 | chr8:19043247:G:C | - | 0.193560323927245 | 0.00314253082224144 | BLCA | Female-baised eQTL |
| rs17469510 | chr8:19044739:A:C | - | 0.193560323927245 | 0.00314253082224144 | BLCA | Female-baised eQTL |
| rs143508562 | chr8:19013600:G:A | - | 0.180747747667515 | 0.00353468885307492 | BLCA | Female-baised eQTL |
| rs76589725 | chr8:19035337:C:T | - | 0.186274277896607 | 0.00356495047563881 | BLCA | Female-baised eQTL |
| rs142243235 | chr8:19036030:C:A | - | 0.186274277896607 | 0.00356495047563881 | BLCA | Female-baised eQTL |
| rs118159240 | chr8:19046140:C:G | - | 0.191043698891098 | 0.00411129814099866 | BLCA | Female-baised eQTL |
| rs78477377 | chr8:19028840:T:C | - | 0.18420849305003 | 0.00444739454137659 | BLCA | Female-baised eQTL |
| rs118160463 | chr8:18998415:C:T | - | 0.172075276868448 | 0.00667290843608424 | BLCA | Female-baised eQTL |
| rs113544301 | chr8:18998498:T:C | - | 0.172075276868448 | 0.00667290843608424 | BLCA | Female-baised eQTL |
| rs76608793 | chr8:18999019:T:C | - | 0.172075276868448 | 0.00667290843608424 | BLCA | Female-baised eQTL |
| rs74474376 | chr8:18999244:C:T | - | 0.171975921239348 | 0.00674755728717339 | BLCA | Female-baised eQTL |
| rs76050997 | chr8:19002563:A:G | - | 0.171969942057675 | 0.006752495344991 | BLCA | Female-baised eQTL |
| rs74394967 | chr8:19002791:T:G | - | 0.171969942057675 | 0.006752495344991 | BLCA | Female-baised eQTL |
| rs77591078 | chr8:19003646:G:A | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs76113926 | chr8:19003708:C:T | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs80130293 | chr8:19003806:G:A | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs74973554 | chr8:19003848:G:T | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs79514962 | chr8:19003897:G:A | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs79221754 | chr8:19003907:G:A | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs78718162 | chr8:19004052:G:A | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs79590259 | chr8:19004199:C:T | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs78662987 | chr8:19004369:C:T | - | 0.171407062473112 | 0.00741158856146281 | BLCA | Female-baised eQTL |
| rs78275431 | chr8:19012229:T:C | - | 0.153027625985663 | 0.018969857411712 | BLCA | Female-baised eQTL |
| rs75007198 | chr8:19007253:A:G | - | 0.153230184574754 | 0.0191951868346332 | BLCA | Female-baised eQTL |
| rs73596652 | chr8:19031955:T:C | - | 0.160236531468035 | 0.022525422985459 | BLCA | Female-baised eQTL |
| rs73594686 | chr8:19029782:A:G | - | 0.159892070020869 | 0.0228986676754616 | BLCA | Female-baised eQTL |
| rs74304231 | chr8:19003174:A:G | - | 0.142235607453397 | 0.0331816143270193 | BLCA | Female-baised eQTL |
| rs78316270 | chr8:19003276:G:C | - | 0.141091693823646 | 0.0372737776988156 | BLCA | Female-baised eQTL |
| rs75458706 | chr8:19002957:G:C | - | 0.140440763544606 | 0.044531054749904 | BLCA | Female-baised eQTL |
| rs10102937 | chr8:19003973:T:C | - | 0.140088078072488 | 0.0471982055592408 | BLCA | Female-baised eQTL |
| rs4579570 | chr8:19069467:A:C | - | 0.0509125345422445 | 0.0366007888385906 | LUAD | Female-baised eQTL |
| rs34747927 | chr8:19065341:C:T | - | -0.0517918153629749 | 0.0425474891028434 | LUAD | Female-baised eQTL |
| rs4339648 | chr8:24736375:G:A | - | 0.0502758242180996 | 0.0444049559377591 | LUAD | Female-baised eQTL |
| rs4921623 | chr8:19065591:G:A | - | -0.0510091015512729 | 0.0497658563181402 | LUAD | Female-baised eQTL |
| rs4469501 | chr8:11967447:C:T | - | -0.0803360714350853 | 0.0298721226837519 | COAD | Female-baised eQTL |
| rs2945230 | chr8:8252414:A:G | - | 0.0684061853081636 | 0.0329087471654006 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs60860936 | chr8:13202014:C:T | - | 0.185897892587406 | 0.0212912435879951 | GBM | Male-baised eQTL |
| rs6983639 | chr8:10440278:A:G | - | 0.224689477595013 | 0.0488639398816648 | GBM | Male-baised eQTL |
| rs6985140 | chr8:9679917:A:G | - | 0.194896286076945 | 0.00177853437397853 | THCA | Male-baised eQTL |
| rs4529464 | chr8:9708056:A:G | - | 0.187527307646528 | 0.00352519175204041 | THCA | Male-baised eQTL |
| rs6981763 | chr8:9690769:T:G | - | 0.187160164028583 | 0.00371061678147172 | THCA | Male-baised eQTL |
| rs12056794 | chr8:9696405:A:G | - | 0.185859803056803 | 0.00429839016459693 | THCA | Male-baised eQTL |
| rs4841215 | chr8:9780798:C:T | - | 0.208593006684785 | 0.00544574597978136 | THCA | Male-baised eQTL |
| rs77956414 | chr8:9734226:C:A | - | 0.220249761865009 | 0.00612218546761476 | THCA | Male-baised eQTL |
| rs6987746 | chr8:9742743:T:G | - | 0.220249761865009 | 0.00612218546761476 | THCA | Male-baised eQTL |
| rs60857446 | chr8:9748682:C:A | - | 0.220249761865009 | 0.00612218546761476 | THCA | Male-baised eQTL |
| rs76491219 | chr8:9736380:T:C | - | 0.214602306377399 | 0.00676361863431205 | THCA | Male-baised eQTL |
| rs77548287 | chr8:9745019:A:G | - | 0.214602306377399 | 0.00676361863431205 | THCA | Male-baised eQTL |
| rs12234999 | chr8:9746067:G:A | - | 0.214602306377399 | 0.00676361863431205 | THCA | Male-baised eQTL |
| rs12235001 | chr8:9746105:G:A | - | 0.214602306377399 | 0.00676361863431205 | THCA | Male-baised eQTL |
| rs7018348 | chr8:9587694:G:A | - | 0.224281954720279 | 0.00686510422381474 | THCA | Male-baised eQTL |
| rs202242670 | chr8:9738855:G:T | - | 0.214061832334247 | 0.00733367360294715 | THCA | Male-baised eQTL |
| rs200489642 | chr8:9739348:C:T | - | 0.214061832334247 | 0.00733367360294715 | THCA | Male-baised eQTL |
| rs200209786 | chr8:9739826:A:G | - | 0.214061832334247 | 0.00733367360294715 | THCA | Male-baised eQTL |
| rs77403801 | chr8:9724217:C:T | - | 0.213497959393032 | 0.00781341354634417 | THCA | Male-baised eQTL |
| rs142765729 | chr8:9731384:C:T | - | 0.213497959393032 | 0.00781341354634417 | THCA | Male-baised eQTL |
| rs7846023 | chr8:9736414:T:C | - | 0.209012002295924 | 0.00790720698366715 | THCA | Male-baised eQTL |
| rs77341338 | chr8:9710431:C:T | - | 0.208471002507528 | 0.00822630879332338 | THCA | Male-baised eQTL |
| rs117410020 | chr8:9729902:G:A | - | 0.208471002507528 | 0.00822630879332338 | THCA | Male-baised eQTL |
| rs74301631 | chr8:9758468:G:A | - | 0.210188635422129 | 0.0111975562690476 | THCA | Male-baised eQTL |
| rs35052906 | chr8:9710190:C:A | - | 0.19813449175628 | 0.0162310987133925 | THCA | Male-baised eQTL |
| rs146228171 | chr8:9762862:G:C | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs73662516 | chr8:9763872:A:G | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs6987259 | chr8:9764598:C:T | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs6986755 | chr8:9765049:G:A | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs114760225 | chr8:9767677:C:T | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs75256485 | chr8:9769548:G:A | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs35420737 | chr8:9770281:A:G | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs76972663 | chr8:9770569:G:C | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs60801852 | chr8:9770848:A:C | - | 0.201058291168802 | 0.0187276988546271 | THCA | Male-baised eQTL |
| rs74891397 | chr8:9782516:G:C | - | 0.184259034771379 | 0.0192880067386323 | THCA | Male-baised eQTL |
| rs11785739 | chr8:9782890:C:A | - | 0.184259034771379 | 0.0192880067386323 | THCA | Male-baised eQTL |
| rs7014218 | chr8:9719844:T:C | - | 0.195254656549751 | 0.0217820611286526 | THCA | Male-baised eQTL |
| rs7827395 | chr8:9757042:T:C | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs79298615 | chr8:9757486:C:G | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs11991831 | chr8:9758512:A:G | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs11988208 | chr8:9758693:C:T | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs11995167 | chr8:9758870:G:A | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs28495967 | chr8:9759682:A:C | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs6995292 | chr8:9761284:C:T | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs7813518 | chr8:9762031:A:G | - | 0.199373850140031 | 0.0217858763700087 | THCA | Male-baised eQTL |
| rs7837923 | chr8:9585640:C:T | - | 0.191654278598739 | 0.0227995717003801 | THCA | Male-baised eQTL |
| rs3209608 | chr8:9773655:C:G | - | 0.197415336494141 | 0.0264580287072992 | THCA | Male-baised eQTL |
| rs33944167 | chr8:9706975:G:A | - | 0.189759848932392 | 0.0275273051233693 | THCA | Male-baised eQTL |
| rs34614689 | chr8:9747987:C:A | - | 0.183297361047688 | 0.0277454083047729 | THCA | Male-baised eQTL |
| rs78635875 | chr8:9707801:A:G | - | 0.186351600983433 | 0.0278669473249649 | THCA | Male-baised eQTL |
| rs60222666 | chr8:9708678:T:C | - | 0.186351600983433 | 0.0278669473249649 | THCA | Male-baised eQTL |
| rs74208434 | chr8:9567765:T:C | - | 0.187859628489078 | 0.0322675163190705 | THCA | Male-baised eQTL |
| rs78598051 | chr8:9570377:A:G | - | 0.187859628489078 | 0.0322675163190705 | THCA | Male-baised eQTL |
| rs79523048 | chr8:9573428:C:A | - | 0.187859628489078 | 0.0322675163190705 | THCA | Male-baised eQTL |
| rs191501874 | chr8:9658568:A:G | - | 0.187000452189438 | 0.035223366009584 | THCA | Male-baised eQTL |
| rs78943150 | chr8:9663811:G:A | - | 0.187000452189438 | 0.035223366009584 | THCA | Male-baised eQTL |
| rs77128001 | chr8:9562037:G:C | - | 0.18774729690131 | 0.0433960747243965 | THCA | Male-baised eQTL |
| rs200442818 | chr8:23314163:A:G | - | 0.0465948007191248 | 0.0273650048989447 | LIHC | Male-baised eQTL |
| rs192930749 | chr8:23314694:G:C | - | 0.0465948007191248 | 0.0273650048989447 | LIHC | Male-baised eQTL |
| rs12544014 | chr8:23314906:G:A | - | 0.0465948007191248 | 0.0273650048989447 | LIHC | Male-baised eQTL |
| rs57679053 | chr8:23316150:G:A | - | 0.0466322792347901 | 0.0273709663112566 | LIHC | Male-baised eQTL |
| rs61676020 | chr8:23316714:C:T | - | 0.0470177347436496 | 0.0275364405251568 | LIHC | Male-baised eQTL |
| rs201292175 | chr8:23314322:T:C | - | 0.0452673896314216 | 0.0343702708085879 | LIHC | Male-baised eQTL |
| rs17089055 | chr8:23310341:G:C | - | 0.040101888152613 | 0.044087900502021 | LIHC | Male-baised eQTL |
| rs2294126 | chr8:23309922:T:C | - | 0.0396937322332656 | 0.0464021398561657 | LIHC | Male-baised eQTL |
| rs62494464 | chr8:19576271:G:A | - | 0.0435953963482638 | 0.0477643791457223 | LIHC | Male-baised eQTL |
| rs2736269 | chr8:11331807:G:C | - | -0.0459262431863272 | 0.0285276086803257 | STAD | Male-baised eQTL |
| rs185977 | chr8:13399217:C:A | - | -0.0425646000043789 | 0.00544250572620969 | KIRC | Male-baised eQTL |
| rs289578 | chr8:13399581:G:A | - | -0.0425646000043789 | 0.00544250572620969 | KIRC | Male-baised eQTL |
| rs289574 | chr8:13398828:G:T | - | -0.0420444941143069 | 0.00652550795773155 | KIRC | Male-baised eQTL |
| rs289581 | chr8:13400426:A:G | - | -0.041829158791391 | 0.00741295615328851 | KIRC | Male-baised eQTL |
| rs289573 | chr8:13398634:C:G | - | -0.0404645225685554 | 0.0114429970510666 | KIRC | Male-baised eQTL |
| rs167044 | chr8:13402529:T:C | - | -0.0393377601049524 | 0.018419386399375 | KIRC | Male-baised eQTL |
| rs289585 | chr8:13403027:C:T | - | -0.0365847801516975 | 0.0235781630699706 | KIRC | Male-baised eQTL |
| rs289567 | chr8:13396095:T:C | - | -0.0384675644284673 | 0.0249630462483657 | KIRC | Male-baised eQTL |
| rs289568 | chr8:13396337:A:G | - | -0.0383991467141988 | 0.0265440940195174 | KIRC | Male-baised eQTL |
| rs7835853 | chr8:26804729:C:T | - | 0.110256777886194 | 6.00907873118053e-05 | COAD | Male-baised eQTL |
| rs13264212 | chr8:11452340:T:C | - | 0.0883098990883284 | 0.000495839600520044 | COAD | Male-baised eQTL |
| rs289626 | chr8:13441214:T:G | - | 0.165380993535439 | 0.000932241339269576 | COAD | Male-baised eQTL |
| rs289621 | chr8:13437299:A:G | - | 0.146956432817182 | 0.00390694222338223 | COAD | Male-baised eQTL |
| rs9969455 | chr8:12759646:A:G | - | 0.0750994628842341 | 0.00576518694835386 | COAD | Male-baised eQTL |
| rs4922064 | chr8:19577523:C:T | - | 0.0692287054878294 | 0.00663078399070945 | COAD | Male-baised eQTL |
| rs1814160 | chr8:19051305:C:G | - | 0.0682316618174197 | 0.00703351191243023 | COAD | Male-baised eQTL |
| rs16859 | chr8:26166275:G:A | - | 0.0679453553666643 | 0.0082608494430544 | COAD | Male-baised eQTL |
| rs28401733 | chr8:26764149:C:A | - | 0.0709590186022664 | 0.00917486838823721 | COAD | Male-baised eQTL |
| rs28722655 | chr8:26764272:C:A | - | 0.0709590186022664 | 0.00917486838823721 | COAD | Male-baised eQTL |
| rs17820804 | chr8:26123075:G:A | - | -0.111279131428293 | 0.00927935902966897 | COAD | Male-baised eQTL |
| rs78674229 | chr8:19577567:A:C | - | 0.0660765851529656 | 0.0121100794721729 | COAD | Male-baised eQTL |
| rs1563917 | chr8:21227900:A:G | - | 0.134805617938196 | 0.0124587409919843 | COAD | Male-baised eQTL |
| rs62492168 | chr8:26763004:A:G | - | 0.0694967004738667 | 0.0127169438033188 | COAD | Male-baised eQTL |
| rs1506896 | chr8:19078840:C:T | - | 0.0721019081358367 | 0.0128561839921679 | COAD | Male-baised eQTL |
| rs10112557 | chr8:8907340:A:G | - | -0.0944114110800542 | 0.0141112690113616 | COAD | Male-baised eQTL |
| rs10097779 | chr8:8907655:G:A | - | -0.0944114110800542 | 0.0141112690113616 | COAD | Male-baised eQTL |
| rs2461020 | chr8:16790674:A:T | - | 0.0645278295099076 | 0.0150077120266121 | COAD | Male-baised eQTL |
| rs10503502 | chr8:14571778:C:T | - | 0.0647257467068131 | 0.0177719146791082 | COAD | Male-baised eQTL |
| rs3779660 | chr8:11835060:G:T | - | 0.0679825071367345 | 0.0177970093510423 | COAD | Male-baised eQTL |
| rs16860 | chr8:26166390:T:G | - | 0.0648142856353198 | 0.0200505807382738 | COAD | Male-baised eQTL |
| rs1293320 | chr8:11834430:T:G | - | -0.0687764081807429 | 0.0208936295672812 | COAD | Male-baised eQTL |
| rs13263825 | chr8:9611920:A:G | - | 0.12062638735176 | 0.0216224159142898 | COAD | Male-baised eQTL |
| rs28635848 | chr8:8906444:T:G | - | -0.091248325294334 | 0.0221775446648694 | COAD | Male-baised eQTL |
| rs28373943 | chr8:8906609:A:G | - | -0.091248325294334 | 0.0221775446648694 | COAD | Male-baised eQTL |
| rs10110649 | chr8:8905568:G:A | - | -0.0906568529200046 | 0.0226664172927355 | COAD | Male-baised eQTL |
| rs28579663 | chr8:8906683:C:T | - | -0.0907041708166533 | 0.0239136229172252 | COAD | Male-baised eQTL |
| rs28445736 | chr8:8906932:G:A | - | -0.0907041708166533 | 0.0239136229172252 | COAD | Male-baised eQTL |
| rs10097305 | chr8:8907314:G:A | - | -0.0907041708166533 | 0.0239136229172252 | COAD | Male-baised eQTL |
| rs4872116 | chr8:23370186:A:G | - | -0.0636212339828579 | 0.025110180764208 | COAD | Male-baised eQTL |
| rs73192366 | chr8:14586974:T:A | - | 0.0975012363070945 | 0.0274011220396351 | COAD | Male-baised eQTL |
| rs4922145 | chr8:20272868:G:T | - | 0.147286829559189 | 0.030504683947676 | COAD | Male-baised eQTL |
| rs7824647 | chr8:14831219:G:T | - | -0.124411194464287 | 0.0330348728170735 | COAD | Male-baised eQTL |
| rs28438668 | chr8:8906468:T:G | - | -0.0880286139456093 | 0.0340544603783607 | COAD | Male-baised eQTL |
| rs4841601 | chr8:11842221:T:C | - | 0.0636133111069135 | 0.0348958144623216 | COAD | Male-baised eQTL |
| rs10866831 | chr8:23611411:A:T | - | -0.0652838157127164 | 0.0352185646991177 | COAD | Male-baised eQTL |
| rs34638238 | chr8:9638856:C:G | - | 0.112580779920638 | 0.0362637502310978 | COAD | Male-baised eQTL |
| rs7814623 | chr8:24807588:C:T | - | -0.0764512185086152 | 0.0388225114663155 | COAD | Male-baised eQTL |
| rs13256939 | chr8:9556992:C:G | - | 0.100529842570246 | 0.0396058269740519 | COAD | Male-baised eQTL |
| rs10866841 | chr8:24812096:T:C | - | -0.0735167036278779 | 0.0430327910725751 | COAD | Male-baised eQTL |
| rs2976340 | chr8:26168144:A:T | - | 0.0580545529512126 | 0.0462524154347932 | COAD | Male-baised eQTL |
| rs7822977 | chr8:24731996:C:T | - | 0.0618216141740011 | 0.0472329661593868 | COAD | Male-baised eQTL |
| rs10102186 | chr8:26767134:G:A | - | 0.0636059522744317 | 0.0473395041880735 | COAD | Male-baised eQTL |
| rs4415334 | chr8:19578725:C:T | - | 0.06046258907873 | 0.0495217779374806 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000104763 |
| CpG Site: cg04912297 | |
| Position to Gene: promoter | |
| Male Effect: -0.39871345695922 | |
| Female Effect: - | |
 | Gene ID: ENSG00000104763 |
| CpG Site: cg18067069 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.40554224273775 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg04912297 | chr8:18085784 | promoter | -0.39871345695922 | 7.49924670952839e-05 | -0.320858369489328 | 9.853668917731295e-07 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg18067069 | chr8:18080222 | gene | -0.40554224273775 | 4.89537448698361e-08 | -0.5637956058920377 | 1.42554557284021e-10 | STAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of ASAH1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000104763 | ASAH1 | C0004238 | Atrial Fibrillation | 2 | CTD_human |
| ENSG00000104763 | ASAH1 | C0023794 | Lipoidosis | 2 | CTD_human |
| ENSG00000104763 | ASAH1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| ENSG00000104763 | ASAH1 | C0036341 | Schizophrenia | 1 | PSYGENET |
| ENSG00000104763 | ASAH1 | C0221765 | Chronic schizophrenia | 1 | PSYGENET |
| ENSG00000104763 | ASAH1 | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
| ENSG00000104763 | ASAH1 | C0268255 | Farber Lipogranulomatosis | 1 | CTD_human |
| ENSG00000104763 | ASAH1 | C1834569 | Jankovic Rivera syndrome | 1 | CTD_human |
| ENSG00000104763 | ASAH1 | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
| ENSG00000104763 | ASAH1 | C3468561 | familial atrial fibrillation | 2 | CTD_human |
