|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000099889 |
Summary for ARVCF |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000099889 | Gene symbol | ARVCF |
| Gene name | ARVCF delta catenin family member | |
| HGNC | 728 | |
| Entrez ID | 421 | |
| Gene type | protein_coding | |
| Synonyms | ARVCF| | |
| UniProtAcc | O00192 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ARVCF |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ARVCF | 9.94e+02 | 1.07e+00 | 3.61e-01 | 2.97e+00 | 3.01e-03 | 1.95e-02 | BLCA |
| ARVCF | 6.60e+02 | 1.21e+00 | 1.90e-01 | 6.39e+00 | 1.69e-10 | 9.71e-10 | COAD |
| ARVCF | 6.67e+02 | 1.08e+00 | 2.87e-01 | 3.75e+00 | 1.77e-04 | 7.86e-04 | READ |
Top |
Sex-biased somatic mutation for ARVCF |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for ARVCF |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for ARVCF |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| THCA | exon_skip_367534 | 7.24e-01 | 8.37e-01 | -4.21e+00 | 2.59e-05 | 3.59e-04 | -1.13e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_367534 | 6.43e-01 | 3.17e-01 | 9.48e+00 | 2.58e-21 | 6.45e-20 | 3.26e-01 |
| READ | exon_skip_367550 | 9.65e-03 | 1.13e-01 | -2.55e+00 | 1.06e-02 | 2.32e-02 | -1.03e-01 |
Top |
RNA A-to-I editing events in TCGA for ARVCF |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for ARVCF |
| TFs related to ARVCF. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | ASCL1 | ARVCF | 2.83e+00 | 4.19e-03 | 4.31e+00 | 9.82e-01 | Female-biased |
| BRCA | NR1H4 | ARVCF | 3.25e+00 | 8.13e-03 | 4.52e+00 | 9.82e-01 | Female-biased |
| BRCA | PATZ1 | ARVCF | 3.15e+00 | 7.36e-03 | 4.46e+00 | 9.82e-01 | Female-biased |
| BRCA | PLAG1 | ARVCF | 3.12e+00 | 4.73e-03 | 4.57e+00 | 9.87e-01 | Female-biased |
| BRCA | SNAI1 | ARVCF | 2.98e+00 | 2.88e-03 | 4.59e+00 | 9.89e-01 | Female-biased |
| BRCA | TCF12 | ARVCF | 2.80e+00 | 3.71e-03 | 4.31e+00 | 9.82e-01 | Female-biased |
| BRCA | TCF3 | ARVCF | 3.03e+00 | 3.36e-03 | 4.59e+00 | 9.88e-01 | Female-biased |
| BRCA | TFAP2A | ARVCF | 3.23e+00 | 6.49e-03 | 4.58e+00 | 9.85e-01 | Female-biased |
| BRCA | TFAP2B | ARVCF | 3.19e+00 | 4.88e-03 | 4.63e+00 | 9.87e-01 | Female-biased |
| BRCA | TFAP2C | ARVCF | 3.15e+00 | 6.05e-03 | 4.52e+00 | 9.84e-01 | Female-biased |
| BRCA | ZFX | ARVCF | 3.09e+00 | 5.22e-03 | 4.50e+00 | 9.85e-01 | Female-biased |
| BRCA | ZIC2 | ARVCF | 2.77e+00 | 2.61e-03 | 4.41e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF101 | ARVCF | 3.04e+00 | 5.26e-03 | 4.45e+00 | 9.84e-01 | Female-biased |
| BRCA | ZNF141 | ARVCF | 3.30e+00 | 6.46e-03 | 4.65e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF16 | ARVCF | 3.07e+00 | 7.29e-03 | 4.37e+00 | 9.80e-01 | Female-biased |
| BRCA | ZNF19 | ARVCF | 3.11e+00 | 7.65e-03 | 4.40e+00 | 9.80e-01 | Female-biased |
| BRCA | ZNF264 | ARVCF | 3.26e+00 | 8.01e-03 | 4.54e+00 | 9.83e-01 | Female-biased |
| BRCA | ZNF28 | ARVCF | 3.20e+00 | 5.01e-03 | 4.63e+00 | 9.87e-01 | Female-biased |
| BRCA | ZNF331 | ARVCF | 3.06e+00 | 6.99e-03 | 4.38e+00 | 9.80e-01 | Female-biased |
| BRCA | ZNF415 | ARVCF | 3.02e+00 | 6.30e-03 | 4.38e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF431 | ARVCF | 3.12e+00 | 7.11e-03 | 4.44e+00 | 9.82e-01 | Female-biased |
| BRCA | ZNF454 | ARVCF | 3.17e+00 | 6.71e-03 | 4.50e+00 | 9.83e-01 | Female-biased |
| BRCA | ZNF479 | ARVCF | 3.18e+00 | 5.97e-03 | 4.55e+00 | 9.85e-01 | Female-biased |
| BRCA | ZNF692 | ARVCF | 3.19e+00 | 4.58e-03 | 4.65e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF707 | ARVCF | 3.08e+00 | 7.21e-03 | 4.39e+00 | 9.80e-01 | Female-biased |
| BRCA | ZNF793 | ARVCF | 3.20e+00 | 8.12e-03 | 4.47e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF816 | ARVCF | 2.96e+00 | 5.76e-03 | 4.34e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF891 | ARVCF | 3.10e+00 | 4.86e-03 | 4.54e+00 | 9.86e-01 | Female-biased |
| ARVCF related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ARVCF |
| RBPs related to ES in ARVCF. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LUSC | RBM4 | exon_skip_367537 | 8.98e+00 | 9.92e-01 | 8.51e+00 | 4.08e-03 | Male-biased |
| COAD | ANKHD1 | exon_skip_367542 | 1.68e+01 | 9.99e-01 | 1.61e+01 | 4.97e-04 | Male-biased |
| COAD | PPRC1 | exon_skip_367541 | 1.16e+01 | 1.96e-03 | 1.21e+01 | 9.98e-01 | Female-biased |
| COAD | RBM4 | exon_skip_367541 | 8.51e+00 | 5.25e-03 | 8.90e+00 | 9.90e-01 | Female-biased |
| COAD | RBM8A | exon_skip_367541 | 1.12e+01 | 1.77e-03 | 1.17e+01 | 9.98e-01 | Female-biased |
| COAD | ZC3H10 | exon_skip_367536 | 7.55e+00 | 7.68e-03 | 7.91e+00 | 9.84e-01 | Female-biased |
| CHOL | ANKHD1 | exon_skip_367542 | 1.71e+01 | 1.03e-03 | 1.78e+01 | 9.99e-01 | Female-biased |
| BRCA | ANKHD1 | exon_skip_367542 | 1.69e+01 | 9.90e-01 | 1.64e+01 | 1.04e-02 | Male-biased |
| BRCA | RBM4 | exon_skip_367537 | 8.77e+00 | 8.86e-03 | 9.44e+00 | 9.88e-01 | Female-biased |
| BRCA | ZC3H10 | exon_skip_367536 | 7.25e+00 | 1.46e-03 | 8.51e+00 | 9.92e-01 | Female-biased |
| ESCA | ANKHD1 | exon_skip_367542 | 1.60e+01 | 2.47e-03 | 1.67e+01 | 9.98e-01 | Female-biased |
| READ | ANKHD1 | exon_skip_367542 | 1.69e+01 | 1.00e+00 | 1.62e+01 | 3.97e-04 | Male-biased |
| THCA | ZC3H10 | exon_skip_367536 | 7.37e+00 | 9.71e-03 | 7.67e+00 | 9.81e-01 | Female-biased |
| PCPG | ANKHD1 | exon_skip_367542 | 1.60e+01 | 1.92e-04 | 1.67e+01 | 1.00e+00 | Female-biased |
| PCPG | PPRC1 | exon_skip_367541 | 1.09e+01 | 6.08e-03 | 1.12e+01 | 9.93e-01 | Female-biased |
| PCPG | RBM8A | exon_skip_367541 | 1.09e+01 | 9.48e-03 | 1.12e+01 | 9.90e-01 | Female-biased |
| MESO | ANKHD1 | exon_skip_367542 | 1.58e+01 | 3.80e-04 | 1.65e+01 | 1.00e+00 | Female-biased |
| MESO | PPRC1 | exon_skip_367541 | 1.10e+01 | 3.33e-03 | 1.15e+01 | 9.96e-01 | Female-biased |
| MESO | RBM4 | exon_skip_367541 | 8.38e+00 | 9.77e-03 | 8.73e+00 | 9.85e-01 | Female-biased |
| MESO | RBM8A | exon_skip_367541 | 1.10e+01 | 3.50e-03 | 1.14e+01 | 9.96e-01 | Female-biased |
| KIRC | ANKHD1 | exon_skip_367542 | 1.68e+01 | 1.00e+00 | 1.61e+01 | 1.30e-04 | Male-biased |
| KICH | PPRC1 | exon_skip_367541 | 1.12e+01 | 1.13e-03 | 1.17e+01 | 9.98e-01 | Female-biased |
| KICH | RBM4 | exon_skip_367541 | 8.33e+00 | 3.46e-03 | 8.74e+00 | 9.91e-01 | Female-biased |
| KICH | RBM8A | exon_skip_367541 | 1.10e+01 | 7.34e-04 | 1.16e+01 | 9.99e-01 | Female-biased |
| BLCA | ANKHD1 | exon_skip_367542 | 1.65e+01 | 1.29e-03 | 1.70e+01 | 9.99e-01 | Female-biased |
| SKCM | ANKHD1 | exon_skip_367542 | 1.61e+01 | 6.44e-04 | 1.68e+01 | 9.99e-01 | Female-biased |
| HNSC | ZC3H10 | exon_skip_367536 | 8.06e+00 | 9.87e-01 | 7.64e+00 | 4.62e-03 | Male-biased |
| ARVCF related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs151290801 | chr22:24511648:C:G | - | 0.113964594961836 | 0.000149066697988722 | LUSC | Female-baised eQTL |
| rs73167602 | chr22:24396695:A:T | - | 0.135670065383717 | 0.00089419290864203 | LUSC | Female-baised eQTL |
| rs7285057 | chr22:24426695:T:C | - | 0.10715339993033 | 0.00123391490050442 | LUSC | Female-baised eQTL |
| rs1015011 | chr22:24497053:C:G | - | 0.10085551698985 | 0.00136769372757321 | LUSC | Female-baised eQTL |
| rs9620388 | chr22:24463699:A:C | - | 0.102915195121116 | 0.00232206812441039 | LUSC | Female-baised eQTL |
| rs9624480 | chr22:24475974:C:T | - | 0.102915195121116 | 0.00232206812441039 | LUSC | Female-baised eQTL |
| rs372567965 | chr22:24477183:G:C | - | 0.102915195121116 | 0.00232206812441039 | LUSC | Female-baised eQTL |
| rs73879064 | chr22:24477558:G:A | - | 0.102915195121116 | 0.00232206812441039 | LUSC | Female-baised eQTL |
| rs9624482 | chr22:24482238:G:A | - | 0.102915195121116 | 0.00232206812441039 | LUSC | Female-baised eQTL |
| rs9624472 | chr22:24438763:A:G | - | 0.102647197272943 | 0.00250050708316813 | LUSC | Female-baised eQTL |
| rs1964959 | chr22:24446947:T:C | - | 0.102647197272943 | 0.00250050708316813 | LUSC | Female-baised eQTL |
| rs7290459 | chr22:24450021:C:A | - | 0.102647197272943 | 0.00250050708316813 | LUSC | Female-baised eQTL |
| rs73169823 | chr22:24450509:C:T | - | 0.102647197272943 | 0.00250050708316813 | LUSC | Female-baised eQTL |
| rs5763911 | chr22:20443002:T:C | - | 0.135684124579658 | 0.00496910927581393 | LUSC | Female-baised eQTL |
| rs17004921 | chr22:24444708:C:T | - | 0.0933523115083036 | 0.0056736393479475 | LUSC | Female-baised eQTL |
| rs73167582 | chr22:24299500:T:C | - | 0.110910927335714 | 0.00599240102362491 | LUSC | Female-baised eQTL |
| rs149317771 | chr22:24301933:C:A | - | 0.110910927335714 | 0.00599240102362491 | LUSC | Female-baised eQTL |
| rs73167588 | chr22:24327504:C:T | - | 0.110910927335714 | 0.00599240102362491 | LUSC | Female-baised eQTL |
| rs5760036 | chr22:20691363:C:T | - | 0.112989669557814 | 0.00865897774093348 | LUSC | Female-baised eQTL |
| rs500570 | chr22:25517754:C:T | - | 0.121381884009291 | 0.014527994143686 | LUSC | Female-baised eQTL |
| rs73169811 | chr22:24422122:G:A | - | 0.101376661360027 | 0.016272278802629 | LUSC | Female-baised eQTL |
| rs5751757 | chr22:20698702:G:C | - | 0.107567457315325 | 0.0248334965786894 | LUSC | Female-baised eQTL |
| rs373872037 | chr22:20703800:G:A | - | 0.104355482070951 | 0.0290863957374383 | LUSC | Female-baised eQTL |
| rs3890989 | chr22:20695740:A:G | - | 0.106027829742322 | 0.0302314591826987 | LUSC | Female-baised eQTL |
| rs368237505 | chr22:20707070:C:T | - | 0.106027829742322 | 0.0302314591826987 | LUSC | Female-baised eQTL |
| rs13471 | chr22:20707980:G:T | - | 0.106027829742322 | 0.0302314591826987 | LUSC | Female-baised eQTL |
| rs5760139 | chr22:20708525:T:C | - | 0.106027829742322 | 0.0302314591826987 | LUSC | Female-baised eQTL |
| rs9624496 | chr22:20689105:G:A | - | 0.0959776424547074 | 0.0375338526606386 | LUSC | Female-baised eQTL |
| rs9624565 | chr22:24705829:C:T | - | 0.0968660752105369 | 0.040140590599876 | LUSC | Female-baised eQTL |
| rs73159197 | chr22:20686637:A:G | - | 0.0953653485177409 | 0.0411140887918087 | LUSC | Female-baised eQTL |
| rs861825 | chr22:21692029:C:T | - | 0.0690135811578028 | 0.0431983469837901 | LUSC | Female-baised eQTL |
| rs635829 | chr22:25525786:G:A | - | 0.105357454742564 | 0.0456387184446903 | LUSC | Female-baised eQTL |
| rs192565874 | chr22:20688681:G:A | - | 0.0943478980354283 | 0.0461812645650191 | LUSC | Female-baised eQTL |
| rs73159200 | chr22:20713696:G:T | - | 0.100559594356967 | 0.0474146174413373 | LUSC | Female-baised eQTL |
| rs148458689 | chr22:20713737:C:A | - | 0.100559594356967 | 0.0474146174413373 | LUSC | Female-baised eQTL |
| rs12053807 | chr22:20713842:C:T | - | 0.100559594356967 | 0.0474146174413373 | LUSC | Female-baised eQTL |
| rs11090468 | chr22:27033148:C:T | - | 0.108443498502154 | 0.01745331773475 | COAD | Female-baised eQTL |
| rs4822820 | chr22:26927258:T:C | - | 0.0881032640683714 | 0.0458091977231073 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs75039049 | chr22:28842177:A:G | - | 0.183507954006543 | 0.0230820107028087 | SARC | Male-baised eQTL |
| rs80124190 | chr22:28765535:C:T | - | 0.148874367078723 | 0.0335747067674213 | SARC | Male-baised eQTL |
| rs73881132 | chr22:28751305:A:G | - | 0.148794806816331 | 0.034202748453674 | SARC | Male-baised eQTL |
| rs17514713 | chr22:28786082:G:C | - | 0.167943914866121 | 0.0405999900974245 | SARC | Male-baised eQTL |
| rs2105871 | chr22:29840599:G:T | - | 0.0910633394955979 | 0.0437077781916937 | STAD | Male-baised eQTL |
| rs5997539 | chr22:29841717:G:A | - | 0.0910633394955979 | 0.0437077781916937 | STAD | Male-baised eQTL |
| rs6006276 | chr22:29841870:A:T | - | 0.0910633394955979 | 0.0437077781916937 | STAD | Male-baised eQTL |
| rs5762399 | chr22:27910619:T:C | - | 0.0643989954387345 | 0.00166592633007587 | KIRC | Male-baised eQTL |
| rs57423860 | chr22:26041724:G:A | - | 0.0968898602584249 | 0.00229868613475289 | KIRC | Male-baised eQTL |
| rs11913241 | chr22:26043792:G:C | - | 0.0634411343275584 | 0.0033431361397828 | KIRC | Male-baised eQTL |
| rs28529300 | chr22:27893516:C:G | - | 0.0707295230987814 | 0.00393412273716574 | KIRC | Male-baised eQTL |
| rs1016495 | chr22:27892148:T:C | - | 0.068824211179387 | 0.00493165254139517 | KIRC | Male-baised eQTL |
| rs1807581 | chr22:27910082:C:T | - | 0.0670023493087229 | 0.00789708991953241 | KIRC | Male-baised eQTL |
| rs6519637 | chr22:26044738:C:G | - | 0.0585106200189405 | 0.00947827777201715 | KIRC | Male-baised eQTL |
| rs5762321 | chr22:27702112:C:T | - | 0.125889692277488 | 0.0104095542940228 | KIRC | Male-baised eQTL |
| rs6005575 | chr22:27702568:C:T | - | 0.125889692277488 | 0.0104095542940228 | KIRC | Male-baised eQTL |
| rs5762318 | chr22:27700459:G:A | - | 0.125420668800302 | 0.0110262615396059 | KIRC | Male-baised eQTL |
| rs6005445 | chr22:27445557:A:G | - | -0.0722549073085151 | 0.0145332509991006 | KIRC | Male-baised eQTL |
| rs6004913 | chr22:26042529:A:G | - | 0.0565301035299922 | 0.0158020227764705 | KIRC | Male-baised eQTL |
| rs439723 | chr22:22032841:T:A | - | 0.0861406593400076 | 0.0162684954029563 | KIRC | Male-baised eQTL |
| rs5762313 | chr22:27696583:A:G | - | 0.123413271327375 | 0.0170203569390998 | KIRC | Male-baised eQTL |
| rs73431094 | chr22:27696927:T:G | - | 0.123413271327375 | 0.0170203569390998 | KIRC | Male-baised eQTL |
| rs6004912 | chr22:26041549:C:T | - | 0.0612755877499654 | 0.0186581109789383 | KIRC | Male-baised eQTL |
| rs5762314 | chr22:27697982:C:T | - | 0.120391067241451 | 0.0195928590785491 | KIRC | Male-baised eQTL |
| rs5762317 | chr22:27698991:C:T | - | 0.120391067241451 | 0.0195928590785491 | KIRC | Male-baised eQTL |
| rs5762319 | chr22:27700965:A:C | - | 0.0939206171218333 | 0.0200141858320574 | KIRC | Male-baised eQTL |
| rs5762320 | chr22:27701311:C:G | - | 0.0939206171218333 | 0.0200141858320574 | KIRC | Male-baised eQTL |
| rs8141254 | chr22:26036854:T:C | - | 0.0571327097921802 | 0.0220471620043897 | KIRC | Male-baised eQTL |
| rs5997032 | chr22:26041843:T:C | - | 0.0600524178460203 | 0.022698044516354 | KIRC | Male-baised eQTL |
| rs202159847 | chr22:27971717:G:A | - | 0.0484071532489936 | 0.0228576561563572 | KIRC | Male-baised eQTL |
| rs4822987 | chr22:28748512:G:T | - | 0.0520986856420175 | 0.0238206292687874 | KIRC | Male-baised eQTL |
| rs910403 | chr22:27446354:A:T | - | -0.0642698782362448 | 0.0449410572974124 | KIRC | Male-baised eQTL |
| rs134727 | chr22:26117728:G:A | - | 0.0463955064347434 | 0.0459441875198203 | KIRC | Male-baised eQTL |
| rs6003645 | chr22:23358452:T:C | - | -0.0473661613132954 | 0.0377741713986167 | BLCA | Male-baised eQTL |
| rs2518768 | chr22:17486811:G:A | - | -0.0822546833104474 | 0.0195248978951743 | LUAD | Male-baised eQTL |
| rs73427747 | chr22:28186285:G:A | - | 0.13333454440463 | 0.0369306650423463 | LUAD | Male-baised eQTL |
| rs5992111 | chr22:17821817:T:C | - | 0.11922355889442 | 0.0477751897451539 | LUAD | Male-baised eQTL |
| rs5992113 | chr22:17822018:A:C | - | 0.11922355889442 | 0.0477751897451539 | LUAD | Male-baised eQTL |
| rs7285901 | chr22:17055291:T:G | - | 0.102660882087725 | 0.00676477616971911 | COAD | Male-baised eQTL |
| rs12163457 | chr22:24269827:T:C | - | 0.131396488388638 | 0.0107074157530804 | COAD | Male-baised eQTL |
| rs5742310 | chr22:24294674:G:T | - | 0.118800655061779 | 0.0223141955436987 | COAD | Male-baised eQTL |
| rs5762002 | chr22:20411860:T:C | - | 0.0950400579456788 | 0.0374778729368043 | COAD | Male-baised eQTL |
| rs5762013 | chr22:20411988:G:A | - | 0.0947963060477372 | 0.0381951559055989 | COAD | Male-baised eQTL |
| rs5762014 | chr22:20411994:C:A | - | 0.0947963060477372 | 0.0381951559055989 | COAD | Male-baised eQTL |
| rs132546 | chr22:28919797:A:G | - | -0.086251295652616 | 0.0450058341931635 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000099889 |
| CpG Site: cg21797131 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.435494911653669 | |
 | Gene ID: ENSG00000099889 |
| CpG Site: cg01138652 | |
| Position to Gene: gene | |
| Male Effect: -0.0451775695871605 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01138652 | chr22:19986455 | gene | -0.0451775695871605 | 1.78281613175875e-05 | -0.35885618624460225 | 4.353956689946635e-08 | STAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg21797131 | chr22:19983078 | gene | -0.435494911653669 | 7.95345894902866e-14 | -0.4959610168596566 | 3.080040456124473e-17 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2106140 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0498408457118085 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2238791 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0486546959009049 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2518825 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0486655190515591 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs1990277 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0486655190515591 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2531693 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0478413947928358 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2238788 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0483944122566896 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2238793 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0416797097720173 | |
 | EX ID: exon_skip_367534 |
| SNP ID: rs2073745 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.0411682142408306 |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs1134450 | chr22:19849618:T:C | Distant downstream | 0.0562330286976548 | 0.00350793497923797 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs11705553 | chr22:19849387:G:A | Distant downstream | 0.0558314361428043 | 0.00383136244720992 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs1134452 | chr22:19849559:A:G | Distant downstream | 0.0558314361428043 | 0.00383136244720992 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs11704009 | chr22:19852600:A:G | Distant downstream | 0.0555087717159002 | 0.00400069649531054 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs35169076 | chr22:19853978:T:C | Distant downstream | 0.0555087717159002 | 0.00400069649531054 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs10372 | chr22:19849775:G:A | Distant downstream | 0.0612664004185455 | 0.00461711198572269 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs10427889 | chr22:19844863:C:T | Distant downstream | 0.0533730216016613 | 0.0101504807328436 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs6518588 | chr22:19866459:T:C | Distant downstream | 0.0493060547101772 | 0.0141792823735067 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs34675706 | chr22:19860095:G:A | Distant downstream | 0.0491792254967941 | 0.0144821442067726 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs6518585 | chr22:19861978:C:T | Distant downstream | 0.0491792254967941 | 0.0144821442067726 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs8141433 | chr22:19866483:A:G | Distant downstream | 0.0491792254967941 | 0.0144821442067726 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs28360650 | chr22:19869538:A:G | Distant downstream | 0.0491792254967941 | 0.0144821442067726 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs7288631 | chr22:19848625:C:T | Distant downstream | 0.0606285308951637 | 0.0213104226098661 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs34820460 | chr22:19881687:G:A | Distant downstream | 0.0531452067951683 | 0.0229629832343409 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs35142928 | chr22:19860228:T:C | Distant downstream | 0.0473569975186885 | 0.0304078806833097 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs35374520 | chr22:19863626:A:G | Distant downstream | 0.0473569975186885 | 0.0304078806833097 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs9754418 | chr22:19867210:A:G | Distant downstream | 0.0473569975186885 | 0.0304078806833097 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs12106549 | chr22:19859464:G:T | Distant downstream | 0.0458048161435421 | 0.0305428518511958 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs34545894 | chr22:19870419:C:G | Distant downstream | 0.0461546811746636 | 0.0347473648610096 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs35554477 | chr22:19869038:G:A | Distant downstream | 0.0485282569851373 | 0.0454556653380433 | LGG | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs35934224 | chr22:19885122:C:T | Distant downstream | 0.05229586410477 | 0.0473819697614039 | LGG | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2106140 | chr22:20000722:G:A | Distant upstream | -0.0498408457118085 | 4.5610120415874e-07 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2238791 | chr22:19995588:C:A | Distant upstream | -0.0486546959009049 | 1.3778397626642e-06 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2518825 | chr22:19982441:G:T | Distant upstream | -0.0486655190515591 | 2.12877549762832e-06 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs1990277 | chr22:19982979:G:A | Distant upstream | -0.0486655190515591 | 2.12877549762832e-06 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2531693 | chr22:19997089:C:G | Distant upstream | -0.0478413947928358 | 2.19893295420042e-06 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2238788 | chr22:19992777:C:T | Distant upstream | -0.0483944122566896 | 2.55994107025016e-06 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2238793 | chr22:19999883:C:G | Distant upstream | -0.0416797097720173 | 5.93769796325271e-05 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs2073745 | chr22:19997984:G:A | Distant upstream | -0.0411682142408306 | 7.38673644041042e-05 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs6518598 | chr22:20034415:G:T | Distant upstream | -0.0289739077646039 | 0.0399435756360971 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs5748507 | chr22:20028218:C:T | Distant upstream | -0.0289226150899276 | 0.0400042118201017 | THCA | Female-baised sQTL |
| exon_skip_367534 | chr22:19971215:19971335 | 5CDS-5UTR | rs5748505 | chr22:20027493:C:T | Distant upstream | -0.0274844935366135 | 0.0477958709692428 | THCA | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs9606074 | chr22:19579456:A:T | Distant downstream | 0.134935460222297 | 0.0357604717144322 | PAAD | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs9604980 | chr22:19581010:C:T | Distant downstream | 0.134935460222297 | 0.0357604717144322 | PAAD | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs34760813 | chr22:19581223:C:T | Distant downstream | 0.134935460222297 | 0.0357604717144322 | PAAD | Female-baised sQTL |
| exon_skip_367550 | chr22:19976705:19976723 | In-frame | rs9606075 | chr22:19583047:A:C | Distant downstream | 0.134935460222297 | 0.0357604717144322 | PAAD | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_367536 | chr22:19972357:19972411 | In-frame | rs75767932 | chr22:19995159:T:C | Distant upstream | -0.0378464514820453 | 0.0166102283000897 | LUSC | Male-baised sQTL |
| exon_skip_367537 | chr22:19973118:19973317 | Frame-shift | rs6518598 | chr22:20034415:G:T | Distant upstream | -0.0228336982481111 | 0.0279074124670295 | LUSC | Male-baised sQTL |
| exon_skip_367537 | chr22:19973118:19973317 | Frame-shift | rs12169508 | chr22:19973484:G:C | Proximal upstream | 0.0284483924112666 | 0.0366524437545908 | LUSC | Male-baised sQTL |
| exon_skip_367537 | chr22:19973118:19973317 | Frame-shift | rs12329964 | chr22:19971510:G:A | Distant downstream | 0.0277630691378078 | 0.0481233055178475 | LUSC | Male-baised sQTL |
| exon_skip_367537 | chr22:19973118:19973317 | Frame-shift | rs62223685 | chr22:19972617:G:A | Distant downstream | 0.0277630691378078 | 0.0481233055178475 | LUSC | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of ARVCF |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000099889 | ARVCF | C0036341 | Schizophrenia | 4 | PSYGENET |
| ENSG00000099889 | ARVCF | C0809983 | Schizophrenia and related disorders | 1 | PSYGENET |
