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Gene: ENSG00000104381 |
Summary for GDAP1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000104381 | Gene symbol | GDAP1 |
| Gene name | ganglioside induced differentiation associated protein 1 | |
| HGNC | 15968 | |
| Entrez ID | 54332 | |
| Gene type | protein_coding | |
| Synonyms | GDAP1|CMT4|CMT2K | |
| UniProtAcc | Q8TB36 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for GDAP1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| GDAP1 | 2.35e+02 | 1.09e+00 | 2.43e-01 | 4.49e+00 | 7.20e-06 | 2.96e-05 | LIHC |
| GDAP1 | 9.77e+02 | 1.19e+00 | 3.62e-01 | 3.28e+00 | 1.04e-03 | 6.42e-03 | ESCA |
| GDAP1 | 2.07e+02 | 1.04e+00 | 3.24e-01 | 3.21e+00 | 1.31e-03 | 4.28e-03 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for GDAP1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for GDAP1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg00295293 | chr8:74322380 | CGI:chr8:74320414-74321866 | promoter,gene body | 4.87e-01 | 2.47e-01 | 2.52e+00 | 1.19e-02 | 2.85e-02 | 2.40e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg00295293 | chr8:74322380 | CGI:chr8:74320414-74321866 | promoter,gene body | 5.02e-01 | 6.38e-01 | -2.43e+00 | 1.49e-02 | 1.86e-02 | -1.36e-01 |
| COAD | cg00295293 | chr8:74322380 | CGI:chr8:74320414-74321866 | promoter,gene body | 4.51e-01 | 5.96e-01 | -2.86e+00 | 4.23e-03 | 7.22e-03 | -1.45e-01 |
| LIHC | cg00295293 | chr8:74322380 | CGI:chr8:74320414-74321866 | promoter,gene body | 6.47e-01 | 8.61e-01 | -3.11e+00 | 1.84e-03 | 2.72e-03 | -2.14e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg00295293 | chr8:74322380 | CGI:chr8:74320414-74321866 | promoter,gene body | 4.87e-01 | 8.36e-01 | -1.17e+01 | 1.17e-31 | 2.10e-30 | -3.49e-01 |
| THCA | cg00295293 | chr8:74322380 | CGI:chr8:74320414-74321866 | promoter,gene body | 3.76e-01 | 5.12e-01 | -4.19e+00 | 2.81e-05 | 1.07e-04 | -1.37e-01 |
Top |
Exon skipping events with PSI in TCGA for GDAP1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for GDAP1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for GDAP1 |
| TFs related to GDAP1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | FOXD2 | GDAP1 | 2.92e+00 | 5.91e-03 | 3.97e+00 | 9.81e-01 | Female-biased |
| CHOL | POU4F1 | GDAP1 | 3.05e+00 | 6.35e-03 | 4.09e+00 | 9.83e-01 | Female-biased |
| CHOL | POU5F1B | GDAP1 | 3.03e+00 | 6.76e-03 | 4.05e+00 | 9.82e-01 | Female-biased |
| CHOL | POU6F2 | GDAP1 | 3.37e+00 | 1.06e-02 | 4.28e+00 | 9.81e-01 | Female-biased |
| CHOL | SOX9 | GDAP1 | 3.00e+00 | 6.48e-03 | 4.03e+00 | 9.81e-01 | Female-biased |
| ESCA | BHLHE22 | GDAP1 | 4.37e+00 | 9.84e-01 | 3.64e+00 | 9.21e-03 | Male-biased |
| ESCA | IRX3 | GDAP1 | 4.11e+00 | 9.81e-01 | 3.37e+00 | 8.99e-03 | Male-biased |
| ESCA | OLIG1 | GDAP1 | 4.45e+00 | 9.80e-01 | 3.78e+00 | 1.38e-02 | Male-biased |
| PCPG | FOXD3 | GDAP1 | 4.17e+00 | 9.81e-01 | 3.31e+00 | 7.40e-03 | Male-biased |
| PCPG | FOXL1 | GDAP1 | 4.14e+00 | 9.81e-01 | 3.24e+00 | 6.30e-03 | Male-biased |
| PCPG | FOXR2 | GDAP1 | 4.23e+00 | 9.83e-01 | 3.33e+00 | 6.38e-03 | Male-biased |
| PCPG | NKX6-1 | GDAP1 | 4.24e+00 | 9.83e-01 | 3.32e+00 | 5.74e-03 | Male-biased |
| PCPG | POU3F3 | GDAP1 | 4.35e+00 | 9.85e-01 | 3.43e+00 | 5.93e-03 | Male-biased |
| PCPG | ZNF334 | GDAP1 | 4.21e+00 | 9.85e-01 | 3.20e+00 | 3.92e-03 | Male-biased |
| PCPG | ZNF418 | GDAP1 | 4.43e+00 | 9.92e-01 | 2.82e+00 | 1.81e-04 | Male-biased |
| GDAP1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for GDAP1 |
| RBPs related to ES in GDAP1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| GDAP1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000104381 | AC100814.1,hsa-mir-373,GDAP1 | Male-specific ceRNA | TCGA-LIHC |
| ENSG00000104381 | AL731563.3,hsa-mir-499a,GDAP1 | Male-specific ceRNA | TCGA-LIHC |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1563029 | chr8:77272681:G:A | - | -0.138953474062663 | 0.0275835769259079 | HNSC | Female-baised eQTL |
| rs61163252 | chr8:81524453:T:A | - | 0.352424866088266 | 0.0169256537462572 | GBM | Female-baised eQTL |
| rs76215190 | chr8:73625227:G:A | - | 0.0910320303542787 | 0.0288908638983241 | KIRC | Female-baised eQTL |
| rs7828758 | chr8:73633116:A:T | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs34220413 | chr8:73633926:C:T | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs79224194 | chr8:73634468:T:C | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs6990798 | chr8:73636784:A:G | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs56722815 | chr8:73637420:C:G | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs16938709 | chr8:73638143:G:A | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs1546325 | chr8:73641367:T:C | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs60962770 | chr8:73642224:A:G | - | 0.0901035868768497 | 0.0306207931135395 | KIRC | Female-baised eQTL |
| rs73689020 | chr8:73674703:T:A | - | 0.0905645476754861 | 0.0309290314234057 | KIRC | Female-baised eQTL |
| rs117033166 | chr8:73627206:G:A | - | 0.0893687408266043 | 0.0326373535529684 | KIRC | Female-baised eQTL |
| rs7817465 | chr8:73636042:C:A | - | 0.090102240302127 | 0.0339533129668441 | KIRC | Female-baised eQTL |
| rs60380511 | chr8:73634269:A:T | - | 0.0896792964401906 | 0.0342441571576772 | KIRC | Female-baised eQTL |
| rs7000169 | chr8:73620914:C:A | - | 0.0889638836470503 | 0.0367930948918254 | KIRC | Female-baised eQTL |
| rs7000029 | chr8:73620915:A:G | - | 0.0889638836470503 | 0.0367930948918254 | KIRC | Female-baised eQTL |
| rs12674775 | chr8:73649415:G:A | - | 0.0894392776453802 | 0.0370923618627736 | KIRC | Female-baised eQTL |
| rs57024488 | chr8:73647262:T:C | - | 0.0879467519370989 | 0.040748736429283 | KIRC | Female-baised eQTL |
| rs56190725 | chr8:73647989:A:G | - | 0.0879467519370989 | 0.040748736429283 | KIRC | Female-baised eQTL |
| rs59969061 | chr8:73648182:T:A | - | 0.0879467519370989 | 0.040748736429283 | KIRC | Female-baised eQTL |
| rs34389799 | chr8:73638208:T:C | - | 0.0884565935620609 | 0.0408972983114015 | KIRC | Female-baised eQTL |
| rs58865983 | chr8:73652082:T:C | - | 0.0883209776686656 | 0.0409613182579741 | KIRC | Female-baised eQTL |
| rs12680541 | chr8:73652234:A:C | - | 0.0883209776686656 | 0.0409613182579741 | KIRC | Female-baised eQTL |
| rs12676495 | chr8:73652436:G:A | - | 0.0883209776686656 | 0.0409613182579741 | KIRC | Female-baised eQTL |
| rs112555093 | chr8:73682357:T:C | - | 0.0873967826216253 | 0.0495681238713078 | KIRC | Female-baised eQTL |
| rs75031107 | chr8:69854483:C:T | - | 0.165311775905838 | 0.036126867983617 | BLCA | Female-baised eQTL |
| rs79053856 | chr8:81633551:C:T | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs79521042 | chr8:81638509:C:T | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs75014095 | chr8:81639392:G:A | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs76351724 | chr8:81641477:T:C | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs79114075 | chr8:81649736:G:A | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs78165366 | chr8:81651331:G:A | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs78840434 | chr8:81653001:T:C | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs77712751 | chr8:81653094:G:C | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs79407835 | chr8:81654243:C:T | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs149946133 | chr8:81655292:C:T | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs78891846 | chr8:81658679:A:G | - | 0.189767434435178 | 0.0461115540125348 | BLCA | Female-baised eQTL |
| rs79520423 | chr8:81632560:C:T | - | 0.190060188768366 | 0.0465179414856536 | BLCA | Female-baised eQTL |
| rs74980043 | chr8:81661330:G:C | - | 0.189539223099659 | 0.0471468385438545 | BLCA | Female-baised eQTL |
| rs76154096 | chr8:81667684:G:A | - | 0.189539223099659 | 0.0471468385438545 | BLCA | Female-baised eQTL |
| rs75980319 | chr8:81673029:T:G | - | 0.189539223099659 | 0.0471468385438545 | BLCA | Female-baised eQTL |
| rs78961078 | chr8:81680401:T:G | - | 0.189539223099659 | 0.0471468385438545 | BLCA | Female-baised eQTL |
| rs151111073 | chr8:81688569:G:A | - | 0.189539223099659 | 0.0471468385438545 | BLCA | Female-baised eQTL |
| rs55821789 | chr8:68729267:T:A | - | 0.081942766658949 | 0.000423406986290273 | LUAD | Female-baised eQTL |
| rs317944 | chr8:84430619:T:C | - | 0.0858105561431025 | 0.000440557549483953 | LUAD | Female-baised eQTL |
| rs17385104 | chr8:68541680:A:G | - | 0.0831003574108566 | 0.00054079638787616 | LUAD | Female-baised eQTL |
| rs76084817 | chr8:68549061:C:A | - | 0.0825881067756456 | 0.000630193420904456 | LUAD | Female-baised eQTL |
| rs698149 | chr8:84453443:A:T | - | 0.0871387316289754 | 0.000994908945710188 | LUAD | Female-baised eQTL |
| rs783790 | chr8:84444507:G:A | - | 0.088150484000608 | 0.00106432273285429 | LUAD | Female-baised eQTL |
| rs56048834 | chr8:68530584:G:A | - | 0.0795230427571578 | 0.0010956951116036 | LUAD | Female-baised eQTL |
| rs72663560 | chr8:75837172:T:A | - | 0.0714298226500019 | 0.00246274813036184 | LUAD | Female-baised eQTL |
| rs317941 | chr8:84428434:C:T | - | 0.0794446636695324 | 0.00272519220695027 | LUAD | Female-baised eQTL |
| rs317943 | chr8:84430447:G:C | - | 0.0794446636695324 | 0.00272519220695027 | LUAD | Female-baised eQTL |
| rs317945 | chr8:84432225:C:G | - | 0.0794446636695324 | 0.00272519220695027 | LUAD | Female-baised eQTL |
| rs1378616 | chr8:75116457:A:T | - | 0.0570624559036694 | 0.00305948797670971 | LUAD | Female-baised eQTL |
| rs10102787 | chr8:84278660:C:T | - | 0.0686081834030906 | 0.00346044901289232 | LUAD | Female-baised eQTL |
| rs28725264 | chr8:84256405:A:C | - | 0.0701993708050289 | 0.00373336209572586 | LUAD | Female-baised eQTL |
| rs10093323 | chr8:84383741:A:G | - | 0.0711394367031841 | 0.00890129332836528 | LUAD | Female-baised eQTL |
| rs317950 | chr8:84408686:G:A | - | 0.0710649991119575 | 0.0090647931386272 | LUAD | Female-baised eQTL |
| rs28380661 | chr8:84354488:C:G | - | 0.0718848868116336 | 0.00923698972973261 | LUAD | Female-baised eQTL |
| rs4568649 | chr8:71817044:C:T | - | -0.0445933784732128 | 0.00947529887767427 | LUAD | Female-baised eQTL |
| rs28693563 | chr8:84402263:A:G | - | 0.0733470369766955 | 0.00967157799834686 | LUAD | Female-baised eQTL |
| rs72656281 | chr8:69435504:C:T | - | 0.0685235451187105 | 0.0103410593230191 | LUAD | Female-baised eQTL |
| rs317951 | chr8:84409770:A:G | - | 0.0685169159927068 | 0.0127533463304273 | LUAD | Female-baised eQTL |
| rs10088997 | chr8:84242007:C:A | - | 0.0645292818548442 | 0.014817069696777 | LUAD | Female-baised eQTL |
| rs7017153 | chr8:71817716:A:G | - | -0.0429527790982071 | 0.0151882022557829 | LUAD | Female-baised eQTL |
| rs34641562 | chr8:76212852:T:A | - | 0.0456600867309453 | 0.0215358761576937 | LUAD | Female-baised eQTL |
| rs11994651 | chr8:76213330:C:T | - | 0.0456600867309453 | 0.0215358761576937 | LUAD | Female-baised eQTL |
| rs16912615 | chr8:84252976:T:G | - | 0.0558561913144973 | 0.0269322583568065 | LUAD | Female-baised eQTL |
| rs10094547 | chr8:84253548:A:G | - | 0.0557272751600033 | 0.0277061409830697 | LUAD | Female-baised eQTL |
| rs2977330 | chr8:75782427:C:T | - | 0.0391375465906016 | 0.041813927233402 | LUAD | Female-baised eQTL |
| rs10504616 | chr8:76305830:A:G | - | 0.0402643378556135 | 0.0439885381101796 | LUAD | Female-baised eQTL |
| rs17719800 | chr8:82332502:A:G | - | 0.095826661274145 | 0.0356414521801469 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs77443897 | chr8:70244904:C:A | - | 0.0882973943982878 | 0.00749658152934077 | KIRC | Male-baised eQTL |
| rs76419073 | chr8:70254655:T:C | - | 0.086618257477941 | 0.00874718815626186 | KIRC | Male-baised eQTL |
| rs78785828 | chr8:70257267:A:C | - | 0.086618257477941 | 0.00874718815626186 | KIRC | Male-baised eQTL |
| rs75494490 | chr8:70248437:A:G | - | 0.0853443985557655 | 0.00957968774864919 | KIRC | Male-baised eQTL |
| rs75217882 | chr8:70248741:G:A | - | 0.0853443985557655 | 0.00957968774864919 | KIRC | Male-baised eQTL |
| rs11989784 | chr8:70250165:G:A | - | 0.0844608860969204 | 0.00976997565452359 | KIRC | Male-baised eQTL |
| rs4738083 | chr8:70259829:C:G | - | 0.0844608860969204 | 0.00976997565452359 | KIRC | Male-baised eQTL |
| rs4737305 | chr8:70262424:C:T | - | 0.0844608860969204 | 0.00976997565452359 | KIRC | Male-baised eQTL |
| rs10504468 | chr8:70168791:A:G | - | 0.0881427095636554 | 0.00986697042392818 | KIRC | Male-baised eQTL |
| rs113426923 | chr8:70266118:C:G | - | 0.0837991643143577 | 0.0110128361784018 | KIRC | Male-baised eQTL |
| rs111623775 | chr8:70291821:C:T | - | 0.0829649654420071 | 0.0111799738808208 | KIRC | Male-baised eQTL |
| rs1460680 | chr8:70251533:T:C | - | 0.0827792113448851 | 0.0116252945497521 | KIRC | Male-baised eQTL |
| rs78765236 | chr8:70201651:A:G | - | 0.0830179865622016 | 0.0162494554283366 | KIRC | Male-baised eQTL |
| rs74532037 | chr8:70210406:C:T | - | 0.0830179865622016 | 0.0162494554283366 | KIRC | Male-baised eQTL |
| rs76720618 | chr8:70192469:G:C | - | 0.0807899880645451 | 0.0183060119029531 | KIRC | Male-baised eQTL |
| rs4738081 | chr8:70217591:T:A | - | 0.0814870670768681 | 0.0184383169665578 | KIRC | Male-baised eQTL |
| rs78869932 | chr8:70296574:A:C | - | 0.0814870670768681 | 0.0184383169665578 | KIRC | Male-baised eQTL |
| rs75920913 | chr8:70296985:G:A | - | 0.0814870670768681 | 0.0184383169665578 | KIRC | Male-baised eQTL |
| rs75767873 | chr8:70237072:A:G | - | 0.0803493371854631 | 0.0197853124961648 | KIRC | Male-baised eQTL |
| rs73684236 | chr8:70240516:T:A | - | 0.0781935907055964 | 0.0203100194559506 | KIRC | Male-baised eQTL |
| rs16936806 | chr8:70179217:T:C | - | 0.0820276885858396 | 0.0207657005911813 | KIRC | Male-baised eQTL |
| rs34507548 | chr8:70184117:G:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs76019984 | chr8:70184635:G:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs6980582 | chr8:70185529:T:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs16936816 | chr8:70190501:T:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs78815869 | chr8:70221556:A:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs78820765 | chr8:70232196:C:A | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs11986140 | chr8:70234153:T:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs4737303 | chr8:70234418:C:T | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs74950895 | chr8:70301429:A:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs79339601 | chr8:70309646:T:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs77707817 | chr8:70319868:T:C | - | 0.0782172539917884 | 0.0223595378928986 | KIRC | Male-baised eQTL |
| rs75161799 | chr8:70294961:C:T | - | 0.0788314244482854 | 0.0226057564879594 | KIRC | Male-baised eQTL |
| rs16936890 | chr8:70295192:T:C | - | 0.0788314244482854 | 0.0226057564879594 | KIRC | Male-baised eQTL |
| rs16936891 | chr8:70295545:A:T | - | 0.0788314244482854 | 0.0226057564879594 | KIRC | Male-baised eQTL |
| rs75272709 | chr8:70248740:G:A | - | 0.0780370127968182 | 0.0232203637818337 | KIRC | Male-baised eQTL |
| rs74957986 | chr8:70179102:T:A | - | 0.0820384301679292 | 0.0232912618227391 | KIRC | Male-baised eQTL |
| rs4738074 | chr8:70168467:A:G | - | 0.0776192111982873 | 0.0295506627407024 | KIRC | Male-baised eQTL |
| rs16936918 | chr8:70323085:G:A | - | 0.0718837019624022 | 0.029786582926405 | KIRC | Male-baised eQTL |
| rs76878493 | chr8:70180783:T:C | - | 0.0775106122289284 | 0.0330123304726134 | KIRC | Male-baised eQTL |
| rs4236983 | chr8:70220115:A:C | - | 0.0746681634239848 | 0.0351645153036686 | KIRC | Male-baised eQTL |
| rs16936844 | chr8:70237798:G:C | - | 0.0702526854266298 | 0.0385477211556815 | KIRC | Male-baised eQTL |
| rs77580813 | chr8:70187661:T:A | - | 0.0729804411850979 | 0.0411767642535668 | KIRC | Male-baised eQTL |
| rs16936902 | chr8:70298763:T:C | - | 0.0692624594857113 | 0.0414878462156993 | KIRC | Male-baised eQTL |
| rs78134400 | chr8:70295163:C:T | - | 0.0728967395416148 | 0.0454405459838758 | KIRC | Male-baised eQTL |
| rs77089419 | chr8:70218794:T:C | - | 0.0722698880804223 | 0.045603646009402 | KIRC | Male-baised eQTL |
| rs75919741 | chr8:70312196:A:G | - | 0.0722698880804223 | 0.045603646009402 | KIRC | Male-baised eQTL |
| rs74320599 | chr8:70271651:T:A | - | 0.072676071398629 | 0.047924388895749 | KIRC | Male-baised eQTL |
| rs7825320 | chr8:70283245:T:C | - | 0.072676071398629 | 0.047924388895749 | KIRC | Male-baised eQTL |
| rs7827089 | chr8:70286188:G:A | - | 0.072676071398629 | 0.047924388895749 | KIRC | Male-baised eQTL |
| rs73684239 | chr8:70248556:T:C | - | 0.070649153270124 | 0.0493238334836959 | KIRC | Male-baised eQTL |
| rs2943585 | chr8:75530965:G:A | - | 0.0820942399437861 | 0.01240744195816 | LUAD | Male-baised eQTL |
| rs2943550 | chr8:75540167:A:G | - | 0.0820942399437861 | 0.01240744195816 | LUAD | Male-baised eQTL |
| rs2943542 | chr8:75536609:C:A | - | 0.0819318891256347 | 0.0128563478240482 | LUAD | Male-baised eQTL |
| rs2977940 | chr8:75550263:A:C | - | 0.0778655106322702 | 0.0170460360418624 | LUAD | Male-baised eQTL |
| rs2977924 | chr8:75529082:C:G | - | 0.0763290563600621 | 0.018460504162236 | LUAD | Male-baised eQTL |
| rs2977925 | chr8:75529083:A:G | - | 0.0763290563600621 | 0.018460504162236 | LUAD | Male-baised eQTL |
| rs2977930 | chr8:75543103:A:C | - | 0.075246383464641 | 0.0242735373088616 | LUAD | Male-baised eQTL |
| rs2977933 | chr8:75546712:A:C | - | 0.075246383464641 | 0.0242735373088616 | LUAD | Male-baised eQTL |
| rs72658102 | chr8:75471502:G:T | - | 0.0830239007577842 | 0.0246963732013323 | LUAD | Male-baised eQTL |
| rs2926579 | chr8:75493579:T:C | - | 0.0860106950913598 | 0.0254679822275287 | LUAD | Male-baised eQTL |
| rs2926589 | chr8:75503877:C:T | - | 0.0860106950913598 | 0.0254679822275287 | LUAD | Male-baised eQTL |
| rs2941457 | chr8:75533096:T:A | - | 0.0859512436349295 | 0.0257897505701734 | LUAD | Male-baised eQTL |
| rs72660022 | chr8:75489122:C:A | - | 0.0697490558482193 | 0.0263893901504452 | LUAD | Male-baised eQTL |
| rs2941482 | chr8:75565760:T:G | - | 0.0780441308294705 | 0.0275179698546773 | LUAD | Male-baised eQTL |
| rs2977947 | chr8:75568119:C:G | - | 0.0780441308294705 | 0.0275179698546773 | LUAD | Male-baised eQTL |
| rs7826479 | chr8:75485670:T:A | - | 0.0678268775704293 | 0.0343907796414577 | LUAD | Male-baised eQTL |
| rs7842659 | chr8:75485700:C:T | - | 0.0669681001179034 | 0.0375034085160848 | LUAD | Male-baised eQTL |
| rs57832744 | chr8:75487858:G:A | - | 0.0669681001179034 | 0.0375034085160848 | LUAD | Male-baised eQTL |
| rs6991842 | chr8:75488419:G:A | - | 0.0669681001179034 | 0.0375034085160848 | LUAD | Male-baised eQTL |
| rs2977904 | chr8:75493347:C:T | - | 0.0669681001179034 | 0.0375034085160848 | LUAD | Male-baised eQTL |
| rs2941467 | chr8:75555779:T:G | - | 0.0730306585756361 | 0.0417762742735729 | LUAD | Male-baised eQTL |
| rs2977907 | chr8:75508025:A:T | - | 0.0661094909038489 | 0.0430948098512388 | LUAD | Male-baised eQTL |
| rs2977909 | chr8:75509770:A:T | - | 0.0661094909038489 | 0.0430948098512388 | LUAD | Male-baised eQTL |
| rs2138115 | chr8:75562557:A:G | - | 0.0726894390657586 | 0.043932365941869 | LUAD | Male-baised eQTL |
| rs2943582 | chr8:75527066:G:C | - | 0.0653488552077483 | 0.0459610369103526 | LUAD | Male-baised eQTL |
| rs80245535 | chr8:78906086:T:A | - | 0.0472340040104548 | 0.00562605147719133 | COAD | Male-baised eQTL |
| rs10448040 | chr8:78907582:C:T | - | 0.0474696569783281 | 0.00622199041547109 | COAD | Male-baised eQTL |
| rs12681214 | chr8:78863995:C:T | - | 0.0413681127618328 | 0.010822468225177 | COAD | Male-baised eQTL |
| rs56067827 | chr8:78876747:G:A | - | 0.0421596711193174 | 0.0133381057549141 | COAD | Male-baised eQTL |
| rs79485588 | chr8:78859722:A:G | - | 0.0421634633961585 | 0.0135102076028262 | COAD | Male-baised eQTL |
| rs12677636 | chr8:78887525:G:A | - | 0.0399813724762152 | 0.0145042546421361 | COAD | Male-baised eQTL |
| rs56099331 | chr8:78886059:C:T | - | 0.0399229357995049 | 0.0148556948980697 | COAD | Male-baised eQTL |
| rs1838257 | chr8:78864199:A:G | - | 0.0412025851136977 | 0.0156828111554171 | COAD | Male-baised eQTL |
| rs16906200 | chr8:78851498:G:A | - | 0.041688972653164 | 0.0162766273387643 | COAD | Male-baised eQTL |
| rs56126877 | chr8:78866725:A:C | - | 0.0411944453812077 | 0.0169825690718759 | COAD | Male-baised eQTL |
| rs79484511 | chr8:78868778:G:T | - | 0.0411194803291197 | 0.0172201619692757 | COAD | Male-baised eQTL |
| rs2120412 | chr8:78871125:T:C | - | 0.0410310045355903 | 0.0175269777597342 | COAD | Male-baised eQTL |
| rs114162961 | chr8:78872762:G:T | - | 0.0410310045355903 | 0.0175269777597342 | COAD | Male-baised eQTL |
| rs4739114 | chr8:78875089:G:C | - | 0.0410310045355903 | 0.0175269777597342 | COAD | Male-baised eQTL |
| rs75113778 | chr8:78862156:G:C | - | 0.0410337000868838 | 0.0177465036425451 | COAD | Male-baised eQTL |
| rs4739143 | chr8:78889443:A:G | - | 0.0381459985525945 | 0.0186301440929225 | COAD | Male-baised eQTL |
| rs12681387 | chr8:78895572:T:C | - | 0.0386740225610593 | 0.0209783810428109 | COAD | Male-baised eQTL |
| rs60612507 | chr8:78854843:C:T | - | 0.0405535006686902 | 0.0211940507861814 | COAD | Male-baised eQTL |
| rs16906260 | chr8:78887391:T:C | - | 0.029685184844178 | 0.0281540924187058 | COAD | Male-baised eQTL |
| rs55724729 | chr8:78882752:G:A | - | 0.0296022679972571 | 0.0282810723041674 | COAD | Male-baised eQTL |
| rs4739141 | chr8:78884421:C:T | - | 0.0296022679972571 | 0.0282810723041674 | COAD | Male-baised eQTL |
| rs55702228 | chr8:78886774:C:T | - | 0.0287448001560886 | 0.0309961339129159 | COAD | Male-baised eQTL |
| rs13264086 | chr8:83837407:T:C | - | 0.0315922098480584 | 0.0311918813347849 | COAD | Male-baised eQTL |
| rs117391356 | chr8:78872810:C:G | - | 0.0297322814114484 | 0.0344391150980404 | COAD | Male-baised eQTL |
| rs10957900 | chr8:78887856:C:T | - | 0.0285360698945663 | 0.0359557767982978 | COAD | Male-baised eQTL |
| rs7004870 | chr8:78889766:C:A | - | 0.0282737390466527 | 0.0387428900456351 | COAD | Male-baised eQTL |
| rs6987092 | chr8:78889835:T:C | - | 0.0270041981793937 | 0.0420627672146454 | COAD | Male-baised eQTL |
| rs75949159 | chr8:78863362:G:C | - | 0.034880250974278 | 0.0445525397483641 | COAD | Male-baised eQTL |
| rs11782275 | chr8:82436442:A:G | - | 0.0303278225805094 | 0.0446735971239928 | COAD | Male-baised eQTL |
| rs4739142 | chr8:78888177:C:G | - | 0.0329721574740115 | 0.0463875863806277 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000104381 |
| CpG Site: cg03753642 | |
| Position to Gene: gene | |
| Male Effect: -0.4071103464428 | |
| Female Effect: - | |
 | Gene ID: ENSG00000104381 |
| CpG Site: cg20546778 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: - | |
| Female Effect: -0.260578166124998 | |
 | Gene ID: ENSG00000104381 |
| CpG Site: cg20546778 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: - | |
| Female Effect: -0.392552432982041 | |
 | Gene ID: ENSG00000104381 |
| CpG Site: cg20546778 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.382676988217987 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg03753642 | chr8:74348987 | gene | -0.4071103464428 | 1.51868510968363e-07 | -0.6036875274858367 | 4.7098035607384036e-11 | PAAD |
| cg20546778 | chr8:74351364 | gene,exon,CDS | -0.382676988217987 | 4.81221127729629e-08 | -0.3663166663316617 | 1.0563785261479428e-10 | SKCM |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg20546778 | chr8:74351364 | gene,exon,CDS | -0.260578166124998 | 1.3097719816046e-05 | -0.3409033636734943 | 2.3337301153134847e-08 | LUAD |
| cg20546778 | chr8:74351364 | gene,exon,CDS | -0.392552432982041 | 3.20036108945903e-13 | -0.6707158401114868 | 9.667264186808107e-17 | STAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of GDAP1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000104381 | GDAP1 | C1842197 | Charcot-Marie-Tooth Disease, Recessive Intermediate A | 1 | CTD_human |
| ENSG00000104381 | GDAP1 | C1842983 | CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2K | 1 | CTD_human |
| ENSG00000104381 | GDAP1 | C1843183 | Charcot-Marie-Tooth disease, Type 4A, axonal form | 1 | CTD_human |
| ENSG00000104381 | GDAP1 | C1859198 | CHARCOT-MARIE-TOOTH DISEASE, TYPE 4A (disorder) | 1 | CTD_human |
