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Gene: ENSG00000103056 |
Summary for SMPD3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000103056 | Gene symbol | SMPD3 |
| Gene name | sphingomyelin phosphodiesterase 3 | |
| HGNC | 14240 | |
| Entrez ID | 55512 | |
| Gene type | protein_coding | |
| Synonyms | SMPD3|NSMASE2 | |
| UniProtAcc | Q9NY59 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000103056 | SMPD3 | DB00144 | Phosphatidyl serine | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SMPD3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for SMPD3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SMPD3 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg06106242 | chr16:68449038 | CGI:chr16:68446961-68448919 | promoter | 5.71e-01 | 4.65e-01 | 2.17e+00 | 3.01e-02 | 4.10e-02 | 1.06e-01 |
| BRCA | cg12136772 | chr16:68447910 | CGI:chr16:68446961-68448919 | promoter,gene body | 4.43e-01 | 5.75e-01 | -2.15e+00 | 3.17e-02 | 4.19e-02 | -1.32e-01 |
| KIRC | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 5.69e-01 | 6.77e-01 | -4.80e+00 | 1.55e-06 | 1.18e-05 | -1.08e-01 |
| THCA | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 4.24e-01 | 5.41e-01 | -4.75e+00 | 2.02e-06 | 9.06e-06 | -1.16e-01 |
| HNSC | cg03412735 | chr16:68448615 | CGI:chr16:68446961-68448919 | UTR,promoter,exon,gene body | 4.09e-01 | 2.56e-01 | 3.81e+00 | 1.41e-04 | 9.05e-04 | 1.53e-01 |
| SARC | cg03412735 | chr16:68448615 | CGI:chr16:68446961-68448919 | UTR,promoter,exon,gene body | 1.71e-01 | 2.86e-01 | 1.15e+01 | 2.32e-30 | 6.04e-29 | -1.16e-01 |
| ESCA | cg03412735 | chr16:68448615 | CGI:chr16:68446961-68448919 | UTR,promoter,exon,gene body | 1.65e-01 | 2.66e-01 | 2.12e+00 | 3.41e-02 | 4.54e-02 | -1.00e-01 |
| LAML | cg05144928 | chr16:68447640 | CGI:chr16:68446961-68448919 | promoter,gene body | 4.65e-01 | 6.25e-01 | -3.50e+00 | 4.63e-04 | 1.45e-03 | -1.61e-01 |
| MESO | cg19297232 | chr16:68449118 | CGI:chr16:68446961-68448919 | promoter | 4.66e-01 | 6.45e-01 | -2.88e+00 | 3.92e-03 | 1.54e-02 | -1.79e-01 |
| UVM | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.13e-01 | 4.81e-01 | -2.69e+00 | 7.12e-03 | 1.67e-02 | -1.67e-01 |
| UVM | cg10556064 | chr16:68447586 | CGI:chr16:68446961-68448919 | promoter,gene body | 2.94e-01 | 4.59e-01 | -3.00e+00 | 2.68e-03 | 7.42e-03 | -1.65e-01 |
| DLBC | cg03412735 | chr16:68448615 | CGI:chr16:68446961-68448919 | UTR,promoter,exon,gene body | 2.92e-01 | 1.50e-01 | 3.64e+00 | 2.71e-04 | 1.13e-03 | 1.42e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg08890345 | chr16:68447345 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.30e-01 | 1.96e-01 | 3.11e+00 | 1.87e-03 | 2.70e-03 | 1.34e-01 |
| KIRC | cg19297232 | chr16:68449118 | CGI:chr16:68446961-68448919 | promoter | 5.70e-01 | 4.58e-01 | 2.70e+00 | 6.99e-03 | 8.70e-03 | 1.11e-01 |
| THCA | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 5.41e-01 | 3.55e-01 | 2.84e+00 | 4.49e-03 | 9.31e-03 | 1.86e-01 |
| THCA | cg10556064 | chr16:68447586 | CGI:chr16:68446961-68448919 | promoter,gene body | 5.26e-01 | 4.09e-01 | 2.30e+00 | 2.16e-02 | 2.84e-02 | 1.17e-01 |
| THCA | cg19297232 | chr16:68449118 | CGI:chr16:68446961-68448919 | promoter | 4.91e-01 | 3.57e-01 | 2.45e+00 | 1.43e-02 | 2.13e-02 | 1.34e-01 |
| HNSC | cg22116290 | chr16:68448065 | CGI:chr16:68446961-68448919 | promoter,gene body | 2.11e-01 | 8.15e-02 | 3.28e+00 | 1.03e-03 | 1.85e-03 | 1.30e-01 |
| LUSC | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 7.18e-01 | 3.98e-01 | 3.60e+00 | 3.20e-04 | 1.26e-03 | 3.20e-01 |
| LUSC | cg10556064 | chr16:68447586 | CGI:chr16:68446961-68448919 | promoter,gene body | 6.81e-01 | 4.38e-01 | 3.43e+00 | 6.06e-04 | 1.87e-03 | 2.43e-01 |
| LUSC | cg04464276 | chr16:68447146 | CGI:chr16:68446961-68448919 | promoter,gene body | 2.89e-01 | 1.58e-01 | 2.45e+00 | 1.41e-02 | 1.81e-02 | 1.31e-01 |
| LUSC | cg05948940 | chr16:68447439 | CGI:chr16:68446961-68448919 | promoter,gene body | 2.00e-01 | 6.90e-02 | 2.19e+00 | 2.88e-02 | 3.20e-02 | 1.31e-01 |
| LUSC | cg12136772 | chr16:68447910 | CGI:chr16:68446961-68448919 | promoter,gene body | 4.91e-01 | 2.83e-01 | 3.56e+00 | 3.76e-04 | 1.39e-03 | 2.08e-01 |
| COAD | cg10556064 | chr16:68447586 | CGI:chr16:68446961-68448919 | promoter,gene body | 8.17e-01 | 7.11e-01 | 3.81e+00 | 1.40e-04 | 4.57e-04 | 1.06e-01 |
| COAD | cg05948940 | chr16:68447439 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.14e-01 | 9.85e-02 | 2.29e+00 | 2.22e-02 | 2.68e-02 | 2.16e-01 |
| COAD | cg07461772 | chr16:68448906 | CGI:chr16:68446961-68448919 | promoter | 1.21e-01 | 2.71e-01 | -3.54e+00 | 3.96e-04 | 1.06e-03 | -1.50e-01 |
| BLCA | cg04464276 | chr16:68447146 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.94e-01 | 1.56e-01 | 3.11e+00 | 1.86e-03 | 3.70e-03 | 2.38e-01 |
| LIHC | cg08694014 | chr16:68448688 | CGI:chr16:68446961-68448919 | promoter | 2.66e-01 | 5.49e-02 | 2.60e+00 | 9.20e-03 | 1.13e-02 | 2.11e-01 |
| LIHC | cg15201635 | chr16:68448734 | CGI:chr16:68446961-68448919 | promoter | 3.79e-01 | 1.77e-01 | 3.11e+00 | 1.86e-03 | 2.75e-03 | 2.02e-01 |
| CHOL | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 6.91e-01 | 4.57e-01 | 2.14e+00 | 3.25e-02 | 3.87e-02 | 2.35e-01 |
| CHOL | cg10556064 | chr16:68447586 | CGI:chr16:68446961-68448919 | promoter,gene body | 6.69e-01 | 4.50e-01 | 2.14e+00 | 3.25e-02 | 3.87e-02 | 2.18e-01 |
| CHOL | cg15201635 | chr16:68448734 | CGI:chr16:68446961-68448919 | promoter | 6.90e-02 | 1.91e-01 | -3.54e+00 | 4.02e-04 | 8.32e-03 | -1.22e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg00891541 | chr16:68447584 | CGI:chr16:68446961-68448919 | promoter,gene body | 6.69e-01 | 4.15e-01 | 1.03e+01 | 5.40e-25 | 4.59e-24 | 2.54e-01 |
| BRCA | cg10556064 | chr16:68447586 | CGI:chr16:68446961-68448919 | promoter,gene body | 6.38e-01 | 4.31e-01 | 9.90e+00 | 4.31e-23 | 3.06e-22 | 2.07e-01 |
| BRCA | cg04464276 | chr16:68447146 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.32e-01 | 1.19e-01 | 8.76e+00 | 1.92e-18 | 9.15e-18 | 2.13e-01 |
| BRCA | cg08890345 | chr16:68447345 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.66e-01 | 2.31e-01 | 4.92e+00 | 8.52e-07 | 1.60e-06 | 1.34e-01 |
| BRCA | cg05948940 | chr16:68447439 | CGI:chr16:68446961-68448919 | promoter,gene body | 2.45e-01 | 4.75e-02 | 8.17e+00 | 2.98e-16 | 1.19e-15 | 1.97e-01 |
| BRCA | cg12136772 | chr16:68447910 | CGI:chr16:68446961-68448919 | promoter,gene body | 4.43e-01 | 2.62e-01 | 7.90e+00 | 2.71e-15 | 1.01e-14 | 1.82e-01 |
| BRCA | cg03412735 | chr16:68448615 | CGI:chr16:68446961-68448919 | UTR,promoter,exon,gene body | 2.91e-01 | 1.60e-01 | 6.40e+00 | 1.54e-10 | 3.99e-10 | 1.31e-01 |
| KIRC | cg12136772 | chr16:68447910 | CGI:chr16:68446961-68448919 | promoter,gene body | 3.25e-01 | 2.15e-01 | 2.03e+00 | 4.20e-02 | 4.44e-02 | 1.10e-01 |
| HNSC | cg05676789 | chr16:68448241 | CGI:chr16:68446961-68448919 | promoter,gene body | 1.63e-01 | 2.85e-02 | 2.31e+00 | 2.10e-02 | 2.84e-02 | 1.34e-01 |
| HNSC | cg17217677 | chr16:68449291 | CGI:chr16:68446961-68448919 | promoter | 7.68e-01 | 6.47e-01 | 3.27e+00 | 1.08e-03 | 9.05e-03 | 1.21e-01 |
| COAD | cg19297232 | chr16:68449118 | CGI:chr16:68446961-68448919 | promoter | 7.62e-01 | 8.97e-01 | -2.76e+00 | 5.82e-03 | 1.06e-02 | -1.35e-01 |
| KIRP | cg05948940 | chr16:68447439 | CGI:chr16:68446961-68448919 | promoter,gene body | 1.50e-01 | 3.45e-02 | 2.07e+00 | 3.81e-02 | 4.14e-02 | 1.16e-01 |
| KIRP | cg07461772 | chr16:68448906 | CGI:chr16:68446961-68448919 | promoter | 1.33e-01 | 2.32e-02 | 2.22e+00 | 2.67e-02 | 3.25e-02 | 1.09e-01 |
| KIRP | cg17217677 | chr16:68449291 | CGI:chr16:68446961-68448919 | promoter | 7.42e-01 | 6.17e-01 | 3.61e+00 | 3.07e-04 | 2.00e-03 | 1.25e-01 |
Top |
Exon skipping events with PSI in TCGA for SMPD3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for SMPD3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for SMPD3 |
| TFs related to SMPD3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SMPD3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SMPD3 |
| RBPs related to ES in SMPD3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SMPD3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6564944 | chr16:74126062:T:C | - | -0.664959550308739 | 0.00745423683705357 | GBM | Female-baised eQTL |
| rs9888759 | chr16:74122840:C:T | - | -0.66300156130627 | 0.00798990008573422 | GBM | Female-baised eQTL |
| rs6564927 | chr16:74113458:C:A | - | -0.662288777604338 | 0.00806495850576057 | GBM | Female-baised eQTL |
| rs6564930 | chr16:74118565:C:T | - | -0.662288777604338 | 0.00806495850576057 | GBM | Female-baised eQTL |
| rs75273855 | chr16:70412297:T:C | - | 0.855293036589883 | 0.0340563632538743 | GBM | Female-baised eQTL |
| rs2903523 | chr16:70412976:C:T | - | 0.855293036589883 | 0.0340563632538743 | GBM | Female-baised eQTL |
| rs58684580 | chr16:70410039:T:C | - | 0.851770730291466 | 0.0364514143378601 | GBM | Female-baised eQTL |
| rs56097211 | chr16:68164185:T:C | - | 0.0910778980251572 | 0.0369512816195529 | COAD | Female-baised eQTL |
| rs73612208 | chr16:68172941:G:A | - | 0.0902199953277638 | 0.0389795430799296 | COAD | Female-baised eQTL |
| rs8044014 | chr16:68175969:T:C | - | 0.0902199953277638 | 0.0389795430799296 | COAD | Female-baised eQTL |
| rs8044558 | chr16:68176262:T:C | - | 0.0902199953277638 | 0.0389795430799296 | COAD | Female-baised eQTL |
| rs28548264 | chr16:68177418:A:G | - | 0.0902199953277638 | 0.0389795430799296 | COAD | Female-baised eQTL |
| rs9922165 | chr16:68147274:C:A | - | 0.0897610339861299 | 0.0418366869641338 | COAD | Female-baised eQTL |
| rs9938553 | chr16:68149161:T:A | - | 0.0897610339861299 | 0.0418366869641338 | COAD | Female-baised eQTL |
| rs2418738 | chr16:68088701:G:C | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs28508024 | chr16:68092703:T:C | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs9932251 | chr16:68097829:G:A | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs7192187 | chr16:68098206:T:C | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs8058690 | chr16:68102719:T:G | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs7194894 | chr16:68111159:C:T | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs8044328 | chr16:68112956:G:C | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs73612690 | chr16:68119297:G:A | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs112099181 | chr16:68120327:T:C | - | 0.0883161188098272 | 0.0464008577037511 | COAD | Female-baised eQTL |
| rs4359427 | chr16:68168844:C:T | - | 0.0884086758362479 | 0.0490732657826525 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs8057962 | chr16:77723956:C:G | - | 0.0911553635375751 | 0.0380169192391427 | LUAD | Male-baised eQTL |
| rs28681645 | chr16:77725154:C:T | - | 0.0881997896844221 | 0.0449902058064635 | LUAD | Male-baised eQTL |
| rs35578026 | chr16:78228747:A:G | - | 0.184179036401236 | 2.7190180768455e-05 | COAD | Male-baised eQTL |
| rs71396167 | chr16:78230533:A:G | - | 0.153397925777869 | 0.000131449068917961 | COAD | Male-baised eQTL |
| rs34626702 | chr16:78230963:A:G | - | 0.15329845979102 | 0.000134823228364437 | COAD | Male-baised eQTL |
| rs71396166 | chr16:78230320:G:T | - | 0.148553340533873 | 0.000328447845912199 | COAD | Male-baised eQTL |
| rs117508347 | chr16:78230176:G:A | - | 0.148455466508085 | 0.000336167983921503 | COAD | Male-baised eQTL |
| rs34707065 | chr16:78230279:G:T | - | 0.148455466508085 | 0.000336167983921503 | COAD | Male-baised eQTL |
| rs12918190 | chr16:78231526:G:A | - | 0.147101007916693 | 0.000539000783633129 | COAD | Male-baised eQTL |
| rs12923828 | chr16:78231600:T:A | - | 0.146994264675715 | 0.000551414482572804 | COAD | Male-baised eQTL |
| rs35530243 | chr16:78231683:A:G | - | 0.146994264675715 | 0.000551414482572804 | COAD | Male-baised eQTL |
| rs36060834 | chr16:78231686:A:G | - | 0.146994264675715 | 0.000551414482572804 | COAD | Male-baised eQTL |
| rs12921948 | chr16:78228496:C:T | - | 0.168332052968233 | 0.00090054020949536 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000103056 |
| CpG Site: cg03873826 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.46462312050862 | |
 | Gene ID: ENSG00000103056 |
| CpG Site: cg19297232 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.247160778716617 | |
 | Gene ID: ENSG00000103056 |
| CpG Site: cg00891541 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.36232292935787 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg00891541 | chr16:68447584 | gene,promoter | -0.36232292935787 | 1.4102369250278e-05 | -0.3554128768360457 | 4.847150005239039e-08 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg03873826 | chr16:68373408 | gene | -0.46462312050862 | 3.95490982908876e-16 | -0.8100862697482444 | 9.060237644374609e-20 | PAAD |
| cg19297232 | chr16:68449118 | promoter | -0.247160778716617 | 2.21527114034209e-06 | -0.6023366444159161 | 3.404816904701303e-09 | PAAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of SMPD3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000103056 | SMPD3 | C0023418 | leukemia | 1 | CTD_human |
| ENSG00000103056 | SMPD3 | C2713368 | Hematopoetic Myelodysplasia | 1 | CTD_human |
| ENSG00000103056 | SMPD3 | C3463824 | MYELODYSPLASTIC SYNDROME | 1 | CTD_human |
