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Gene: ENSG00000101888 |
Summary for NXT2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000101888 | Gene symbol | NXT2 |
| Gene name | nuclear transport factor 2 like export factor 2 | |
| HGNC | 18151 | |
| Entrez ID | 55916 | |
| Gene type | protein_coding | |
| Synonyms | NXT2|P15-2 | |
| UniProtAcc | Q9NPJ8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for NXT2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| NXT2 | 1.29e+03 | 1.14e+00 | 2.81e-01 | 4.04e+00 | 5.24e-05 | 5.40e-04 | STAD |
Top |
Sex-biased somatic mutation for NXT2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for NXT2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.98e-01 | 2.67e-02 | 5.14e+00 | 2.77e-07 | 1.16e-05 | 2.72e-01 |
| BRCA | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.47e-01 | 2.61e-02 | 5.13e+00 | 2.90e-07 | 1.16e-05 | 2.21e-01 |
| BRCA | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 6.32e-01 | 7.73e-01 | -3.14e+00 | 1.69e-03 | 1.25e-02 | -1.41e-01 |
| LGG | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.88e-01 | 2.87e-02 | 1.98e+01 | 6.50e-87 | 3.34e-85 | 2.59e-01 |
| LGG | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.46e-01 | 2.67e-02 | 1.84e+01 | 1.71e-75 | 3.10e-74 | 1.19e-01 |
| LGG | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 6.84e-01 | 8.08e-01 | -9.51e+00 | 1.94e-21 | 1.36e-20 | -1.24e-01 |
| LGG | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 3.35e-01 | 7.20e-02 | 1.97e+01 | 3.76e-86 | 1.52e-84 | 2.63e-01 |
| LUSC | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.71e-01 | 2.91e-02 | 1.44e+01 | 4.40e-47 | 1.48e-45 | 2.42e-01 |
| LUSC | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.35e-01 | 2.50e-02 | 1.45e+01 | 1.31e-47 | 1.26e-45 | 2.10e-01 |
| LUSC | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 1.75e-01 | 6.19e-02 | 1.31e+01 | 3.73e-39 | 5.90e-38 | 1.13e-01 |
| SKCM | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.33e-01 | 2.80e-02 | 1.80e+01 | 1.02e-72 | 4.02e-71 | 2.05e-01 |
| SKCM | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.66e-01 | 2.77e-02 | 1.75e+01 | 6.00e-69 | 1.50e-67 | 1.38e-01 |
| SKCM | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.13e-01 | 6.26e-02 | 1.59e+01 | 3.03e-57 | 5.10e-56 | 1.51e-01 |
| STAD | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.74e-01 | 2.69e-02 | 1.52e+01 | 6.81e-52 | 4.96e-50 | 2.47e-01 |
| STAD | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.63e-01 | 2.67e-02 | 1.51e+01 | 1.16e-51 | 5.90e-50 | 2.36e-01 |
| STAD | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 1.85e-01 | 6.93e-02 | 1.23e+01 | 7.54e-35 | 1.31e-33 | 1.16e-01 |
| LIHC | cg26144456 | chrX:109535777 | CGI:chrX:109536825-109537184 | promoter | 7.71e-01 | 8.78e-01 | -6.27e+00 | 3.50e-10 | 6.32e-09 | -1.08e-01 |
| SARC | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.22e-01 | 2.89e-02 | 1.29e+01 | 7.09e-38 | 2.90e-36 | 1.93e-01 |
| SARC | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.62e-01 | 3.01e-02 | 1.16e+01 | 3.92e-31 | 1.08e-29 | 1.31e-01 |
| SARC | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.46e-01 | 8.64e-02 | 9.07e+00 | 1.15e-19 | 1.56e-18 | 1.59e-01 |
| PCPG | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.66e-01 | 2.98e-02 | 1.14e+01 | 5.88e-30 | 1.20e-28 | 1.37e-01 |
| PCPG | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.10e-01 | 7.46e-02 | 9.66e+00 | 4.61e-22 | 5.01e-21 | 1.35e-01 |
| PAAD | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.02e-01 | 3.08e-02 | 1.15e+01 | 2.03e-30 | 1.01e-28 | 2.72e-01 |
| PAAD | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.90e-01 | 3.10e-02 | 1.13e+01 | 1.51e-29 | 4.54e-28 | 2.59e-01 |
| PAAD | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.17e-01 | 8.37e-02 | 1.06e+01 | 4.19e-26 | 8.45e-25 | 1.34e-01 |
| READ | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.28e-01 | 2.43e-02 | 8.47e+00 | 2.43e-17 | 4.41e-16 | 3.04e-01 |
| READ | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.34e-01 | 2.33e-02 | 8.46e+00 | 2.75e-17 | 4.73e-16 | 3.11e-01 |
| GBM | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.25e-01 | 2.59e-02 | 6.75e+00 | 1.48e-11 | 2.64e-10 | 2.99e-01 |
| GBM | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.29e-01 | 2.42e-02 | 6.75e+00 | 1.48e-11 | 2.64e-10 | 2.05e-01 |
| GBM | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 3.16e-01 | 6.39e-02 | 6.46e+00 | 1.06e-10 | 1.31e-09 | 2.52e-01 |
| ESCA | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.69e-01 | 3.22e-02 | 7.57e+00 | 3.73e-14 | 6.84e-13 | 2.37e-01 |
| ESCA | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.06e-01 | 3.14e-02 | 7.57e+00 | 3.87e-14 | 6.84e-13 | 1.75e-01 |
| LAML | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.31e-01 | 3.48e-02 | 9.98e+00 | 1.85e-23 | 3.90e-22 | 2.96e-01 |
| LAML | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.58e-01 | 3.00e-02 | 9.95e+00 | 2.52e-23 | 4.59e-22 | 3.28e-01 |
| LAML | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 3.41e-01 | 6.07e-02 | 1.01e+01 | 6.21e-24 | 2.74e-22 | 2.80e-01 |
| THYM | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.31e-01 | 2.57e-02 | 9.39e+00 | 6.07e-21 | 1.00e-19 | 2.06e-01 |
| THYM | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.42e-01 | 2.19e-02 | 9.40e+00 | 5.48e-21 | 1.00e-19 | 2.20e-01 |
| THYM | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.53e-01 | 8.52e-02 | 8.16e+00 | 3.35e-16 | 2.31e-15 | 1.68e-01 |
| MESO | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.88e-01 | 3.00e-02 | 6.06e+00 | 1.36e-09 | 2.54e-08 | 2.58e-01 |
| MESO | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.21e-01 | 2.77e-02 | 6.06e+00 | 1.36e-09 | 2.54e-08 | 1.93e-01 |
| MESO | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 6.32e-01 | 7.64e-01 | -2.82e+00 | 4.85e-03 | 1.80e-02 | -1.32e-01 |
| MESO | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.11e-01 | 1.03e-01 | 4.71e+00 | 2.53e-06 | 1.93e-05 | 1.08e-01 |
| UVM | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.44e-01 | 2.72e-02 | 7.53e+00 | 5.04e-14 | 1.15e-12 | 1.17e-01 |
| UVM | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.81e-01 | 2.28e-02 | 7.12e+00 | 1.05e-12 | 1.14e-11 | 1.59e-01 |
| UVM | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.13e-01 | 7.64e-02 | 6.11e+00 | 9.66e-10 | 6.92e-09 | 1.37e-01 |
| ACC | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 5.24e-01 | 6.59e-01 | -2.27e+00 | 2.33e-02 | 3.77e-02 | -1.35e-01 |
| ACC | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.01e-01 | 2.43e-02 | 7.14e+00 | 9.43e-13 | 1.64e-11 | 1.77e-01 |
| ACC | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.42e-01 | 6.83e-02 | 6.39e+00 | 1.71e-10 | 2.05e-09 | 1.73e-01 |
| ACC | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.42e-01 | 2.89e-02 | 7.45e+00 | 9.34e-14 | 2.69e-12 | 2.13e-01 |
| KICH | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 1.38e-01 | 2.75e-02 | 6.40e+00 | 1.55e-10 | 3.04e-09 | 1.10e-01 |
| KICH | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 8.12e-01 | 6.23e-01 | 2.08e+00 | 3.79e-02 | 4.59e-02 | 1.89e-01 |
| KICH | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 1.71e-01 | 6.14e-02 | 5.80e+00 | 6.71e-09 | 7.96e-08 | 1.10e-01 |
| DLBC | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.61e-01 | 2.81e-02 | 5.92e+00 | 3.26e-09 | 5.31e-08 | 2.33e-01 |
| DLBC | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.58e-01 | 2.60e-02 | 5.90e+00 | 3.70e-09 | 5.58e-08 | 2.32e-01 |
| CHOL | cg26376518 | chrX:109536898 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.57e-01 | 3.20e-02 | 4.90e+00 | 9.45e-07 | 9.05e-06 | 3.25e-01 |
| CHOL | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.22e-01 | 4.09e-02 | 4.84e+00 | 1.30e-06 | 1.17e-05 | 2.81e-01 |
| CHOL | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 2.65e-01 | 7.94e-02 | 4.36e+00 | 1.29e-05 | 8.44e-05 | 1.86e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 7.58e-01 | 8.72e-01 | -2.06e+00 | 3.94e-02 | 4.12e-02 | -1.14e-01 |
| LUSC | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 6.73e-01 | 8.76e-01 | -3.16e+00 | 1.57e-03 | 3.54e-03 | -2.04e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg13257485 | chrX:109535625 | CGI:chrX:109536825-109537184 | promoter | 6.21e-01 | 7.86e-01 | -2.47e+00 | 1.37e-02 | 2.21e-02 | -1.65e-01 |
| COAD | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 3.16e-01 | 4.41e-01 | -2.26e+00 | 2.35e-02 | 2.92e-02 | -1.25e-01 |
| COAD | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 1.30e-01 | 3.25e-01 | -4.53e+00 | 5.92e-06 | 3.13e-04 | -1.95e-01 |
| BLCA | cg18240390 | chrX:109537149 | CGI:chrX:109536825-109537184 | UTR,promoter,exon,gene body | 2.13e-01 | 3.60e-01 | -3.34e+00 | 8.47e-04 | 4.48e-03 | -1.47e-01 |
| BLCA | cg26144456 | chrX:109535777 | CGI:chrX:109536825-109537184 | promoter | 8.10e-01 | 9.23e-01 | -2.41e+00 | 1.60e-02 | 2.35e-02 | -1.12e-01 |
| BLCA | cg24139895 | chrX:109537448 | CGI:chrX:109536825-109537184 | promoter,gene body | 1.59e-01 | 2.65e-01 | -3.68e+00 | 2.31e-04 | 2.98e-03 | -1.07e-01 |
| LIHC | cg26144456 | chrX:109535777 | CGI:chrX:109536825-109537184 | promoter | 7.71e-01 | 9.17e-01 | -2.28e+00 | 2.24e-02 | 2.64e-02 | -1.47e-01 |
Top |
Exon skipping events with PSI in TCGA for NXT2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for NXT2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for NXT2 |
| TFs related to NXT2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | ZNF418 | NXT2 | 4.78e+00 | 9.82e-01 | 4.06e+00 | 1.34e-02 | Male-biased |
| DLBC | DUX4 | NXT2 | 4.75e+00 | 9.89e-01 | 3.76e+00 | 5.94e-03 | Male-biased |
| DLBC | HNF1A | NXT2 | 4.30e+00 | 9.88e-01 | 3.01e+00 | 1.92e-03 | Male-biased |
| DLBC | HOXB7 | NXT2 | 4.38e+00 | 9.89e-01 | 3.19e+00 | 2.76e-03 | Male-biased |
| DLBC | HSF5 | NXT2 | 5.15e+00 | 9.83e-01 | 4.38e+00 | 1.43e-02 | Male-biased |
| DLBC | LHX3 | NXT2 | 4.18e+00 | 9.87e-01 | 2.83e+00 | 1.47e-03 | Male-biased |
| DLBC | LHX8 | NXT2 | 5.79e+00 | 9.93e-01 | 4.77e+00 | 5.66e-03 | Male-biased |
| DLBC | MEOX2 | NXT2 | 4.20e+00 | 9.87e-01 | 2.86e+00 | 1.57e-03 | Male-biased |
| DLBC | NOBOX | NXT2 | 6.73e+00 | 9.80e-01 | 6.03e+00 | 1.96e-02 | Male-biased |
| DLBC | PBX4 | NXT2 | 4.63e+00 | 9.91e-01 | 3.52e+00 | 3.81e-03 | Male-biased |
| DLBC | POU2F2 | NXT2 | 4.13e+00 | 9.86e-01 | 2.82e+00 | 1.73e-03 | Male-biased |
| DLBC | POU5F1 | NXT2 | 4.19e+00 | 9.87e-01 | 2.89e+00 | 1.81e-03 | Male-biased |
| DLBC | SOX2 | NXT2 | 4.19e+00 | 9.86e-01 | 3.00e+00 | 2.74e-03 | Male-biased |
| DLBC | SOX4 | NXT2 | 4.16e+00 | 9.86e-01 | 2.86e+00 | 1.82e-03 | Male-biased |
| DLBC | STAT5B | NXT2 | 4.03e+00 | 9.82e-01 | 2.88e+00 | 3.12e-03 | Male-biased |
| DLBC | ZSCAN9 | NXT2 | 4.06e+00 | 9.82e-01 | 2.92e+00 | 3.28e-03 | Male-biased |
| LAML | ZNF25 | NXT2 | 3.48e+00 | 8.85e-03 | 4.41e+00 | 9.81e-01 | Female-biased |
| LAML | ZNF418 | NXT2 | 3.48e+00 | 2.25e-03 | 4.76e+00 | 9.92e-01 | Female-biased |
| PCPG | DUX4 | NXT2 | 5.02e+00 | 9.93e-01 | 4.03e+00 | 4.26e-03 | Male-biased |
| PCPG | FOXG1 | NXT2 | 4.46e+00 | 9.92e-01 | 2.77e+00 | 1.14e-04 | Male-biased |
| PCPG | FOXJ3 | NXT2 | 4.36e+00 | 9.90e-01 | 3.05e+00 | 8.80e-04 | Male-biased |
| PCPG | HNF1A | NXT2 | 4.79e+00 | 9.93e-01 | 3.64e+00 | 2.04e-03 | Male-biased |
| PCPG | HOXB7 | NXT2 | 4.78e+00 | 9.93e-01 | 3.64e+00 | 2.19e-03 | Male-biased |
| PCPG | HSF5 | NXT2 | 5.39e+00 | 9.88e-01 | 4.60e+00 | 1.05e-02 | Male-biased |
| PCPG | HSFY1 | NXT2 | 5.03e+00 | 9.86e-01 | 4.24e+00 | 1.11e-02 | Male-biased |
| PCPG | IRF1 | NXT2 | 4.41e+00 | 9.90e-01 | 3.26e+00 | 1.98e-03 | Male-biased |
| PCPG | LHX3 | NXT2 | 4.75e+00 | 9.95e-01 | 3.35e+00 | 5.77e-04 | Male-biased |
| PCPG | LHX8 | NXT2 | 6.04e+00 | 9.92e-01 | 5.17e+00 | 7.42e-03 | Male-biased |
| PCPG | MEOX2 | NXT2 | 4.71e+00 | 9.93e-01 | 3.49e+00 | 1.46e-03 | Male-biased |
| PCPG | PBX4 | NXT2 | 5.09e+00 | 9.95e-01 | 3.95e+00 | 2.15e-03 | Male-biased |
| PCPG | POU2F2 | NXT2 | 4.76e+00 | 9.94e-01 | 3.42e+00 | 8.18e-04 | Male-biased |
| PCPG | POU5F1 | NXT2 | 4.67e+00 | 9.94e-01 | 3.37e+00 | 9.89e-04 | Male-biased |
| PCPG | PRDM1 | NXT2 | 4.32e+00 | 9.87e-01 | 3.26e+00 | 3.05e-03 | Male-biased |
| PCPG | SOX2 | NXT2 | 4.79e+00 | 9.94e-01 | 3.55e+00 | 1.36e-03 | Male-biased |
| PCPG | SOX4 | NXT2 | 4.61e+00 | 9.92e-01 | 3.44e+00 | 1.89e-03 | Male-biased |
| PCPG | STAT2 | NXT2 | 3.95e+00 | 9.82e-01 | 2.73e+00 | 1.30e-03 | Male-biased |
| PCPG | STAT5B | NXT2 | 4.40e+00 | 9.80e-01 | 3.62e+00 | 1.12e-02 | Male-biased |
| PCPG | ZBTB33 | NXT2 | 5.93e+00 | 9.82e-01 | 5.24e+00 | 1.69e-02 | Male-biased |
| PCPG | ZNF25 | NXT2 | 4.57e+00 | 9.93e-01 | 2.78e+00 | 7.01e-05 | Male-biased |
| PCPG | ZNF35 | NXT2 | 4.55e+00 | 9.93e-01 | 2.92e+00 | 1.56e-04 | Male-biased |
| PCPG | ZNF418 | NXT2 | 4.60e+00 | 9.94e-01 | 2.05e+00 | 1.92e-06 | Male-biased |
| PCPG | ZNF879 | NXT2 | 4.13e+00 | 9.87e-01 | 2.28e+00 | 4.74e-05 | Male-biased |
| PCPG | ZSCAN9 | NXT2 | 4.40e+00 | 9.86e-01 | 3.47e+00 | 5.56e-03 | Male-biased |
| THYM | ZNF418 | NXT2 | 3.93e+00 | 1.00e-02 | 4.62e+00 | 9.83e-01 | Female-biased |
| NXT2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for NXT2 |
| RBPs related to ES in NXT2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| NXT2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg13257485 | |
| Position to Gene: promoter | |
| Male Effect: -0.259336524290746 | |
| Female Effect: - | |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg26144456 | |
| Position to Gene: promoter | |
| Male Effect: -0.291306275157235 | |
| Female Effect: - | |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg15586998 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.391248134799604 | |
| Female Effect: - | |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg15586998 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.230369426843941 | |
| Female Effect: - | |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg26144456 | |
| Position to Gene: promoter | |
| Male Effect: -0.119612932037446 | |
| Female Effect: - | |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg26144456 | |
| Position to Gene: promoter | |
| Male Effect: -0.285826979125899 | |
| Female Effect: - | |
 | Gene ID: ENSG00000101888 |
| CpG Site: cg15586998 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.285826979125899 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg13257485 | chrX:109535625 | promoter | -0.259336524290746 | 7.48473303206393e-15 | -0.5453185246942087 | 2.7498087137847807e-18 | LUAD |
| cg26144456 | chrX:109535777 | promoter | -0.291306275157235 | 1.4787269518082e-08 | -0.4408236110947786 | 7.104213224148683e-12 | STAD |
| cg15586998 | chrX:109535801 | gene,exon,promoter,UTR | -0.391248134799604 | 1.31533768188797e-07 | -0.41762384362491556 | 1.0712155232292148e-10 | STAD |
| cg15586998 | chrX:109535801 | gene,exon,promoter,UTR | -0.230369426843941 | 3.36788839228858e-14 | -0.5057364646454143 | 9.060979872519514e-18 | LIHC |
| cg26144456 | chrX:109535777 | promoter | -0.119612932037446 | 2.46085296600667e-07 | -0.34157893789032046 | 9.00235672182151e-10 | BLCA |
| cg26144456 | chrX:109535777 | promoter | -0.285826979125899 | 2.20194729564311e-07 | -0.3101348704620286 | 1.2038372963467118e-09 | HNSC |
| cg15586998 | chrX:109535801 | gene,exon,promoter,UTR | -0.285826979125899 | 2.20194729564311e-07 | -0.3101348704620286 | 1.2038372963467118e-09 | HNSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of NXT2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
