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Gene: ENSG00000103942 |
Summary for HOMER2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000103942 | Gene symbol | HOMER2 |
| Gene name | homer scaffold protein 2 | |
| HGNC | 17513 | |
| Entrez ID | 9455 | |
| Gene type | protein_coding | |
| Synonyms | HOMER2|CPD|Cupidin|Vesl-2|HOMER-2B|HOMER-2|HOMER-2A|DFNA68 | |
| UniProtAcc | Q9NSB8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000103942 | CPD | DB04489 | Guanidinoethylmercaptosuccinic acid | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for HOMER2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| HOMER2 | 2.05e+03 | -1.14e+00 | 2.20e-01 | -5.19e+00 | 2.05e-07 | 8.52e-07 | HNSC |
| HOMER2 | 1.20e+03 | -1.02e+00 | 3.99e-01 | -2.57e+00 | 1.02e-02 | 2.15e-02 | STAD |
| HOMER2 | 1.11e+03 | 1.04e+00 | 2.42e-01 | 4.29e+00 | 1.79e-05 | 6.98e-05 | KICH |
| HOMER2 | 2.28e+03 | -2.21e+00 | 5.17e-01 | -4.27e+00 | 1.94e-05 | 2.62e-04 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
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Sex-biased somatic mutation for HOMER2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for HOMER2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg07109804 | chr15:82985765 | CGI:chr15:82985838-82986493 | promoter,exon,gene body | 1.96e-01 | 3.22e-01 | -4.98e+00 | 6.37e-07 | 4.80e-06 | -1.26e-01 |
| LUSC | cg07109804 | chr15:82985765 | CGI:chr15:82985838-82986493 | promoter,exon,gene body | 1.51e-01 | 3.05e-01 | -4.29e+00 | 1.78e-05 | 5.26e-04 | -1.54e-01 |
| LUSC | cg01323954 | chr15:82985772 | CGI:chr15:82985838-82986493 | promoter,exon,gene body | 1.43e-01 | 3.09e-01 | -4.27e+00 | 1.98e-05 | 5.26e-04 | -1.66e-01 |
| LIHC | cg01323954 | chr15:82985772 | CGI:chr15:82985838-82986493 | promoter,exon,gene body | 1.33e-01 | 2.37e-01 | -6.14e+00 | 8.08e-10 | 1.11e-08 | -1.04e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for HOMER2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for HOMER2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LUAD | HOMER2-005 | chr15_82842595_- | 6.05e-01 | 4.57e-01 | 2.20e+00 | 2.76e-02 | 4.18e-02 | 1.48e-01 |
| LUAD | HOMER2-005 | chr15_82843034_- | 1.98e-01 | 2.98e-01 | -2.74e+00 | 6.20e-03 | 2.33e-02 | -1.00e-01 |
| THCA | HOMER2-005 | chr15_82842377_- | 1.61e-01 | 1.36e-01 | 2.29e+00 | 2.17e-02 | 4.91e-02 | 2.58e-02 |
| THCA | HOMER2-005 | chr15_82842390_- | 6.01e-01 | 5.71e-01 | 2.39e+00 | 1.68e-02 | 4.91e-02 | 2.96e-02 |
| LUSC | HOMER2-005 | chr15_82842433_- | 5.29e-01 | 4.36e-01 | 2.01e+00 | 4.44e-02 | 4.91e-02 | 9.28e-02 |
| STAD | HOMER2-005 | chr15_82843259_- | 2.06e-01 | 3.86e-01 | -2.69e+00 | 7.05e-03 | 4.96e-02 | -1.80e-01 |
| LIHC | HOMER2-005 | chr15_82842394_- | 2.04e-01 | 1.26e-01 | 2.06e+00 | 3.92e-02 | 4.75e-02 | 7.76e-02 |
| LIHC | HOMER2-005 | chr15_82842587_- | 7.47e-01 | 5.00e-01 | 3.26e+00 | 1.10e-03 | 3.89e-02 | 2.47e-01 |
| LIHC | HOMER2-005 | chr15_82842595_- | 8.50e-01 | 7.25e-01 | 2.79e+00 | 5.30e-03 | 3.89e-02 | 1.25e-01 |
| LIHC | HOMER2-005 | chr15_82843027_- | 2.30e-01 | 1.90e-01 | 2.22e+00 | 2.67e-02 | 4.56e-02 | 4.01e-02 |
| LIHC | HOMER2-005 | chr15_82843033_- | 2.06e-01 | 1.68e-01 | 2.18e+00 | 2.93e-02 | 4.56e-02 | 3.84e-02 |
| LIHC | HOMER2-005 | chr15_82843185_- | 6.50e-01 | 5.14e-01 | 3.44e+00 | 5.82e-04 | 3.89e-02 | 1.36e-01 |
| LIHC | HOMER2-005 | chr15_82843197_- | 5.19e-01 | 3.95e-01 | 2.02e+00 | 4.30e-02 | 4.82e-02 | 1.24e-01 |
| LIHC | HOMER2-005 | chr15_82843221_- | 7.25e-01 | 6.04e-01 | 2.16e+00 | 3.06e-02 | 4.57e-02 | 1.20e-01 |
| LIHC | HOMER2-005 | chr15_82843278_- | 8.22e-01 | 7.45e-01 | 2.65e+00 | 7.99e-03 | 4.07e-02 | 7.68e-02 |
| LIHC | HOMER2-005 | chr15_82843318_- | 7.39e-01 | 6.46e-01 | 2.33e+00 | 1.96e-02 | 4.41e-02 | 9.32e-02 |
| LIHC | HOMER2-005 | chr15_82843387_- | 6.19e-01 | 5.40e-01 | 2.12e+00 | 3.44e-02 | 4.69e-02 | 7.80e-02 |
| LIHC | HOMER2-005 | chr15_82843392_- | 7.24e-01 | 6.03e-01 | 3.23e+00 | 1.24e-03 | 3.89e-02 | 1.21e-01 |
| KIRP | HOMER2-005 | chr15_82842390_- | 5.94e-01 | 4.80e-01 | 2.35e+00 | 1.86e-02 | 4.53e-02 | 1.14e-01 |
| PAAD | HOMER2-005 | chr15_82842595_- | 5.08e-01 | 6.29e-01 | -1.99e+00 | 4.61e-02 | 4.90e-02 | -1.21e-01 |
| ESCA | HOMER2-005 | chr15_82843392_- | 8.25e-01 | 5.81e-01 | 2.47e+00 | 1.36e-02 | 4.99e-02 | 2.44e-01 |
| THYM | HOMER2-005 | chr15_82842432_- | 3.75e-01 | 6.89e-01 | -2.40e+00 | 1.63e-02 | 4.73e-02 | -3.14e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| THCA | HOMER2-005 | chr15_82842432_- | 6.01e-01 | 4.86e-01 | 2.46e+00 | 1.38e-02 | 2.29e-02 | 1.15e-01 |
| THCA | HOMER2-005 | chr15_82842974_- | 1.85e-01 | 1.42e-01 | 2.15e+00 | 3.18e-02 | 3.77e-02 | 4.29e-02 |
| HNSC | HOMER2-005 | chr15_82842390_- | 5.28e-01 | 3.90e-01 | 2.29e+00 | 2.18e-02 | 2.64e-02 | 1.38e-01 |
| HNSC | HOMER2-005 | chr15_82843278_- | 6.61e-01 | 7.81e-01 | -2.06e+00 | 3.90e-02 | 4.09e-02 | -1.20e-01 |
| HNSC | HOMER2-005 | chr15_82843315_- | 7.19e-01 | 5.75e-01 | 2.20e+00 | 2.80e-02 | 3.17e-02 | 1.45e-01 |
| HNSC | HOMER2-005 | chr15_82843318_- | 6.33e-01 | 4.83e-01 | 2.24e+00 | 2.50e-02 | 2.91e-02 | 1.50e-01 |
| STAD | HOMER2-005 | chr15_82842433_- | 5.60e-01 | 4.32e-01 | 3.09e+00 | 1.99e-03 | 1.18e-02 | 1.28e-01 |
| STAD | HOMER2-005 | chr15_82843185_- | 5.03e-01 | 3.41e-01 | 2.67e+00 | 7.53e-03 | 2.06e-02 | 1.62e-01 |
| LIHC | HOMER2-005 | chr15_82842974_- | 2.22e-01 | 3.16e-01 | -2.95e+00 | 3.23e-03 | 2.14e-02 | -9.41e-02 |
| LIHC | HOMER2-005 | chr15_82843315_- | 8.49e-01 | 7.58e-01 | 2.00e+00 | 4.57e-02 | 4.87e-02 | 9.18e-02 |
| ESCA | HOMER2-005 | chr15_82842587_- | 6.60e-01 | 4.10e-01 | 2.53e+00 | 1.15e-02 | 2.25e-02 | 2.51e-01 |
| ESCA | HOMER2-005 | chr15_82842974_- | 2.44e-01 | 1.68e-01 | 2.02e+00 | 4.32e-02 | 4.53e-02 | 7.61e-02 |
| ESCA | HOMER2-005 | chr15_82843197_- | 4.99e-01 | 3.49e-01 | 2.76e+00 | 5.86e-03 | 1.61e-02 | 1.50e-01 |
| ESCA | HOMER2-005 | chr15_82843221_- | 6.99e-01 | 4.15e-01 | 2.94e+00 | 3.23e-03 | 1.21e-02 | 2.84e-01 |
| ESCA | HOMER2-005 | chr15_82843275_- | 6.72e-01 | 4.60e-01 | 2.35e+00 | 1.88e-02 | 2.94e-02 | 2.12e-01 |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| BRCA | HOMER2-005 | chr15_82842390_- | 5.35e-01 | 4.85e-01 | 3.10e+00 | 1.91e-03 | 3.42e-03 | 5.06e-02 |
| BRCA | HOMER2-005 | chr15_82842432_- | 6.36e-01 | 5.77e-01 | 3.13e+00 | 1.75e-03 | 3.17e-03 | 5.88e-02 |
| BRCA | HOMER2-005 | chr15_82842433_- | 5.04e-01 | 4.55e-01 | 2.33e+00 | 1.99e-02 | 2.44e-02 | 4.90e-02 |
| BRCA | HOMER2-005 | chr15_82842551_- | 4.95e-01 | 3.72e-01 | 4.09e+00 | 4.40e-05 | 1.20e-04 | 1.23e-01 |
| BRCA | HOMER2-005 | chr15_82842587_- | 5.18e-01 | 3.72e-01 | 4.76e+00 | 1.92e-06 | 6.88e-06 | 1.46e-01 |
| BRCA | HOMER2-005 | chr15_82842595_- | 6.19e-01 | 5.07e-01 | 4.17e+00 | 2.98e-05 | 8.36e-05 | 1.13e-01 |
| BRCA | HOMER2-005 | chr15_82842974_- | 2.29e-01 | 1.66e-01 | 4.85e+00 | 1.25e-06 | 4.61e-06 | 6.31e-02 |
| BRCA | HOMER2-005 | chr15_82842998_- | 1.89e-01 | 1.21e-01 | 2.38e+00 | 1.73e-02 | 2.18e-02 | 6.80e-02 |
| BRCA | HOMER2-005 | chr15_82843027_- | 2.16e-01 | 1.53e-01 | 3.79e+00 | 1.53e-04 | 3.67e-04 | 6.28e-02 |
| BRCA | HOMER2-005 | chr15_82843033_- | 1.91e-01 | 1.19e-01 | 2.90e+00 | 3.76e-03 | 6.10e-03 | 7.19e-02 |
| BRCA | HOMER2-005 | chr15_82843034_- | 2.23e-01 | 1.62e-01 | 2.39e+00 | 1.70e-02 | 2.16e-02 | 6.15e-02 |
| BRCA | HOMER2-005 | chr15_82843185_- | 4.70e-01 | 3.22e-01 | 6.13e+00 | 8.77e-10 | 5.46e-09 | 1.47e-01 |
| BRCA | HOMER2-005 | chr15_82843197_- | 3.75e-01 | 2.67e-01 | 5.02e+00 | 5.29e-07 | 2.08e-06 | 1.08e-01 |
| BRCA | HOMER2-005 | chr15_82843198_- | 2.39e-01 | 1.48e-01 | 3.77e+00 | 1.61e-04 | 3.85e-04 | 9.05e-02 |
| BRCA | HOMER2-005 | chr15_82843221_- | 5.53e-01 | 3.92e-01 | 6.11e+00 | 9.99e-10 | 6.15e-09 | 1.62e-01 |
| BRCA | HOMER2-005 | chr15_82843225_- | 2.85e-01 | 1.51e-01 | 4.58e+00 | 4.65e-06 | 1.55e-05 | 1.33e-01 |
| BRCA | HOMER2-005 | chr15_82843250_- | 1.92e-01 | 1.26e-01 | 2.68e+00 | 7.46e-03 | 1.10e-02 | 6.60e-02 |
| BRCA | HOMER2-005 | chr15_82843275_- | 5.26e-01 | 4.00e-01 | 5.60e+00 | 2.19e-08 | 1.10e-07 | 1.25e-01 |
| BRCA | HOMER2-005 | chr15_82843278_- | 6.51e-01 | 5.37e-01 | 5.12e+00 | 3.07e-07 | 1.26e-06 | 1.13e-01 |
| BRCA | HOMER2-005 | chr15_82843315_- | 7.52e-01 | 6.52e-01 | 5.43e+00 | 5.64e-08 | 2.63e-07 | 1.00e-01 |
| BRCA | HOMER2-005 | chr15_82843318_- | 5.81e-01 | 4.84e-01 | 4.54e+00 | 5.52e-06 | 1.81e-05 | 9.63e-02 |
| BRCA | HOMER2-005 | chr15_82843328_- | 2.71e-01 | 2.00e-01 | 4.41e+00 | 1.03e-05 | 3.18e-05 | 7.03e-02 |
| BRCA | HOMER2-005 | chr15_82843387_- | 5.03e-01 | 4.57e-01 | 2.11e+00 | 3.49e-02 | 3.78e-02 | 4.59e-02 |
| BRCA | HOMER2-005 | chr15_82843392_- | 6.05e-01 | 5.53e-01 | 2.54e+00 | 1.11e-02 | 1.53e-02 | 5.23e-02 |
| THCA | HOMER2-005 | chr15_82842433_- | 5.45e-01 | 4.62e-01 | 3.40e+00 | 6.81e-04 | 2.58e-03 | 8.30e-02 |
| THCA | HOMER2-005 | chr15_82842517_- | 4.39e-01 | 3.42e-01 | 1.98e+00 | 4.76e-02 | 4.83e-02 | 9.65e-02 |
| THCA | HOMER2-005 | chr15_82842551_- | 5.07e-01 | 4.00e-01 | 2.99e+00 | 2.79e-03 | 7.07e-03 | 1.07e-01 |
| THCA | HOMER2-005 | chr15_82842595_- | 6.63e-01 | 5.22e-01 | 3.45e+00 | 5.54e-04 | 2.23e-03 | 1.41e-01 |
| THCA | HOMER2-005 | chr15_82843027_- | 1.70e-01 | 1.25e-01 | 2.69e+00 | 7.24e-03 | 1.38e-02 | 4.52e-02 |
| THCA | HOMER2-005 | chr15_82843221_- | 5.22e-01 | 3.96e-01 | 3.75e+00 | 1.75e-04 | 9.37e-04 | 1.27e-01 |
| THCA | HOMER2-005 | chr15_82843275_- | 5.57e-01 | 4.34e-01 | 4.43e+00 | 9.45e-06 | 1.09e-04 | 1.24e-01 |
| THCA | HOMER2-005 | chr15_82843278_- | 6.76e-01 | 5.88e-01 | 2.75e+00 | 5.96e-03 | 1.21e-02 | 8.87e-02 |
| THCA | HOMER2-005 | chr15_82843318_- | 6.37e-01 | 5.81e-01 | 2.37e+00 | 1.80e-02 | 2.51e-02 | 5.63e-02 |
| LIHC | HOMER2-005 | chr15_82843318_- | 6.46e-01 | 7.92e-01 | -2.54e+00 | 1.10e-02 | 3.10e-02 | -1.46e-01 |
| LIHC | HOMER2-005 | chr15_82843392_- | 6.03e-01 | 7.39e-01 | -2.44e+00 | 1.45e-02 | 3.29e-02 | -1.36e-01 |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for HOMER2 |
| TFs related to HOMER2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PCPG | ZNF235 | HOMER2 | 3.89e+00 | 9.81e-01 | 2.59e+00 | 8.81e-04 | Male-biased |
| HOMER2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for HOMER2 |
| RBPs related to ES in HOMER2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| HOMER2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12148361 | chr15:92182688:C:T | - | 0.180050231902981 | 0.0277900406646785 | LIHC | Female-baised eQTL |
| rs59804656 | chr15:92182794:T:C | - | 0.169233692112672 | 0.0482288038990639 | LIHC | Female-baised eQTL |
| rs56762083 | chr15:92182802:C:T | - | 0.169233692112672 | 0.0482288038990639 | LIHC | Female-baised eQTL |
| rs3743486 | chr15:74821617:G:C | - | 0.173914442716501 | 0.000600922315188547 | LGG | Female-baised eQTL |
| rs12594158 | chr15:74817612:C:T | - | 0.171212508769782 | 0.00129902817438019 | LGG | Female-baised eQTL |
| rs9796628 | chr15:74811713:G:A | - | 0.170552031802066 | 0.00143619487212538 | LGG | Female-baised eQTL |
| rs142999647 | chr15:74814211:G:C | - | 0.170552031802066 | 0.00143619487212538 | LGG | Female-baised eQTL |
| rs3803568 | chr15:74816295:G:A | - | 0.170552031802066 | 0.00143619487212538 | LGG | Female-baised eQTL |
| rs28397782 | chr15:74816816:G:T | - | 0.170552031802066 | 0.00143619487212538 | LGG | Female-baised eQTL |
| rs138110652 | chr15:74818008:G:A | - | 0.167037588459868 | 0.0032404061277553 | LGG | Female-baised eQTL |
| rs12441444 | chr15:74814499:G:A | - | 0.166775545391795 | 0.00335107599283446 | LGG | Female-baised eQTL |
| rs2229730 | chr15:74801048:C:T | - | 0.165145700690415 | 0.00414091842573275 | LGG | Female-baised eQTL |
| rs78045616 | chr15:74805539:G:A | - | 0.165145700690415 | 0.00414091842573275 | LGG | Female-baised eQTL |
| rs2899827 | chr15:74808786:A:G | - | 0.143318963374045 | 0.00797596008526668 | LGG | Female-baised eQTL |
| rs145895480 | chr15:74810495:G:A | - | 0.143318963374045 | 0.00797596008526668 | LGG | Female-baised eQTL |
| rs4886620 | chr15:74813537:G:A | - | 0.143318963374045 | 0.00797596008526668 | LGG | Female-baised eQTL |
| rs28431073 | chr15:74815296:A:C | - | 0.143318963374045 | 0.00797596008526668 | LGG | Female-baised eQTL |
| rs28577988 | chr15:74816909:T:C | - | 0.143318963374045 | 0.00797596008526668 | LGG | Female-baised eQTL |
| rs3743487 | chr15:74830515:C:T | - | 0.160381632471812 | 0.0181451438826701 | LGG | Female-baised eQTL |
| rs113106851 | chr15:74834888:G:A | - | 0.160381632471812 | 0.0181451438826701 | LGG | Female-baised eQTL |
| rs76516943 | chr15:74835198:C:A | - | 0.160381632471812 | 0.0181451438826701 | LGG | Female-baised eQTL |
| rs78315681 | chr15:74806571:C:G | - | 0.138131705838454 | 0.0184271329830869 | LGG | Female-baised eQTL |
| rs183551129 | chr15:74782041:G:T | - | 0.148555759980754 | 0.0397574684941501 | LGG | Female-baised eQTL |
| rs12439944 | chr15:74783309:G:T | - | 0.148555759980754 | 0.0397574684941501 | LGG | Female-baised eQTL |
| rs28583379 | chr15:74773577:G:C | - | 0.148328011965234 | 0.0406042584549139 | LGG | Female-baised eQTL |
| rs6496799 | chr15:91425310:A:G | - | -0.0663835715804222 | 0.0350571316661971 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000103942 |
| CpG Site: cg14914238 | |
| Position to Gene: gene | |
| Male Effect: -0.378524664828271 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg14914238 | chr15:82951569 | gene | -0.378524664828271 | 5.81911060689774e-06 | -0.37155815579377793 | 1.0429837104004842e-08 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of HOMER2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000103942 | HOMER2 | C0009171 | Cocaine Abuse | 1 | CTD_human |
| ENSG00000103942 | HOMER2 | C0036341 | Schizophrenia | 1 | PSYGENET |
| ENSG00000103942 | HOMER2 | C0236736 | Cocaine-Related Disorders | 1 | CTD_human |
| ENSG00000103942 | HOMER2 | C0600427 | Cocaine Dependence | 1 | CTD_human |
| ENSG00000103942 | HOMER2 | C4225240 | DEAFNESS, AUTOSOMAL DOMINANT 68 | 1 | CTD_human |
