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Gene: ENSG00000100325

Summary for ASCC2

Gene summary

Gene information	Ensembl ID	ENSG00000100325
	Gene symbol	ASCC2
	Gene name	activating signal cointegrator 1 complex subunit 2
	HGNC	24103
	Entrez ID	84164
	Gene type	protein_coding
	Synonyms	ASCC2\|ASC1p100\|FLJ21588\|DKFZp586O0223
	UniProtAcc	Q9H1I8

Drugs associated with this gene(DrugBank).

Gene ID

Gene Symbol

Drug ID

Drug Name

Drug Type

Cancer therapeutic drugs associated with this gene(NCI).

Gene ID

Gene Name

Drug ID

Drug Name

Drug Type

Cancer

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Structure and expression level for ASCC2

AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.

Landscape of gene expressions across multiple cancer types.

Differentially expressed gene analysis between tumor male and tumor female samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

Differentially expressed gene analysis between tumor male and normal male samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
ASCC2	8.27e+03	1.17e+00	2.90e-01	4.03e+00	5.68e-05	2.71e-04	BLCA

Differentially expressed gene analysis between tumor female and normal female samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

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Sex-biased somatic mutation for ASCC2

∗For more information on exon skipping events please check the ExonskipDB database.

Gene ID

Cancer Type

Hugo Symbol

Male

Female

pval

ci.up

ci.low

adjPval

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DNA methylation with beta values for ASCC2

Landscape of DNA methylation across multiple cancer types.

Differentially expressed CpG sites between male tumor and female tumor patients.

Cancer Type

CpG Site

Position

CpG Island

Position to Gene

ave1

ave2

wilcoxon.w

wilcoxon.p

padj

dBeta

Differentially expressed CpG sites between male tumor and male normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
KIRC	cg01746044	chr22:29838786	CGI:chr22:29837934-29838410	promoter	2.06e-01	3.10e-01	-3.63e+00	2.79e-04	5.03e-04	-1.03e-01
LUSC	cg01746044	chr22:29838786	CGI:chr22:29837934-29838410	promoter	1.36e-01	2.74e-01	-4.16e+00	3.13e-05	5.26e-04	-1.39e-01
CHOL	cg01746044	chr22:29838786	CGI:chr22:29837934-29838410	promoter	2.31e-01	4.33e-01	-2.36e+00	1.83e-02	2.92e-02	-2.01e-01

Differentially expressed CpG sites between female tumor and female normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
KIRP	cg01746044	chr22:29838786	CGI:chr22:29837934-29838410	promoter	2.40e-01	3.43e-01	-2.26e+00	2.36e-02	2.99e-02	-1.03e-01

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Exon skipping events with PSI in TCGA for ASCC2

∗Please access ExonSkipDB for exon skipping annotation.

Landscape of exon skipping events across multiple cancer types.

Differentially expressed exon skipping events between male tumor and female tumor patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between male tumor and male normal patients.

Cancer Type	Exon Skipping	ave.female_T	ave.female_N	wilcoxon.w	wilcoxon.p	padj	dPSI
HNSC	exon_skip_368479	5.45e-01	4.41e-01	4.60e+00	4.31e-06	5.50e-05	1.04e-01
BLCA	exon_skip_368479	5.24e-01	3.43e-01	2.28e+00	2.25e-02	3.30e-02	1.81e-01
KICH	exon_skip_368479	4.40e-01	6.05e-01	-3.13e+00	1.74e-03	7.07e-03	-1.65e-01

Differentially expressed exon skipping events between female tumor and female normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

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RNA A-to-I editing events in TCGA for ASCC2

∗Please access CAeditome for RNA editing annotation.

Differentially expressed RNA editing events between male tumor and female tumor patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between male tumor and male normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between female tumor and female normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Protein coding RNA editing(s).

Editing Position

Variant Type

Gene Symbol

Transcript ID

NTchange

AAchange

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Sex-biased TF-Gene network for ASCC2

TFs related to ASCC2.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type

Target Gene

Male Edge Score

Male Edge Threshold

Female Edge Score

Female Edge Threshold

Type

ASCC2 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for ASCC2

RBPs related to ES in ASCC2.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type	RBP	Target ES	Male Edge Score	Male Edge Threshold	Female Edge Score	Female Edge Threshold	Type
ACC	FXR1	exon_skip_368367	1.22e+01	9.96e-01	1.16e+01	3.72e-03	Male-biased
THYM	HNRNPH2	exon_skip_368424	8.55e+00	9.92e-01	8.03e+00	1.28e-03	Male-biased
LIHC	FXR1	exon_skip_368367	1.16e+01	4.00e-03	1.21e+01	9.95e-01	Female-biased
COAD	FXR1	exon_skip_368367	1.21e+01	9.97e-01	1.16e+01	2.01e-03	Male-biased
CHOL	FXR1	exon_skip_368367	1.16e+01	2.98e-03	1.22e+01	9.96e-01	Female-biased
ESCA	FXR1	exon_skip_368367	1.15e+01	1.27e-02	1.19e+01	9.87e-01	Female-biased
READ	SRSF9	exon_skip_368381	6.24e+00	3.12e-03	6.68e+00	9.81e-01	Female-biased
PCPG	FXR1	exon_skip_368367	1.22e+01	9.98e-01	1.18e+01	1.89e-03	Male-biased
KIRC	HNRNPH2	exon_skip_368424	8.28e+00	9.87e-01	7.92e+00	5.36e-03	Male-biased
HNSC	HNRNPH2	exon_skip_368424	7.97e+00	3.97e-04	8.62e+00	9.94e-01	Female-biased
SARC	FXR1	exon_skip_368367	1.21e+01	9.95e-01	1.16e+01	4.16e-03	Male-biased
SARC	SAMD4A	exon_skip_368373	6.54e+00	9.82e-01	5.58e+00	9.84e-05	Male-biased

ASCC2 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

Sex-biased CeRNA regulation of gene.

Gene ID

ceRNA(lncRNA-miRNA-mRNA)

Group

Cancer Type

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Sex-biased eQTL regulation of gene

Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

eQTL

Description

Male-specific eQTL regulation.

SNP ID	SNP Info	Position to Gene	Effect Score	FDR	Cancer Type	Biased Type
rs73156461	chr22:32752116:C:T	-	0.227016070465845	0.00675771788209473	GBM	Female-baised eQTL
rs9941965	chr22:28807414:G:A	-	0.27624690583616	0.0320836749372787	GBM	Female-baised eQTL
rs9623016	chr22:39545930:C:T	-	0.256334229096419	0.0408280160463253	GBM	Female-baised eQTL
rs11913794	chr22:27160617:G:A	-	-0.0659131859322039	0.0131607675093423	THCA	Female-baised eQTL
rs2205969	chr22:39799012:C:A	-	0.171402407019418	0.00317889581744587	KIRP	Female-baised eQTL
rs2266999	chr22:23109588:G:C	-	0.116388889807341	0.0421614030229053	KIRP	Female-baised eQTL
rs74556925	chr22:20385045:G:A	-	0.240712265435404	0.0422026843399531	KIRP	Female-baised eQTL
rs5760515	chr22:20386770:G:A	-	0.240712265435404	0.0422026843399531	KIRP	Female-baised eQTL
rs2041970	chr22:20389428:T:G	-	0.240712265435404	0.0422026843399531	KIRP	Female-baised eQTL
rs5760821	chr22:20391090:T:A	-	0.240712265435404	0.0422026843399531	KIRP	Female-baised eQTL
rs11704853	chr22:20408665:C:T	-	0.239859963546093	0.0443951701277372	KIRP	Female-baised eQTL
rs134021	chr22:27646073:G:A	-	0.0742095293179518	8.97283240294593e-05	LUAD	Female-baised eQTL
rs12185878	chr22:36174640:A:G	-	-0.0773963001485839	0.0309821075900518	COAD	Female-baised eQTL
rs6005516	chr22:27571272:G:A	-	-0.0800474653728191	0.0424926710022068	COAD	Female-baised eQTL

Female-specific eQTL regulation.

SNP ID	SNP Info	Position to Gene	Effect Score	FDR	Cancer Type	Biased Type
rs5752412	chr22:26779033:G:A	-	0.0645041887127787	0.0196343891036736	LIHC	Male-baised eQTL
rs5752413	chr22:26779895:G:A	-	0.0608879486212039	0.0240406509998027	LIHC	Male-baised eQTL
rs5761748	chr22:26781392:A:G	-	0.0616276683822444	0.0255901993464464	LIHC	Male-baised eQTL
rs7287853	chr22:32241161:T:C	-	-0.0574477283902619	0.0336831216445099	LIHC	Male-baised eQTL
rs5754387	chr22:21620414:G:C	-	0.0542251961297867	0.0421498388388021	LIHC	Male-baised eQTL
rs2899185	chr22:32357826:T:A	-	0.106936549638686	0.00248531555817542	BLCA	Male-baised eQTL
rs5753625	chr22:31458860:T:C	-	0.0627484612728796	0.00591077082057155	BLCA	Male-baised eQTL
rs2103853	chr22:31459489:T:C	-	0.0609209042785265	0.0106852489018263	BLCA	Male-baised eQTL
rs11913992	chr22:31189234:G:A	-	-0.0581800831893955	0.0198823466770527	BLCA	Male-baised eQTL
rs6518737	chr22:31186676:A:G	-	-0.0570615639330059	0.0233750470486621	BLCA	Male-baised eQTL
rs5997899	chr22:31181864:G:A	-	-0.0564535190250642	0.0270645243240222	BLCA	Male-baised eQTL
rs9637317	chr22:35554805:C:T	-	0.0754505849858574	0.0298327281950748	BLCA	Male-baised eQTL
rs62219901	chr22:20129071:G:A	-	0.0763325838431457	0.0410484772147661	BLCA	Male-baised eQTL
rs4820948	chr22:31169108:A:G	-	-0.0538828191433425	0.0442220261571818	BLCA	Male-baised eQTL
rs5997896	chr22:31170392:A:G	-	-0.0535815491931776	0.047641998970712	BLCA	Male-baised eQTL
rs79279423	chr22:26410034:C:T	-	0.108147966907394	0.0483033221318109	BLCA	Male-baised eQTL
rs2239783	chr22:36309082:C:T	-	0.055532089284453	0.0487518463421705	BLCA	Male-baised eQTL
rs75616273	chr22:26410463:C:G	-	0.107989132271698	0.0491622952879306	BLCA	Male-baised eQTL
rs695423	chr22:25835000:A:G	-	0.0488406885767668	0.00196233736878949	COAD	Male-baised eQTL
rs5999839	chr22:35497664:A:G	-	0.0771288359638074	0.00271078682304521	COAD	Male-baised eQTL
rs9621741	chr22:33650852:C:G	-	0.0702758642840385	0.00292594488321087	COAD	Male-baised eQTL
rs5752605	chr22:27656156:A:G	-	0.0636048002630483	0.0037395864025885	COAD	Male-baised eQTL
rs3859878	chr22:25827040:T:C	-	-0.0786516365493929	0.00554653579642496	COAD	Male-baised eQTL
rs3788487	chr22:32731430:C:G	-	0.0308049775251253	0.00588185337145461	COAD	Male-baised eQTL
rs5994838	chr22:34088141:T:A	-	0.0528889025650454	0.00683858159129503	COAD	Male-baised eQTL
rs2413016	chr22:31062217:C:T	-	0.0417847367930977	0.00830904742865479	COAD	Male-baised eQTL
rs9622106	chr22:35040801:G:T	-	0.0769775290940137	0.00831658074218754	COAD	Male-baised eQTL
rs2016130	chr22:31066321:A:T	-	0.0402880657513973	0.00952651439293019	COAD	Male-baised eQTL
rs5999835	chr22:35497536:T:C	-	0.0676987607943261	0.0104273856204151	COAD	Male-baised eQTL
rs5999836	chr22:35497544:A:C	-	0.0676987607943261	0.0104273856204151	COAD	Male-baised eQTL
rs5999837	chr22:35497562:T:G	-	0.0676987607943261	0.0104273856204151	COAD	Male-baised eQTL
rs5753449	chr22:31068240:A:G	-	0.0416848256284722	0.0107267172675278	COAD	Male-baised eQTL
rs1990125	chr22:31068419:T:C	-	0.0416848256284722	0.0107267172675278	COAD	Male-baised eQTL
rs9619508	chr22:35044229:G:A	-	0.0725779041534554	0.0109524014571654	COAD	Male-baised eQTL
rs2014680	chr22:37784355:A:G	-	0.0676275828933053	0.0129182051971745	COAD	Male-baised eQTL
rs5753446	chr22:31055978:G:C	-	0.0393280690246074	0.0131476005677095	COAD	Male-baised eQTL
rs16995748	chr22:35497489:A:G	-	0.0644469591846804	0.0158763950955045	COAD	Male-baised eQTL
rs5999838	chr22:35497605:A:G	-	0.0644469591846804	0.0158763950955045	COAD	Male-baised eQTL
rs5999840	chr22:35497725:G:T	-	0.0644469591846804	0.0158763950955045	COAD	Male-baised eQTL
rs853295	chr22:20700300:T:C	-	0.0296041488602662	0.0159915776272453	COAD	Male-baised eQTL
rs6000909	chr22:37852982:T:C	-	0.0592011125149276	0.0167946489534038	COAD	Male-baised eQTL
rs112158446	chr22:28845574:G:C	-	0.0432404009941201	0.0171611345153372	COAD	Male-baised eQTL
rs6004026	chr22:20712214:T:C	-	0.0292998175287397	0.019062805342	COAD	Male-baised eQTL
rs16997833	chr22:37159792:G:C	-	-0.0648174019930454	0.0195956184612949	COAD	Male-baised eQTL
rs4820579	chr22:20721841:C:T	-	0.0292131663834046	0.020369946500659	COAD	Male-baised eQTL
rs9609944	chr22:34099827:C:T	-	0.0521611075799669	0.0225201449998739	COAD	Male-baised eQTL
rs5751786	chr22:20711644:A:T	-	0.0290605337167085	0.0234839398537369	COAD	Male-baised eQTL
rs191025226	chr22:27981230:A:T	-	0.0571641459436342	0.023671388290574	COAD	Male-baised eQTL
rs200593427	chr22:20696587:C:T	-	0.0290183485682086	0.023859441349958	COAD	Male-baised eQTL
rs5760087	chr22:20699382:C:T	-	0.0290183485682086	0.023859441349958	COAD	Male-baised eQTL
rs5995705	chr22:39265538:G:A	-	0.0587350635796715	0.0244596569031822	COAD	Male-baised eQTL
rs62231493	chr22:39269055:C:T	-	0.0708092209627983	0.0246167155251434	COAD	Male-baised eQTL
rs73156787	chr22:31103769:G:A	-	-0.0472498134033192	0.0283034327767461	COAD	Male-baised eQTL
rs917208	chr22:31097139:G:A	-	-0.04716386915971	0.0284394649343589	COAD	Male-baised eQTL
rs5998879	chr22:33334109:C:T	-	0.0570703764371224	0.0302603434217187	COAD	Male-baised eQTL
rs2188131	chr22:22939433:T:C	-	0.0428328629550743	0.0314050296821101	COAD	Male-baised eQTL
rs2329478	chr22:20714590:C:T	-	0.0289444802318629	0.0332642520810758	COAD	Male-baised eQTL
rs3925154	chr22:25836649:A:C	-	-0.0296779864388569	0.0341271649386253	COAD	Male-baised eQTL
rs4820575	chr22:20706071:A:C	-	0.0284480430408426	0.0369421158749186	COAD	Male-baised eQTL
rs5760196	chr22:20722465:T:G	-	0.0282178350129942	0.0383552022244309	COAD	Male-baised eQTL
rs5760197	chr22:20722466:T:C	-	0.0282178350129942	0.0383552022244309	COAD	Male-baised eQTL
rs132546	chr22:28919797:A:G	-	-0.0401676493488097	0.0389483440717603	COAD	Male-baised eQTL
rs4822471	chr22:20721920:G:T	-	0.0287117642038363	0.0395739568895055	COAD	Male-baised eQTL
rs132645	chr22:36152358:G:A	-	-0.0383328737461578	0.0429509194273627	COAD	Male-baised eQTL
rs111896350	chr22:33333057:A:C	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs113482929	chr22:33333088:G:A	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs112447117	chr22:33333119:G:T	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs112632309	chr22:33333176:A:C	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs76796241	chr22:33333313:G:C	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs73401440	chr22:33333413:C:T	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs5998877	chr22:33333881:G:A	-	0.0541187006816029	0.0436665037169864	COAD	Male-baised eQTL
rs7284929	chr22:22044503:T:A	-	0.0558996463579021	0.0437622419569136	COAD	Male-baised eQTL
rs73156781	chr22:31084209:C:T	-	-0.0429243986125818	0.0439470742519307	COAD	Male-baised eQTL
rs5751800	chr22:20721249:A:C	-	0.0281883571606699	0.0457478588210379	COAD	Male-baised eQTL
rs2080335	chr22:20719749:G:A	-	0.0281315391274478	0.0467046755787845	COAD	Male-baised eQTL
rs2301440	chr22:26601518:T:C	-	0.0276389861354452	0.0475466361128185	COAD	Male-baised eQTL
rs7291036	chr22:36406502:T:C	-	-0.027613380342638	0.0490154232535043	COAD	Male-baised eQTL
rs1807692	chr22:20718834:G:A	-	0.0274502534124605	0.0497699134798114	COAD	Male-baised eQTL

Opposite sex-biased eQTL regulation.

SNP ID

SNP Info

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Sex-biased Gene in Cancer

Cancer Type

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Sex-biased eQTM regulation of gene

Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).

eQTM	Description
	Gene ID: ENSG00000100325
	CpG Site: cg14742445
	Position to Gene: gene
	Male Effect: -
	Female Effect: -0.060640812852108

Male-specific eQTM regulation.

CpG Site

CpG Postion

Position to Gene

Effect Score

FDR

Cor.r

Cor.Pvalue

Cancer Type

Female-specific eQTM regulation.

CpG Site	CpG Postion	Position to Gene	Effect Score	FDR	Cor.r	Cor.Pvalue	Cancer Type
cg14742445	chr22:29799310	gene	-0.060640812852108	1.24602999311141e-05	-0.33479566870587996	4.2793206531483116e-08	LUAD

Opposite sex-biased eQTM regulation.

CpG Site

CpG Postion

CpG Island

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Male Cor

Male P-value

Female Cor

Female P-value

Sex-biased Coding Gene

Cancer Type

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Sex-biased sQTL regulation of gene

Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTL

Description

Male-specific sQTL regulation.

ES ID	Skipped Exon	ORF Anno	SNP ID	SNP Info	SNP Position to ES	Effect Score	FDR	Cancer Type	Biased Type
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs140143	chr22:29777120:G:C	Distant downstream	-0.0636857099684024	0.0388289656022194	KIRC	Female-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5763863	chr22:30185870:A:T	Distant upstream	-0.0691218709258704	0.0451642836484456	KIRC	Female-baised sQTL
exon_skip_368399	chr22:29825621:29825780	In-frame	rs132556	chr22:28938612:C:T	Distant downstream	0.0233397573387616	0.0276955042637381	LUAD	Female-baised sQTL
exon_skip_368399	chr22:29825621:29825780	In-frame	rs1076296	chr22:30365309:G:A	Distant upstream	-0.0540116133654878	0.0423861143064363	LUSC	Female-baised sQTL

Female-specific sQTL regulation.

ES ID	Skipped Exon	ORF Anno	SNP ID	SNP Info	SNP Position to ES	Effect Score	FDR	Cancer Type	Biased Type
exon_skip_368436	chr22:29832244:29832342	3UTR-3CDS	rs5763243	chr22:29444351:C:T	Distant downstream	-0.0238775965350098	0.0475933263906419	KIRC	Male-baised sQTL
exon_skip_368436	chr22:29832244:29832342	3UTR-3CDS	rs73159014	chr22:29537298:G:A	Distant downstream	-0.0310970181613114	0.0217341021531325	LUAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5762857	chr22:28851109:A:G	Distant downstream	-0.0868759372547153	0.00677315110656776	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs34206997	chr22:28860105:T:A	Distant downstream	-0.0868759372547153	0.00677315110656776	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5752814	chr22:28834669:T:A	Distant downstream	-0.0718295678393306	0.0094087939174189	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5752815	chr22:28834745:C:A	Distant downstream	-0.0718295678393306	0.0094087939174189	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5762835	chr22:28834766:A:G	Distant downstream	-0.0718295678393306	0.0094087939174189	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs13053879	chr22:28863114:T:A	Distant downstream	-0.0841661494559407	0.0122172431918571	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs377310282	chr22:28867244:A:G	Distant downstream	-0.0835398387675603	0.0124629966485427	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs2881634	chr22:28838549:A:G	Distant downstream	-0.0804916128448401	0.013373100541203	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5752816	chr22:28839985:G:A	Distant downstream	-0.0804916128448401	0.013373100541203	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs60468718	chr22:28841970:C:G	Distant downstream	-0.0804916128448401	0.013373100541203	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5762839	chr22:28835459:C:T	Distant downstream	-0.0678207239763198	0.0150649694555443	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs5762838	chr22:28835210:G:A	Distant downstream	-0.0690798661028739	0.0157768996147874	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs80143671	chr22:28867116:A:G	Distant downstream	-0.0788027229503994	0.0281566689696433	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs2347448	chr22:28868965:C:T	Distant downstream	-0.0788027229503994	0.0281566689696433	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs9625591	chr22:28836576:A:G	Distant downstream	-0.0659342043662807	0.0374114507698993	COAD	Male-baised sQTL
exon_skip_368479	chr22:29834488:29834550	3UTR-3UTR	rs6005917	chr22:28837498:A:G	Distant downstream	-0.0659342043662807	0.0374114507698993	COAD	Male-baised sQTL

Opposite sex-biased sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Male Effect

Male FDR

Female Effect

Female FDR

Cancer Type

Top

Sex-biased sQTM regulation of gene

Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTM

Description

Male-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Female-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Opposite sex-biased sQTM regulation.

EX ID

EX Info

Skipped Exon

CPG Site

CPG Position

CPG Island

Position to EX Events

Male Effect

Male FDR

Female Effect

Female FDR

Male Correlation

Male P-value

Female Correlation

Female P-value

ORF_anno

Cancer Type

Top

Related disease information of ASCC2

Diseases associated with this gene (DisGeNET).

Gene ID

Gene Symbol

Disease ID

Disease Name

Number of PMID

Source

	Gene summary
	Gene structure and Gene expression level
	Sex-biased somatic mutation
	DNA methylation with beta values in gene
	Exon skipping events with PSI in TCGA
	RNA A-to-I editing events in TCGA
	Sex-biased TF-Gene network of gene
	Sex-biased RBP-ES network of gene
	Sex-biased CeRNA regulation of gene
	Sex-biased eQTL regulation of gene
	Sex-biased eQTM regulation of gene
	Sex-biased sQTL regulation of gene
	Sex-biased sQTM regulation of gene
	Related disease information of gene