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Gene: ENSG00000102038

Summary for SMARCA1

Gene summary

Gene information	Ensembl ID	ENSG00000102038
	Gene symbol	SMARCA1
	Gene name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
	HGNC	11097
	Entrez ID	6594
	Gene type	protein_coding
	Synonyms	SMARCA1\|SNF2LB\|NURF140\|ISWI\|SWI\|hSNF2L
	UniProtAcc	P28370

Drugs associated with this gene(DrugBank).

Gene ID

Gene Symbol

Drug ID

Drug Name

Drug Type

Cancer therapeutic drugs associated with this gene(NCI).

Gene ID

Gene Name

Drug ID

Drug Name

Drug Type

Cancer

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Structure and expression level for SMARCA1

AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.

Landscape of gene expressions across multiple cancer types.

Differentially expressed gene analysis between tumor male and tumor female samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

Differentially expressed gene analysis between tumor male and normal male samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
SMARCA1	2.74e+03	-1.04e+00	3.01e-01	-3.44e+00	5.75e-04	2.05e-03	BLCA
SMARCA1	2.86e+03	-1.48e+00	3.67e-01	-4.03e+00	5.59e-05	2.62e-04	CHOL

Differentially expressed gene analysis between tumor female and normal female samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
SMARCA1	3.53e+02	-1.92e+00	3.85e-01	-4.98e+00	6.48e-07	5.93e-06	READ

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Sex-biased somatic mutation for SMARCA1

∗For more information on exon skipping events please check the ExonskipDB database.

Gene ID

Cancer Type

Hugo Symbol

Male

Female

pval

ci.up

ci.low

adjPval

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DNA methylation with beta values for SMARCA1

Landscape of DNA methylation across multiple cancer types.

Differentially expressed CpG sites between male tumor and female tumor patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	6.40e-01	2.12e-01	4.03e+00	5.56e-05	1.07e-03	4.29e-01
BRCA	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.29e-01	1.10e-01	4.01e+00	6.07e-05	1.12e-03	4.19e-01
BRCA	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	6.03e-01	1.35e-01	4.04e+00	5.26e-05	1.02e-03	4.68e-01
BRCA	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	3.62e-01	9.20e-02	2.69e+00	7.05e-03	2.33e-02	2.70e-01
BRCA	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.12e-01	7.05e-02	5.15e+00	2.62e-07	1.16e-05	4.42e-01
BRCA	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.10e-01	1.44e-01	3.99e+00	6.54e-05	1.18e-03	1.66e-01
BRCA	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.85e-01	1.18e-01	4.02e+00	5.88e-05	1.11e-03	3.66e-01
BRCA	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.83e-01	1.46e-01	4.02e+00	5.74e-05	1.10e-03	3.37e-01
BRCA	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	6.27e-01	3.95e-01	2.73e+00	6.26e-03	2.23e-02	2.32e-01
LUAD	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.45e-01	1.18e-01	9.48e+00	2.60e-21	4.30e-20	3.27e-01
LUAD	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	5.02e-01	3.93e-01	8.22e+00	1.99e-16	3.00e-15	1.09e-01
LGG	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.23e-01	4.68e-02	1.98e+01	4.12e-87	2.64e-85	4.77e-01
LGG	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.26e-01	1.20e-01	5.31e+00	1.10e-07	5.84e-07	3.06e-01
LGG	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.31e-01	3.05e-02	1.98e+01	3.52e-87	2.64e-85	5.01e-01
LGG	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	4.39e-01	3.16e-02	1.97e+01	1.19e-86	5.44e-85	4.07e-01
LGG	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	3.72e-01	1.12e-01	1.04e+01	1.71e-25	1.28e-24	2.61e-01
LGG	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.32e-01	5.09e-02	1.98e+01	3.56e-87	2.64e-85	4.81e-01
LGG	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.24e-01	6.45e-02	1.96e+01	2.44e-85	7.60e-84	2.60e-01
LGG	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.69e-01	3.92e-02	1.98e+01	3.52e-87	2.64e-85	4.29e-01
LGG	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.81e-01	5.06e-02	1.98e+01	3.52e-87	2.64e-85	4.30e-01
LGG	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.83e-01	8.47e-02	1.81e+01	1.92e-73	3.27e-72	2.99e-01
LGG	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	4.74e-01	2.74e-01	1.20e+01	2.30e-33	1.91e-32	2.00e-01
HNSC	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.12e-01	1.23e-01	1.09e+01	1.38e-27	2.65e-26	2.89e-01
LUSC	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.60e-01	2.62e-01	1.25e+01	4.12e-36	6.00e-35	2.98e-01
LUSC	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.11e-01	1.17e-01	1.04e+01	1.57e-25	1.85e-24	2.94e-01
LUSC	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.26e-01	3.30e-02	1.45e+01	1.73e-47	1.26e-45	4.93e-01
LUSC	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	4.91e-01	1.24e-01	1.27e+01	4.57e-37	6.82e-36	3.67e-01
LUSC	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	3.40e-01	1.04e-01	1.18e+01	4.58e-32	6.12e-31	2.36e-01
LUSC	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.69e-01	5.48e-02	1.45e+01	1.78e-47	1.26e-45	4.15e-01
LUSC	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	2.94e-01	6.49e-02	1.45e+01	1.62e-47	1.26e-45	2.29e-01
LUSC	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.60e-01	6.63e-02	1.43e+01	3.80e-46	9.14e-45	3.93e-01
LUSC	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.38e-01	1.12e-01	1.42e+01	8.26e-46	1.88e-44	3.26e-01
LUSC	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.77e-01	1.27e-01	1.21e+01	7.60e-34	1.06e-32	2.51e-01
SKCM	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.40e-01	2.67e-01	1.22e+01	3.53e-34	3.73e-33	2.73e-01
SKCM	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	4.26e-01	3.48e-02	1.76e+01	2.60e-69	6.68e-68	3.91e-01
SKCM	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	4.72e-01	1.86e-01	1.19e+01	9.98e-33	1.02e-31	2.87e-01
SKCM	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	2.71e-01	1.31e-01	8.61e+00	7.55e-18	5.52e-17	1.40e-01
SKCM	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.09e-01	5.57e-02	1.79e+01	1.23e-71	3.97e-70	3.54e-01
SKCM	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	2.43e-01	6.78e-02	1.72e+01	1.49e-66	3.30e-65	1.75e-01
SKCM	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.25e-01	6.06e-02	1.76e+01	1.21e-69	3.20e-68	3.64e-01
SKCM	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.17e-01	9.94e-02	1.71e+01	1.66e-65	3.54e-64	3.18e-01
SKCM	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.61e-01	2.15e-01	9.69e+00	3.46e-22	2.81e-21	1.46e-01
STAD	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	6.09e-01	3.91e-01	8.15e+00	3.76e-16	3.70e-15	2.18e-01
STAD	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.64e-01	1.18e-01	3.50e+00	4.60e-04	2.09e-03	3.46e-01
STAD	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.69e-01	1.16e-01	1.23e+01	1.38e-34	2.39e-33	4.53e-01
STAD	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	5.56e-01	2.72e-01	8.87e+00	7.47e-19	8.26e-18	2.84e-01
STAD	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	3.96e-01	1.59e-01	7.93e+00	2.13e-15	2.03e-14	2.37e-01
STAD	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.18e-01	1.28e-01	1.24e+01	2.54e-35	4.48e-34	3.91e-01
STAD	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.42e-01	1.30e-01	1.19e+01	8.20e-33	1.36e-31	2.12e-01
STAD	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	5.03e-01	1.57e-01	1.21e+01	1.12e-33	1.89e-32	3.46e-01
STAD	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.74e-01	2.06e-01	1.09e+01	7.30e-28	1.07e-26	2.68e-01
STAD	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	4.35e-01	2.06e-01	8.86e+00	8.29e-19	9.15e-18	2.28e-01
LIHC	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	4.46e-01	2.50e-01	9.92e+00	3.55e-23	1.01e-21	1.96e-01
SARC	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	4.90e-01	1.78e-01	1.12e+01	4.79e-29	1.15e-27	3.13e-01
SARC	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	4.15e-01	3.52e-02	1.29e+01	4.65e-38	1.93e-36	3.80e-01
SARC	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	3.84e-01	9.51e-02	1.08e+01	2.51e-27	5.42e-26	2.88e-01
SARC	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.14e-01	6.09e-02	1.34e+01	8.88e-41	5.17e-39	3.54e-01
SARC	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	2.31e-01	7.31e-02	1.27e+01	5.64e-37	2.16e-35	1.58e-01
SARC	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.19e-01	4.85e-02	1.38e+01	3.84e-43	7.48e-41	3.70e-01
SARC	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.87e-01	7.81e-02	1.33e+01	2.27e-40	1.24e-38	3.09e-01
SARC	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	2.98e-01	1.38e-01	6.23e+00	4.67e-10	4.16e-09	1.60e-01
PCPG	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	3.95e-01	5.41e-02	1.16e+01	5.67e-31	2.07e-29	3.40e-01
PCPG	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	2.79e-01	2.98e-02	1.16e+01	6.06e-31	2.16e-29	2.49e-01
PCPG	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	2.49e-01	3.27e-02	1.16e+01	7.13e-31	2.38e-29	2.16e-01
PCPG	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.19e-01	5.47e-02	1.16e+01	3.83e-31	1.92e-29	3.65e-01
PCPG	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.59e-01	4.10e-02	1.16e+01	3.96e-31	1.92e-29	3.18e-01
PCPG	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.88e-01	5.31e-02	1.16e+01	3.83e-31	1.92e-29	3.35e-01
PCPG	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	2.09e-01	7.81e-02	9.48e+00	2.49e-21	2.61e-20	1.31e-01
PCPG	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	3.09e-01	1.50e-01	7.87e+00	3.56e-15	2.51e-14	1.59e-01
PAAD	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.67e-01	2.55e-01	9.54e+00	1.49e-21	2.39e-20	3.12e-01
PAAD	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.51e-01	3.10e-02	1.15e+01	2.32e-30	1.01e-28	5.20e-01
PAAD	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	4.96e-01	1.30e-01	9.85e+00	7.15e-23	1.22e-21	3.66e-01
PAAD	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	4.03e-01	1.24e-01	3.51e+00	4.50e-04	2.27e-03	2.79e-01
PAAD	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.42e-01	5.91e-02	1.15e+01	2.03e-30	1.01e-28	4.83e-01
PAAD	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.22e-01	7.05e-02	1.13e+01	1.28e-29	3.90e-28	2.52e-01
PAAD	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.83e-01	5.51e-02	1.15e+01	2.24e-30	1.01e-28	4.28e-01
PAAD	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.54e-01	8.44e-02	1.14e+01	4.11e-30	1.44e-28	3.70e-01
PAAD	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	4.28e-01	1.32e-01	9.59e+00	9.20e-22	1.50e-20	2.96e-01
READ	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	6.50e-01	4.19e-01	4.09e+00	4.40e-05	2.18e-04	2.31e-01
READ	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	3.60e-01	1.02e-01	6.57e+00	4.99e-11	4.28e-10	2.58e-01
READ	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.31e-01	3.04e-02	8.44e+00	3.11e-17	5.17e-16	5.01e-01
READ	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	6.30e-01	3.30e-01	4.56e+00	5.02e-06	2.77e-05	3.00e-01
READ	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	4.24e-01	8.59e-02	8.19e+00	2.72e-16	3.65e-15	3.38e-01
READ	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.87e-01	4.34e-02	8.49e+00	2.15e-17	4.34e-16	4.44e-01
READ	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.42e-01	6.20e-02	8.30e+00	1.04e-16	1.49e-15	2.80e-01
READ	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.81e-01	1.07e-01	7.71e+00	1.29e-14	1.42e-13	3.73e-01
READ	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.64e-01	1.53e-01	7.76e+00	8.24e-15	9.23e-14	3.12e-01
READ	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.95e-01	2.07e-01	5.01e+00	5.33e-07	3.22e-06	1.88e-01
GBM	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.64e-01	1.01e-01	6.64e+00	3.16e-11	4.42e-10	4.63e-01
GBM	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.79e-01	2.99e-02	6.75e+00	1.48e-11	2.64e-10	5.49e-01
GBM	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	5.07e-01	4.35e-02	6.54e+00	6.08e-11	7.90e-10	4.63e-01
GBM	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	4.17e-01	9.56e-02	3.61e+00	3.05e-04	1.37e-03	3.21e-01
GBM	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.32e-01	4.96e-02	6.75e+00	1.48e-11	2.64e-10	4.83e-01
GBM	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.87e-01	5.92e-02	6.75e+00	1.48e-11	2.64e-10	3.27e-01
GBM	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.91e-01	3.40e-02	6.75e+00	1.48e-11	2.64e-10	4.57e-01
GBM	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.77e-01	5.88e-02	6.75e+00	1.48e-11	2.64e-10	4.19e-01
GBM	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	4.19e-01	8.05e-02	6.44e+00	1.16e-10	1.42e-09	3.38e-01
GBM	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	5.40e-01	3.08e-01	4.64e+00	3.50e-06	2.20e-05	2.33e-01
ESCA	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.97e-01	2.95e-01	5.10e+00	3.42e-07	2.43e-06	3.01e-01
ESCA	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.75e-01	3.97e-02	7.47e+00	7.78e-14	1.11e-12	5.35e-01
ESCA	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	5.36e-01	1.95e-01	5.25e+00	1.54e-07	1.13e-06	3.41e-01
ESCA	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	4.44e-01	1.28e-01	4.44e+00	8.95e-06	5.55e-05	3.16e-01
ESCA	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.88e-01	6.56e-02	7.41e+00	1.25e-13	1.67e-12	4.23e-01
ESCA	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.67e-01	7.97e-02	7.46e+00	8.68e-14	1.21e-12	2.87e-01
ESCA	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.81e-01	7.11e-02	7.37e+00	1.67e-13	2.16e-12	4.10e-01
ESCA	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.54e-01	1.12e-01	7.09e+00	1.34e-12	1.50e-11	3.42e-01
ESCA	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.92e-01	1.56e-01	5.98e+00	2.21e-09	1.87e-08	2.37e-01
LAML	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	7.32e-01	5.89e-01	2.18e+00	2.91e-02	4.06e-02	1.43e-01
LAML	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	6.02e-01	1.30e-01	7.80e+00	6.04e-15	3.54e-14	4.72e-01
LAML	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.63e-01	4.03e-02	1.02e+01	3.31e-24	2.70e-22	5.22e-01
LAML	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	7.17e-01	5.32e-01	2.48e+00	1.32e-02	2.63e-02	1.85e-01
LAML	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	4.00e-01	8.73e-02	9.71e+00	2.80e-22	3.04e-21	3.12e-01
LAML	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.44e-01	7.00e-02	9.70e+00	3.02e-22	3.25e-21	4.74e-01
LAML	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.31e-01	6.62e-02	9.84e+00	7.40e-23	9.93e-22	2.65e-01
LAML	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	5.13e-01	1.54e-01	8.97e+00	2.99e-19	2.32e-18	3.58e-01
LAML	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	5.20e-01	2.72e-01	6.20e+00	5.56e-10	2.46e-09	2.48e-01
LAML	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	6.11e-01	4.59e-01	2.12e+00	3.43e-02	4.35e-02	1.52e-01
THYM	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.76e-01	2.95e-01	7.94e+00	2.08e-15	1.33e-14	2.81e-01
THYM	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.96e-01	1.20e-01	6.66e+00	2.74e-11	1.30e-10	3.76e-01
THYM	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.38e-01	2.62e-02	9.40e+00	5.48e-21	1.00e-19	5.12e-01
THYM	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	4.89e-01	1.60e-01	7.83e+00	4.87e-15	3.03e-14	3.28e-01
THYM	cg10076009	chrX:129522748	CGI:chrX:129522874-129523429	promoter,gene body	3.82e-01	1.07e-01	8.25e+00	1.58e-16	1.14e-15	2.74e-01
THYM	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.46e-01	5.58e-02	9.40e+00	5.48e-21	1.00e-19	4.90e-01
THYM	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	2.85e-01	7.28e-02	9.40e+00	5.48e-21	1.00e-19	2.12e-01
THYM	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.54e-01	4.34e-02	9.39e+00	5.77e-21	1.00e-19	4.10e-01
THYM	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.39e-01	9.51e-02	8.80e+00	1.39e-18	1.24e-17	3.44e-01
THYM	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	4.76e-01	1.69e-01	3.96e+00	7.57e-05	2.32e-04	3.07e-01
MESO	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	5.13e-01	1.87e-01	5.30e+00	1.17e-07	1.07e-06	3.26e-01
MESO	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	4.24e-01	3.14e-02	6.06e+00	1.36e-09	2.54e-08	3.93e-01
MESO	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	4.32e-01	8.80e-02	5.42e+00	5.87e-08	5.61e-07	3.44e-01
MESO	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.14e-01	6.77e-02	6.06e+00	1.36e-09	2.54e-08	3.47e-01
MESO	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	2.31e-01	8.24e-02	6.04e+00	1.57e-09	2.60e-08	1.49e-01
MESO	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.28e-01	5.05e-02	6.06e+00	1.36e-09	2.54e-08	3.77e-01
MESO	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.89e-01	7.06e-02	6.06e+00	1.36e-09	2.54e-08	3.18e-01
MESO	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.66e-01	1.58e-01	2.99e+00	2.81e-03	1.20e-02	2.08e-01
UVM	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	4.13e-01	6.37e-02	7.13e+00	9.80e-13	1.07e-11	3.49e-01
UVM	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	3.69e-01	2.73e-02	7.40e+00	1.41e-13	2.21e-12	3.41e-01
UVM	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	3.11e-01	3.63e-02	6.84e+00	7.79e-12	7.15e-11	2.74e-01
UVM	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.05e-01	5.26e-02	7.63e+00	2.39e-14	9.97e-13	3.52e-01
UVM	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	1.75e-01	6.78e-02	5.76e+00	8.61e-09	5.38e-08	1.07e-01
UVM	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.41e-01	3.71e-02	7.64e+00	2.21e-14	9.97e-13	3.04e-01
UVM	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.23e-01	4.90e-02	7.64e+00	2.21e-14	9.97e-13	2.74e-01
UVM	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.19e-01	1.06e-01	4.80e+00	1.62e-06	7.32e-06	2.13e-01
UVM	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	4.36e-01	3.01e-01	2.91e+00	3.56e-03	9.52e-03	1.35e-01
ACC	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.06e-01	7.04e-02	7.39e+00	1.47e-13	3.50e-12	3.35e-01
ACC	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.18e-01	4.90e-02	7.47e+00	8.02e-14	2.68e-12	3.69e-01
ACC	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	4.27e-01	6.37e-02	7.01e+00	2.42e-12	3.88e-11	3.63e-01
ACC	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	4.76e-01	1.69e-01	5.84e+00	5.11e-09	5.27e-08	3.07e-01
ACC	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	4.30e-01	2.84e-02	7.33e+00	2.31e-13	4.98e-12	4.01e-01
ACC	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	2.39e-01	5.53e-02	7.24e+00	4.52e-13	8.72e-12	1.84e-01
ACC	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.31e-01	1.53e-01	4.72e+00	2.37e-06	1.92e-05	1.78e-01
ACC	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	3.67e-01	1.31e-01	5.31e+00	1.09e-07	9.92e-07	2.36e-01
ACC	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	2.53e-01	1.23e-01	3.85e+00	1.20e-04	8.03e-04	1.29e-01
KICH	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	3.65e-01	1.03e-01	5.73e+00	9.97e-09	1.15e-07	2.62e-01
KICH	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	2.62e-01	1.00e-01	4.78e+00	1.75e-06	1.55e-05	1.62e-01
KICH	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	2.93e-01	3.23e-02	6.57e+00	4.87e-11	1.88e-09	2.61e-01
KICH	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	2.12e-01	5.30e-02	5.97e+00	2.34e-09	3.06e-08	1.59e-01
KICH	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	3.16e-01	5.14e-02	6.57e+00	4.87e-11	1.88e-09	2.64e-01
KICH	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	1.64e-01	6.20e-02	6.20e+00	5.65e-10	8.63e-09	1.02e-01
KICH	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	3.40e-01	4.81e-02	6.56e+00	5.33e-11	1.88e-09	2.92e-01
KICH	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	2.99e-01	6.94e-02	6.53e+00	6.38e-11	1.88e-09	2.29e-01
KICH	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	2.59e-01	9.38e-02	5.69e+00	1.26e-08	1.43e-07	1.65e-01
DLBC	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	7.81e-01	6.17e-01	2.26e+00	2.41e-02	3.84e-02	1.64e-01
DLBC	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	6.87e-01	4.37e-01	2.01e+00	4.47e-02	4.83e-02	2.49e-01
DLBC	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	7.68e-01	5.63e-01	2.28e+00	2.28e-02	3.74e-02	2.05e-01
DLBC	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	6.00e-01	3.27e-01	2.96e+00	3.09e-03	9.28e-03	2.73e-01
DLBC	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	4.74e-01	3.28e-01	2.21e+00	2.68e-02	4.02e-02	1.47e-01
DLBC	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	5.80e-01	3.80e-01	2.23e+00	2.54e-02	3.93e-02	2.00e-01
DLBC	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	6.09e-01	4.34e-01	2.07e+00	3.85e-02	4.62e-02	1.75e-01
CHOL	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	7.16e-01	3.29e-01	3.76e+00	1.72e-04	8.33e-04	3.87e-01
CHOL	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	5.64e-01	3.47e-02	5.09e+00	3.51e-07	4.92e-06	5.29e-01
CHOL	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	6.73e-01	2.39e-01	3.98e+00	6.91e-05	3.67e-04	4.34e-01
CHOL	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	5.25e-01	6.05e-02	5.09e+00	3.51e-07	4.92e-06	4.64e-01
CHOL	cg17420696	chrX:129523115	CGI:chrX:129522874-129523429	promoter,gene body	3.82e-01	8.60e-02	4.90e+00	9.45e-07	9.05e-06	2.96e-01
CHOL	cg06675660	chrX:129523387	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	5.17e-01	5.12e-02	5.09e+00	3.51e-07	4.92e-06	4.66e-01
CHOL	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	5.07e-01	8.54e-02	5.06e+00	4.15e-07	5.14e-06	4.21e-01
CHOL	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	5.19e-01	2.07e-01	3.12e+00	1.81e-03	5.90e-03	3.12e-01

Differentially expressed CpG sites between male tumor and male normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
KIRC	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	1.53e-01	4.61e-02	5.57e+00	2.53e-08	1.56e-07	1.07e-01
THCA	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	3.07e-01	2.05e-01	1.99e+00	4.69e-02	4.79e-02	1.02e-01
HNSC	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	3.12e-01	1.43e-01	4.02e+00	5.85e-05	1.65e-04	1.70e-01
HNSC	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	1.78e-01	4.49e-02	3.65e+00	2.60e-04	5.79e-04	1.33e-01
COAD	cg08617833	chrX:129523720	CGI:chrX:129522874-129523429	promoter	4.97e-01	2.54e-01	2.71e+00	6.74e-03	1.05e-02	2.43e-01
COAD	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	3.82e-01	8.13e-02	2.45e+00	1.43e-02	1.90e-02	3.01e-01
COAD	cg03460558	chrX:129523496	CGI:chrX:129522874-129523429	UTR,promoter,exon,gene body	2.22e-01	1.00e-01	2.27e+00	2.29e-02	2.75e-02	1.22e-01
COAD	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	2.53e-01	9.27e-02	1.96e+00	5.00e-02	5.00e-02	1.60e-01
KIRP	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	3.92e-01	2.28e-01	2.88e+00	3.92e-03	5.80e-03	1.63e-01
CHOL	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	6.32e-01	2.49e-01	2.51e+00	1.22e-02	2.39e-02	3.83e-01

Differentially expressed CpG sites between female tumor and female normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	3.74e-01	6.03e-01	-8.05e+00	8.12e-16	3.15e-15	-2.29e-01
BRCA	cg26010110	chrX:129523722	CGI:chrX:129522874-129523429	promoter	6.03e-01	5.00e-01	6.55e+00	5.65e-11	1.51e-10	1.03e-01
BRCA	cg24447042	chrX:129523916	CGI:chrX:129522874-129523429	promoter	6.27e-01	3.99e-01	1.25e+01	4.44e-36	1.56e-34	2.28e-01
THCA	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.86e-01	5.99e-01	-3.21e+00	1.33e-03	2.78e-03	-1.13e-01
HNSC	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	4.12e-01	6.59e-01	-2.94e+00	3.27e-03	1.13e-02	-2.47e-01
COAD	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	3.84e-01	6.21e-01	-2.85e+00	4.42e-03	8.69e-03	-2.37e-01
BLCA	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	3.13e-01	6.22e-01	-2.59e+00	9.55e-03	1.69e-02	-3.10e-01
BLCA	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	4.97e-01	6.11e-01	-2.44e+00	1.47e-02	2.22e-02	-1.14e-01
BLCA	cg18959966	chrX:129523750	CGI:chrX:129522874-129523429	promoter	3.81e-01	4.90e-01	-2.80e+00	5.16e-03	1.16e-02	-1.09e-01
LIHC	cg27353825	chrX:129522943	CGI:chrX:129522874-129523429	promoter,gene body	2.56e-01	5.48e-01	-3.61e+00	3.02e-04	8.94e-04	-2.92e-01
LIHC	cg12935118	chrX:129523061	CGI:chrX:129522874-129523429	promoter,gene body	4.09e-01	5.67e-01	-3.16e+00	1.57e-03	3.22e-03	-1.59e-01
LIHC	cg04596655	chrX:129522791	CGI:chrX:129522874-129523429	promoter,gene body	4.06e-01	5.46e-01	-3.85e+00	1.20e-04	4.42e-04	-1.39e-01

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Exon skipping events with PSI in TCGA for SMARCA1

∗Please access ExonSkipDB for exon skipping annotation.

Landscape of exon skipping events across multiple cancer types.

Differentially expressed exon skipping events between male tumor and female tumor patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between male tumor and male normal patients.

Cancer Type	Exon Skipping	ave.female_T	ave.female_N	wilcoxon.w	wilcoxon.p	padj	dPSI
KICH	exon_skip_516641	7.08e-01	5.97e-01	3.18e+00	1.50e-03	6.45e-03	1.11e-01

Differentially expressed exon skipping events between female tumor and female normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

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RNA A-to-I editing events in TCGA for SMARCA1

∗Please access CAeditome for RNA editing annotation.

Differentially expressed RNA editing events between male tumor and female tumor patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between male tumor and male normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between female tumor and female normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Protein coding RNA editing(s).

Editing Position

Variant Type

Gene Symbol

Transcript ID

NTchange

AAchange

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Sex-biased TF-Gene network for SMARCA1

TFs related to SMARCA1.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type	TF	Target Gene	Male Edge Score	Male Edge Threshold	Female Edge Score	Female Edge Threshold	Type
ACC	ZNF100	SMARCA1	3.09e+00	5.74e-03	4.05e+00	9.84e-01	Female-biased
ACC	ZNF460	SMARCA1	3.08e+00	7.13e-03	3.99e+00	9.81e-01	Female-biased
BRCA	PRDM6	SMARCA1	4.52e+00	9.93e-01	2.17e+00	3.17e-04	Male-biased
BRCA	ZNF225	SMARCA1	4.57e+00	9.93e-01	2.42e+00	6.27e-04	Male-biased
BRCA	ZNF443	SMARCA1	4.11e+00	9.85e-01	1.82e+00	3.80e-04	Male-biased
DLBC	CUX2	SMARCA1	5.71e+00	8.21e-03	6.67e+00	9.91e-01	Female-biased
DLBC	FOXG1	SMARCA1	2.27e+00	6.24e-04	3.95e+00	9.83e-01	Female-biased
DLBC	HESX1	SMARCA1	3.54e+00	2.15e-03	4.87e+00	9.94e-01	Female-biased
DLBC	ZNF248	SMARCA1	3.53e+00	6.30e-03	4.56e+00	9.88e-01	Female-biased
DLBC	ZNF250	SMARCA1	3.42e+00	3.62e-03	4.60e+00	9.91e-01	Female-biased
DLBC	ZNF584	SMARCA1	2.88e+00	7.31e-04	4.53e+00	9.93e-01	Female-biased

SMARCA1 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for SMARCA1

RBPs related to ES in SMARCA1.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type	RBP	Target ES	Male Edge Score	Male Edge Threshold	Female Edge Score	Female Edge Threshold	Type
ACC	SFPQ	exon_skip_516645	1.02e+01	9.89e-01	9.76e+00	9.44e-03	Male-biased
LIHC	ZNF638	exon_skip_516644	1.32e+01	9.92e-01	1.28e+01	7.34e-03	Male-biased
LUSC	ZNF638	exon_skip_516644	1.28e+01	3.60e-03	1.32e+01	9.96e-01	Female-biased
ESCA	ZNF638	exon_skip_516644	1.24e+01	9.74e-03	1.29e+01	9.90e-01	Female-biased
THCA	ZNF638	exon_skip_516644	1.31e+01	9.99e-01	1.26e+01	6.41e-04	Male-biased
PCPG	ELAVL2	exon_skip_516637	9.65e+00	9.92e-01	9.28e+00	5.95e-03	Male-biased
MESO	SFPQ	exon_skip_516645	9.69e+00	8.44e-03	1.01e+01	9.90e-01	Female-biased
MESO	SRSF2	exon_skip_516639	9.13e+00	9.88e-01	8.76e+00	8.24e-03	Male-biased
MESO	ZNF638	exon_skip_516644	1.28e+01	1.33e-03	1.33e+01	9.98e-01	Female-biased
LGG	ELAVL2	exon_skip_516637	9.35e+00	9.87e-01	9.02e+00	1.04e-02	Male-biased
PAAD	IGF2BP2	exon_skip_516645	7.53e+00	9.83e-01	7.20e+00	6.93e-03	Male-biased
PAAD	IGF2BP3	exon_skip_516645	7.50e+00	9.83e-01	7.17e+00	7.02e-03	Male-biased
PAAD	SFPQ	exon_skip_516645	1.02e+01	9.88e-01	9.90e+00	1.08e-02	Male-biased
PAAD	ZNF638	exon_skip_516644	1.25e+01	7.44e-04	1.30e+01	9.99e-01	Female-biased
KICH	IGF2BP2	exon_skip_516645	7.13e+00	6.73e-03	7.48e+00	9.83e-01	Female-biased
KICH	IGF2BP3	exon_skip_516645	7.11e+00	6.72e-03	7.46e+00	9.83e-01	Female-biased
KICH	SFPQ	exon_skip_516645	9.71e+00	4.30e-03	1.01e+01	9.94e-01	Female-biased
HNSC	ELAVL2	exon_skip_516637	9.23e+00	1.18e-02	9.55e+00	9.86e-01	Female-biased
SARC	SFPQ	exon_skip_516645	1.00e+01	9.94e-01	9.58e+00	4.22e-03	Male-biased

SMARCA1 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

Sex-biased CeRNA regulation of gene.

Gene ID	ceRNA(lncRNA-miRNA-mRNA)	Group	Cancer Type
ENSG00000102038	AL122035.2,hsa-mir-203a,SMARCA1	Male-specific ceRNA	TCGA-BLCA
ENSG00000102038	LOH12CR2,hsa-mir-203a,SMARCA1	Male-specific ceRNA	TCGA-BLCA
ENSG00000102038	AC022364.1,hsa-mir-203a,SMARCA1	Male-specific ceRNA	TCGA-BLCA

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Sex-biased eQTL regulation of gene

Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

eQTL

Description

Male-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Female-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased eQTL regulation.

SNP ID

SNP Info

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Sex-biased Gene in Cancer

Cancer Type

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Sex-biased eQTM regulation of gene

Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).

eQTM	Description
	Gene ID: ENSG00000102038
	CpG Site: cg19250658
	Position to Gene: gene
	Male Effect: -0.410703361978004
	Female Effect: -
	Gene ID: ENSG00000102038
	CpG Site: cg08617833
	Position to Gene: promoter
	Male Effect: -0.0712107329173518
	Female Effect: -
	Gene ID: ENSG00000102038
	CpG Site: cg08617833
	Position to Gene: promoter
	Male Effect: -0.0776202132415352
	Female Effect: -
	Gene ID: ENSG00000102038
	CpG Site: cg08617833
	Position to Gene: promoter
	Male Effect: -0.0360681341931414
	Female Effect: -

Male-specific eQTM regulation.

CpG Site	CpG Postion	Position to Gene	Effect Score	FDR	Cor.r	Cor.Pvalue	Cancer Type
cg19250658	chrX:129520479	gene	-0.410703361978004	1.41387675825769e-07	-0.43210417028139536	5.2195695834118714e-11	LUAD
cg08617833	chrX:129523720	promoter	-0.0712107329173518	4.65058672329952e-06	-0.36690477405827965	2.048209820737154e-08	STAD
cg08617833	chrX:129523720	promoter	-0.0776202132415352	1.8882014952692e-09	-0.3963811717238867	1.9988947457682778e-12	SKCM
cg08617833	chrX:129523720	promoter	-0.0360681341931414	8.27022823548489e-06	-0.3064801865406698	4.6952745596583905e-08	BLCA

Female-specific eQTM regulation.

CpG Site

CpG Postion

Position to Gene

Effect Score

FDR

Cor.r

Cor.Pvalue

Cancer Type

Opposite sex-biased eQTM regulation.

CpG Site

CpG Postion

CpG Island

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Male Cor

Male P-value

Female Cor

Female P-value

Sex-biased Coding Gene

Cancer Type

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Sex-biased sQTL regulation of gene

Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTL

Description

Male-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Female-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Male Effect

Male FDR

Female Effect

Female FDR

Cancer Type

Top

Sex-biased sQTM regulation of gene

Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTM

Description

Male-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Female-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Opposite sex-biased sQTM regulation.

EX ID

EX Info

Skipped Exon

CPG Site

CPG Position

CPG Island

Position to EX Events

Male Effect

Male FDR

Female Effect

Female FDR

Male Correlation

Male P-value

Female Correlation

Female P-value

ORF_anno

Cancer Type

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Related disease information of SMARCA1

Diseases associated with this gene (DisGeNET).

Gene ID	Gene Symbol	Disease ID	Disease Name	Number of PMID	Source
ENSG00000102038	SMARCA1	C0033578	Prostatic Neoplasms	1	CTD_human
ENSG00000102038	SMARCA1	C0376358	Malignant neoplasm of prostate	1	CTD_human

	Gene summary
	Gene structure and Gene expression level
	Sex-biased somatic mutation
	DNA methylation with beta values in gene
	Exon skipping events with PSI in TCGA
	RNA A-to-I editing events in TCGA
	Sex-biased TF-Gene network of gene
	Sex-biased RBP-ES network of gene
	Sex-biased CeRNA regulation of gene
	Sex-biased eQTL regulation of gene
	Sex-biased eQTM regulation of gene
	Sex-biased sQTL regulation of gene
	Sex-biased sQTM regulation of gene
	Related disease information of gene