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Gene: ENSG00000090621 |
Summary for PABPC4 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000090621 | Gene symbol | PABPC4 |
| Gene name | poly(A) binding protein cytoplasmic 4 | |
| HGNC | 8557 | |
| Entrez ID | 8761 | |
| Gene type | protein_coding | |
| Synonyms | PABPC4|iPABP|APP-1 | |
| UniProtAcc | Q13310 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PABPC4 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for PABPC4 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PABPC4 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg16510040 | chr1:39576760 | CGI:chr1:39575645-39576995 | UTR,promoter,exon,gene body | 2.11e-01 | 3.46e-01 | -3.13e+00 | 1.72e-03 | 3.48e-03 | -1.34e-01 |
| KIRP | cg24142464 | chr1:39574817 | CGI:chr1:39575645-39576995 | promoter,gene body | 3.97e-01 | 2.80e-01 | 2.86e+00 | 4.20e-03 | 6.14e-03 | 1.17e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for PABPC4 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| STAD | exon_skip_25328 | 6.96e-01 | 8.25e-01 | -4.35e+00 | 1.37e-05 | 3.21e-04 | -1.29e-01 |
| KIRP | exon_skip_25328 | 6.80e-01 | 5.74e-01 | 3.05e+00 | 2.32e-03 | 7.05e-03 | 1.06e-01 |
| CHOL | exon_skip_25328 | 5.70e-01 | 7.53e-01 | -2.92e+00 | 3.51e-03 | 1.32e-02 | -1.83e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| READ | exon_skip_25328 | 5.48e-01 | 6.86e-01 | -3.59e+00 | 3.36e-04 | 4.80e-03 | -1.38e-01 |
Top |
RNA A-to-I editing events in TCGA for PABPC4 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for PABPC4 |
| TFs related to PABPC4. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | ZNF418 | PABPC4 | 3.40e+00 | 2.86e-03 | 4.40e+00 | 9.88e-01 | Female-biased |
| PABPC4 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PABPC4 |
| RBPs related to ES in PABPC4. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | ZFP36 | exon_skip_25337 | 9.35e+00 | 9.91e-01 | 8.94e+00 | 5.86e-03 | Male-biased |
| UVM | ZFP36 | exon_skip_25337 | 9.73e+00 | 9.96e-01 | 9.31e+00 | 2.08e-03 | Male-biased |
| LIHC | PABPC5 | exon_skip_25336 | 7.21e+00 | 8.32e-03 | 7.62e+00 | 9.81e-01 | Female-biased |
| LUSC | HNRNPH2 | exon_skip_25342 | 8.56e+00 | 9.90e-01 | 8.08e+00 | 3.93e-03 | Male-biased |
| CHOL | PCBP2 | exon_skip_25328 | 7.91e+00 | 7.67e-03 | 8.35e+00 | 9.85e-01 | Female-biased |
| READ | HNRNPH2 | exon_skip_25342 | 8.38e+00 | 1.14e-02 | 8.71e+00 | 9.83e-01 | Female-biased |
| THCA | HNRNPH2 | exon_skip_25342 | 8.38e+00 | 9.89e-01 | 8.02e+00 | 3.90e-03 | Male-biased |
| PCPG | ZFP36 | exon_skip_25337 | 9.16e+00 | 7.30e-03 | 9.51e+00 | 9.90e-01 | Female-biased |
| MESO | PCBP2 | exon_skip_25326 | 8.40e+00 | 9.87e-01 | 8.01e+00 | 6.58e-03 | Male-biased |
| MESO | ZFP36 | exon_skip_25337 | 9.06e+00 | 7.82e-03 | 9.44e+00 | 9.89e-01 | Female-biased |
| LGG | PCBP2 | exon_skip_25326 | 8.76e+00 | 9.90e-01 | 8.37e+00 | 5.03e-03 | Male-biased |
| PAAD | BRUNOL4 | exon_skip_25339 | 7.39e+00 | 9.57e-03 | 7.70e+00 | 9.81e-01 | Female-biased |
| PAAD | BRUNOL5 | exon_skip_25339 | 7.42e+00 | 9.66e-03 | 7.72e+00 | 9.81e-01 | Female-biased |
| PAAD | hnRNPLL | exon_skip_25339 | 7.30e+00 | 9.38e-03 | 7.61e+00 | 9.81e-01 | Female-biased |
| PAAD | ZFP36 | exon_skip_25337 | 9.44e+00 | 9.96e-01 | 8.93e+00 | 7.76e-04 | Male-biased |
| KIRC | ZFP36 | exon_skip_25337 | 8.87e+00 | 1.10e-02 | 9.18e+00 | 9.86e-01 | Female-biased |
| BLCA | PCBP2 | exon_skip_25328 | 8.57e+00 | 9.85e-01 | 8.20e+00 | 8.83e-03 | Male-biased |
| BLCA | ZFP36 | exon_skip_25337 | 9.01e+00 | 4.07e-03 | 9.45e+00 | 9.93e-01 | Female-biased |
| SKCM | HNRNPH2 | exon_skip_25342 | 8.32e+00 | 9.90e-01 | 7.82e+00 | 2.47e-03 | Male-biased |
| HNSC | PCBP2 | exon_skip_25326 | 8.81e+00 | 9.83e-01 | 8.49e+00 | 1.23e-02 | Male-biased |
| SARC | ZFP36 | exon_skip_25337 | 8.94e+00 | 1.17e-02 | 9.28e+00 | 9.85e-01 | Female-biased |
| PABPC4 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs60767579 | chr1:38051797:C:T | - | 0.136424631281305 | 2.56685642808394e-05 | LUSC | Female-baised eQTL |
| rs61186346 | chr1:38057373:G:T | - | 0.136424631281305 | 2.56685642808394e-05 | LUSC | Female-baised eQTL |
| rs72962242 | chr1:42330086:G:A | - | 0.136087288053961 | 4.8789397341964e-05 | LUSC | Female-baised eQTL |
| rs11205918 | chr1:38068193:C:T | - | 0.128424665089405 | 8.28878079891931e-05 | LUSC | Female-baised eQTL |
| rs557147 | chr1:38080528:G:A | - | 0.128378128169536 | 8.56311594850541e-05 | LUSC | Female-baised eQTL |
| rs12131530 | chr1:38080626:C:G | - | 0.128378128169536 | 8.56311594850541e-05 | LUSC | Female-baised eQTL |
| rs474975 | chr1:38081267:A:C | - | 0.128378128169536 | 8.56311594850541e-05 | LUSC | Female-baised eQTL |
| rs550582 | chr1:38081582:T:C | - | 0.128378128169536 | 8.56311594850541e-05 | LUSC | Female-baised eQTL |
| rs534782 | chr1:38083175:G:A | - | 0.128378128169536 | 8.56311594850541e-05 | LUSC | Female-baised eQTL |
| rs72918865 | chr1:38083627:T:C | - | 0.128378128169536 | 8.56311594850541e-05 | LUSC | Female-baised eQTL |
| rs477471 | chr1:38087754:T:C | - | 0.128369318768372 | 8.72513862996193e-05 | LUSC | Female-baised eQTL |
| rs12121956 | chr1:38053013:T:C | - | 0.113984758679968 | 0.000522126445448737 | LUSC | Female-baised eQTL |
| rs2889739 | chr1:39523036:A:G | - | 0.12316238994439 | 0.000729704055568564 | LUSC | Female-baised eQTL |
| rs508546 | chr1:33663877:C:T | - | -0.120132761668322 | 0.000971931807634702 | LUSC | Female-baised eQTL |
| rs477882 | chr1:38081625:G:A | - | 0.109002423873485 | 0.00138800041790964 | LUSC | Female-baised eQTL |
| rs1690553 | chr1:33643600:T:G | - | 0.112185351448558 | 0.00198896997128011 | LUSC | Female-baised eQTL |
| rs514427 | chr1:33636872:A:G | - | 0.112162703956945 | 0.00200444289797793 | LUSC | Female-baised eQTL |
| rs72662047 | chr1:33641043:C:T | - | 0.112162703956945 | 0.00200444289797793 | LUSC | Female-baised eQTL |
| rs57590210 | chr1:42107951:C:T | - | 0.102126287645523 | 0.00335881417324634 | LUSC | Female-baised eQTL |
| rs74836434 | chr1:42108511:A:T | - | 0.102126287645523 | 0.00335881417324634 | LUSC | Female-baised eQTL |
| rs58217148 | chr1:42096163:A:G | - | 0.102123832156493 | 0.0033635847674626 | LUSC | Female-baised eQTL |
| rs510533 | chr1:33648074:G:A | - | 0.10570709130681 | 0.00417975975104149 | LUSC | Female-baised eQTL |
| rs640394 | chr1:33648892:G:A | - | 0.10570709130681 | 0.00417975975104149 | LUSC | Female-baised eQTL |
| rs292813 | chr1:33636937:C:T | - | 0.105773072689359 | 0.00419462920363635 | LUSC | Female-baised eQTL |
| rs590210 | chr1:33649668:T:C | - | 0.105724602556877 | 0.00420472865854603 | LUSC | Female-baised eQTL |
| rs653470 | chr1:33647945:A:G | - | 0.105654086017101 | 0.00424687158855312 | LUSC | Female-baised eQTL |
| rs532377 | chr1:33664184:A:T | - | -0.107018577015235 | 0.00428101896340523 | LUSC | Female-baised eQTL |
| rs642676 | chr1:33664541:C:T | - | -0.107018577015235 | 0.00428101896340523 | LUSC | Female-baised eQTL |
| rs16825164 | chr1:38534434:A:C | - | 0.10467942459742 | 0.00428101896340523 | LUSC | Female-baised eQTL |
| rs11210273 | chr1:41482073:G:A | - | 0.108178930759524 | 0.00463290519943298 | LUSC | Female-baised eQTL |
| rs7537583 | chr1:36738405:C:A | - | 0.100268226702919 | 0.00646693605920212 | LUSC | Female-baised eQTL |
| rs644477 | chr1:33670674:A:T | - | -0.101506623412752 | 0.00748203653371772 | LUSC | Female-baised eQTL |
| rs12142615 | chr1:41473424:T:C | - | 0.0984725229578129 | 0.0115908493421614 | LUSC | Female-baised eQTL |
| rs12143601 | chr1:41474351:T:C | - | 0.0984725229578129 | 0.0115908493421614 | LUSC | Female-baised eQTL |
| rs2439650 | chr1:33648477:C:T | - | 0.0956139454963875 | 0.0120292242061138 | LUSC | Female-baised eQTL |
| rs906229 | chr1:36723370:C:T | - | 0.0947649921486133 | 0.0122163159785475 | LUSC | Female-baised eQTL |
| rs72670909 | chr1:38608504:C:T | - | 0.0930711966697455 | 0.0124190583414243 | LUSC | Female-baised eQTL |
| rs61779334 | chr1:39517350:C:G | - | 0.0846351449130263 | 0.0126006867556304 | LUSC | Female-baised eQTL |
| rs71654257 | chr1:42754456:G:T | - | 0.0931802988926678 | 0.016412868546544 | LUSC | Female-baised eQTL |
| rs3738502 | chr1:42755516:C:T | - | 0.0931802988926678 | 0.016412868546544 | LUSC | Female-baised eQTL |
| rs11585208 | chr1:42756768:C:T | - | 0.0931326512451618 | 0.0166915843214239 | LUSC | Female-baised eQTL |
| rs12744838 | chr1:42763388:G:A | - | 0.0931326512451618 | 0.0166915843214239 | LUSC | Female-baised eQTL |
| rs11210269 | chr1:41481664:G:A | - | 0.0939775578433713 | 0.018590277818536 | LUSC | Female-baised eQTL |
| rs11584399 | chr1:39523340:G:A | - | 0.0803945316309786 | 0.0188520880519743 | LUSC | Female-baised eQTL |
| rs7534135 | chr1:33422769:C:T | - | 0.0860315584795731 | 0.019312525698356 | LUSC | Female-baised eQTL |
| rs55860530 | chr1:33434058:C:T | - | 0.0859504631402853 | 0.0195986387598543 | LUSC | Female-baised eQTL |
| rs10493053 | chr1:33423207:T:C | - | 0.0860113661297186 | 0.0196314491342721 | LUSC | Female-baised eQTL |
| rs72660106 | chr1:33423112:T:G | - | 0.0859434107333706 | 0.0198690168397365 | LUSC | Female-baised eQTL |
| rs16835467 | chr1:33426737:T:C | - | 0.085924455898237 | 0.0199439382330673 | LUSC | Female-baised eQTL |
| rs72660114 | chr1:33427582:C:A | - | 0.085924455898237 | 0.0199439382330673 | LUSC | Female-baised eQTL |
| rs55798146 | chr1:33429048:T:C | - | 0.0858615492317203 | 0.0201657278968389 | LUSC | Female-baised eQTL |
| rs12060722 | chr1:38529804:C:T | - | 0.0882192689271103 | 0.0213216477538683 | LUSC | Female-baised eQTL |
| rs72917034 | chr1:38528350:C:T | - | 0.088193200520306 | 0.0216529870815429 | LUSC | Female-baised eQTL |
| rs4970550 | chr1:38532646:C:A | - | 0.0880824901338811 | 0.0217133494250316 | LUSC | Female-baised eQTL |
| rs56059209 | chr1:33414237:A:C | - | 0.0827950883791319 | 0.0270686050697973 | LUSC | Female-baised eQTL |
| rs56084563 | chr1:33416474:G:A | - | 0.0827950883791319 | 0.0270686050697973 | LUSC | Female-baised eQTL |
| rs72660103 | chr1:33420920:C:T | - | 0.0827950883791319 | 0.0270686050697973 | LUSC | Female-baised eQTL |
| rs72658302 | chr1:33418145:T:C | - | 0.0827072125815313 | 0.0277328255039015 | LUSC | Female-baised eQTL |
| rs10890041 | chr1:41475928:T:C | - | 0.0892002546474661 | 0.0288282798403302 | LUSC | Female-baised eQTL |
| rs75470965 | chr1:38548967:G:A | - | 0.08479769867676 | 0.0294468149820624 | LUSC | Female-baised eQTL |
| rs12076633 | chr1:38543653:T:G | - | 0.0845695268367338 | 0.0304021094046151 | LUSC | Female-baised eQTL |
| rs680801 | chr1:33646392:C:G | - | 0.0840941726073624 | 0.0342708142908137 | LUSC | Female-baised eQTL |
| rs72668106 | chr1:36739904:G:T | - | 0.0805382139979168 | 0.0391279248205417 | LUSC | Female-baised eQTL |
| rs11586135 | chr1:39545488:A:T | - | 0.0731962008730116 | 0.0394421976357949 | LUSC | Female-baised eQTL |
| rs41270831 | chr1:39546304:A:C | - | 0.0731962008730116 | 0.0394421976357949 | LUSC | Female-baised eQTL |
| rs61781366 | chr1:39561422:T:C | gene,exon | 0.0731962008730116 | 0.0394421976357949 | LUSC | Female-baised eQTL |
| rs12077500 | chr1:42169834:G:A | - | 0.0802375460477862 | 0.0407764471979725 | LUSC | Female-baised eQTL |
| rs12125163 | chr1:36976293:C:T | - | 0.077966983997341 | 0.0408259283240971 | LUSC | Female-baised eQTL |
| rs12130438 | chr1:36981198:C:T | - | 0.077966983997341 | 0.0408259283240971 | LUSC | Female-baised eQTL |
| rs4427370 | chr1:36738281:C:G | - | 0.0779705663457794 | 0.0410567770495998 | LUSC | Female-baised eQTL |
| rs11210560 | chr1:41994779:A:T | - | 0.0825565593235153 | 0.0424146401566566 | LUSC | Female-baised eQTL |
| rs543735 | chr1:33668240:G:A | - | -0.0835683610462296 | 0.0446007977964302 | LUSC | Female-baised eQTL |
| rs618915 | chr1:33645497:T:C | - | 0.0808252554607883 | 0.0460804298261767 | LUSC | Female-baised eQTL |
| rs11206277 | chr1:39535654:G:A | - | 0.0794717448422396 | 0.0469591746648358 | LUSC | Female-baised eQTL |
| rs11577989 | chr1:39553686:C:T | - | 0.0713401780830255 | 0.0479140577263326 | LUSC | Female-baised eQTL |
| rs11206278 | chr1:39535795:G:A | - | 0.0711221695569995 | 0.0490119444721823 | LUSC | Female-baised eQTL |
| rs35360106 | chr1:39559922:G:T | - | 0.0711221695569995 | 0.0490119444721823 | LUSC | Female-baised eQTL |
| rs12127094 | chr1:39565151:C:T | gene,CDS,exon,UTR | 0.0711221695569995 | 0.0490119444721823 | LUSC | Female-baised eQTL |
| rs57359543 | chr1:34995221:C:A | - | 0.133686854167041 | 0.0490387799669494 | LGG | Female-baised eQTL |
| rs77880053 | chr1:40361750:C:T | - | 0.188701900323388 | 0.0291724221982497 | BLCA | Female-baised eQTL |
| rs78774115 | chr1:40364002:G:C | - | 0.188701900323388 | 0.0291724221982497 | BLCA | Female-baised eQTL |
| rs1391315 | chr1:40386710:T:G | - | 0.188701900323388 | 0.0291724221982497 | BLCA | Female-baised eQTL |
| rs143326400 | chr1:40393563:T:C | - | 0.188701900323388 | 0.0291724221982497 | BLCA | Female-baised eQTL |
| rs11210726 | chr1:42833450:A:G | - | -0.0449590154096024 | 0.013155471735743 | LUAD | Female-baised eQTL |
| rs12124733 | chr1:42830447:G:A | - | 0.0401939211360226 | 0.041155046059047 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs437628 | chr1:30338095:G:A | - | 0.0470425132077503 | 0.00265954375474318 | LUSC | Male-baised eQTL |
| rs453756 | chr1:30336332:C:A | - | 0.0491041441674885 | 0.00429316777836288 | LUSC | Male-baised eQTL |
| rs375489 | chr1:30336626:C:T | - | 0.0490049646464379 | 0.00446026864566785 | LUSC | Male-baised eQTL |
| rs375847 | chr1:30336712:C:T | - | 0.0480732138383548 | 0.00601889881086072 | LUSC | Male-baised eQTL |
| rs376801 | chr1:30336970:C:T | - | 0.0479380157856647 | 0.00635965863738886 | LUSC | Male-baised eQTL |
| rs407838 | chr1:30339980:C:T | - | 0.0465878738251628 | 0.00654346139572059 | LUSC | Male-baised eQTL |
| rs79076950 | chr1:38224325:C:T | - | 0.0460395301253928 | 0.0101025270314063 | LUSC | Male-baised eQTL |
| rs431302 | chr1:30351659:G:A | - | 0.0450380735170168 | 0.0112888531128729 | LUSC | Male-baised eQTL |
| rs423228 | chr1:30344855:T:C | - | 0.0398314794566553 | 0.0287649435295345 | LUSC | Male-baised eQTL |
| rs653960 | chr1:30352608:A:T | - | 0.0395504061254861 | 0.0373680621233879 | LUSC | Male-baised eQTL |
| rs76647746 | chr1:38223746:T:A | - | 0.0416556217229321 | 0.049731581724468 | LUSC | Male-baised eQTL |
| rs56285858 | chr1:31519819:T:C | - | 0.095679701097228 | 0.0395100936631245 | LGG | Male-baised eQTL |
| rs114566385 | chr1:31521631:A:T | - | 0.095679701097228 | 0.0395100936631245 | LGG | Male-baised eQTL |
| rs41263951 | chr1:31523409:C:A | - | 0.095679701097228 | 0.0395100936631245 | LGG | Male-baised eQTL |
| rs72662915 | chr1:31523688:A:G | - | 0.095679701097228 | 0.0395100936631245 | LGG | Male-baised eQTL |
| rs72662918 | chr1:31525603:T:C | - | 0.095679701097228 | 0.0395100936631245 | LGG | Male-baised eQTL |
| rs785109 | chr1:39687724:G:T | - | -0.0612643822251327 | 0.013161089476173 | KIRC | Male-baised eQTL |
| rs785114 | chr1:39689814:A:G | - | -0.0603102967765807 | 0.0158376317807067 | KIRC | Male-baised eQTL |
| rs784632 | chr1:39683137:C:G | - | -0.0577385309385166 | 0.0366126099485616 | KIRC | Male-baised eQTL |
| rs785115 | chr1:39690060:G:A | - | -0.057204882480138 | 0.0370329686941125 | KIRC | Male-baised eQTL |
| rs784627 | chr1:39676623:C:G | - | -0.0575238187291977 | 0.0380892930277714 | KIRC | Male-baised eQTL |
| rs11210738 | chr1:42864104:C:T | - | 0.0415027566751501 | 0.0121825831755161 | BLCA | Male-baised eQTL |
| rs4660234 | chr1:42853601:C:T | - | 0.0386846859795924 | 0.0198033297958243 | BLCA | Male-baised eQTL |
| rs12407411 | chr1:42858007:T:C | - | 0.0379550930062041 | 0.035022665291472 | BLCA | Male-baised eQTL |
| rs12407412 | chr1:42858030:T:C | - | 0.0379550930062041 | 0.035022665291472 | BLCA | Male-baised eQTL |
| rs11576627 | chr1:42860511:C:T | - | 0.0379550930062041 | 0.035022665291472 | BLCA | Male-baised eQTL |
| rs4660235 | chr1:42854764:G:A | - | 0.0367522870856007 | 0.0453606643091003 | BLCA | Male-baised eQTL |
| rs6685920 | chr1:42855805:G:A | - | 0.0366869009516954 | 0.0460503322281547 | BLCA | Male-baised eQTL |
| rs75229446 | chr1:47969362:C:T | - | 0.0665580453723139 | 0.0202968142319106 | COAD | Male-baised eQTL |
| rs3131692 | chr1:39891305:G:T | - | 0.0588966869452775 | 0.0206538134583018 | COAD | Male-baised eQTL |
| rs761164 | chr1:39885979:A:G | - | 0.0587788820549002 | 0.020976940063738 | COAD | Male-baised eQTL |
| rs3131689 | chr1:39893813:C:T | - | 0.058887682228728 | 0.0215691670425045 | COAD | Male-baised eQTL |
| rs58280445 | chr1:33424676:C:T | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs6684564 | chr1:33425530:A:G | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs74651966 | chr1:33430546:C:T | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs140002123 | chr1:33430931:C:G | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs117439736 | chr1:33431053:G:A | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs7516983 | chr1:33431844:T:C | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs4652881 | chr1:33432510:C:T | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs10914713 | chr1:33432896:A:G | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs1324477 | chr1:33434897:T:C | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs1324479 | chr1:33438206:A:G | - | 0.0555597672640485 | 0.0302810876650975 | COAD | Male-baised eQTL |
| rs3845569 | chr1:39882380:G:A | - | 0.0564544672216507 | 0.0302952684504909 | COAD | Male-baised eQTL |
| rs1962275 | chr1:48886574:G:A | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3127558 | chr1:48889803:C:T | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3127560 | chr1:48892322:C:G | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3127561 | chr1:48892910:G:A | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3121520 | chr1:48892951:T:C | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3121523 | chr1:48895959:T:C | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3121524 | chr1:48896226:A:C | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3121525 | chr1:48896318:A:C | - | -0.0665882571821695 | 0.0347651164763727 | COAD | Male-baised eQTL |
| rs3806291 | chr1:35851077:G:C | - | 0.0809100653552066 | 0.0405908068338071 | COAD | Male-baised eQTL |
| rs3930825 | chr1:47816848:A:G | - | -0.038457421492824 | 0.0409400015926578 | COAD | Male-baised eQTL |
| rs11210747 | chr1:42884932:C:T | - | -0.0353826508617823 | 0.0433517771897313 | COAD | Male-baised eQTL |
| rs3127557 | chr1:48885853:G:A | - | -0.0671752283468366 | 0.0463817062353639 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000090621 |
| CpG Site: cg18162350 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.408667407454393 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg18162350 | chr1:39567471 | gene | -0.408667407454393 | 1.15523201166454e-13 | -0.49471302899859987 | 3.7986077977148854e-17 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_25325 | chr1:39563835:39563922 | In-frame | rs11211039 | chr1:38616561:T:C | Distant downstream | -0.0734781203683472 | 1.11209328157725e-05 | COAD | Female-baised sQTL |
| exon_skip_25325 | chr1:39563835:39563922 | In-frame | rs783841 | chr1:39456631:A:T | Distant downstream | -0.0548480373542096 | 0.0491619952705994 | COAD | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_25325 | chr1:39563835:39563922 | In-frame | rs12126362 | chr1:39913612:G:C | Distant upstream | -0.0383792452508967 | 0.0430649083952692 | COAD | Male-baised sQTL |
| exon_skip_25325 | chr1:39563835:39563922 | In-frame | rs12124681 | chr1:39914309:T:C | Distant upstream | -0.0383792452508967 | 0.0430649083952692 | COAD | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of PABPC4 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000090621 | PABPC4 | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
